row_id string | dataset_id string | source_dataset string | source_file string | source_table string | source_sha string | row_index int64 | split string | subject_type string | entry_id int64 | sequence_id int64 | target_sequence_id int64 | source_sequence_length int64 | target_sequence_length int64 | protein_id int64 | protein_name string | organism string | isoform int64 | protein_ids string | protein_names string | organisms string | isoforms string | uniprot_accessions string | interpro_accessions string | ec_numbers string | megascale_ids string | other_references string | mutations string | substitutions string | deletions string | insertions string | mutation_count int64 | substitution_count int64 | deletion_count int64 | insertion_count int64 | first_position int64 | first_source_aa string | first_target_aa string | conservation float64 | feature_types string | pdb_ids string | afdb_ids string | structure_ids string | structure_methods string | structure_resolution_min float64 | residue_positions string | residue_chain_names string | residue_secondary_structures string | residue_in_pocket_any bool | residue_in_tunnel_any bool | residue_asa_mean float64 | residue_bfactor_mean float64 | experiment_id int64 | experiment_dataset string | ph float64 | measure string | method string | buffer string | buffer_conc string | exp_temperature float64 | ion string | ion_conc string | pdb_chain_mutation string | tm float64 | dtm float64 | dg float64 | dg_text string | ddg float64 | dh float64 | dcp float64 | dhvh float64 | cm float64 | m_value float64 | trypsin_ml float64 | chymotrypsin_ml float64 | stabilizing float64 | stabilizing_text string | domainome_fitness float64 | domainome_fitness_std float64 | domainome_ddg float64 | domainome_ddg_std float64 | reversibility string | state string | measurement_types string | measurement_datasets string | annotation_types string | publication_id string | publication_type string | publication_title string | publication_year int64 | publication_doi string | publication_pmid string | publication_journal string | publication_url string | publication_author_count int64 | publication_authors string | annotations_json string | measurements_json string | features_json string |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
fireprotdb:12950 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,950 | train | mutant | 3,791,072 | 225 | 3,795,017 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G244A | G244A | 1 | 1 | 0 | 0 | 244 | G | A | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,844,308 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.244967 | 0.070203 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9681298,"numValue":0.244967223467299,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9681299,"numValue":0.0702026911954918,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16908,"numValue":4.0,"position":244,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12951 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,951 | train | mutant | 3,791,072 | 225 | 3,795,017 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G244A | G244A | 1 | 1 | 0 | 0 | 244 | G | A | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,113 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.394208 | 1.192882 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182908,"numValue":-0.394208007020279,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182909,"numValue":1.19288205929943,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16908,"numValue":4.0,"position":244,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12952 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,952 | train | mutant | 3,791,073 | 225 | 3,795,018 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G244C | G244C | 1 | 1 | 0 | 0 | 244 | G | C | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,844,309 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.309451 | 0.065459 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9681300,"numValue":0.309450732138746,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9681301,"numValue":0.0654588006439045,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16908,"numValue":4.0,"position":244,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12953 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,953 | train | mutant | 3,791,073 | 225 | 3,795,018 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G244C | G244C | 1 | 1 | 0 | 0 | 244 | G | C | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,114 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.460323 | 0.342179 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182910,"numValue":-0.460322543451777,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182911,"numValue":0.342179017463662,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16908,"numValue":4.0,"position":244,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12954 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,954 | train | mutant | 3,791,074 | 225 | 3,795,019 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G244D | G244D | 1 | 1 | 0 | 0 | 244 | G | D | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,844,310 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.118947 | 0.089767 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9681302,"numValue":0.11894659590761,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9681303,"numValue":0.089766870818754,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16908,"numValue":4.0,"position":244,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12955 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,955 | train | mutant | 3,791,074 | 225 | 3,795,019 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G244D | G244D | 1 | 1 | 0 | 0 | 244 | G | D | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,115 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.21915 | 0.344545 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182912,"numValue":-0.219149794423686,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182913,"numValue":0.344544684038836,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16908,"numValue":4.0,"position":244,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12956 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,956 | train | mutant | 3,791,075 | 225 | 3,795,020 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G244E | G244E | 1 | 1 | 0 | 0 | 244 | G | E | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,844,311 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.156358 | 0.086487 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9681304,"numValue":0.156358440832498,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9681305,"numValue":0.0864873585850552,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16908,"numValue":4.0,"position":244,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12958 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,958 | train | mutant | 3,791,076 | 225 | 3,795,021 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G244F | G244F | 1 | 1 | 0 | 0 | 244 | G | F | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,844,312 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.480028 | 0.191094 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9681306,"numValue":0.480028128954918,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9681307,"numValue":0.19109406459998,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16908,"numValue":4.0,"position":244,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12959 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,959 | train | mutant | 3,791,076 | 225 | 3,795,021 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G244F | G244F | 1 | 1 | 0 | 0 | 244 | G | F | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,117 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182916,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182917,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":16908,"numValue":4.0,"position":244,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12960 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,960 | train | mutant | 3,791,077 | 225 | 3,795,022 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G244H | G244H | 