LiteFold/GO · Datasets at Hugging Face

GO:0070488

70,488

neutrophil aggregation

biological_process

The adhesion of one neutrophil to one or more other neutrophils via adhesion molecules.

[ "GOC:sl", "PMID:12972508" ]

null

[ "neutrocyte aggregation", "neutrophil leucocyte aggregation", "neutrophil leukocyte aggregation", "neutrophilic leucocyte aggregation", "neutrophilic leukocyte aggregation" ]

[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0070486" ]

[]

[ "GO:0070486" ]

[]

null

false

true

7

GO:0070489

70,489

T cell aggregation

biological_process

The adhesion of one T cell to one or more other T cells via adhesion molecules.

[ "GOC:sl", "PMID:12972508" ]

null

[ "T lymphocyte aggregation", "T-cell aggregation", "T-lymphocyte aggregation" ]

[ "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0071593" ]

[]

[ "GO:0071593" ]

[]

null

false

true

5

GO:0070490

70,490

protein pupylation

biological_process

The process in which a Pup protein is conjugated to a target protein via an isopeptide bond between the carboxy-terminus of Pup and the epsilon-amino group of a lysine residue of the target protein.

[ "PMID:18980670" ]

null

[ "Pup-protein conjugation", "pupylation" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0018205", "GO:0032446" ]

[]

[ "GO:0018205", "GO:0032446" ]

[]

null

false

true

3

GO:0070492

70,492

oligosaccharide binding

molecular_function

Binding to an oligosaccharide, a molecule with between two and (about) 20 monosaccharide residues connected by glycosidic linkages.

[ "GOC:mah" ]

null

[]

[ "GO:0030246" ]

[]

[ "GO:0030246" ]

[]

null

false

true

5

GO:0070493

70,493

thrombin-activated receptor signaling pathway

biological_process

A G protein-coupled receptor signaling pathway initiated by thrombin binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process.

[ "GOC:mah", "PMID:1672265" ]

null

[ "thrombin receptor signaling pathway", "thrombin receptor signalling pathway" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0007186" ]

[]

[ "GO:0007186" ]

[]

null

false

true

1

GO:0070495

70,495

negative regulation of thrombin-activated receptor signaling pathway

biological_process

Any process that stops, prevents, or reduces the frequency, rate or extent of thrombin-activated receptor protein signaling pathway activity. A thrombin receptor signaling pathway is the series of molecular signals generated as a consequence of a thrombin-activated receptor binding to one of its physiological ligands.

[ "GOC:mah" ]

null

[ "negative regulation of thrombin receptor signaling pathway", "negative regulation of thrombin receptor signalling pathway" ]

[ "EXACT", "RELATED" ]

[]

[ "GO:0045744", "GO:0070494" ]

[ "negatively_regulates GO:0070493" ]

[ "negatively_regulates" ]

[ "GO:0070493" ]

[ "GO:0045744", "GO:0070493", "GO:0070494" ]

[ "GO:0065007", "negatively_regulates GO:0070493" ]

[]

null

false

true

3

GO:0070496

70,496

positive regulation of thrombin-activated receptor signaling pathway

biological_process

Any process that activates or increases the frequency, rate or extent of thrombin-activated receptor protein signaling pathway activity. A thrombin receptor signaling pathway is the series of molecular signals generated as a consequence of a thrombin-activated receptor binding to one of its physiological ligands.

[ "GOC:mah" ]

null

[ "positive regulation of thrombin receptor signaling pathway", "positive regulation of thrombin receptor signalling pathway" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0045745", "GO:0070494" ]

[ "positively_regulates GO:0070493" ]

[ "positively_regulates" ]

[ "GO:0070493" ]

[ "GO:0045745", "GO:0070493", "GO:0070494" ]

[ "GO:0065007", "positively_regulates GO:0070493" ]

[]

null

false

true

6

GO:0070497

70,497

6-carboxytetrahydropterin synthase activity

molecular_function

Catalysis of the reaction: 7,8-dihydroneopterin 3'-triphosphate + H2O = 6-carboxy-5,6,7,8-tetrahydropterin + triphosphate + acetaldehyde + 2 H+.

[ "PMID:19231875", "RHEA:27966" ]

null

[ "6-carboxy-5,6,7,8-tetrahydropterin synthase activity" ]

[ "EXACT" ]

[]

[ "EC:4.1.2.50", "MetaCyc:RXN0-5507", "RHEA:27966" ]

[ "GO:0016832" ]

[]

[ "GO:0016832" ]

[]

[ "skos:exactMatch EC:4.1.2.50", "skos:exactMatch RHEA:27966", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31104\" xsd:anyURI" ]

null

false

true

7

GO:0070498

70,498

interleukin-1-mediated signaling pathway

biological_process

The series of molecular signals initiated by interleukin-1 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.

[ "GOC:BHF", "GOC:mah", "GOC:signaling" ]

null

[ "IL-1 alpha-mediated signaling pathway", "IL-1 beta-mediated signaling pathway", "IL-1-mediated signaling pathway", "interleukin-1 alpha-mediated signaling pathway", "interleukin-1 beta-mediated signaling pathway", "interleukin-1-mediated signalling pathway" ]

[ "NARROW", "NARROW", "EXACT", "NARROW", "NARROW", "EXACT" ]

[]

[ "Reactome:R-HSA-9020702 \"Interleukin-1 signaling\"" ]

[ "GO:0019221" ]

[ "part_of GO:0071347" ]

[ "part_of" ]

[ "GO:0071347" ]

[ "GO:0019221", "GO:0071347" ]

[]

null

false

true

4

GO:0070499

70,499

exosporium assembly

biological_process

A process that is carried out at the cellular level which results in the formation of an exosporium, the outermost layer of a bacterial endospore.

[ "GOC:mah" ]

null

[ "exosporium formation" ]

[ "EXACT" ]

[]

[ "GO:0022607", "GO:0045229" ]

[]

[ "GO:0022607", "GO:0045229" ]

[]

null

false

true

2

GO:0070500

70,500

obsolete poly-gamma-glutamate metabolic process

biological_process

OBSOLETE. The chemical reactions and pathways involving poly-gamma-glutamate, a polymer of D- and/or L-glutamic acid residues linked by gamma-peptidyl bonds.

[ "GOC:mah", "PMID:16689787" ]

This term was obsoleted because it represents a molecular function.

[ "poly-gamma-glutamate metabolism" ]

[ "EXACT" ]

[]

[ "GO:0034722" ]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24640\" xsd:anyURI" ]

null

true

7

GO:0070501

70,501

poly-gamma-glutamate biosynthetic process

biological_process

The chemical reactions and pathways resulting in the formation of poly-gamma-glutamate, a polymer of D- and/or L-glutamic acid residues linked by gamma-peptidyl bonds.

