LiteFold/GO · Datasets at Hugging Face

GO:1990379

1,990,379

lipid transport across blood-brain barrier

biological_process

The directed movement of lipid molecules passing through the blood-brain barrier.

[ "GOC:sjp", "PMID:24345162" ]

null

[ "lipid transport across blood brain barrier" ]

[ "EXACT" ]

[]

[ "GO:0006869", "GO:0150104" ]

[]

[ "GO:0006869", "GO:0150104" ]

[]

sjp

2014-05-08T09:52:28Z

false

true

2

GO:1990380

1,990,380

K48-linked deubiquitinase activity

molecular_function

Hydrolysis of a ubiquitin unit from a ubiquitinated protein linked via the Lys48 residue of ubiquitin.

[ "GOC:bf", "GOC:PARL", "PMID:22970133" ]

null

[ "K48-specific deubiquitinase activity", "K48-specific deubiquitinating activity", "Lys48-specific deubiquitinase activity" ]

[ "EXACT", "EXACT", "EXACT" ]

[]

[ "Reactome:R-HSA-5690870 \"OTUD7B,TNFAIP3 deubiquitinate TRAF6\"", "Reactome:R-HSA-9711058 \"SARS-CoV-1 nsp3 deubiquinates K48-linked pUb IkBA\"" ]

[ "GO:0101005" ]

[]

[ "GO:0101005" ]

[]

bf

2014-05-15T14:31:07Z

false

true

5

GO:1990381

1,990,381

ubiquitin-specific protease binding

molecular_function

Binding to a ubiquitin-specific protease.

[ "GOC:bf", "GOC:PARL", "PMID:24063750" ]

null

[ "deubiquitinase binding", "deubiquitinating enzyme binding" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0002020" ]

[]

[ "GO:0002020" ]

[]

bf

2014-05-19T10:01:53Z

false

true

2

GO:1990382

1,990,382

obsolete melanosome assembly

biological_process

OBSOLETE. The aggregation, arrangement and bonding together of a set of components to form a melanosome, a tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored.

[ "GOC:bf", "GOC:PARL", "PMID:22511774" ]

This term was obsoleted at the TermGenie Gatekeeper stage.

[ "melanosome biogenesis" ]

[ "EXACT" ]

[]

bf

2014-05-20T16:06:04Z

true

4

GO:1990383

1,990,383

cellular response to biotin starvation

biological_process

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of biotin.

[ "PMID:12557275" ]

null

[]

[ "GO:0009267" ]

[]

[ "GO:0009267" ]

[]

al

2014-05-21T10:06:58Z

false

true

8

GO:1990384

1,990,384

hyaloid vascular plexus regression

biological_process

The developmental process in which the hyaloid vascular plexus is destroyed as a part of its normal progression.

[ "GOC:hjd", "PMID:18841878" ]

null

[]

[ "GO:0060033" ]

[ "part_of GO:0043010" ]

[ "part_of" ]

[ "GO:0043010" ]

[ "GO:0043010", "GO:0060033" ]

[]

hjd

2014-05-28T18:43:21Z

false

true

7

GO:1990386

1,990,386

mitotic cleavage furrow ingression

biological_process

Advancement of the mitotic cleavage furrow from the outside of the cell inward towards the center of the cell. The cleavage furrow acts as a 'purse string' which draws tight to separate daughter cells during mitotic cytokinesis and partition the cytoplasm between the two daughter cells. The furrow ingresses until a cyt...

[ "GOC:kmv", "PMID:12707312" ]

null

[]

[ "GO:0036090", "GO:1902410" ]

[]

[ "GO:0036090", "GO:1902410" ]

[]

kmv

2014-05-29T20:58:27Z

false

true

2

GO:1990387

1,990,387

isogloboside biosynthetic process

biological_process

The chemical reactions and pathways resulting in the formation of isogobliosides that begins with the synthesis of a tetrasaccharide core GalNAc-beta-1,3Gal-alpha-1,3Gal-beta-1,4Glc-ceramide. This core can be further elongated with the sequential addition of various carbohydrate units.

[ "PMID:35536927" ]

null

[ "isoglobo-series glycosphingolipid biosynthesis" ]

[ "EXACT" ]

[]

[ "GO:0006688", "GO:0046513" ]

[]

[ "GO:0006688", "GO:0046513" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30616\" xsd:anyURI" ]

hjd

2014-05-30T17:36:51Z

false

true

5

GO:1990389

1,990,389

CUE1-UBC7 ubiquitin-conjugating enzyme complex

cellular_component

A protein complex capable of ubiquitin-conjugating enzyme activity during ER-associated protein degradation (ERAD). In S. cerevisiae, UBC7 is the ubiquitin-conjugating enzyme (E2) and requires binding to the ER surface by CUE1.

[ "GOC:bhm", "PMID:23028185" ]

An example of this is UBC7 in Saccharomyces cerevisiae (Q02159) in PMID:16179953 (inferred from direct assay).

[ "CUE1-UBC7 ubiquitin-conjugating enzyme (E2)" ]

[ "EXACT" ]

[]

[ "GO:0000835", "GO:0031371" ]

[]

[ "GO:0000835", "GO:0031371" ]

[]

bhm

2014-06-02T15:35:58Z

false

true

1

GO:1990390

1,990,390

protein K33-linked ubiquitination

biological_process

A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 33 of the ubiquitin monomers, is added to a protein.

[ "PMID:24768539" ]

null

[]

[ "GO:0000209" ]

[]

[ "GO:0000209" ]

[]

sp

2014-06-03T12:22:05Z

false

true

3

GO:1990391

1,990,391

DNA repair complex

cellular_component

A protein complex involved in DNA repair processes including direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.

[ "GOC:bhm", "PMID:17217467", "PMID:20551348", "PMID:22749910", "PMID:24192350" ]

null

[ "DNA damage repair complex", "WHY1 complex" ]

[ "EXACT", "NARROW" ]

[]

[ "GO:1902494" ]

[]

[ "GO:1902494" ]

[]

bhm

2014-06-04T09:15:24Z

false

true

2

GO:1990392

1,990,392

EFF-1 complex

cellular_component

A trimeric cell-cell fusion complex that serves as a scaffold for zippering up the extracellular domains, bringing the transmembrane segments into close proximity such that they can continue zippering within the two membranes into one. Two prefusion monomers cluster at the surface of adjacent cells. Parallel EFF-1 inte...

[ "GOC:bhm", "PMID:24725407" ]

An example of this is eff-1 in C. elegans (G5ECA1) in PMID:24725407 (inferred from direct assay).

[]

[ "GO:0098797" ]

[]

[ "GO:0098797" ]

[]

bhm

2014-06-04T14:45:02Z

false

true

5

GO:1990393

1,990,393

3M complex

cellular_component

A protein complex, at least composed of CUL7, CCDC8 and OBSL1, that is required for maintaining microtubule and genome integrity.

