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GO

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go_id
string
go_numeric_id
int64
name
string
namespace
string
definition
string
definition_xrefs
list
comment
string
synonyms
list
synonym_scopes
list
alt_ids
list
subsets
list
xrefs
list
is_a_ids
list
relationship_edges
list
relationship_types
list
relationship_target_ids
list
parent_ids
list
intersection_of
list
union_of
list
disjoint_from
list
replaced_by
list
consider
list
property_values
list
created_by
string
creation_date
string
is_obsolete
bool
in_go_basic
bool
split_bucket
int64
GO:0120287
120,287
obsolete regulation of aspartic endopeptidase activity, intramembrane cleaving
biological_process
OBSOLETE. Any process that modulates the frequency, rate or extent of intramembrane cleaving aspartic-type endopeptidase activity.
[ "GOC:krc", "PMID:32616437" ]
This term was obsoleted because it represents a molecular function.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20341\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22455\" xsd:anyURI" ]
krc
2020-11-19T22:06:06Z
true
true
2
GO:0120288
120,288
obsolete negative regulation of aspartic endopeptidase activity, intramembrane cleaving
biological_process
OBSOLETE. Any process that decreases the frequency, rate or extent of intramembrane cleaving aspartic-type endopeptidase activity.
[ "GOC:krc", "PMID:32616437" ]
This term was obsoleted because it represents a molecular function.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20341\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22455\" xsd:anyURI" ]
krc
2020-11-19T22:23:52Z
true
true
3
GO:0120289
120,289
obsolete positive regulation of aspartic endopeptidase activity, intramembrane cleaving
biological_process
OBSOLETE. Any process that increases the frequency, rate or extent of intramembrane cleaving aspartic-type endopeptidase activity.
[ "GOC:krc", "PMID:32616437" ]
This term was obsoleted because it represents a molecular function.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20341\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22455\" xsd:anyURI" ]
krc
2020-11-19T22:27:57Z
true
true
9
GO:0120290
120,290
stalled replication fork localization to nuclear periphery
biological_process
A cellular localization process where a DNA replication fork that has stalled is signaled to relocate and anchor to the nuclear periphery for the time necessary to complete recombination-dependent replication.
[ "GOC:krc", "GOC:mah", "PMID:33159083" ]
null
[ "stalled replication fork localization to nuclear periphery involved in replication fork processing" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0051641" ]
[ "part_of GO:0031297" ]
[ "part_of" ]
[ "GO:0031297" ]
[ "GO:0031297", "GO:0051641" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20443\" xsd:anyURI" ]
krc
2020-11-23T20:25:43Z
false
true
4
GO:0120291
120,291
negative regulation of mitotic recombination-dependent replication fork processing
biological_process
Any process that inhibits or decreases the rate of mitotic recombination-dependent replication fork processing. Suppression of recombination at replication forks is necessary to prevent template switching.
[ "GOC:krc", "GOC:mah", "PMID:28586299", "PMID:30667359", "PMID:31149897" ]
null
[ "maintenance of template fidelity during replication fork processing", "negative regulation of mitotic recombination involved in replication fork processing", "negative regulation of template switch recombination involved in replication fork processing", "suppression of template switching during replication f...
[ "EXACT", "RELATED", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0010948", "GO:0051053", "GO:1903221" ]
[ "negatively_regulates GO:1990426" ]
[ "negatively_regulates" ]
[ "GO:1990426" ]
[ "GO:0010948", "GO:0051053", "GO:1903221", "GO:1990426" ]
[ "GO:0065007", "negatively_regulates GO:1990426" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22928\" xsd:anyURI" ]
krc
2021-01-06T01:21:55Z
false
true
8
GO:0120292
120,292
positive regulation of mitotic recombination-dependent replication fork processing
biological_process
Any process that activates or increases the frequency, rate or extent of mitotic recombination-dependent replication fork processing. Regulation of mitotic recombination prevents recombination between inappropriate homologous sequences. Proteins involved in homologous recombination are required for replication restart.
[ "GOC:krc", "GOC:mah", "PMID:23093942", "PMID:28586299", "PMID:31149897" ]
null
[ "positive regulation of homologous recombination dependent replication fork recovery", "positive regulation of mitotic recombination involved in replication fork processing", "positive regulation of recombination-dependent DNA replication" ]
[ "RELATED", "RELATED", "EXACT" ]
[]
[]
[]
[ "GO:0051054", "GO:0090068", "GO:1903221" ]
[ "positively_regulates GO:1990426" ]
[ "positively_regulates" ]
[ "GO:1990426" ]
[ "GO:0051054", "GO:0090068", "GO:1903221", "GO:1990426" ]
[ "GO:0065007", "positively_regulates GO:1990426" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22928\" xsd:anyURI" ]
krc
2021-01-06T19:09:21Z
false
true
5
GO:0120293
120,293
dynein axonemal particle
cellular_component
An aggregation of axonemal dyneins, their specific assembly factors, and broadly-acting chaperones that is located in the cytoplasm.
[ "GOC:krc", "PMID:30561330", "PMID:32898505", "PMID:33263282" ]
null
[ "DynAP" ]
[ "RELATED" ]
[]
[]
[]
[ "GO:0043232" ]
[ "part_of GO:0005737" ]
[ "part_of" ]
[ "GO:0005737" ]
[ "GO:0005737", "GO:0043232" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20687\" xsd:anyURI" ]
krc
2021-01-19T01:47:17Z
false
true
5
GO:0120294
120,294
peptide serotonyltransferase activity
molecular_function
Catalysis of the reaction: L-glutaminyl-[protein] + serotonin = 5-serotonyl-L-glutamyl-[protein] + NH4+.
[ "GOC:sp", "PMID:14697203" ]
null
[]
[]
[]
[]
[ "RHEA:66552" ]
[ "GO:0016410" ]
[]
[]
[]
[ "GO:0016410" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:66552", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20685\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
krc
2021-01-19T02:07:56Z
false
true
3
GO:0120295
120,295
histone serotonyltransferase activity
molecular_function
Catalysis of the reaction: L-glutaminyl-[histone] + serotonin = 5-serotonyl-L-glutamyl-[histone] + NH4+.
[ "GOC:sp", "PMID:30867594" ]
null
[]
[]
[]
[]
[]
[ "GO:0120294", "GO:0140993" ]
[]
[]
[]
[ "GO:0120294", "GO:0140993" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch RHEA:66552", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20685\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI" ]
krc
2021-01-19T02:13:19Z
false
true
1
GO:0120296
120,296
peptide dopaminyltransferase activity
molecular_function
Catalysis of the reaction: dopamine + L-glutaminyl-[protein] = 5-dopaminyl-L-glutamyl-[protein] + NH4+.
[ "GOC:sp", "PMID:22858378", "PMID:32273471" ]
null
[]
[]
[]
[]
[ "RHEA:66556" ]
[ "GO:0016410" ]
[]
[]
[]
[ "GO:0016410" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:66556", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20685\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
krc
2021-01-19T02:20:30Z
false
true
1
GO:0120297
120,297
histone dopaminyltransferase activity
molecular_function
Catalysis of the reaction: dopamine + L-glutaminyl-[histone] = 5-dopaminyl-L-glutamyl-[histone] + NH4+.
[ "GOC:sp", "PMID:32273471" ]
null
[]
[]
[]
[]
[]
[ "GO:0120296", "GO:0140993" ]
[]
[]
[]
[ "GO:0120296", "GO:0140993" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch RHEA:66556", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20685\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI" ]
krc
2021-01-19T03:17:13Z
false
true
6
GO:0120298
120,298
peptide noradrenalinyltransferase activity
molecular_function
Catalysis of the reaction: (R)-noradrenaline + L-glutaminyl-[protein] = 5-(R)-noradrenalinyl-L-glutamyl-[protein] + NH4+.
[ "GOC:sp", "PMID:22858378" ]
null
[]
[]
[]
[]
[ "RHEA:66560" ]
[ "GO:0016410" ]
[]
[]
[]
[ "GO:0016410" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:66560", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20685\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
krc
2021-01-19T03:20:26Z
false
true
6
GO:0120299
120,299
peptide histaminyltransferase activity
molecular_function
Catalysis of the reaction: histamine + L-glutaminyl-[protein] = 5-histaminyl-L-glutamyl-[protein].
[ "GOC:sp", "PMID:23022564", "PMID:23797785" ]
null
[]
[]
[]
[]
[ "RHEA:66564" ]
[ "GO:0016410" ]
[]
[]
[]
[ "GO:0016410" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:66564", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20685\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
krc
2021-01-19T03:23:48Z
false
true
9
GO:0120301
120,301
histone lactyltransferase (CoA-dependent) activity
molecular_function
Catalysis of the reaction: (L-lysyl-[histone] + lactoyl-CoA = CoA + H+ + N(6)-lactoyl-L-lysyl-[histone].