[ "GOC:mah", "PMID:16689787" ]

null

[ "poly-gamma-glutamate anabolism", "poly-gamma-glutamate biosynthesis", "poly-gamma-glutamate formation", "poly-gamma-glutamate synthesis" ]

[ "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0009059" ]

[]

[ "GO:0009059" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27059\" xsd:anyURI" ]

null

false

true

6

GO:0070502

70,502

capsule poly-gamma-glutamate biosynthetic process

biological_process

The chemical reactions and pathways resulting in the formation of poly-gamma-glutamate, a polymer of D- and/or L-glutamic acid residues linked by gamma-peptidyl bonds, that forms all or part of a bacterial capsule.

[ "GOC:mah", "PMID:16689787" ]

null

[ "capsular poly-gamma-glutamate biosynthetic process", "capsule poly-gamma-glutamate anabolism", "capsule poly-gamma-glutamate biosynthesis", "capsule poly-gamma-glutamate formation", "capsule poly-gamma-glutamate synthesis" ]

[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0045230", "GO:0070501" ]

[]

[ "GO:0045230", "GO:0070501" ]

[]

null

false

true

6

GO:0070503

70,503

obsolete selenium-containing prosthetic group metabolic process

biological_process

OBSOLETE. The chemical reactions and pathways involving a prosthetic group that contains selenium, as in the selenium-dependent molybdenum hydroxylases. The selenium atom in the prosthetic group is required for enzymatic function but is labile to a variety of treatments.

[ "GOC:dh", "GOC:mah" ]

This term was obsoleted because it is an unnecessary grouping class.

[ "selenium-containing prosthetic group metabolism" ]

[ "EXACT" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30524\" xsd:anyURI" ]

null

true

5

GO:0070505

70,505

pollen coat

cellular_component

A layer of extracellular matrix deposited onto the surface of the pollen wall upon disintegration of the tapetal layer of the anther wall in the late stages of pollen development. The composition of this material is highly heterogeneous and includes waxes, lipid droplets, small aromatic molecules, and proteins. The pol...

[ "GOC:mah", "GOC:rph", "PMID:12930826", "PMID:15012271", "PMID:28955324" ]

null

[ "pollenkitt", "tryphine" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0140047" ]

[]

[ "GO:0140047" ]

[]

null

false

true

5

GO:0070506

70,506

high-density lipoprotein particle receptor activity

molecular_function

Combining with a high-density lipoprotein particle and delivering the high-density lipoprotein into the cell via endocytosis.

[ "GOC:bf", "GOC:BHF", "GOC:rl", "PMID:9211901" ]

null

[ "HDL receptor", "high-density lipoprotein receptor activity" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0030228" ]

[ "has_part GO:0008035" ]

[ "has_part" ]

[ "GO:0008035" ]

[ "GO:0008035", "GO:0030228" ]

[]

null

false

true

4

GO:0070507

70,507

regulation of microtubule cytoskeleton organization

biological_process

Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.

[ "GOC:mah" ]

null

[ "regulation of microtubule cytoskeleton organisation", "regulation of microtubule dynamics" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0032886", "GO:0051493" ]

[ "regulates GO:0000226" ]

[ "regulates" ]

[ "GO:0000226" ]

[ "GO:0000226", "GO:0032886", "GO:0051493" ]

[ "GO:0065007", "regulates GO:0000226" ]

[]

null

false

true

3

GO:0070509

70,509

calcium ion import

biological_process

The directed movement of calcium ions into a cell or organelle.

[ "GOC:mah" ]

null

[ "calcium ion uptake", "transmembrane calcium influx" ]

[ "EXACT", "RELATED" ]

[]

[ "GO:0006816" ]

[]

[ "GO:0006816" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23015\" xsd:anyURI" ]

null

false

true

1

GO:0070510

70,510

obsolete regulation of histone H4-K20 methylation

biological_process

OBSOLETE. Any process that modulates the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 20 of histone H4.

[ "GOC:mah" ]

This term was obsoleted because it represents regulation of a molecular function.

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24261\" xsd:anyURI" ]

null

true

7

GO:0070513

70,513

death domain binding

molecular_function

Binding to a death domain of a protein. The death domain (DD) is a homotypic protein interaction module composed of a bundle of six alpha-helices. DD bind each other forming oligomers. Some DD-containing proteins are involved in the regulation of apoptosis and inflammation through their activation of caspases and NF-ka...

[ "GOC:BHF", "GOC:rl", "InterPro:IPR000488", "Pfam:PF00531" ]

For binding to the death effector domain, consider instead the term 'death effector domain binding ; GO:0035877'.

[]

[ "GO:0019904" ]

[]

[ "GO:0019904" ]

[]

null

false

true

5

GO:0070514

70,514

SRF-myogenin-E12 complex

cellular_component

A transcription factor complex that contains the serum response factor (SRF) and the basic helix-loop-helix proteins myogenin and E12, and is involved in activating transcription of muscle-specific genes.

[ "PMID:8617811" ]

null

[]

[ "GO:0090575" ]

[]

[ "GO:0090575" ]

[]

null

false

true

3

GO:0070515

70,515

alphaIIb-beta3 integrin-talin complex

cellular_component

A protein complex that consists of an alphaIIb-beta3 integrin complex bound to talin.

[ "PMID:8663236" ]

null

[ "ITGA2b-ITGB3-TLN1 complex" ]

[ "NARROW" ]

[]

[ "GO:0098797" ]

[]

[ "GO:0098797" ]

[]

null

false

true

2

GO:0070516

70,516

CAK-ERCC2 complex

cellular_component

A protein complex formed by the association of the cyclin-dependent protein kinase activating kinase (CAK) holoenzyme complex with ERCC2.

[ "PMID:8692841", "PMID:8692842" ]

null

[ "cyclin-dependent protein kinase activating kinase holoenzyme-ERCC2 complex" ]

[ "EXACT" ]

[]

[ "GO:0140513" ]

[]

[ "GO:0140513" ]

[]

null

false

true

5

GO:0070517

70,517

DNA replication factor C core complex

cellular_component

A protein complex containing three of the five subunits of eukaryotic replication factor C, those corresponding to human p40, p38, and p37.

[ "PMID:8692848", "PMID:9228079", "PMID:9582326" ]

null

[ "RFC core complex" ]

[ "EXACT" ]

[]

[ "GO:0140513" ]

[ "part_of GO:0043599" ]

[ "part_of" ]

[ "GO:0043599" ]

[ "GO:0043599", "GO:0140513" ]

[]

null

false

true

2

GO:0070518

70,518

alpha4-beta1 integrin-CD53 complex

cellular_component

A protein complex that consists of an alpha4-beta1 integrin complex bound to membrane protein CD53, a member of the tetraspan family.

[ "PMID:8757325" ]

null

[ "ITGA4-ITGB1-CD53 complex" ]

[ "NARROW" ]

[]

[ "GO:0098797" ]

[]

[ "GO:0098797" ]

[]

null

false

true

3

GO:0070519

70,519

alpha4-beta1 integrin-CD63 complex

cellular_component

A protein complex that consists of an alpha4-beta1 integrin complex bound to membrane protein CD63, a member of the tetraspan family.

