row_id string | dataset_id string | source_dataset string | source_file string | source_table string | source_sha string | row_index int64 | split string | subject_type string | entry_id int64 | sequence_id int64 | target_sequence_id int64 | source_sequence_length int64 | target_sequence_length int64 | protein_id int64 | protein_name string | organism string | isoform int64 | protein_ids string | protein_names string | organisms string | isoforms string | uniprot_accessions string | interpro_accessions string | ec_numbers string | megascale_ids string | other_references string | mutations string | substitutions string | deletions string | insertions string | mutation_count int64 | substitution_count int64 | deletion_count int64 | insertion_count int64 | first_position int64 | first_source_aa string | first_target_aa string | conservation float64 | feature_types string | pdb_ids string | afdb_ids string | structure_ids string | structure_methods string | structure_resolution_min float64 | residue_positions string | residue_chain_names string | residue_secondary_structures string | residue_in_pocket_any bool | residue_in_tunnel_any bool | residue_asa_mean float64 | residue_bfactor_mean float64 | experiment_id int64 | experiment_dataset string | ph float64 | measure string | method string | buffer string | buffer_conc string | exp_temperature float64 | ion string | ion_conc string | pdb_chain_mutation string | tm float64 | dtm float64 | dg float64 | dg_text string | ddg float64 | dh float64 | dcp float64 | dhvh float64 | cm float64 | m_value float64 | trypsin_ml float64 | chymotrypsin_ml float64 | stabilizing float64 | stabilizing_text string | domainome_fitness float64 | domainome_fitness_std float64 | domainome_ddg float64 | domainome_ddg_std float64 | reversibility string | state string | measurement_types string | measurement_datasets string | annotation_types string | publication_id string | publication_type string | publication_title string | publication_year int64 | publication_doi string | publication_pmid string | publication_journal string | publication_url string | publication_author_count int64 | publication_authors string | annotations_json string | measurements_json string | features_json string |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
fireprotdb:13166 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,166 | train | mutant | 3,797,533 | 225 | 3,801,478 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I249N | I249N | 1 | 1 | 0 | 0 | 249 | I | N | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,641 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.515522 | 0.081576 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183964,"numValue":-0.5155216423899,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183965,"numValue":0.0815756725483013,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16913,"numValue":8.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13167 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,167 | train | mutant | 3,797,534 | 225 | 3,801,479 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I249P | I249P | 1 | 1 | 0 | 0 | 249 | I | P | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,850,779 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.734269 | 0.219955 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9694240,"numValue":0.734268722554673,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9694241,"numValue":0.219955475931399,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16913,"numValue":8.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13169 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,169 | train | mutant | 3,797,535 | 225 | 3,801,480 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I249Q | I249Q | 1 | 1 | 0 | 0 | 249 | I | Q | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,850,780 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.147929 | 0.066743 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9694242,"numValue":0.147929031170492,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9694243,"numValue":0.0667432916007184,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16913,"numValue":8.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13170 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,170 | train | mutant | 3,797,535 | 225 | 3,801,480 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I249Q | I249Q | 1 | 1 | 0 | 0 | 249 | I | Q | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,643 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.241307 | 0.067906 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183968,"numValue":-0.241307379812296,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183969,"numValue":0.0679064944485907,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16913,"numValue":8.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13172 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,172 | train | mutant | 3,797,536 | 225 | 3,801,481 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I249R | I249R | 1 | 1 | 0 | 0 | 249 | I | R | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,644 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.253937 | 0.043886 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183970,"numValue":-0.253936574888535,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183971,"numValue":0.0438859993465076,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16913,"numValue":8.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13173 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,173 | train | mutant | 3,797,537 | 225 | 3,801,482 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I249S | I249S | 1 | 1 | 0 | 0 | 249 | I | S | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,850,782 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.35449 | 0.043709 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9694246,"numValue":0.354489650385594,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9694247,"numValue":0.0437086452477136,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16913,"numValue":8.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13174 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,174 | train | mutant | 3,797,537 | 225 | 3,801,482 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I249S | I249S | 1 | 1 | 0 | 0 | 249 | I | S | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,645 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.626086 | 0.052022 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183972,"numValue":-0.626085900813801,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183973,"numValue":0.0520215975945298,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16913,"numValue":8.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13175 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,175 | train | mutant | 3,797,538 | 225 | 3,801,483 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I249T | I249T | 1 | 1 | 0 | 0 | 249 | I | T | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,850,783 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.169983 | 0.067947 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9694248,"numValue":0.169983068600076,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9694249,"numValue":0.0679472867331415,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16913,"numValue":8.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13176 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,176 | train | mutant | 3,797,538 | 225 | 3,801,483 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I249T | I249T | 1 | 1 | 0 | 0 | 249 | I | T | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,646 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.362651 | 0.061289 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183974,"numValue":-0.362650933133962,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183975,"numValue":0.0612890731288361,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16913,"numValue":8.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13177 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,177 | train | mutant | 3,797,539 | 225 | 3,801,484 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I249V | I249V | 1 | 1 | 0 | 0 | 249 | I | V | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,850,784 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.093649 | 0.10024 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9694250,"numValue":-0.0936486444969714,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9694251,"numValue":0.100240020782403,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16913,"numValue":8.