Biological Process stringlengths 7 1.01k | Cellular Component stringlengths 6 867 | Molecular Function stringlengths 11 871 | Organism stringlengths 8 73 | Keywords stringlengths 1 810 | Sequence 10 stringlengths 5 10 | Sequence stringlengths 5 1.02k | Combined stringlengths 136 3.91k |
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protein N-linked glycosylation | endoplasmic reticulum membrane; Golgi cis cisterna; mannan polymerase complex | alpha-1,6-mannosyltransferase activity glycolipid 1,6-alpha-mannosyltransferase activity | Saccharomyces cerevisiae | Endoplasmic reticulum Glycoprotein Glycosyltransferase Golgi apparatus Membrane Reference proteome Signal-anchor Transferase Transmembrane Transmembrane helix | MSRKLSHLIA | MSRKLSHLIATRKSKTIVVTVLLIYSLLTFHLSNKRLLSQFYPSKDDFKQTLLPTTSHSQDINLKKQITVNKKKNQLHNLRDQLSFAFPYDSQAPIPQRVWQTWKVGADDKNFPSSFRTYQKTWSGSYSPDYQYSLISDDSIIPFLENLYAPVPIVIQAFKLMPGNILKADFLRYLLLFARGGIYSDMDTMLLKPIDSWPSQNKSWLNNIIDLNKPIPYKNSKPSLLSSDEISHQPGLVIGIEADPDRDDWSEWYARRIQFCQWTIQAKPGHPILRELILNITATTLASVQNPGVPVSEMIDPRFEEDYNVNYRHKRRHD... | protein N-linked glycosylation endoplasmic reticulum membrane; Golgi cis cisterna; mannan polymerase complex alpha-1,6-mannosyltransferase activity glycolipid 1,6-alpha-mannosyltransferase activity Saccharomyces cerevisiae Endoplasmic reticulum Glycoprotein Glycosyltransferase Golgi apparatus Membrane Reference proteo... |
CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation cytokine-mediated signaling pathway gene expression immune response interleukin-15-mediated signaling pathway interleukin-2-mediated signaling pathway interleukin-4-mediated signaling pathway interleukin-7-mediated signaling pathway interleukin-9... | cell surface; cytosol; endoplasmic reticulum; endosome; external side of plasma membrane; membrane; nucleoplasm; plasma membrane; receptor complex | coreceptor activity cytokine binding cytokine receptor activity interleukin-15 receptor activity interleukin-2 binding | Homo sapiens | 3D-structure Alternative splicing Cell membrane Direct protein sequencing Disease variant Disulfide bond Glycoprotein Host-virus interaction Membrane Phosphoprotein Receptor Reference proteome SCID Signal Transmembrane Transmembrane helix | MLKPSLPFTS | MLKPSLPFTSLLFLQLPLLGVGLNTTILTPNGNEDTTADFFLTTMPTDSLSVSTLPLPEVQCFVFNVEYMNCTWNSSSEPQPTNLTLHYWYKNSDNDKVQKCSHYLFSEEITSGCQLQKKEIHLYQTFVVQLQDPREPRRQATQMLKLQNLVIPWAPENLTLHKLSESQLELNWNNRFLNHCLEHLVQYRTDWDHSWTEQSVDYRHKFSLPSVDGQKRYTFRVRSRFNPLCGSAQHWSEWSHPIHWGSNTSKENPFLFALEAVVISVGSMGLIISLLCVYFWLERTMPRIPTLKNLEDLVTEYHGNFSAWSGVSKGLAES... | CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation cytokine-mediated signaling pathway gene expression immune response interleukin-15-mediated signaling pathway interleukin-2-mediated signaling pathway interleukin-4-mediated signaling pathway interleukin-7-mediated signaling pathway interleukin-9... |
behavioral fear response fatty acid metabolic process glial cell proliferation hair follicle development lateral ventricle development learning or memory long-term synaptic potentiation negative regulation of fatty acid beta-oxidation negative regulation of protein lipidation phosphatidylcholine acyl-chain remodeling p... | contractile fiber; endoplasmic reticulum; extracellular space; Golgi apparatus; mitochondrion; perinuclear endoplasmic reticulum; protein-lipid complex; synaptic vesicle | benzodiazepine receptor binding fatty-acyl-CoA binding identical protein binding long-chain fatty acyl-CoA binding | Mus musculus | Acetylation Direct protein sequencing Endoplasmic reticulum Golgi apparatus Hydroxylation Lipid-binding Phosphoprotein Reference proteome Transport | MSQAEFDKAA | MSQAEFDKAAEEVKRLKTQPTDEEMLFIYSHFKQATVGDVNTDRPGLLDLKGKAKWDSWNKLKGTSKESAMKTYVEKVDELKKKYGI | behavioral fear response fatty acid metabolic process glial cell proliferation hair follicle development lateral ventricle development learning or memory long-term synaptic potentiation negative regulation of fatty acid beta-oxidation negative regulation of protein lipidation phosphatidylcholine acyl-chain remodeling p... |
protein complex oligomerization viral entry into host cell virion attachment to host cell virus-mediated pore formation in host cell membrane | host cell membrane; host multivesicular body; membrane; T=pseudo3 icosahedral viral capsid | monoatomic ion channel activity structural molecule activity | Simian hepatitis A virus genotype IV ) | Capsid protein Host endosome Host membrane Host-virus interaction Ion channel Ion transport Membrane T=pseudo3 icosahedral capsid protein Transport Viral attachment to host cell Viral ion channel Virion Virus entry into host cell | MNMARQGLFQ | MNMARQGLFQTVGSGLDHILSLADVEEEQMIQSVDRTAVTGASYFTSVDQSSVHTAEVGSHQSEPLKTSVDKPGSKKTQGEKFFLIHSADWLSTHALFHEVAKLDVVSLLYNEQFAVQGLLRYHTYARFGIEIQVQINPTPFQQGGLICAMVPGDQGYGSIASLTVYPHGLLNCNINNVVRIKVPFIYTRGAYHFKDPQYPVWELTIRVWSEFNIGTGTSAYTSLNVLARFTDLELHGLTPLSTQMMRNEFRVSTTENVVNLSNYEDARAKMSFALDQENWRSDPSEGGGIKITHFSTWTSIPTLAAQFAFNASASVGQQ... | protein complex oligomerization viral entry into host cell virion attachment to host cell virus-mediated pore formation in host cell membrane host cell membrane; host multivesicular body; membrane; T=pseudo3 icosahedral viral capsid monoatomic ion channel activity structural molecule activity Simian hepatitis A virus g... |
fusion of virus membrane with host plasma membrane viral entry into host cell virion attachment to host cell | host cell plasma membrane; membrane; viral envelope; virion membrane | metal ion binding | Radiation murine leukemia virus | Cleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane with host cell membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host membrane Host-virus interaction Lipoprotein Membrane Metal-binding Palmitate Signal Transmembrane Transmembrane helix Viral atta... | MESTTLSKPF | MESTTLSKPFKNQVNPWGPLIVLLILGRVNPVALGNSPHQVFNLSWEVTNEDRETVWAITGNHPLWTWWPDLTPDLCMLALHGPSYWGLEYQAPFSPPPGPPCCSRSSGSTPGCSRDCEEPLTSYTPRCNTAWNRLKLSKVTHAHNEGFYVCPGPHRPRWARSCGGPESFYCASWGCETTGRASWKPSSSWDYITVSNNLTSGQATPVCKNNTWCNSLTIRFTSLGKQATSWVTGHWWGLRLYVSGHDPGLIFGIRLKITDSGPRVPIGPNPVLSDQRPPSQPRSPPHSNSTPTETPLTLPEPPPAGVENRLLNLVKGAY... | fusion of virus membrane with host plasma membrane viral entry into host cell virion attachment to host cell host cell plasma membrane; membrane; viral envelope; virion membrane metal ion binding Radiation murine leukemia virus Cleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane with ... |
carbohydrate metabolic process | extracellular region | alpha-amylase activity cyclomaltodextrin glucanotransferase activity metal ion binding starch binding | Geobacillus stearothermophilus | 3D-structure Calcium Direct protein sequencing Disulfide bond Glycosyltransferase Metal-binding Secreted Signal Transferase | MRRWLSLVLS | MRRWLSLVLSMSFVFSAIFIVSDTQKVTVEAAGNLNKVNFTSDVVYQIVVDRFVDGNTSNNPSGALFSSGCTNLRKYCGGDWQGIINKINDGYLTDMGVTAIWISQPVENVFSVMNDASGSASYHGYWARDFKKPNPFFGTLSDFQRLVDAAHAKGIKVIIDFAPNHTSPASETNPSYMENGRLYDNGTLLGGYTNDANMYFHHNGGTTFSSLEDGIYRNLFDLADLNHQNPVIDRYLKDAVKMWIDMGIDGIRMDAVKHMPFGWQKSLMDEIDNYRPVFTFGEWFLSENEVDANNHYFANESGMSLLDFRFGQKLRQVL... | carbohydrate metabolic process extracellular region alpha-amylase activity cyclomaltodextrin glucanotransferase activity metal ion binding starch binding Geobacillus stearothermophilus 3D-structure Calcium Direct protein sequencing Disulfide bond Glycosyltransferase Metal-binding Secreted Signal Transferase MRRWLSLVLS ... |
clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering viral p... | host cell endosome membrane; host cell plasma membrane; membrane; viral envelope; virion membrane | structural molecule activity | Human immunodeficiency virus type 1 group M subtype B | AIDS Apoptosis Clathrin-mediated endocytosis of virus by host Cleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endosome Host membrane Host-virus interaction Lipoprotein Mem... | MRVKEIRKNY | MRVKEIRKNYQHLWRWGIMLRWGTMLLGMLMICSAAEQLWVTVYYGVPVWKEATTTLFCASDAKAYDTEAHNVWATHACVPTDPNPQEVVLVNVTENFNMWKNNMVEQMHENIISLWDQSLKPCVKLTPLCVTLHCTDLRNTTNNNSSIEEKMKGEIKNCSFNVTTNIRDKVQKEYALFYKLDVVPIDNDNNSTNTCYRLISCDTSVITQACPKVSFEPIPIHYCTPAGFALLKCNNKTFNGTGPCKNVSTVQCTHGIRPVVSTQLLLNGSLAEEGVVIRSENFTDNVKTIIVQLNETVKINCIRPNNKTRKRVTMGPGR... | clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering viral p... |
axon guidance dendrite self-avoidance epithelial to mesenchymal transition homophilic cell adhesion via plasma membrane adhesion molecules | axon; plasma membrane | cell-cell adhesion mediator activity | Bos taurus | Alternative splicing Cell adhesion Cell membrane Direct protein sequencing Disulfide bond Glycoprotein Immunoglobulin domain Membrane Phosphoprotein Reference proteome Repeat Signal Transmembrane Transmembrane helix | MLQTKNLIWT | MLQTKNLIWTLFFLGTAVSLQVDIVPSQGEISVGESKFFLCQVAGDAKDKDISWFSPNGEKLTPNQQRISVVWNDDSSSTLTIYNANIDDAGIYKCVVTAEDGTESEATVNVKIFQKLMFKNAPTPQEFREGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLTNNYLQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPTVQARQSIVNATANLGQSVTLVCNAEGFPEPTVSWTKDGEQIENEEDEKYLFSDDSSELTIRKVDKNDEAEYVCIAENKAGEQDASIHLKVFAKPKITYVENQTAMEL... | axon guidance dendrite self-avoidance epithelial to mesenchymal transition homophilic cell adhesion via plasma membrane adhesion molecules axon; plasma membrane cell-cell adhesion mediator activity Bos taurus Alternative splicing Cell adhesion Cell membrane Direct protein sequencing Disulfide bond Glycoprotein Immunogl... |
fusion of virus membrane with host endosome membrane receptor-mediated endocytosis of virus by host cell virion attachment to host cell | host cell endoplasmic reticulum membrane; host cell Golgi membrane; host cell plasma membrane; membrane; viral envelope; virion membrane | metal ion binding | Tacaribe virus | Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endoplasmic reticulum Host Golgi apparatus Host membrane Host-virus interaction Lipoprotein Membrane Metal-binding Myristate Transmembrane Transmembrane helix Viral attac... | MGQFISFMQE | MGQFISFMQEIPIFLQEALNIALVAVSLICIVKGLVNLYRCGLFQLMVFLVLAGRSCSEETFKIGMHTQFQEVSLSLSALLTNQSHELPMLCLANKTHLYLKSGRSSFKINIDSVTVLTRSADVFVHSPKLGSCFESDEEWVVAWWIEAIGHRWDQDPGLLCRNKTKTEGKLIQINISRADGNVHYGWRLKNGLDHIYRGREEPCFEGEQCLIKIQPEDWPTDCKADHTNTFRFLSRSQKSIAVGRTLKAFFSWSLTDPLGNEAPGGYCLEKWMLVASELKCFGNTAIAKCNQNHDSEFCDMLRLFDYNKNAIKTLNEET... | fusion of virus membrane with host endosome membrane receptor-mediated endocytosis of virus by host cell virion attachment to host cell host cell endoplasmic reticulum membrane; host cell Golgi membrane; host cell plasma membrane; membrane; viral envelope; virion membrane metal ion binding Tacaribe virus Disulfide bon... |
fusion of virus membrane with host endosome membrane receptor-mediated endocytosis of virus by host cell virion attachment to host cell | host cell endoplasmic reticulum membrane; host cell Golgi membrane; host cell plasma membrane; membrane; viral envelope; virion membrane | metal ion binding | Tacaribe virus | Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endoplasmic reticulum Host Golgi apparatus Host membrane Host-virus interaction Lipoprotein Membrane Metal-binding Myristate Transmembrane Transmembrane helix Viral attac... | MGQFISFMQE | MGQFISFMQEIPIFLQEALNIALVAVSLICIVKGLVNLYRCGLFQLMVFLVLAGRSCSEETFKIGMHTQFQEVSLSLSALLTNQSHELPMLCLANKTHLYLKSGRSSFKINIDSVTVLTRSADVFVHSPKLGSCFESDEEWVVAWWIEAIGHRWDQDPGLLCRNKTKTEGKLIQINISRADGNVHYGWRLKNGLDHIYRGREEPCFEGEQCLIKIQPEDWPTDCKADHTNTFRFLSRSQKSIAVGRTLKAFFSWSLTDPLGNVPPGGYCLEKWMLVASELKCFGNTAIAKCNQNHDSEFCDMLRLFDYNKNAIKTLNEET... | fusion of virus membrane with host endosome membrane receptor-mediated endocytosis of virus by host cell virion attachment to host cell host cell endoplasmic reticulum membrane; host cell Golgi membrane; host cell plasma membrane; membrane; viral envelope; virion membrane metal ion binding Tacaribe virus Disulfide bon... |
fusion of virus membrane with host endosome membrane receptor-mediated endocytosis of virus by host cell virion attachment to host cell | host cell endoplasmic reticulum membrane; host cell Golgi membrane; host cell plasma membrane; membrane; viral envelope; virion membrane | metal ion binding | Tacaribe virus | Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endoplasmic reticulum Host Golgi apparatus Host membrane Host-virus interaction Lipoprotein Membrane Metal-binding Myristate Transmembrane Transmembrane helix Viral attac... | MGQFISFMQE | MGQFISFMQEIPIFLQEALNIALVAVSLICIVKGLVNLYRCGLFQLMVFLVLAGRSCSEETFKIGMHTQFQEVSLSLSALLTNQSHELPMLCLANKTHLYLKSGRSSFKINIDSVTVLTRSADVFVHSPKLGSCFESDEEWVVAWWIEAIGHRWDQDPGLLCRNKTKTEGKLIQINISRADGNVHYGWRLKNGLDHIYRGREEPCFEGKQCLIKIQPEDWPTDCKADHTNTFRFLSRSQKSIAVGRTLKAFFSWSLTDPLGNEAPGGYCLEKWMLVASELKCFGTLQCQVQPKSRLRVCDMLRLFDYNKNAIKTLNEETK... | fusion of virus membrane with host endosome membrane receptor-mediated endocytosis of virus by host cell virion attachment to host cell host cell endoplasmic reticulum membrane; host cell Golgi membrane; host cell plasma membrane; membrane; viral envelope; virion membrane metal ion binding Tacaribe virus Disulfide bon... |
clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering viral p... | host cell endosome membrane; host cell plasma membrane; membrane; viral envelope; virion membrane | structural molecule activity | Human immunodeficiency virus type 1 group M subtype B | 3D-structure AIDS Apoptosis Clathrin-mediated endocytosis of virus by host Cleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endosome Host membrane Host-virus interaction Li... | MRVKGIRRNC | MRVKGIRRNCQHLWIWGTMLFGMWMICSAVEQLWVTVYYGVPVWKEATTTLFCASDAKAYSTEAHKVWATHACVPTNPNPQEVVLENVTENFNMWKNNMVEQMHEDIISLWDQSLKPCVKLTPLCVTLNCIDKNITDWENKTIIGGGEVKNCSFNITTSIRDKVHKEYALFYKLDVVPIKSNNDSSTYTRYRLIHCNTSVITQACSKVSFEPIPIHYCAPAGFAILKCNDKKFNGTGPCTNVSTVQCTHGIRPVVSTQLLLNGSLAEEEIVIRSENFTDNAKTIIVHLNESVEINCTRPNNNVRRRHIHIGPGRAFYTGE... | clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering viral p... |
generation of precursor metabolites and energy | cytoplasm; plasma membrane; protein-containing complex | 3 iron, 4 sulfur cluster binding 4 iron, 4 sulfur cluster binding carbon-monoxide dehydrogenase (acceptor) activity carbon-monoxide dehydrogenase (ferredoxin) activity ferrous iron binding nickel cation binding oxidoreductase activity protein homodimerization activity | Rhodospirillum rubrum | 3D-structure 4Fe-4S Cell inner membrane Cell membrane Cytoplasm Direct protein sequencing Iron Iron-sulfur Membrane Metal-binding Nickel Oxidoreductase | MTHHDCAHCS | MTHHDCAHCSSDACATEMLNLAEANSIETAWHRYEKQQPQCGFGSAGLCCRICLKGPCRIDPFGEGPKYGVCGADRDTIVARHLVRMIAAGTAAHSEHGRHIALAMQHISQGELHDYSIRDEAKLYAIAKTLGVATEGRGLLAIVGDLAAITLGDFQNQDYDKPCAWLAASLTPRRVKRLGDLGLLPHNIDASVAQTMSRTHVGCDADPTNLILGGLRVAMADLDGSMLATELSDALFGTPQPVVSAANLGVMKRGAVNIAVNGHNPMLSDIICDVAADLRDEAIAAGAAEGINIIGICCTGHEVMMRHGVPLATNYLSQ... | generation of precursor metabolites and energy cytoplasm; plasma membrane; protein-containing complex 3 iron, 4 sulfur cluster binding 4 iron, 4 sulfur cluster binding carbon-monoxide dehydrogenase (acceptor) activity carbon-monoxide dehydrogenase (ferredoxin) activity ferrous iron binding nickel cation binding oxidore... |