[ "PMID:8757325" ]

null

[ "ITGA4-ITGB1-CD63 complex" ]

[ "NARROW" ]

[]

[ "GO:0098797" ]

[]

[ "GO:0098797" ]

[]

null

false

true

5

GO:0070520

70,520

alpha4-beta1 integrin-CD81 complex

cellular_component

A protein complex that consists of an alpha4-beta1 integrin complex bound to membrane protein CD81, a member of the tetraspan family.

[ "PMID:10229664", "PMID:8757325" ]

null

[ "ITGA4-ITGB1-CD81 complex" ]

[ "NARROW" ]

[]

[ "GO:0098797" ]

[]

[ "GO:0098797" ]

[]

null

false

true

3

GO:0070521

70,521

alpha4-beta1 integrin-CD82 complex

cellular_component

A protein complex that consists of an alpha4-beta1 integrin complex bound to membrane protein CD82, a member of the tetraspan family.

[ "PMID:8757325" ]

null

[]

[ "GO:0098797" ]

[]

[ "GO:0098797" ]

[]

null

false

true

9

GO:0070522

70,522

ERCC4-ERCC1 complex

cellular_component

A heterodimeric nucleotide-excision repair complex that has endonuclease activity specific for bubble structures characteristic of certain DNA lesions. The subunits are known as XPF/ERCC4 and ERCC1 in mammals, and Rad1p and Rad10p in S. cerevisiae.

[ "PMID:14734547" ]

Note that process and function information are included in the term and definition for the purpose of describing and distinguishing the complex.

[ "Rad1-Rad10 complex", "XPF-ERCC1 complex" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0000109" ]

[]

[ "GO:0000109" ]

[]

null

false

true

7

GO:0070523

70,523

11-beta-hydroxysteroid dehydrogenase (NAD+) activity

molecular_function

Catalysis of the reaction: an 11-beta-hydroxysteroid + NAD+ = an 11-oxosteroid + NADH + H+.

[ "PMID:15761036", "RHEA:53116" ]

null

[]

[ "Reactome:R-HSA-194023 \"HSD11B2,HSD11B1 dimer oxidise CORT to COR\"", "RHEA:42204", "RHEA:50208", "RHEA:53116", "RHEA:69368", "RHEA:69408", "RHEA:84083", "Wikipedia:11beta-hydroxysteroid_dehydrogenase" ]

[ "GO:0033764" ]

[]

[ "GO:0033764" ]

[]

[ "skos:exactMatch RHEA:53116", "skos:narrowMatch RHEA:42204", "skos:narrowMatch RHEA:50208", "skos:narrowMatch RHEA:69368", "skos:narrowMatch RHEA:69408", "skos:narrowMatch RHEA:84083", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21915\" xsd:anyURI" ]

null

false

true

6

GO:0070524

70,524

11-beta-hydroxysteroid dehydrogenase (NADP+) activity

molecular_function

Catalysis of the reaction: an 11-beta-hydroxysteroid + NADP+ = an 11-oxosteroid + NADPH + H+.

[ "PMID:16216911", "RHEA:11388" ]

null

[ "beta-hydroxysteroid dehydrogenase", "corticosteroid 11-beta-dehydrogenase activity" ]

[ "BROAD", "RELATED" ]

[]

[ "EC:1.1.1.146", "MetaCyc:11-BETA-HYDROXYSTEROID-DEHYDROGENASE-RXN", "Reactome:R-HSA-9757706 \"HSD11B1 hydrogenates PREDN to PREDL in hepatic cell\"", "Reactome:R-HSA-9759259 \"HSD11B2 dehydrogenates PREDL to PREDN\"", "RHEA:11388", "RHEA:42200", "RHEA:84079", "Wikipedia:11beta-hydroxysteroid_dehydroge...

[ "GO:0033764" ]

[]

[ "GO:0033764" ]

[]

[ "skos:exactMatch EC:1.1.1.146", "skos:exactMatch MetaCyc:11-BETA-HYDROXYSTEROID-DEHYDROGENASE-RXN", "skos:exactMatch RHEA:11388", "skos:narrowMatch RHEA:42200", "skos:narrowMatch RHEA:84079", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28070\" xsd:anyURI", "term_tracker_item ...

null

false

true

7

GO:0070525

70,525

tRNA threonylcarbamoyladenosine metabolic process

biological_process

The chemical reactions and pathways involving tRNA threonylcarbamoyladenosine, a modified nucleoside found in some tRNA molecules.

[ "GOC:imk", "GOC:mah", "PMID:19287007" ]

null

[ "t6A metabolic process", "t6A metabolism", "threonylcarbamoyladenosine metabolism" ]

[ "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0006399" ]

[]

[ "GO:0006399" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26218\" xsd:anyURI" ]

null

false

true

2

GO:0070527

70,527

platelet aggregation

biological_process

The adhesion of one platelet to one or more other platelets via adhesion molecules.

[ "GOC:BHF", "GOC:vk" ]

null

[ "blood platelet aggregation", "thrombocyte aggregation" ]

[ "EXACT", "RELATED" ]

[]

[ "GO:0034109" ]

[ "part_of GO:0030168" ]

[ "part_of" ]

[ "GO:0030168" ]

[ "GO:0030168", "GO:0034109" ]

[]

null

false

true

1

GO:0070528

70,528

protein kinase C signaling

biological_process

A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.

[ "GOC:BHF", "GOC:mah" ]

null

[ "PKC signal transduction", "PKC signaling cascade", "protein kinase C signal transduction", "protein kinase C signaling cascade", "protein kinase C signalling cascade" ]

[ "EXACT", "RELATED", "EXACT", "RELATED", "RELATED" ]

[]

[ "GO:0035556" ]

[]

[ "GO:0035556" ]

[]

null

false

true

7

GO:0070529

70,529

obsolete L-tryptophan transaminase activity

molecular_function

OBSOLETE. Catalysis of the transfer of an amino group from L-tryptophan to an acceptor, usually a 2-oxo acid.

[ "GOC:mah" ]

This term was obsoleted because it is an unnecessary grouping term.

[ "L-tryptophan aminotransferase activity" ]

[ "EXACT" ]

[]

[ "GO:0047299" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31140\" xsd:anyURI" ]

null

true

1

GO:0070530

70,530

K63-linked polyubiquitin modification-dependent protein binding

molecular_function

Binding to a protein upon poly-ubiquitination formed by linkages between lysine residues at position 63 in the target protein.

[ "GOC:mah", "PMID:15556404", "PMID:17525341" ]

null

[]

[ "GO:0031593" ]

[]

[ "GO:0031593" ]

[]

null

false

true

8

GO:0070531

70,531

BRCA1-A complex

cellular_component

A protein complex that contains the BRCA1-BARD1 heterodimer, RAP80/UIMC1, BRCC3/BRCC36, BRE/BRCC45, FAM175A/CCDC98/Abraxas and MERIT40/NBA1, and specifically recognizes and binds K63-linked polyubiquitin chains present on histone H2A and H2AX at DNA damage sites.