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13179 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,179 | train | mutant | 3,797,540 | 225 | 3,801,485 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I249W | I249W | 1 | 1 | 0 | 0 | 249 | I | W | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,850,785 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.309497 | 0.053398 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9694252,"numValue":0.30949687989727,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9694253,"numValue":0.0533975702630119,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16913,"numValue":8.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13180 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,180 | train | mutant | 3,797,540 | 225 | 3,801,485 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I249W | I249W | 1 | 1 | 0 | 0 | 249 | I | W | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,648 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.630213 | 0.047952 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183978,"numValue":-0.630212509401527,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183979,"numValue":0.0479523503143293,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16913,"numValue":8.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13181 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,181 | train | mutant | 3,797,541 | 225 | 3,801,486 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I249Y | I249Y | 1 | 1 | 0 | 0 | 249 | I | Y | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,850,786 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.090639 | 0.136702 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9694254,"numValue":0.0906385975886807,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9694255,"numValue":0.136701847537722,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16913,"numValue":8.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13182 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,182 | train | mutant | 3,797,541 | 225 | 3,801,486 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I249Y | I249Y | 1 | 1 | 0 | 0 | 249 | I | Y | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,649 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.556097 | 0.080644 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183980,"numValue":-0.556096591747301,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183981,"numValue":0.0806439193077346,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16913,"numValue":8.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13183 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,183 | train | mutant | 4,906,055 | 225 | 4,912,643 | 504 | 503 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | delI249 | delI249 | 1 | 0 | 1 | 0 | 249 | I | - | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,170 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.265238 | 0.103073 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183022,"numValue":-1.26523817277811,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183023,"numValue":0.103072994197354,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16913,"numValue":8.0,"position":249,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13184 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,184 | train | mutant | 3,798,830 | 225 | 3,802,775 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N250A | N250A | 1 | 1 | 0 | 0 | 250 | N | A | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,852,079 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.879547 | 0.119704 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9696840,"numValue":0.879546570061715,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9696841,"numValue":0.119704427398849,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16914,"numValue":6.0,"position":250,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13185 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,185 | train | mutant | 3,798,830 | 225 | 3,802,775 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N250A | N250A | 1 | 1 | 0 | 0 | 250 | N | A | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,179 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.655912 | 0.050578 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183040,"numValue":-0.655912268915698,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183041,"numValue":0.0505777938305626,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16914,"numValue":6.0,"position":250,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13186 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,186 | train | mutant | 3,798,831 | 225 | 3,802,776 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N250C | N250C | 1 | 1 | 0 | 0 | 250 | N | C | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,852,080 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.224276 | 0.093272 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9696842,"numValue":0.224275878371721,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9696843,"numValue":0.0932724181720515,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16914,"numValue":6.0,"position":250,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13187 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,187 | train | mutant | 3,798,831 | 225 | 3,802,776 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N250C | N250C | 1 | 1 | 0 | 0 | 250 | N | C | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,180 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.040788 | 0.066919 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183042,"numValue":-0.0407878760586613,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183043,"numValue":0.0669189871947306,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16914,"numValue":6.0,"position":250,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13188 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,188 | train | mutant | 3,798,832 | 225 | 3,802,777 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N250D | N250D | 1 | 1 | 0 | 0 | 250 | N | D | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,852,081 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.273068 | 0.065607 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9696844,"numValue":0.273067742544174,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9696845,"numValue":0.0656073433131066,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16914,"numValue":6.0,"position":250,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13189 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,189 | train | mutant | 3,798,832 | 225 | 3,802,777 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N250D | N250D | 1 | 1 | 0 | 0 | 250 | N | D | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,181 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.00024 | 0.082478 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183044,"numValue":-0.000240298444621037,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183045,"numValue":0.0824775874058439,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16914,"numValue":6.0,"position":250,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13190 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,190 | train | mutant | 3,798,833 | 225 | 3,802,778 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N250E | N250E | 1 | 1 | 0 | 0 | 250 | N | E | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,852,082 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.497677 | 0.091073 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9696846,"numValue":0.497676906532078,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9696847,"numValue":0.0910729964209077,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16914,"numValue":6.0,"position":250,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13191 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,191 | train | mutant | 3,798,833 | 225 | 3,802,778 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N250E | N250E | 1 | 1 | 0 | 0 | 250 | N | E | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,182 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.710442 | 0.053453 