[ "PMID:24793695", "PMID:24793696" ]

null

[]

[ "GO:0032991" ]

[]

[ "GO:0032991" ]

[]

sp

2014-06-05T06:40:49Z

false

true

4

GO:1990394

1,990,394

cellular response to cell wall damage

biological_process

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cell wall damage. The process begins with detection of the damage and ends with a change in state or activity of the cell.

[ "PMID:17287531" ]

null

[]

[ "GO:0051716" ]

[ "has_part GO:0071433" ]

[ "has_part" ]

[ "GO:0071433" ]

[ "GO:0051716", "GO:0071433" ]

[]

al

2014-06-05T16:45:33Z

false

true

9

GO:1990395

1,990,395

meiotic spindle pole body organization

biological_process

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the meiotic spindle pole body.

[ "GOC:vw" ]

null

[]

[ "GO:0051300", "GO:1903046" ]

[ "part_of GO:0000212" ]

[ "part_of" ]

[ "GO:0000212" ]

[ "GO:0000212", "GO:0051300", "GO:1903046" ]

[]

tb

2014-06-06T01:41:05Z

false

true

7

GO:1990396

1,990,396

single-strand break repair via homologous recombination

biological_process

The error-free repair of a single-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchan...

[ "GOC:bhm", "PMID:24339919" ]

null

[]

[ "GO:0000012", "GO:0000725", "GO:0042275" ]

[]

[ "GO:0000012", "GO:0000725", "GO:0042275" ]

[]

bhm

2014-06-09T10:47:04Z

false

true

8

GO:1990397

1,990,397

obsolete queuosine salvage

biological_process

OBSOLETE. Any process which produces queuosine from derivatives of it, without de novo synthesis.

[ "GOC:vw", "PMID:24911101" ]

The reason for obsoletion is that this term was an unnecessary grouping term.

[]

[ "GO:0160254", "GO:0160255" ]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29892\" xsd:anyURI" ]

pr

2014-06-10T14:56:12Z

true

4

GO:1990398

1,990,398

Cus cation efflux complex

cellular_component

Transmembrane complex that mediates resistance to copper and silver by cation efflux directly from the cell using the proton-motive force. Spans the inner membrane, periplasm, and outer membrane. Primarily activated under anaerobic conditions by CusR and CusS but also expressed under extreme copper stress, in aerobic g...

[ "GOC:bhm", "PMID:23122209" ]

An example of this is CusA in E. coli (UniProt symbol P38054) in PMID:23122209.

[ "copper efflux complex", "copper efflux system", "Cus cation efflux system", "silver efflux complex", "silver efflux system" ]

[ "NARROW", "NARROW", "EXACT", "NARROW", "NARROW" ]

[]

[ "GO:0098797", "GO:1903113", "GO:1903114" ]

[]

[ "GO:0098797", "GO:1903113", "GO:1903114" ]

[]

bhm

2014-06-11T08:51:48Z

false

true

6

GO:1990399

1,990,399

epithelium regeneration

biological_process

The regrowth of lost or destroyed epithelium.

[ "GOC:sl", "PMID:19845688" ]

null

[ "regeneration of epithelium" ]

[ "EXACT" ]

[]

[ "GO:0042246", "GO:0060429" ]

[]

[ "GO:0042246", "GO:0060429" ]

[]

sl

2014-06-12T17:14:42Z

false

true

6

GO:1990400

1,990,400

mitochondrial ribosomal large subunit rRNA binding

molecular_function

Binding to a mitochondrial large ribosomal subunit RNA (LSU rRNA).

[ "PMID:24206665" ]

In S. cerevisiae, this is the mitochondrial 21S rRNA

[ "21S rRNA binding", "mitochondrial LSU rRNA binding" ]

[ "NARROW", "EXACT" ]

[]

[ "GO:0070180" ]

[]

[ "GO:0070180" ]

[]

mcc

2014-06-23T16:47:09Z

false

true

7

GO:1990402

1,990,402

embryonic liver development

biological_process

The process occurring during the embryonic phase whose specific outcome is the progression of the liver over time, from its formation to the mature structure.

[ "PMID:15918910" ]

null

[]

[ "GO:0048568" ]

[]

[ "GO:0048568" ]

[]

sl

2014-06-23T20:52:03Z

false

true

1

GO:1990403

1,990,403

embryonic brain development

biological_process

The process occurring during the embryonic phase whose specific outcome is the progression of the brain over time, from its formation to the mature structure.

[ "PMID:15918910" ]

null

[]

[ "GO:0048568" ]

[]

[ "GO:0048568" ]

[]

sl

2014-06-23T20:57:13Z

false

true

9

GO:1990404

1,990,404

NAD+-protein mono-ADP-ribosyltransferase activity

molecular_function

Catalysis of the reaction: amino acyl-[protein] + NAD+ = H+ + (ADP-D-ribosyl)-amino acyl-[protein] + nicotinamide.

[ "PMID:1899243" ]

null

[ "NAD+ ADP-ribosyltransferase activity", "NAD+-protein ADP-ribosyltransferase activity", "protein ADP-ribosylase activity", "protein ADP-ribosyltransferase activity", "protein mono-ADP-ribosyltransferase activity", "ribosylase activity" ]

[ "BROAD", "BROAD", "EXACT", "BROAD", "EXACT", "BROAD" ]

[]

[ "Wikipedia:ADP-ribosylation" ]

[ "GO:0016763", "GO:0140096" ]

[]

[ "GO:0016763", "GO:0140096" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22874\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29560\" xsd:anyURI" ]

pg

2014-06-24T07:04:44Z

false

true

1

GO:1990406

1,990,406

CGRP receptor complex

cellular_component

A transmembrane, G protein-coupled signaling receptor complex recognized by calcitonin gene-related peptides (CGRP).

[ "GOC:bhm", "PMID:20826335" ]

An example of this is CALCRL in human (Q16602) in PMID:20826335 (inferred from direct assay).

[ "calcitonin gene-related polypeptide receptor complex", "Calcitonin-gene-related peptide receptor complex", "CGRP-R complex" ]

[ "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:1903439" ]

[]

[ "GO:1903439" ]

[]

bhm

2014-07-01T14:57:43Z

false

true

5

GO:1990407

1,990,407

calcitonin gene-related peptide binding

molecular_function

Binding to calcitonin gene-related peptide (CGRP).

[ "GOC:bhm", "PMID:10882736" ]

An example of this is CALCRL in human (Q16602) in PMID:10882736 (inferred from direct assay/mutant phenotype/etc.).

[ "calcitonin-gene-related peptide binding", "calcitonin-gene-related polypeptide binding", "CGRP polypeptide binding" ]

[ "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0097644" ]

[]

[ "GO:0097644" ]

[]

bhm

2014-07-02T14:22:06Z

false

true

6

GO:1990408

1,990,408

calcitonin gene-related peptide receptor signaling pathway

biological_process

The series of molecular signals initiated by an extracellular calcitonin gene-related peptide (CGRP) combining with a calcitonin gene-related peptide receptor on the surface of the target cell. Calcitonin gene-related peptide receptors may form dimers, trimers or tetramers.

