row_id string | dataset_id string | source_dataset string | source_file string | source_table string | source_sha string | row_index int64 | split string | subject_type string | entry_id int64 | sequence_id int64 | target_sequence_id int64 | source_sequence_length int64 | target_sequence_length int64 | protein_id int64 | protein_name string | organism string | isoform int64 | protein_ids string | protein_names string | organisms string | isoforms string | uniprot_accessions string | interpro_accessions string | ec_numbers string | megascale_ids string | other_references string | mutations string | substitutions string | deletions string | insertions string | mutation_count int64 | substitution_count int64 | deletion_count int64 | insertion_count int64 | first_position int64 | first_source_aa string | first_target_aa string | conservation float64 | feature_types string | pdb_ids string | afdb_ids string | structure_ids string | structure_methods string | structure_resolution_min float64 | residue_positions string | residue_chain_names string | residue_secondary_structures string | residue_in_pocket_any bool | residue_in_tunnel_any bool | residue_asa_mean float64 | residue_bfactor_mean float64 | experiment_id int64 | experiment_dataset string | ph float64 | measure string | method string | buffer string | buffer_conc string | exp_temperature float64 | ion string | ion_conc string | pdb_chain_mutation string | tm float64 | dtm float64 | dg float64 | dg_text string | ddg float64 | dh float64 | dcp float64 | dhvh float64 | cm float64 | m_value float64 | trypsin_ml float64 | chymotrypsin_ml float64 | stabilizing float64 | stabilizing_text string | domainome_fitness float64 | domainome_fitness_std float64 | domainome_ddg float64 | domainome_ddg_std float64 | reversibility string | state string | measurement_types string | measurement_datasets string | annotation_types string | publication_id string | publication_type string | publication_title string | publication_year int64 | publication_doi string | publication_pmid string | publication_journal string | publication_url string | publication_author_count int64 | publication_authors string | annotations_json string | measurements_json string | features_json string |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
fireprotdb:13060 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,060 | train | mutant | 3,793,612 | 225 | 3,797,557 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I246V | I246V | 1 | 1 | 0 | 0 | 246 | I | V | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,846,851 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.073127 | 0.101193 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9686384,"numValue":-0.0731272505345291,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9686385,"numValue":0.10119303219844,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16910,"numValue":5.0,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13061 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,061 | train | mutant | 3,793,612 | 225 | 3,797,557 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I246V | I246V | 1 | 1 | 0 | 0 | 246 | I | V | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,659 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.02136 | 0.051219 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184000,"numValue":0.0213603037942055,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184001,"numValue":0.051218730254823,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16910,"numValue":5.0,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13062 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,062 | train | mutant | 3,793,613 | 225 | 3,797,558 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I246W | I246W | 1 | 1 | 0 | 0 | 246 | I | W | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,846,852 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.246504 | 0.085293 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9686386,"numValue":0.246504413068175,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9686387,"numValue":0.085292704407119,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16910,"numValue":5.0,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13063 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,063 | train | mutant | 3,793,613 | 225 | 3,797,558 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I246W | I246W | 1 | 1 | 0 | 0 | 246 | I | W | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,660 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.174907 | 0.049108 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184002,"numValue":-0.174907031455938,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184003,"numValue":0.049107891427577,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16910,"numValue":5.0,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13064 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,064 | train | mutant | 3,793,614 | 225 | 3,797,559 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I246Y | I246Y | 1 | 1 | 0 | 0 | 246 | I | Y | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,846,853 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.176485 | 0.158714 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9686388,"numValue":0.176485423935084,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9686389,"numValue":0.158714215825678,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16910,"numValue":5.0,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13065 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,065 | train | mutant | 3,793,614 | 225 | 3,797,559 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I246Y | I246Y | 1 | 1 | 0 | 0 | 246 | I | Y | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,661 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.121527 | 0.071837 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184004,"numValue":-0.121527357761094,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184005,"numValue":0.0718372200194401,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16910,"numValue":5.0,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13066 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,066 | train | mutant | 4,906,053 | 225 | 4,912,641 | 504 | 503 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | delI246 | delI246 | 1 | 0 | 1 | 0 | 246 | I | - | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,122 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.255011 | 0.086094 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182926,"numValue":-1.2550112937683,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182927,"numValue":0.0860936015832612,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16910,"numValue":5.0,"position":246,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13067 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,067 | train | mutant | 3,794,906 | 225 | 3,798,851 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y247A | Y247A | 1 | 1 | 0 | 0 | 247 | Y | A | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,848,146 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.47753 | 0.12252 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9688974,"numValue":0.477530050973615,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9688975,"numValue":0.122519947045104,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16911,"numValue":6.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13068 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,068 | train | mutant | 3,794,906 | 225 | 3,798,851 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y247A | Y247A | 1 | 1 | 0 | 0 | 247 | Y | A | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,131 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.724855 | 0.04625 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182944,"numValue":-0.724855484057883,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182945,"numValue":0.0462499392739175,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16911,"numValue":6.