[ "GOC:mah", "PMID:19261749" ]

null

[]

[ "GO:0140513" ]

[]

[ "GO:0140513" ]

[]

null

false

true

2

GO:0070532

70,532

BRCA1-B complex

cellular_component

A protein complex that contains the BRCA1-BARD1 heterodimer, BACH1 and TopBP1, and binds to DNA during S phase at DNA damage sites.

[ "GOC:mah", "PMID:16391231" ]

null

[]

[ "GO:0140513" ]

[]

[ "GO:0140513" ]

[]

null

false

true

9

GO:0070533

70,533

BRCA1-C complex

cellular_component

A protein complex that contains the BRCA1-BARD1 heterodimer, CtIP and Mre11/Rad50/NBS1 (M/R/N) complex, and binds to DNA at DNA damage sites. BRCA1-C binding ta damaged DNA is required for DNA damage-induced Chk1 phosphorylation and the G2/M transition checkpoint.

[ "GOC:mah", "PMID:15485915", "PMID:16391231" ]

null

[]

[ "GO:0140513" ]

[]

[ "GO:0140513" ]

[]

null

false

true

9

GO:0070535

70,535

obsolete histone H2A K63-linked ubiquitination

biological_process

OBSOLETE. A histone ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is added to a lysine residue in histone H2A or the variant H2AX.

[ "GOC:mah", "PMID:18430235" ]

This term was obsoleted because it represents a molecular function.

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24294\" xsd:anyURI" ]

null

true

6

GO:0070536

70,536

protein K63-linked deubiquitination

biological_process

A protein deubiquitination process in which a K63-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is removed from a protein.

[ "GOC:mah", "PMID:19202061", "PMID:19214193" ]

null

[]

[ "GO:0016579" ]

[]

[ "GO:0016579" ]

[]

null

false

true

2

GO:0070537

70,537

obsolete histone H2A K63-linked deubiquitination

biological_process

OBSOLETE. A protein deubiquitination process in which a K63-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is removed from a lysine residue in histone H2A or the variant H2AX.

[ "GOC:mah", "PMID:19202061", "PMID:19214193" ]

This term was obsoleted because it represents a molecular function.

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24294\" xsd:anyURI" ]

null

true

7

GO:0070538

70,538

oleic acid binding

molecular_function

Binding to oleic acid, the 18-carbon monounsaturated fatty acid (9Z)-octadec-9-enoic acid.

[ "GOC:lp", "GOC:mah" ]

null

[]

[ "GO:0036041" ]

[]

[ "GO:0036041" ]

[]

null

false

true

5

GO:0070539

70,539

linoleic acid binding

molecular_function

Binding to linoleic acid, the 18-carbon unsaturated fatty acid (9Z,12Z)-octadeca-9,12-dienoic acid.

[ "GOC:lp", "GOC:mah" ]

null

[]

[ "GO:0036041" ]

[]

[ "GO:0036041" ]

[]

null

false

true

7

GO:0070540

70,540

stearic acid binding

molecular_function

Binding to stearic acid, the 18-carbon saturated fatty acid octadecanoic acid.

[ "GOC:lp", "GOC:mah" ]

null

[]

[ "GO:0036041" ]

[]

[ "GO:0036041" ]

[]

null

false

true

5

GO:0070541

70,541

response to platinum ion

biological_process

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platinum stimulus.

[ "GOC:sl" ]

null

[ "response to platinum" ]

[ "EXACT" ]

[]

[ "GO:0010038" ]

[]

[ "GO:0010038" ]

[]

null

false

true

5

GO:0070542

70,542

response to fatty acid

biological_process

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus.

[ "GOC:lp" ]

null

[]

[ "GO:0033993", "GO:1901700" ]

[]

[ "GO:0033993", "GO:1901700" ]

[]

null

false

true

4

GO:0070543

70,543

response to linoleic acid

biological_process

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a linoleic acid stimulus.

[ "GOC:lp" ]

null

[ "response to linoleate" ]

[ "EXACT" ]

[]

[ "GO:0070542" ]

[]

[ "GO:0070542" ]

[]

null

false

true

8

GO:0070544

70,544

obsolete histone H3-K36 demethylation

biological_process

OBSOLETE. The modification of histone H3 by the removal of a methyl group from lysine at position 36 of the histone.

[ "GOC:sart", "PMID:19061644" ]

This term was obsoleted because it represents a molecular function.

[ "H3K36 demethylation" ]

[ "RELATED" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24294\" xsd:anyURI" ]

null

true

4

GO:0070545

70,545

PeBoW complex

cellular_component

A protein complex that is involved in coordinating ribosome biogenesis with cell cycle progression. In human, it is composed of Pes1, Bop1, and WDR12; in Saccharomyces the proteins are known as Nop7p, Erb1 and Ytm1 respectively.

[ "GOC:ab", "GOC:mah", "PMID:16043514", "PMID:17353269" ]

null

[]

[ "GO:0140513" ]

[ "part_of GO:0005730", "part_of GO:0030686" ]

[ "part_of", "part_of" ]

[ "GO:0005730", "GO:0030686" ]

[ "GO:0005730", "GO:0030686", "GO:0140513" ]

[]

null

false

true

5

GO:0070546

70,546

obsolete L-phenylalanine transaminase activity

molecular_function

OBSOLETE. Catalysis of the transfer of an amino group from L-phenylalanine to an acceptor, usually a 2-oxo acid.

[ "GOC:mah" ]

This term was obsoleted because it is an unnecessary grouping term.

[ "L-phenylalanine aminotransferase activity" ]

[ "EXACT" ]

[]

[ "GO:0047312", "GO:0080130" ]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28070\" xsd:anyURI" ]

null

true

6

GO:0070547

70,547

obsolete L-tyrosine aminotransferase activity

molecular_function

OBSOLETE. Catalysis of the transfer of an amino group from L-tyrosine to an acceptor, usually a 2-oxo acid.

[ "GOC:mah" ]

This term was obsoleted because it is an unnecessary grouping class.

[]

[ "GO:0004838", "GO:0080098" ]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28070\" xsd:anyURI" ]

null

true

2

GO:0070548

70,548

obsolete L-glutamine transaminase activity

molecular_function

OBSOLETE. Catalysis of the transfer of an amino group from L-glutamine to an acceptor, usually a 2-oxo acid.

[ "GOC:mah" ]

This term was obsoleted because it is too general. Consider other glutamine transaminase activity terms.

[ "L-glutamine aminotransferase activity" ]

[ "EXACT" ]

[]

[ "GO:0047945" ]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31140\" xsd:anyURI" ]

null

true

7

GO:0070549

70,549

siRNA-mediated gene silencing by inhibition of translation

biological_process

An siRNA-mediated post-transcriptional gene silencing pathway that blocks the translation of target mRNAs into proteins. Once incorporated into a RNA-induced silencing complex (RISC), an siRNA will typically mediate repression of translation if the siRNA perfectly complements elements located in the 3' untranslated reg...

[ "GOC:mah", "PMID:18771919" ]

null

[ "down regulation of translation involved in RNA interference", "down-regulation of translation involved in RNA interference", "downregulation of translation involved in RNA interference", "inhibition of translation involved in RNA interference", "negative regulation of translation involved in RNA interferen...