[ "GOC:sp", "PMID:31645732" ]
null
[ "histone lactyltransferase (CoA dependent) activity", "histone lactyltransferase activity", "histone lactyltransferase activity (CoA dependent)" ]
[ "EXACT", "BROAD", "EXACT" ]
[]
[]
[]
[ "GO:0120300", "GO:0140993" ]
[]
[]
[]
[ "GO:0120300", "GO:0140993" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch RHEA:61996", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20685\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28015\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI" ]
krc
2021-01-19T03:38:56Z
false
true
9
GO:0120302
120,302
background adaptation
biological_process
Any process in which an organism changes its pigmentation (lightening in response to a brighter environment or darkening in response to a dimmer environment) in response to a change in light intensity.
[ "GOC:cvs", "GOC:krc", "PMID:10493760", "PMID:29239123", "PMID:32898924" ]
null
[]
[]
[]
[]
[]
[ "GO:0009642", "GO:0120305" ]
[]
[]
[]
[ "GO:0009642", "GO:0120305" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20524\" xsd:anyURI" ]
krc
2021-02-09T18:11:11Z
false
true
8
GO:0120303
120,303
visually-mediated background adaptation
biological_process
Any process in which an organism changes its pigmentation (lightening in response to a brighter environment or darkening in response to a dimmer environment) in response to a change in light intensity detected by melanopsin-expressing eye cells.
[ "GOC:cvs", "GOC:krc", "PMID:29239123", "PMID:32898924" ]
null
[]
[]
[]
[]
[]
[ "GO:0120302" ]
[]
[]
[]
[ "GO:0120302" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20524\" xsd:anyURI" ]
krc
2021-02-09T18:35:11Z
false
true
7
GO:0120304
120,304
integument-mediated background adaptation
biological_process
Any process in which an organism changes its pigmentation (lightening in response to a brighter environment or darkening in response to a dimmer environment) in response to a change in light intensity detected by light sensitive cells in the integument.
[ "GOC:cvs", "GOC:krc", "PMID:29239123", "PMID:32898924" ]
null
[]
[]
[]
[]
[]
[ "GO:0120302" ]
[]
[]
[]
[ "GO:0120302" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20524\" xsd:anyURI" ]
krc
2021-02-09T18:41:07Z
false
true
3
GO:0120305
120,305
regulation of pigmentation
biological_process
Any process that modulates the frequency, rate or extent of the deposition or modulates the distribution of coloring matter in an organism.
[ "GOC:krc" ]
null
[]
[]
[]
[]
[]
[ "GO:0050789" ]
[ "regulates GO:0043473" ]
[ "regulates" ]
[ "GO:0043473" ]
[ "GO:0043473", "GO:0050789" ]
[ "GO:0065007", "regulates GO:0043473" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20524\" xsd:anyURI" ]
krc
2021-02-09T19:37:35Z
false
true
3
GO:0120307
120,307
Hechtian strand
cellular_component
An extended membranous thread which firmly connects the plasma membrane to the cell wall during plasmolysis such that the plasma membrane does not separate from the cell wall completely.
[ "GOC:krc", "PMID:32397402" ]
null
[]
[]
[]
[]
[ "Wikipedia:Hechtian_strand" ]
[ "GO:0110165" ]
[]
[]
[]
[ "GO:0110165" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21138\" xsd:anyURI" ]
krc
2021-03-19T20:31:15Z
false
true
9
GO:0120308
120,308
axonemal outer doublet assembly
biological_process
The aggregation, arrangement and bonding together of a set of components to form an axonemal outer doublet, a part of an axoneme consisting of a doublet microtubule.
[ "GOC:ach", "GOC:krc", "PMID:16278296" ]
null
[ "axonemal outer doublet biogenesis", "axonemal outer doublet formation", "axonemal outer doublet morphogenesis", "axoneme outer doublet assembly", "outer doublet assembly", "outer-doublet microtubule assembly" ]
[ "EXACT", "EXACT", "EXACT", "EXACT", "BROAD", "BROAD" ]
[]
[]
[]
[ "GO:0022607" ]
[ "part_of GO:0035082" ]
[ "part_of" ]
[ "GO:0035082" ]
[ "GO:0022607", "GO:0035082" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21154\" xsd:anyURI" ]
krc
2021-03-23T16:28:18Z
false
true
8
GO:0120309
120,309
cilium attachment to cell body
biological_process
A process that is carried out at the cellular level which results in the lateral attachment of the cilium to the cell body via the flagellar attachment zone in some trypanosomatid species.
[ "GOC:ach", "GOC:krc", "PMID:11877446", "PMID:18820079", "PMID:22623724", "PMID:26272611" ]
null
[ "cilial attachment to cell body", "ciliary attachment to cell body", "flagellar attachment to cell body", "flagellum attachment to cell body" ]
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0016043" ]
[ "part_of GO:0044782" ]
[ "part_of" ]
[ "GO:0044782" ]
[ "GO:0016043", "GO:0044782" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21155\" xsd:anyURI" ]
krc
2021-03-23T18:01:14Z
false
true
6
GO:0120310
120,310
amastigogenesis
biological_process
The morphological, biochemical and genetic changes that induce the differentiation of metacyclic parasites into amastigotes in some of the Trypanosomatidae species such as Leishmania parasites and Trypanosoma cruzi. This process occurs inside the cells of the mammalian hosts, particularly in macrophages and other phago...
[ "DOI:10.5772/intechopen.84639", "GOC:ach", "GOC:krc", "PMID:12377273", "PMID:13129524", "PMID:26752404" ]
null
[]
[]
[]
[]
[]
[ "GO:0044114" ]
[]
[]
[]
[ "GO:0044114" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21156\" xsd:anyURI" ]
krc
2021-03-23T21:17:19Z
false
true
8
GO:0120311
120,311
ciliary pro-basal body maturation
biological_process
A process that is carried out at the cellular level which results in the conversion of an immature and partially assembled ciliary pro-basal body into a mature basal body that is capable of nucleating a cilium.
[ "GOC:ach", "GOC:krc", "PMID:26862392" ]
null
[ "flagellar pro-basal body maturation", "flagellar probasal body maturation", "pro-basal body maturation" ]
[ "RELATED", "RELATED", "RELATED" ]
[]
[]
[]
[ "GO:0022607", "GO:0032053" ]
[]
[]
[]
[ "GO:0022607", "GO:0032053" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21153\" xsd:anyURI" ]
krc
2021-03-26T17:41:59Z
false
true
8
GO:0120314
120,314
negative regulation of oocyte karyosome formation
biological_process
Any process that stops, prevents, or reduces the frequency, rate or extent of oocyte karyosome formation, the chromosome organization process in which meiotic chromosomes in the oocyte nucleus cluster together to form a compact spherical structure called the karyosome.
[ "GOC:ha", "GOC:krc", "PMID:33382409" ]
null
[]
[]
[]
[]
[]
[ "GO:0010948", "GO:0120313", "GO:2000242", "GO:2001251" ]
[ "negatively_regulates GO:0030717" ]
[ "negatively_regulates" ]
[ "GO:0030717" ]
[ "GO:0010948", "GO:0030717", "GO:0120313", "GO:2000242", "GO:2001251" ]
[ "GO:0065007", "negatively_regulates GO:0030717" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21298\" xsd:anyURI" ]
krc
2021-04-19T21:39:47Z
false
true
7
GO:0120315
120,315
positive regulation of oocyte karyosome formation
biological_process
Any process that activates or increases the frequency, rate or extent of oocyte karyosome formation, the chromosome organization process in which meiotic chromosomes in the oocyte nucleus cluster together to form a compact spherical structure called the karyosome.
[ "GOC:ha", "GOC:krc", "PMID:33382409" ]
null
[]
[]
[]
[]
[]
[ "GO:0090068", "GO:0120313", "GO:2000243", "GO:2001252" ]
[ "positively_regulates GO:0030717" ]
[ "positively_regulates" ]
[ "GO:0030717" ]
[ "GO:0030717", "GO:0090068", "GO:0120313", "GO:2000243", "GO:2001252" ]
[ "GO:0065007", "positively_regulates GO:0030717" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21298\" xsd:anyURI" ]
krc
2021-04-19T21:49:35Z
false
true
9
GO:0120316
120,316
sperm flagellum assembly
biological_process
The assembly and organization of the sperm flagellum, the microtubule-based axoneme and associated structures that are part of a sperm flagellum (or cilium).
[ "GOC:krc", "PMID:32791035" ]
null
[]
[]
[]
[]
[]
[ "GO:0003006", "GO:0044458" ]
[ "part_of GO:0007286", "part_of GO:0030317" ]
[ "part_of", "part_of" ]
[ "GO:0007286", "GO:0030317" ]
[ "GO:0003006", "GO:0007286", "GO:0030317", "GO:0044458" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21361\" xsd:anyURI" ]
krc
2021-04-29T01:27:27Z
false
true
3
GO:0120317
120,317
sperm mitochondrial sheath assembly
biological_process
The assembly and organization of the sperm mitochondrial sheath, the tightly packed helical sheath of ATP-producing mitochondria restricted to the midpiece of the sperm flagellum.