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183046,"numValue":-0.710442033245823,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183047,"numValue":0.0534530363325718,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16914,"numValue":6.0,"position":250,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13192 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,192 | train | mutant | 3,798,834 | 225 | 3,802,779 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N250F | N250F | 1 | 1 | 0 | 0 | 250 | N | F | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,852,083 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 1.091984 | 0.209627 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9696848,"numValue":1.09198410238639,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9696849,"numValue":0.209626930154756,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16914,"numValue":6.0,"position":250,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13193 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,193 | train | mutant | 3,798,834 | 225 | 3,802,779 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N250F | N250F | 1 | 1 | 0 | 0 | 250 | N | F | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,183 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.579048 | 0.09185 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183048,"numValue":-0.57904827596946,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183049,"numValue":0.0918501020052973,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16914,"numValue":6.0,"position":250,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13194 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,194 | train | mutant | 3,798,835 | 225 | 3,802,780 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N250G | N250G | 1 | 1 | 0 | 0 | 250 | N | G | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,852,084 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.912803 | 0.153738 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9696850,"numValue":0.912802663607662,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9696851,"numValue":0.153737921066142,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16914,"numValue":6.0,"position":250,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13195 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,195 | train | mutant | 3,798,835 | 225 | 3,802,780 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N250G | N250G | 1 | 1 | 0 | 0 | 250 | N | G | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,184 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.624849 | 0.042821 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183050,"numValue":-0.624848682100089,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183051,"numValue":0.0428212226159682,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16914,"numValue":6.0,"position":250,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13196 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,196 | train | mutant | 3,798,836 | 225 | 3,802,781 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N250H | N250H | 1 | 1 | 0 | 0 | 250 | N | H | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,852,085 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.230079 | 0.176159 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9696852,"numValue":0.230078860544078,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9696853,"numValue":0.176159171322821,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16914,"numValue":6.0,"position":250,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13197 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,197 | train | mutant | 3,798,836 | 225 | 3,802,781 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N250H | N250H | 1 | 1 | 0 | 0 | 250 | N | H | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,185 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.05958 | 0.105897 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183052,"numValue":0.0595804875323638,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183053,"numValue":0.105897296611864,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16914,"numValue":6.0,"position":250,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13198 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,198 | train | mutant | 3,798,837 | 225 | 3,802,782 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N250I | N250I | 1 | 1 | 0 | 0 | 250 | N | I | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,852,086 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 1.662021 | 0.776185 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9696854,"numValue":1.66202148198077,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9696855,"numValue":0.776185268381016,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16914,"numValue":6.0,"position":250,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13199 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,199 | train | mutant | 3,798,837 | 225 | 3,802,782 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N250I | N250I | 1 | 1 | 0 | 0 | 250 | N | I | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,186 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.957775 | 0.175588 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183054,"numValue":-0.957775095479543,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183055,"numValue":0.175588221848123,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16914,"numValue":6.0,"position":250,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13200 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,200 | train | mutant | 3,798,838 | 225 | 3,802,783 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N250K | N250K | 1 | 1 | 0 | 0 | 250 | N | K | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,852,087 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.847987 | 0.098092 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9696856,"numValue":0.847987129634333,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9696857,"numValue":0.0980918938233722,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16914,"numValue":6.0,"position":250,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13201 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,201 | train | mutant | 3,798,838 | 225 | 3,802,783 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N250K | N250K | 1 | 1 | 0 | 0 | 250 | N | K | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,187 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.781506 | 0.071751 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183056,"numValue":-0.781505762808256,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183057,"numValue":0.0717513889160584,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16914,"numValue":6.0,"position":250,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13202 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,202 | train | mutant | 3,798,839 | 225 | 3,802,784 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N250L | N250L | 1 | 1 | 0 | 0 | 250 | N | L | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,852,088 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 1.256052 | 0.329313 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9696858,"numValue":1.2560524146894,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9696859,"numValue":0.329312992973768,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16914,"numValue":6.0,"position":250,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13203 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,203 | train | mutant | 3,798,839 | 225 | 3,802,784 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N250L | N250L | 1 | 1 | 0 | 0 | 250 | N | L | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,188 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.657868 | 0.050788 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183058,"numValue":-0.657867677616546,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183059,"numValue":0.0507880629265081,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16914,"numValue":6.0,"position":250,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13204 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,204 | train | mutant | 3,798,840 | 225 | 3,802,785 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N250M | N250M | 1 | 1 | 0 | 0 | 250 | N | M | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,852,089 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.900615 | 0.125662 