[ "BROAD", "BROAD", "BROAD", "BROAD", "BROAD", "EXACT" ]

[]

[ "GO:0017148", "GO:0140766" ]

[]

[ "GO:0017148", "GO:0140766" ]

[]

null

false

true

4

GO:0070550

70,550

rDNA chromatin condensation

biological_process

The process in which the chromatin structure of the rDNA repeats is compacted. In S. cerevisiae, condensation and resolution of the rDNA occurs during anaphase.

[ "GOC:dgf", "PMID:10811823", "PMID:15137940" ]

null

[ "rDNA condensation", "rDNA packaging" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0030261" ]

[ "part_of GO:1990700" ]

[ "part_of" ]

[ "GO:1990700" ]

[ "GO:0030261", "GO:1990700" ]

[]

null

false

true

9

GO:0070551

70,551

endoribonuclease activity, cleaving siRNA-paired mRNA

molecular_function

Catalysis of the endonucleolytic cleavage of the mRNA in a double-stranded RNA molecule formed by the base pairing of an mRNA with an siRNA, yielding 5'-phosphomonoesters.

[ "GOC:mah", "PMID:15105377" ]

null

[ "argonaute endoribonuclease activity" ]

[ "RELATED" ]

[]

[ "Reactome:R-HSA-9820842 \"AGO2:endosiRNA hydrolyzes maternal mRNA in the zygote\"" ]

[ "GO:0016891" ]

[]

[ "GO:0016891" ]

[]

null

false

true

2

GO:0070552

70,552

BRISC complex

cellular_component

A protein complex that contains the FAM175B/ABRO1, BRCC3/BRCC36, BRE/BRCC45 and MERIT40/NBA1 proteins, and specifically cleaves K63-linked polyubiquitin chains.

[ "GOC:mah", "PMID:19214193" ]

null

[]

[ "GO:0140513" ]

[]

[ "GO:0140513" ]

[]

null

false

true

7

GO:0070553

70,553

nicotinic acid receptor activity

molecular_function

Combining with nicotinic acid to initiate a change in cell activity.

[ "GOC:mah", "PMID:12522134" ]

null

[ "niacin receptor activity" ]

[ "EXACT" ]

[]

[ "GO:0004930" ]

[]

[ "GO:0004930" ]

[]

null

false

true

7

GO:0070554

70,554

synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex

cellular_component

A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 3, and a complexin (or orthologs thereof).

[ "PMID:8824312" ]

null

[ "SNARE complex (Stx3, Snap25, Vamp2, Cplx1)", "Stx3-Snap25-Vamp2-Cplx1 complex" ]

[ "NARROW", "NARROW" ]

[]

[ "GO:0031201" ]

[]

[ "GO:0031201" ]

[]

null

false

true

6

GO:0070555

70,555

response to interleukin-1

biological_process

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-1 stimulus.

[ "GOC:BHF", "GOC:mah" ]

null

[ "response to IL-1" ]

[ "EXACT" ]

[]

[ "GO:0034097" ]

[]

[ "GO:0034097" ]

[]

null

false

true

3

GO:0070556

70,556

TAF4B-containing transcription factor TFIID complex

cellular_component

A transcription factor TFIID complex that contains the TBP-associated factor TAF4B (also known as TAFII105 in human), a cell-type-specific variant of TAF4.

[ "GOC:mah", "PMID:8858156" ]

null

[ "TFIID complex, B-cell specific" ]

[ "RELATED" ]

[]

[ "GO:0005669" ]

[]

[ "GO:0005669" ]

[]

null

false

true

7

GO:0070557

70,557

PCNA-p21 complex

cellular_component

A protein complex that contains the cyclin-dependent protein kinase inhibitor p21WAF1/CIP1 bound to PCNA; formation of the complex inhibits DNA replication.

[ "GOC:mah", "PMID:7911228", "PMID:7915843" ]

null

[]

[ "GO:0140513" ]

[]

[ "GO:0140513" ]

[]

null

false

true

8

GO:0070558

70,558

alphaM-beta2 integrin-CD63 complex

cellular_component

A protein complex that consists of an alphaM-beta2 integrin complex bound to membrane protein CD63, a member of the tetraspan family.

[ "PMID:8871662" ]

null

[ "ITGAM-ITGB2-CD63 complex" ]

[ "NARROW" ]

[]

[ "GO:0098797" ]

[]

[ "GO:0098797" ]

[]

null

false

true

3

GO:0070560

70,560

protein secretion by platelet

biological_process

The regulated release of proteins by a platelet or group of platelets.

[ "GOC:BHF", "GOC:mah" ]

null

[]

[ "GO:0009306", "GO:0051649", "GO:0140029" ]

[ "part_of GO:0002576" ]

[ "part_of" ]

[ "GO:0002576" ]

[ "GO:0002576", "GO:0009306", "GO:0051649", "GO:0140029" ]

[]

mah

2009-04-09T02:38:05Z

false

true

5

GO:0070561

70,561

vitamin D receptor signaling pathway

biological_process

A nuclear receptor-mediated signaling pathway initiated by vitamin D binding to an intracellular receptor of the nuclear receptor protein family, and ending with regulation of a downstream cellular process, e.g. transcription.

[ "GOC:BHF", "GOC:mah", "PMID:12637589" ]

null

[ "calcitriol signaling pathway", "intracellular vitamin D receptor signaling pathway", "nuclear receptor-mediated vitamin D signaling pathway", "VDR signaling pathway", "vitamin D receptor signalling pathway" ]

[ "NARROW", "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0009755", "GO:0141193" ]

[ "part_of GO:0071305" ]

[ "part_of" ]

[ "GO:0071305" ]

[ "GO:0009755", "GO:0071305", "GO:0141193" ]

[]

mah

2009-04-14T01:43:59Z

false

true

3

GO:0070562

70,562

regulation of vitamin D receptor signaling pathway

biological_process

Any process that modulates the frequency, rate or extent of vitamin D receptor signaling pathway activity.

[ "GOC:BHF", "GOC:mah" ]

null

[ "regulation of VDR signaling pathway", "regulation of vitamin D receptor signalling pathway" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0032107", "GO:1902531" ]

[ "regulates GO:0070561" ]

[ "regulates" ]

[ "GO:0070561" ]

[ "GO:0032107", "GO:0070561", "GO:1902531" ]

[ "GO:0065007", "regulates GO:0070561" ]

[]

mah

2009-04-14T01:46:03Z

false

true

5

GO:0070563

70,563

negative regulation of vitamin D receptor signaling pathway

biological_process

Any process that stops, prevents, or reduces the frequency, rate or extent of the vitamin D receptor signaling pathway activity.

[ "GOC:BHF", "GOC:mah" ]

null

[ "down regulation of vitamin D receptor signaling pathway", "down-regulation of vitamin D receptor signaling pathway", "downregulation of vitamin D receptor signaling pathway", "inhibition of vitamin D receptor signaling pathway", "negative regulation of VDR signaling pathway", "negative regulation of VDR ...