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13070 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,070 | train | mutant | 3,794,907 | 225 | 3,798,852 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y247C | Y247C | 1 | 1 | 0 | 0 | 247 | Y | C | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,132 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.664043 | 0.056724 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182946,"numValue":-0.664043188505262,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182947,"numValue":0.0567244689059243,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16911,"numValue":6.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13071 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,071 | train | mutant | 3,794,908 | 225 | 3,798,853 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y247D | Y247D | 1 | 1 | 0 | 0 | 247 | Y | D | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,848,148 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.603727 | 0.058763 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9688978,"numValue":0.603726559895345,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9688979,"numValue":0.0587631963656532,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16911,"numValue":6.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13072 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,072 | train | mutant | 3,794,908 | 225 | 3,798,853 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y247D | Y247D | 1 | 1 | 0 | 0 | 247 | Y | D | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,133 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.710971 | 0.060397 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182948,"numValue":-0.710971008100075,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182949,"numValue":0.0603969293471211,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16911,"numValue":6.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13074 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,074 | train | mutant | 3,794,909 | 225 | 3,798,854 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y247E | Y247E | 1 | 1 | 0 | 0 | 247 | Y | E | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,134 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.674576 | 0.049749 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182950,"numValue":-0.674575580729629,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182951,"numValue":0.0497494087056936,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16911,"numValue":6.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13075 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,075 | train | mutant | 3,794,910 | 225 | 3,798,855 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y247F | Y247F | 1 | 1 | 0 | 0 | 247 | Y | F | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,848,150 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.065695 | 0.085651 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9688982,"numValue":0.065694771991442,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9688983,"numValue":0.0856505098881706,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16911,"numValue":6.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13076 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,076 | train | mutant | 3,794,910 | 225 | 3,798,855 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y247F | Y247F | 1 | 1 | 0 | 0 | 247 | Y | F | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,135 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.169402 | 0.069937 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182952,"numValue":-0.169402446555647,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182953,"numValue":0.0699366105036288,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16911,"numValue":6.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13077 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,077 | train | mutant | 3,794,911 | 225 | 3,798,856 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y247G | Y247G | 1 | 1 | 0 | 0 | 247 | Y | G | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,848,151 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.627587 | 0.150399 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9688984,"numValue":0.627587010315877,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9688985,"numValue":0.150398605793507,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16911,"numValue":6.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13078 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,078 | train | mutant | 3,794,911 | 225 | 3,798,856 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y247G | Y247G | 1 | 1 | 0 | 0 | 247 | Y | G | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,136 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.863075 | 0.044036 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182954,"numValue":-0.863075467679953,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182955,"numValue":0.0440355572791266,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16911,"numValue":6.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13079 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,079 | train | mutant | 3,794,912 | 225 | 3,798,857 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y247H | Y247H | 1 | 1 | 0 | 0 | 247 | Y | H | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,848,152 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.350048 | 0.145614 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9688986,"numValue":0.350048381553097,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9688987,"numValue":0.145613912566375,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16911,"numValue":6.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13080 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,080 | train | mutant | 3,794,912 | 225 | 3,798,857 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y247H | Y247H | 1 | 1 | 0 | 0 | 247 | Y | H | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,137 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.564068 | 0.086359 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182956,"numValue":-0.564068214156027,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182957,"numValue":0.0863586459935368,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16911,"numValue":6.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13081 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,081 | train | mutant | 3,794,913 | 225 | 3,798,858 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y247I | Y247I | 1 | 1 | 0 | 0 | 247 | Y | I | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,848,153 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.325908 | 0.1019 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9688988,"numValue":0.325907713750763,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9688989,"numValue":0.101899967246907,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16911,"numValue":6.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13082 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,082 | train | mutant | 3,794,913 | 225 | 3,798,858 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y247I | Y247I | 1 | 1 | 0 | 0 | 247 | Y | I | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,138 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.031501 | 0.152659 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182958,"numValue":-1.03150056794577,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182959,"numValue":0.152659453504127,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16911,"numValue":6.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13083 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,083 | train | mutant | 3,794,914 | 225 | 3,798,859 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y247K | Y247K | 1 | 1 | 0 | 0 | 247 | Y | K | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,848,154 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.449246 | 0.083903 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9688990,"numValue":0.449246347463427,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9688991,"numValue":0.0839029603268339,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16911,"numValue":6.