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9696860,"numValue":0.900614749133752,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9696861,"numValue":0.125662439483224,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16914,"numValue":6.0,"position":250,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13206 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,206 | train | mutant | 3,798,841 | 225 | 3,802,786 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N250P | N250P | 1 | 1 | 0 | 0 | 250 | N | P | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,852,090 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 1.071823 | 0.207177 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9696862,"numValue":1.07182333835937,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9696863,"numValue":0.207176946667462,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16914,"numValue":6.0,"position":250,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13207 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,207 | train | mutant | 3,798,841 | 225 | 3,802,786 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N250P | N250P | 1 | 1 | 0 | 0 | 250 | N | P | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,630 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.094234 | 0.078745 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183942,"numValue":-1.09423437579613,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183943,"numValue":0.0787447340774063,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16914,"numValue":6.0,"position":250,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13209 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,209 | train | mutant | 3,798,842 | 225 | 3,802,787 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N250Q | N250Q | 1 | 1 | 0 | 0 | 250 | N | Q | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,631 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.424918 | 0.053164 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183944,"numValue":-0.424918466518925,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183945,"numValue":0.0531642087418004,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16914,"numValue":6.0,"position":250,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13210 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,210 | train | mutant | 3,798,843 | 225 | 3,802,788 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N250R | N250R | 1 | 1 | 0 | 0 | 250 | N | R | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,852,092 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.788268 | 0.089076 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9696866,"numValue":0.78826835171169,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9696867,"numValue":0.0890755265333779,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16914,"numValue":6.0,"position":250,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13211 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,211 | train | mutant | 3,798,843 | 225 | 3,802,788 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N250R | N250R | 1 | 1 | 0 | 0 | 250 | N | R | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,632 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.83796 | 0.044525 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183946,"numValue":-0.837960381335012,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183947,"numValue":0.0445249385883309,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16914,"numValue":6.0,"position":250,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13212 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,212 | train | mutant | 3,798,844 | 225 | 3,802,789 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N250S | N250S | 1 | 1 | 0 | 0 | 250 | N | S | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,852,093 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.352675 | 0.060561 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9696868,"numValue":0.352674955329229,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9696869,"numValue":0.0605605823554103,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16914,"numValue":6.0,"position":250,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13213 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,213 | train | mutant | 3,798,844 | 225 | 3,802,789 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N250S | N250S | 1 | 1 | 0 | 0 | 250 | N | S | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,633 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.039399 | 0.048798 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183948,"numValue":-0.039398600945058,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183949,"numValue":0.048798081485863,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16914,"numValue":6.0,"position":250,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13216 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,216 | train | mutant | 3,798,846 | 225 | 3,802,791 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N250V | N250V | 1 | 1 | 0 | 0 | 250 | N | V | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,852,095 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 1.436154 | 0.143639 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9696872,"numValue":1.43615391666739,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9696873,"numValue":0.143639067571137,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16914,"numValue":6.0,"position":250,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13217 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,217 | train | mutant | 3,798,846 | 225 | 3,802,791 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N250V | N250V | 1 | 1 | 0 | 0 | 250 | N | V | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,635 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.101216 | 0.055091 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183952,"numValue":-1.1012159208716,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183953,"numValue":0.0550909805518472,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16914,"numValue":6.0,"position":250,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13218 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,218 | train | mutant | 3,798,847 | 225 | 3,802,792 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N250W | N250W | 1 | 1 | 0 | 0 | 250 | N | W | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,852,096 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 1.005875 | 0.170015 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9696874,"numValue":1.00587518692909,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9696875,"numValue":0.170015037822696,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16914,"numValue":6.0,"position":250,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13220 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,220 | train | mutant | 3,798,848 | 225 | 3,802,793 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N250Y | N250Y | 1 | 1 | 0 | 0 | 250 | N | Y | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,852,097 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.77629 | 0.20441 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9696876,"numValue":0.776290144535477,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9696877,"numValue":0.204409937869048,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16914,"numValue":6.0,"position":250,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13221 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,221 | train | mutant | 3,798,848 | 225 | 3,802,793 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N250Y | N250Y | 1 | 1 | 0 | 0 | 250 | N | Y | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,637 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.39529 | 0.086528 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183956,"numValue":-0.395290145711288,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183957,"numValue":0.0865277301640069,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16914,"numValue":6.0,"position":250,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13222 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,222 | train | mutant | 4,906,056 | 225 | 4,912,644 | 504 | 503 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | delN250 | delN250 | 1 | 0 | 1 | 0 | 250 | N | - | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,178 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.306962 | 0.09443 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183038,"numValue":-1.30696199536476,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183039,"numValue":0.0944297296790099,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16914,"numValue":6.0,"position":250,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13223 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,223 | train | mutant | 3,800,140 | 225 | 3,804,085 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H251A | H251A | 1 | 1 | 0 | 0 | 251 | H | A | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,853,390 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.098509 | 0.050002 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9699462,"numValue":0.0985085177228109,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9699463,"numValue":0.0500016983860507,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16915,"numValue":8.0,"position":251,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13224 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,224 | train | mutant | 3,800,140 | 225 | 3,804,085 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H251A | H251A | 1 | 1 | 0 | 0 | 251 | H | A | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,191 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.052369 | 0.04816 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183064,"numValue":-0.0523691471230927,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183065,"numValue":0.0481596912702873,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16915,"numValue":8.0,"position":251,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13225 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,225 | train | mutant | 3,800,141 | 225 | 3,804,086 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H251C | H251C | 1 | 1 | 0 | 0 | 251 | H | C | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,853,391 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.130862 | 0.063402 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9699464,"numValue":0.130862327503398,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9699465,"numValue":0.0634017786550185,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16915,"numValue":8.0,"position":251,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13226 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,226 | train | mutant | 3,800,141 | 225 | 3,804,086 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H251C | H251C | 1 | 1 | 0 | 0 | 251 | H | C | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,192 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.237495 | 0.054094 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183066,"numValue":-0.237495227997134,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183067,"numValue":0.0540941398517772,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16915,"numValue":8.0,"position":251,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13228 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,228 | train | mutant | 3,800,142 | 225 | 3,804,087 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H251D | H251D | 1 | 1 | 0 | 0 | 251 | H | D | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,193 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.045196 | 0.06204 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183068,"numValue":-0.0451959998440924,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183069,"numValue":0.0620400137251788,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16915,"numValue":8.0,"position":251,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13229 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,229 | train | mutant | 3,800,143 | 225 | 3,804,088 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H251E | H251E | 1 | 1 | 0 | 0 | 251 | H | E | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,853,393 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.14464 | 0.128331 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9699468,"numValue":0.144639588335257,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9699469,"numValue":0.12833105374359,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16915,"numValue":8.0,"position":251,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13230 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,230 | train | mutant | 3,800,143 | 225 | 3,804,088 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H251E | H251E | 1 | 1 | 0 | 0 | 251 | H | E | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,194 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.064795 | 0.050544 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183070,"numValue":0.0647946455045535,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183071,"numValue":0.0505444066691842,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16915,"numValue":8.0,"position":251,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13231 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,231 | train | mutant | 3,800,144 | 225 | 3,804,089 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H251F | H251F | 1 | 1 | 0 | 0 | 251 | H | F | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,853,394 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.330814 | 0.088798 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9699470,"numValue":0.330813959791252,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9699471,"numValue":0.0887979873194692,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16915,"numValue":8.0,"position":251,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13232 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,232 | train | mutant | 3,800,144 | 225 | 3,804,089 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H251F | H251F | 1 | 1 | 0 | 0 | 251 | H | F | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,195 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.056052 | 0.070928 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183072,"numValue":-0.0560516014333771,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183073,"numValue":0.0709280007257331,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16915,"numValue":8.0,"position":251,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13233 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,233 | train | mutant | 3,800,145 | 225 | 3,804,090 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H251G | H251G | 1 | 1 | 0 | 0 | 251 | H | G | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,853,395 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.198241 | 0.068991 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9699472,"numValue":0.198240676852516,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9699473,"numValue":0.0689905535324498,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16915,"numValue":8.0,"position":251,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13234 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,234 | train | mutant | 3,800,145 | 225 | 3,804,090 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H251G | H251G | 1 | 1 | 0 | 0 | 251 | H | G | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,196 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.233846 | 0.042591 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183074,"numValue":-0.233846192675836,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183075,"numValue":0.0425905042815235,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16915,"numValue":8.0,"position":251,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13235 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,235 | train | mutant | 3,800,146 | 225 | 3,804,091 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H251I | H251I | 1 | 1 | 0 | 0 | 251 | H | I | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,853,396 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.052933 | 0.071105 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9699474,"numValue":0.0529326436926478,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9699475,"numValue":0.0711045856137548,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16915,"numValue":8.0,"position":251,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13236 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,236 | train | mutant | 3,800,146 | 225 | 3,804,091 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H251I | H251I | 1 | 1 | 0 | 0 | 251 | H | I | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,617 