LiteFold/GO · Datasets at Hugging Face

GO:0000513

513

actin severing activator activity

molecular_function

Binds to and increases the activity of a actin severing protein.

[ "PMID:25451933" ]

null

[]

[ "GO:0140677" ]

[]

[ "GO:0140677" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/18437\" xsd:anyURI" ]

pg

2022-03-18T08:10:20Z

false

true

2

GO:0000514

514

3-sulfino-L-alanine: proton, glutamate antiporter activity

molecular_function

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 3-sulfino-L-alanine (cysteinesulfinate) (out) + H+(in) + L-glutamate(in) = 3-sulfino-L-alanine(in) + H+(out) + L-glutamate(out).

[ "PMID:11566871", "RHEA:70967" ]

null

[]

[ "RHEA:70967" ]

[ "GO:0000099", "GO:0015078", "GO:0015175", "GO:0015179", "GO:0072349", "GO:0140848" ]

[]

[ "GO:0000099", "GO:0015078", "GO:0015175", "GO:0015179", "GO:0072349", "GO:0140848" ]

[]

[ "skos:exactMatch RHEA:70967", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23042\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]

pg

2022-03-21T17:18:20Z

false

true

5

GO:0000515

515

aspartate:glutamate, proton antiporter activity

molecular_function

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + L-aspartate(in) + L-glutamate(out) = H+(in) + L-aspartate(out) + L-glutamate(in).

[ "PMID:11566871", "RHEA:70783" ]

null

[ "aspartate:glutamate antiporter activity" ]

[ "RELATED" ]

[]

[ "RHEA:70783" ]

[ "GO:0015183", "GO:0106421" ]

[]

[ "GO:0015183", "GO:0106421" ]

[]

[ "skos:exactMatch RHEA:70783", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23041\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]

pg

2022-03-21T17:33:23Z

false

true

6

GO:0000578

578

embryonic axis specification

biological_process

The establishment, maintenance and elaboration of a pattern along a line or a point in an embryo.

[ "GOC:curators", "GOC:dph", "GOC:sdb_2009", "GOC:tb" ]

null

[ "embryonic axis determination" ]

[ "RELATED" ]

[]

[ "GO:0009798", "GO:0009880" ]

[]

[ "GO:0009798", "GO:0009880" ]

[]

null

false

true

4

GO:0000700

700

mismatch base pair DNA N-glycosylase activity

molecular_function

Catalysis of the removal of single bases present in mismatches by the cleavage the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site.

[ "GOC:elh", "PMID:9224623" ]

null

[]

[ "GO:0019104" ]

[]

[ "GO:0019104" ]

[]

null

false

true

8

GO:0000701

701

purine-specific mismatch base pair DNA N-glycosylase activity

molecular_function

Catalysis of the removal of purines present in mismatches, especially opposite oxidized purines, by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic (AP) site.

[ "GOC:elh", "PMID:9224623" ]

null

[ "A/G-specific adenine DNA glycosylase activity" ]

[ "NARROW" ]

[]

[ "EC:3.2.2.31" ]

[ "GO:0000700" ]

[]

[ "GO:0000700" ]

[]

[ "skos:exactMatch EC:3.2.2.31", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]

null

false

true

8

GO:0000702

702

oxidized base lesion DNA N-glycosylase activity

molecular_function

Catalysis of the removal of oxidized bases by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site.

[ "GOC:elh", "PMID:11554296" ]

null

[]

[ "GO:0019104" ]

[]

[ "GO:0019104" ]

[]

null

false

true

8

GO:0000703

703

oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity

molecular_function

Catalysis of the removal oxidized pyrimidine bases by cleaving the N-C1' glycosidic bond between the oxidized pyrimidine and the deoxyribose sugar. The reaction involves formation of a covalent enzyme-pyrimidine base intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination me...

[ "GOC:elh", "PMID:11554296" ]

Consider also annotating to the molecular function term 'DNA-(apurinic or apyrimidinic site) lyase activity ; GO:0003906'.

[ "bifunctional DNA glycosylase", "DNA glycosylase/AP-lyase", "DNA glycosylase/beta-lyase", "endodeoxyribonuclease III", "endonuclease III", "endonuclease VIII activity", "oxidized pyrimidine base lesion DNA N-glycosylase activity", "pyrimidine-specific oxidized base lesion DNA N-glycosylase activity" ]

[ "BROAD", "BROAD", "BROAD", "RELATED", "RELATED", "RELATED", "EXACT", "RELATED" ]

[ "GO:0019004" ]

[]

[ "Reactome:R-HSA-110224 \"Cleavage of thymine glycol by NTHL1 glycosylase\"", "Reactome:R-HSA-110226 \"Cleavage of cytosine glycol by NTHL1 glycosylase\"", "Reactome:R-HSA-110227 \"Cleavage of dihydrouracil by NTHL1 glycosylase\"" ]

[ "GO:0000702" ]

[]

[ "GO:0000702" ]

[]

null

false

true

5

GO:0000704

704

pyrimidine dimer DNA N-glycosylase activity

molecular_function

Catalysis of the removal of pyrimidine dimers by removing the 5' pyrimidine of the dimer by cleaving the N-C1' glycosidic bond between the 5' pyrimidine of the dimer and the deoxyribose sugar. The reaction releases the 5' pyrimidine of the dimer and leaves an apurinic (AP) site. The reaction involves the formation of a...

[ "GOC:elh", "PMID:9224623" ]

null

[]

[ "GO:0019104" ]

[]

[ "GO:0019104" ]

[]

null

false

true

1

GO:0000705

705

achiasmate meiosis I

biological_process

The first division of meiosis in which homologous chromosomes are paired and segregated from each other, occurring in the constitutive absence of chiasmata.

[ "GOC:elh", "GOC:sart", "PMID:10690419" ]

null

[ "achiasmate meiosis I nuclear division" ]

[ "EXACT" ]

[]

[ "GO:0007127" ]

[]

[ "GO:0007127" ]

[]

null

false

true

5

GO:0000706

706

meiotic DNA double-strand break processing

biological_process

The cell cycle process in which the 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang occurs. This takes place during meiosis.

[ "GOC:elh", "PMID:9334324" ]

null

[]

[ "GO:0000729", "GO:1903046" ]

[]

[ "GO:0000729", "GO:1903046" ]

[ "GO:0000729", "part_of GO:0051321" ]

[]

null

false

true

3

GO:0000707

707

meiotic DNA recombinase assembly

biological_process

During meiosis, the aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form higher order oligomers on single-stranded DNA.

[ "GOC:elh", "PMID:11459983" ]

null

[]

[ "GO:0000730", "GO:0061982" ]

[]

[ "GO:0000730", "GO:0061982" ]

[]

null

false

true

2

GO:0000708

708

meiotic strand invasion

biological_process

The cell cycle process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in wh...

[ "GOC:elh", "PMID:10915877" ]

null

[ "meiotic D-loop biosynthesis", "meiotic D-loop formation", "meiotic displacement loop biosynthesis", "meiotic displacement loop formation" ]

[ "RELATED", "RELATED", "RELATED", "RELATED" ]

[]

[ "GO:0042148", "GO:0061982" ]

[]

[ "GO:0042148", "GO:0061982" ]

[ "GO:0042148", "part_of GO:0051321" ]

[]

null

false

true

1

GO:0000709

709

meiotic joint molecule formation

biological_process

The conversion of the paired broken DNA and homologous duplex DNA into a four-stranded branched intermediate, known as a joint molecule, formed during meiotic recombination. These joint molecules contain Holliday junctions on either side of heteroduplex DNA.