aerobic respiration cellular respiration mitochondrial electron transport, ubiquinol to cytochrome c oxidative phosphorylation response to activity response to alkaloid | mitochondrial inner membrane; mitochondrial respirasome; mitochondrial respiratory chain complex III; mitochondrion | metal ion binding protein-containing complex binding ubiquinol-cytochrome-c reductase activity ubiquitin protein ligase binding | Homo sapiens | 3D-structure Acetylation Direct protein sequencing Disease variant Electron transport Membrane Mitochondrion Mitochondrion inner membrane Neuropathy Parkinsonism Phosphoprotein Reference proteome Respiratory chain Transit peptide Transport | MAASVVCRAA | MAASVVCRAATAGAQVLLRARRSPALLRTPALRSTATFAQALQFVPETQVSLLDNGLRVASEQSSQPTCTVGVWIDVGSRFETEKNNGAGYFLEHLAFKGTKNRPGSALEKEVESMGAHLNAYSTREHTAYYIKALSKDLPKAVELLGDIVQNCSLEDSQIEKERDVILREMQENDASMRDVVFNYLHATAFQGTPLAQAVEGPSENVRKLSRADLTEYLSTHYKAPRMVLAAAGGVEHQQLLDLAQKHLGGIPWTYAEDAVPTLTPCRFTGSEIRHRDDALPFAHVAIAVEGPGWASPDNVALQVANAIIGHYDCTYGG... | aerobic respiration cellular respiration mitochondrial electron transport, ubiquinol to cytochrome c oxidative phosphorylation response to activity response to alkaloid mitochondrial inner membrane; mitochondrial respirasome; mitochondrial respiratory chain complex III; mitochondrion metal ion binding protein-containin... |
valine catabolic process | mitochondrial matrix; mitochondrion | 3-hydroxyisobutyrate dehydrogenase activity NAD binding NADP binding | Homo sapiens | 3D-structure Acetylation Branched-chain amino acid catabolism Direct protein sequencing Mitochondrion NAD Oxidoreductase Reference proteome Transit peptide | MAASLRLLGA | MAASLRLLGAASGLRYWSRRLRPAAGSFAAVCSRSVASKTPVGFIGLGNMGNPMAKNLMKHGYPLIIYDVFPDACKEFQDAGEQVVSSPADVAEKADRIITMLPTSINAIEAYSGANGILKKVKKGSLLIDSSTIDPAVSKELAKEVEKMGAVFMDAPVSGGVGAARSGNLTFMVGGVEDEFAAAQELLGCMGSNVVYCGAVGTGQAAKICNNMLLAISMIGTAEAMNLGIRLGLDPKLLAKILNMSSGRCWSSDTYNPVPGVMDGVPSANNYQGGFGTTLMAKDLGLAQDSATSTKSPILLGSLAHQIYRMMCAKGYSK... | valine catabolic process mitochondrial matrix; mitochondrion 3-hydroxyisobutyrate dehydrogenase activity NAD binding NADP binding Homo sapiens 3D-structure Acetylation Branched-chain amino acid catabolism Direct protein sequencing Mitochondrion NAD Oxidoreductase Reference proteome Transit peptide MAASLRLLGA MAASLRLLGA... |
de novo' AMP biosynthetic process 'de novo' IMP biosynthetic process 'de novo' XMP biosynthetic process animal organ regeneration brainstem development cellular response to interleukin-7 cerebellum development cerebral cortex development dihydrofolate metabolic process GMP biosynthetic process nucleobase-containing com... | cytosol; extracellular exosome; membrane; plasma membrane | cadherin binding IMP cyclohydrolase activity phosphoribosylaminoimidazolecarboxamide formyltransferase activity protein homodimerization activity | Homo sapiens | 3D-structure Acetylation Alternative splicing Cytoplasm Direct protein sequencing Disease variant Epilepsy Hydrolase Intellectual disability Multifunctional enzyme Purine biosynthesis Reference proteome Transferase | MAPGQLALFS | MAPGQLALFSVSDKTGLVEFARNLTALGLNLVASGGTAKALRDAGLAVRDVSELTGFPEMLGGRVKTLHPAVHAGILARNIPEDNADMARLDFNLIRVVACNLYPFVKTVASPGVTVEEAVEQIDIGGVTLLRAAAKNHARVTVVCEPEDYVVVSTEMQSSESKDTSLETRRQLALKAFTHTAQYDEAISDYFRKQYSKGVSQMPLRYGMNPHQTPAQLYTLQPKLPITVLNGAPGFINLCDALNAWQLVKELKEALGIPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYDLYKTLTPISAAYARARGADRMSSFGDFVA... | de novo' AMP biosynthetic process 'de novo' IMP biosynthetic process 'de novo' XMP biosynthetic process animal organ regeneration brainstem development cellular response to interleukin-7 cerebellum development cerebral cortex development dihydrofolate metabolic process GMP biosynthetic process nucleobase-containing com... |
clearance of foreign intracellular DNA cytidine to uridine editing defense response to virus DNA cytosine deamination DNA demethylation innate immune response negative regulation of single stranded viral RNA replication via double stranded DNA intermediate negative regulation of viral genome replication retrotransposon... | cytoplasm; nucleoplasm; nucleus; P-body | cytidine deaminase activity deoxycytidine deaminase activity RNA binding zinc ion binding | Homo sapiens | 3D-structure Alternative initiation Antiviral defense Cytoplasm Direct protein sequencing Hydrolase Immunity Innate immunity Metal-binding Nucleus Reference proteome Zinc | MEASPASGPR | MEASPASGPRHLMDPHIFTSNFNNGIGRHKTYLCYEVERLDNGTSVKMDQHRGFLHNQAKNLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTHVRLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFKHCWDTFVDHQGCPFQPWDGLDEHSQALSGRLRAILQNQGN | clearance of foreign intracellular DNA cytidine to uridine editing defense response to virus DNA cytosine deamination DNA demethylation innate immune response negative regulation of single stranded viral RNA replication via double stranded DNA intermediate negative regulation of viral genome replication retrotransposon... |
epithelial cell differentiation mRNA splicing, via spliceosome regulation of RNA splicing RNA processing RNA splicing | nucleoplasm; nucleus; ribonucleoprotein complex; spliceosomal complex | RNA binding | Homo sapiens | Acetylation Alternative splicing Direct protein sequencing Isopeptide bond Methylation mRNA processing Nucleus Phosphoprotein Reference proteome Repeat Ribonucleoprotein RNA-binding Ubl conjugation | MDWVMKHNGP | MDWVMKHNGPNDASDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALGKHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLGQRPGPYDRPIGGRGGYYGAGRGSMYDRMRRGGDGYDGGYGGFDDYGGYNNYGYGNDGFDDRMRDGRGMGGHGYGGAGDASSGFHGGHFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRATGEADVEFVTHEDAVAAMSKDKNNMQHRYIELFLNSTPGGGSGMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGG... | epithelial cell differentiation mRNA splicing, via spliceosome regulation of RNA splicing RNA processing RNA splicing nucleoplasm; nucleus; ribonucleoprotein complex; spliceosomal complex RNA binding Homo sapiens Acetylation Alternative splicing Direct protein sequencing Isopeptide bond Methylation mRNA processing Nucl... |
mRNA splicing, via spliceosome regulation of RNA splicing RNA processing | catalytic step 2 spliceosome; cytosol; membrane; nucleoplasm; nucleus; ribonucleoprotein complex | identical protein binding poly(U) RNA binding RNA binding | Homo sapiens | 3D-structure Acetylation Direct protein sequencing Disease variant Intellectual disability Isopeptide bond Methylation mRNA processing mRNA splicing Nucleus Phosphoprotein Reference proteome Repeat Ribonucleoprotein RNA-binding Spliceosome Ubl conjugation | MMLGTEGGEG | MMLGTEGGEGFVVKVRGLPWSCSADEVQRFFSDCKIQNGAQGIRFIYTREGRPSGEAFVELESEDEVKLALKKDRETMGHRYVEVFKSNNVEMDWVLKHTGPNSPDTANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPNGITLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRPGAGRGYNSIGRGAGFERMRRGAYGGGYGGYDDYNGYNDGYGFGSDRFGRDLNYCFSGMSDHRYGDGGSTFQSTTGHCVHMRGLPYRATENDIYNFFSPLNPVRVHIE... | mRNA splicing, via spliceosome regulation of RNA splicing RNA processing catalytic step 2 spliceosome; cytosol; membrane; nucleoplasm; nucleus; ribonucleoprotein complex identical protein binding poly(U) RNA binding RNA binding Homo sapiens 3D-structure Acetylation Direct protein sequencing Disease variant Intellectual... |
cornification epidermis development keratinization proteolysis | cornified envelope; cytoplasm; cytosol; keratin filament; mitochondrion; nucleoplasm; nucleus | cysteine-type endopeptidase activity | Homo sapiens | Cytoplasm Differentiation Direct protein sequencing Hydrolase Ichthyosis Nucleus Protease Reference proteome Thiol protease Zymogen | MSNPRSLEEE | MSNPRSLEEEKYDMSGARLALILCVTKAREGSEEDLDALEHMFRQLRFESTMKRDPTAEQFQEELEKFQQAIDSREDPVSCAFVVLMAHGREGFLKGEDGEMVKLENLFEALNNKNCQALRAKPKVYIIQACRGEQRDPGETVGGDEIVMVIKDSPQTIPTYTDALHVYSTVEGYIAYRHDQKGSCFIQTLVDVFTKRKGHILELLTEVTRRMAEAELVQEGKARKTNPEIQSTLRKRLYLQ | cornification epidermis development keratinization proteolysis cornified envelope; cytoplasm; cytosol; keratin filament; mitochondrion; nucleoplasm; nucleus cysteine-type endopeptidase activity Homo sapiens Cytoplasm Differentiation Direct protein sequencing Hydrolase Ichthyosis Nucleus Protease Reference proteome Thio... |
cytoplasmic sequestering of protein negative regulation of G protein-coupled receptor signaling pathway negative regulation of protein dephosphorylation positive regulation of catalytic activity protein targeting signal transduction | cytoplasm; cytosol; extracellular exosome; focal adhesion; melanosome; membrane; perinuclear region of cytoplasm; vacuolar membrane | cadherin binding enzyme binding histone deacetylase binding identical protein binding phosphoprotein binding phosphoserine residue binding protein domain specific binding protein kinase inhibitor activity | Homo sapiens | 3D-structure Acetylation Alternative initiation Cytoplasm Direct protein sequencing Host-virus interaction Isopeptide bond Membrane Nitration Phosphoprotein Reference proteome Ubl conjugation Vacuole | MTMDKSELVQ | MTMDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTERNEKKQQMGKEYREKIEAELQDICNDVLELLDKYLIPNATQPESKVFYLKMKGDYFRYLSEVASGDNKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTSENQGDEGDAGEGEN | cytoplasmic sequestering of protein negative regulation of G protein-coupled receptor signaling pathway negative regulation of protein dephosphorylation positive regulation of catalytic activity protein targeting signal transduction cytoplasm; cytosol; extracellular exosome; focal adhesion; melanosome; membrane; perinu... |
establishment of skin barrier intrinsic apoptotic signaling pathway in response to DNA damage keratinization keratinocyte development keratinocyte proliferation negative regulation of cysteine-type endopeptidase activity involved in apoptotic process negative regulation of innate immune response negative regulation of ... | cytoplasm; cytosol; extracellular exosome; extracellular space; nucleus | cadherin binding identical protein binding phosphoserine residue binding protein kinase binding protein kinase C inhibitor activity protein sequestering activity | Homo sapiens | 3D-structure Alternative splicing Cytoplasm Direct protein sequencing Nucleus Phosphoprotein Reference proteome Secreted Ubl conjugation | MERASLIQKA | MERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSCEERNLLSVAYKNVVGGQRAAWRVLSSIEQKSNEEGSEEKGPEVREYREKVETELQGVCDTVLGLLDSHLIKEAGDAESRVFYLKMKGDYYRYLAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFHYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWTADNAGEEGGEAPQEPQS | establishment of skin barrier intrinsic apoptotic signaling pathway in response to DNA damage keratinization keratinocyte development keratinocyte proliferation negative regulation of cysteine-type endopeptidase activity involved in apoptotic process negative regulation of innate immune response negative regulation of ... |
cellular response to interleukin-7 | cytosol; dynein axonemal particle; Golgi apparatus; nucleus; protein folding chaperone complex; protein-containing complex | Hsp90 protein binding RNA binding | Homo sapiens | 3D-structure Acetylation Alternative splicing Cytoplasm Direct protein sequencing Isopeptide bond Nucleus Phosphoprotein Reference proteome Repeat TPR repeat Ubl conjugation | MEQVNELKEK | MEQVNELKEKGNKALSVGNIDDALQCYSEAIKLDPHNHVLYSNRSAAYAKKGDYQKAYEDGCKTVDLKPDWGKGYSRKAAALEFLNRFEEAKRTYEEGLKHEANNPQLKEGLQNMEARLAERKFMNPFNMPNLYQKLESDPRTRTLLSDPTYRELIEQLRNKPSDLGTKLQDPRIMTTLSVLLGVDLGSMDEEEEIATPPPPPPPKKETKPEPMEEDLPENKKQALKEKELGNDAYKKKDFDTALKHYDKAKELDPTNMTYITNQAAVYFEKGDYNKCRELCEKAIEVGRENREDYRQIAKAYARIGNSYFKEEKYKDAI... | cellular response to interleukin-7 cytosol; dynein axonemal particle; Golgi apparatus; nucleus; protein folding chaperone complex; protein-containing complex Hsp90 protein binding RNA binding Homo sapiens 3D-structure Acetylation Alternative splicing Cytoplasm Direct protein sequencing Isopeptide bond Nucleus Phosphopr... |
negative regulation of cell population proliferation negative regulation of DNA replication positive regulation of smooth muscle cell migration signal transduction | adherens junction; cytoplasm; extracellular exosome; extracellular region; extracellular space; nucleus; ruffle; secretory granule lumen | cadherin binding involved in cell-cell adhesion calcium ion binding calcium-dependent protein binding protein homodimerization activity S100 protein binding | Homo sapiens | 3D-structure Acetylation Calcium Cytoplasm Direct protein sequencing Disulfide bond Metal-binding Nucleus Phosphoprotein Reference proteome Repeat | MAKISSPTET | MAKISSPTETERCIESLIAVFQKYAGKDGYNYTLSKTEFLSFMNTELAAFTKNQKDPGVLDRMMKKLDTNSDGQLDFSEFLNLIGGLAMACHDSFLKAVPSQKRT | negative regulation of cell population proliferation negative regulation of DNA replication positive regulation of smooth muscle cell migration signal transduction adherens junction; cytoplasm; extracellular exosome; extracellular region; extracellular space; nucleus; ruffle; secretory granule lumen cadherin binding in... |
dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis epidermal growth factor receptor signaling pathway epithelial cell proliferation involved in mammary gland duct elongation ERBB2-EGFR signaling pathway G protein-coupled receptor signaling pathway glial cell proliferation mammary gla... | cell surface; cytoplasm; extracellular space; membrane; nucleus | cytokine activity epidermal growth factor receptor binding growth factor activity receptor ligand activity transmembrane receptor protein tyrosine kinase activator activity | Mus musculus | Cytokine Disulfide bond EGF-like domain Glycoprotein Growth factor Membrane Reference proteome Signal Transmembrane Transmembrane helix | MRTPLLPLAR | MRTPLLPLARSVLLLLVLGSGHYAAALELNDPSSGKGESLSGDHSAGGLELSVGREVSTISEMPSGSELSTGDYDYSEEYDNEPQISGYIIDDSVRVEQVIKPKKNKTEGEKSTEKPKRKKKGGKNGKGRRNKKKKNPCTAKFQNFCIHGECRYIENLEVVTCNCHQDYFGERCGEKSMKTHSEDDKDLSKIAVVAVTIFVSAIILAAIGIGIVITVHLWKRYFREYEGETEERRRLRQENGTVHAIA | dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis epidermal growth factor receptor signaling pathway epithelial cell proliferation involved in mammary gland duct elongation ERBB2-EGFR signaling pathway G protein-coupled receptor signaling pathway glial cell proliferation mammary gla... |