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.141887 | 0.091512 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183916,"numValue":-0.141886683266117,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183917,"numValue":0.091512490647507,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16915,"numValue":8.0,"position":251,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13237 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,237 | train | mutant | 3,800,147 | 225 | 3,804,092 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H251K | H251K | 1 | 1 | 0 | 0 | 251 | H | K | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,853,397 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.075479 | 0.071023 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9699476,"numValue":-0.0754788844950006,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9699477,"numValue":0.0710230320255744,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16915,"numValue":8.0,"position":251,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13238 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,238 | train | mutant | 3,800,147 | 225 | 3,804,092 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H251K | H251K | 1 | 1 | 0 | 0 | 251 | H | K | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,618 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.097285 | 0.067774 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183918,"numValue":0.0972850640118654,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183919,"numValue":0.0677744257868749,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16915,"numValue":8.0,"position":251,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13239 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,239 | train | mutant | 3,800,148 | 225 | 3,804,093 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H251L | H251L | 1 | 1 | 0 | 0 | 251 | H | L | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,853,398 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.092237 | 0.070011 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9699478,"numValue":0.0922367616456254,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9699479,"numValue":0.0700112697079877,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16915,"numValue":8.0,"position":251,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13241 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,241 | train | mutant | 3,800,149 | 225 | 3,804,094 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H251M | H251M | 1 | 1 | 0 | 0 | 251 | H | M | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,853,399 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.0331 | 0.079543 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9699480,"numValue":0.0331002241745806,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9699481,"numValue":0.0795426329298562,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16915,"numValue":8.0,"position":251,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13242 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,242 | train | mutant | 3,800,149 | 225 | 3,804,094 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H251M | H251M | 1 | 1 | 0 | 0 | 251 | H | M | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,620 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.079825 | 0.05941 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183922,"numValue":-0.0798252336465738,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183923,"numValue":0.0594095573605974,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16915,"numValue":8.0,"position":251,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13243 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,243 | train | mutant | 3,800,150 | 225 | 3,804,095 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H251N | H251N | 1 | 1 | 0 | 0 | 251 | H | N | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,853,400 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.020378 | 0.140368 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9699482,"numValue":0.020378234635761,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9699483,"numValue":0.140367764259614,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16915,"numValue":8.0,"position":251,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13244 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,244 | train | mutant | 3,800,150 | 225 | 3,804,095 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H251N | H251N | 1 | 1 | 0 | 0 | 251 | H | N | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,621 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.355663 | 0.121049 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183924,"numValue":-0.355663181674818,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183925,"numValue":0.121048590959345,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16915,"numValue":8.0,"position":251,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13249 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,249 | train | mutant | 3,800,153 | 225 | 3,804,098 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H251R | H251R | 1 | 1 | 0 | 0 | 251 | H | R | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,853,403 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.035471 | 0.106419 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9699488,"numValue":0.0354710981832171,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9699489,"numValue":0.106418941207839,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16915,"numValue":8.0,"position":251,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13250 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,250 | train | mutant | 3,800,153 | 225 | 3,804,098 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H251R | H251R | 1 | 1 | 0 | 0 | 251 | H | R | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,624 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.018094 | 0.043367 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183930,"numValue":0.0180939954658309,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183931,"numValue":0.0433672729822119,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16915,"numValue":8.0,"position":251,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13251 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,251 | train | mutant | 3,800,154 | 225 | 3,804,099 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H251S | H251S | 1 | 1 | 0 | 0 | 251 | H | S | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,853,404 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.048827 | 0.071268 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9699490,"numValue":0.0488266038359777,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9699491,"numValue":0.0712682644326743,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16915,"numValue":8.0,"position":251,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13253 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,253 | train | mutant | 3,800,155 | 225 | 3,804,100 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H251T | H251T | 1 | 1 | 0 | 0 | 251 | H | T | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,853,405 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.011047 | 0.079487 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9699492,"numValue":0.0110468214032705,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9699493,"numValue":0.0794874649218239,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16915,"numValue":8.0,"position":251,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13254 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,254 | train | mutant | 3,800,155 | 225 | 3,804,100 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H251T | H251T | 1 | 1 | 0 | 0 | 251 | H | T | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,626 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.191314 | 0.060476 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183934,"numValue":-0.191314163668138,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183935,"numValue":0.0604763312735738,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16915,"numValue":8.0,"position":251,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13255 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,255 | train | mutant | 3,800,156 | 225 | 3,804,101 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H251V | H251V | 1 | 1 | 0 | 0 | 251 | H | V | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,853,406 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.095983 | 0.063398 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9699494,"numValue":0.0959825372830734,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9699495,"numValue":0.0633975284700894,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16915,"numValue":8.0,"position":251,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13256 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,256 | train | mutant | 3,800,156 | 225 | 3,804,101 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H251V | H251V | 1 | 1 | 0 | 0 | 251 | H | V | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,627 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.166297 | 0.046188 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183936,"numValue":-0.166296867650495,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183937,"numValue":0.04618836876516,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16915,"numValue":8.0,"position":251,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13257 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,257 | train | mutant | 3,800,157 | 225 | 3,804,102 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H251W | H251W | 1 | 1 | 0 | 0 | 251 | H | W | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,853,407 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.272263 | 0.074924 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9699496,"numValue":0.272262604255365,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9699497,"numValue":0.0749239478525422,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16915,"numValue":8.0,"position":251,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13258 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,258 | train | mutant | 3,800,157 | 225 | 3,804,102 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H251W | H251W | 1 | 1 | 0 | 0 | 251 | H | W | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,628 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.18853 | 0.050274 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183938,"numValue":-0.188530043609433,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183939,"numValue":0.050274325539854,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16915,"numValue":8.0,"position":251,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13259 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,259 | train | mutant | 3,800,158 | 225 | 3,804,103 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H251Y | H251Y | 1 | 1 | 0 | 0 | 251 | H | Y | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,853,408 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.245251 | 0.077151 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9699498,"numValue":0.245250501612407,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9699499,"numValue":0.0771506351532847,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16915,"numValue":8.0,"position":251,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13260 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,260 | train | mutant | 3,800,158 | 225 | 3,804,103 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H251Y | H251Y | 1 | 1 | 0 | 0 | 251 | H | Y | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,629 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.022797 | 0.096431 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183940,"numValue":0.0227973203206475,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183941,"numValue":0.0964313679812897,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16915,"numValue":8.0,"position":251,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13261 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,261 | train | mutant | 4,906,057 | 225 | 4,912,645 | 504 | 503 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | delH251 | delH251 | 1 | 0 | 1 | 0 | 251 | H | - | 8 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,190 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.195676 | 0.096297 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183062,"numValue":-1.19567563215787,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183063,"numValue":0.0962965780590421,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16915,"numValue":8.0,"position":251,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13262 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,262 | train | mutant | 3,801,449 | 225 | 3,805,394 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K252A | K252A | 1 | 1 | 0 | 0 | 252 | K | A | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,854,701 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.034945 | 0.101075 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9702084,"numValue":-0.0349454976067115,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9702085,"numValue":0.101075215316765,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16916,"numValue":4.0,"position":252,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13263 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,263 | train | mutant | 3,801,449 | 225 | 3,805,394 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K252A | K252A | 1 | 1 | 0 | 0 | 252 | K | A | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,198 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.02099 | 0.048287 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183078,"numValue":-0.0209903078447063,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183079,"numValue":0.0482872006270771,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16916,"numValue":4.0,"position":252,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13264 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,264 | train | mutant | 3,801,450 | 225 | 3,805,395 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K252C | K252C | 1 | 1 | 0 | 0 | 252 | K | C | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,854,702 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.104649 | 0.078519 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9702086,"numValue":0.104648836521609,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9702087,"numValue":0.0785193814970651,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16916,"numValue":4.0,"position":252,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13265 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,265 | train | mutant | 3,801,450 | 225 | 3,805,395 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K252C | K252C | 1 | 1 | 0 | 0 | 252 | K | C | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,199 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.003959 | 0.06783 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183080,"numValue":-0.00395935450474812,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183081,"numValue":0.0678304980762538,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16916,"numValue":4.0,"position":252,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13266 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,266 | train | mutant | 3,801,451 | 225 | 3,805,396 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K252D | K252D | 1 | 1 | 0 | 0 | 252 | K | D | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,854,703 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.033197 | 0.081263 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9702088,"numValue":0.0331972976331723,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9702089,"numValue":0.0812631982617511,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16916,"numValue":4.0,"position":252,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13267 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,267 | train | mutant | 3,801,451 | 225 | 3,805,396 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K252D | K252D | 1 | 1 | 0 | 0 | 252 | K | D | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,200 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.146282 | 0.061358 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183082,"numValue":-0.146282076008125,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183083,"numValue":0.0613575024872381,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16916,"numValue":4.0,"position":252,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13268 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,268 | train | mutant | 3,801,452 | 225 | 3,805,397 