[ "GOC:krc", "PMID:32791035" ]
null
[]
[]
[]
[]
[]
[ "GO:0022607" ]
[ "part_of GO:0120316" ]
[ "part_of" ]
[ "GO:0120316" ]
[ "GO:0022607", "GO:0120316" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21361\" xsd:anyURI" ]
krc
2021-04-29T01:52:38Z
false
true
4
GO:0120319
120,319
long-chain fatty acid omega-1 hydroxylase activity
molecular_function
Catalysis of the reaction: an (omega-1)-ethyl long-chain fatty acid + O2 + reduced [NADPH-hemoprotein reductase] = an (omega-1)-hydroxy-long-chain fatty acid + H+ + H2O + oxidized [NADPH-hemoprotein reductase. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.
[ "GOC:nhn", "PMID:18577768", "PMID:22772592", "PMID:24242247", "RHEA:60936" ]
While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).
[ "cytochrome P450 fatty acid omega-1 hydroxylase activity" ]
[ "RELATED" ]
[]
[]
[ "RHEA:60928", "RHEA:60932", "RHEA:60936" ]
[ "GO:0120502" ]
[]
[]
[]
[ "GO:0120502" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:60936", "skos:narrowMatch RHEA:60928", "skos:narrowMatch RHEA:60932", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21648\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
krc
2021-06-21T18:31:38Z
false
true
8
GO:0120320
120,320
lateral pseudopodium retraction
biological_process
The myosin-based contraction and retraction of a lateral pseudopodium.
[ "GOC:krc", "GOC:pf", "PMID:12953059", "PMID:15483055", "PMID:17623773" ]
null
[ "lateral pseudopodium suppression" ]
[ "RELATED" ]
[]
[]
[]
[ "GO:0031270" ]
[]
[]
[]
[ "GO:0031270" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21600\" xsd:anyURI" ]
krc
2021-06-23T21:50:09Z
false
true
8
GO:0120321
120,321
nuclear envelope adjacent to nuclear pore complex
cellular_component
The region of the nuclear envelope situated in close proximity to a nuclear pore complex.
[ "GOC:mah", "PMID:21802294", "PMID:24184107" ]
null
[ "associated with the nuclear pore", "nuclear envelope adjacent to NPC", "nuclear envelope periphery of the nuclear pore complex" ]
[ "RELATED", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0110165" ]
[ "part_of GO:0005635" ]
[ "part_of" ]
[ "GO:0005635" ]
[ "GO:0005635", "GO:0110165" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21774\" xsd:anyURI" ]
krc
2021-07-07T20:30:21Z
false
true
8
GO:0120322
120,322
lipid modification by small protein conjugation
biological_process
A lipid modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to a target lipid.
[ "GOC:sp", "PMID:34012115" ]
null
[]
[]
[]
[]
[]
[ "GO:0030258" ]
[]
[]
[]
[ "GO:0030258" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21857\" xsd:anyURI" ]
krc
2021-07-20T18:53:03Z
false
true
7
GO:0120323
120,323
lipid ubiquitination
biological_process
The process in which one or more ubiquitin groups are added to a lipid.
[ "GOC:sp", "PMID:34012115" ]
null
[]
[]
[]
[]
[]
[ "GO:0120322" ]
[]
[]
[]
[ "GO:0120322" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21857\" xsd:anyURI" ]
krc
2021-07-20T18:58:34Z
false
true
8
GO:0120324
120,324
procyclogenesis
biological_process
The morphological, biochemical and genetic changes that induce the differentiation of bloodstream form trypomastigotes into procyclic trypomastigotes in some of the Trypanosomatidae species such as Trypanosoma brucei. This process occurs inside the midgut of the tsetse fly vectors in T. brucei.
[ "GOC:ach", "PMID:10593184", "PMID:1698624", "PMID:17997129", "PMID:3194362", "PMID:3194363" ]
null
[]
[]
[]
[]
[]
[ "GO:0044114" ]
[]
[]
[]
[ "GO:0044114" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21898\" xsd:anyURI" ]
krc
2021-08-03T19:53:17Z
false
true
1
GO:0120325
120,325
NuRD complex binding
molecular_function
Binding to a NuRD complex.
[ "GOC:krc", "GOC:lb", "PMID:25150861" ]
null
[]
[]
[]
[]
[]
[ "GO:0044877" ]
[]
[]
[]
[ "GO:0044877" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21845\" xsd:anyURI" ]
krc
2021-08-03T21:15:31Z
false
true
6
GO:0120326
120,326
appressorium-mediated entry into host
biological_process
Penetration by a symbiont into a host organism via an appressorium. The host is defined as the larger of the organisms involved in a symbiotic interaction.
[ "GOC:ach", "GOC:krc", "PMID:14731267", "PMID:22589729" ]
null
[ "appressorium-mediated host invasion", "appressorium-mediated host penetration", "appressorium-mediated invasion into host", "appressorium-mediated penetration into host" ]
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0044409" ]
[]
[]
[]
[ "GO:0044409" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21505\" xsd:anyURI" ]
krc
2021-08-04T00:48:35Z
false
true
2
GO:0120327
120,327
telopode
cellular_component
A telopode is a plasma membrane bounded cell projection that is present on a telocyte and is tens to hundreds of microns long. Telopodes form a labyrinthine system communicating through gap junctions.
[ "GOC:krc", "MESH:D000067617", "PMID:20367664" ]
null
[]
[]
[]
[]
[]
[ "GO:0120025" ]
[]
[]
[]
[ "GO:0120025" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21973\" xsd:anyURI" ]
krc
2021-08-16T16:45:21Z
false
true
8
GO:0120328
120,328
ATP-dependent DNA (cytosine-5-)-methyltransferase activity
molecular_function
Catalytic activity that acts to transfer a methyl group to a DNA molecule, driven by ATP hydrolysis.
[ "GOC:krc", "PMID:31955845", "PMID:32437639", "RHEA:68984" ]
null
[]
[]
[]
[]
[ "RHEA:68984" ]
[ "GO:0003886", "GO:0008094" ]
[]
[]
[]
[ "GO:0003886", "GO:0008094" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:68984", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21872\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30980\" xsd:anyURI" ]
krc
2021-08-16T21:00:16Z
false
true
3
GO:0120329
120,329
protein localization to centriolar satellite
biological_process
A process in which a protein is transported to, or maintained in, a location within a centriolar satellite.
[ "PMID:34782749" ]
null
[ "protein localisation to centriolar satellite" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0071539" ]
[]
[]
[]
[ "GO:0071539" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23064\" xsd:anyURI" ]
krc
2022-04-19T00:02:58Z
false
true
2
GO:0120332
120,332
host-mediated modulation of oral microbiota composition
biological_process
The biological process involved in maintaining the steady-state number of cells within a population of free-living cells, such as the bacteria, in the mouth.
[ "PMID:31882545" ]
null
[ "host-induced regulation of oral microbiota composition", "host-mediated regulation of oral microbiota composition" ]
[ "RELATED", "EXACT" ]
[]
[]
[]
[ "GO:0048872", "GO:0051851" ]
[]
[]
[]
[ "GO:0048872", "GO:0051851" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23569\" xsd:anyURI" ]
krc
2022-06-27T22:46:01Z
false
true
1
GO:0120333
120,333
radial spoke 1
cellular_component
The radial spoke of each group of radial spokes, whether grouped as triplets or doublets, that is most proximal to the base of the cilium. Radial spoke 1 (RS1), similarly to radial spoke 2, is comprised of four domains: 1) a very short base anchored to the A microtubule, 2) an elongaged stalk, 3) a bifurcated neck, and...
[ "GOC:krc", "PMID:22754630" ]
null
[ "RS1" ]
[ "RELATED" ]
[]
[]
[]
[ "GO:0001534" ]
[]
[]
[]
[ "GO:0001534" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25320\" xsd:anyURI" ]
krc
2023-04-26T22:13:01Z
false
true
3
GO:0120334
120,334
radial spoke 2
cellular_component
The radial spoke of each group of radial spokes, whether grouped as triplets or doublets, that is immediately distal to radial spoke 1 (RS1). Radial spoke 2 (RS2), similarly to RS1, is comprised of four domains: 1) a very short base anchored to the A microtubule, 2) an elongaged stalk, 3) a bifurcated neck, and 4) an o...
[ "GOC:krc", "PMID:22754630" ]
null
[ "RS2" ]
[ "RELATED" ]
[]
[]
[]
[ "GO:0001534" ]
[]
[]
[]
[ "GO:0001534" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25320\" xsd:anyURI" ]
krc
2023-04-26T22:14:02Z
false
true
9
GO:0120335
120,335
radial spoke 3
cellular_component
Radial spoke 3 (RS3), when present, is the most distal of each group of radial spokes, whether grouped as triplets or doublets. RS3 has significantly different morphology and protein composition than RS1 and RS2 and also extends at a slant from the microtubule doublet, rather than perpendicularly like RS1 and RS2. In s...