actin filament bundle assembly establishment or maintenance of apical/basal cell polarity positive regulation of early endosome to late endosome transport positive regulation of protein localization to early endosome regulation of cell shape regulation of organelle assembly | actin cytoskeleton; actin filament; adherens junction; apical part of cell; apical plasma membrane; basolateral plasma membrane; cell cortex; ciliary basal body; filopodium; microvillus; microvillus membrane; plasma membrane; ruffle membrane; uropod | actin binding actin filament binding cell adhesion molecule binding | Bos taurus | Acetylation Cell membrane Cell projection Cell shape Coiled coil Cytoplasm Cytoskeleton Direct protein sequencing Membrane Phosphoprotein Reference proteome S-nitrosylation | MPKPINVRVT | MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLQYVDNKGFPTWLKLDKKVSAQEVRKESPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPETAVLLGSYAVQAKFGDYNKELHKAGYLGSERLIPQRVMDQHKLTRDQWEDRIQVWHAEHRGMLKDSAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQLER... | actin filament bundle assembly establishment or maintenance of apical/basal cell polarity positive regulation of early endosome to late endosome transport positive regulation of protein localization to early endosome regulation of cell shape regulation of organelle assembly actin cytoskeleton; actin filament; adherens ... |
cellular aromatic compound metabolic process | cytoplasm | intramolecular oxidoreductase activity, interconverting keto- and enol-groups protein homodimerization activity | Escherichia coli | 3D-structure Cytoplasm Isomerase Reference proteome | MPHIDIKCFP | MPHIDIKCFPRELDEQQKAALAADITDVIIRHLNSKDSSISIALQQIQPESWQAIWDAEIAPQMEALIKKPGYSMNA | cellular aromatic compound metabolic process cytoplasm intramolecular oxidoreductase activity, interconverting keto- and enol-groups protein homodimerization activity Escherichia coli 3D-structure Cytoplasm Isomerase Reference proteome MPHIDIKCFP MPHIDIKCFPRELDEQQKAALAADITDVIIRHLNSKDSSISIALQQIQPESWQAIWDAEIAPQMEALIKKPGY... |
cell surface receptor signaling pathway immune response regulation of immune response | cytoplasm; membrane; plasma membrane | IgG binding transmembrane signaling receptor activity | Homo sapiens | 3D-structure Alternative splicing Cell membrane Cytoplasm Disulfide bond Glycoprotein IgG-binding protein Immunoglobulin domain Membrane Phosphoprotein Receptor Reference proteome Repeat Signal Transmembrane Transmembrane helix | MGILSFLPVL | MGILSFLPVLATESDWADCKSPQPWGHMLLWTAVLFLAPVAGTPAAPPKAVLKLEPQWINVLQEDSVTLTCRGTHSPESDSIQWFHNGNLIPTHTQPSYRFKANNNDSGEYTCQTGQTSLSDPVHLTVLSEWLVLQTPHLEFQEGETIVLRCHSWKDKPLVKVTFFQNGKSKKFSRSDPNFSIPQANHSHSGDYHCTGNIGYTLYSSKPVTITVQAPSSSPMGIIVAVVTGIAVAAIVAAVVALIYCRKKRISANSTDPVKAAQFEPPGRQMIAIRKRQPEETNNDYETADGGYMTLNPRAPTDDDKNIYLTLPPNDHVN... | cell surface receptor signaling pathway immune response regulation of immune response cytoplasm; membrane; plasma membrane IgG binding transmembrane signaling receptor activity Homo sapiens 3D-structure Alternative splicing Cell membrane Cytoplasm Disulfide bond Glycoprotein IgG-binding protein Immunoglobulin domain Me... |
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules immune response | azurophil granule membrane; cell surface; extracellular exosome; extracellular space; plasma membrane; side of membrane; specific granule membrane; tertiary granule membrane | protein heterodimerization activity | Homo sapiens | 3D-structure Cell adhesion Cell membrane Disulfide bond Glycoprotein GPI-anchor Immunoglobulin domain Lipoprotein Membrane Reference proteome Repeat Signal | MGPISAPSCR | MGPISAPSCRWRIPWQGLLLTASLFTFWNPPTTAQLTIEAVPSNAAEGKEVLLLVHNLPQDPRGYNWYKGETVDANRRIIGYVISNQQITPGPAYSNRETIYPNASLLMRNVTRNDTGSYTLQVIKLNLMSEEVTGQFSVHPETPKPSISSNNSNPVEDKDAVAFTCEPETQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTLLSVTRNDVGPYECEIQNPASANFSDPVTLNVLYGPDAPTISPSDTYYHAGVNLNLSCHAASNPPSQYSWSVNGTFQQYTQKLFIPNITTKNSGSYACHTTNSATGRNRTTVRMITVSD... | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules immune response azurophil granule membrane; cell surface; extracellular exosome; extracellular space; plasma membrane; side of membrane; specific granule membrane; tertiary granule membrane protein heterodimerization activity Homo sapiens 3D-st... |
apoptotic process mitochondrial ADP transmembrane transport mitochondrial ATP transmembrane transport negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway | membrane; mitochondrial inner membrane | ATP:ADP antiporter activity | Bos taurus | Acetylation Antiport Apoptosis Direct protein sequencing Membrane Methylation Mitochondrion Mitochondrion inner membrane Reference proteome Repeat Transmembrane Transmembrane helix Transport | MTEQAISFAK | MTEQAISFAKDFLAGGIAAAISKTAVAPIERVKLLLQVQHASKQIAADKQYKGIVDCIVRIPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWRYFAGNLASGGAAGATSLCFVYPLDFARTRLAADVGKSGSEREFRGLGDCLVKITKSDGIRGLYQGFNVSVQGIIIYRAAYFGIYDTAKGMLPDPKNTHIVVSWMIAQTVTAVAGVVSYPFDTVRRRMMMQSGRKGADIMYKGTVDCWRKILKDEGGKAFFKGAWSNVLRGMGGAFVLVLYDELKKVI | apoptotic process mitochondrial ADP transmembrane transport mitochondrial ATP transmembrane transport negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway membrane; mitochondrial inner membrane ATP:ADP antiporter activity Bos taurus Acetylation Antiport Apoptosis ... |
flagellated sperm motility in utero embryonic development inositol phosphate metabolic process phosphatidylinositol dephosphorylation regulation of protein processing signal transduction spermatogenesis | cytosol; early endosome membrane; endoplasmic reticulum-Golgi intermediate compartment; Golgi apparatus; membrane; phagocytic vesicle membrane; plasma membrane | inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity inositol-1,4,5-trisphosphate 5-phosphatase activity metal ion binding phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity | Homo sapiens | 3D-structure Alternative splicing Cytoplasm Cytoplasmic vesicle Direct protein sequencing Endosome Golgi apparatus Hydrolase Lipid metabolism Lipoprotein Magnesium Membrane Metal-binding Methylation Prenylation Reference proteome | MDQSVAIQET | MDQSVAIQETLAEGEYCVIAVQGVLCEGDSRQSRLLGLVRYRLEHGGQEHALFLYTHRRMAITGDDVSLDQIVPVSRDFTLEEVSPDGELYILGSDVTVQLDTAELSLVFQLPFGSQTRMFLHEVARACPGFDSATRDPEFLWLSRYRCAELELEMPTPRGCNSALVTWPGYATIGGGRYPSRKKRWGLEEARPQGAGSVLFWGGAMEKTGFRLMERAHGGGFVWGRSARDGRRDEELEEAGREMSAAAGSRERNTAGGSNFDGLRPNGKGVPMDQSSRGQDKPESLQPRQNKSKSEITDMVRSSTITVSDKAHILSMQK... | flagellated sperm motility in utero embryonic development inositol phosphate metabolic process phosphatidylinositol dephosphorylation regulation of protein processing signal transduction spermatogenesis cytosol; early endosome membrane; endoplasmic reticulum-Golgi intermediate compartment; Golgi apparatus; membrane; ph... |
bile acid metabolic process fatty acid beta-oxidation inositol trisphosphate biosynthetic process intracellular cholesterol transport lipid hydroperoxide transport phospholipid transport positive regulation of apoptotic process positive regulation of cholesterol biosynthetic process positive regulation of cholesterol i... | cytoplasm; endoplasmic reticulum; mitochondrion; nucleoplasm; peroxisomal matrix; peroxisome; protein-containing complex | acetyl-CoA C-acyltransferase activity acetyl-CoA C-myristoyltransferase activity cholesterol binding cholesterol transfer activity fatty-acyl-CoA binding identical protein binding long-chain fatty acyl-CoA binding oleic acid binding phosphatidylcholine transfer activity phosphatidylethanolamine transfer activity phosph... | Mus musculus | Acetylation Acyltransferase Alternative initiation Cytoplasm Direct protein sequencing Endoplasmic reticulum Lipid metabolism Lipid transport Lipid-binding Mitochondrion Peroxisome Phosphoprotein Reference proteome Transferase Transport | MPSVALKSPR | MPSVALKSPRLRRVFVVGVGMTKFMKPGGENSRDYPDMAKEAGQKALEDAQIPYSAVEQACVGYVYGDSTSGQRAIYHSLGLTGIPIINVNNNCSTGSTALFMAHQLIQGGLANCVLALGFEKMERGSIGTKFSDRTTPTDKHIEVLIDKYGLSAHPITPQMFGYAGKEHMEKYGTKVEHFAKIGWKNHKHSVNNTYSQFQDEYSLEEVMKSKPVFDFLTILQCCPTSDGAAAAILSSEEFVQQYGLQSKAVEIVAQEMMTDLPSTFEEKSIIKVVGYDMSKEAARRCYEKSGLTPNDVDVIELHDCFSVNELITYEALG... | bile acid metabolic process fatty acid beta-oxidation inositol trisphosphate biosynthetic process intracellular cholesterol transport lipid hydroperoxide transport phospholipid transport positive regulation of apoptotic process positive regulation of cholesterol biosynthetic process positive regulation of cholesterol i... |
feeding behavior habituation larval feeding behavior larval locomotory behavior long-term memory motor neuron axon guidance protein phosphorylation regulation of heart contraction regulation of response to food response to sucrose short-term memory | cytoplasm; cytosol; plasma membrane | ATP binding cGMP binding cGMP-dependent protein kinase activity protein serine kinase activity | Drosophila melanogaster | Alternative splicing ATP-binding cGMP cGMP-binding Kinase Nucleotide-binding Reference proteome Serine/threonine-protein kinase Transferase | MKIKHYPGKA | MKIKHYPGKAVDASLSLEGSSAMGALYEANWLRAANQPAAPATTGTKLSRQSSSAGSSFLIEGISALSKYQMTLENIRQLELQSRDKRIASTIKELSGYRPSALQHHQQQQMHNVWVAEDQDQEHEELEDASEGKEKLASIQEPPAVNHYVLDPTERPRVPRPRQQFSVKPPSLRRSQTMSQPPSYATLRSPPKIKENLSKSSSAYSTFSSAAEDSQDQVVICQQPQRLMAPPPREPPPEPPKRVSKPLSRSQTSVQRYATVRMPNQTTSFSRSVVRSRDSTASQRRLSLEQAIEGLKLEGEKAVRQKSPQISPAASSNG... | feeding behavior habituation larval feeding behavior larval locomotory behavior long-term memory motor neuron axon guidance protein phosphorylation regulation of heart contraction regulation of response to food response to sucrose short-term memory cytoplasm; cytosol; plasma membrane ATP binding cGMP binding cGMP-depen... |
anatomical structure morphogenesis anterior/posterior axis specification, embryo blastoderm segmentation cell differentiation heart development heart formation mesoderm formation negative regulation of transcription by RNA polymerase II periodic partitioning by pair rule gene regulation of gene expression regulation of... | nucleus | DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding | Drosophila melanogaster | Developmental protein DNA-binding Nucleus Pair-rule protein Reference proteome Transcription Transcription regulation | MVKSEMEFKS | MVKSEMEFKSNFSIDAILAKKPINTATQPIKTEPVHHHHQYVHPYSNSDGELSASEDFDSPSRTSTPMSSAAESLSSQNNDKLDVEFDDELEDQLDEDQESEDGNPSKKQKMTAGSDTKKPPYSYNALIMMAIQDSPEQRLTLNGIYQYLINRFPYFKANKRGWQNSIRHNLSLNKCFTKIPRSYDDPGKGNYWILDPSAEEVFIGETTGKLRRKNPGASRTRLAAYRQAIFSPMMAASPYGAPAPSYGYPAVPFAAAAAAALYQRMNPAAYQAAYQQMQYQQAPQAHHHQAPHPAQMQGYPPQLNAELFQRMQFFGKFP... | anatomical structure morphogenesis anterior/posterior axis specification, embryo blastoderm segmentation cell differentiation heart development heart formation mesoderm formation negative regulation of transcription by RNA polymerase II periodic partitioning by pair rule gene regulation of gene expression regulation of... |
dehydroascorbic acid transport galactose transmembrane transport glucose import glucose transmembrane transport monosaccharide transmembrane transport negative regulation of apoptotic process | acrosomal membrane; aggresome; caveola; cell projection; cytoplasm; glutamatergic synapse; membrane; perikaryon; plasma membrane; synaptic membrane; synaptic vesicle membrane | D-glucose transmembrane transporter activity dehydroascorbic acid transmembrane transporter activity galactose transmembrane transporter activity galactoside binding glucose binding glucose transmembrane transporter activity kinase binding monosaccharide transmembrane transporter activity xylose binding | Mus musculus | Cell membrane Cell projection Direct protein sequencing Glycoprotein Membrane Phosphoprotein Reference proteome Sugar transport Transmembrane Transmembrane helix Transport | MGTTKVTPSL | MGTTKVTPSLVFAVTVATIGSFQFGYNTGVINAPETILKDFLNYTLEERLEDLPSEGLLTALWSLCVAIFSVGGMIGSFSVGLFVNRFGRRNSMLLVNLLAIIAGCLMGFAKIAESVEMLILGRLLIGIFCGLCTGFVPMYIGEVSPTALRGAFGTLNQLGIVVGILVAQIFGLDFILGSEELWPGLLGLTIIPAILQSAALPFCPESPRFLLINKKEEDQATEILQRLWGTSDVVQEIQEMKDESVRMSQEKQVTVLELFRSPNYVQPLLISIVLQLSQQLSGINAVFYYSTGIFKDAGVQEPIYATIGAGVVNTIFTV... | dehydroascorbic acid transport galactose transmembrane transport glucose import glucose transmembrane transport monosaccharide transmembrane transport negative regulation of apoptotic process acrosomal membrane; aggresome; caveola; cell projection; cytoplasm; glutamatergic synapse; membrane; perikaryon; plasma membrane... |
complement activation, alternative pathway Notch signaling pathway proteolysis response to bacterium retina development in camera-type eye vascular associated smooth muscle cell differentiation | extracellular space | endopeptidase activity serine-type endopeptidase activity | Rattus norvegicus | Complement alternate pathway Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Immunity Innate immunity Protease Reference proteome Secreted Serine protease Signal Zymogen | MHSSVYLVAL | MHSSVYLVALVVLEAAVCVAQPRGRILGGQEAMAHARPYMASVQVNGTHVCGGTLVDEQWVLSAAHCMDGVTKDEVVQVLLGAHSLSSPEPYKHLYDVQSVVLHPGSRPDSVEDDLMLFKLSHNASLGPHVRPLPLQREDREVKPGTLCDVAGWGVVTHAGRRPDVLQQLTVSIMDRNTCNLRTYHDGAITKNMMCAESNRRDTCRGDSGGPLVCGDAVEAVVTWGSRVCGNRRKPGVFTRVATYVPWIENVLSGNVSVNVTA | complement activation, alternative pathway Notch signaling pathway proteolysis response to bacterium retina development in camera-type eye vascular associated smooth muscle cell differentiation extracellular space endopeptidase activity serine-type endopeptidase activity Rattus norvegicus Complement alternate pathway D... |
de novo' GDP-L-fucose biosynthetic process colanic acid biosynthetic process | cytoplasm | GDP-L-fucose synthase activity isomerase activity NADP+ binding protein homodimerization activity | Escherichia coli | 3D-structure Cytoplasm Isomerase Multifunctional enzyme NADP Oxidoreductase Reference proteome | MSKQRVFIAG | MSKQRVFIAGHRGMVGSAIRRQLEQRGDVELVLRTRDELNLLDSRAVHDFFASERIDQVYLAAAKVGGIVANNTYPADFIYQNMMIESNIIHAAHQNDVNKLLFLGSSCIYPKLAKQPMAESELLQGTLEPTNEPYAIAKIAGIKLCESYNRQYGRDYRSVMPTNLYGPHDNFHPSNSHVIPALLRRFHEATAQNAPDVVVWGSGTPMREFLHVDDMAAASIHVMELAHEVWLENTQPMLSHINVGTGVDCTIRELAQTIAKVVGYKGRVVFDASKPDGTPRKLLDVTRLHQLGWYHEISLEAGLASTYQWFLENQDRFR... | de novo' GDP-L-fucose biosynthetic process colanic acid biosynthetic process cytoplasm GDP-L-fucose synthase activity isomerase activity NADP+ binding protein homodimerization activity Escherichia coli 3D-structure Cytoplasm Isomerase Multifunctional enzyme NADP Oxidoreductase Reference proteome MSKQRVFIAG MSKQRVFIAGHR... |