[ "GOC:elh", "PMID:8521495" ]

null

[]

[ "GO:1903046" ]

[ "part_of GO:0007131" ]

[ "part_of" ]

[ "GO:0007131" ]

[ "GO:0007131", "GO:1903046" ]

[]

null

false

true

2

GO:0000711

711

meiotic DNA repair synthesis

biological_process

During meiosis, the synthesis of DNA proceeding from the broken 3' single-strand DNA end that uses the homologous intact duplex as the template.

[ "GOC:elh", "PMID:9334324" ]

null

[]

[ "GO:0000731", "GO:0061982" ]

[]

[ "GO:0000731", "GO:0061982" ]

[]

null

false

true

1

GO:0000712

712

resolution of meiotic recombination intermediates

biological_process

The cleavage and rejoining of intermediates, such as Holliday junctions, formed during meiotic recombination to produce two intact molecules in which genetic material has been exchanged.

[ "GOC:elh", "PMID:11733053" ]

null

[ "resolution of meiotic joint molecules as recombinants" ]

[ "NARROW" ]

[]

[ "GO:0061982" ]

[ "part_of GO:0007131" ]

[ "part_of" ]

[ "GO:0007131" ]

[ "GO:0007131", "GO:0061982" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24138\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25628\" xsd:anyURI" ]

null

false

true

7

GO:0000713

713

meiotic heteroduplex formation

biological_process

During meiosis, the formation of a stable duplex DNA that contains one strand from each of the two recombining DNA molecules.

[ "GOC:elh", "PMID:9334324" ]

null

[]

[ "GO:0061982" ]

[ "part_of GO:0006310" ]

[ "part_of" ]

[ "GO:0006310" ]

[ "GO:0006310", "GO:0061982" ]

[]

null

false

true

9

GO:0000714

714

meiotic strand displacement

biological_process

The cell cycle process in which the broken 3' single-strand DNA molecule that formed heteroduplex DNA with its complement in an intact duplex DNA is rejected. The Watson-Crick base pairing in the original duplex is restored. The rejected 3' single-strand DNA molecule reanneals with its original complement to reform two...

[ "GOC:elh", "PMID:10357855" ]

null

[ "meiotic D-loop dissociation", "meiotic D-loop processing", "meiotic displacement loop dissociation", "meiotic displacement loop processing" ]

[ "RELATED", "RELATED", "RELATED", "RELATED" ]

[]

[ "GO:0000732", "GO:0061982" ]

[]

[ "GO:0000732", "GO:0061982" ]

[]

null

false

true

4

GO:0000715

715

nucleotide-excision repair, DNA damage recognition

biological_process

The identification of lesions in DNA, such as pyrimidine-dimers, intrastrand cross-links, and bulky adducts. The wide range of substrate specificity suggests the repair complex recognizes distortions in the DNA helix.

[ "GOC:elh", "PMID:10197977" ]

null

[ "pyrimidine-dimer repair, DNA damage recognition" ]

[ "RELATED" ]

[]

[ "Reactome:R-HSA-5696394 \"DNA Damage Recognition in GG-NER\"" ]

[ "GO:0051276" ]

[ "part_of GO:0006289" ]

[ "part_of" ]

[ "GO:0006289" ]

[ "GO:0006289", "GO:0051276" ]

[]

null

false

true

6

GO:0000716

716

transcription-coupled nucleotide-excision repair, DNA damage recognition

biological_process

The identification of lesions on the actively transcribed strand of the DNA duplex as well as a small subset of lesions not recognized by the general nucleotide-excision repair pathway.

[ "GOC:elh", "PMID:10197977" ]

null

[ "pyrimidine-dimer repair, DNA damage recognition" ]

[ "RELATED" ]

[]

[ "GO:0000715" ]

[ "part_of GO:0006283" ]

[ "part_of" ]

[ "GO:0006283" ]

[ "GO:0000715", "GO:0006283" ]

[]

null

false

true

8

GO:0000718

718

obsolete nucleotide-excision repair, DNA damage removal

biological_process

OBSOLETE. The removal of the oligonucleotide that contains the DNA damage. The oligonucleotide is formed by dual incisions that flank the site of DNA damage.

[ "GOC:elh", "PMID:10197977" ]

The reason for obsoletion is that this term represents a molecular function.

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29220\" xsd:anyURI" ]

null

true

3

GO:0000719

719

photoreactive repair

biological_process

The repair of UV-induced T-T, C-T and C-C dimers by directly reversing the damage to restore the original pyrimidines.

[ "GOC:elh", "PMID:10915863" ]

null

[ "pyrimidine-dimer repair by photolyase" ]

[ "NARROW" ]

[]

[ "GO:0006290" ]

[]

[ "GO:0006290" ]

[]

null

false

true

4

GO:0000720

720

pyrimidine dimer repair by nucleotide-excision repair

biological_process

The repair of UV-induced T-T, C-T, and C-C dimers by the recognition and removal of the damaged DNA strand from the DNA helix as an oligonucleotide. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase.

[ "GOC:elh" ]

Note that the repair of pyrimidine dimers by nucleotide excision repair involves the same gene products that are involved in general nucleotide excision repair. Consider also annotating to other children of the biological process term 'nucleotide-excision repair ; GO:0006289'.

[]

[ "GO:0006289", "GO:0006290" ]

[]

[ "GO:0006289", "GO:0006290" ]

[]

null

false

true

2

GO:0000721

721

(R,R)-butanediol dehydrogenase activity

molecular_function

Catalysis of the reversible reaction: (R,R)-butane-2,3-diol + NAD+ = (R)-acetoin + NADH + H+.

[ "EC:1.1.1.4" ]

null

[ "(R)-2,3-butanediol dehydrogenase activity", "(R)-diacetyl reductase activity", "1-amino-2-propanol dehydrogenase activity", "1-amino-2-propanol oxidoreductase activity", "2,3-butanediol dehydrogenase activity", "aminopropanol oxidoreductase activity", "butylene glycol dehydrogenase activity", "butyle...

[ "RELATED", "RELATED", "RELATED", "RELATED", "RELATED", "RELATED", "RELATED", "RELATED", "RELATED", "RELATED", "RELATED", "RELATED", "RELATED", "RELATED" ]

[]

[ "EC:1.1.1.4", "MetaCyc:RR-BUTANEDIOL-DEHYDROGENASE-RXN", "RHEA:24340" ]

[ "GO:0016616" ]

[]

[ "GO:0016616" ]

[]

[ "skos:exactMatch EC:1.1.1.4", "skos:exactMatch RHEA:24340", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]

null

false

true

7

GO:0000722

722

telomere maintenance via recombination

biological_process

Any recombinational process that contributes to the maintenance of proper telomeric length.

[ "GOC:elh", "PMID:11850777" ]

null

[ "telomerase-independent telomere maintenance" ]

[ "RELATED" ]

[]

[ "GO:0000723", "GO:0006312" ]

[]

[ "GO:0000723", "GO:0006312" ]

[]

null

false

true

4

GO:0000724

724

double-strand break repair via homologous recombination

biological_process

The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchan...