[ "GOC:bhm", "PMID:10882736" ]

An example of a protein that could be annotated to this term is CALCRL in human (Q16602) in PMID:10882736.

[ "calcitonin-gene-related peptide receptor signaling pathway", "calcitonin-gene-related polypeptide receptor signaling pathway", "CGRP receptor signaling pathway" ]

[ "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0097646" ]

[]

[ "GO:0097646" ]

[]

bhm

2014-07-02T14:32:37Z

false

true

9

GO:1990409

1,990,409

adrenomedullin binding

molecular_function

Binding to adrenomedullin (AM).

[ "GOC:bhm", "PMID:10882736" ]

An example of a protein that could be annotated to this term is CALCRL in human (Q16602) in PMID:10882736.

[ "AM binding" ]

[ "EXACT" ]

[]

[ "GO:0097644" ]

[]

[ "GO:0097644" ]

[]

bhm

2014-07-02T14:37:19Z

false

true

7

GO:1990410

1,990,410

adrenomedullin receptor signaling pathway

biological_process

The series of molecular signals initiated by an extracellular adrenomedullin combining with a dimeric adrenomedullin receptor on the surface of the target cell.

[ "GOC:bhm", "PMID:10882736" ]

An example of a protein that could be annotated to this term is CALCRL in human (Q16602) in PMID:10882736.

[ "AM receptor signaling pathway" ]

[ "EXACT" ]

[]

[ "GO:0097646" ]

[]

[ "GO:0097646" ]

[]

bhm

2014-07-02T14:43:31Z

false

true

7

GO:1990411

1,990,411

hercynylcysteine sulfoxide lyase activity (ergothioneine-forming)

molecular_function

Catalysis of the reaction: hercynylcysteine sulfoxide + 2H+ = ergothioneine + pyruvate + ammonium.

[ "PMID:24828577" ]

null

[]

[ "MetaCyc:RXN-14428", "RHEA:42688" ]

[ "GO:0016846" ]

[ "part_of GO:0052699" ]

[ "part_of" ]

[ "GO:0052699" ]

[ "GO:0016846", "GO:0052699" ]

[]

[ "skos:exactMatch RHEA:42688", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]

mah

2014-07-02T15:45:43Z

false

true

3

GO:1990412

1,990,412

obsolete hercynylselenocysteine lyase activity (selenoneine-forming)

molecular_function

OBSOLETE. Catalysis of the reaction: hercynylselenocysteine + 2H+ = selenoneine + pyruvate + ammonium.

[ "PMID:24828577" ]

This term was obsoleted based on PMID:36071162 that has demonstrated that this reaction does not take place.

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26907\" xsd:anyURI" ]

mah

2014-07-02T15:51:07Z

true

5

GO:1990413

1,990,413

eyespot apparatus

cellular_component

A small pigmented organelle used in single-celled organisms to detect light.

[ "Wikipedia:Eyespot_apparatus" ]

null

[ "eyespot", "stigma" ]

[ "RELATED", "RELATED" ]

[]

[ "GO:0043231" ]

[]

[ "GO:0043231" ]

[]

cjm

2014-07-03T21:26:24Z

false

true

4

GO:1990414

1,990,414

replication-born double-strand break repair via sister chromatid exchange

biological_process

The repair of a replication-born double-strand DNA break in which the DNA molecule is repaired using the homologous sequence of the sister chromatid which serves as a template to repair the breaks.

[ "GOC:rb", "PMID:12820977", "PMID:16888651" ]

null

[ "replication-born DSB repair by SCE" ]

[ "EXACT" ]

[]

[ "GO:0000724" ]

[]

[ "GO:0000724" ]

[]

rb

2014-07-10T21:20:34Z

false

true

8

GO:1990417

1,990,417

snoRNA release from pre-rRNA

biological_process

The release of snoRNA from pre-rRNA.

[ "GOC:rb", "PMID:16908538" ]

An example of this process is yeast HAS1 from PMID:16908538, inferred from mutant phenotype assay.

[]

[ "GO:0006364" ]

[]

[ "GO:0006364" ]

[]

rb

2014-07-11T21:43:27Z

false

true

9

GO:1990418

1,990,418

response to insulin-like growth factor stimulus

biological_process

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin-like growth factor stimulus.

[ "PMID:21932665" ]

null

[]

[ "GO:0009725" ]

[]

[ "GO:0009725" ]

[]

sl

2014-07-14T22:47:59Z

false

true

3

GO:1990419

1,990,419

obsolete response to elemental metal

biological_process

OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an elemental metal stimulus.

[ "PMID:22688007" ]

This term was obsoleted at the TermGenie Gatekeeper stage.

[ "response to elemental metal" ]

[ "EXACT" ]

[]

sl

2014-07-15T20:17:56Z

true

2

GO:1990420

1,990,420

obsolete establishment of septation initiation network asymmetry

biological_process

OBSOLETE. The septation initiation signaling process by which the activity of the septation initiation network (SIN) is activated asymmetrically on the spindle pole bodies.

[ "PMID:22786806" ]

The reason for obsoletion is that this term is pre-composed and should be represented as a GO-CAM model.

[ "establishment of SIN asymmetry" ]

[ "EXACT" ]

[]

[ "GO:0031028" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30125\" xsd:anyURI" ]

al

2014-07-16T13:51:36Z

true

7

GO:1990423

1,990,423

RZZ complex

cellular_component

A kinetochore component required for both meiotic and mitotic spindle assembly checkpoints.

[ "PMID:12686595", "PMID:15922598", "PMID:20462495" ]

Example annotations for this term would be D. melanogaster mit(1)15 (Q9W4X9), rod and zwilch (Q9VA00).

[ "Rod-Zwilch-Zw10 complex" ]

[ "EXACT" ]

[]

[ "GO:0032991" ]

[ "part_of GO:0000776" ]

[ "part_of" ]

[ "GO:0000776" ]

[ "GO:0000776", "GO:0032991" ]

[]

jl

2014-07-23T11:16:42Z

false

true

3

GO:1990424

1,990,424

protein arginine kinase activity

molecular_function

Catalysis of the reaction: ATP + a protein arginine = ADP + protein arginine phosphate.

[ "PMID:22517742", "RHEA:43384" ]

This reaction occurs in bacterial species e.g. Bacillus subtilis.

[ "protein-arginine kinase activity" ]

[ "EXACT" ]

[]

[ "EC:2.7.14.1", "RHEA:43384" ]

[ "GO:0004672" ]

[]

[ "GO:0004672" ]

[]

[ "skos:exactMatch EC:2.7.14.1", "skos:exactMatch RHEA:43384", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]

jl

2014-07-23T13:35:56Z

false

true

4

GO:1990425

1,990,425

ryanodine receptor complex

cellular_component

A voltage-gated calcium-release channel complex of the sarcoplasmic or endoplasmic reticulum. It plays an important role in the excitation-contraction (E-C) coupling of muscle cells. RyR comprises a family of ryanodine receptors, widely expressed throughout the animal kingdom.