IRES-dependent viral translational initiation nuclear histone mRNA catabolic process positive regulation of translation protein localization to cytoplasmic stress granule tRNA 3'-end processing tRNA 5'-leader removal tRNA export from nucleus tRNA processing | cytoplasm; cytoplasmic stress granule; cytosol; nucleus; ribonucleoprotein complex | mRNA binding poly(U) RNA binding RNA binding sequence-specific mRNA binding tRNA binding | Mus musculus | Acetylation Nucleus Phosphoprotein Reference proteome RNA-binding | MAENGDNEKM | MAENGDNEKMTALEAKICHQIEYYFGDFNLPRDKFLKEQIKLDEGWVPLETMIKFNRLNRLTTDFNVIVQALSKSKAKLMEVSADKTKIRRSPSRPLPEVTDEYKNDVKNRSVYIKGFPTDATLDDIKEWLDDKGQILNIQMRRTLHKTFKGSIFAVFDSIQSAKKFVEIPGQKYKDTNLLILFKEDYFAKKNEERKQSKVEAKLKAKQEHEGRHKPGSTETRALEGKMGCLLKFSGDLDDQTCREDLHFLFSNHGEIKWVDFARGAKEGIILFKEKAKEALEKARNANNGNLLLRNKKVTWKVLEGHAEKEALKKITDD... | IRES-dependent viral translational initiation nuclear histone mRNA catabolic process positive regulation of translation protein localization to cytoplasmic stress granule tRNA 3'-end processing tRNA 5'-leader removal tRNA export from nucleus tRNA processing cytoplasm; cytoplasmic stress granule; cytosol; nucleus; ribon... |
regulation of auxin biosynthetic process tryptophan biosynthetic process | chloroplast | anthranilate synthase activity metal ion binding | Arabidopsis thaliana | Acetylation Alternative splicing Amino-acid biosynthesis Aromatic amino acid biosynthesis Chloroplast Lyase Magnesium Metal-binding Plastid Reference proteome Transit peptide Tryptophan biosynthesis | MSSSMNVATM | MSSSMNVATMQALTFSRRLLPSVASRYLSSSSVTVTGYSGRSSAYAPSFRSIKCVSVSPEASIVSDTKKLADASKSTNLIPIYRCIFSDQLTPVLAYRCLVKEDDREAPSFLFESVEPGSQMSSVGRYSVVGAQPAMEIVAKENKVIVMDHNNETMTEEFVEDPMEIPRKISEKWNPDPQLVQDLPDAFCGGWVGFFSYDTVRYVEKRKLPFSKAPEDDRNLPDMHLGLYDDVVVFDHVEKKAYVIHWIRLDGSLPYEKAYSNGMQHLENLVAKLHDIEPPKLAAGNVNLQTRQFGPSLDNSNVTCEEYKEAVVKAKEHI... | regulation of auxin biosynthetic process tryptophan biosynthetic process chloroplast anthranilate synthase activity metal ion binding Arabidopsis thaliana Acetylation Alternative splicing Amino-acid biosynthesis Aromatic amino acid biosynthesis Chloroplast Lyase Magnesium Metal-binding Plastid Reference proteome Transi... |
endoplasmic reticulum to Golgi vesicle-mediated transport intra-Golgi vesicle-mediated transport intracellular protein transport protein secretion retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum | COPI vesicle coat; endoplasmic reticulum; endoplasmic reticulum-Golgi intermediate compartment; endosome; Golgi membrane | structural molecule activity | Saccharomyces cerevisiae | Cytoplasm Cytoplasmic vesicle Endosome ER-Golgi transport Golgi apparatus Isopeptide bond Membrane Phosphoprotein Protein transport Reference proteome Repeat Transport Ubl conjugation | MSAHTYKKFE | MSAHTYKKFENSTSGDLPDKMTIYQDCMNTFNESPVNSKRCRLLISRLLRLLAQGETFPQNEATALFFSISKLFQHQNDPLRQAVYLAIKELSGISEDVLMATSSIMKDVQNGSDLIKPDAIRSLTYVLDESTAFSAERLLKSAVVSRHPSISSAALCTSYHLLPISEVTIRRFTNETQEAVLDLKQFPNQHGNSEYYPNSTYISQYHALGLLYQLKKTDKMALLKLVRHFSENNSMKNQLAKVELVKIVNDLIYRDPQLFSQFRPLLSDWLSNKFESVQLETAKLITSFATRNSRLVAPELYAAAISALQSLLTVPRVS... | endoplasmic reticulum to Golgi vesicle-mediated transport intra-Golgi vesicle-mediated transport intracellular protein transport protein secretion retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum COPI vesicle coat; endoplasmic reticulum; endoplasmic reticulum-Golgi intermediate compartment; endosom... |
adenohypophysis development adenylate cyclase-activating G protein-coupled receptor signaling pathway cAMP-mediated signaling cell maturation cell surface receptor signaling pathway cellular response to insulin stimulus determination of adult lifespan establishment of localization in cell growth hormone secretion hormo... | cell surface; cytoplasm; membrane; nuclear inner membrane; nuclear matrix; nuclear outer membrane; plasma membrane; sarcolemma; secretory granule | G protein-coupled peptide receptor activity growth factor binding growth hormone-releasing hormone receptor activity peptide hormone binding | Mus musculus | Cell membrane Disease variant Disulfide bond G-protein coupled receptor Glycoprotein Membrane Receptor Reference proteome Signal Transducer Transmembrane Transmembrane helix | MDGLMWATRI | MDGLMWATRILCLLSLCGVTLGHLHLECDFITQLRDDELACLQAAEGTNNTSLGCPGTWDGLLCWPPTGSGQWVSLPCPEFFSHFGSDTGFVKRDCTITGWSNPFPPYPVACPVPLELLTKEKSYFSTVKIIYTTGHSISIVALCVAIAILVALRRLHCPRNYIHTQLFATFILKASAVFLKDAAIFQGDSTDHCSMSTVLCKVSVAISHLATMTNFSWLLAEAVYLSCLLASTSPRSKPAFWWLVLAGWGLPVLCTGTWVGCKLAFEDTECWDLDNSSPCWWIIKGPIVLSVGVNFGLFLNIICILLRKLEPAQGGLHT... | adenohypophysis development adenylate cyclase-activating G protein-coupled receptor signaling pathway cAMP-mediated signaling cell maturation cell surface receptor signaling pathway cellular response to insulin stimulus determination of adult lifespan establishment of localization in cell growth hormone secretion hormo... |
DNA-templated transcription initiation positive regulation of DNA-templated transcription transcription by RNA polymerase II transcription by RNA polymerase III | nucleus; transcription factor TFIID complex | DNA-binding transcription factor activity minor groove of adenine-thymine-rich DNA binding RNA polymerase II general transcription initiation factor activity RNA polymerase III general transcription initiation factor activity TFIIA-class transcription factor complex binding TFIIB-class transcription factor binding | Caenorhabditis elegans | DNA-binding Nucleus Reference proteome Repeat Transcription | MNLNSPAVSM | MNLNSPAVSMLGGDTPAHGGPNSVLGGQGPSSILTGHGPNSVMGPNSILGPGSVLNPQSIQPMQSQQMHSLQGSSMQMHSHLANSNLNLNINPASVGPDRNPGSVMHHNLDINPPSVAYQNLTVPMTPLAYSVYDRDALTHQAPASNIAATMVPATPASQLDIPMPALQNIVSTVNLGVQLDLKKIALHARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEASRLAARKYARIVQKLGFQAKFTEFMVQNMVGSCDVRFPIQLEGLCITHSQFSTYEPELFPGLIYRMVKPRVVLLIFVSGKVVITGAKT... | DNA-templated transcription initiation positive regulation of DNA-templated transcription transcription by RNA polymerase II transcription by RNA polymerase III nucleus; transcription factor TFIID complex DNA-binding transcription factor activity minor groove of adenine-thymine-rich DNA binding RNA polymerase II genera... |
mitochondrial citrate transmembrane transport | mitochondrial inner membrane; mitochondrion | antiporter activity citrate secondary active transmembrane transporter activity citrate transmembrane transporter activity tricarboxylic acid transmembrane transporter activity | Rattus norvegicus | Antiport Direct protein sequencing Membrane Mitochondrion Mitochondrion inner membrane Phosphoprotein Reference proteome Repeat Transmembrane Transmembrane helix Transport | MAAPRAPRAL | MAAPRAPRALTAAAPGSGKAKLTHPGKAILAGGLAGGIEICITFPTEYVKTQLQLDERANPPRYRGIGDCVRQTVRSHGVLGLYRGLSSLLYGSIPKAAVRFGMFEFLSNHMRDAQGRLDSRRGLLCGLGAGVAEAVVVVCPMETVKVKFIHDQTSSNPKYRGFFHGVREIVREQGLKGTYQGLTATVLKQGSNQAIRFFVMTSLRNWYQGDNPNKPMNPLITGVFGAVAGAASVFGNTPLDVIKTRMQGLEAHKYRNTLDCGVQILKNEGPKAFYKGTVPRLGRVCLDVAIVFVIYDEVVKLLNKVWKTD | mitochondrial citrate transmembrane transport mitochondrial inner membrane; mitochondrion antiporter activity citrate secondary active transmembrane transporter activity citrate transmembrane transporter activity tricarboxylic acid transmembrane transporter activity Rattus norvegicus Antiport Direct protein sequencing ... |
metabolic process suppression by virus of host gene expression | host cell rough endoplasmic reticulum | diphosphoinositol-polyphosphate diphosphatase activity metal ion binding RNA binding | African swine fever virus | 3D-structure Early protein Eukaryotic host gene expression shutoff by virus Host endoplasmic reticulum Host gene expression shutoff by virus Host-virus interaction Hydrolase Late protein Magnesium Manganese Metal-binding Multifunctional enzyme Reference proteome RNA-binding | MDTAMQLKTS | MDTAMQLKTSIGLITCRMNTQNNQIETILVQKRYSLAFSEFIHCHYSINANQGHLIKMFNNMTINERLLVKTLDFDRMWYHIWIETPVYELYHKKYQKFRKNWLLPDNGKKLISLINQAKGSGTLLWEIPKGKPKEDESDLTCAIREFEEETGITREYYQILPEFKKSMSYFDGKTEYKHIYFLAMLCKSLEEPNMNLSLQYENRIAEISKISWQNMEAVRFISKRQSFNLEPMIGPAFNFIKNYLRYKH | metabolic process suppression by virus of host gene expression host cell rough endoplasmic reticulum diphosphoinositol-polyphosphate diphosphatase activity metal ion binding RNA binding African swine fever virus 3D-structure Early protein Eukaryotic host gene expression shutoff by virus Host endoplasmic reticulum Hos... |
protein lipoylation | cytoplasm; cytosol | ATP binding lipoate-protein ligase activity lipoyltransferase activity | Escherichia coli | 3D-structure ATP-binding Cytoplasm Direct protein sequencing Ligase Nucleotide-binding Reference proteome | MSTLRLLISD | MSTLRLLISDSYDPWFNLAVEECIFRQMPATQRVLFLWRNADTVVIGRAQNPWKECNTRRMEEDNVRLARRSSGGGAVFHDLGNTCFTFMAGKPEYDKTISTSIVLNALNALGVSAEASGRNDLVVKTVEGDRKVSGSAYRETKDRGFHHGTLLLNADLSRLANYLNPDKKKLAAKGITSVRSRVTNLTELLPGITHEQVCEAITEAFFAHYGERVEAEIISPNKTPDLPNFAETFARQSSWEWNFGQAPAFSHLLDERFTWGGVELHFDVEKGHITRAQVFTDSLNPAPLEALAGRLQGCLYRADMLQQECEALLVDFP... | protein lipoylation cytoplasm; cytosol ATP binding lipoate-protein ligase activity lipoyltransferase activity Escherichia coli 3D-structure ATP-binding Cytoplasm Direct protein sequencing Ligase Nucleotide-binding Reference proteome MSTLRLLISD MSTLRLLISDSYDPWFNLAVEECIFRQMPATQRVLFLWRNADTVVIGRAQNPWKECNTRRMEEDNVRLARRSSGGG... |
anatomical structure development animal organ morphogenesis circadian rhythm negative regulation of apoptotic process negative regulation of DNA-templated transcription negative regulation of transcription by RNA polymerase II positive regulation of epithelial cell differentiation regulation of cell differentiation reg... | nucleus; transcription regulator complex | DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific double-stranded DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-... | Mus musculus | Alternative splicing Developmental protein Differentiation DNA-binding Homeobox Nucleus Paired box Reference proteome Repressor Transcription Transcription regulation | MQQDGLSSVN | MQQDGLSSVNQLGGLFVNGRPLPLDTRQQIVQLAIRGMRPCDISRSLKVSNGCVSKILGRYYRTGVLEPKCIGGSKPRLATPAVVARIAQLKDEYPALFAWEIQHQLCTEGLCTQDKAPSVSSINRVLRALQEDQSLHWTQLRSPAVLAPVLPSPHSNCGAPRGPHPGTSHRNRTIFSPGQAEALEKEFQRGQYPDSVARGKLAAATSLPEDTVRVWFSNRRAKWRRQEKLKWEAQLPGASQDLTVPKNSPGIISAQQSPGSVPSAALPVLEPLSPSFCQLCCGTAPGRCSSDTSSQAYLQPYWDCQSLLPVASSSYVEF... | anatomical structure development animal organ morphogenesis circadian rhythm negative regulation of apoptotic process negative regulation of DNA-templated transcription negative regulation of transcription by RNA polymerase II positive regulation of epithelial cell differentiation regulation of cell differentiation reg... |
cell redox homeostasis cellular response to oxidative stress defense response to tumor cell extrinsic apoptotic signaling pathway hydrogen peroxide catabolic process leukocyte activation negative regulation of apoptotic process negative regulation of extrinsic apoptotic signaling pathway in absence of ligand negative r... | cytoplasm; cytosol; extracellular exosome | antioxidant activity thioredoxin peroxidase activity | Homo sapiens | 3D-structure Acetylation Alternative splicing Antioxidant Cytoplasm Direct protein sequencing Disulfide bond Oxidoreductase Peroxidase Phosphoprotein Redox-active center Reference proteome | MASGNARIGK | MASGNARIGKPAPDFKATAVVDGAFKEVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFSNRAEDFRKLGCEVLGVSVDSQFTHLAWINTPRKEGGLGPLNIPLLADVTRRLSEDYGVLKTDEGIAYRGLFIIDGKGVLRQITVNDLPVGRSVDEALRLVQAFQYTDEHGEVCPAGWKPGSDTIKPNVDDSKEYFSKHN | cell redox homeostasis cellular response to oxidative stress defense response to tumor cell extrinsic apoptotic signaling pathway hydrogen peroxide catabolic process leukocyte activation negative regulation of apoptotic process negative regulation of extrinsic apoptotic signaling pathway in absence of ligand negative r... |
desensitization of G protein-coupled receptor signaling pathway G protein-coupled receptor internalization positive regulation of ERK1 and ERK2 cascade positive regulation of receptor internalization protein transport receptor internalization signal transduction | clathrin-coated pit; cytoplasm; endocytic vesicle; nucleus | angiotensin receptor binding inositol hexakisphosphate binding molecular adaptor activity phosphatidylinositol binding phosphatidylinositol-3,4,5-trisphosphate binding | Bos taurus | 3D-structure Alternative splicing Cell membrane Coated pit Cytoplasm Cytoplasmic vesicle Hydroxylation Membrane Nucleus Phosphoprotein Protein transport Reference proteome Signal transduction inhibitor Transport Ubl conjugation | MGEKPGTRVF | MGEKPGTRVFKKSSPNCKLTVYLGKRDFVDHLDKVDPVDGVVLVDPDYLKDRKVFVTLTCAFRYGREDLDVLGLSFRKDLFIANYQAFPPTPNPPRPPTRLQERLLRKLGQHAHPFFFTIPQNLPCSVTLQPGPEDTGKACGVDFEIRAFCAKSLEEKSHKRNSVRLVIRKVQFAPEKPGPQPSAETTRHFLMSDRSLHLEASLDKELYYHGEPLNVNVHVTNNSTKTVKKIKVSVRQYADICLFSTAQYKCPVAQVEQDDQVSPSSTFCKVYTITPLLSNNREKRGLALDGKLKHEDTNLASSTIVKEGANKEVLGILV... | desensitization of G protein-coupled receptor signaling pathway G protein-coupled receptor internalization positive regulation of ERK1 and ERK2 cascade positive regulation of receptor internalization protein transport receptor internalization signal transduction clathrin-coated pit; cytoplasm; endocytic vesicle; nucleu... |
protoporphyrinogen IX biosynthetic process | cytoplasm | 4 iron, 4 sulfur cluster binding coproporphyrinogen dehydrogenase activity coproporphyrinogen oxidase activity metal ion binding | Escherichia coli | 3D-structure 4Fe-4S Cytoplasm Direct protein sequencing Iron Iron-sulfur Metal-binding Oxidoreductase Porphyrin biosynthesis Reference proteome S-adenosyl-L-methionine | MSVQQIDWDL | MSVQQIDWDLALIQKYNYSGPRYTSYPTALEFSEDFGEQAFLQAVARYPERPLSLYVHIPFCHKLCYFCGCNKIVTRQQHKADQYLDALEQEIVHRAPLFAGRHVSQLHWGGGTPTYLNKAQISRLMKLLRENFQFNADAEISIEVDPREIELDVLDHLRAEGFNRLSMGVQDFNKEVQRLVNREQDEEFIFALLNHAREIGFTSTNIDLIYGLPKQTPESFAFTLKRVAELNPDRLSVFNYAHLPTIFAAQRKIKDADLPSPQQKLDILQETIAFLTQSGYQFIGMDHFARPDDELAVAQREGVLHRNFQGYTTQGDTD... | protoporphyrinogen IX biosynthetic process cytoplasm 4 iron, 4 sulfur cluster binding coproporphyrinogen dehydrogenase activity coproporphyrinogen oxidase activity metal ion binding Escherichia coli 3D-structure 4Fe-4S Cytoplasm Direct protein sequencing Iron Iron-sulfur Metal-binding Oxidoreductase Porphyrin biosynthe... |
6-sulfoquinovose(1-) catabolic process 6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde carbohydrate phosphorylation | cytosol | 6-deoxy-6-sulfofructose kinase activity ATP binding kinase activity | Escherichia coli | 3D-structure ATP-binding Carbohydrate metabolism Kinase Nucleotide-binding Reference proteome Transferase | MIRVACVGIT | MIRVACVGITVMDRIYYVEGLPTESGKYVARNYTEVGGGPAATAAVAAARLGAQVDFIGRVGDDDTGNSLLAELESWGVNTRYTKRYNQAKSSQSAIMVDTKGERIIINYPSPDLLPDAEWLEEIDFSQWDVVLADVRWHDGAKKAFTLARQAGVMTVLDGDITPQDISELVALSDHAAFSEPGLARLTGVKEMASALKQAQTLTNGHVYVTQGSAGCDWLENGGRQHQPAFKVDVVDTTGAGDVFHGALAVALATSGDLAESVRFASGVAALKCTRPGGRAGIPDCDQTRSFLSLFV | 6-sulfoquinovose(1-) catabolic process 6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde carbohydrate phosphorylation cytosol 6-deoxy-6-sulfofructose kinase activity ATP binding kinase activity Escherichia coli 3D-structure ATP-binding Carbohydrate metabolism Kinase Nucleotide-bindin... |