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K252E | K252E | 1 | 1 | 0 | 0 | 252 | K | E | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,854,704 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.009612 | 0.070364 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9702090,"numValue":-0.00961154846880623,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9702091,"numValue":0.070363865139735,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16916,"numValue":4.0,"position":252,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13269 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,269 | train | mutant | 3,801,452 | 225 | 3,805,397 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K252E | K252E | 1 | 1 | 0 | 0 | 252 | K | E | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,201 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.032041 | 0.050585 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183084,"numValue":-0.0320408535364151,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183085,"numValue":0.050584931171782,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16916,"numValue":4.0,"position":252,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13270 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,270 | train | mutant | 3,801,453 | 225 | 3,805,398 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K252F | K252F | 1 | 1 | 0 | 0 | 252 | K | F | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,854,705 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.14597 | 0.057831 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9702092,"numValue":0.145969940104035,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9702093,"numValue":0.0578310679074968,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16916,"numValue":4.0,"position":252,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13271 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,271 | train | mutant | 3,801,453 | 225 | 3,805,398 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K252F | K252F | 1 | 1 | 0 | 0 | 252 | K | F | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,202 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.230521 | 0.072737 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183086,"numValue":-0.230521003271627,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183087,"numValue":0.0727374798413376,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16916,"numValue":4.0,"position":252,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13272 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,272 | train | mutant | 3,801,454 | 225 | 3,805,399 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K252G | K252G | 1 | 1 | 0 | 0 | 252 | K | G | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,854,706 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.012387 | 0.091038 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9702094,"numValue":0.0123873625881285,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9702095,"numValue":0.0910380159473285,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16916,"numValue":4.0,"position":252,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13273 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,273 | train | mutant | 3,801,454 | 225 | 3,805,399 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K252G | K252G | 1 | 1 | 0 | 0 | 252 | K | G | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,203 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.029151 | 0.043854 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183088,"numValue":-0.0291509066792515,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183089,"numValue":0.0438537977635479,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16916,"numValue":4.0,"position":252,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13275 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,275 | train | mutant | 3,801,455 | 225 | 3,805,400 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K252H | K252H | 1 | 1 | 0 | 0 | 252 | K | H | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,204 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.01932 | 0.062309 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183090,"numValue":-0.019320154085569,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183091,"numValue":0.0623094901299463,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16916,"numValue":4.0,"position":252,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13276 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,276 | train | mutant | 3,801,456 | 225 | 3,805,401 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K252I | K252I | 1 | 1 | 0 | 0 | 252 | K | I | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,854,708 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.028134 | 0.081682 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9702098,"numValue":0.0281340344350771,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9702099,"numValue":0.0816822685212735,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16916,"numValue":4.0,"position":252,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13277 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,277 | train | mutant | 3,801,456 | 225 | 3,805,401 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K252I | K252I | 1 | 1 | 0 | 0 | 252 | K | I | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,205 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.253369 | 0.085231 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183092,"numValue":-0.253369247765969,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183093,"numValue":0.0852312325293532,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16916,"numValue":4.0,"position":252,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13278 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,278 | train | mutant | 3,801,457 | 225 | 3,805,402 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K252L | K252L | 1 | 1 | 0 | 0 | 252 | K | L | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,854,709 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.023364 | 0.078087 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9702100,"numValue":0.0233635163680068,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9702101,"numValue":0.0780870531811923,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16916,"numValue":4.0,"position":252,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13279 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,279 | train | mutant | 3,801,457 | 225 | 3,805,402 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K252L | K252L | 1 | 1 | 0 | 0 | 252 | K | L | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,606 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.042864 | 0.048691 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183894,"numValue":-0.0428638318269267,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183895,"numValue":0.0486907587898018,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16916,"numValue":4.0,"position":252,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13280 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,280 | train | mutant | 3,801,458 | 225 | 3,805,403 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K252M | K252M | 1 | 1 | 0 | 0 | 252 | K | M | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,854,710 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.067805 | 0.039426 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9702102,"numValue":0.0678052166781073,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9702103,"numValue":0.0394263144268536,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16916,"numValue":4.0,"position":252,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13283 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,283 | train | mutant | 3,801,459 | 225 | 3,805,404 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K252N | K252N | 1 | 1 | 0 | 0 | 252 | K | N | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,608 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.061302 | 0.080983 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183898,"numValue":-0.0613015654651955,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183899,"numValue":0.080983360753017,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16916,"numValue":4.0,"position":252,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] |
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