[ "GOC:krc", "ISBN:0124325653", "PMID:22754630", "PMID:25694453", "PMID:9450971" ]
null
[ "RS3" ]
[ "RELATED" ]
[]
[]
[]
[ "GO:0001534" ]
[]
[]
[]
[ "GO:0001534" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25320\" xsd:anyURI" ]
krc
2023-04-26T22:15:03Z
false
true
6
GO:0120336
120,336
radial spoke head 1
cellular_component
The portion of the radial spoke 1 that is orthogonal to the elongated stalk and which projects towards the central pair of microtubules within the ciliary axoneme.
[ "GOC:krc", "PMID:22754630", "PMID:348711799" ]
null
[ "radial spokehead 1" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0001535" ]
[ "part_of GO:0120333" ]
[ "part_of" ]
[ "GO:0120333" ]
[ "GO:0001535", "GO:0120333" ]
[ "GO:0001535", "part_of GO:0120333" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25320\" xsd:anyURI" ]
krc
2023-04-26T22:16:04Z
false
true
7
GO:0120337
120,337
radial spoke head 2
cellular_component
The portion of the radial spoke 2 that is orthogonal to the elongated stalk and which projects towards the central pair of microtubules within the ciliary axoneme.
[ "GOC:krc", "PMID:22754630", "PMID:348711799" ]
null
[ "radial spokehead 2" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0001535" ]
[ "part_of GO:0120334" ]
[ "part_of" ]
[ "GO:0120334" ]
[ "GO:0001535", "GO:0120334" ]
[ "GO:0001535", "part_of GO:0120334" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25320\" xsd:anyURI" ]
krc
2023-04-26T22:17:05Z
false
true
3
GO:0120338
120,338
radial spoke head 3
cellular_component
The portion of the radial spoke 3 that is orthogonal to the elongated stalk and which projects towards the central pair of microtubules within the ciliary axoneme.
[ "GOC:krc", "PMID:22754630", "PMID:348711799" ]
null
[ "radial spokehead 3" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0001535" ]
[ "part_of GO:0120335" ]
[ "part_of" ]
[ "GO:0120335" ]
[ "GO:0001535", "GO:0120335" ]
[ "GO:0001535", "part_of GO:0120335" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25320\" xsd:anyURI" ]
krc
2023-04-26T22:18:06Z
false
true
8
GO:0120339
120,339
radial spoke base
cellular_component
The short portion of the radial spoke that is directly anchored to the A microtubule of an axonemal microtubule doublet.
[ "GOC:krc", "PMID:22754630", "PMID:25694453" ]
null
[]
[]
[]
[]
[]
[ "GO:0032991" ]
[ "part_of GO:0001534" ]
[ "part_of" ]
[ "GO:0001534" ]
[ "GO:0001534", "GO:0032991" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25320\" xsd:anyURI" ]
krc
2023-04-26T22:19:07Z
false
true
9
GO:0120340
120,340
radial spoke base 1
cellular_component
The short portion of the radial spoke 1 (RS1) that is directly anchored to the A microtubule of an axonemal microtubule doublet.
[ "GOC:krc", "PMID:22754630", "PMID:25694453" ]
null
[]
[]
[]
[]
[]
[ "GO:0120339" ]
[ "part_of GO:0120333" ]
[ "part_of" ]
[ "GO:0120333" ]
[ "GO:0120333", "GO:0120339" ]
[ "GO:0120339", "part_of GO:0120333" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25320\" xsd:anyURI" ]
krc
2023-04-26T22:20:08Z
false
true
7
GO:0120341
120,341
radial spoke base 2
cellular_component
The short portion of the radial spoke 2 (RS2) that is directly anchored to the A microtubule of an axonemal microtubule doublet.
[ "GOC:krc", "PMID:22754630", "PMID:25694453" ]
null
[]
[]
[]
[]
[]
[ "GO:0120339" ]
[ "part_of GO:0120334" ]
[ "part_of" ]
[ "GO:0120334" ]
[ "GO:0120334", "GO:0120339" ]
[ "GO:0120339", "part_of GO:0120334" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25320\" xsd:anyURI" ]
krc
2023-04-26T22:21:09Z
false
true
6
GO:0120342
120,342
radial spoke base 3
cellular_component
The short portion of the radial spoke 3 (RS3 )that is directly anchored to the A microtubule of an axonemal microtubule doublet.
[ "GOC:krc", "PMID:22754630", "PMID:25694453" ]
null
[]
[]
[]
[]
[]
[ "GO:0120339" ]
[ "part_of GO:0120335" ]
[ "part_of" ]
[ "GO:0120335" ]
[ "GO:0120335", "GO:0120339" ]
[ "GO:0120339", "part_of GO:0120335" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25320\" xsd:anyURI" ]
krc
2023-04-26T22:22:10Z
false
true
3
GO:0120343
120,343
radial spoke neck
cellular_component
The radial spoke neck is a complex that connects the spoke stalk to the head.
[ "GOC:krc", "PMID:22754630" ]
null
[]
[]
[]
[]
[]
[ "GO:0032991" ]
[ "part_of GO:0001534" ]
[ "part_of" ]
[ "GO:0001534" ]
[ "GO:0001534", "GO:0032991" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25320\" xsd:anyURI" ]
krc
2023-04-26T22:23:11Z
false
true
7
GO:0120500
120,500
NAE1-UBA3 complex
cellular_component
A heterodimeric E1 complex that activates the ubiquitin-like protein NEDD8. In humans the subunits are NAE1 (also known as APPBP1) and UBA3.
[ "PMID:12740388", "PMID:21931660" ]
null
[ "APPBP1-UBA3 complex", "NAE", "NEDD8 activating enzyme" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:1902494" ]
[]
[]
[]
[ "GO:1902494" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27716\" xsd:anyURI" ]
sjm
2024-04-25T10:10:19Z
false
true
2
GO:0120501
120,501
F-actin monooxygenase activity
molecular_function
Catalysis of the reaction: L-methionyl-[F-actin] + NADPH + O2 + H+ = L-methionyl-(R)-S-oxide-[F-actin] + NADP+ + H2O.
[ "RHEA:51308" ]
null
[]
[]
[]
[]
[ "EC:1.14.13.225", "RHEA:24722", "RHEA:49676", "RHEA:51308" ]
[ "GO:0016709" ]
[]
[]
[]
[ "GO:0016709" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:1.14.13.225", "skos:exactMatch RHEA:51308", "skos:narrowMatch RHEA:24722", "skos:narrowMatch RHEA:49676", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27530\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:any...
sjm
2024-04-25T13:46:24Z
false
true
8
GO:0120502
120,502
fatty acid omega-1 hydroxylase activity
molecular_function
Catalysis of the reaction: an (omega-1)-ethyl fatty acid + O2 + reduced [NADPH--hemoprotein reductase] = an (omega-1)-hydroxy fatty acid + H+ + H2O + oxidized [NADPH--hemoprotein reductase].
[ "RHEA:44548" ]
null
[]
[]
[]
[]
[ "RHEA:39751", "RHEA:39759", "RHEA:44548" ]
[ "GO:0016712" ]
[]
[]
[]
[ "GO:0016712" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:44548", "skos:narrowMatch RHEA:39751", "skos:narrowMatch RHEA:39759", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24661\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
sjm
2024-04-26T10:00:25Z
false
true
5
GO:0120503
120,503
medium-chain fatty acid omega-1 hydroxylase activity
molecular_function
Catalysis of the reaction: an (omega-1)-ethyl medium-chain fatty acid + O2 + reduced [NADPH-hemoprotein reductase] = an (omega-1)-hydroxy-medium-chain fatty acid + H+ + H2O + oxidized [NADPH-hemoprotein reductase. A medium-chain fatty acid has an aliphatic tail containing 6 to 12 carbons.
[ "PMID:35934685" ]
While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).
[]
[]
[]
[]
[]
[ "GO:0120502" ]
[]
[]
[]
[ "GO:0120502" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24661\" xsd:anyURI" ]
sjm
2024-04-26T10:03:39Z
false
true
6
GO:0120504
120,504
EXT1-EXT2 complex
cellular_component
A heterodimeric complex capable of glycosyltransferase activity required for the elongation of heparan sulfate chains. In humans, the complex consists of EXT1 and EXT2. In Drosophila, the complex consists of ttv and sotv.
[ "GOC:sjm", "PMID:14998928", "PMID:36402845", "PMID:36593275" ]
null
[ "exostosin complex", "EXT1-EXT2 heparan sulfate biosynthesis complex" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:1990234" ]
[]
[]
[]
[ "GO:1990234" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27780\" xsd:anyURI" ]
sjm
2024-04-30T12:04:56Z
false
true
8
GO:0120505
120,505
histone H3K79 monomethyltransferase activity
molecular_function
Catalysis of the reaction: L-lysyl79-[histone H3] + S-adenosyl-L-methionine = H+ + N6-methyl-L-lysyl79-[histone H3] + S-adenosyl-L-homocysteine.