[ "GOC:ame", "PMID:22822064" ]

An example of this is RyR1 in rabbit (P11716) in PMID:2550460 (inferred from electron microscopy).

[ "RyR" ]

[ "RELATED" ]

[]

[ "GO:0005891", "GO:0140534" ]

[ "part_of GO:0033017" ]

[ "part_of" ]

[ "GO:0033017" ]

[ "GO:0005891", "GO:0033017", "GO:0140534" ]

[]

anm

2014-07-24T09:36:41Z

false

true

8

GO:1990426

1,990,426

mitotic recombination-dependent replication fork processing

biological_process

Replication fork processing that includes recombination between DNA near the arrested fork and homologous sequences. Proteins involved in homologous recombination are required for replication restart.

[ "GOC:mah", "PMID:23093942" ]

null

[ "homologous recombination dependent replication fork recovery", "homologous recombination-dependent replication fork processing", "mitotic recombination involved in collapsed replication fork processing", "mitotic recombination involved in recovery from replication fork arrest", "mitotic recombination invol...

[ "RELATED", "EXACT", "EXACT", "EXACT", "EXACT", "RELATED", "RELATED", "RELATED" ]

[ "GO:1903211" ]

[]

[ "GO:0031297", "GO:1990505" ]

[ "has_part GO:0006312" ]

[ "has_part" ]

[ "GO:0006312" ]

[ "GO:0006312", "GO:0031297", "GO:1990505" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22928\" xsd:anyURI" ]

mah

2014-07-24T09:42:54Z

false

true

3

GO:1990427

1,990,427

stereocilia tip-link density

cellular_component

An electron-dense plaque at either end of a stereocilia tip link that provides the anchor in the stereocilia membrane.

[ "PMID:19447093", "PMID:21709241" ]

null

[]

[ "GO:0110165" ]

[ "part_of GO:0002140", "part_of GO:0042995" ]

[ "part_of", "part_of" ]

[ "GO:0002140", "GO:0042995" ]

[ "GO:0002140", "GO:0042995", "GO:0110165" ]

[]

sl

2014-07-25T20:55:36Z

false

true

8

GO:1990428

1,990,428

miRNA transport

biological_process

The directed movement of microRNA (miRNA) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore.

[ "GO:jl", "PMID:24356509" ]

null

[ "microRNA transport" ]

[ "EXACT" ]

[]

[ "GO:0050658" ]

[]

[ "GO:0050658" ]

[]

jl

2014-07-29T14:03:46Z

false

true

6

GO:1990429

1,990,429

peroxisomal importomer complex

cellular_component

A protein complex responsible for transporting proteins into the peroxisomal matrix. An example of this complex is Pex14 found in S. cerevisae which has 9 core components and 12 transient interaction partners.

[ "PMID:12667447", "PMID:20154681", "PMID:22375831" ]

null

[ "peroxisomal import pore", "peroxisomal protein import machinery", "Pex14 complex", "Pex17p-Pex14p docking complex" ]

[ "EXACT", "EXACT", "NARROW", "RELATED" ]

[ "GO:1990415" ]

[]

[ "GO:1990351" ]

[]

[ "GO:1990351" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22100\" xsd:anyURI" ]

jl

2014-07-29T14:45:28Z

false

true

9

GO:1990430

1,990,430

extracellular matrix protein binding

molecular_function

Binding to a protein that is part of an extracellular matrix.

[ "PMID:22355679" ]

null

[]

[ "GO:0005515" ]

[]

[ "GO:0005515" ]

[]

jl

2014-07-29T14:57:07Z

false

true

2

GO:1990431

1,990,431

priRNA 3'-end processing

biological_process

The process of forming the mature 3' end of a priRNA molecule.

[ "PMID:24095277" ]

null

[ "primal small RNA 3'-end processing", "priRNA 3' end processing" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0043628" ]

[]

[ "GO:0043628" ]

[]

jl

2014-07-29T15:34:19Z

false

true

6

GO:1990432

1,990,432

siRNA 3'-end processing

biological_process

The process of forming the mature 3' end of a siRNA molecule.

[ "PMID:24095277" ]

null

[ "siRNA 3' end processing", "small interfering RNA 3'-end processing" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0043628" ]

[]

[ "GO:0043628" ]

[]

jl

2014-07-29T15:38:38Z

false

true

5

GO:1990434

1,990,434

lower tip-link density

cellular_component

An electron-dense plaque at the lower end of a stereocilia tip link that provides the anchor in the stereocilia membrane at the tip of the stereocilium from which the tip link rises.

[ "PMID:19447093" ]

null

[ "LTLD" ]

[ "EXACT" ]

[]

[ "GO:1990427" ]

[]

[ "GO:1990427" ]

[]

sl

2014-07-30T16:34:34Z

false

true

4

GO:1990435

1,990,435

upper tip-link density

cellular_component

An electron-dense plaque at the upper end of a stereocilia tip link that provides the anchor in the stereocilia membrane on the side of the stereocilium where the tip link ends.

[ "PMID:19447093" ]

null

[ "UTLD" ]

[ "EXACT" ]

[]

[ "GO:1990427" ]

[]

[ "GO:1990427" ]

[]

sl

2014-07-30T16:36:32Z

false

true

7

GO:1990436

1,990,436

obsolete MAPK cascade involved in oxidative stress signaling pathway

biological_process

OBSOLETE. The series of molecular signals in which a MAP kinase cascade activated by oxidative stress relays one or more of the signals, MAP kinase cascades involve at least three protein kinase activities and culminate in the phosphorylation and activation of a MAP kinase. Just FYI in pombe the osmotic stress and oxid...

[ "PMID:10398679" ]

This term was obsoleted at the TermGenie Gatekeeper stage.

[ "MAPK cascade involved in oxidative stress signaling pathway" ]

[ "EXACT" ]

[]

al

2014-07-31T10:10:38Z

true

4

GO:1990437

1,990,437

snRNA 2'-O-methylation

biological_process

The posttranscriptional addition of a methyl group to the 2' oxygen atom of a nucleotide residue in an snRNA molecule.

[ "PMID:11842100", "PMID:9844635" ]

null

[]

[ "GO:0106349" ]

[]

[ "GO:0106349" ]

[]

mah

2014-07-31T11:58:18Z

false

true

1

GO:1990438

1,990,438

U6 2'-O-snRNA methylation

biological_process

The posttranscriptional addition a methyl group to the 2'-oxygen atom of a nucleotide residue in an U6 snRNA molecule.

[ "PMID:11842100", "PMID:9844635" ]

null

[]

[ "GO:1990437" ]

[]

[ "GO:1990437" ]

[]

mah

2014-07-31T12:04:21Z

false

true

7

GO:1990439

1,990,439

MAP kinase serine/threonine phosphatase activity

molecular_function

Catalysis of the reaction: MAP kinase threonine phosphate + H2O = MAP kinase threonine + phosphate and MAP kinase serine phosphate + H2O = MAP kinase serine + phosphate.