[ "GOC:elh", "PMID:10357855" ]

null

[ "HDR", "homologous recombinational repair", "homology-directed repair", "HRR", "Rad51-dependent recombinational repair", "Rhp51-dependent recombinational repair" ]

[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]

[ "GO:0016924" ]

[]

[ "Reactome:R-HSA-5693538 \"Homology Directed Repair\"" ]

[ "GO:0000725", "GO:0006302" ]

[]

[ "GO:0000725", "GO:0006302" ]

[]

null

false

true

6

GO:0000726

726

obsolete non-recombinational repair

biological_process

OBSOLETE. A DNA repair process in which that does not require the exchange of genetic material between the broken DNA molecule and a homologous DNA region.

[ "GOC:elh" ]

This term was obsoleted because it was defined negatively, and it represents an unnecessary grouping class.

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/18901\" xsd:anyURI" ]

null

true

1

GO:0000727

727

double-strand break repair via break-induced replication

biological_process

The error-free repair of a double-strand break in DNA in which the centromere-proximal end of a broken chromosome searches for a homologous region in an intact chromosome. DNA synthesis initiates from the 3' end of the invading DNA strand, using the intact chromosome as the template, and progresses to the end of the ch...

[ "GOC:elh", "PMID:10357855" ]

null

[]

[ "GO:0000724" ]

[]

[ "GO:0000724" ]

[]

null

false

true

7

GO:0000729

729

DNA double-strand break processing

biological_process

The 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang.

[ "PMID:10357855" ]

null

[]

[ "GO:0006259" ]

[ "has_part GO:0035312", "part_of GO:0006302" ]

[ "has_part", "part_of" ]

[ "GO:0035312", "GO:0006302" ]

[ "GO:0006259", "GO:0006302", "GO:0035312" ]

[]

null

false

true

6

GO:0000730

730

DNA recombinase assembly

biological_process

The aggregation, arrangement and bonding together of strand exchange proteins (recombinases) into higher order oligomers on single-stranded DNA.

[ "PMID:10357855" ]

null

[ "Rad51 nucleoprotein filament formation" ]

[ "EXACT" ]

[]

[ "GO:0065004", "GO:0090735" ]

[ "part_of GO:0045003" ]

[ "part_of" ]

[ "GO:0045003" ]

[ "GO:0045003", "GO:0065004", "GO:0090735" ]

[]

null

false

true

1

GO:0000732

732

DNA strand displacement

biological_process

The rejection of the broken 3' single-strand DNA molecule that formed heteroduplex DNA with its complement in an intact duplex DNA. The Watson-Crick base pairing in the original duplex is restored. The rejected 3' single-strand DNA molecule reanneals with its original complement to reform two intact duplex molecules.

[ "PMID:10357855" ]

null

[ "D-loop dissociation", "D-loop processing", "displacement loop dissociation", "displacement loop processing", "strand displacement" ]

[ "RELATED", "RELATED", "RELATED", "RELATED", "EXACT" ]

[]

[ "GO:0006259" ]

[ "part_of GO:0006310" ]

[ "part_of" ]

[ "GO:0006310" ]

[ "GO:0006259", "GO:0006310" ]

[]

null

false

true

5

GO:0000735

735

removal of nonhomologous ends

biological_process

The removal of nonhomologous sequences at the broken 3' single-strand DNA end before DNA repair synthesis can occur.

[ "PMID:10357855" ]

null

[]

[ "GO:0006259" ]

[ "has_part GO:0004520" ]

[ "has_part" ]

[ "GO:0004520" ]

[ "GO:0004520", "GO:0006259" ]

[]

null

false

true

4

GO:0000736

736

double-strand break repair via single-strand annealing, removal of nonhomologous ends

biological_process

During DSBR via single-strand annealing, the removal of nonhomologous sequences at the broken 3' single-strand DNA end before DNA repair synthesis can occur.

[ "PMID:10357855" ]

null

[]

[ "GO:0000735" ]

[ "part_of GO:0045002" ]

[ "part_of" ]

[ "GO:0045002" ]

[ "GO:0000735", "GO:0045002" ]

[ "GO:0000735", "part_of GO:0045002" ]

[]

null

false

true

1

GO:0000737

737

obsolete DNA catabolic process, endonucleolytic

biological_process

OBSOLETE. The chemical reactions and pathways resulting in the breakdown of DNA, involving the hydrolysis of internal 3',5'-phosphodiester bonds in one or two strands of deoxyribonucleotides.

[ "GOC:elh", "GOC:mah" ]

The reason is that these terms represent Molecular functions in the Biological Process ontology.

[ "DNA breakdown, endonucleolytic", "DNA degradation, endonucleolytic", "endonucleolytic degradation of DNA", "endonucleolytic DNA catabolism" ]

[ "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0006308" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24075\" xsd:anyURI" ]

null

true

3

GO:0000738

738

obsolete DNA catabolic process, exonucleolytic

biological_process

OBSOLETE. The chemical reactions and pathways resulting in the breakdown of DNA, involving the hydrolysis of terminal 3',5'-phosphodiester bonds in one or two strands of deoxyribonucleotides.

[ "GOC:elh", "GOC:mah" ]

The reason is that these terms represent Molecular functions in the Biological Process ontology.

[ "DNA breakdown, exonucleolytic", "DNA degradation, exonucleolytic", "exonucleolytic degradation of DNA" ]

[ "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0006308" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24075\" xsd:anyURI" ]

null

true

6

GO:0000739

739

obsolete DNA strand annealing activity

molecular_function

OBSOLETE. Facilitates the base-pairing of complementary single-stranded DNA.

[ "GOC:elh" ]

This term was made obsolete because it describes a process and not an activity.

[ "DNA strand annealing activity" ]

[ "EXACT" ]

[]

[ "GO:0036310" ]

[]

null

true

8

GO:0000740

740

nuclear membrane fusion

biological_process

The joining of 2 or more lipid bilayer membranes that surround the nucleus.

[ "GOC:elh" ]

null

[]

[ "GO:0071763", "GO:0090174" ]

[]

[ "GO:0071763", "GO:0090174" ]

[]

null

false

true

1

GO:0000741

741

karyogamy

biological_process

The creation of a single nucleus from multiple nuclei as a result of fusing the lipid bilayers that surround each nuclei.

[ "GOC:elh" ]

null

[ "nuclear fusion", "nuclear fusion during karyogamy" ]

[ "EXACT", "EXACT" ]

[ "GO:0007335" ]

[]

[ "Wikipedia:Karyogamy" ]

[ "GO:0006997", "GO:0048284" ]

[]

[ "GO:0006997", "GO:0048284" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31276\" xsd:anyURI" ]

null

false

true

5

GO:0000742

742

karyogamy involved in conjugation with cellular fusion

biological_process

During sexual reproduction, the creation of a single nucleus from multiple nuclei as a result of fusing the lipid bilayers that surround each nuclei. This occurs after cytogamy.

[ "GOC:elh" ]

null

[ "karyogamy during conjugation with cellular fusion" ]

[ "RELATED" ]

[]

[ "GO:0000741" ]

[ "part_of GO:0000747" ]

[ "part_of" ]

[ "GO:0000747" ]

[ "GO:0000741", "GO:0000747" ]

[ "GO:0000741", "part_of GO:0000747" ]

[]

null

false

true

5

GO:0000743

743

nuclear migration involved in conjugation with cellular fusion

biological_process

The microtubule-based movement of nuclei towards one another as a prelude to karyogamy in organisms undergoing conjugation with cellular fusion.