1 | 1 | 0 | 0 | 244 | G | H | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,844,313 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.165451 | 0.086366 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9681308,"numValue":0.165451079643409,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9681309,"numValue":0.0863656099728689,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16908,"numValue":4.0,"position":244,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12961 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,961 | train | mutant | 3,791,077 | 225 | 3,795,022 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G244H | G244H | 1 | 1 | 0 | 0 | 244 | G | H | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,678 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184038,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184039,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":16908,"numValue":4.0,"position":244,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12962 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,962 | train | mutant | 3,791,078 | 225 | 3,795,023 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G244I | G244I | 1 | 1 | 0 | 0 | 244 | G | I | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,844,314 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.993288 | 0.146329 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9681310,"numValue":0.993287685304434,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9681311,"numValue":0.146329287219546,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16908,"numValue":4.0,"position":244,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12963 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,963 | train | mutant | 3,791,078 | 225 | 3,795,023 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G244I | G244I | 1 | 1 | 0 | 0 | 244 | G | I | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,679 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184040,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184041,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":16908,"numValue":4.0,"position":244,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12964 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,964 | train | mutant | 3,791,079 | 225 | 3,795,024 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G244K | G244K | 1 | 1 | 0 | 0 | 244 | G | K | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,844,315 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.198987 | 0.201246 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9681312,"numValue":0.19898653535788,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9681313,"numValue":0.201245750020435,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16908,"numValue":4.0,"position":244,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12965 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,965 | train | mutant | 3,791,079 | 225 | 3,795,024 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G244K | G244K | 1 | 1 | 0 | 0 | 244 | G | K | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,680 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184042,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184043,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":16908,"numValue":4.0,"position":244,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12966 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,966 | train | mutant | 3,791,080 | 225 | 3,795,025 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G244L | G244L | 1 | 1 | 0 | 0 | 244 | G | L | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,844,316 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.483529 | 0.120796 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9681314,"numValue":0.48352860691899,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9681315,"numValue":0.120796478489191,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16908,"numValue":4.0,"position":244,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12967 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,967 | train | mutant | 3,791,080 | 225 | 3,795,025 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G244L | G244L | 1 | 1 | 0 | 0 | 244 | G | L | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,681 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184044,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184045,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":16908,"numValue":4.0,"position":244,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12968 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,968 | train | mutant | 3,791,081 | 225 | 3,795,026 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G244M | G244M | 1 | 1 | 0 | 0 | 244 | G | M | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,844,317 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.222134 | 0.157058 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9681316,"numValue":0.222134255534716,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9681317,"numValue":0.157058016545663,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16908,"numValue":4.0,"position":244,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12969 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,969 | train | mutant | 3,791,081 | 225 | 3,795,026 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G244M | G244M | 1 | 1 | 0 | 0 | 244 | G | M | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,682 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184046,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184047,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":16908,"numValue":4.0,"position":244,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12970 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,970 | train | mutant | 3,791,082 | 225 | 3,795,027 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G244N | G244N | 1 | 1 | 0 | 0 | 244 | G | N | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,844,318 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.000139 | 0.11778 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9681318,"numValue":0.000138915555851709,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9681319,"numValue":0.117780159266684,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16908,"numValue":4.0,"position":244,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12971 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,971 | train | mutant | 3,791,082 | 225 | 3,795,027 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G244N | G244N | 1 | 1 | 0 | 0 | 244 | G | N | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,683 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184048,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184049,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":16908,"numValue":4.0,"position":244,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12972 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,972 | train | mutant | 3,791,083 | 225 | 3,795,028 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G244P | G244P | 1 | 1 | 0 | 0 | 244 | G | P | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,844,319 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.756779 | 0.096734 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9681320,"numValue":0.756779207565094,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9681321,"numValue":0.0967338826567759,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16908,"numValue":4.0,"position":244,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12973 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,973 | train | mutant | 3,791,083 | 225 | 3,795,028 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G244P | G244P | 1 | 1 | 0 | 0 | 244 | G | P | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,684 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184050,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184051,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":16908,"numValue":4.0,"position":244,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12974 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,974 | train | mutant | 3,791,084 | 225 | 3,795,029 