[ "EXACT", "EXACT", "EXACT", "NARROW", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0070562", "GO:1902532" ]

[ "negatively_regulates GO:0070561" ]

[ "negatively_regulates" ]

[ "GO:0070561" ]

[ "GO:0070561", "GO:0070562", "GO:1902532" ]

[ "GO:0065007", "negatively_regulates GO:0070561" ]

[]

mah

2009-04-14T01:59:21Z

false

true

5

GO:0070564

70,564

positive regulation of vitamin D receptor signaling pathway

biological_process

Any process that activates or increases the frequency, rate or extent of vitamin D receptor signaling pathway activity.

[ "GOC:BHF", "GOC:mah" ]

null

[ "activation of vitamin D receptor signaling pathway", "positive regulation of VDR signaling pathway", "positive regulation of vitamin D receptor signalling pathway", "stimulation of vitamin D receptor signaling pathway", "up regulation of vitamin D receptor signaling pathway", "up-regulation of vitamin D ...

[ "NARROW", "EXACT", "EXACT", "NARROW", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0070562", "GO:1902533" ]

[ "positively_regulates GO:0070561" ]

[ "positively_regulates" ]

[ "GO:0070561" ]

[ "GO:0070561", "GO:0070562", "GO:1902533" ]

[ "GO:0065007", "positively_regulates GO:0070561" ]

[]

mah

2009-04-14T02:02:54Z

false

true

4

GO:0070565

70,565

telomere-telomerase complex

cellular_component

A complex of DNA and protein located at the end of a linear chromosome that enables replication of the telomeric repeat sequences at the end of a linear chromosome.

[ "GOC:pde", "PMID:19179534" ]

Note that this term can be used in place of the obsolete cellular component term 'telomere ; GO:0005696'. Use with caution because this term refers to a specific protein complex and not a region of the chromosome.

[]

[ "GO:0032993" ]

[ "part_of GO:0000781" ]

[ "part_of" ]

[ "GO:0000781" ]

[ "GO:0000781", "GO:0032993" ]

[]

mah

2009-04-14T03:07:50Z

false

true

5

GO:0070566

70,566

adenylyltransferase activity

molecular_function

Catalysis of the transfer of an adenylyl group to an acceptor.

[ "GOC:mah" ]

null

[]

[ "Reactome:R-HSA-9935837 \"The TRAMP:RNA exosome oligoadenylates pre-rRNA 5' external transcribed spacer (5'ETS) fragment\"" ]

[ "GO:0016779" ]

[]

[ "GO:0016779" ]

[]

mah

2009-04-15T11:04:22Z

false

true

5

GO:0070567

70,567

cytidylyltransferase activity

molecular_function

Catalysis of the transfer of a cytidylyl group to an acceptor.

[ "GOC:mah" ]

null

[]

[ "GO:0016779" ]

[]

[ "GO:0016779" ]

[]

mah

2009-04-15T11:05:22Z

false

true

5

GO:0070569

70,569

uridylyltransferase activity

molecular_function

Catalysis of the transfer of an uridylyl group to an acceptor.

[ "GOC:mah" ]

null

[ "uridyl transferase activity", "uridyltransferase activity" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0016779" ]

[]

[ "GO:0016779" ]

[]

mah

2009-04-15T11:06:07Z

false

true

1

GO:0070570

70,570

regulation of neuron projection regeneration

biological_process

Any process that modulates the rate, frequency or extent of neuron projection regeneration, the regrowth of neuronal processes such as axons or dendrites following their loss or damage.

[ "GOC:mah" ]

null

[]

[ "GO:0010975", "GO:0050793", "GO:0080135" ]

[ "regulates GO:0031102" ]

[ "regulates" ]

[ "GO:0031102" ]

[ "GO:0010975", "GO:0031102", "GO:0050793", "GO:0080135" ]

[ "GO:0065007", "regulates GO:0031102" ]

[]

mah

2009-04-15T01:23:48Z

false

true

6

GO:0070571

70,571

negative regulation of neuron projection regeneration

biological_process

Any process that stops, prevents, or reduces the frequency, rate or extent of neuron projection regeneration, the regrowth of neuronal processes such as axons or dendrites following their loss or damage.

[ "GOC:mah" ]

null

[ "growth cone collapse" ]

[ "RELATED" ]

[]

[ "GO:0010977", "GO:0048585", "GO:0051093", "GO:0070570" ]

[ "negatively_regulates GO:0031102" ]

[ "negatively_regulates" ]

[ "GO:0031102" ]

[ "GO:0010977", "GO:0031102", "GO:0048585", "GO:0051093", "GO:0070570" ]

[ "GO:0065007", "negatively_regulates GO:0031102" ]

[]

mah

2009-04-15T01:43:19Z

false

true

4

GO:0070572

70,572

positive regulation of neuron projection regeneration

biological_process

Any process that activates or increases the frequency, rate or extent of neuron projection regeneration, the regrowth of neuronal processes such as axons or dendrites following their loss or damage.

[ "GOC:mah" ]

null

[]

[ "GO:0010976", "GO:0048584", "GO:0051094", "GO:0070570" ]

[ "positively_regulates GO:0031102" ]

[ "positively_regulates" ]

[ "GO:0031102" ]

[ "GO:0010976", "GO:0031102", "GO:0048584", "GO:0051094", "GO:0070570" ]

[ "GO:0065007", "positively_regulates GO:0031102" ]

[]

mah

2009-04-15T01:45:27Z

false

true

6

GO:0070573

70,573

metallodipeptidase activity

molecular_function

Catalysis of the hydrolysis of a dipeptide by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.

[ "GOC:mah", "https://www.ebi.ac.uk/merops/about/glossary.shtml#CATTYPE" ]

null

[ "metallo-exo-dipeptidase activity", "metalloexodipeptidase activity" ]

[ "EXACT", "EXACT" ]

[]

[ "Reactome:R-HSA-2022398 \"ACE:Zn2+ hydrolyzes AGT(25-33) (Angiotensin-(1-9)) to AGT(25-31) (Angiotensin-(1-7))\"", "Reactome:R-HSA-2022405 \"ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8))\"", "Reactome:R-HSA-2065355 \"Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1...

[ "GO:0008235", "GO:0016805" ]

[]

[ "GO:0008235", "GO:0016805" ]

[]

mah

2009-04-15T03:11:29Z

false

true

8

GO:0070574

70,574

cadmium ion transmembrane transport

biological_process

A process in which a cadmium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.

[ "GOC:mah" ]

Note that this term is not intended for use in annotating lateral movement within membranes.

[ "cadmium ion membrane transport", "transmembrane cadmium transport" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0015691", "GO:0098655" ]

[]

[ "GO:0015691", "GO:0098655" ]

[]

mah

2009-04-20T03:31:47Z

false

true

1

GO:0070576

70,576

vitamin D 24-hydroxylase activity

molecular_function

Catalysis of the hydroxylation of C-24 of any form of vitamin D.