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13084 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,084 | train | mutant | 3,794,914 | 225 | 3,798,859 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y247K | Y247K | 1 | 1 | 0 | 0 | 247 | Y | K | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,139 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.822455 | 0.067204 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182960,"numValue":-0.822455084411333,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182961,"numValue":0.0672039716017685,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16911,"numValue":6.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13085 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,085 | train | mutant | 3,794,915 | 225 | 3,798,860 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y247L | Y247L | 1 | 1 | 0 | 0 | 247 | Y | L | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,848,155 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.359797 | 0.049449 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9688992,"numValue":0.359797058969703,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9688993,"numValue":0.0494493375109482,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16911,"numValue":6.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13086 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,086 | train | mutant | 3,794,915 | 225 | 3,798,860 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y247L | Y247L | 1 | 1 | 0 | 0 | 247 | Y | L | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,140 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.789714 | 0.047857 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182962,"numValue":-0.78971354607249,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182963,"numValue":0.0478570664112055,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16911,"numValue":6.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13087 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,087 | train | mutant | 3,794,916 | 225 | 3,798,861 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y247M | Y247M | 1 | 1 | 0 | 0 | 247 | Y | M | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,848,156 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.323828 | 0.11122 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9688994,"numValue":0.323828217657189,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9688995,"numValue":0.111219557155847,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16911,"numValue":6.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13088 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,088 | train | mutant | 3,794,916 | 225 | 3,798,861 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y247M | Y247M | 1 | 1 | 0 | 0 | 247 | Y | M | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,141 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.810933 | 0.055722 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182964,"numValue":-0.810932773991758,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182965,"numValue":0.0557217082706623,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16911,"numValue":6.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13089 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,089 | train | mutant | 3,794,917 | 225 | 3,798,862 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y247N | Y247N | 1 | 1 | 0 | 0 | 247 | Y | N | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,848,157 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.660554 | 0.142035 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9688996,"numValue":0.660553963004648,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9688997,"numValue":0.142035092565033,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16911,"numValue":6.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13090 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,090 | train | mutant | 3,794,917 | 225 | 3,798,862 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y247N | Y247N | 1 | 1 | 0 | 0 | 247 | Y | N | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,142 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.853552 | 0.083088 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182966,"numValue":-0.853551692370822,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182967,"numValue":0.0830884387831139,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16911,"numValue":6.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13091 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,091 | train | mutant | 3,794,918 | 225 | 3,798,863 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y247P | Y247P | 1 | 1 | 0 | 0 | 247 | Y | P | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,848,158 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.796469 | 0.147681 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9688998,"numValue":0.796469239383912,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9688999,"numValue":0.147680850528148,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16911,"numValue":6.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13093 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,093 | train | mutant | 3,794,919 | 225 | 3,798,864 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y247Q | Y247Q | 1 | 1 | 0 | 0 | 247 | Y | Q | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,848,159 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.365343 | 0.068343 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9689000,"numValue":0.365343173333274,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9689001,"numValue":0.0683433900150614,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16911,"numValue":6.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13094 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,094 | train | mutant | 3,794,919 | 225 | 3,798,864 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y247Q | Y247Q | 1 | 1 | 0 | 0 | 247 | Y | Q | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,144 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.699152 | 0.054864 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182970,"numValue":-0.699151905230686,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182971,"numValue":0.0548642884098852,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16911,"numValue":6.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13095 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,095 | train | mutant | 3,794,920 | 225 | 3,798,865 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y247R | Y247R | 1 | 1 | 0 | 0 | 247 | Y | R | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,848,160 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.560987 | 0.100314 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9689002,"numValue":0.560986893795769,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9689003,"numValue":0.100314480601509,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16911,"numValue":6.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13096 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,096 | train | mutant | 3,794,920 | 225 | 3,798,865 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y247R | Y247R | 1 | 1 | 0 | 0 | 247 | Y | R | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,145 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.80388 | 0.043694 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182972,"numValue":-0.803879537228004,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182973,"numValue":0.0436940868237985,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16911,"numValue":6.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13097 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,097 | train | mutant | 3,794,921 | 225 | 3,798,866 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y247S | Y247S | 1 | 1 | 0 | 0 | 247 | Y | S | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,848,161 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.488591 | 0.124882 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9689004,"numValue":0.488590996899318,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9689005,"numValue":0.124882079873828,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16911,"numValue":6.