[ "PMID:14732680", "PMID:15371351", "RHEA:60332" ]
Comment: Note that the residue position corresponds to the canonical human H3 histone (UniProtKB:P84243); this residue is conserved across all eukaryotes. Residue 1 is the first residue following removal of the initiating Methionine (Met). Note that each histone is encoded by multiple genes, and sequences may vary acro...
[]
[]
[]
[]
[ "RHEA:60332" ]
[ "GO:0031151" ]
[]
[]
[]
[ "GO:0031151" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:60332", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26657\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30578\" xsd:anyURI" ]
sjm
2024-04-30T12:26:45Z
false
true
1
GO:0120507
120,507
tRNA-guanine transglycosylase complex
cellular_component
A protein complex that catalyzes the base-exchange of a guanine residue with queuine at the wobble position of the anticodon of tRNAs. The eukaryotic tRNA-guanine transglycosylase exists as a heterodimer of a catalytic subunit (QTRT1 in humans) and an accessory subunit (QTRT2 in humans), whereas the bacterial enzyme is...
[ "GOC:sjm", "PMID:20354154", "PMID:38181786" ]
null
[ "queuine tRNA-ribosyltransferase complex", "TGT" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:1990234" ]
[]
[]
[]
[ "GO:1990234" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27783\" xsd:anyURI" ]
sjm
2024-04-30T13:32:29Z
false
true
8
GO:0120508
120,508
GDP-mannose pyrophosphorylase complex
cellular_component
A protein complex capable of catalyzing the reaction of GTP and mannose-1-phosphate to form GDP-mannose. The complex is a homodimer in most bacteria and a heterodimer in most eukaryotes. In humans, it is composed of a catalytic beta subunit (GMPPB) and a regulatory alpha subunit (GMPPA).
[ "GOC:sjm", "PMID:33986552" ]
null
[ "GMPPA-GMPPB complex" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0061695" ]
[]
[]
[]
[ "GO:0061695" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27827\" xsd:anyURI" ]
sjm
2024-05-04T08:30:37Z
false
true
9
GO:0120511
120,511
methyl farnesoate epoxidase activity
molecular_function
Catalysis of the reaction: methyl (2E,6E)-farnesoate + O2 + reduced [NADPH--hemoprotein reductase] = H+ + H2O + juvenile hormone III + oxidized [NADPH--hemoprotein reductase].
[ "PMID:23586995", "PMID:38741075", "RHEA:43728" ]
null
[ "CYP15A1 activity" ]
[ "RELATED" ]
[]
[]
[ "EC:1.14.14.127", "MetaCyc:RXN-11621", "RHEA:43728" ]
[ "GO:0016712" ]
[]
[]
[]
[ "GO:0016712" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:1.14.14.127", "skos:exactMatch RHEA:43728", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27938\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
sjm
2024-05-23T12:38:07Z
false
true
9
GO:0120512
120,512
farnesoate epoxidase activity
molecular_function
Catalysis of the reaction: (2E,6E)-farnesoate + O2 + reduced [NADPH--hemoprotein reductase] = H+ + H2O + juvenile hormone III carboxylate + oxidized [NADPH--hemoprotein reductase].
[ "PMID:22412378", "PMID:38741075", "RHEA:43724" ]
null
[ "CYP15C1 activity" ]
[ "RELATED" ]
[]
[]
[ "EC:1.14.14.128", "MetaCyc:RXN-11770", "RHEA:43724" ]
[ "GO:0016712" ]
[]
[]
[]
[ "GO:0016712" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:1.14.14.128", "skos:exactMatch RHEA:43724", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27938\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
sjm
2024-05-23T12:38:32Z
false
true
8
GO:0120513
120,513
2-(3-amino-3-carboxypropyl)histidine synthase complex
cellular_component
A protein complex capable of catalysing the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L-methionine (SAM) to the histidine residue of translation elongation factor 2 (EF2), which is the first step in the biosynthesis of diphthamide. The complex is a Dph2 homodimer in archaea and a Dph1-Dph2 heterodim...
[ "GOC:sjm", "PMID:24422557", "PMID:31463593" ]
null
[ "Dph1-Dph2 complex" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:1990234" ]
[]
[]
[]
[ "GO:1990234" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27957\" xsd:anyURI" ]
sjm
2024-05-28T13:09:41Z
false
true
9
GO:0120514
120,514
2-hydroxyflavanone C-glucosyltransferase activity
molecular_function
Catalysis of the reaction: a 3'-hydro-2'-hydroxy-beta-oxodihydrochalcone + UDP-alpha-D-glucose = a 3'-(beta-D-glucopyranosyl)-2'-hydroxy-beta-oxodihydrochalcone + H+ + UDP.
[ "RHEA:51504" ]
null
[]
[]
[]
[]
[ "EC:2.4.1.360", "MetaCyc:RXN-18732", "RHEA:51504" ]
[ "GO:0016758" ]
[]
[]
[]
[ "GO:0016758" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:2.4.1.360", "skos:exactMatch MetaCyc:RXN-18732", "skos:exactMatch RHEA:51504", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28159\" xsd:anyURI" ]
sjm
2024-06-18T10:22:10Z
false
true
3
GO:0120515
120,515
fatty acid-CoA ligase activity
molecular_function
Catalysis of the reaction: a fatty acid + ATP + CoA = a fatty acyl-CoA + AMP + diphosphate.
[ "RHEA:38883" ]
null
[]
[]
[]
[]
[ "MetaCyc:BUTYRATE--COA-LIGASE-RXN", "RHEA:38883", "RHEA:44004" ]
[ "GO:0015645", "GO:0016405" ]
[]
[]
[]
[ "GO:0015645", "GO:0016405" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch MetaCyc:BUTYRATE--COA-LIGASE-RXN", "skos:exactMatch RHEA:38883", "skos:narrowMatch RHEA:44004", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28199\" xsd:anyURI" ]
sjm
2024-06-25T12:17:07Z
false
true
7
GO:0120516
120,516
diacylglycerol lipase activity
molecular_function
Catalysis of the reaction: a diacylglycerol + H2O = a fatty acid + a monoacylglycerol + H+.
[ "RHEA:32731" ]
null
[]
[]
[]
[]
[ "MetaCyc:RXN-19279", "RHEA:32731", "RHEA:44444", "RHEA:47868", "RHEA:78019" ]
[ "GO:0016298" ]
[]
[]
[]
[ "GO:0016298" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch EC:3.1.1.79", "skos:exactMatch MetaCyc:RXN-19279", "skos:exactMatch RHEA:32731", "skos:narrowMatch RHEA:44444", "skos:narrowMatch RHEA:47868", "skos:narrowMatch RHEA:78019", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28339\" xsd:anyURI" ]
sjm
2024-06-28T12:36:24Z
false
true
5
GO:0120518
120,518
protein N-terminal-methionine acetyltransferase activity
molecular_function
Catalysis of the reaction: acetyl-CoA + N-terminal L-methionyl-[protein] = CoA + H+ + N-terminal N(alpha)-acetyl-L-methionyl-[protein].
[ "RHEA:75239" ]
null
[ "peptide-methionine-alpha-N-acetyltransferase activity" ]
[ "EXACT" ]
[]
[]
[ "EC:2.3.1.254", "EC:2.3.1.256", "EC:2.3.1.258", "EC:2.3.1.259", "RHEA:50480", "RHEA:50484", "RHEA:50488", "RHEA:50492", "RHEA:50520", "RHEA:50524", "RHEA:50528", "RHEA:50532", "RHEA:50560", "RHEA:50564", "RHEA:50568", "RHEA:50572", "RHEA:50576", "RHEA:50580", "RHEA:50604", "RHE...
[ "GO:0004596" ]
[]
[]
[]
[ "GO:0004596" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:75239", "skos:narrowMatch EC:2.3.1.254", "skos:narrowMatch EC:2.3.1.256", "skos:narrowMatch EC:2.3.1.258", "skos:narrowMatch EC:2.3.1.259", "skos:narrowMatch RHEA:50480", "skos:narrowMatch RHEA:50484", "skos:narrowMatch RHEA:50488", "skos:narrowMatch RHEA:50492", "skos:narrow...
sjm
2024-07-10T12:16:39Z
false
true
2
GO:0120520
120,520
free fatty acid 2-hydroxylase activity
molecular_function
Catalysis of the reaction: a 1,2-saturated fatty acid + 2 Fe(II)-[cytochrome b5] + 2 H+ + O2 = a (R)-2-hydroxy fatty acid + 2 Fe(III)-[cytochrome b5] + H2O. Note that the substrate is a free fatty acid, not a fatty acyl chain within a sphingolipid.