[ "GOC:clt", "GOC:vw", "PMID:16380440" ]

null

[ "nuclear congression", "nuclear migration during conjugation with cellular fusion" ]

[ "EXACT", "RELATED" ]

[ "GO:0006946" ]

[]

[ "GO:0030473" ]

[ "part_of GO:0000747" ]

[ "part_of" ]

[ "GO:0000747" ]

[ "GO:0000747", "GO:0030473" ]

[ "GO:0007097", "part_of GO:0000747" ]

[]

null

false

true

2

GO:0000744

744

obsolete karyogamy involved in conjugation with mutual genetic exchange

biological_process

OBSOLETE. During sexual reproduction, the creation of a single nucleus from two nuclei as a result of fusing the nuclear envelopes that surround each nuclei. This takes place following the mutual exchange of one of the two nuclei produced by the mitosis that follows the second meiotic nuclear division. This occurs in c...

[ "GOC:mah", "GOC:pg" ]

This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.

[ "karyogamy involved in conjugation without cellular fusion" ]

[ "EXACT" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/16248\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31306\" xsd:anyURI" ]

null

true

3

GO:0000745

745

obsolete nuclear migration involved in conjugation with mutual genetic exchange

biological_process

OBSOLETE. The net movement of nuclei towards one another, leading to the bilateral transfer of genetic material in organisms undergoing conjugation without cellular fusion.

[ "GOC:clt", "GOC:mah" ]

This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.

[ "nuclear exchange during conjugation without cellular fusion", "nuclear migration involved in conjugation without cellular fusion" ]

[ "RELATED", "EXACT" ]

[]

[ "GO:0000748", "GO:0007097" ]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31254\" xsd:anyURI" ]

null

true

9

GO:0000746

746

obsolete conjugation

biological_process

OBSOLETE. The union or introduction of genetic information from compatible mating types that results in a genetically different individual. Conjugation requires direct cellular contact between the organisms.

[ "GOC:elh" ]

This term was obsoleted because it is an unnecessary grouping class.

[]

[ "Wikipedia:Conjugation" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22916\" xsd:anyURI" ]

null

true

3

GO:0000747

747

conjugation with cellular fusion

biological_process

A conjugation process that results in the union of cellular and genetic information from compatible mating types. An example of this process is found in Saccharomyces cerevisiae.

[ "GOC:elh" ]

null

[ "cell fusion", "mating" ]

[ "RELATED", "RELATED" ]

[ "GO:0007322", "GO:0007333", "GO:0030461", "GO:0030477" ]

[ "goslim_candida", "goslim_pir", "goslim_pombe", "goslim_yeast" ]

[ "Wikipedia:Conjugation" ]

[ "GO:0019953" ]

[ "has_part GO:0140253" ]

[ "has_part" ]

[ "GO:0140253" ]

[ "GO:0019953", "GO:0140253" ]

[]

null

false

true

3

GO:0000748

748

conjugation with mutual genetic exchange

biological_process

A conjugation process that results in the mutual exchange and union of only genetic information between compatible mating types. Conjugation without cellular fusion requires direct cellular contact between the organisms without plasma membrane fusion. The organisms involved in conjugation without cellular fusion separa...

[ "GOC:elh", "PMID:22444146" ]

null

[ "conjugation without cellular fusion" ]

[ "EXACT" ]

[]

[ "GO:0019953" ]

[]

[ "GO:0019953" ]

[]

null

false

true

1

GO:0000749

749

response to pheromone triggering conjugation with cellular fusion

biological_process

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus that positively regulates the process of conjugation with cellular fusion. An example of this process is found in Saccharomyc...

[ "GOC:clt" ]

null

[ "response to pheromone during conjugation with cellular fusion" ]

[ "RELATED" ]

[ "GO:0007328", "GO:0030434" ]

[]

[ "GO:0071444" ]

[ "positively_regulates GO:0000747" ]

[ "positively_regulates" ]

[ "GO:0000747" ]

[ "GO:0000747", "GO:0071444" ]

[ "GO:0019236", "positively_regulates GO:0000747" ]

[]

null

false

true

3

GO:0000750

750

pheromone-dependent signal transduction involved in conjugation with cellular fusion

biological_process

A signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation with cellular fusion. An example of this process is found in Saccharomyces cerevisiae.

[ "GOC:clt" ]

null

[ "transduction of mating signal" ]

[ "BROAD" ]

[ "GO:0007330", "GO:0030454" ]

[]

[ "GO:0032005" ]

[ "part_of GO:0000749" ]

[ "part_of" ]

[ "GO:0000749" ]

[ "GO:0000749", "GO:0032005" ]

[]

null

false

true

6

GO:0000752

752

agglutination involved in conjugation with cellular fusion

biological_process

The aggregation or adhesion of compatible mating types via complementary cell-cell interactions during conjugation with cellular fusion of a unicellular organism. An example of this process is agglutination in Saccharomyces cerevisiae.

[ "GOC:elh" ]

null

[ "agglutination", "cell-cell adhesion during conjugation with cellular fusion", "cell-cell adhesion during mating" ]

[ "BROAD", "EXACT", "EXACT" ]

[ "GO:0007334" ]

[]

[ "GO:0051703", "GO:0140039" ]

[ "part_of GO:0000747", "part_of GO:0000749" ]

[ "part_of", "part_of" ]

[ "GO:0000747", "GO:0000749" ]

[ "GO:0000747", "GO:0000749", "GO:0051703", "GO:0140039" ]

[]

null

false

true

6

GO:0000753

753

cell morphogenesis involved in conjugation with cellular fusion

biological_process

The change in form (cell shape and size) that occurs during sexual reproduction in order to facilitate direct contact between the compatible mating types in organisms that undergo conjugation cellular fusion.

[ "GOC:clt" ]

null

[ "shmoo orientation", "shmooing" ]

[ "NARROW", "NARROW" ]

[ "GO:0007332" ]

[]

[ "GO:0000902" ]

[ "part_of GO:0000747" ]

[ "part_of" ]

[ "GO:0000747" ]

[ "GO:0000747", "GO:0000902" ]

[ "GO:0000902", "part_of GO:0000747" ]

[]

null

false

true

8

GO:0000754

754

obsolete adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion

biological_process

OBSOLETE. In organisms that undergo conjugation with cellular fusion, the process resulting in desensitization following exposure to pheromone stimulus that act to down-regulate further stimulation or block initial conjugation responses. An example of this is the adaptation to pheromone during conjugation with cellular...

[ "GOC:clt" ]

This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.

[ "adaptation of signalling pathway by response to pheromone involved in conjugation with cellular fusion", "adaptation to pheromone during conjugation with cellular fusion", "desensitization to pheromone during conjugation with cellular fusion" ]

[ "EXACT", "RELATED", "EXACT" ]

[ "GO:0007331", "GO:0030453" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31330\" xsd:anyURI" ]

null

true

4

GO:0000755

755

cytogamy

biological_process

A reproductive process in a single-celled organism in which the cytoplasm of two mating cells fuse, resulting in the formation of a single cell containing the combined cellular contents.

[ "GOC:vw" ]

Cytogamy follows cell recognition and mating projection formation (when present) and precedes or accompanies nuclear fusion (karyogamy).