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G244Q | G244Q | 1 | 1 | 0 | 0 | 244 | G | Q | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,844,320 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.128314 | 0.098901 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9681322,"numValue":0.12831351061861,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9681323,"numValue":0.0989008580663132,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16908,"numValue":4.0,"position":244,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12975 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,975 | train | mutant | 3,791,084 | 225 | 3,795,029 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G244Q | G244Q | 1 | 1 | 0 | 0 | 244 | G | Q | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,685 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184052,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184053,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":16908,"numValue":4.0,"position":244,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12976 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,976 | train | mutant | 3,791,085 | 225 | 3,795,030 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G244R | G244R | 1 | 1 | 0 | 0 | 244 | G | R | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,844,321 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.312758 | 0.118085 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9681324,"numValue":0.31275847203698,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9681325,"numValue":0.118085058553764,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16908,"numValue":4.0,"position":244,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12977 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,977 | train | mutant | 3,791,085 | 225 | 3,795,030 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G244R | G244R | 1 | 1 | 0 | 0 | 244 | G | R | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,686 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.224663 | 0.271966 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184054,"numValue":-0.224663131916331,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184055,"numValue":0.271965960308991,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16908,"numValue":4.0,"position":244,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12978 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,978 | train | mutant | 3,791,086 | 225 | 3,795,031 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G244S | G244S | 1 | 1 | 0 | 0 | 244 | G | S | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,844,322 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.269181 | 0.104896 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9681326,"numValue":0.269181000751987,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9681327,"numValue":0.104896432018026,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16908,"numValue":4.0,"position":244,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12979 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,979 | train | mutant | 3,791,086 | 225 | 3,795,031 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G244S | G244S | 1 | 1 | 0 | 0 | 244 | G | S | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,687 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.254272 | 0.14541 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184056,"numValue":-0.254272356158833,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184057,"numValue":0.145409919964585,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16908,"numValue":4.0,"position":244,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12980 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,980 | train | mutant | 3,791,087 | 225 | 3,795,032 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G244T | G244T | 1 | 1 | 0 | 0 | 244 | G | T | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,844,323 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.453976 | 0.091582 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9681328,"numValue":0.453976070731917,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9681329,"numValue":0.091582449220412,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16908,"numValue":4.0,"position":244,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12981 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,981 | train | mutant | 3,791,087 | 225 | 3,795,032 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G244T | G244T | 1 | 1 | 0 | 0 | 244 | G | T | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,688 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184058,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184059,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":16908,"numValue":4.0,"position":244,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12982 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,982 | train | mutant | 3,791,088 | 225 | 3,795,033 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G244V | G244V | 1 | 1 | 0 | 0 | 244 | G | V | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,844,324 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.866499 | 0.076582 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9681330,"numValue":0.866498828660511,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9681331,"numValue":0.0765824359533534,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16908,"numValue":4.0,"position":244,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12983 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,983 | train | mutant | 3,791,088 | 225 | 3,795,033 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G244V | G244V | 1 | 1 | 0 | 0 | 244 | G | V | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,689 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.453712 | 0.57537 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184060,"numValue":-0.453712187861123,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184061,"numValue":0.575370197955352,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16908,"numValue":4.0,"position":244,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12985 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,985 | train | mutant | 3,791,089 | 225 | 3,795,034 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G244W | G244W | 1 | 1 | 0 | 0 | 244 | G | W | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,690 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184062,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184063,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":16908,"numValue":4.0,"position":244,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12986 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,986 | train | mutant | 3,791,090 | 225 | 3,795,035 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G244Y | G244Y | 1 | 1 | 0 | 0 | 244 | G | Y | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,844,326 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.377288 | 0.054527 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9681334,"numValue":0.377288027191695,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9681335,"numValue":0.0545272057263046,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16908,"numValue":4.0,"position":244,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12987 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,987 | train | mutant | 3,791,090 | 225 | 3,795,035 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | G244Y | G244Y | 1 | 1 | 0 | 0 | 244 | G | Y | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,691 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184064,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184065,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":16908,"numValue":4.0,"position":244,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12988 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,988 | train | mutant | 4,906,051 | 225 | 4,912,639 | 504 | 503 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | delG244 | delG244 | 1 | 0 | 1 | 0 | 244 | G | - | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,112 