rhamnose catabolic process | cytoplasm | L-rhamnose mutarotase activity protein homodimerization activity racemase and epimerase activity, acting on carbohydrates and derivatives | Escherichia coli | 3D-structure Carbohydrate metabolism Cytoplasm Isomerase Reference proteome Rhamnose metabolism | MIRKAFVMQV | MIRKAFVMQVNPDAHEEYQRRHNPIWPELEAVLKSHGAHNYAIYLDKARNLLFAMVEIESEERWNAVASTDVCQRWWKYMTDVMPANPDNSPVSSELQEVFYLP | rhamnose catabolic process cytoplasm L-rhamnose mutarotase activity protein homodimerization activity racemase and epimerase activity, acting on carbohydrates and derivatives Escherichia coli 3D-structure Carbohydrate metabolism Cytoplasm Isomerase Reference proteome Rhamnose metabolism MIRKAFVMQV MIRKAFVMQVNPDAHEEYQRR... |
pentose catabolic process rhamnose catabolic process | cytosol | aldehyde-lyase activity identical protein binding metal ion binding rhamnulose-1-phosphate aldolase activity | Escherichia coli | 3D-structure Cytoplasm Lyase Metal-binding Reference proteome Rhamnose metabolism Zinc | MQNITQSWFV | MQNITQSWFVQGMIKATTDAWLKGWDERNGGNLTLRLDDADIAPYHDNFHQQPRYIPLSQPMPLLANTPFIVTGSGKFFRNVQLDPAANLGIVKVDSDGAGYHILWGLTNEAVPTSELPAHFLSHCERIKATNGKDRVIMHCHATNLIALTYVLENDTAVFTRQLWEGSTECLVVFPDGVGILPWMVPGTDEIGQATAQEMQKHSLVLWPFHGVFGSGPTLDETFGLIDTAEKSAQVLVKVYSMGGMKQTISREELIALGKRFGVTPLASALAL | pentose catabolic process rhamnose catabolic process cytosol aldehyde-lyase activity identical protein binding metal ion binding rhamnulose-1-phosphate aldolase activity Escherichia coli 3D-structure Cytoplasm Lyase Metal-binding Reference proteome Rhamnose metabolism Zinc MQNITQSWFV MQNITQSWFVQGMIKATTDAWLKGWDERNGGNLTL... |
L-lyxose metabolic process protein homotetramerization rhamnose catabolic process | cytoplasm; protein-containing complex | identical protein binding L-rhamnose isomerase activity manganese ion binding rhamnose binding zinc ion binding | Escherichia coli | 3D-structure Cytoplasm Isomerase Manganese Metal-binding Reference proteome Rhamnose metabolism Zinc | MTTQLEQAWE | MTTQLEQAWELAKQRFAAVGIDVEEALRQLDRLPVSMHCWQGDDVSGFENPEGSLTGGIQATGNYPGKARNASELRADLEQAMRLIPGPKRLNLHAIYLESDTPVSRDQIKPEHFKNWVEWAKANQLGLDFNPSCFSHPLSADGFTLSHADDSIRQFWIDHCKASRRVSAYFGEQLGTPSVMNIWIPDGMKDITVDRLAPRQRLLAALDEVISEKLNPAHHIDAVESKLFGIGAESYTVGSNEFYMGYATSRQTALCLDAGHFHPTEVISDKISAAMLYVPQLLLHVSRPVRWDSDHVVLLDDETQAIASEIVRHDLFDR... | L-lyxose metabolic process protein homotetramerization rhamnose catabolic process cytoplasm; protein-containing complex identical protein binding L-rhamnose isomerase activity manganese ion binding rhamnose binding zinc ion binding Escherichia coli 3D-structure Cytoplasm Isomerase Manganese Metal-binding Reference prot... |
glycerol metabolic process phosphorylation rhamnose catabolic process | cytosol | ATP binding glycerol kinase activity rhamnulokinase activity | Escherichia coli | 3D-structure ATP-binding Disulfide bond Kinase Magnesium Nucleotide-binding Reference proteome Rhamnose metabolism Transferase | MTFRNCVAVD | MTFRNCVAVDLGASSGRVMLARYERECRSLTLREIHRFNNGLHSQNGYVTWDVDSLESAIRLGLNKVCEEGIRIDSIGIDTWGVDFVLLDQQGQRVGLPVAYRDSRTNGLMAQAQQQLGKRDIYQRSGIQFLPFNTLYQLRALTEQQPELIPHIAHALLMPDYFSYRLTGKMNWEYTNATTTQLVNINSDDWDESLLAWSGANKAWFGRPTHPGNVIGHWICPQGNEIPVVAVASHDTASAVIASPLNGSRAAYLSSGTWSLMGFESQTPFTNDTALAANITNEGGAEGRYRVLKNIMGLWLLQRVLQEQQINDLPALIS... | glycerol metabolic process phosphorylation rhamnose catabolic process cytosol ATP binding glycerol kinase activity rhamnulokinase activity Escherichia coli 3D-structure ATP-binding Disulfide bond Kinase Magnesium Nucleotide-binding Reference proteome Rhamnose metabolism Transferase MTFRNCVAVD MTFRNCVAVDLGASSGRVMLARYERE... |
bis(molybdopterin guanine dinucleotide)molybdenum biosynthetic process | cytoplasm | GTP binding magnesium ion binding molybdenum cofactor guanylyltransferase activity nucleotidyltransferase activity | Escherichia coli | 3D-structure Cytoplasm Direct protein sequencing GTP-binding Magnesium Manganese Metal-binding Molybdenum cofactor biosynthesis Nucleotide-binding Reference proteome Transferase | MNLMTTITGV | MNLMTTITGVVLAGGKARRMGGVDKGLLELNGKPLWQHVADALMTQLSHVVVNANRHQEIYQASGLKVIEDSLADYPGPLAGMLSVMQQEAGEWFLFCPCDTPYIPPDLAARLNHQRKDAPVVWVHDGERDHPTIALVNRAIEPLLLEYLQAGERRVMVFMRLAGGHAVDFSDHKDAFVNVNTPEELARWQEKR | bis(molybdopterin guanine dinucleotide)molybdenum biosynthetic process cytoplasm GTP binding magnesium ion binding molybdenum cofactor guanylyltransferase activity nucleotidyltransferase activity Escherichia coli 3D-structure Cytoplasm Direct protein sequencing GTP-binding Magnesium Manganese Metal-binding Molybdenum c... |
Mo-molybdopterin cofactor biosynthetic process | cytosol | molybdopterin cofactor binding protein homodimerization activity sulfur carrier activity sulfurtransferase activity | Escherichia coli | 3D-structure Cytoplasm Molybdenum cofactor biosynthesis Reference proteome | MKKTQRKEIE | MKKTQRKEIENVTNITGVRQIELWRRDDLQHPRLDEVAEEVPVALVYNGISHVVMMASPKDLEYFALGFSLSEGIIESPRDIFGMDVVPSCNGLEVQIELSSRRFMGLKERRRALAGRTGCGVCGVEQLNDIGKPVQPLPFTQTFDLNKLDDALRHLNDFQPVGQLTGCTHAAAWMLPSGELVGGHEDVGRHVALDKLLGRRSQEGESWQQGAVLVSSRASYEMVQKSAMCGVEILFAVSAATTLAVEVAERCNLTLVGFCKPGRATVYTHPQRLSN | Mo-molybdopterin cofactor biosynthetic process cytosol molybdopterin cofactor binding protein homodimerization activity sulfur carrier activity sulfurtransferase activity Escherichia coli 3D-structure Cytoplasm Molybdenum cofactor biosynthesis Reference proteome MKKTQRKEIE MKKTQRKEIENVTNITGVRQIELWRRDDLQHPRLDEVAEEVPVALV... |
aromatic amino acid family biosynthetic process chorismate metabolic process L-phenylalanine biosynthetic process tyrosine biosynthetic process | cytoplasm; nucleus | chorismate mutase activity tryptophan binding tyrosine binding | Saccharomyces cerevisiae | 3D-structure Allosteric enzyme Amino-acid biosynthesis Aromatic amino acid biosynthesis Cytoplasm Direct protein sequencing Isomerase Phenylalanine biosynthesis Reference proteome Tyrosine biosynthesis | MDFTKPETVL | MDFTKPETVLNLQNIRDELVRMEDSIIFKFIERSHFATCPSVYEANHPGLEIPNFKGSFLDWALSNLEIAHSRIRRFESPDETPFFPDKIQKSFLPSINYPQILAPYAPEVNYNDKIKKVYIEKIIPLISKRDGDDKNNFGSVATRDIECLQSLSRRIHFGKFVAEAKFQSDIPLYTKLIKSKDVEGIMKNITNSAVEEKILERLTKKAEVYGVDPTNESGERRITPEYLVKIYKEIVIPITKEVEVEYLLRRLEE | aromatic amino acid family biosynthetic process chorismate metabolic process L-phenylalanine biosynthetic process tyrosine biosynthetic process cytoplasm; nucleus chorismate mutase activity tryptophan binding tyrosine binding Saccharomyces cerevisiae 3D-structure Allosteric enzyme Amino-acid biosynthesis Aromatic amin... |
hyperosmotic salinity response methionine biosynthetic process phosphatidylinositol phosphate biosynthetic process sulfate assimilation | cytoplasm; nucleus | 3'(2'),5'-bisphosphate nucleotidase activity metal ion binding | Saccharomyces cerevisiae | 3D-structure Cytoplasm Hydrolase Lithium Magnesium Metal-binding Nucleus Reference proteome Stress response | MALERELLVA | MALERELLVATQAVRKASLLTKRIQSEVISHKDSTTITKNDNSPVTTGDYAAQTIIINAIKSNFPDDKVVGEESSSGLSDAFVSGILNEIKANDEVYNKNYKKDDFLFTNDQFPLKSLEDVRQIIDFGNYEGGRKGRFWCLDPIDGTKGFLRGEQFAVCLALIVDGVVQLGCIGCPNLVLSSYGAQDLKGHESFGYIFRAVRGLGAFYSPSSDAESWTKIHVRHLKDTKDMITLEGVEKGHSSHDEQTAIKNKLNISKSLHLDSQAKYCLLALGLADVYLRLPIKLSYQEKIWDHAAGNVIVHEAGGIHTDAMEDVPLDF... | hyperosmotic salinity response methionine biosynthetic process phosphatidylinositol phosphate biosynthetic process sulfate assimilation cytoplasm; nucleus 3'(2'),5'-bisphosphate nucleotidase activity metal ion binding Saccharomyces cerevisiae 3D-structure Cytoplasm Hydrolase Lithium Magnesium Metal-binding Nucleus Ref... |
anatomical structure morphogenesis cell differentiation cellular response to starvation chromatin organization hematopoietic stem cell homeostasis intracellular glucose homeostasis negative regulation of cell population proliferation positive regulation of hepatocyte differentiation positive regulation of transcription... | nucleus | DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific protein domain specific binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding sequence-specific double-stranded DNA binding transcription cis-... | Rattus norvegicus | Activator Chromatin regulator Developmental protein Differentiation DNA-binding Nucleus Reference proteome Transcription Transcription regulation | MLGSVKMEAH | MLGSVKMEAHDLAEWSYYPEAGEVYSPVNPVPTMAPLNSYMSLNPLSSPYPPGGLQASPLPTGPLAPPAPTAPLGPTFPGLGAGSGTGGSASGYGAPGPGLVHGKEMAKGYRRPLTHAKPPYSYISLITMAIQQAPGKMLTLSEIYQWIMDLFPYYRENQQRWQNSIRHSLSFNDCFVKVARSPDKPGKGSYWALHPSSGNMFENGCYLRRQKRFKLEEKAKKGNSATSATRNGTVGSATSATTTAATAVTSPAQPQPTPPSEPEAQSGEDVGGLDCASPPSSAPYFTGLELPGELKLDAPYNFNHPFSINNLMSEQTST... | anatomical structure morphogenesis cell differentiation cellular response to starvation chromatin organization hematopoietic stem cell homeostasis intracellular glucose homeostasis negative regulation of cell population proliferation positive regulation of hepatocyte differentiation positive regulation of transcription... |
glycerol catabolic process glycerol metabolic process glycerol-3-phosphate biosynthetic process phosphorylation triglyceride biosynthetic process triglyceride metabolic process | cytosol; extracellular exosome; mitochondrial outer membrane; mitochondrion; nucleus | ATP binding glycerol kinase activity metal ion binding | Homo sapiens | Alternative splicing ATP-binding Cytoplasm Disease variant Glycerol metabolism Kinase Membrane Metal-binding Mitochondrion Mitochondrion outer membrane Nucleotide-binding Nucleus Reference proteome Transferase Transmembrane Transmembrane helix Zinc | MAASKKAVLG | MAASKKAVLGPLVGAVDQGTSSTRFLVFNSKTAELLSHHQVEIKQEFPREGWVEQDPKEILHSVYECIEKTCEKLGQLNIDISNIKAIGVSNQRETTVVWDKITGEPLYNAVVWLDLRTQSTVESLSKRIPGNNNFVKSKTGLPLSTYFSAVKLRWLLDNVRKVQKAVEEKRALFGTIDSWLIWSLTGGVNGGVHCTDVTNASRTMLFNIHSLEWDKQLCEFFGIPMEILPNVRSSSEIYGLMKISHSVKAGALEGVPISGCLGDQSAALVGQMCFQIGQAKNTYGTGCFLLCNTGHKCVFSDHGLLTTVAYKLGRDKPV... | glycerol catabolic process glycerol metabolic process glycerol-3-phosphate biosynthetic process phosphorylation triglyceride biosynthetic process triglyceride metabolic process cytosol; extracellular exosome; mitochondrial outer membrane; mitochondrion; nucleus ATP binding glycerol kinase activity metal ion binding Hom... |
aflatoxin metabolic process carnitine metabolic process cellular response to fatty acid eating behavior epithelial cell differentiation fatty acid beta-oxidation fatty acid metabolic process glucose metabolic process liver regeneration long-chain fatty acid metabolic process positive regulation of fatty acid beta-oxida... | mitochondrial outer membrane; mitochondrion | carnitine O-palmitoyltransferase activity identical protein binding palmitoleoyltransferase activity | Rattus norvegicus | Acetylation Acyltransferase Direct protein sequencing Fatty acid metabolism Lipid metabolism Membrane Mitochondrion Mitochondrion outer membrane Nitration Phosphoprotein Reference proteome Transferase Transmembrane Transmembrane helix Transport | MAEAHQAVAF | MAEAHQAVAFQFTVTPDGIDLRLSHEALKQICLSGLHSWKKKFIRFKNGIITGVFPANPSSWLIVVVGVISSMHAKVDPSLGMIAKISRTLDTTGRMSSQTKNIVSGVLFGTGLWVAVIMTMRYSLKVLLSYHGWMFAEHGKMSRSTKIWMAMVKVLSGRKPMLYSFQTSLPRLPVPAVKDTVSRYLESVRPLMKEEDFQRMTALAQDFAVNLGPKLQWYLKLKSWWATNYVSDWWEEYIYLRGRGPLMVNSNYYAMEMLYITPTHIQAARAGNTIHAILLYRRTLDREELKPIRLLGSTIPLCSAQWERLFNTSRIPGE... | aflatoxin metabolic process carnitine metabolic process cellular response to fatty acid eating behavior epithelial cell differentiation fatty acid beta-oxidation fatty acid metabolic process glucose metabolic process liver regeneration long-chain fatty acid metabolic process positive regulation of fatty acid beta-oxida... |
adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway chemical synaptic transmission G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger regulation of locomotion | asymmetric synapse; axon terminus; dendrite; glutamatergic synapse; membrane; neuronal cell body; postsynaptic density membrane; presynaptic membrane; synapse | G protein-coupled acetylcholine receptor activity G protein-coupled serotonin receptor activity guanyl-nucleotide exchange factor activity | Mus musculus | Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Membrane Phosphoprotein Postsynaptic cell membrane Receptor Reference proteome Synapse Transducer Transmembrane Transmembrane helix | MANFTPVNGS | MANFTPVNGSSANQSVRLVTTAHNHLETVEMVFIATVTGSLSLVTVVGNILVMLSIKVNRQLQTVNNYFLFSLACADLIIGAFSMNLYTLYIIKGYWPLGAVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPARRTTKMAGLMIAAAWVLSFVLWAPAILFWQFVVGKRTVPDNQCFIQFLSNPAVTFGTAIAAFYLPVVIMTVLYIHISLASRSRVHKHRPEGPKEKKAKTLAFLKSPLMKPSIKKPPPGGASREELRNGKLEEAPPPALPPPPRPVADKDTSNESSSGSATQNTKERPPTELSTTEAATT... | adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway chemical synaptic transmission G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger regulation of locomotion asymmetric synapse; axon terminus; dendrite; glutamatergic synapse; membrane; neuron... |
adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway amylin receptor signaling pathway cell surface receptor signaling pathway cellular response to transforming growth factor beta stimulus cellular response to tumor necrosis ... | acrosomal vesicle; amylin receptor complex 1; amylin receptor complex 2; amylin receptor complex 3; axon; cilium; neuronal cell body; plasma membrane | amylin receptor activity amyloid-beta binding calcitonin binding calcitonin gene-related peptide receptor activity calcitonin receptor activity | Rattus norvegicus | Alternative splicing Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Membrane Receptor Reference proteome Signal Transducer Transmembrane Transmembrane helix | MRFLLLNRFT | MRFLLLNRFTLLLLLLVSPTPVLQAPTNLTDSGLDQEPFLYLVGRKKLLDAQYKCYDRIQQLPPYEGEGPYCNRTWDGWMCWDDTPAGVMSYQHCPDYFPDFDPTEKVSKYCDENGEWFRHPDSNRTWSNYTLCNAFTPDKLHNAYVLYYLALVGHSMSIAALIASMGIFLFFKNLSCQRVTLHKNMFLTYILNSIIIIIHLVEVVPNGDLVRRDPMHIFHHNTYMWTMQWELSPPLPLSAHEGKMDPHDSEVISCKILHFFHQYMMACNYFWMLCEGIYLHTLIVMAVFTEDQRLRWYYLLGWGFPIVPTIIHAITRAV... | adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway amylin receptor signaling pathway cell surface receptor signaling pathway cellular response to transforming growth factor beta stimulus cellular response to tumor necrosis ... |