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13098 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,098 | train | mutant | 3,794,921 | 225 | 3,798,866 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y247S | Y247S | 1 | 1 | 0 | 0 | 247 | Y | S | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,146 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.930426 | 0.052218 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182974,"numValue":-0.930425551875714,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182975,"numValue":0.0522181410342842,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16911,"numValue":6.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13099 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,099 | train | mutant | 3,794,922 | 225 | 3,798,867 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y247T | Y247T | 1 | 1 | 0 | 0 | 247 | Y | T | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,848,162 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.451346 | 0.087298 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9689006,"numValue":0.451346379928449,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9689007,"numValue":0.0872975268782674,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16911,"numValue":6.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13100 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,100 | train | mutant | 3,794,922 | 225 | 3,798,867 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y247T | Y247T | 1 | 1 | 0 | 0 | 247 | Y | T | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,147 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.827948 | 0.05884 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182976,"numValue":-0.827947893096458,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182977,"numValue":0.0588399863916285,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16911,"numValue":6.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13101 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,101 | train | mutant | 3,794,923 | 225 | 3,798,868 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y247V | Y247V | 1 | 1 | 0 | 0 | 247 | Y | V | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,848,163 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.317058 | 0.062918 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9689008,"numValue":0.31705789924641,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9689009,"numValue":0.0629177166875878,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16911,"numValue":6.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13102 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,102 | train | mutant | 3,794,923 | 225 | 3,798,868 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y247V | Y247V | 1 | 1 | 0 | 0 | 247 | Y | V | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,148 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.808112 | 0.045683 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182978,"numValue":-0.808112450028317,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182979,"numValue":0.045682723547982,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16911,"numValue":6.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13103 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,103 | train | mutant | 3,794,924 | 225 | 3,798,869 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y247W | Y247W | 1 | 1 | 0 | 0 | 247 | Y | W | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,848,164 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.418486 | 0.09621 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9689010,"numValue":0.418485755006148,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9689011,"numValue":0.096210435867391,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16911,"numValue":6.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13105 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,105 | train | mutant | 4,906,054 | 225 | 4,912,642 | 504 | 503 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | delY247 | delY247 | 1 | 0 | 1 | 0 | 247 | Y | - | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,130 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.182749 | 0.074164 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182942,"numValue":-1.18274865797596,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182943,"numValue":0.07416427174853,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16911,"numValue":6.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13106 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,106 | train | mutant | 4,906,054 | 225 | 4,912,642 | 504 | 503 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | delY247 | delY247 | 1 | 0 | 1 | 0 | 247 | Y | - | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,150 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.211174 | 0.080081 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182982,"numValue":-1.21117407818881,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182983,"numValue":0.0800812867574316,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16911,"numValue":6.0,"position":247,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13107 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,107 | train | mutant | 3,796,214 | 225 | 3,800,159 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y248A | Y248A | 1 | 1 | 0 | 0 | 248 | Y | A | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,849,457 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.640788 | 0.024039 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9691596,"numValue":0.64078823999464,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9691597,"numValue":0.0240387432589586,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16912,"numValue":6.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13108 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,108 | train | mutant | 3,796,214 | 225 | 3,800,159 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y248A | Y248A | 1 | 1 | 0 | 0 | 248 | Y | A | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,151 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.999962 | 0.059451 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182984,"numValue":-0.999962192779483,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182985,"numValue":0.0594507502429749,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16912,"numValue":6.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13109 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,109 | train | mutant | 3,796,215 | 225 | 3,800,160 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y248C | Y248C | 1 | 1 | 0 | 0 | 248 | Y | C | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,849,458 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.914328 | 0.100251 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9691598,"numValue":0.914327531385669,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9691599,"numValue":0.10025104853255,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16912,"numValue":6.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13110 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,110 | train | mutant | 3,796,215 | 225 | 3,800,160 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y248C | Y248C | 1 | 1 | 0 | 0 | 248 | Y | C | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,152 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.886869 | 0.06121 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182986,"numValue":-0.886868514734371,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182987,"numValue":0.061210108832001,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16912,"numValue":6.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13111 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,111 | train | mutant | 3,796,216 | 225 | 3,800,161 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y248D | Y248D | 1 | 1 | 0 | 0 | 248 | Y | D | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,849,459 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.541327 | 0.114174 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9691600,"numValue":0.541326688350179,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9691601,"numValue":0.114173920677578,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16912,"numValue":6.