[ "GOC:sjm", "RHEA:38855" ]
null
[]
[]
[]
[]
[ "RHEA:38551", "RHEA:38559", "RHEA:38855" ]
[ "GO:0080132" ]
[]
[]
[]
[ "GO:0080132" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:38855", "skos:narrowMatch RHEA:38551", "skos:narrowMatch RHEA:38559", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27541\" xsd:anyURI" ]
sjm
2024-07-12T08:40:48Z
false
true
4
GO:0120521
120,521
4-hydroxysphinganine ceramide fatty acyl 2-hydroxylase activity
molecular_function
Catalysis of the reaction: an N-(1,2 saturated acyl)-(4R)-hydroxysphinganine + 2 Fe(II)-[cytochrome b5] + 2 H+ + O2 = an N-(2R-hydroxyacyl)-4R-hydroxysphinganine + 2 Fe(III)-[cytochrome b5] + H2O.
[ "RHEA:46520" ]
null
[]
[]
[]
[]
[ "MetaCyc:RXN3O-4042", "RHEA:46520", "RHEA:64532" ]
[ "GO:0080132" ]
[]
[]
[]
[ "GO:0080132" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch EC:1.14.18.6", "skos:exactMatch MetaCyc:RXN3O-4042", "skos:exactMatch RHEA:46520", "skos:narrowMatch RHEA:64532", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27541\" xsd:anyURI" ]
sjm
2024-07-12T08:47:01Z
false
true
3
GO:0120522
120,522
short-chain fatty acyl-CoA oxidase activity
molecular_function
Catalysis of the reaction: a short-chain 2,3-saturated fatty acyl-CoA + O2 = a short-chain (2E)-enoyl-CoA + H2O2.
[ "RHEA:78859" ]
While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).
[]
[]
[]
[]
[ "RHEA:41964", "RHEA:66200", "RHEA:78859" ]
[ "GO:0003997" ]
[]
[]
[]
[ "GO:0003997" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:78859", "skos:narrowMatch RHEA:41964", "skos:narrowMatch RHEA:66200", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28733\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
sjm
2024-08-27T08:19:22Z
false
true
7
GO:0120523
120,523
medium-chain fatty acyl-CoA oxidase activity
molecular_function
Catalysis of the reaction: a medium-chain 2,3-saturated fatty acyl-CoA + O2 = a medium-chain (2E)-enoyl-CoA + H2O2.
[ "RHEA:78855" ]
While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).
[]
[]
[]
[]
[ "RHEA:38987", "RHEA:40171", "RHEA:40175", "RHEA:40179", "RHEA:40311", "RHEA:66204", "RHEA:78855" ]
[ "GO:0003997" ]
[]
[]
[]
[ "GO:0003997" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:78855", "skos:narrowMatch RHEA:38987", "skos:narrowMatch RHEA:40171", "skos:narrowMatch RHEA:40175", "skos:narrowMatch RHEA:40179", "skos:narrowMatch RHEA:40311", "skos:narrowMatch RHEA:66204", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28733\" xsd:an...
sjm
2024-08-27T08:21:49Z
false
true
3
GO:0120524
120,524
long-chain fatty acyl-CoA oxidase activity
molecular_function
Catalysis of the reaction: a long-chain 2,3-saturated fatty acyl-CoA + O2 = a long-chain (2E)-enoyl-CoA + H2O2.
[ "RHEA:78851" ]
While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).
[]
[]
[]
[]
[ "RHEA:38971", "RHEA:40167", "RHEA:40183", "RHEA:69643", "RHEA:78571", "RHEA:78587", "RHEA:78851", "RHEA:83059" ]
[ "GO:0003997" ]
[]
[]
[]
[ "GO:0003997" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:78851", "skos:narrowMatch RHEA:38971", "skos:narrowMatch RHEA:40167", "skos:narrowMatch RHEA:40183", "skos:narrowMatch RHEA:69643", "skos:narrowMatch RHEA:78571", "skos:narrowMatch RHEA:78587", "skos:narrowMatch RHEA:83059", "term_tracker_item \"https://github.com/geneontology/...
sjm
2024-08-27T08:24:03Z
false
true
5
GO:0120525
120,525
choline trimethylamine lyase activity
molecular_function
Catalysis of the reaction: choline = acetaldehyde + trimethylamine.
[ "RHEA:35095" ]
null
[]
[]
[]
[]
[ "EC:4.3.99.4", "KEGG_REACTION:R10285", "MetaCyc:RXN-13946", "RHEA:35095" ]
[ "GO:0016840" ]
[]
[]
[]
[ "GO:0016840" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:4.3.99.4", "skos:exactMatch KEGG_REACTION:R10285", "skos:exactMatch MetaCyc:RXN-13946", "skos:exactMatch RHEA:35095", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28808\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/315...
sjm
2024-08-30T13:13:55Z
false
true
8
GO:0120526
120,526
homomethionine N-monooxygenase activity
molecular_function
Catalysis of the reaction: an L-polyhomomethionine + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = an (E)-omega-(methylsulfanyl)-alkanal oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase].
[ "RHEA:51972" ]
null
[]
[]
[]
[]
[ "EC:1.14.14.42", "KEGG_REACTION:R11646", "MetaCyc:RXN-18175", "RHEA:32719", "RHEA:32723", "RHEA:33243", "RHEA:33291", "RHEA:33295", "RHEA:51972" ]
[ "GO:0016712" ]
[]
[]
[]
[ "GO:0016712" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:1.14.14.42", "skos:exactMatch KEGG_REACTION:R11646", "skos:exactMatch MetaCyc:RXN-18175", "skos:exactMatch RHEA:51972", "skos:narrowMatch RHEA:32719", "skos:narrowMatch RHEA:32723", "skos:narrowMatch RHEA:33243", "skos:narrowMatch RHEA:33291", "skos:narrowMatch RHEA:33295", "te...
sjm
2024-09-05T07:47:05Z
false
true
6
GO:0120528
120,528
2-(omega-methylthio)alkylmalate dehydratase activity
molecular_function
Catalysis of the reactions: a 2-(omega-methylsulfanyl)alkylmalate = a 2-(omega-methylsulfanyl)alkylmaleate + H2O and a 3-(omega-methylsulfanyl)alkylmalate = a 2-(omega-methylsulfanyl)alkylmaleate + H2O.
[ "EC:4.2.1.170" ]
null
[]
[]
[]
[]
[ "EC:4.2.1.170", "RHEA:50632", "RHEA:50636" ]
[ "GO:0016836" ]
[]
[]
[]
[ "GO:0016836" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:4.2.1.170", "skos:narrowMatch RHEA:50632", "skos:narrowMatch RHEA:50636", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28776\" xsd:anyURI" ]
sjm
2024-09-05T08:00:08Z
false
true
1
GO:0120529
120,529
secoisolariciresinol dehydrogenase activity
molecular_function
Catalysis of the reaction: (-)-secoisolariciresinol + 2 NAD+ = (-)-matairesinol + 2 H(+) + 2 NADH.
[ "RHEA:33887" ]
null
[]
[]
[]
[]
[ "EC:1.1.1.331", "KEGG_REACTION:R10129", "MetaCyc:RXN-13433", "RHEA:33887" ]
[ "GO:0016616" ]
[]
[]
[]
[ "GO:0016616" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:1.1.1.331", "skos:exactMatch KEGG_REACTION:R10129", "skos:exactMatch MetaCyc:RXN-13433", "skos:exactMatch RHEA:33887", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28776\" xsd:anyURI" ]
sjm
2024-09-05T08:19:32Z
false
true
5
GO:0120530
120,530
UDP-alpha-D-glucose biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of UDP-alpha-D-glucose, a substance composed of alpha-D-glucose in glycosidic linkage with uridine diphosphate.
[ "MetaCyc:PWY-7343" ]
null
[ "UDP-D-glucose biosynthesis", "UDP-D-glucose biosynthetic process", "UDP-glucose biosynthesis", "uridine diphosphate glucose biosynthesis", "uridine diphosphate glucose biosynthetic process" ]
[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[ "MetaCyc:PWY-7343" ]
[ "GO:0006011", "GO:0009226" ]
[]
[]
[]
[ "GO:0006011", "GO:0009226" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28951\" xsd:anyURI" ]
sjm
2024-09-18T14:01:05Z
false
true
9
GO:0120531
120,531
prenyl diphosphate synthase activity
molecular_function
Catalysis of chain elongation of prenyl diphosphate substrates via one or more condensation reactions with isopentenyl diphosphate to generate linear polymers with defined chain lengths.
[ "PMID:12135472", "PMID:26216239" ]
null
[ "IPPS activity", "isoprenyl pyrophosphate synthase activity" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0004659" ]
[]
[]
[]
[ "GO:0004659" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch EC:2.5.1.-", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20661\" xsd:anyURI" ]
sjm
2024-11-22T10:52:31Z
false
true
3
GO:0120532
120,532
glycosaminoglycan-protein linkage region biosynthetic process
biological_process
The formation of a tetrasaccharide linker sequence (xylose-galactose-galactose-glucuronate) on specific serine residues of a core protein, on to which dermatan sulfate, chondroitin sulfate, heparan sulfate or heparin glycosaminoglycans may be assembled to synthesise the corresponding proteoglycan.