[ "zygote formation" ]

[ "RELATED" ]

[ "GO:0000218", "GO:0030462" ]

[]

[ "GO:0022413", "GO:0140253" ]

[ "part_of GO:0000747" ]

[ "part_of" ]

[ "GO:0000747" ]

[ "GO:0000747", "GO:0022413", "GO:0140253" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31270\" xsd:anyURI" ]

null

false

true

4

GO:0000756

756

response to pheromone regulating conjugation with mutual genetic exchange

biological_process

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus regulating the process of conjugation without cellular fusion.

[ "GOC:clt" ]

null

[ "response to pheromone triggering conjugation without cellular fusion" ]

[ "EXACT" ]

[]

[ "GO:0007154", "GO:0071444" ]

[ "regulates GO:0000748" ]

[ "regulates" ]

[ "GO:0000748" ]

[ "GO:0000748", "GO:0007154", "GO:0071444" ]

[ "GO:0019236", "regulates GO:0000748" ]

[]

null

false

true

8

GO:0000757

757

obsolete signal transduction involved in regulation of conjugation with mutual genetic exchange

biological_process

OBSOLETE. A signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation without cellular fusion.

[ "GOC:clt" ]

This term was obsoleted because its label and definitions were not clear. It had never been used for annotation.

[ "signal transduction involved in conjugation without cellular fusion" ]

[ "EXACT" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/15815\" xsd:anyURI" ]

null

true

9

GO:0000758

758

obsolete agglutination involved in conjugation with mutual genetic exchange

biological_process

OBSOLETE. The aggregation or adhesion of compatible mating types via complementary cell-cell interactions during conjugation without cellular fusion of a unicellular organism.

[ "GOC:elh" ]

This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.

[ "agglutination involved in conjugation without cellular fusion", "sexual flocculation" ]

[ "EXACT", "EXACT" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31306\" xsd:anyURI" ]

null

true

4

GO:0000759

759

obsolete cell morphogenesis involved in conjugation with mutual genetic exchange

biological_process

OBSOLETE. The change in form (cell shape and size) that occurs during sexual reproduction in order to facilitate direct contact between the compatible mating types in organisms that undergo conjugation without cellular fusion.

[ "GOC:clt" ]

This term was obsoleted because there is no evidence that this process exists.

[ "cellular morphogenesis involved in conjugation without cellular fusion" ]

[ "EXACT" ]

[]

null

true

4

GO:0000760

760

adaptation to pheromone regulating conjugation with mutual genetic exchange

biological_process

In organisms that undergo conjugation without cellular fusion, the process resulting in desensitization following exposure to pheromone stimulus that act to down-regulate further stimulation or block initial conjugation responses.

[ "GOC:clt" ]

null

[ "adaptation to pheromone involved conjugation without cellular fusion", "desensitization to pheromone during conjugation without cellular fusion" ]

[ "RELATED", "EXACT" ]

[]

[ "GO:0000756", "GO:0022401", "GO:2000241" ]

[]

[ "GO:0000756", "GO:0022401", "GO:2000241" ]

[]

null

false

true

7

GO:0000761

761

conjugant formation

biological_process

During conjugation without cellular fusion, the process that results in pairing complementary mating types. Localized morphological, cytological, and cytoskeletal changes connect the mating types without cytoplasmic mixing.

[ "GOC:elh" ]

null

[]

[ "GO:0098610" ]

[ "part_of GO:0000748" ]

[ "part_of" ]

[ "GO:0000748" ]

[ "GO:0000748", "GO:0098610" ]

[]

null

false

true

2

GO:0000762

762

pheromone-induced unidirectional conjugation

biological_process

Unidirectional transfer of genetic information triggered by to a pheromone signal.

[ "GOC:elh", "PMID:17360276", "PMID:27021562", "PMID:31191478" ]

null

[]

[ "GO:0009291" ]

[]

[ "GO:0009291" ]

[]

null

false

true

7

GO:0000763

763

obsolete cell morphogenesis involved in unidirectional conjugation

biological_process

OBSOLETE. The change in form (cell shape and size) that occurs during sexual reproduction in order to facilitate direct contact between the compatible mating types in organisms that undergo unidirectional conjugation.

[ "GOC:clt" ]

This term was made obsolete because unidirectional conjugation occurs only in prokaryotes, which do not undergo morphogenetic changes associated with conjugation. In short, the process described by this term does not occur.

[ "cell morphogenesis involved in unidirectional conjugation" ]

[ "EXACT" ]

[]

null

true

3

GO:0000764

764

obsolete cellular morphogenesis involved in pheromone-induced unidirectional conjugation

biological_process

OBSOLETE. The change in form (cell shape and size) that contributes to sexual reproduction in order to facilitate direct contact between the compatible mating types in organisms that undergo pheromone-induced unidirectional conjugation.

[ "GOC:clt" ]

This term was made obsolete because unidirectional conjugation occurs only in prokaryotes, which do not undergo morphogenetic changes associated with conjugation. In short, the process described by this term does not occur.

[ "cellular morphogenesis during pheromone-induced unidirectional", "cellular morphogenesis involved in pheromone-induced unidirectional conjugation" ]

[ "RELATED", "EXACT" ]

[]

null

true

9

GO:0000765

765

response to pheromone regulating pheromone-induced unidirectional conjugation

biological_process

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus that regulates the process of pheromone-induced unidirectional conjugation.

[ "GOC:clt" ]

null

[ "response to pheromone during pheromone-induced unidirectional" ]

[ "RELATED" ]

[]

[ "GO:0019236" ]

[ "regulates GO:0000762" ]

[ "regulates" ]

[ "GO:0000762" ]

[ "GO:0000762", "GO:0019236" ]

[ "GO:0019236", "regulates GO:0000762" ]

[]

null

false

true

8

GO:0000767

767

obsolete cell morphogenesis involved in conjugation

biological_process

OBSOLETE. The change in form (cell shape and size) that occurs during sexual reproduction in order to facilitate direct contact between the compatible mating types.

[ "GOC:elh" ]

This term was obsoleted because it is an unnecessary grouping class.

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22916\" xsd:anyURI" ]

null

true

2

GO:0000768

768

syncytium formation by cell-cell fusion

biological_process

The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.

[ "GOC:mtg_muscle", "GOC:tb" ]

null

[ "syncytium formation by plasma membrane fusion" ]

[ "EXACT" ]

[]

[ "GO:0140253" ]

[]

[ "GO:0140253" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31270\" xsd:anyURI" ]

null

false

true

3

GO:0000769

769

syncytium formation by mitosis without cytokinesis

biological_process

The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by one or more rounds of nuclear division without cytokinesis.

[ "GOC:mah", "GOC:tb" ]

null

[ "syncytium formation by mitosis without cell division" ]

[ "RELATED" ]

[]

[ "GO:0033301" ]

[]

[ "GO:0033301" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31270\" xsd:anyURI" ]

null

false

true

7

GO:0000770

770

peptide pheromone export

biological_process

The directed movement of a peptide pheromone out of a cell by a secretion or export pathway used solely for the export of peptide pheromones.

[ "GOC:elh" ]

null

[ "a-factor export" ]

[ "NARROW" ]

[ "GO:0007325" ]

[]

[ "GO:0071705" ]

[]

[ "GO:0071705" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23245\" xsd:anyURI" ]

null

false

true

4

GO:0000771

771

obsolete agglutination involved in conjugation

biological_process

OBSOLETE. The aggregation or adhesion of compatible mating types via complementary cell-cell interactions prior to the formation of irreversible cellular contacts during conjugation.