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182906,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182907,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":16908,"numValue":4.0,"position":244,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12989 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,989 | train | mutant | 3,792,363 | 225 | 3,796,308 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E245A | E245A | 1 | 1 | 0 | 0 | 245 | E | A | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,845,600 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.068659 | 0.080979 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9683882,"numValue":-0.0686585721165133,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9683883,"numValue":0.0809787948360161,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16909,"numValue":6.0,"position":245,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12990 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,990 | train | mutant | 3,792,363 | 225 | 3,796,308 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E245A | E245A | 1 | 1 | 0 | 0 | 245 | E | A | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,119 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.247275 | 0.048591 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182920,"numValue":-0.247275056417122,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182921,"numValue":0.0485907166591985,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16909,"numValue":6.0,"position":245,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12992 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,992 | train | mutant | 3,792,364 | 225 | 3,796,309 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E245C | E245C | 1 | 1 | 0 | 0 | 245 | E | C | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,120 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.345306 | 0.054371 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182922,"numValue":-0.345306477849697,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182923,"numValue":0.0543709366065132,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16909,"numValue":6.0,"position":245,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12993 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,993 | train | mutant | 3,792,365 | 225 | 3,796,310 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E245D | E245D | 1 | 1 | 0 | 0 | 245 | E | D | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,845,602 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.080316 | 0.101011 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9683886,"numValue":-0.0803155600607091,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9683887,"numValue":0.101010657967179,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16909,"numValue":6.0,"position":245,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12994 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,994 | train | mutant | 3,792,365 | 225 | 3,796,310 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E245D | E245D | 1 | 1 | 0 | 0 | 245 | E | D | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,121 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.078259 | 0.055353 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182924,"numValue":-0.0782593153054676,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182925,"numValue":0.0553532082187654,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16909,"numValue":6.0,"position":245,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12995 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,995 | train | mutant | 3,792,366 | 225 | 3,796,311 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E245F | E245F | 1 | 1 | 0 | 0 | 245 | E | F | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,845,603 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.345619 | 0.098209 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9683888,"numValue":0.345619389532244,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9683889,"numValue":0.0982088059794226,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16909,"numValue":6.0,"position":245,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12996 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,996 | train | mutant | 3,792,366 | 225 | 3,796,311 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E245F | E245F | 1 | 1 | 0 | 0 | 245 | E | F | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,662 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.610033 | 0.049086 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184006,"numValue":-0.610033009884863,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184007,"numValue":0.0490856280153899,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16909,"numValue":6.0,"position":245,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12997 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,997 | train | mutant | 3,792,367 | 225 | 3,796,312 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E245G | E245G | 1 | 1 | 0 | 0 | 245 | E | G | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,845,604 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.102801 | 0.073672 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9683890,"numValue":0.102800862415973,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9683891,"numValue":0.0736721170406541,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16909,"numValue":6.0,"position":245,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12998 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,998 | train | mutant | 3,792,367 | 225 | 3,796,312 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E245G | E245G | 1 | 1 | 0 | 0 | 245 | E | G | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,663 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.42205 | 0.051032 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184008,"numValue":-0.422050003297539,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184009,"numValue":0.0510323955205139,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16909,"numValue":6.0,"position":245,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12999 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,999 | train | mutant | 3,792,368 | 225 | 3,796,313 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E245H | E245H | 1 | 1 | 0 | 0 | 245 | E | H | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,845,605 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.054198 | 0.098501 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9683892,"numValue":0.0541983964764565,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9683893,"numValue":0.0985013046739901,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16909,"numValue":6.0,"position":245,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13000 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,000 | train | mutant | 3,792,368 | 225 | 3,796,313 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E245H | E245H | 1 | 1 | 0 | 0 | 245 | E | H | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,664 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.200576 | 0.050104 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184010,"numValue":-0.200575997758827,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184011,"numValue":0.0501040637478673,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16909,"numValue":6.0,"position":245,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13002 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,002 | train | mutant | 3,792,369 | 225 | 3,796,314 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E245I | E245I | 1 | 1 | 0 | 0 | 245 | E | I | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,665 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.480492 | 0.051741 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184012,"numValue":-0.480491539857617,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184013,"numValue":0.051740543897149,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16909,"numValue":6.0,"position":245,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13004 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,004 | train | mutant | 3,792,370 | 225 | 3,796,315 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E245K | E245K | 1 | 1 | 0 | 0 | 245 | E | K | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,666 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.201184 | 0.063298 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184014,"numValue":-0.201183905082305,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184015,"numValue":0.0632976896342925,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16909,"numValue":6.0,"position":245,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13005 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,005 | train | mutant | 3,792,371 | 225 | 3,796,316 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E245L | E245L | 1 | 1 | 0 | 0 | 245 | E | L | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,845,608 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.14553 | 0.058929 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9683898,"numValue":0.14552960654178,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9683899,"numValue":0.0589292022649099,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16909,"numValue":6.0,"position":245,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13006 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,006 | train | mutant | 3,792,371 | 225 | 3,796,316 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E245L | E245L | 1 | 1 | 0 | 0 | 245 | E | L | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,667 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.340498 | 0.045955 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184016,"numValue":-0.340498121886636,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184017,"numValue":0.0459554065843119,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16909,"numValue":6.0,"position":245,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13007 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,007 | train | mutant | 3,792,372 | 225 | 3,796,317 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E245M | E245M | 1 | 1 | 0 | 0 | 245 | E | M | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,845,609 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.108596 | 0.077401 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9683900,"numValue":0.108595747068936,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9683901,"numValue":0.0774012756590793,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16909,"numValue":6.0,"position":245,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13009 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,009 | train | mutant | 3,792,373 | 225 | 3,796,318 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E245N | E245N | 1 | 1 | 0 | 0 | 245 | E | N | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,845,610 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.002369 | 0.104826 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9683902,"numValue":0.00236858653817738,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9683903,"numValue":0.104825573096928,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16909,"numValue":6.0,"position":245,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13010 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,010 | train | mutant | 3,792,373 | 225 | 3,796,318 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E245N | E245N | 1 | 1 | 0 | 0 | 245 | E | N | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,669 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.143434 | 0.053092 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184020,"numValue":-0.143433505042088,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184021,"numValue":0.0530921589929248,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16909,"numValue":6.0,"position":245,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13011 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,011 | train | mutant | 3,792,374 | 225 | 3,796,319 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E245P | E245P | 1 | 1 | 0 | 0 | 245 | E | P | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,845,611 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.580766 | 0.101626 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9683904,"numValue":0.580766041403661,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9683905,"numValue":0.101626006425393,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16909,"numValue":6.0,"position":245,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13012 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,012 | train | mutant | 3,792,374 | 225 | 3,796,319 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E245P | E245P | 1 | 1 | 0 | 0 | 245 | E | P | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,670 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.000718 | 0.057203 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184022,"numValue":-1.00071833718983,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184023,"numValue":0.0572033311904998,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16909,"numValue":6.0,"position":245,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13013 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,013 | train | mutant | 3,792,375 | 225 | 3,796,320 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E245Q | E245Q | 1 | 1 | 0 | 0 | 245 | E | Q | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,845,612 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.102954 | 0.097044 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9683906,"numValue":-0.102953623762247,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9683907,"numValue":0.0970437849415248,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16909,"numValue":6.0,"position":245,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13014 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,014 | train | mutant | 3,792,375 | 225 | 3,796,320 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E245Q | E245Q | 1 | 1 | 0 | 0 | 245 | E | Q | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,671 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.311568 | 0.063278 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184024,"numValue":-0.311567621396656,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184025,"numValue":0.0632784498449186,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16909,"numValue":6.0,"position":245,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13015 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,015 | train | mutant | 3,792,376 | 225 | 3,796,321 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E245R | E245R | 1 | 1 | 0 | 0 | 245 | E | R | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,845,613 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.05493 | 0.080485 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9683908,"numValue":-0.0549303487638287,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9683909,"numValue":0.0804850442023846,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16909,"numValue":6.0,"position":245,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13016 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,016 | train | mutant | 3,792,376 | 225 | 3,796,321 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E245R | E245R | 1 | 1 | 0 | 0 | 245 | E | R | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,672 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.254198 | 0.046997 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184026,"numValue":-0.254198356968933,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184027,"numValue":0.0469973708764165,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16909,"numValue":6.0,"position":245,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13017 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,017 | train | mutant | 3,792,377 | 225 | 3,796,322 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E245S | E245S | 1 | 1 | 0 | 0 | 245 | E | S | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,845,614 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.031274 | 0.065136 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9683910,"numValue":-0.0312736270250204,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9683911,"numValue":0.06513588223814,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16909,"numValue":6.0,"position":245,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13018 