adenylate cyclase-modulating G protein-coupled receptor signaling pathway cAMP-mediated signaling cell differentiation cell surface receptor signaling pathway development of primary female sexual characteristics multicellular organismal response to stress negative regulation of response to reactive oxygen species posit... | bicellular tight junction; caveola; cell surface; endosome; Golgi membrane; plasma membrane; receptor complex | adenylate cyclase binding G protein-coupled peptide receptor activity neuropeptide binding peptide hormone binding pituitary adenylate cyclase-activating polypeptide receptor activity small GTPase binding vasoactive intestinal polypeptide receptor activity | Rattus norvegicus | Alternative splicing Cell membrane Developmental protein Differentiation Disulfide bond G-protein coupled receptor Glycoprotein Membrane Phosphoprotein Receptor Reference proteome Signal Spermatogenesis Transducer Transmembrane Transmembrane helix | MARVLQLSLT | MARVLQLSLTALLLPVAIAMHSDCIFKKEQAMCLERIQRANDLMGLNESSPGCPGMWDNITCWKPAQVGEMVLVSCPEVFRIFNPDQVWMTETIGDSGFADSNSLEITDMGVVGRNCTEDGWSEPFPHYFDACGFDDYEPESGDQDYYYLSVKALYTVGYSTSLATLTTAMVILCRFRKLHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSSHCFVSTVECKAVMVFFHYCVVSNYFWLFIEGLYLFTLLVETFFPERRYFYWYTIIGWGTPTVCVTVWAVLRLYFDDAGCWDMNDSTALWWVIKGPVVGSIMVNF... | adenylate cyclase-modulating G protein-coupled receptor signaling pathway cAMP-mediated signaling cell differentiation cell surface receptor signaling pathway development of primary female sexual characteristics multicellular organismal response to stress negative regulation of response to reactive oxygen species posit... |
blood vessel diameter maintenance blood vessel remodeling cartilage development involved in endochondral bone morphogenesis cellular response to hypoxia cerebellum morphogenesis cysteine biosynthetic process cysteine biosynthetic process from serine cysteine biosynthetic process via cystathionine DNA protection endocho... | cytoplasm; cytosol; nucleus | carbon monoxide binding cystathionine beta-synthase activity enzyme binding heme binding identical protein binding metal ion binding modified amino acid binding nitric oxide binding nitrite reductase (NO-forming) activity oxygen binding protein homodimerization activity pyridoxal phosphate binding S-adenosyl-L-methioni... | Rattus norvegicus | Alternative splicing Amino-acid biosynthesis CBS domain Cysteine biosynthesis Cytoplasm Direct protein sequencing Heme Iron Isopeptide bond Lyase Metal-binding Nucleus Phosphoprotein Pyridoxal phosphate Reference proteome Ubl conjugation | MPSGTSQCED | MPSGTSQCEDGSAGCPQDLEVQPEKGQLEKGASGDKERVWISPDTPSRCTWQLGRPMADSPHYHTVPTKSPKILPDILRKIGNTPMVRINRISKNAGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERAGTLKPGDTIIEPTSGNTGIGLALAAAVKGYRCIIVMPEKMSMEKVDVLRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDDTAEEILQQCDGKVDMLVASAGTGGTITGIARKLKEKCPGCKIIGVDPEGSILAEPEELNQTEQTAYEVEGIGYDFIPTVLDRAVVDRW... | blood vessel diameter maintenance blood vessel remodeling cartilage development involved in endochondral bone morphogenesis cellular response to hypoxia cerebellum morphogenesis cysteine biosynthetic process cysteine biosynthetic process from serine cysteine biosynthetic process via cystathionine DNA protection endocho... |
cytoplasmic translation positive regulation of microtubule polymerization regulation of mitotic spindle assembly | cytoplasm; cytosol; nuclear body; nucleoplasm; nucleus; polysome | GTP binding GTPase activity identical protein binding microtubule binding potassium ion binding | Mus musculus | Acetylation Cytoplasm GTP-binding Hydrolase Hydroxylation Magnesium Metal-binding Nucleotide-binding Nucleus Phosphoprotein Reference proteome Ubl conjugation | MSGTLAKIAE | MSGTLAKIAEIEAEMARTQKNKATAHHLGLLKARLAKLRRELITPKGGGGGGPGEGFDVAKTGDARIGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQLLDLPGIIEGAKDGKGRGRQVIAVARTCNLILIVLDVLKPLGHKKIIENELEGFGIRLNSKPPNIGFKKKDKGGINLTATCPQSELDAETVKSILAEYKIHNADVTLRSDATADDLIDVVEGNRVYIPCIYVLNKIDQISIEELDIIYKVPHCVPISAHHRWNFDDLLEKIWDYLKLVRIYTKPKGQLPDYTSPVVLPYSRTTVED... | cytoplasmic translation positive regulation of microtubule polymerization regulation of mitotic spindle assembly cytoplasm; cytosol; nuclear body; nucleoplasm; nucleus; polysome GTP binding GTPase activity identical protein binding microtubule binding potassium ion binding Mus musculus Acetylation Cytoplasm GTP-binding... |
axonogenesis cellular response to hormone stimulus cholecystokinin signaling pathway forebrain development G protein-coupled receptor signaling pathway neuron migration phospholipase C-activating G protein-coupled receptor signaling pathway regulation of hormone secretion | cytosol; membrane; nucleoplasm; plasma membrane | cholecystokinin receptor activity peptide binding peptide hormone binding | Homo sapiens | 3D-structure Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MDVVDSLLVN | MDVVDSLLVNGSNITPPCELGLENETLFCLDQPRPSKEWQPAVQILLYSLIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICKPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYSNLVPFTKNNNQTANMCRFLLPNDVMQQSWHTFLLLILFLIPGIVMMVAYGLISLELYQGIKFEASQKKSAKERKPSTTSSGKYEDSDGCYLQKTRPPRKLELRQLSTGSSSRANRIRSNSSAANLMAKKRVIRMLIVIVV... | axonogenesis cellular response to hormone stimulus cholecystokinin signaling pathway forebrain development G protein-coupled receptor signaling pathway neuron migration phospholipase C-activating G protein-coupled receptor signaling pathway regulation of hormone secretion cytosol; membrane; nucleoplasm; plasma membrane... |
cell surface receptor signaling pathway cholecystokinin signaling pathway digestive tract development gastric acid secretion gland development pH reduction phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of cell population proliferation positive regulation of cytosolic calciu... | intracellular membrane-bounded organelle; plasma membrane | 1-phosphatidylinositol-3-kinase regulator activity cholecystokinin receptor activity gastrin receptor activity peptide hormone binding type B gastrin/cholecystokinin receptor binding | Homo sapiens | 3D-structure Alternative splicing Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MELLKLNRSV | MELLKLNRSVQGTGPGPGASLCRPGAPLLNSSSVGNLSCEPPRIRGAGTRELELAIRITLYAVIFLMSVGGNMLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTFIFGTVICKAVSYLMGVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVIVATWLLSGLLMVPYPVYTVVQPVGPRVLQCVHRWPSARVRQTWSVLLLLLLFFIPGVVMAVAYGLISRELYLGLRFDGDSDSDSQSRVRNQGGLPGAVHQNGRCRPETGAVGEDSDGCYVQLPRSRPALELTALTAPGPGSGSRP... | cell surface receptor signaling pathway cholecystokinin signaling pathway digestive tract development gastric acid secretion gland development pH reduction phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of cell population proliferation positive regulation of cytosolic calciu... |
adenylate cyclase-modulating G protein-coupled receptor signaling pathway cell surface receptor signaling pathway G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger positive regulation of cell population proliferation | plasma membrane; receptor complex | G protein-coupled peptide receptor activity peptide hormone binding vasoactive intestinal polypeptide receptor activity | Homo sapiens | 3D-structure Alternative splicing Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Membrane Receptor Reference proteome Signal Transducer Transmembrane Transmembrane helix | MRPPSPLPAR | MRPPSPLPARWLCVLAGALAWALGPAGGQAARLQEECDYVQMIEVQHKQCLEEAQLENETIGCSKMWDNLTCWPATPRGQVVVLACPLIFKLFSSIQGRNVSRSCTDEGWTHLEPGPYPIACGLDDKAASLDEQQTMFYGSVKTGYTIGYGLSLATLLVATAILSLFRKLHCTRNYIHMHLFISFILRAAAVFIKDLALFDSGESDQCSEGSVGCKAAMVFFQYCVMANFFWLLVEGLYLYTLLAVSFFSERKYFWGYILIGWGVPSTFTMVWTIARIHFEDYGCWDTINSSLWWIIKGPILTSILVNFILFICIIRILL... | adenylate cyclase-modulating G protein-coupled receptor signaling pathway cell surface receptor signaling pathway G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger positive regulation of cell population proliferation plasma membrane;... |
anterior/posterior pattern specification diencephalon morphogenesis inner ear morphogenesis metencephalon development midbrain development positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II | chromatin; nucleus | DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding | Homo sapiens | Developmental protein DNA-binding Homeobox Isopeptide bond Nucleus Reference proteome Ubl conjugation | MMSYLKQPPY | MMSYLKQPPYGMNGLGLAGPAMDLLHPSVGYPATPRKQRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQSGSGTKSRPAKKKSSPVRESSGSESSGQFTPPAVSSSASSSSSASSSSANPAAAAAAGLGGNPVAAASSLSTPAASSIWSPASISPGSAPASVSVPEPLAAPSNTSCMQRSVAAGAATAAASYPMSYGQGGSYGQGYPTPSSSYFGGVDCSSYLAPMHSHHHPHQLSPMAPSSMAGHHHHHPHAHHPLSQSSGHHHHHHHHHHQGYGGSGLAFNSADCLDYK... | anterior/posterior pattern specification diencephalon morphogenesis inner ear morphogenesis metencephalon development midbrain development positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II chromatin; nucleus DNA-binding transcription activator activity, RNA polym... |
axon guidance dopaminergic neuron differentiation forebrain development midbrain development positive regulation of DNA-templated transcription positive regulation of embryonic development positive regulation of gastrulation positive regulation of transcription by RNA polymerase II primitive streak formation protein-co... | chromatin; growth cone; nucleus; protein-containing complex | DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific eukaryotic initiation factor 4E binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding | Homo sapiens | Alternative splicing Developmental protein Disease variant DNA-binding Homeobox Microphthalmia Nucleus Reference proteome | MMSYLKQPPY | MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYPATPRKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAKKKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPASISPLSDPLSTSSSCMQRSYPMTYTQASGYSQGYAGSTSYFGGMDCGSYLTPMHHQLPGPGATLSPMGTNAVTSHLNQSPASLSTQGYGASSLGFNSTTDCLDYKDQTASWKLNFNADCLDYKDQTSSWKFQVL | axon guidance dopaminergic neuron differentiation forebrain development midbrain development positive regulation of DNA-templated transcription positive regulation of embryonic development positive regulation of gastrulation positive regulation of transcription by RNA polymerase II primitive streak formation protein-co... |
adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway circadian regulation of gene expression homoiothermy locomotor rhythm regulation of blood pressure regulation of feeding behavior regulation of heart rate regulation of met... | cytoplasm; plasma membrane | melanocortin receptor activity melanocyte-stimulating hormone receptor activity neuropeptide binding peptide hormone binding | Rattus norvegicus | Biological rhythms Cell membrane G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MNSSCCPSSS | MNSSCCPSSSYPTLPNLSQHPAAPSASNRSGSGFCEQVFIKPEVFLALGIVSLMENILVILAVVRNGNLHSPMYFFLCSLAAADMLVSLSNSLETIMIVVINSDSLTLEDQFIQHMDNIFDSMICISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALSLIVAIWVCCGICGVMFIVYSESKMVIVCLITMFFAMVLLMGTLYIHMFLFARLHVQRIAALPPADGVAPQQHSCMKGAVTITILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSLELRNTFKEILCGCNGM... | adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway circadian regulation of gene expression homoiothermy locomotor rhythm regulation of blood pressure regulation of feeding behavior regulation of heart rate regulation of met... |
adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway diet induced thermogenesis energy reserve metabolic process feeding behavior insulin secretion negative regulation of feeding behavior positive regulation of bone resorptio... | cytoplasm; membrane; plasma membrane | melanocortin receptor activity melanocyte-stimulating hormone receptor activity neuropeptide binding peptide hormone binding ubiquitin protein ligase binding | Homo sapiens | 3D-structure Cell membrane Disease variant Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Obesity Palmitate Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MVNSTHRGMH | MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCY... | adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway diet induced thermogenesis energy reserve metabolic process feeding behavior insulin secretion negative regulation of feeding behavior positive regulation of bone resorptio... |
calcium ion transport calcium-mediated signaling cell adhesion cell chemotaxis cell surface receptor signaling pathway cell-cell signaling chemokine-mediated signaling pathway chemotaxis cytokine-mediated signaling pathway dendritic cell chemotaxis exocytosis G protein-coupled receptor signaling pathway, coupled to cyc... | cytoplasm; external side of plasma membrane; plasma membrane | C-C chemokine binding C-C chemokine receptor activity chemokine (C-C motif) ligand 5 binding chemokine (C-C motif) ligand 7 binding chemokine receptor activity phosphatidylinositol phospholipase C activity | Homo sapiens | 3D-structure Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Membrane Receptor Reference proteome Transducer Transmembrane Transmembrane helix | METPNTTEDY | METPNTTEDYDTTTEFDYGDATPCQKVNERAFGAQLLPPLYSLVFVIGLVGNILVVLVLVQYKRLKNMTSIYLLNLAISDLLFLFTLPFWIDYKLKDDWVFGDAMCKILSGFYYTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIIIWALAILASMPGLYFSKTQWEFTHHTCSLHFPHESLREWKLFQALKLNLFGLVLPLLVMIICYTGIIKILLRRPNEKKSKAVRLIFVIMIIFFLFWTPYNLTILISVFQDFLFTHECEQSRHLDLAVQVTEVIAYTHCCVNPVIYAFVGERFRKYLRQLFHRRV... | calcium ion transport calcium-mediated signaling cell adhesion cell chemotaxis cell surface receptor signaling pathway cell-cell signaling chemokine-mediated signaling pathway chemotaxis cytokine-mediated signaling pathway dendritic cell chemotaxis exocytosis G protein-coupled receptor signaling pathway, coupled to cyc... |
adult feeding behavior G protein-coupled receptor signaling pathway glucose metabolic process regulation of blood pressure | membrane; plasma membrane | bombesin receptor activity neuropeptide receptor activity | Homo sapiens | Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MAQRQPHSPN | MAQRQPHSPNQTLISITNDTESSSSVVSNDNTNKGWSGDNSPGIEALCAIYITYAVIISVGILGNAILIKVFFKTKSMQTVPNIFITSLAFGDLLLLLTCVPVDATHYLAEGWLFGRIGCKVLSFIRLTSVGVSVFTLTILSADRYKAVVKPLERQPSNAILKTCVKAGCVWIVSMIFALPEAIFSNVYTFRDPNKNMTFESCTSYPVSKKLLQEIHSLLCFLVFYIIPLSIISVYYSLIARTLYKSTLNIPTEEQSHARKQIESRKRIARTVLVLVALFALCWLPNHLLYLYHSFTSQTYVDPSAMHFIFTIFSRVLAF... | adult feeding behavior G protein-coupled receptor signaling pathway glucose metabolic process regulation of blood pressure membrane; plasma membrane bombesin receptor activity neuropeptide receptor activity Homo sapiens Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate ... |