[ "GOC:elh" ]

This term was obsoleted because it is an unnecessary grouping class.

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22916\" xsd:anyURI" ]

null

true

5

GO:0000772

772

mating pheromone activity

molecular_function

The activity of binding to and activating specific cell surface receptors, thereby inducing a behavioral or physiological response(s) from a responding organism or cell that leads to the transfer or union of genetic material between organisms or cells. The mating pheromone can either be retained on the cell surface or ...

[ "GOC:clt", "GOC:elh" ]

null

[]

[ "GO:0005186" ]

[]

[ "GO:0005186" ]

[]

null

false

true

1

GO:0000773

773

phosphatidyl-N-methylethanolamine N-methyltransferase activity

molecular_function

Catalysis of the reaction: S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine = S-adenosyl-L-homocysteine + phosphatidyl-N-dimethylethanolamine. Also catalyzes the transfer of a further methylgroup, producing phosphatidylcholine.

[ "EC:2.1.1.71", "PMID:19366698" ]

null

[ "methyltransferase II", "phosphatidyl-N-methylethanolamine methyltransferase activity", "phosphatidyl-N-monomethylethanolamine methyltransferase activity", "phosphatidylethanolamine methyltransferase I", "phosphatidylmonomethylethanolamine methyltransferase activity", "phospholipid methyltransferase activ...

[ "RELATED", "RELATED", "RELATED", "RELATED", "RELATED", "RELATED", "EXACT", "RELATED" ]

[]

[ "EC:2.1.1.71", "KEGG_REACTION:R01320", "KEGG_REACTION:R03424", "MetaCyc:2.1.1.71-RXN", "MetaCyc:RXN4FS-2", "RHEA:32735", "RHEA:32739" ]

[ "GO:0008170", "GO:0008757" ]

[]

[ "GO:0008170", "GO:0008757" ]

[]

[ "skos:exactMatch EC:2.1.1.71", "skos:exactMatch MetaCyc:2.1.1.71-RXN", "skos:narrowMatch KEGG_REACTION:R01320", "skos:narrowMatch KEGG_REACTION:R03424", "skos:narrowMatch MetaCyc:RXN4FS-2", "skos:narrowMatch RHEA:32735", "skos:narrowMatch RHEA:32739", "term_tracker_item \"https://github.com/geneontolo...

null

false

true

5

GO:0000774

774

adenyl-nucleotide exchange factor activity

molecular_function

Binds to and stimulates the hydrolysis and exchange of adenyl nucleotides by other proteins.

[ "GOC:kd" ]

null

[]

[ "Reactome:R-HSA-5252079 \"HSP110s exchange ATP for ADP on HSP70s:ADP\"" ]

[ "GO:0060590" ]

[ "negatively_regulates GO:0043531", "positively_regulates GO:0005524" ]

[ "negatively_regulates", "positively_regulates" ]

[ "GO:0043531", "GO:0005524" ]

[ "GO:0005524", "GO:0043531", "GO:0060590" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27684\" xsd:anyURI" ]

null

false

true

3

GO:0000775

775

chromosome, centromeric region

cellular_component

The region of a chromosome that includes the centromeric DNA and associated proteins. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.

[ "GOC:cjm", "GOC:elh", "GOC:kmv", "GOC:pr" ]

Note that this term can be used in place of the obsolete cellular component term 'centromere ; GO:0005698'.

[ "centromere", "centromere complex", "chromosome, centric region", "chromosome, pericentric region" ]

[ "RELATED", "EXACT", "EXACT", "RELATED" ]

[ "GO:0097521" ]

[]

[ "SO:0000577" ]

[ "GO:0098687" ]

[]

[ "GO:0098687" ]

[]

null

false

true

8

GO:0000776

776

kinetochore

cellular_component

A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.

[ "GOC:elh" ]

Note that the kinetochore overlaps the centromeric DNA, but centromeric DNA is not part of the kinetochore.

[ "condensed chromosome kinetochore", "condensed nuclear chromosome kinetochore", "NMS complex" ]

[ "EXACT", "EXACT", "NARROW" ]

[ "GO:0000777", "GO:0000778", "GO:0005699", "GO:0031617" ]

[ "goslim_pir" ]

[ "Wikipedia:Kinetochore" ]

[ "GO:0043232", "GO:0099080" ]

[ "part_of GO:0000779" ]

[ "part_of" ]

[ "GO:0000779" ]

[ "GO:0000779", "GO:0043232", "GO:0099080" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21126\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23605\" xsd:anyURI" ]

null

false

true

4

GO:0000779

779

condensed chromosome, centromeric region

cellular_component

The region of a condensed chromosome that includes the centromere and associated proteins, including the kinetochore. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.

[ "GOC:elh", "GOC:kmv" ]

Note that this term can be used in place of the obsolete cellular component term 'centromere ; GO:0005698'. Use with caution because this term refers to a specific region of the chromosome and not a protein complex.

[ "condensed chromosome, centric region", "condensed chromosome, centromere", "condensed chromosome, pericentric region", "condensed nuclear chromosome, centromeric region" ]

[ "EXACT", "RELATED", "RELATED", "NARROW" ]

[ "GO:0000780" ]

[]

[ "GO:0000775" ]

[ "part_of GO:0000793" ]

[ "part_of" ]

[ "GO:0000793" ]

[ "GO:0000775", "GO:0000793" ]

[ "GO:0000775", "part_of GO:0000793" ]

[]

null

false

true

9

GO:0000781

781

chromosome, telomeric region

cellular_component

The end of a linear chromosome, required for the integrity and maintenance of the end. A chromosome telomere usually includes a region of telomerase-encoded repeats the length of which rarely exceeds 20 bp each and that permits the formation of a telomeric loop (T-loop). The telomeric repeat region is usually preceded ...

[ "GOC:elh" ]

Note that this term can be used in place of the obsolete cellular component term 'telomere ; GO:0005696'. Use with caution because this term refers to a specific region of the chromosome and not a protein complex.

[ "nuclear chromosome, telomere", "nuclear chromosome, telomeric region", "telomere" ]

[ "NARROW", "NARROW", "RELATED" ]

[ "GO:0000784" ]

[]

[ "SO:0000624" ]

[ "GO:0098687" ]

[]

[ "GO:0098687" ]

[]

null

false

true

9

GO:0000783

783

nuclear telomere cap complex

cellular_component

A complex of DNA and protein located at the end of a linear chromosome in the nucleus that protects and stabilizes a linear chromosome.

[ "GOC:elh" ]

Note that this term can be used in place of the obsolete cellular component term 'telomere ; GO:0005696'. Use with caution because this term refers to a specific protein complex and not a region of the chromosome.

[]

[ "GO:0000782", "GO:0140513" ]

[]

[ "GO:0000782", "GO:0140513" ]

[]

null

false

true

6

GO:0000785

785

chromatin

cellular_component

The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome.

[ "GOC:elh", "PMID:20404130" ]

Chromosomes include parts that are not part of the chromatin. Examples include the kinetochore.

[ "chromosome scaffold", "cytoplasmic chromatin", "nuclear chromatin" ]

[ "RELATED", "NARROW", "NARROW" ]

[ "GO:0000789", "GO:0000790", "GO:0005717" ]

[]

[ "NIF_Subcellular:sao1615953555" ]

[ "GO:0110165" ]

[ "part_of GO:0005694" ]

[ "part_of" ]

[ "GO:0005694" ]

[ "GO:0005694", "GO:0110165" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28301\" xsd:anyURI" ]

null

false

true

6

GO:0000786

786

nucleosome

cellular_component

A complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA into higher order structures.