[ "MetaCyc:PWY-6557" ]
null
[ "Glycosaminoglycan biosynthesis, linkage tetrasaccharide", "glycosaminoglycan-protein linkage region biosynthesis" ]
[ "EXACT", "EXACT" ]
[]
[]
[ "MetaCyc:PWY-6557", "Reactome:R-HSA-1971475 \"Glycosaminoglycan-protein linkage region biosynthesis\"" ]
[ "GO:0180064" ]
[ "part_of GO:0015012", "part_of GO:0030210", "part_of GO:0050650", "part_of GO:0050651" ]
[ "part_of", "part_of", "part_of", "part_of" ]
[ "GO:0015012", "GO:0030210", "GO:0050650", "GO:0050651" ]
[ "GO:0015012", "GO:0030210", "GO:0050650", "GO:0050651", "GO:0180064" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28977\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29294\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30378\" xsd:anyURI" ]
sjm
2024-11-27T13:13:42Z
false
true
4
GO:0120534
120,534
dermatan sulfotransferase activity
molecular_function
Catalysis of the reaction: 3'-phosphoadenylyl sulfate + dermatan = adenosine 3',5'-bisphosphate + dermatan sulfate.
[ "GOC:curators" ]
null
[]
[]
[]
[]
[]
[ "GO:0050698" ]
[]
[]
[]
[ "GO:0050698" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch EC:2.8.2.-", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28380\" xsd:anyURI" ]
sjm
2024-12-02T12:14:06Z
false
true
5
GO:0120536
120,536
heptaprenylglyceryl phosphate synthase activity
molecular_function
Catalysis of the reaction: sn-glycerol 1-phosphate + all-trans-heptaprenyl diphosphate = 3-heptaprenyl-sn-glycero-1-phosphate + diphosphate.
[ "PMID:21761520", "RHEA:33495" ]
null
[ "glycerol-1-phosphate heptaprenyltransferase activity", "HepGP synthase activity" ]
[ "EXACT", "EXACT" ]
[]
[]
[ "EC:2.5.1.n9", "RHEA:33495" ]
[ "GO:0004659" ]
[]
[]
[]
[ "GO:0004659" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:2.5.1.n9", "skos:exactMatch RHEA:33495", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29426\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
sjm
2024-12-12T10:57:45Z
false
true
2
GO:0120537
120,537
3-demethylubiquinone 3-O-methyltransferase activity
molecular_function
Catalysis of the reaction: a 3-demethylubiquinone + S-adenosyl-L-methionine = a ubiquinone + S-adenosyl-L-homocysteine.
[ "PMID:38425362", "RHEA:81215" ]
null
[]
[]
[]
[]
[ "RHEA:81215" ]
[ "GO:0008171", "GO:0008757" ]
[ "part_of GO:0006744" ]
[ "part_of" ]
[ "GO:0006744" ]
[ "GO:0006744", "GO:0008171", "GO:0008757" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:81215", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29459\" xsd:anyURI" ]
sjm
2024-12-18T09:25:15Z
false
true
2
GO:0120538
120,538
2-methoxy-6-polyprenolphenol 4-hydroxylase activity
molecular_function
Catalysis of the reaction: 2-methoxy-6-(all-trans-polyprenyl)phenol + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H+ = 2-methoxy-6-(all-trans-polyprenyl)benzene-1,4-diol + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O.
[ "PMID:38425362", "RHEA:81183" ]
null
[]
[]
[]
[]
[ "EC:1.14.15.46", "RHEA:81183", "RHEA:81279", "RHEA:81283", "RHEA:81287", "RHEA:81291", "RHEA:81295" ]
[ "GO:0016713" ]
[ "part_of GO:0006744" ]
[ "part_of" ]
[ "GO:0006744" ]
[ "GO:0006744", "GO:0016713" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:1.14.15.46", "skos:exactMatch RHEA:81183", "skos:narrowMatch RHEA:81279", "skos:narrowMatch RHEA:81283", "skos:narrowMatch RHEA:81287", "skos:narrowMatch RHEA:81291", "skos:narrowMatch RHEA:81295", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29459\" xsd:...
sjm
2024-12-18T09:30:52Z
false
true
4
GO:0120539
120,539
4-hydroxy-3-methoxy-5-polyprenylbenzoate decarboxylase activity
molecular_function
Catalysis of the reaction: a 4-hydroxy-3-methoxy-5-(all-trans-polyprenyl)benzoate + H+ = a 2-methoxy-6-(all-trans-polyprenyl)phenol + CO2.
[ "PMID:38295803", "PMID:38425362", "RHEA:81179" ]
null
[]
[]
[]
[]
[ "EC:4.1.1.130", "Reactome:R-HSA-2162195 \"COQ4 decarboxylates MHDB\"", "RHEA:44768", "RHEA:81179", "RHEA:81263", "RHEA:81267", "RHEA:81271", "RHEA:81275" ]
[ "GO:0016831" ]
[ "part_of GO:0006744" ]
[ "part_of" ]
[ "GO:0006744" ]
[ "GO:0006744", "GO:0016831" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:4.1.1.130", "skos:exactMatch RHEA:81179", "skos:narrowMatch RHEA:44768", "skos:narrowMatch RHEA:81263", "skos:narrowMatch RHEA:81267", "skos:narrowMatch RHEA:81271", "skos:narrowMatch RHEA:81275", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29459\" xsd:a...
sjm
2024-12-18T09:36:09Z
false
true
1
GO:0120540
120,540
obsolete chondroitin sulfate proteoglycan biosynthetic process, enzymatic modification
biological_process
OBSOLETE. The modification, often by sulfation, of sugars in the polysaccharide chain component of chondroitin sulfate proteoglycans.
[ "PMID:38500384" ]
This term was obsoleted because it is a subprocess of chondroitin sulfate proteoglycan biosynthetic process ; GO:0050650.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0050650" ]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28977\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29294\" xsd:anyURI" ]
sjm
2024-12-18T12:23:24Z
true
true
2
GO:0120541
120,541
obsolete dermatan sulfate proteoglycan biosynthetic process, enzymatic modification
biological_process
OBSOLETE. The modification, often by sulfation, of sugars in the polysaccharide chain component of dermatan sulfate proteoglycans.
[ "PMID:38500384" ]
This term was obsoleted because it is a subprocess of dermatan sulfate proteoglycan biosynthetic process ; GO:0050651.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0050651" ]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28977\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29294\" xsd:anyURI" ]
sjm
2024-12-18T12:26:36Z
true
true
4
GO:0120542
120,542
ethanol dehydrogenase (NAD+) activity
molecular_function
Catalysis of the reaction: ethanol + NAD+ = acetaldehyde + NADH + H+.
[ "RHEA:25290" ]
null
[]
[]
[]
[]
[ "RHEA:25290" ]
[ "GO:0004022" ]
[]
[]
[]
[ "GO:0004022" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:25290", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29540\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
sjm
2025-01-16T08:15:42Z
false
true
2
GO:0120543
120,543
macromolecular conformation isomerase activity
molecular_function
Catalysis of a reaction that alters the macromolecular conformation of a molecule.
[ "EC:5.6.-.-" ]
null
[]
[]
[]
[]
[ "EC:5.6.-.-" ]
[ "GO:0016853" ]
[]
[]
[]
[ "GO:0016853" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:5.6.-.-", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29690\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
sjm
2025-02-11T09:46:30Z
false
true
5
GO:0120544
120,544
polypeptide conformation or assembly isomerase activity
molecular_function
Catalysis of a reaction that alters the conformation or assembly of a polypeptide.
[ "EC:5.6.1.-" ]
null
[]
[]
[]
[]
[ "EC:5.6.1.-" ]
[ "GO:0120543" ]
[]
[]
[]
[ "GO:0120543" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:5.6.1.-", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29690\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
sjm
2025-02-11T09:51:11Z
false
true
9
GO:0120546
120,546
oxidoreductase activity, reducing C-O-C group as acceptor
molecular_function
Catalysis of an oxidation-reduction (redox) reaction in which a reducing C-O-C group acts as acceptor.
[ "EC:1.23.-.-" ]
null
[]
[]
[]
[]
[ "EC:1.23.-.-" ]
[ "GO:0016491" ]
[]
[]
[]
[ "GO:0016491" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:1.23.-.-", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29701\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
sjm
2025-02-11T18:09:07Z
false
true
8
GO:0120547
120,547
heme A synthase activity
molecular_function
Catalysis of the reaction: Fe(II)-heme o + 2 acceptor + H2O = Fe(II)-heme a + 2 acceptor-H2. The conversion of heme o to heme a occcurs by two successive hydroxylations of the methyl group at C8 using water as the oxygen source. The first hydroxylation forms heme i, the second hydroxylation results in an unstable dihyd...