[ "PMID:10398679" ]

null

[]

[ "GO:0004722", "GO:0033549" ]

[]

[ "GO:0004722", "GO:0033549" ]

[]

[ "skos:broadMatch EC:3.1.3.16", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI" ]

al

2014-07-31T12:21:04Z

false

true

2

GO:1990440

1,990,440

obsolete positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress

biological_process

OBSOLETE. Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an endoplasmic reticulum stress.

[ "GOC:bf", "GOC:PARL", "PMID:21113145" ]

This term was obsoleted because it represents a GO-CAM model.

[ "activation of transcription from RNA polymerase II promoter in response to ER stress", "ER stress-induced upregulation of transcription", "stimulation of transcription from RNA polymerase II promoter in response to ER stress", "up-regulation of transcription from RNA polymerase II promoter in response to end...

[ "EXACT", "BROAD", "EXACT", "EXACT", "BROAD", "EXACT", "EXACT" ]

[]

[ "GO:0034976", "GO:0045944" ]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26004\" xsd:anyURI" ]

bf

2014-07-31T12:56:54Z

true

4

GO:1990441

1,990,441

obsolete negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress

biological_process

OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an endoplasmic reticulum stress.

[ "GOC:bf", "GOC:PARL", "PMID:21113145" ]

This term was obsoleted because it represents a GO-CAM model.

[ "down regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress", "down-regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress", "ER stress-induced negative regulation of transcription from RNA polymerase II promoter"...

[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0000122", "GO:0034976" ]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26004\" xsd:anyURI" ]

bf

2014-07-31T13:08:54Z

true

4

GO:1990442

1,990,442

intrinsic apoptotic signaling pathway in response to nitrosative stress

biological_process

The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to nitrosative stress; a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced follo...

[ "GOC:bf", "GOC:PARL", "PMID:23985028" ]

null

[ "nitrosative stress-induced apoptosis", "nitrosative stress-induced intrinsic apoptotic signaling pathway" ]

[ "RELATED", "EXACT" ]

[]

[ "GO:0071500", "GO:0097193" ]

[]

[ "GO:0071500", "GO:0097193" ]

[]

bf

2014-07-31T14:28:16Z

false

true

8

GO:1990443

1,990,443

peptidyl-threonine autophosphorylation

biological_process

The phosphorylation by a protein of one or more of its own threonine amino acid residues, or a threonine residue on an identical protein.

[ "PMID:7803855" ]

null

[]

[ "gocheck_obsoletion_candidate" ]

[]

[ "GO:0018107", "GO:0046777" ]

[]

[ "GO:0018107", "GO:0046777" ]

[]

al

2014-08-02T15:08:41Z

false

true

2

GO:1990444

1,990,444

F-box domain binding

molecular_function

Binding to an F-box domain of a protein.

[ "GOC:bf", "GOC:PARL", "InterPro:IPR001810", "PMID:12628165" ]

null

[]

[ "GO:0019904" ]

[]

[ "GO:0019904" ]

[]

bf

2014-08-05T13:45:14Z

false

true

2

GO:1990445

1,990,445

obsolete Multiciliate cell differentiation

biological_process

OBSOLETE. The process in which a relatively unspecialized cell acquires features of a multiciliated cell, a specialized epithelial cell type that extends anywhere from 150 to 200 motile cilia per cell in order to produce a vigorous fluid flow critical to human health in several organ systems.

[ "PMID:22231168", "PMID:24934224" ]

This term was obsoleted at the TermGenie Gatekeeper stage.

[ "Multiciliate cell differentiation" ]

[ "EXACT" ]

[]

sp

2014-08-05T14:31:28Z

true

5

GO:1990446

1,990,446

U1 snRNP binding

molecular_function

Binding to a U1 small nuclear ribonucleoprotein particle.

[ "PMID:14713954" ]

null

[]

[ "GO:0070990" ]

[]

[ "GO:0070990" ]

[]

mah

2014-08-06T09:29:44Z

false

true

2

GO:1990448

1,990,448

exon-exon junction complex binding

molecular_function

Binding to an exon-exon junction complex, a protein complex deposited by the spliceosome upstream of messenger RNA exon-exon junctions. The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay.

[ "GOC:sart", "PMID:24967911" ]

null

[ "EJC binding" ]

[ "EXACT" ]

[]

[ "GO:0044877" ]

[]

[ "GO:0044877" ]

[]

sart

2014-08-06T10:02:46Z

false

true

7

GO:1990449

1,990,449

obsolete amylin receptor

cellular_component

OBSOLETE. A G protein-coupled signalling receptor complex consisting of the calcitonin receptor and a receptor activity-modifying protein (RAMP). Amylin is produced in beta-islet cells of the pancreas. It is implicated in selective inhibition of insulin-stimulated glucose utilization and glycogen deposition in muscle, ...

[ "GOC:bhm", "PMID:10871269" ]

An example of this is CALCR in human (P30988) in PMID:10871269.

[ "AMY1 receptor", "AMY2 receptor", "AMY3 receptor", "amylin receptor", "CALCR-RAMP1 receptor", "CALCR-RAMP2 receptor", "CALCR-RAMP3 receptor" ]

[ "NARROW", "NARROW", "NARROW", "EXACT", "NARROW", "NARROW", "NARROW" ]

[]

bhm

2014-08-06T10:21:37Z

true

5

GO:1990450

1,990,450

linear polyubiquitin binding

molecular_function

Binding to a linear polymer of ubiquitin. Linear ubiquitin polymers are formed by linking the amino-terminal methionine (M1) of one ubiquitin molecule to the carboxy-terminal glycine (G76) of the next.

[ "GOC:bf", "GOC:PARL", "PMID:23453807" ]

null

[ "M1-linked ubiquitin chain binding" ]

[ "EXACT" ]

[]

[ "GO:0043130" ]

[]

[ "GO:0043130" ]

[]

bf

2014-08-06T11:10:26Z

false

true

4

GO:1990451

1,990,451

cellular stress response to acidic pH

biological_process

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in the homeostasis of organismal or cellular pH (with pH < 7). pH is a measure of the acidity or basicity of an aqueous solution.

[ "GOC:BHF", "GOC:curators", "GOC:rl", "PMID:10615049" ]

An example of this is NOX1 in human (Q9Y5S8) in PMID:10615049.

[ "cellular stress response to acidity" ]

[ "BROAD" ]

[]

[ "GO:0062197", "GO:0071468" ]

[]

[ "GO:0062197", "GO:0071468" ]

[]

jl

2014-08-06T14:06:58Z

false

true

5

GO:1990452

1,990,452

Parkin-FBXW7-Cul1 ubiquitin ligase complex

cellular_component

A ubiquitin ligase complex containing Parkin (PARK2), the F-box protein FBXW7 (also called SEL-10) and a cullin from the Cul1 subfamily; substrate specificity is conferred by the F-box protein.