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,018 | train | mutant | 3,792,377 | 225 | 3,796,322 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E245S | E245S | 1 | 1 | 0 | 0 | 245 | E | S | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,673 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.222348 | 0.043621 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184028,"numValue":-0.222347673393658,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184029,"numValue":0.0436207639705806,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16909,"numValue":6.0,"position":245,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13019 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,019 | train | mutant | 3,792,378 | 225 | 3,796,323 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E245T | E245T | 1 | 1 | 0 | 0 | 245 | E | T | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,845,615 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.022161 | 0.098742 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9683912,"numValue":-0.0221614724721914,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9683913,"numValue":0.0987424815697094,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16909,"numValue":6.0,"position":245,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13020 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,020 | train | mutant | 3,792,378 | 225 | 3,796,323 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E245T | E245T | 1 | 1 | 0 | 0 | 245 | E | T | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,674 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.337678 | 0.046424 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184030,"numValue":-0.337678195768302,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184031,"numValue":0.0464241954307784,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16909,"numValue":6.0,"position":245,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13021 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,021 | train | mutant | 3,792,379 | 225 | 3,796,324 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E245V | E245V | 1 | 1 | 0 | 0 | 245 | E | V | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,845,616 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.066879 | 0.09509 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9683914,"numValue":0.0668786966185972,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9683915,"numValue":0.095090144734427,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16909,"numValue":6.0,"position":245,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13022 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,022 | train | mutant | 3,792,379 | 225 | 3,796,324 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E245V | E245V | 1 | 1 | 0 | 0 | 245 | E | V | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,675 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.478306 | 0.046223 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184032,"numValue":-0.478306494961015,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184033,"numValue":0.0462233632207707,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16909,"numValue":6.0,"position":245,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13023 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,023 | train | mutant | 3,792,380 | 225 | 3,796,325 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E245W | E245W | 1 | 1 | 0 | 0 | 245 | E | W | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,845,617 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.401179 | 0.078984 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9683916,"numValue":0.401179479093509,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9683917,"numValue":0.0789844037162825,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16909,"numValue":6.0,"position":245,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13024 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,024 | train | mutant | 3,792,380 | 225 | 3,796,325 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E245W | E245W | 1 | 1 | 0 | 0 | 245 | E | W | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,676 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.639722 | 0.092851 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184034,"numValue":-0.639722041855827,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184035,"numValue":0.09285108029448,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16909,"numValue":6.0,"position":245,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13025 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,025 | train | mutant | 3,792,381 | 225 | 3,796,326 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E245Y | E245Y | 1 | 1 | 0 | 0 | 245 | E | Y | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,845,618 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.325096 | 0.11324 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9683918,"numValue":0.325095677491709,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9683919,"numValue":0.113239723953628,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16909,"numValue":6.0,"position":245,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13026 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,026 | train | mutant | 3,792,381 | 225 | 3,796,326 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | E245Y | E245Y | 1 | 1 | 0 | 0 | 245 | E | Y | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,677 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.440117 | 0.051831 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184036,"numValue":-0.440116786158052,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184037,"numValue":0.0518313878488787,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16909,"numValue":6.0,"position":245,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13027 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,027 | train | mutant | 4,906,052 | 225 | 4,912,640 | 504 | 503 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | delE245 | delE245 | 1 | 0 | 1 | 0 | 245 | E | - | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,118 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.316741 | 0.11944 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182918,"numValue":-1.31674110766356,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182919,"numValue":0.119440182760812,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16909,"numValue":6.0,"position":245,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13028 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,028 | train | mutant | 3,793,596 | 225 | 3,797,541 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I246A | I246A | 1 | 1 | 0 | 0 | 246 | I | A | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,846,835 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.032675 | 0.070669 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9686352,"numValue":-0.0326745935290013,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9686353,"numValue":0.0706691200154932,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16910,"numValue":5.0,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13029 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,029 | train | mutant | 3,793,596 | 225 | 3,797,541 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I246A | I246A | 1 | 1 | 0 | 0 | 246 | I | A | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,123 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.020763 | 0.046829 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182928,"numValue":-0.0207627404435088,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182929,"numValue":0.0468292972325182,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16910,"numValue":5.0,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13030 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,030 | train | mutant | 3,793,597 | 225 | 3,797,542 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I246C | I246C | 1 | 1 | 0 | 0 | 246 | I | C | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,846,836 