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13112 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,112 | train | mutant | 3,796,216 | 225 | 3,800,161 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y248D | Y248D | 1 | 1 | 0 | 0 | 248 | Y | D | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,153 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.983383 | 0.070391 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182988,"numValue":-0.983382634497914,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182989,"numValue":0.0703911803659716,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16912,"numValue":6.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13113 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,113 | train | mutant | 3,796,217 | 225 | 3,800,162 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y248E | Y248E | 1 | 1 | 0 | 0 | 248 | Y | E | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,849,460 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.627814 | 0.10189 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9691602,"numValue":0.627813979418397,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9691603,"numValue":0.101890193059378,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16912,"numValue":6.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13114 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,114 | train | mutant | 3,796,217 | 225 | 3,800,162 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y248E | Y248E | 1 | 1 | 0 | 0 | 248 | Y | E | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,154 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.080299 | 0.070235 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182990,"numValue":-1.08029857781952,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182991,"numValue":0.0702351136874022,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16912,"numValue":6.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13115 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,115 | train | mutant | 3,796,218 | 225 | 3,800,163 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y248F | Y248F | 1 | 1 | 0 | 0 | 248 | Y | F | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,849,461 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.049894 | 0.080501 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9691604,"numValue":0.0498942847237751,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9691605,"numValue":0.0805007306143287,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16912,"numValue":6.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13116 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,116 | train | mutant | 3,796,218 | 225 | 3,800,163 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y248F | Y248F | 1 | 1 | 0 | 0 | 248 | Y | F | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,155 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.040021 | 0.06547 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182992,"numValue":0.0400208306923878,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182993,"numValue":0.0654703695049689,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16912,"numValue":6.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13117 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,117 | train | mutant | 3,796,219 | 225 | 3,800,164 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y248G | Y248G | 1 | 1 | 0 | 0 | 248 | Y | G | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,849,462 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.642125 | 0.070109 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9691606,"numValue":0.64212480331248,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9691607,"numValue":0.0701089361894699,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16912,"numValue":6.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13118 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,118 | train | mutant | 3,796,219 | 225 | 3,800,164 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y248G | Y248G | 1 | 1 | 0 | 0 | 248 | Y | G | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,156 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.916202 | 0.047226 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182994,"numValue":-0.916201952748708,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182995,"numValue":0.0472256543988065,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16912,"numValue":6.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13119 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,119 | train | mutant | 3,796,220 | 225 | 3,800,165 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y248H | Y248H | 1 | 1 | 0 | 0 | 248 | Y | H | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,849,463 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.734066 | 0.218674 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9691608,"numValue":0.734065620654258,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9691609,"numValue":0.218673916330619,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16912,"numValue":6.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13120 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,120 | train | mutant | 3,796,220 | 225 | 3,800,165 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y248H | Y248H | 1 | 1 | 0 | 0 | 248 | Y | H | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,157 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.757738 | 0.094896 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182996,"numValue":-0.75773841654775,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182997,"numValue":0.0948963224204858,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16912,"numValue":6.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13121 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,121 | train | mutant | 3,796,221 | 225 | 3,800,166 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y248I | Y248I | 1 | 1 | 0 | 0 | 248 | Y | I | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,849,464 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.841007 | 0.246857 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9691610,"numValue":0.841007283970758,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9691611,"numValue":0.246857087269566,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16912,"numValue":6.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13122 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,122 | train | mutant | 3,796,221 | 225 | 3,800,166 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y248I | Y248I | 1 | 1 | 0 | 0 | 248 | Y | I | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,158 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.975187 | 0.082394 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182998,"numValue":-0.975187104862975,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182999,"numValue":0.082393960364355,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16912,"numValue":6.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13123 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,123 | train | mutant | 3,796,222 | 225 | 3,800,167 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y248K | Y248K | 1 | 1 | 0 | 0 | 248 | Y | K | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,849,465 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.672237 | 0.090817 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9691612,"numValue":0.672237290392486,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9691613,"numValue":0.0908172358882591,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16912,"numValue":6.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13124 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,124 | train | mutant | 3,796,222 | 225 | 3,800,167 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y248K | Y248K | 1 | 1 | 0 | 0 | 248 | Y | K | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,159 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.998969 | 0.074788 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183000,"numValue":-0.998968773547333,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183001,"numValue":0.074788164488407,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16912,"numValue":6.