[ "GOC:bf", "GOC:PARL", "PMID:12628165" ]

null

[ "Park2-FBXW7-Cul1 complex", "Parkin-FBXW7-Cul1 protein complex", "Parkin-HSel-10-Cullin-1 complex", "Parkin/Cul1/F-box protein complex", "PRKN-FBXW7-Cul1 complex" ]

[ "EXACT", "EXACT", "NARROW", "EXACT", "EXACT" ]

[]

[ "GO:0000151" ]

[]

[ "GO:0000151" ]

[]

bf

2014-08-07T14:25:49Z

false

true

4

GO:1990453

1,990,453

TINTIN complex

cellular_component

A protein complex involved in the disassembly and subsequent reassembly of nucleosomes. It associates with the coding region of transcriptionally active genes where it interacts with the RNA polymerase II and affects its processivity during co-transcriptional RNA processing and maturation. It exists as a functionally i...

[ "GOC:bhm", "PMID:24843044", "PMID:36190236" ]

null

[ "eaf5/7/3 complex", "nucleosome disassembly/reassembly complex" ]

[ "EXACT", "BROAD" ]

[]

[ "GO:0140513" ]

[]

[ "GO:0140513" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31211\" xsd:anyURI" ]

bhm

2014-08-08T15:18:30Z

false

true

1

GO:1990454

1,990,454

L-type voltage-gated calcium channel complex

cellular_component

A type of voltage-dependent calcium channel responsible for excitation-contraction coupling of skeletal, smooth, and cardiac muscle. 'L' stands for 'long-lasting' referring to the length of activation.

[ "GOC:ame", "PMID:12946355" ]

Examples of this are CACNA1S, CACNA2D1, CACNB1, CACNG1 in rabbit (UniProt symbol P07293, P13806, P19517 and P19518) in PMID:12946355 (inferred from direct assay).

[ "cardiac muscle L-type voltage-gated calcium channel complex", "skeletal muscle L-type voltage-gated calcium channel complex" ]

[ "NARROW", "NARROW" ]

[]

[ "GO:0005891" ]

[ "part_of GO:0030315" ]

[ "part_of" ]

[ "GO:0030315" ]

[ "GO:0005891", "GO:0030315" ]

[]

anm

2014-08-12T17:22:10Z

false

true

6

GO:1990455

1,990,455

PTEN phosphatase complex

cellular_component

A phospholipid phosphatase complex that catalyses the hydrolysis of the second messenger PtdIns (3,4,5)P3. Will also dephosphorylate PtdIns(3,4)P2, PtdIns3P, and Ins(1,3,4,5)P4. Dimerization is critical for its lipid phosphatase function.

[ "GOC:bhm", "PMID:24766807" ]

An example of this is PTEN in human (P60484) in PMID:24766807 (inferred from direct assay).

[ "phosphatase and tensin homolog", "phosphatase and tensin homolog deleted on chromosome ten homodimer", "phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN homodimer" ]

[ "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:1904144" ]

[]

[ "GO:1904144" ]

[]

bhm

2014-08-13T10:21:20Z

false

true

7

GO:1990458

1,990,458

lipooligosaccharide binding

molecular_function

Binding to lipooligosaccharide. Lipooligosaccharides (LOSs) are the major glycolipids expressed on mucosal Gram-negative bacteria.

[ "GOC:hjd", "PMID:8894399" ]

ChEBI distinguishes an oligosaccharide from a polysaccharide as the latter being anything of length 10 or greater.

[ "endotoxin binding", "LOS binding" ]

[ "RELATED", "RELATED" ]

[]

[ "GO:0097367" ]

[]

[ "GO:0097367" ]

[]

hjd

2014-08-15T19:58:08Z

false

true

9

GO:1990459

1,990,459

transferrin receptor binding

molecular_function

Binding to a transferrin receptor.

[ "GOC:pm", "PMID:9819414" ]

null

[]

[ "GO:0005102" ]

[]

[ "GO:0005102" ]

[]

tb

2014-08-18T20:14:24Z

false

true

4

GO:1990460

1,990,460

leptin receptor binding

molecular_function

Binding to a leptin receptor.

[ "GOC:pm", "PMID:22405007" ]

null

[]

[ "GO:0005102" ]

[]

[ "GO:0005102" ]

[]

tb

2014-08-18T20:17:43Z

false

true

6

GO:1990461

1,990,461

detoxification of iron ion

biological_process

Any process that reduces or removes the toxicity of iron ion. These include transport of iron away from sensitive areas and to compartments or complexes whose purpose is sequestration of iron ion.

[ "GOC:sart", "PMID:23064556" ]

null

[]

[ "GO:0061687" ]

[ "part_of GO:0010039" ]

[ "part_of" ]

[ "GO:0010039" ]

[ "GO:0010039", "GO:0061687" ]

[]

sart

2014-08-19T10:12:46Z

false

true

6

GO:1990462

1,990,462

omegasome

cellular_component

Omega-shaped (as in the Greek capital letter) intracellular membrane-bounded organelle enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum. Omegasomes are the first step of the formation of autophagosomes via the phagophore assembly sites.

[ "GOC:autophagy", "GOC:mf", "PMID:18725538", "PMID:24591649" ]

null

[]

[ "GO:0043231" ]

[ "part_of GO:0012505" ]

[ "part_of" ]

[ "GO:0012505" ]

[ "GO:0012505", "GO:0043231" ]

[]

pr

2014-08-19T12:26:40Z

false

true

9

GO:1990463

1,990,463

lateral cortical node

cellular_component

A protein complex that is anchored at the cortical face of the plasma membrane, and contains proteins involved in regulating cell cycle progression. In Schizosaccharomyces pombe, lateral cortical nodes are several megadaltons in size, and contain Slf1, which anchors the complex at the membrane, and the methyltransferas...

[ "GOC:mah", "PMID:25009287" ]

null

[ "Skb1-containing cortical node" ]

[ "EXACT" ]

[]

[ "GO:0032991" ]

[ "part_of GO:0097575" ]

[ "part_of" ]

[ "GO:0097575" ]

[ "GO:0032991", "GO:0097575" ]

[]

pr

2014-08-20T09:04:45Z

false

true

3

GO:1990464

1,990,464

(2R)-hydroxyacid dehydrogenase (quinone) activity

molecular_function

Catalysis of the reaction: a (2R)-2-hydroxycarboxylate + a quinone = a 2-oxocarboxylate + a quinol.

[ "PMID:3013300", "PMID:4582730", "RHEA:11272" ]

(R)-lactate, (R)-malate and meso-tartrate are good substrates. Ubiquinone-1 and the dye 2,6-dichloroindophenol can act as acceptors; NAD+ and NADP+ are not acceptors.

[ "(R)-2-hydroxy acid dehydrogenase activity", "(R)-2-hydroxy-acid:(acceptor) 2-oxidoreductase activity", "(R)-2-hydroxyacid:quinone oxidoreductase activity", "D-2-hydroxyacid dehydrogenase (quinone) activity", "D-lactate dehydrogenase (quinone) activity", "D-lactate dehydrogenase activity", "D-lactate:qu...