adaptive immune response B cell activation involved in immune response dendritic cell chemotaxis dendritic cell homeostasis G protein-coupled receptor signaling pathway humoral immune response immune response leukocyte chemotaxis mature B cell differentiation involved in immune response osteoclast differentiation posit... | plasma membrane | G protein-coupled receptor activity oxysterol binding | Homo sapiens | 3D-structure Adaptive immunity Cell membrane Disulfide bond G-protein coupled receptor Immunity Membrane Phosphoprotein Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MDIQMANNFT | MDIQMANNFTPPSATPQGNDCDLYAHHSTARIVMPLHYSLVFIIGLVGNLLALVVIVQNRKKINSTTLYSTNLVISDILFTTALPTRIAYYAMGFDWRIGDALCRITALVFYINTYAGVNFMTCLSIDRFIAVVHPLRYNKIKRIEHAKGVCIFVWILVFAQTLPLLINPMSKQEAERITCMEYPNFEETKSLPWILLGACFIGYVLPLIIILICYSQICCKLFRTAKQNPLTEKSGVNKKALNTIILIIVVFVLCFTPYHVAIIQHMIKKLRFSNFLECSQRHSFQISLHFTVCLMNFNCCMDPFIYFFACKGYKRKVM... | adaptive immune response B cell activation involved in immune response dendritic cell chemotaxis dendritic cell homeostasis G protein-coupled receptor signaling pathway humoral immune response immune response leukocyte chemotaxis mature B cell differentiation involved in immune response osteoclast differentiation posit... |
cortical actin cytoskeleton organization mitotic cytokinesis negative regulation of cytokinesis negative regulation of endocytosis positive regulation of phagocytosis, engulfment Ras protein signal transduction regulation of cell cycle regulation of cell population proliferation regulation of myosin II filament assembl... | cell cortex; cytoplasmic side of plasma membrane; lipid droplet; macropinosome; nuclear matrix; phagocytic vesicle; plasma membrane | G protein activity GDP binding GTP binding GTPase activity | Dictyostelium discoideum | Cell membrane GTP-binding Hydrolase Lipoprotein Membrane Methylation Nucleotide-binding Prenylation Reference proteome | MSVSNEYKLV | MSVSNEYKLVVMGGGGVGKSALTIQFIQNHFIEEYDPTIEDSYRRQCQVDEDTCLLDILDTAGQDDYSAMRDQYMRTGQGFLCVYDVTSRTSFEEINVVREQIIRVKDNDKVPIVLVGNKCDLENLREVTEGEGSELAKSFSVPFLETSAKKRLNVDECFFEVVREIKKSLKEPGRSKKDKKGGILKKFKGGDCLIL | cortical actin cytoskeleton organization mitotic cytokinesis negative regulation of cytokinesis negative regulation of endocytosis positive regulation of phagocytosis, engulfment Ras protein signal transduction regulation of cell cycle regulation of cell population proliferation regulation of myosin II filament assembl... |
actin filament organization cell morphogenesis cell motility cortical actin cytoskeleton organization macropinocytosis negative regulation of cell migration negative regulation of cell motility pinocytosis positive regulation of endocytosis positive regulation of macropinocytosis positive regulation of phagocytosis Ras... | plasma membrane | G protein activity GDP binding GTP binding GTPase activity phosphatidylinositol 3-kinase binding | Dictyostelium discoideum | Cell membrane GTP-binding Hydrolase Lipoprotein Membrane Methylation Nucleotide-binding Prenylation Reference proteome | MFNFKLVLVG | MFNFKLVLVGPGGVGKSCLTIQFIAQKFVDEYDPTLEDSYRKQTTVDGEECLLDIYDTAGQEDFSAVRDQYMRTGEGFLCVYSITYLQSFKEIHRLHNHLLKVKDLDSVPFVLVGNKCDLNEYREVSTAEGEELAKKLNCKFLETSAKERINVSESFYELVREVKKARQSNQHSNSQEQNTDQPIKKKKSCNLL | actin filament organization cell morphogenesis cell motility cortical actin cytoskeleton organization macropinocytosis negative regulation of cell migration negative regulation of cell motility pinocytosis positive regulation of endocytosis positive regulation of macropinocytosis positive regulation of phagocytosis Ras... |
chromosome segregation microtubule cytoskeleton organization mitotic cell cycle | centrosome; cytoplasm; cytoskeleton; microtubule; phagocytic vesicle | GTP binding hydrolase activity metal ion binding structural constituent of cytoskeleton | Dictyostelium discoideum | Cytoplasm Cytoskeleton GTP-binding Hydrolase Magnesium Metal-binding Microtubule Nucleotide-binding Reference proteome | MGREIISIHI | MGREIISIHIGQAGVQVGNSCWELYCLEHGIERDGSIPADRKQSSDVNNLNKDLGTFFSESTNGKKVVPRAIFLDLEPTVIDEIRTGDYKNLFHPEQLITGKEDAANNYARGHYTVGKELIDVCVDRIRRLADQCDGLQGFLVFHSVGGGTGSGFGSLLLQKLALDYGGKKSKLDFCVYPSPQVSTSVVEPYNSVLSTHSLLEHTDVSFMLDNEAIYNICKNSLDIEKPTYTNLNRLIAQVISSLTSSLRFPGQLNLDINDIQTNLVPFPRLHFVLCSYAPVISREKAHHETITVDNITSAVFSEKNIMAKCQPNLGKYM... | chromosome segregation microtubule cytoskeleton organization mitotic cell cycle centrosome; cytoplasm; cytoskeleton; microtubule; phagocytic vesicle GTP binding hydrolase activity metal ion binding structural constituent of cytoskeleton Dictyostelium discoideum Cytoplasm Cytoskeleton GTP-binding Hydrolase Magnesium Met... |
microtubule cytoskeleton organization mitotic cell cycle response to bacterium | centrosome; cytoplasm; cytoskeleton; microtubule; phagocytic vesicle | GTP binding GTPase activity metal ion binding structural constituent of cytoskeleton | Dictyostelium discoideum | Cytoplasm Cytoskeleton GTP-binding Magnesium Metal-binding Microtubule Nucleotide-binding Reference proteome | MREIVQIQAG | MREIVQIQAGQCGNQIGSKFWEVISEEHGIQSDGFHAGGEDEHLKRLQLERINVYYNEARDGKYVPRSVLVDLEPGTVDTIKASPYGKLFRPDNFIHGQSGAGNNWAKGHYTEGVELVESVLDVVRRETEGCDCLQGFQVTHSIGGGTGSGLGTLLISKIREEFPDRMMCTFSVVPSPKVSLTVVEPYNATLSVHQLVENADEVMCIDNEALHDICFRTLKLTQPNYGDLNHLISSVMSGITCCLRFPGQLNSDLRKLAVNLIPFPRLHFFLVGFAPLTAKGASSYNRITVPELTQQMFDAKNMMAASDPHNGKYLTASA... | microtubule cytoskeleton organization mitotic cell cycle response to bacterium centrosome; cytoplasm; cytoskeleton; microtubule; phagocytic vesicle GTP binding GTPase activity metal ion binding structural constituent of cytoskeleton Dictyostelium discoideum Cytoplasm Cytoskeleton GTP-binding Magnesium Metal-binding Mic... |
negative regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription elongation by RNA polymerase II positive regulation of transcription initiation by RNA polymerase II regulation of establishment of protein localization to chromosome ... | core mediator complex; mediator complex; nucleus | RNA polymerase II-specific DNA-binding transcription factor binding | Saccharomyces cerevisiae | 3D-structure Activator Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MMLGEHLMSW | MMLGEHLMSWSKTGIIAYSDSQSSNANICLTFLESINGINWRFHTPQKYVLHPQLHEVQYQESSSTLSTHSTTTSVNGSTTAGVGSTPNFGGNSNKSPPQFFYNISSIHWNNWFSLPGDMLAVCDELGNMTMLITGQRPDRATTYEKLTMVFQDNVYKIYNHVMPLKPVDKLKPMNIERKQTRKEYNTSILEFRWLTSSKSVIVSQFCAFDSSSNTYRSRAQQVPPYGVYHPPFIKYACLAIRKNGQIDFWYQFSNSKDHKKITLQLLDTSNQRFKDLQWLEFARITPMNDDQCMLITTYSKLSKNISFYKLHVNWNLNA... | negative regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription elongation by RNA polymerase II positive regulation of transcription initiation by RNA polymerase II regulation of establishment of protein localization to chromosome ... |
cysteine biosynthetic process from serine | chloroplast stroma; chromoplast | cysteine synthase activity | Spinacia oleracea | Amino-acid biosynthesis Chloroplast Chromoplast Cysteine biosynthesis Direct protein sequencing Plastid Pyridoxal phosphate Reference proteome Transferase Transit peptide | MASLVNNAYA | MASLVNNAYAALRTSKLELREVKNLANFRVGPPSSLSCNNFKKVSSSPITCKAVSLSPPSTIEGLNIAEDVSQLIGKTPMVYLNNVSKGSVANIAAKLESMEPCCSVKDRIGYSMIDDAEQKGVITPGKTTLVEPTSGNTGIGLAFIAAARGYKITLTMPASMSMERRVILKAFGAELVLTDPAKGMKGAVEKAEEILKKTPDSYMLQQFDNPANPKIHYETTGPEIWEDTKGKVDIFVAGIGTGGTISGVGRYLKERNPGVQVIGIEPTESNILSGGKPGPHKIQGLGAGFVPSNLDLGVMDEVIEVSSEEAVEMAKQL... | cysteine biosynthetic process from serine chloroplast stroma; chromoplast cysteine synthase activity Spinacia oleracea Amino-acid biosynthesis Chloroplast Chromoplast Cysteine biosynthesis Direct protein sequencing Plastid Pyridoxal phosphate Reference proteome Transferase Transit peptide MASLVNNAYA MASLVNNAYAALRTSKLEL... |
blood coagulation regulation of blood coagulation response to nutrient | collagen-containing extracellular matrix; extracellular space | heparin binding identical protein binding protease binding serine-type endopeptidase inhibitor activity | Mus musculus | Blood coagulation Disulfide bond Glycoprotein Hemostasis Heparin-binding Phosphoprotein Protease inhibitor Reference proteome Secreted Serine protease inhibitor Signal | MYSPGAGSGA | MYSPGAGSGAAGERKLCLLSLLLIGALGCAICHGNPVDDICIAKPRDIPVNPLCIYRSPGKKATEEDGSEQKVPEATNRRVWELSKANSRFATNFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLKQLMEVFKFDTISEKTSDQIHFFFAKLNCRLYRKANKSSDLVSANRLFGDKSLTFNESYQDVSEVVYGAKLQPLDFKENPEQSRVTINNWVANKTEGRIKDVIPQGAINELTALVLVNTIYFKGLWKSKFSPENTRKEPFYKVDGQSCPVPMMYQEGKFKYRRVAEGTQVLELPFKGDDITMVLILPK... | blood coagulation regulation of blood coagulation response to nutrient collagen-containing extracellular matrix; extracellular space heparin binding identical protein binding protease binding serine-type endopeptidase inhibitor activity Mus musculus Blood coagulation Disulfide bond Glycoprotein Hemostasis Heparin-bindi... |
heme transport mitochondrial fusion mitochondrial genome maintenance mitochondrial inner membrane fusion mitochondrial membrane organization mitochondrial outer membrane fusion mitochondrion inheritance mitochondrion organization | cytoplasm; membrane; microtubule; mitochondrial crista; mitochondrial inner boundary membrane; mitochondrial inner membrane; mitochondrial intermembrane space; mitochondrion | cardiolipin binding GTP binding GTPase activity microtubule binding phosphatidic acid binding phosphatidylinositol-3,5-bisphosphate binding phosphatidylserine binding | Saccharomyces cerevisiae | 3D-structure Direct protein sequencing GTP-binding Hydrolase Membrane Mitochondrion Mitochondrion inner membrane Nucleotide-binding Reference proteome Signal-anchor Transit peptide Transmembrane Transmembrane helix | MNASPVRLLI | MNASPVRLLILRRQLATHPAILYSSPYIKSPLVHLHSRMSNVHRSAHANALSFVITRRSISHFPKIISKIIRLPIYVGGGMAAAGSYIAYKMEEASSFTKDKLDRIKDLGESMKEKFNKMFSGDKSQDGGHGNDGTVPTATLIAATSLDDDESKRQGDPKDDDDEDDDDEDDENDSVDTTQDEMLNLTKQMIEIRTILNKVDSSSAHLTLPSIVVIGSQSSGKSSVLESIVGREFLPKGSNMVTRRPIELTLVNTPNSNNVTADFPSMRLYNIKDFKEVKRMLMELNMAVPTSEAVSEEPIQLTIKSSRVPDLSLVDLPG... | heme transport mitochondrial fusion mitochondrial genome maintenance mitochondrial inner membrane fusion mitochondrial membrane organization mitochondrial outer membrane fusion mitochondrion inheritance mitochondrion organization cytoplasm; membrane; microtubule; mitochondrial crista; mitochondrial inner boundary membr... |
glutamine biosynthetic process | cytoplasm; nuclear periphery; nucleus | ATP binding glutamine synthetase activity | Saccharomyces cerevisiae | 3D-structure Acetylation ATP-binding Cytoplasm Direct protein sequencing Isopeptide bond Ligase Nucleotide-binding Phosphoprotein Reference proteome Ubl conjugation | MAEASIEKTQ | MAEASIEKTQILQKYLELDQRGRIIAEYVWIDGTGNLRSKGRTLKKRITSIDQLPEWNFDGSSTNQAPGHDSDIYLKPVAYYPDPFRRGDNIVVLAACYNNDGTPNKFNHRHEAAKLFAAHKDEEIWFGLEQEYTLFDMYDDVYGWPKGGYPAPQGPYYCGVGAGKVYARDMIEAHYRACLYAGLEISGINAEVMPSQWEFQVGPCTGIDMGDQLWMARYFLHRVAEEFGIKISFHPKPLKGDWNGAGCHTNVSTKEMRQPGGMKYIEQAIEKLSKRHAEHIKLYGSDNDMRLTGRHETASMTAFSSGVANRGSSIRIPR... | glutamine biosynthetic process cytoplasm; nuclear periphery; nucleus ATP binding glutamine synthetase activity Saccharomyces cerevisiae 3D-structure Acetylation ATP-binding Cytoplasm Direct protein sequencing Isopeptide bond Ligase Nucleotide-binding Phosphoprotein Reference proteome Ubl conjugation MAEASIEKTQ MAEASIE... |
acetylcholine receptor signaling pathway activation of transmembrane receptor protein tyrosine kinase activity behavioral response to nicotine excitatory postsynaptic potential locomotory behavior monoatomic ion transport nervous system development regulation of acetylcholine secretion, neurotransmission regulation of ... | acetylcholine-gated channel complex; dendrite; endoplasmic reticulum; Golgi apparatus; membrane; neuron projection; neuronal cell body; nuclear speck; plasma membrane; plasma membrane raft; postsynaptic density; postsynaptic membrane; synapse | acetylcholine binding acetylcholine receptor activity acetylcholine-gated monoatomic cation-selective channel activity ligand-gated monoatomic ion channel activity | Homo sapiens | 3D-structure Alternative splicing Cell membrane Disease variant Disulfide bond Endoplasmic reticulum Glycoprotein Golgi apparatus Ion channel Ion transport Ligand-gated ion channel Membrane Phosphoprotein Postsynaptic cell membrane Receptor Reference proteome Signal Synapse Transmembrane Transmembrane helix Transport U... | MGSGPLSLPL | MGSGPLSLPLALSPPRLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDPVIIHFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGEWAIIKAPGYKHDIKYNCCEEIYPDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIV... | acetylcholine receptor signaling pathway activation of transmembrane receptor protein tyrosine kinase activity behavioral response to nicotine excitatory postsynaptic potential locomotory behavior monoatomic ion transport nervous system development regulation of acetylcholine secretion, neurotransmission regulation of ... |
phosphorylation receptor internalization regulation of G protein-coupled receptor signaling pathway regulation of rhodopsin mediated signaling pathway regulation of signal transduction signal transduction | cell cortex; cytoplasm; cytosol; photoreceptor disc membrane; plasma membrane | ATP binding protein kinase activity rhodopsin kinase activity | Homo sapiens | 3D-structure Acetylation Alternative splicing ATP-binding Cytoplasm Kinase Lipoprotein Nucleotide-binding Palmitate Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MELENIVANS | MELENIVANSLLLKARQGGYGKKSGRSKKWKEILTLPPVSQCSELRHSIEKDYSSLCDKQPIGRRLFRQFCDTKPTLKRHIEFLDAVAEYEVADDEDRSDCGLSILDRFFNDKLAAPLPEIPPDVVTECRLGLKEENPSKKAFEECTRVAHNYLRGEPFEEYQESSYFSQFLQWKWLERQPVTKNTFRHYRVLGKGGFGEVCACQVRATGKMYACKKLQKKRIKKRKGEAMALNEKRILEKVQSRFVVSLAYAYETKDALCLVLTIMNGGDLKFHIYNLGNPGFDEQRAVFYAAELCCGLEDLQRERIVYRDLKPENILL... | phosphorylation receptor internalization regulation of G protein-coupled receptor signaling pathway regulation of rhodopsin mediated signaling pathway regulation of signal transduction signal transduction cell cortex; cytoplasm; cytosol; photoreceptor disc membrane; plasma membrane ATP binding protein kinase activity r... |