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13125 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,125 | train | mutant | 3,796,223 | 225 | 3,800,168 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y248L | Y248L | 1 | 1 | 0 | 0 | 248 | Y | L | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,849,466 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.843511 | 0.05395 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9691614,"numValue":0.843511370950611,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9691615,"numValue":0.0539496014308906,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16912,"numValue":6.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13126 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,126 | train | mutant | 3,796,223 | 225 | 3,800,168 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y248L | Y248L | 1 | 1 | 0 | 0 | 248 | Y | L | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,160 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.937515 | 0.047498 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183002,"numValue":-0.937514674268118,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183003,"numValue":0.0474984727024727,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16912,"numValue":6.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13127 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,127 | train | mutant | 3,796,224 | 225 | 3,800,169 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y248M | Y248M | 1 | 1 | 0 | 0 | 248 | Y | M | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,849,467 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.955222 | 0.116639 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9691616,"numValue":0.955222311149649,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9691617,"numValue":0.11663873536354,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16912,"numValue":6.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13128 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,128 | train | mutant | 3,796,224 | 225 | 3,800,169 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y248M | Y248M | 1 | 1 | 0 | 0 | 248 | Y | M | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,161 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.001442 | 0.062681 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183004,"numValue":-1.00144217657748,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183005,"numValue":0.0626811172443841,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16912,"numValue":6.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13129 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,129 | train | mutant | 3,796,225 | 225 | 3,800,170 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y248N | Y248N | 1 | 1 | 0 | 0 | 248 | Y | N | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,849,468 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.856674 | 0.105344 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9691618,"numValue":0.856673553391607,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9691619,"numValue":0.105344282454872,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16912,"numValue":6.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13130 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,130 | train | mutant | 3,796,225 | 225 | 3,800,170 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y248N | Y248N | 1 | 1 | 0 | 0 | 248 | Y | N | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,162 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.993697 | 0.131185 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183006,"numValue":-0.993696609758544,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183007,"numValue":0.131184729457152,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16912,"numValue":6.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13131 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,131 | train | mutant | 3,796,226 | 225 | 3,800,171 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y248P | Y248P | 1 | 1 | 0 | 0 | 248 | Y | P | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,849,469 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.711373 | 0.090084 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9691620,"numValue":0.711373492844983,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9691621,"numValue":0.0900840199107424,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16912,"numValue":6.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13132 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,132 | train | mutant | 3,796,226 | 225 | 3,800,171 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y248P | Y248P | 1 | 1 | 0 | 0 | 248 | Y | P | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,163 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.895625 | 0.06107 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183008,"numValue":-0.895624687694078,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183009,"numValue":0.0610700196129283,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16912,"numValue":6.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13133 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,133 | train | mutant | 3,796,227 | 225 | 3,800,172 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y248Q | Y248Q | 1 | 1 | 0 | 0 | 248 | Y | Q | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,849,470 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.624174 | 0.08835 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9691622,"numValue":0.624173696589194,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9691623,"numValue":0.0883498668152733,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16912,"numValue":6.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13134 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,134 | train | mutant | 3,796,227 | 225 | 3,800,172 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y248Q | Y248Q | 1 | 1 | 0 | 0 | 248 | Y | Q | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,164 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.055907 | 0.087814 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183010,"numValue":-1.05590725129321,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183011,"numValue":0.0878143612400073,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16912,"numValue":6.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13135 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,135 | train | mutant | 3,796,228 | 225 | 3,800,173 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y248R | Y248R | 1 | 1 | 0 | 0 | 248 | Y | R | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,849,471 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.806657 | 0.079356 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9691624,"numValue":0.806656855014795,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9691625,"numValue":0.0793560276434368,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16912,"numValue":6.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13136 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,136 | train | mutant | 3,796,228 | 225 | 3,800,173 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y248R | Y248R | 1 | 1 | 0 | 0 | 248 | Y | R | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,165 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.943992 | 0.047168 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183012,"numValue":-0.943991592609889,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183013,"numValue":0.0471678952461739,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16912,"numValue":6.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13138 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,138 | train | mutant | 3,796,229 | 225 | 3,800,174 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y248S | Y248S | 1 | 1 | 0 | 0 | 248 | Y | S | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,166 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.917054 | 0.051778 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183014,"numValue":-0.917054136967878,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183015,"numValue":0.0517783153116064,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16912,"numValue":6.