[ "RELATED", "RELATED", "RELATED", "EXACT", "RELATED", "RELATED", "RELATED" ]

[]

[ "EC:1.1.5.10", "MetaCyc:RXN-14931", "RHEA:11272" ]

[ "GO:0016901", "GO:0033719" ]

[]

[ "GO:0016901", "GO:0033719" ]

[]

[ "skos:exactMatch EC:1.1.5.10", "skos:exactMatch MetaCyc:RXN-14931", "skos:exactMatch RHEA:11272", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28324\" xsd:anyURI" ]

pr

2014-08-22T10:13:42Z

false

true

7

GO:1990465

1,990,465

obsolete aldehyde oxygenase (deformylating) activity

molecular_function

OBSOLETE. Catalysis of the reaction a long-chain aldehyde + O2 + 2 NADPH = an alkane + formate + H2O + 2 NADP+.

[ "GOC:mengo_curators", "PMID:22947199" ]

This term was obsoleted because it represents the same reaction as aldehyde decarbonylase activity ; GO:0071771.

[]

[ "GO:0071771" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25056\" xsd:anyURI" ]

tt

2014-08-25T15:16:43Z

true

1

GO:1990466

1,990,466

protein autosumoylation

biological_process

The sumoylation by a protein of one or more of its own amino acid residues, or residues on an identical protein.

[ "PMID:21518767", "PMID:23443663" ]

null

[ "protein auto-sumoylation", "protein self-sumoylation" ]

[ "EXACT", "EXACT" ]

[]

[ "gocheck_do_not_annotate" ]

[]

[ "GO:0016925" ]

[]

[ "GO:0016925" ]

[]

se

2014-08-25T22:37:21Z

false

true

4

GO:1990467

1,990,467

NuA3a histone acetyltransferase complex

cellular_component

A NuA3 complex that catalyzes the acetylation of Histone H3. In S. cerevisiae, this complex consists of Eaf6p, Nto1p, Sas3p, Taf14p, Yng1p and associates with H3K4me3 using Yng1p.

[ "GOC:rb", "PMID:25104842" ]

null

[]

[ "GO:0033100" ]

[]

[ "GO:0033100" ]

[]

rb

2014-08-25T23:07:45Z

false

true

1

GO:1990468

1,990,468

NuA3b histone acetyltransferase complex

cellular_component

A NuA3 complex that catalyzes the acetylation of Histone H3. In S. cerevisiae, this complex consists of Eaf6p, Nto1p, Sas3p, Taf14p, Pdp3 and associates with H3K4me3 via Pdp3p.

[ "GOC:rb", "PMID:25104842" ]

null

[]

[ "GO:0033100" ]

[]

[ "GO:0033100" ]

[]

rb

2014-08-25T23:13:37Z

false

true

4

GO:1990469

1,990,469

Rhino-Deadlock-Cutoff Complex

cellular_component

Protein complex found in Drosophila consisting of the gene products of cuff, del and rhi. It regulates the licensing of transcription of dual-strand PIWI interacting RNA (piRNA) source loci by binding to dual-strand-cluster chromatin, probably via the H3K9me3-binding activity of Rhi. Rhi binding brings the putative ter...

[ "GOC:bhm", "PMID:24906153" ]

An example of this is cuff in Drosophila melanogaster (Q9V629) in PMID:24906153.

[ "RDC complex", "rhi-del-cuff complex" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0140513", "GO:1990923" ]

[ "part_of GO:0043073" ]

[ "part_of" ]

[ "GO:0043073" ]

[ "GO:0043073", "GO:0140513", "GO:1990923" ]

[]

bhm

2014-08-29T14:08:37Z

false

true

9

GO:1990470

1,990,470

piRNA cluster binding

molecular_function

Binding to piRNA clusters, double-stranded DNA regions that give rise to PIWI-interacting RNAs (piRNAs).

[ "GOC:bhm", "PMID:24906153" ]

An example of this is rhi in Drosophila melanogaster (Q7JXA8) in PMID:24906153 (inferred from direct assay).

[]

[ "GO:1990837" ]

[]

[ "GO:1990837" ]

[]

bhm

2014-08-29T14:23:38Z

false

true

6

GO:1990472

1,990,472

piRNA dual-strand cluster binding

molecular_function

Binding to dual-strand piRNA clusters, double-stranded DNA regions that give rise to PIWI-interacting RNAs (piRNAs) where piRNAs originate from both DNA strands via noncanonical transcription.

[ "GOC:bhm", "PMID:24906153" ]

An example of this is rhi in Drosophila melanogaster (Q7JXA8) in PMID:24906153 (inferred from direct assay).

[]

[ "GO:1990470" ]

[]

[ "GO:1990470" ]

[]

bhm

2014-08-29T14:50:54Z

false

true

7

GO:1990473

1,990,473

ciliary targeting signal binding

molecular_function

Binding to a ciliary targeting sequence, a specific peptide sequence that acts as a signal to localize a membrane protein to the ciliary membrane.

[ "GOC:krc", "PMID:18256283", "PMID:19575670", "PMID:20603001", "PMID:20697559" ]

null

[ "CTS binding" ]

[ "EXACT" ]

[]

[ "GO:0005048" ]

[]

[ "GO:0005048" ]

[]

pr

2014-09-02T08:22:03Z

false

true

4

GO:1990474

1,990,474

synaptic vesicle, readily releasable pool

cellular_component

A synaptic vesicle belonging to the pool of vesicles that are the first to be released as a result of chemical or electrical stimulation e.g. by an action potential, have the highest presynaptic membrane fusion probability and correspond to about 1% of the total number of synaptic vesicles at a resting terminal bouton.

[ "GOC:pad", "PMID:22745285" ]

null

[ "readily releasable pool of synaptic vesicles", "RRP" ]

[ "EXACT", "RELATED" ]

[]

[ "GO:0008021" ]

[ "part_of GO:0043195" ]

[ "part_of" ]

[ "GO:0043195" ]

[ "GO:0008021", "GO:0043195" ]

[]

pr

2014-09-02T09:02:41Z

false

true

7

GO:1990476

1,990,476

synaptic vesicle, resting pool

cellular_component

A synaptic vesicle belonging to the pool that remain unreleased even after prolonged stimulation causes a saturating degree of vesicular turnover. 50-80% of the total number of synaptic vesicles at a resting terminal bouton are in this pool.

[ "GOC:pad", "PMID:22745285" ]

null

[ "reserve pool of synaptic vesicles", "resting pool of synaptic vesicles" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0008021" ]

[ "part_of GO:0043195" ]

[ "part_of" ]

[ "GO:0043195" ]

[ "GO:0008021", "GO:0043195" ]

[]

pr

2014-09-02T09:12:37Z

false

true

6

GO:1990477

1,990,477

MTREC complex

cellular_component

Protein complex formed by an RNA binding protein Red1, an RNA helicase Mtl1, Red5, Rmn1, Iss10/Pir1, and Ars2/Pir2. This complex is required for the recruitment of the nuclear exosome to Mmi1 nuclear focus. It is likely related to the human CBCN complex. This complex is also known as RNA silencing (NURS) complex.