[ "GOC:elh" ]

null

[ "cytoplasmic nucleosome", "nuclear nucleosome" ]

[ "NARROW", "NARROW" ]

[ "GO:0000787", "GO:0000788", "GO:0005718" ]

[ "goslim_pir" ]

[ "Wikipedia:Nucleosome" ]

[ "GO:0032993" ]

[ "part_of GO:0000785" ]

[ "part_of" ]

[ "GO:0000785" ]

[ "GO:0000785", "GO:0032993" ]

[]

null

false

true

3

GO:0000791

791

euchromatin

cellular_component

A dispersed and relatively uncompacted form of chromatin that is in a transcription-competent conformation.

[ "PMID:32017156" ]

null

[ "nuclear euchromatin", "transcriptionally active chromatin" ]

[ "RELATED", "EXACT" ]

[ "GO:0005719", "GO:0035327" ]

[]

[ "NIF_Subcellular:sao445485807", "Wikipedia:Euchromatin" ]

[ "GO:0000785" ]

[]

[ "GO:0000785" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22355\" xsd:anyURI" ]

null

false

true

5

GO:0000792

792

heterochromatin

cellular_component

A compact and highly condensed form of chromatin that is refractory to transcription.

[ "PMID:32017156" ]

null

[ "nuclear heterochromatin", "transcriptionally inactive chromatin", "transcriptionally silent chromatin" ]

[ "NARROW", "EXACT", "EXACT" ]

[ "GO:0005720", "GO:0035328" ]

[]

[ "NIF_Subcellular:sao581845896", "Wikipedia:Heterochromatin" ]

[ "GO:0000785" ]

[]

[ "GO:0000785" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22355\" xsd:anyURI" ]

null

false

true

6

GO:0000793

793

condensed chromosome

cellular_component

A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct structure.

[ "GOC:elh" ]

Note that this term can be used to annotate gene products that localize to a mitotic chromosome in an organism that undergoes an 'open mitosis' in which the nuclear envelope breaks down during mitosis.

[ "cytoplasmic mitotic chromosome", "metaphase chromosome", "mitotic chromosome" ]

[ "RELATED", "RELATED", "RELATED" ]

[]

[ "GO:0005694" ]

[]

[ "GO:0005694" ]

[]

null

false

true

6

GO:0000794

794

condensed nuclear chromosome

cellular_component

A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct nuclear chromosome.

[ "GOC:elh" ]

Note that this term and its children can be used to annotate gene products that localize to a mitotic chromosome in an organism that undergoes a 'closed mitosis' in which the nuclear envelope does not break down during mitosis and for gene products that localize to a meiotic chromosome.

[ "meiotic chromosome", "nuclear mitotic chromosome" ]

[ "RELATED", "RELATED" ]

[]

[ "GO:0000228", "GO:0000793" ]

[]

[ "GO:0000228", "GO:0000793" ]

[ "GO:0000793", "part_of GO:0005634" ]

[]

null

false

true

5

GO:0000795

795

synaptonemal complex

cellular_component

A proteinaceous scaffold found between homologous chromosomes during meiosis. It consists of 2 lateral elements and a central element, all running parallel to each other. Transverse filaments connect the lateral elements to the central element.

[ "DOI:10.5772/29752", "GOC:elh" ]

null

[]

[ "GO:0005716" ]

[]

[ "Wikipedia:Synaptonemal_complex" ]

[ "GO:0099086" ]

[]

[ "GO:0099086" ]

[]

null

false

true

4

GO:0000796

796

condensin complex

cellular_component

A multisubunit protein complex that plays a central role in chromosome condensation in meiosis and mitosis.

[ "GOC:elh", "PMID:17268547", "PMID:21795393" ]

null

[ "13S condensin complex", "8S condensin complex", "condensin core heterodimer", "condensin I complex", "nuclear condensin complex", "SMC complex", "Smc2-Smc4 complex" ]

[ "NARROW", "NARROW", "NARROW", "NARROW", "NARROW", "RELATED", "NARROW" ]

[ "GO:0000797", "GO:0000799", "GO:0005676", "GO:0008620", "GO:0008621", "GO:0061814" ]

[ "goslim_pir" ]

[]

[ "GO:0032991" ]

[ "part_of GO:0005694" ]

[ "part_of" ]

[ "GO:0005694" ]

[ "GO:0005694", "GO:0032991" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/12832\" xsd:anyURI" ]

null

false

true

2

GO:0000800

800

lateral element

cellular_component

A proteinaceous core found between sister chromatids during meiotic prophase.

[ "GOC:elh" ]

In species that have a synaptonemal complex, the lateral elements are part of this complex. S.pombe is an example of a species that lacks a (canonical) synaptonemal complex, but still has lateral elements.

[ "axial element" ]

[ "EXACT" ]

[]

[ "GO:0110165" ]

[ "part_of GO:0000795" ]

[ "part_of" ]

[ "GO:0000795" ]

[ "GO:0000795", "GO:0110165" ]

[]

null

false

true

7

GO:0000801

801

central element

cellular_component

A structural unit of the synaptonemal complex found between the lateral elements.

[ "GOC:elh" ]

null

[]

[ "GO:0110165" ]

[ "part_of GO:0000795" ]

[ "part_of" ]

[ "GO:0000795" ]

[ "GO:0000795", "GO:0110165" ]

[]

null

false

true

6

GO:0000802

802

transverse filament

cellular_component

A structural unit of the synaptonemal complex that spans the regions between the lateral elements and connects them.

[ "GOC:elh" ]

null

[]

[ "GO:0110165" ]

[ "part_of GO:0000795" ]

[ "part_of" ]

[ "GO:0000795" ]

[ "GO:0000795", "GO:0110165" ]

[]

null

false

true

8

GO:0000803

803

sex chromosome

cellular_component

A chromosome involved in sex determination.

[ "GOC:elh" ]

null

[]

[ "GO:0005694" ]

[]

[ "GO:0005694" ]

[]

null

false

true

2

GO:0000804

804

W chromosome

cellular_component

The sex chromosome present in females of species in which the female is the heterogametic sex; generally, the sex chromosome that pairs with the Z chromosome in the heterogametic sex. The W chromosome is absent from the cells of males and present in one copy in the somatic cells of females.

[ "GOC:mah", "GOC:mr", "ISBN:0321000382", "PMID:20622855" ]

null

[]

[ "Wikipedia:ZW_sex-determination_system" ]

[ "GO:0000803" ]

[]

[ "GO:0000803" ]

[]

null

false

true

7

GO:0000805

805

X chromosome

cellular_component

The sex chromosome present in both sexes of species in which the male is the heterogametic sex. Two copies of the X chromosome are present in each somatic cell of females and one copy is present in males.

[ "GOC:mah", "GOC:mr", "ISBN:0582227089", "PMID:20622855", "Wikipedia:XY_sex-determination_system" ]

null

[]

[ "Wikipedia:X_chromosome" ]

[ "GO:0000803" ]

[]

[ "GO:0000803" ]

[]

null

false

true

3

GO:0000806

806

Y chromosome

cellular_component

The sex chromosome present in males of species in which the male is the heterogametic sex; generally, the sex chromosome that pairs with the X chromosome in the heterogametic sex. The Y chromosome is absent from the cells of females and present in one copy in the somatic cells of males.