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13139 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,139 | train | mutant | 3,796,230 | 225 | 3,800,175 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y248T | Y248T | 1 | 1 | 0 | 0 | 248 | Y | T | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,849,473 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.751459 | 0.071823 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9691628,"numValue":0.751459330871635,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9691629,"numValue":0.0718225157792307,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16912,"numValue":6.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13140 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,140 | train | mutant | 3,796,230 | 225 | 3,800,175 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y248T | Y248T | 1 | 1 | 0 | 0 | 248 | Y | T | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,167 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.956884 | 0.060679 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183016,"numValue":-0.956884240715975,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183017,"numValue":0.0606785241138475,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16912,"numValue":6.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13141 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,141 | train | mutant | 3,796,231 | 225 | 3,800,176 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y248V | Y248V | 1 | 1 | 0 | 0 | 248 | Y | V | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,849,474 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.791873 | 0.076473 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9691630,"numValue":0.791873480774098,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9691631,"numValue":0.0764733692538363,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16912,"numValue":6.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13142 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,142 | train | mutant | 3,796,231 | 225 | 3,800,176 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y248V | Y248V | 1 | 1 | 0 | 0 | 248 | Y | V | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,168 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.865894 | 0.049881 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183018,"numValue":-0.865893643279815,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183019,"numValue":0.0498810079101832,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16912,"numValue":6.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13143 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,143 | train | mutant | 3,796,232 | 225 | 3,800,177 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y248W | Y248W | 1 | 1 | 0 | 0 | 248 | Y | W | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,849,475 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.052374 | 0.071937 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9691632,"numValue":0.0523744651167023,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9691633,"numValue":0.0719373180341049,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16912,"numValue":6.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13144 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,144 | train | mutant | 3,796,232 | 225 | 3,800,177 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Y248W | Y248W | 1 | 1 | 0 | 0 | 248 | Y | W | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,169 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.111248 | 0.0498 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183020,"numValue":-0.111247835886729,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183021,"numValue":0.0497996485858041,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16912,"numValue":6.0,"position":248,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13145 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,145 | train | mutant | 3,797,523 | 225 | 3,801,468 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I249A | I249A | 1 | 1 | 0 | 0 | 249 | I | A | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,850,768 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.225054 | 0.077047 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9694218,"numValue":0.225053818627768,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9694219,"numValue":0.0770469630490948,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16913,"numValue":8.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13146 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,146 | train | mutant | 3,797,523 | 225 | 3,801,468 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I249A | I249A | 1 | 1 | 0 | 0 | 249 | I | A | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,171 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.434483 | 0.049071 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183024,"numValue":-0.434482981167011,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183025,"numValue":0.0490709077464313,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16913,"numValue":8.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13147 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,147 | train | mutant | 3,797,524 | 225 | 3,801,469 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I249C | I249C | 1 | 1 | 0 | 0 | 249 | I | C | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,850,769 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.136303 | 0.086465 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9694220,"numValue":0.136302778016068,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9694221,"numValue":0.0864651612994018,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16913,"numValue":8.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13148 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,148 | train | mutant | 3,797,524 | 225 | 3,801,469 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I249C | I249C | 1 | 1 | 0 | 0 | 249 | I | C | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,172 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.399392 | 0.059556 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183026,"numValue":-0.399391928764338,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183027,"numValue":0.0595564497309996,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16913,"numValue":8.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13149 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,149 | train | mutant | 3,797,525 | 225 | 3,801,470 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I249D | I249D | 1 | 1 | 0 | 0 | 249 | I | D | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,850,770 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.604577 | 0.118342 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9694222,"numValue":0.60457738457762,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9694223,"numValue":0.118341525762646,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16913,"numValue":8.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13150 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,150 | train | mutant | 3,797,525 | 225 | 3,801,470 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I249D | I249D | 1 | 1 | 0 | 0 | 249 | I | D | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,173 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.882722 | 0.058203 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183028,"numValue":-0.882721934322274,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183029,"numValue":0.0582030522891444,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16913,"numValue":8.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13151 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,151 | train | mutant | 3,797,526 | 225 | 3,801,471 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I249E | I249E | 1 | 1 | 0 | 0 | 249 | I | E | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,850,771 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.204108 | 0.066712 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9694224,"numValue":0.204108497694616,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9694225,"numValue":0.0667115755662389,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16913,"numValue":8.