[ "PMID:30397130", "RHEA:63388" ]
null
[]
[]
[]
[]
[ "EC:1.17.99.9", "MetaCyc:RXN-18399", "Reactome:R-HSA-2995334 \"COX15 transforms heme O to heme A\"", "RHEA:63388" ]
[ "GO:0016725" ]
[]
[]
[]
[ "GO:0016725" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:1.17.99.9", "skos:exactMatch MetaCyc:RXN-18399", "skos:exactMatch RHEA:63388", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29711\" xsd:anyURI" ]
sjm
2025-02-13T12:39:18Z
false
true
1
GO:0120549
120,549
limit dextrin alpha-1,6-maltotetraose-hydrolase activity
molecular_function
Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages to branches with degrees of polymerization of three or four glucose residues in limit dextrin.
[ "EC:3.2.1.196" ]
null
[ "glycogen debranching enzyme" ]
[ "EXACT" ]
[]
[]
[ "EC:3.2.1.196", "MetaCyc:RXN0-5146" ]
[ "GO:0004553" ]
[]
[]
[]
[ "GO:0004553" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:3.2.1.196", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29864\" xsd:anyURI" ]
sjm
2025-03-06T06:46:46Z
false
true
5
GO:0120550
120,550
methyltransferase cap2 activity
molecular_function
Catalysis of the reaction: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-ribonucleoside)-(ribonucleotide) in mRNA or snRNA + S-adenosyl-L-methionine = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-ribonucleoside)-(2'-O-methyl-ribonucleotide) in mRNA or snRNA + S-adenosyl-L-homocysteine + H+. T...
[ "EC:2.1.1.296" ]
null
[ "cap2-MTase activity", "mRNA (nucleoside-2'-O-)-methyltransferase activity" ]
[ "EXACT", "RELATED" ]
[]
[]
[ "EC:2.1.1.296", "MetaCyc:RXN-14928", "RHEA:67024" ]
[ "GO:0008171", "GO:0008173" ]
[]
[]
[]
[ "GO:0008171", "GO:0008173" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:2.1.1.296", "skos:narrowMatch MetaCyc:RXN-14928", "skos:narrowMatch RHEA:67024", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27387\" xsd:anyURI" ]
sjm
2025-03-20T17:49:48Z
false
true
3
GO:0120551
120,551
2-oxoglutarate decarboxylation to succinyl-CoA
biological_process
The chemical reactions and pathways resulting in the formation of succinyl-CoA from 2-oxoglutarate. In most organisms, this pathway is part of the TCA cycle and comprises a series of three reactions carried out by a multisubunit complex called the '2-oxoglutarate dehydrogenase complex', even though 2-oxoglutarate dehy...
[ "MetaCyc:PWY-5084" ]
null
[ "2-ketoglutarate dehydrogenase system", "2-oxoglutarate dehydrogenase system", "2alpha-ketoglutarate dehydrogenase system" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[ "MetaCyc:PWY-5084" ]
[ "GO:0006103", "GO:1901290" ]
[ "part_of GO:0006099" ]
[ "part_of" ]
[ "GO:0006099" ]
[ "GO:0006099", "GO:0006103", "GO:1901290" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29951\" xsd:anyURI" ]
sjm
2025-04-01T14:31:01Z
false
true
1
GO:0120552
120,552
branched-chain alpha-keto acid decarboxylation to branched-chain acyl-CoA
biological_process
The chemical reactions and pathways resulting in the formation of a branched-chain acyl-CoA by the oxidative decarboxylation of a branched-chain alpha-keto acid derived from L-leucine, L-isoleucine or L-valine. This pathway comprises a series of three reactions carried out by a multisubunit complex called the 'branched...
[ "MetaCyc:PWY-5046" ]
null
[ "branched-chain 2-oxo acid dehydrogenase system", "branched-chain alpha-keto acid dehydrogenase system" ]
[ "EXACT", "EXACT" ]
[]
[]
[ "MetaCyc:PWY-5046" ]
[ "GO:0019752", "GO:0035337" ]
[ "part_of GO:0009083" ]
[ "part_of" ]
[ "GO:0009083" ]
[ "GO:0009083", "GO:0019752", "GO:0035337" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29951\" xsd:anyURI" ]
sjm
2025-04-01T15:15:40Z
false
true
6
GO:0120553
120,553
farnesal dehydrogenase (NAD+) activity
molecular_function
Catalysis of the reaction: (2E,6E)-farnesal + NAD+ + H2O = (2E,6E)-farnesoate + NADH + 2 H+.
[ "PMID:23639754", "RHEA:24216" ]
null
[]
[]
[]
[]
[ "EC:1.2.1.94", "MetaCyc:RXN-11619", "RHEA:24216" ]
[ "GO:0004029" ]
[]
[]
[]
[ "GO:0004029" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:1.2.1.94", "skos:exactMatch MetaCyc:RXN-11619", "skos:exactMatch RHEA:24216", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30259\" xsd:anyURI" ]
sjm
2025-05-15T14:18:24Z
false
true
9
GO:0120554
120,554
(2S)-2-aminobutanoate:2-oxoglutarate transaminase activity
molecular_function
Catalysis of the reaction: (2S)-2-aminobutanoate + 2-oxoglutarate = 2-oxobutanoate + L-glutamate.
[ "PMID:27827456", "RHEA:70223" ]
null
[ "2-aminobutanoate transaminase activity" ]
[ "EXACT" ]
[]
[]
[ "MetaCyc:RXN-20408", "RHEA:70223" ]
[ "GO:0008483" ]
[]
[]
[]
[ "GO:0008483" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch MetaCyc:RXN-20408", "skos:exactMatch RHEA:70223", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30260\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31140\" xsd:anyURI" ]
sjm
2025-05-15T14:38:07Z
false
true
9
GO:0120556
120,556
polyprenyl diphosphate phosphatase activity
molecular_function
Catalysis of the dephosphorylation of polyprenyl diphosphates.
[ "GOC:curators" ]
null
[]
[]
[]
[]
[]
[ "GO:0106405" ]
[]
[]
[]
[ "GO:0106405" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30245\" xsd:anyURI" ]
sjm
2025-05-23T11:54:19Z
false
true
7
GO:0120557
120,557
farnesyl diphosphatase activity
molecular_function
Catalysis of the reaction: (2E,6E)-farnesyl diphosphate + H2O = (2E,6E)-farnesyl phosphate + phosphate + H+.
[ "PMID:19168029", "RHEA:48128" ]
null
[]
[]
[]
[]
[ "MetaCyc:RXN-11776", "RHEA:48128" ]
[ "GO:0120556" ]
[]
[]
[]
[ "GO:0120556" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch EC:3.6.1.68", "skos:exactMatch RHEA:48128", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30245\" xsd:anyURI" ]
sjm
2025-05-23T12:00:24Z
false
true
9
GO:0120558
120,558
lysophospholipase A1 activity
molecular_function
Catalysis of the hydrolysis of a lysoglycerophospholipid, removing the acyl chain at the sn-1 position to yield a glycerophospho-compound and a free fatty acid.
[ "GOC:curators" ]
null
[]
[]
[]
[]
[]
[ "GO:0140322" ]
[]
[]
[]
[ "GO:0140322" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30258\" xsd:anyURI" ]
sjm
2025-05-23T13:08:06Z
false
true
8
GO:0120559
120,559
phosphatidylethanolamine lysophospholipase A1 activity
molecular_function
Catalysis of the reaction: a 1-acyl-sn-glycero-3-phosphoethanolamine + H2O = sn-glycero-3-phosphoethanolamine + a fatty acid + H+.
[ "RHEA:32967" ]
null
[ "phosphatidylethanolamine lysophospholipase A1-type activity", "phosphatidylethanolamine lysophospholipase activity" ]
[ "EXACT", "BROAD" ]
[]
[]
[ "RHEA:32967" ]
[ "GO:0120558" ]
[]
[]
[]
[ "GO:0120558" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:32967", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30258\" xsd:anyURI" ]
sjm
2025-05-23T13:15:13Z
false
true
1
GO:0120560
120,560
phosphatidylserine lysophospholipase A1 activity
molecular_function
Catalysis of the reaction: a 1-acyl-sn-glycero-3-phospho-L-serine + H2O = sn-glycero-3-phospho-L-serine + a fatty acid + H+.
[ "RHEA:32979" ]
null
[ "phosphatidylserine lysophospholipase A1-type activity", "phosphatidylserine sn-1 acylhydrolase", "phosphatidylserine-specific phospholipase A1" ]
[ "EXACT", "RELATED", "RELATED" ]
[]
[]
[ "MetaCyc:RXN-20544", "RHEA:32979", "RHEA:51184" ]
[ "GO:0120558" ]
[]
[]
[]
[ "GO:0120558" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch EC:3.1.1.111", "skos:exactMatch RHEA:32979", "skos:narrowMatch RHEA:51184", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30258\" xsd:anyURI" ]
sjm
2025-05-23T13:15:28Z
false
true
4