[ "GOC:mah", "GOC:mr", "ISBN:0582227089", "PMID:20622855", "Wikipedia:XY_sex-determination_system" ]

null

[]

[ "Wikipedia:Y_chromosome" ]

[ "GO:0000803" ]

[]

[ "GO:0000803" ]

[]

null

false

true

6

GO:0000807

807

Z chromosome

cellular_component

The sex chromosome present in both sexes of species in which the female is the heterogametic sex. Two copies of the Z chromosome are present in each somatic cell of males and one copy is present in females.

[ "GOC:mah", "GOC:mr", "ISBN:0321000382", "PMID:20622855" ]

null

[]

[ "Wikipedia:ZW_sex-determination_system" ]

[ "GO:0000803" ]

[]

[ "GO:0000803" ]

[]

null

false

true

2

GO:0000809

809

cytoplasmic origin of replication recognition complex

cellular_component

A multisubunit complex that is located at the replication origins of a chromosome in the cytoplasm.

[ "GOC:elh" ]

null

[ "cytoplasmic ORC", "prokaryotic ORC" ]

[ "EXACT", "RELATED" ]

[]

[ "GO:0000808" ]

[ "part_of GO:0005737" ]

[ "part_of" ]

[ "GO:0005737" ]

[ "GO:0000808", "GO:0005737" ]

[ "GO:0000808", "part_of GO:0005737" ]

[]

null

false

true

7

GO:0000810

810

diacylglycerol diphosphate phosphatase activity

molecular_function

Catalysis of the reaction: a 1,2-diacyl-sn-glycerol 3-diphosphate + H2O = a 1,2-diacyl-sn-glycerol 3-phosphate + phosphate.

[ "GOC:kad", "PMID:8567632", "PMID:9452443", "RHEA:27449" ]

null

[ "DGPP phosphatase activity", "DGPP phosphohydrolase activity", "diacylglycerol pyrophosphate phosphatase activity" ]

[ "EXACT", "EXACT", "EXACT" ]

[]

[ "EC:3.6.1.75", "MetaCyc:RXN-11277", "RHEA:27449", "RHEA:42856", "RHEA:62092" ]

[ "GO:0016462" ]

[]

[ "GO:0016462" ]

[]

[ "skos:exactMatch EC:3.6.1.75", "skos:exactMatch RHEA:27449", "skos:narrowMatch RHEA:42856", "skos:narrowMatch RHEA:62092", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24052\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI...

null

false

true

5

GO:0000811

811

GINS complex

cellular_component

A heterotetrameric protein complex that associates with replication origins, where it is required for the initiation of DNA replication, and with replication forks.

[ "GOC:rb", "GOC:rn", "PMID:12730134", "PMID:16990792", "PMID:17467990" ]

null

[ "Go, Ichi, Ni and San complex" ]

[ "EXACT" ]

[]

[ "GO:0031261" ]

[ "part_of GO:0000228" ]

[ "part_of" ]

[ "GO:0000228" ]

[ "GO:0000228", "GO:0031261" ]

[]

null

false

true

7

GO:0000812

812

Swr1 complex

cellular_component

A multisubunit protein complex that is involved in chromatin remodeling. It is required for the incorporation of the histone variant H2AZ into chromatin. In S. cerevisiae, the complex contains Swr1p, a Swi2/Snf2-related ATPase, and 12 additional subunits.

[ "GOC:rb", "PMID:14645854", "PMID:14690608", "PMID:19355820" ]

null

[ "SWR-C" ]

[ "EXACT" ]

[]

[ "GO:0000118", "GO:0097346" ]

[ "part_of GO:0000228" ]

[ "part_of" ]

[ "GO:0000228" ]

[ "GO:0000118", "GO:0000228", "GO:0097346" ]

[]

null

false

true

7

GO:0000813

813

ESCRT I complex

cellular_component

An endosomal sorting complex required for transport. It consists of the class E vacuolar protein sorting (Vps) proteins and interacts with ubiquitinated cargoes.

[ "GOC:rb", "PMID:12892785", "PMID:12900393" ]

null

[ "endosomal sorting complex required for transport" ]

[ "BROAD" ]

[]

[ "GO:0036452", "GO:0098796" ]

[ "part_of GO:0010008" ]

[ "part_of" ]

[ "GO:0010008" ]

[ "GO:0010008", "GO:0036452", "GO:0098796" ]

[]

null

false

true

4

GO:0000814

814

ESCRT II complex

cellular_component

An endosomal sorting complex required for transport and functions downstream of ESCRT I complex. It consists of the class E vacuolar protein sorting (Vps) proteins and is required for the membrane recruitment of ESCRT III complex and binds to ubiquitinated cargoes.

[ "GOC:rb", "PMID:12892785", "PMID:12900393" ]

null

[ "endosomal sorting complex required for transport" ]

[ "BROAD" ]

[]

[ "GO:0036452", "GO:0098796" ]

[ "part_of GO:0010008" ]

[ "part_of" ]

[ "GO:0010008" ]

[ "GO:0010008", "GO:0036452", "GO:0098796" ]

[]

null

false

true

8

GO:0000815

815

ESCRT III complex

cellular_component

A complex with membrane scission activity that plays a major role in many processes where membranes are remodelled - including endosomal transport (vesicle budding), nuclear envelope organisation (membrane closure, mitotic bridge cleavage), and cytokinesis (abscission).

[ "PMID:17556548", "PMID:22361144", "PMID:28242692", "PMID:31132588", "PMID:32243490", "PMID:34449766" ]

null

[ "endosomal sorting complex required for transport" ]

[ "BROAD" ]

[]

[ "GO:0036452", "GO:0098796" ]

[ "part_of GO:0010008" ]

[ "part_of" ]

[ "GO:0010008" ]

[ "GO:0010008", "GO:0036452", "GO:0098796" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22085\" xsd:anyURI" ]

null

false

true

4

GO:0000817

817

COMA complex

cellular_component

A kinetochore multiprotein complex that bridges the subunits that are in contact with centromeric DNA and the subunits bound to microtubules during kinetochore assembly. In yeast, consists of Ctf19p, Okp1p, Mcm21p, and Ame1p.

[ "GOC:se", "PMID:14633972" ]

null

[ "Ctf19p-Okp1p-Mcm1p-Ame1p complex" ]

[ "EXACT" ]

[]

[ "GO:0140513" ]

[ "part_of GO:0000228", "part_of GO:0000776" ]

[ "part_of", "part_of" ]

[ "GO:0000228", "GO:0000776" ]

[ "GO:0000228", "GO:0000776", "GO:0140513" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21126\" xsd:anyURI" ]

null

false

true

4

GO:0000819

819

sister chromatid segregation

biological_process

The cell cycle process in which sister chromatids are organized and then physically separated and apportioned to two or more sets.

[ "GOC:ai", "GOC:elh" ]

null

[]

[ "GO:0051276", "GO:0098813" ]

[]

[ "GO:0051276", "GO:0098813" ]

[]

null

false

true

5

GO:0000820

820

obsolete regulation of glutamine family amino acid metabolic process

biological_process

OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline.

[ "GOC:curators" ]

The reason for obsoletion is that this is an unnecessary grouping term.

[ "regulation of glutamine family amino acid metabolism" ]

[ "EXACT" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29444\" xsd:anyURI" ]

null

true

7