acute inflammatory response to antigenic stimulus arachidonic acid secretion G protein-coupled receptor signaling pathway intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator maintenance of blood-brain barrier negative regulation of blood pressure negative regulation of cell populat... | endosome; Golgi apparatus; intracellular membrane-bounded organelle; plasma membrane | beta-2 adrenergic receptor binding bradykinin receptor activity protease binding protein heterodimerization activity type 1 angiotensin receptor binding | Mus musculus | Alternative splicing Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Phosphoprotein Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MPCSWKLLGF | MPCSWKLLGFLSVHEPMPTAASFGIEMFNVTTQVLGSALNGTLSKDNCPDTEWWSWLNAIQAPFLWVLFLLAALENLFVLSVFFLHKNSCTVAEIYLGNLAAADLILACGLPFWAITIANNFDWVFGEVLCRVVNTMIYMNLYSSICFLMLVSIDRYLALVKTMSMGRMRGVRWAKLYSLVIWGCTLLLSSPMLVFRTMREYSEEGHNVTACVIVYPSRSWEVFTNVLLNLVGFLLPLSVITFCTVRILQVLRNNEMKKFKEVQTERKATVLVLAVLGLFVLCWVPFQISTFLDTLLRLGVLSGCWDEHAVDVITQISSY... | acute inflammatory response to antigenic stimulus arachidonic acid secretion G protein-coupled receptor signaling pathway intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator maintenance of blood-brain barrier negative regulation of blood pressure negative regulation of cell populat... |
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway adult locomotory behavior cellular response to growth factor stimulus cellular response to hypoxia cellular response to toxic substance eating behavior G protein-coupled opioid receptor signaling pathway G protein-coupled receptor signaling pathw... | axon terminus; dendrite membrane; membrane; neuron projection; neuronal dense core vesicle; plasma membrane; postsynaptic density membrane; postsynaptic membrane; presynaptic membrane; spine apparatus; synaptic vesicle membrane; vesicle | G protein-coupled enkephalin receptor activity G protein-coupled opioid receptor activity neuropeptide binding receptor serine/threonine kinase binding | Mus musculus | 3D-structure Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Receptor Reference proteome Transducer Transmembrane Transmembrane helix Ubl conjugation | MELVPSARAE | MELVPSARAELQSSPLVNLSDAFPSAFPSAGANASGSPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTQPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAALHLCIALGYANSSLNPVLYAF... | adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway adult locomotory behavior cellular response to growth factor stimulus cellular response to hypoxia cellular response to toxic substance eating behavior G protein-coupled opioid receptor signaling pathway G protein-coupled receptor signaling pathw... |
adenylate cyclase-activating G protein-coupled receptor signaling pathway associative learning cAMP-mediated signaling cell surface receptor signaling pathway feeding behavior hormone secretion insulin secretion learning or memory memory negative regulation of apoptotic process negative regulation of blood pressure neg... | plasma membrane | G protein-coupled peptide receptor activity G protein-coupled receptor activity glucagon receptor activity glucagon-like peptide 1 receptor activity peptide hormone binding peptide receptor activity | Rattus norvegicus | ADP-ribosylation Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Membrane Receptor Reference proteome Signal Transducer Transmembrane Transmembrane helix | MAVTPSLLRL | MAVTPSLLRLALLLLGAVGRAGPRPQGATVSLSETVQKWREYRHQCQRFLTEAPLLATGLFCNRTFDDYACWPDGPPGSFVNVSCPWYLPWASSVLQGHVYRFCTAEGIWLHKDNSSLPWRDLSECEESKQGERNSPEEQLLSLYIIYTVGYALSFSALVIASAILVSFRHLHCTRNYIHLNLFASFILRALSVFIKDAALKWMYSTAAQQHQWDGLLSYQDSLGCRLVFLLMQYCVAANYYWLLVEGVYLYTLLAFSVFSEQRIFKLYLSIGWGVPLLFVIPWGIVKYLYEDEGCWTRNSNMNYWLIIRLPILFAIGVN... | adenylate cyclase-activating G protein-coupled receptor signaling pathway associative learning cAMP-mediated signaling cell surface receptor signaling pathway feeding behavior hormone secretion insulin secretion learning or memory memory negative regulation of apoptotic process negative regulation of blood pressure neg... |
B cell activation calcium-mediated signaling cell chemotaxis G protein-coupled receptor signaling pathway immune response leukocyte chemotaxis lymph node development positive regulation of cytokinesis positive regulation of cytosolic calcium ion concentration | external side of plasma membrane; plasma membrane | C-C chemokine binding C-C chemokine receptor activity C-X-C chemokine receptor activity G protein-coupled receptor activity | Homo sapiens | Alternative splicing B-cell activation Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Membrane Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MNYPLTLEMD | MNYPLTLEMDLENLEDLFWELDRLDNYNDTSLVENHLCPATEGPLMASFKAVFVPVAYSLIFLLGVIGNVLVLVILERHRQTRSSTETFLFHLAVADLLLVFILPFAVAEGSVGWVLGTFLCKTVIALHKVNFYCSSLLLACIAVDRYLAIVHAVHAYRHRRLLSIHITCGTIWLVGFLLALPEILFAKVSQGHHNNSLPRCTFSQENQAETHAWFTSRFLYHVAGFLLPMLVMGWCYVGVVHRLRQAQRRPQRQKAVRVAILVTSIFFLCWSPYHIVIFLDTLARLKAVDNTCKLNGSLPVAITMCEFLGLAHCCLNPM... | B cell activation calcium-mediated signaling cell chemotaxis G protein-coupled receptor signaling pathway immune response leukocyte chemotaxis lymph node development positive regulation of cytokinesis positive regulation of cytosolic calcium ion concentration external side of plasma membrane; plasma membrane C-C chemok... |
adenylate cyclase-activating serotonin receptor signaling pathway behavioral response to pain chemical synaptic transmission circadian rhythm detection of mechanical stimulus involved in sensory perception of pain dopaminergic neuron differentiation G protein-coupled receptor signaling pathway, coupled to cyclic nucleo... | axon terminus; dendrite; neuronal cell body; postsynaptic membrane; presynaptic membrane; synaptic vesicle | G protein-coupled serotonin receptor activity neurotransmitter receptor activity | Mus musculus | Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MMDVNSSGRP | MMDVNSSGRPDLYGHLRSLILPEVGRRLQDLSPDGGAHSVVSSWMPHLLSGFPEVTASPAPTWDAPPDNVSGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFSGFPRVQPESVISLNGVVKLQKEVEECANLSRLLKHERKNIS... | adenylate cyclase-activating serotonin receptor signaling pathway behavioral response to pain chemical synaptic transmission circadian rhythm detection of mechanical stimulus involved in sensory perception of pain dopaminergic neuron differentiation G protein-coupled receptor signaling pathway, coupled to cyclic nucleo... |
adenylate cyclase-activating serotonin receptor signaling pathway behavioral response to pain chemical synaptic transmission circadian rhythm detection of mechanical stimulus involved in sensory perception of pain dopaminergic neuron differentiation G protein-coupled receptor signaling pathway, coupled to cyclic nucleo... | axon terminus; dendrite; neuronal cell body; postsynaptic membrane; presynaptic membrane; synaptic vesicle | G protein-coupled serotonin receptor activity neurotransmitter receptor activity | Rattus norvegicus | Alternative splicing Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MMDVNSSGRP | MMDVNSSGRPDLYGHLRSLILPEVGRGLQDLSPDGGAHPVVSSWMPHLLSGFLEVTASPAPTWDAPPDNVSGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVQPESVISLNGVVKLQKEVEECANLSRLLKHERKNIS... | adenylate cyclase-activating serotonin receptor signaling pathway behavioral response to pain chemical synaptic transmission circadian rhythm detection of mechanical stimulus involved in sensory perception of pain dopaminergic neuron differentiation G protein-coupled receptor signaling pathway, coupled to cyclic nucleo... |
absorption of visible light cellular response to light stimulus G protein-coupled receptor signaling pathway phototransduction rhodopsin mediated signaling pathway visual perception | membrane; photoreceptor disc membrane; photoreceptor inner segment membrane; photoreceptor outer segment; photoreceptor outer segment membrane; plasma membrane | 11-cis retinal binding G protein-coupled photoreceptor activity metal ion binding | Canis lupus familiaris | 3D-structure Acetylation Cell projection Chromophore Disease variant Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Metal-binding Palmitate Phosphoprotein Photoreceptor protein Receptor Reference proteome Retinal protein Sensory transduction Transducer Transmembrane Transmembrane helix Visi... | MNGTEGPNFY | MNGTEGPNFYVPFSNKTGVVRSPFEYPQYYLAEPWQFSMLAAYMFLLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNVEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWVMALACAAPPLAGWSRYIPEGMQCSCGIDYYTLKPEINNESFVIYMFVVHFAIPMIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWVPYASVAFYIFTHQGSDFGPIFMTLPAFFAKSSSIYNPVIYIMMNKQFRNCMITT... | absorption of visible light cellular response to light stimulus G protein-coupled receptor signaling pathway phototransduction rhodopsin mediated signaling pathway visual perception membrane; photoreceptor disc membrane; photoreceptor inner segment membrane; photoreceptor outer segment; photoreceptor outer segment memb... |
acetate metabolic process | cytosol; mitochondrion | acetate CoA-transferase activity acetyl-CoA hydrolase activity | Saccharomyces cerevisiae | 3D-structure Acetylation Cytoplasm Direct protein sequencing Glycoprotein Hydrolase Phosphoprotein Reference proteome | MTISNLLKQR | MTISNLLKQRVRYAPYLKKVKEAHELIPLFKNGQYLGWSGFTGVGTPKAVPEALIDHVEKNNLQGKLRFNLFVGASAGPEENRWAEHDMIIKRAPHQVGKPIAKAINQGRIEFFDKHLSMFPQDLTYGFYTRERKDNKILDYTIIEATAIKEDGSIVPGPSVGGSPEFITVSDKVIIEVNTATPSFEGIHDIDMPVNPPFRKPYPYLKVDDKCGVDSIPVDPEKVVAIVESTMRDQVPPNTPSDDMSRAIAGHLVEFFRNEVKHGRLPENLLPLQSGIGNIANAVIEGLAGAQFKHLTVWTEVLQDSFLDLFENGSLDYA... | acetate metabolic process cytosol; mitochondrion acetate CoA-transferase activity acetyl-CoA hydrolase activity Saccharomyces cerevisiae 3D-structure Acetylation Cytoplasm Direct protein sequencing Glycoprotein Hydrolase Phosphoprotein Reference proteome MTISNLLKQR MTISNLLKQRVRYAPYLKKVKEAHELIPLFKNGQYLGWSGFTGVGTPKAVPEA... |
mitochondrial genome maintenance thiamine biosynthetic process thiazole biosynthetic process | cytosol; nucleus | ferrous iron binding pentosyltransferase activity | Saccharomyces cerevisiae | 3D-structure Cytoplasm Direct protein sequencing Iron Metal-binding NAD Nucleus Reference proteome Thiamine biosynthesis Transferase | MSATSTATST | MSATSTATSTSASQLHLNSTPVTHCLSDIVKKEDWSDFKFAPIRESTVSRAMTSRYFKDLDKFAVSDVIIVGAGSSGLSAAYVIAKNRPDLKVCIIESSVAPGGGSWLGGQLFSAMVMRKPAHLFLQELEIPYEDEGDYVVVKHAALFISTVLSKVLQLPNVKLFNATCVEDLVTRPPTEKGEVTVAGVVTNWTLVTQAHGTQCCMDPNVIELAGYKNDGTRDLSQKHGVILSTTGHDGPFGAFCAKRIVDIDQNQKLGGMKGLDMNHAEHDVVIHSGAYAGVDNMYFAGMEVAELDGLNRMGPTFGAMALSGVHAAEQI... | mitochondrial genome maintenance thiamine biosynthetic process thiazole biosynthetic process cytosol; nucleus ferrous iron binding pentosyltransferase activity Saccharomyces cerevisiae 3D-structure Cytoplasm Direct protein sequencing Iron Metal-binding NAD Nucleus Reference proteome Thiamine biosynthesis Transferase M... |
cell surface receptor signaling pathway cellular response to external biotic stimulus cytidine deamination cytosine metabolic process negative regulation of cell growth negative regulation of nucleotide metabolic process pyrimidine-containing compound salvage response to cycloheximide UMP salvage | cytosol; extracellular region; ficolin-1-rich granule lumen; secretory granule lumen; tertiary granule lumen | cytidine deaminase activity deoxycytidine deaminase activity identical protein binding nucleoside binding protein homodimerization activity zinc ion binding | Homo sapiens | 3D-structure Hydrolase Metal-binding Reference proteome Zinc | MAQKRPACTL | MAQKRPACTLKPECVQQLLVCSQEAKKSAYCPYSHFPVGAALLTQEGRIFKGCNIENACYPLGICAERTAIQKAVSEGYKDFRAIAIASDMQDDFISPCGACRQVMREFGTNWPVYMTKPDGTYIVMTVQELLPSSFGPEDLQKTQ | cell surface receptor signaling pathway cellular response to external biotic stimulus cytidine deamination cytosine metabolic process negative regulation of cell growth negative regulation of nucleotide metabolic process pyrimidine-containing compound salvage response to cycloheximide UMP salvage cytosol; extracellular... |
nucleoside salvage nucleotide biosynthetic process pyrimidine nucleotide metabolic process | cytoplasm; cytosol | dCMP deaminase activity deoxyribonucleoside 5'-monophosphate N-glycosidase activity identical protein binding zinc ion binding | Homo sapiens | 3D-structure Allosteric enzyme Alternative splicing Direct protein sequencing Hydrolase Metal-binding Nucleotide biosynthesis Phosphoprotein Reference proteome Zinc | MSEVSCKKRD | MSEVSCKKRDDYLEWPEYFMAVAFLSAQRSKDPNSQVGACIVNSENKIVGIGYNGMPNGCSDDVLPWRRTAENKLDTKYPYVCHAELNAIMNKNSTDVKGCSMYVALFPCNECAKLIIQAGIKEVIFMSDKYHDSDEATAARLLFNMAGVTFRKFIPKCSKIVIDFDSINSRPSQKLQ | nucleoside salvage nucleotide biosynthetic process pyrimidine nucleotide metabolic process cytoplasm; cytosol dCMP deaminase activity deoxyribonucleoside 5'-monophosphate N-glycosidase activity identical protein binding zinc ion binding Homo sapiens 3D-structure Allosteric enzyme Alternative splicing Direct protein seq... |
cellular response to oxidative stress L-proline biosynthetic process negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway proline biosynthetic process regulation of mitochondrial membrane potential | mitochondrial matrix; mitochondrion | identical protein binding pyrroline-5-carboxylate reductase activity | Homo sapiens | 3D-structure Acetylation Alternative splicing Amino-acid biosynthesis Direct protein sequencing Disease variant Mitochondrion NADP Oxidoreductase Phosphoprotein Proline biosynthesis Reference proteome Stress response | MSVGFIGAGQ | MSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSALRKMGVKLTPHNKETVQHSDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLSAFRPAPRVIRCMTNTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCTEVEEDLIDAVTGLSGSGPAYAFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATIHALHVLESGGFRSLLINAVEASCIRTRELQSMADQEQVSPAAIKKTILDKVKLDSPAGTALSPSGHTKLLPRSLAPAGKD | cellular response to oxidative stress L-proline biosynthetic process negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway proline biosynthetic process regulation of mitochondrial membrane potential mitochondrial matrix; mitochondrion identical protein binding pyrroline-5-carboxyl... |
agglutination involved in conjugation with cellular fusion | cell periphery; extracellular region; fungal-type cell wall; side of membrane | cell adhesion molecule binding | Saccharomyces cerevisiae | Cell adhesion Cell wall Disulfide bond Glycoprotein GPI-anchor Lipoprotein Membrane Pheromone response Reference proteome Repeat Secreted Signal | MTLSFAHFTY | MTLSFAHFTYLFTILLGLTNIALASDPETILVTITKTNDANGVVTTTVSPALVSTSTIVQAGTTTLYTTWCPLTVSTSSAAEISPSISYATTLSRFSTLTLSTEVCSHEACPSSSTLPTTTLSVTSKFTSYICPTCHTTAISSLSEVGTTTVVSSSAIEPSSASIISPVTSTLSSTTSSNPTTTSLSSTSTSPSSTSTSPSSTSTSSSSTSTSSSSTSTSSSSTSTSPSSTSTSSSLTSTSSSSTSTSQSSTSTSSSSTSTSPSSTSTSSSSTSTSPSSKSTSASSTSTSSYSTSTSPSLTSSSPTLASTSPSSTSISST... | agglutination involved in conjugation with cellular fusion cell periphery; extracellular region; fungal-type cell wall; side of membrane cell adhesion molecule binding Saccharomyces cerevisiae Cell adhesion Cell wall Disulfide bond Glycoprotein GPI-anchor Lipoprotein Membrane Pheromone response Reference proteome Repe... |
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