[ "GOC:BHF", "GOC:mah", "PMID:15546903" ]

null

[ "calciferol 24-hydroxylase activity", "cholecalciferol 24-hydroxylase activity", "ergocalciferol 24-hydroxylase activity", "vitamin D2 24-hydroxylase activity", "vitamin D3 24-hydroxylase activity" ]

[ "NARROW", "NARROW", "NARROW", "NARROW", "NARROW" ]

[]

[ "EC:1.14.15.16" ]

[ "GO:0008395" ]

[]

[ "GO:0008395" ]

[]

[ "skos:narrowMatch EC:1.14.15.16", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28340\" xsd:anyURI" ]

mah

2009-04-21T02:20:52Z

false

true

6

GO:0070577

70,577

obsolete lysine-acetylated histone binding

molecular_function

OBSOLETE. Binding to a histone in which a lysine residue has been modified by acetylation.

[ "GOC:BHF", "GOC:mah", "GOC:rl", "PMID:17582821" ]

This term was obsoleted because it should be captured as histone reader activity ; GO:0140566 or a child.

[ "acetylated histone residue binding" ]

[ "BROAD" ]

[]

[ "GO:0140566" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27427\" xsd:anyURI" ]

mah

2009-04-21T03:03:35Z

true

8

GO:0070578

70,578

RISC-loading complex

cellular_component

A trimeric protein complex required for the formation of a mature RNA-induced silencing complex (RISC). In humans the complex is composed of the endonuclease Dicer (DICER1), TRBP (TARBP2) and the Argonaute protein Ago2 (EIF2C2/AGO2). Within the complex, Dicer and TRBP are required to process precursor miRNAs (pre-miRNA...

[ "GOC:ab", "GOC:BHF", "GOC:nc", "GOC:rph", "PMID:18178619", "PMID:19820710" ]

null

[ "microRNA loading complex", "miRLC", "RLC" ]

[ "EXACT", "EXACT", "RELATED" ]

[]

[ "GO:1902555" ]

[]

[ "GO:1902555" ]

[]

mah

2009-04-22T01:40:19Z

false

true

8

GO:0070579

70,579

DNA 5-methylcytosine dioxygenase activity

molecular_function

Catalysis of the reaction: 5-methylcytosine (5mC) in DNA + 2-oxoglutarate + O2 = 5-hydroxymethylcytosine (5hmC) in DNA + succinate + CO2. This reaction is the first step in the removal of cytosine methylated on position 5 in double-stranded DNA. This activity can iteratively oxidize 5hmC to 5-formylcytosine (5fC) and t...

[ "EC:1.14.11.80", "PMID:19372391", "PMID:21496894", "PMID:21778364" ]

This reaction removes the methyl group from position 5 of cytosine in DNA via oxidation of the 5-methylcytosine, followed by removal of the oxidised base by the base excision repair system. Do not confuse with oxidative DNA demethylase activity ; GO:0035516, which directly reverses the alkylation on nucleotides in the ...

[ "methylcytosine dioxygenase activity" ]

[ "BROAD" ]

[]

[ "EC:1.14.11.80", "Reactome:R-HSA-5220952 \"TET1,2,3 oxidizes 5-formylcytosine to 5-carboxylcytosine\"", "Reactome:R-HSA-5220990 \"TET1,2,3 oxidizes 5-hydroxymethylcytosine to 5-formylcytosine\"", "Reactome:R-HSA-5221014 \"TET1,2,3 oxidizes 5-methylcytosine to 5-hydroxymethylcytosine\"", "Reactome:R-HSA-9817...

[ "GO:0016706", "GO:0140097" ]

[]

[ "GO:0016706", "GO:0140097" ]

[]

[ "skos:exactMatch EC:1.14.11.80", "skos:narrowMatch RHEA:52636", "skos:narrowMatch RHEA:53828", "skos:narrowMatch RHEA:53832", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23312\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24855\" xsd:any...

mah

2009-04-22T02:29:41Z

false

true

3

GO:0070580

70,580

base J metabolic process

biological_process

The chemical reactions and pathways involving base J (beta-D-glucosyl-hydroxymethyluracil), a hypermodified thymidine residue found in the genome of kinetoplastid parasites. This modified base is localized primarily to repetitive DNA, namely the telomeres, and is implicated in the regulation of antigenic variation. The...

[ "PMID:19114062" ]

null

[ "base J metabolism", "beta-D-glucosyl-HOMedU metabolic process", "beta-D-glucosyl-hydroxymethyluracil metabolism" ]

[ "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0006304" ]

[]

[ "GO:0006304" ]

[]

mah

2009-04-22T02:37:23Z

false

true

9

GO:0070581

70,581

rolling circle DNA replication

biological_process

A DNA-dependent DNA replication process in which a single-stranded DNA molecule is synthesized from a circular duplex template. Replication typically does not cease when one circumference has been replicated, but continues around the circumference several more times, producing a long single strand comprising multimers ...

[ "GOC:cb", "GOC:mah", "ISBN:0198506732" ]

null

[ "rolling circle replication" ]

[ "EXACT" ]

[]

[ "GO:0006261" ]

[]

[ "GO:0006261" ]

[]

mah

2009-04-22T02:53:52Z

false

true

2

GO:0070582

70,582

theta DNA replication

biological_process

A DNA-dependent DNA replication process in which a double-stranded DNA molecule is synthesized from a circular duplex template.

[ "GOC:cb", "GOC:mah", "ISBN:0198506732" ]

null

[ "theta replication" ]

[ "EXACT" ]

[]

[ "GO:0006261" ]

[]

[ "GO:0006261" ]

[]

mah

2009-04-22T02:54:50Z

false

true

9

GO:0070583

70,583

spore membrane bending pathway

biological_process

The process in which a bending force is generated in the prospore membrane to form the characteristic curved shape of the prospore.

[ "GOC:dgf", "PMID:18756268" ]

null

[ "ascospore-type prospore membrane bending", "forespore membrane bending", "FSM bending" ]

[ "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0061024", "GO:1903046" ]

[ "part_of GO:0032120" ]

[ "part_of" ]

[ "GO:0032120" ]

[ "GO:0032120", "GO:0061024", "GO:1903046" ]

[]

mah

2009-04-24T10:48:09Z

false

true

6

GO:0070584

70,584

obsolete mitochondrion morphogenesis

biological_process

OBSOLETE. The process in which the anatomical structures of a mitochondrion are generated and organized.

[ "GOC:mah" ]

This term is obsoleted because it is an unnecessary grouping term.

[]

[ "GO:0007005" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26187\" xsd:anyURI" ]

mah

2009-04-24T10:54:19Z

true

4

GO:0070585

70,585

protein localization to mitochondrion

biological_process

A process in which a protein is transported to, or maintained in, a location within the mitochondrion.

[ "GOC:ecd" ]

null

[ "protein localisation in mitochondrion", "protein localization in mitochondrion" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0033365" ]

[]

[ "GO:0033365" ]

[]

mah

2009-04-24T02:31:18Z

false

true

9

GO:0070586

70,586

cell-cell adhesion involved in gastrulation

biological_process

The attachment of one cell to another cell affecting gastrulation.