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.006162 | 0.098629 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9686354,"numValue":-0.00616247613698957,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9686355,"numValue":0.0986286301769652,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16910,"numValue":5.0,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13031 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,031 | train | mutant | 3,793,597 | 225 | 3,797,542 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I246C | I246C | 1 | 1 | 0 | 0 | 246 | I | C | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,124 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.112807 | 0.053583 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182930,"numValue":-0.112807388706124,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182931,"numValue":0.0535829327600035,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16910,"numValue":5.0,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13032 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,032 | train | mutant | 3,793,598 | 225 | 3,797,543 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I246D | I246D | 1 | 1 | 0 | 0 | 246 | I | D | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,846,837 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.29241 | 0.065872 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9686356,"numValue":0.292410472566393,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9686357,"numValue":0.0658723243952151,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16910,"numValue":5.0,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13033 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,033 | train | mutant | 3,793,598 | 225 | 3,797,543 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I246D | I246D | 1 | 1 | 0 | 0 | 246 | I | D | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,125 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.283949 | 0.06343 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182932,"numValue":-0.283949214069523,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182933,"numValue":0.0634301083997026,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16910,"numValue":5.0,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13034 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,034 | train | mutant | 3,793,599 | 225 | 3,797,544 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I246E | I246E | 1 | 1 | 0 | 0 | 246 | I | E | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,846,838 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.098149 | 0.082522 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9686358,"numValue":0.0981491593544937,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9686359,"numValue":0.0825217008624783,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16910,"numValue":5.0,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13035 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,035 | train | mutant | 3,793,599 | 225 | 3,797,544 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I246E | I246E | 1 | 1 | 0 | 0 | 246 | I | E | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,126 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.123269 | 0.051669 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182934,"numValue":-0.12326912363949,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182935,"numValue":0.0516693216660959,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16910,"numValue":5.0,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13037 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,037 | train | mutant | 3,793,600 | 225 | 3,797,545 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I246F | I246F | 1 | 1 | 0 | 0 | 246 | I | F | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,127 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.189941 | 0.062966 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182936,"numValue":-0.189940802358814,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182937,"numValue":0.062966499496529,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16910,"numValue":5.0,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13038 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,038 | train | mutant | 3,793,601 | 225 | 3,797,546 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I246G | I246G | 1 | 1 | 0 | 0 | 246 | I | G | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,846,840 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.241083 | 0.083398 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9686362,"numValue":0.241082709730754,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9686363,"numValue":0.0833979523858073,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16910,"numValue":5.0,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13039 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,039 | train | mutant | 3,793,601 | 225 | 3,797,546 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I246G | I246G | 1 | 1 | 0 | 0 | 246 | I | G | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,128 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.303148 | 0.043872 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182938,"numValue":-0.303147627552354,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182939,"numValue":0.0438721463798823,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16910,"numValue":5.0,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13040 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,040 | train | mutant | 3,793,602 | 225 | 3,797,547 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I246H | I246H | 1 | 1 | 0 | 0 | 246 | I | H | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,846,841 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.083518 | 0.076593 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9686364,"numValue":0.0835180130770527,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9686365,"numValue":0.0765930698552811,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16910,"numValue":5.0,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13041 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,041 | train | mutant | 3,793,602 | 225 | 3,797,547 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I246H | I246H | 1 | 1 | 0 | 0 | 246 | I | H | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,129 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.075972 | 0.059889 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182940,"numValue":-0.0759717059402846,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182941,"numValue":0.0598891596370719,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16910,"numValue":5.0,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13042 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,042 | train | mutant | 3,793,603 | 225 | 3,797,548 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I246K | I246K | 1 | 1 | 0 | 0 | 246 | I | K | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,846,842 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.11617 | 0.095644 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9686366,"numValue":-0.116169864684577,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9686367,"numValue":0.0956443184366201,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16910,"numValue":5.0,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13043 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,043 | train | mutant | 3,793,603 | 225 | 3,797,548 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I246K | I246K | 1 | 1 | 0 | 0 | 246 | I | K | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,650 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.032956 | 0.049755 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183982,"numValue":-0.0329558972824884,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183983,"numValue":0.0497548114422465,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16910,"numValue":5.0,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13044 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,044 | train | mutant | 3,793,604 | 225 | 3,797,549 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I246L | I246L | 1 | 1 | 0 | 0 | 246 | I | L | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,846,843 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.004789 | 0.075736 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9686368,"numValue":0.00478946610491247,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9686369,"numValue":0.0757361394003222,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16910,"numValue":5.0,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13045 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,045 | train | mutant | 3,793,604 | 225 | 3,797,549 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I246L | I246L | 1 | 1 | 0 | 0 | 246 | I | L | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,651 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.104258 | 0.046689 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183984,"numValue":-0.104258493047157,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183985,"numValue":0.0466890568323048,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16910,"numValue":5.0,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13047 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,047 | train | mutant | 3,793,605 | 225 | 3,797,550 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I246M | I246M | 1 | 1 | 0 | 0 | 246 | I | M | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,652 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.123965 | 0.053862 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183986,"numValue":-0.123965352576719,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183987,"numValue":0.0538621324991858,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16910,"numValue":5.0,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13049 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,049 | train | mutant | 3,793,606 | 225 | 3,797,551 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I246N | I246N | 1 | 1 | 0 | 0 | 246 | I | N | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,653 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.119321 | 0.079566 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183988,"numValue":-0.119320908797737,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183989,"numValue":0.0795658465937196,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16910,"numValue":5.0,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13050 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,050 | train | mutant | 3,793,607 | 225 | 3,797,552 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I246P | I246P | 1 | 1 | 0 | 0 | 246 | I | P | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,846,846 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.043062 | 0.063716 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9686374,"numValue":0.0430623099368669,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9686375,"numValue":0.0637163632324575,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16910,"numValue":5.0,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13051 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,051 | train | mutant | 3,793,607 | 225 | 3,797,552 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I246P | I246P | 1 | 1 | 0 | 0 | 246 | I | P | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,654 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.039392 | 0.052475 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183990,"numValue":-0.0393922354233462,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183991,"numValue":0.0524749023094324,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16910,"numValue":5.0,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13052 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,052 | train | mutant | 3,793,608 | 225 | 3,797,553 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I246Q | I246Q | 1 | 1 | 0 | 0 | 246 | I | Q | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,846,847 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.056171 | 0.07445 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9686376,"numValue":-0.0561706386976036,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9686377,"numValue":0.0744498671242754,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16910,"numValue":5.0,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13053 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,053 | train | mutant | 3,793,608 | 225 | 3,797,553 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I246Q | I246Q | 1 | 1 | 0 | 0 | 246 | I | Q | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,655 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.07668 | 0.056197 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183992,"numValue":-0.0766798702307239,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183993,"numValue":0.0561965364058529,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16910,"numValue":5.0,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13055 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,055 | train | mutant | 3,793,609 | 225 | 3,797,554 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I246R | I246R | 1 | 1 | 0 | 0 | 246 | I | R | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,656 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.006377 | 0.042868 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183994,"numValue":0.00637745706502361,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183995,"numValue":0.0428681603816907,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16910,"numValue":5.0,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13056 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,056 | train | mutant | 3,793,610 | 225 | 3,797,555 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I246S | I246S | 1 | 1 | 0 | 0 | 246 | I | S | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,846,849 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.025257 | 0.056306 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9686380,"numValue":0.0252573119007854,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9686381,"numValue":0.0563055092071845,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16910,"numValue":5.0,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13057 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,057 | train | mutant | 3,793,610 | 225 | 3,797,555 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I246S | I246S | 1 | 1 | 0 | 0 | 246 | I | S | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,657 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.162172 | 0.045819 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183996,"numValue":-0.16217200958124,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183997,"numValue":0.0458190650661469,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16910,"numValue":5.0,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13058 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,058 | train | mutant | 3,793,611 | 225 | 3,797,556 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I246T | I246T | 1 | 1 | 0 | 0 | 246 | I | T | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,846,850 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.097559 | 0.089047 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9686382,"numValue":-0.0975591634688123,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9686383,"numValue":0.0890467193493199,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16910,"numValue":5.0,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13059 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,059 | train | mutant | 3,793,611 | 225 | 3,797,556 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I246T | I246T | 1 | 1 | 0 | 0 | 246 | I | T | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,658 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.022301 | 0.048973 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183998,"numValue":0.0223008096271259,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183999,"numValue":0.0489728946258737,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16910,"numValue":5.0,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] |
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