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13152 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,152 | train | mutant | 3,797,526 | 225 | 3,801,471 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I249E | I249E | 1 | 1 | 0 | 0 | 249 | I | E | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,174 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.458396 | 0.052019 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183030,"numValue":-0.458396257012761,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183031,"numValue":0.0520194014895392,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16913,"numValue":8.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13153 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,153 | train | mutant | 3,797,527 | 225 | 3,801,472 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I249F | I249F | 1 | 1 | 0 | 0 | 249 | I | F | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,850,772 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.194809 | 0.074053 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9694226,"numValue":0.194808728478645,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9694227,"numValue":0.0740533564907684,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16913,"numValue":8.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13154 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,154 | train | mutant | 3,797,527 | 225 | 3,801,472 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I249F | I249F | 1 | 1 | 0 | 0 | 249 | I | F | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,175 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.506901 | 0.070372 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183032,"numValue":-0.506901055042654,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183033,"numValue":0.0703717814385548,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16913,"numValue":8.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13155 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,155 | train | mutant | 3,797,528 | 225 | 3,801,473 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I249G | I249G | 1 | 1 | 0 | 0 | 249 | I | G | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,850,773 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.590519 | 0.067887 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9694228,"numValue":0.590519028645069,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9694229,"numValue":0.0678870605886896,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16913,"numValue":8.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13157 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,157 | train | mutant | 3,797,529 | 225 | 3,801,474 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I249H | I249H | 1 | 1 | 0 | 0 | 249 | I | H | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,850,774 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.314878 | 0.053095 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9694230,"numValue":0.314877938098434,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9694231,"numValue":0.053094723487796,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16913,"numValue":8.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13158 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,158 | train | mutant | 3,797,529 | 225 | 3,801,474 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I249H | I249H | 1 | 1 | 0 | 0 | 249 | I | H | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,177 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.367793 | 0.081084 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183036,"numValue":-0.367793478986894,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183037,"numValue":0.0810840155650851,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16913,"numValue":8.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13159 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,159 | train | mutant | 3,797,530 | 225 | 3,801,475 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I249K | I249K | 1 | 1 | 0 | 0 | 249 | I | K | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,850,775 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.027485 | 0.160237 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9694232,"numValue":0.027485100851262,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9694233,"numValue":0.160237463199582,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16913,"numValue":8.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13160 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,160 | train | mutant | 3,797,530 | 225 | 3,801,475 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I249K | I249K | 1 | 1 | 0 | 0 | 249 | I | K | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,638 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.314737 | 0.070389 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183958,"numValue":-0.314736855518925,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183959,"numValue":0.0703889922178831,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16913,"numValue":8.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13161 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,161 | train | mutant | 3,797,531 | 225 | 3,801,476 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I249L | I249L | 1 | 1 | 0 | 0 | 249 | I | L | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,850,776 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.004305 | 0.071641 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9694234,"numValue":0.00430515241220545,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9694235,"numValue":0.0716414412470943,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16913,"numValue":8.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13162 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,162 | train | mutant | 3,797,531 | 225 | 3,801,476 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I249L | I249L | 1 | 1 | 0 | 0 | 249 | I | L | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,639 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.068234 | 0.046763 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183960,"numValue":-0.0682344142995747,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183961,"numValue":0.0467628650565533,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16913,"numValue":8.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13163 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,163 | train | mutant | 3,797,532 | 225 | 3,801,477 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I249M | I249M | 1 | 1 | 0 | 0 | 249 | I | M | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,850,777 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.011058 | 0.073514 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9694236,"numValue":-0.0110581422890211,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9694237,"numValue":0.0735138519468324,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16913,"numValue":8.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13164 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,164 | train | mutant | 3,797,532 | 225 | 3,801,477 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I249M | I249M | 1 | 1 | 0 | 0 | 249 | I | M | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,640 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.117915 | 0.052906 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183962,"numValue":-0.11791492418964,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183963,"numValue":0.0529060947932885,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16913,"numValue":8.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13165 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,165 | train | mutant | 3,797,533 | 225 | 3,801,478 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I249N | I249N | 1 | 1 | 0 | 0 | 249 | I | N | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,850,778 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.444491 | 0.09401 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9694238,"numValue":0.444490720234898,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9694239,"numValue":0.0940096750323007,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16913,"numValue":8.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] |
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