[ "GOC:dsf", "PMID:19091770" ]

null

[]

[ "GO:0098609" ]

[ "part_of GO:0007369" ]

[ "part_of" ]

[ "GO:0007369" ]

[ "GO:0007369", "GO:0098609" ]

[ "GO:0098609", "part_of GO:0007369" ]

[]

mah

2009-04-24T02:48:23Z

false

true

3

GO:0070587

70,587

regulation of cell-cell adhesion involved in gastrulation

biological_process

Any process that modulates the frequency, rate, or extent of attachment of a cell to another cell affecting gastrulation.

[ "GOC:dsf", "PMID:19091770" ]

null

[]

[ "GO:0022407" ]

[ "regulates GO:0070586" ]

[ "regulates" ]

[ "GO:0070586" ]

[ "GO:0022407", "GO:0070586" ]

[ "GO:0065007", "regulates GO:0070586" ]

[]

mah

2009-04-24T02:51:07Z

false

true

4

GO:0070588

70,588

calcium ion transmembrane transport

biological_process

A process in which a calcium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.

[ "GOC:mah" ]

Note that this term is not intended for use in annotating lateral movement within membranes.

[ "calcium ion membrane transport", "transmembrane calcium transport" ]

[ "EXACT", "EXACT" ]

[]

[ "Reactome:R-HSA-3295583 \"TRP channels\"", "Reactome:R-HSA-425561 \"Sodium/Calcium exchangers\"" ]

[ "GO:0006816", "GO:0098655" ]

[]

[ "GO:0006816", "GO:0098655" ]

[]

mah

2009-04-28T10:44:09Z

false

true

6

GO:0070589

70,589

obsolete cellular component macromolecule biosynthetic process

biological_process

OBSOLETE. The chemical reactions and pathways resulting in the formation of a macromolecule that is destined to form part of a specific cellular component.

[ "GOC:mah" ]

This term was obsoleted because it is an unnecessary grouping class.

[ "cellular component macromolecule biosynthesis" ]

[ "EXACT" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/17904\" xsd:anyURI" ]

mah

2009-04-28T11:01:25Z

true

9

GO:0070590

70,590

spore wall biogenesis

biological_process

A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a spore wall. A spore wall is the specialized cell wall lying outside the cell membrane of a spore.

[ "GOC:mah" ]

null

[]

[ "GO:0042546" ]

[ "part_of GO:0030435" ]

[ "part_of" ]

[ "GO:0030435" ]

[ "GO:0030435", "GO:0042546" ]

[]

mah

2009-04-28T01:06:10Z

false

true

6

GO:0070592

70,592

cell wall polysaccharide biosynthetic process

biological_process

The chemical reactions and pathways resulting in the formation of a polysaccharide destined to form part of a cell wall.

[ "GOC:mah" ]

null

[ "cell wall polysaccharide anabolism", "cell wall polysaccharide biosynthesis", "cell wall polysaccharide synthesis" ]

[ "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0000271", "GO:0010383", "GO:0044038" ]

[]

[ "GO:0000271", "GO:0010383", "GO:0044038" ]

[]

mah

2009-04-28T01:25:54Z

false

true

9

GO:0070593

70,593

dendrite self-avoidance

biological_process

The process in which dendrites recognize and avoid contact with sister dendrites from the same cell.

[ "GOC:sart", "PMID:17482551" ]

null

[ "dendrite repulsion" ]

[ "EXACT" ]

[]

[ "GO:0008038" ]

[]

[ "GO:0008038" ]

[]

mah

2009-04-28T03:29:14Z

false

true

1

GO:0070595

70,595

(1->3)-alpha-glucan metabolic process

biological_process

The chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds.

[ "GOC:mah" ]

null

[ "1,3-alpha-glucan metabolic process", "1,3-alpha-glucan metabolism", "alpha-1,3 glucan metabolic process", "alpha-1,3 glucan metabolism" ]

[ "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0030978" ]

[]

[ "GO:0030978" ]

[]

mah

2009-04-28T03:35:03Z

false

true

9

GO:0070596

70,596

(1->3)-alpha-glucan biosynthetic process

biological_process

The chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds.

[ "GOC:mah" ]

null

[ "1,3-alpha-glucan anabolism", "1,3-alpha-glucan biosynthesis", "1,3-alpha-glucan biosynthetic process", "1,3-alpha-glucan formation", "1,3-alpha-glucan synthesis", "alpha-1,3 glucan anabolism", "alpha-1,3 glucan biosynthesis", "alpha-1,3 glucan biosynthetic process", "alpha-1,3 glucan formation", ...

[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0030979", "GO:0070595" ]

[]

[ "GO:0030979", "GO:0070595" ]

[]

mah

2009-04-28T03:39:24Z

false

true

6

GO:0070597

70,597

cell wall (1->3)-alpha-glucan metabolic process

biological_process

The chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of cells.

[ "GOC:mah" ]

null

[ "cell wall 1,3-alpha-glucan metabolic process", "cell wall 1,3-alpha-glucan metabolism", "cell wall alpha-1,3 glucan metabolic process", "cell wall alpha-1,3 glucan metabolism" ]

[ "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0010383", "GO:0070595" ]

[]

[ "GO:0010383", "GO:0070595" ]

[]

mah

2009-04-28T04:03:00Z

false

true

8

GO:0070599

70,599

fungal-type cell wall (1->3)-alpha-glucan metabolic process

biological_process

The chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of ascospores.

[ "GOC:mah" ]

null

[ "ascospore wall 1,3-alpha-glucan metabolic process", "ascospore wall 1,3-alpha-glucan metabolism", "ascospore wall alpha-1,3 glucan metabolic process", "ascospore wall alpha-1,3 glucan metabolism" ]

[ "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0070597", "GO:0071966" ]

[]

[ "GO:0070597", "GO:0071966" ]

[]

mah

2009-04-28T04:07:23Z

false

true

6

GO:0070600

70,600

fungal-type cell wall (1->3)-alpha-glucan biosynthetic process

biological_process

The chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in fungal-type cell walls, including those of ascospores.

[ "GOC:mah" ]

null

[ "fungal-type cell wall 1,3-alpha-glucan anabolism", "fungal-type cell wall 1,3-alpha-glucan biosynthesis", "fungal-type cell wall 1,3-alpha-glucan biosynthetic process", "fungal-type cell wall 1,3-alpha-glucan formation", "fungal-type cell wall 1,3-alpha-glucan synthesis", "fungal-type cell wall alpha-1,3...

[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0051278", "GO:0070598", "GO:0070599" ]

[]

[ "GO:0051278", "GO:0070598", "GO:0070599" ]

[]

mah

2009-04-28T04:09:48Z

false

true

7

GO:0070601

70,601

centromeric sister chromatid cohesion

biological_process

The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the length of the centromeric region of the chromosome.

[ "GOC:mah" ]

null

[ "sister chromatid cohesion at centromere" ]

[ "EXACT" ]

[]

[ "GO:0007062" ]

[]

[ "GO:0007062" ]

[]

mah

2009-04-28T04:31:00Z

false

true

5