[ "PMID:24210919", "PMID:24713849", "PMID:32012158" ]

null

[ "Mtl1-Red1 core complex", "NURS complex", "PAXT complex" ]

[ "EXACT", "EXACT", "EXACT" ]

[ "GO:1990345" ]

[]

[ "GO:0140513" ]

[]

[ "GO:0140513" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19059\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21207\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26055\" xsd:anyURI" ]

mah

2014-03-24T13:30:52Z

false

true

6

GO:1990478

1,990,478

response to ultrasound

biological_process

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultrasonic stimulus.

[ "PMID:20950932" ]

null

[]

[ "GO:0009612" ]

[]

[ "GO:0009612" ]

[]

sl

2014-09-09T22:11:32Z

false

true

9

GO:1990480

1,990,480

obsolete geranyl diphosphate synthase

molecular_function

OBSOLETE. Catalyzes the condensation of dimethylallyl diphosphate and isopentenyl diphosphate to geranyl diphosphate, the key precursor of monoterpene biosynthesis.

[ "GOC:mengo_curators", "PMID:10557273" ]

This term was obsoleted at the TermGenie Gatekeeper stage.

[]

[ "GO:0004161" ]

[]

tt

2014-09-10T01:14:17Z

true

6

GO:1990481

1,990,481

mRNA pseudouridine synthesis

biological_process

The intramolecular conversion of uridine to pseudouridine in an mRNA molecule.

[ "PMID:25192136" ]

null

[ "mRNA pseudouridylation" ]

[ "EXACT" ]

[]

[ "GO:0001522", "GO:0016556" ]

[]

[ "GO:0001522", "GO:0016556" ]

[]

mcc

2014-09-12T15:13:39Z

false

true

8

GO:1990482

1,990,482

sphingolipid alpha-glucuronosyltransferase activity

molecular_function

Catalysis of the reaction: UDP-glucuronate + inositol phosphorylceramide (IPC) = UDP + GlcA-IPC.

[ "GOC:tb", "PMID:25122154" ]

null

[ "inositol phosphorylceramide glucuronosyltransferase activity" ]

[ "RELATED" ]

[]

[ "GO:0008194" ]

[]

[ "GO:0008194" ]

[]

tb

2014-09-12T22:10:09Z

false

true

1

GO:1990483

1,990,483

obsolete Clr6 histone deacetylase complex I''

cellular_component

OBSOLETE. A histone deacetylase complex involved in chromatin organization. In Schizosaccharomyces pombe this complex consists of Clr6, Nts1, Mug165, and Png3.

[ "PMID:25002536" ]

The reason for obsoletion is that there is no evidence that this function/process/component exists.

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27509\" xsd:anyURI" ]

al

2014-09-16T10:40:51Z

true

8

GO:1990484

1,990,484

aerobic lactate catabolic process

biological_process

The chemical reactions and pathways resulting in the breakdown of lactate (2-hydroxypropanoic acid) in the presence of oxygen.

[ "GOC:mengo_curators", "PMID:8941775" ]

null

[ "aerobic lactic acid catabolic process" ]

[ "RELATED" ]

[]

[ "GO:1903457" ]

[]

[ "GO:1903457" ]

[]

tt

2014-09-20T05:42:51Z

false

true

3

GO:1990485

1,990,485

anaerobic lactate catabolic process

biological_process

The chemical reactions and pathways resulting in the breakdown of lactate (2-hydroxypropanoic acid) in the absence of oxygen.

[ "GOC:mengo_curators", "PMID:11133436" ]

null

[ "anaerobic lactic acid catabolic process" ]

[ "RELATED" ]

[]

[ "GO:1903457" ]

[]

[ "GO:1903457" ]

[]

tt

2014-09-20T16:48:06Z

false

true

1

GO:1990486

1,990,486

anaerobic fatty acid catabolic process

biological_process

The chemical reactions and pathways resulting in the breakdown of a fatty acid in the absence of oxygen. A fatty acid is any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which...

[ "GOC:mengo_curators", "PMID:17329794" ]

null

[ "anaerobic fatty acid degradation" ]

[ "EXACT" ]

[]

[ "GO:0009062" ]

[]

[ "GO:0009062" ]

[]

tt

2014-09-20T17:25:48Z

false

true

6

GO:1990487

1,990,487

anaerobic lignin catabolic process

biological_process

The chemical reactions and pathways resulting in the breakdown of lignin in the absence of oxygen. Lignin is a class of polymers of phenylpropanoid units.

[ "DOI:10.1039/C3EE40932E", "GOC:mengo_curators" ]

null

[ "anaerobic lignin degradation" ]

[ "EXACT" ]

[]

[ "GO:0046274" ]

[]

[ "GO:0046274" ]

[]

tt

2014-09-20T17:35:09Z

false

true

3

GO:1990488

1,990,488

anaerobic cellulose catabolic process

biological_process

The chemical reactions and pathways resulting in the breakdown of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, in absence of oxygen.

[ "GOC:mengo_curators", "PMID:8561466" ]

null

[ "anaerobic cellulose degradation" ]

[ "EXACT" ]

[]

[ "GO:0030245" ]

[]

[ "GO:0030245" ]

[]

tt

2014-09-20T17:43:59Z

false

true

5

GO:1990489

1,990,489

anaerobic pectin catabolic process

biological_process

The chemical reactions and pathways resulting in the breakdown of pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues, in the absence of oxygen.

[ "GOC:mengo_curators", "PMID:23079077" ]

null

[ "anaerobic pectin degradation" ]

[ "EXACT" ]

[]

[ "GO:0045490" ]

[]

[ "GO:0045490" ]

[]

tt

2014-09-20T18:09:53Z

false

true

7

GO:1990490

1,990,490

archaeal proton-transporting A-type ATPase complex

cellular_component

A large proton-transporting two-sector ATPase protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane and is found in Archaea.

[ "GOC:mengo_curators", "PMID:15473999", "PMID:24650628" ]

null

[ "A-type ATPase protein complex", "archaeal A-type ATPase protein complex" ]

[ "BROAD", "BROAD" ]

[]

[ "GO:0016469", "GO:1904949" ]

[]

[ "GO:0016469", "GO:1904949" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28017\" xsd:anyURI" ]

tt

2014-09-20T19:13:55Z

false

true

9

GO:1990491

1,990,491

methane biosynthetic process from methanol and hydrogen

biological_process

The chemical reactions and pathways resulting in the formation of methane from methanol and hydrogen.

[ "GOC:mengo_curators", "PMID:16347126" ]

null

[ "methane biosynthesis from methanol and hydrogen", "methanogenesis from methanol and hydrogen" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0019387", "GO:1902421" ]

[]

[ "GO:0019387", "GO:1902421" ]

[]

tt

2014-09-21T01:08:40Z

false

true

1

GO:1990492

1,990,492

obsolete mitotic cell cycle checkpoint inhibiting CAR assembly

biological_process

OBSOLETE. A Mad2-dependent mitotic cell cycle checkpoint which delays cytokinetic actinomycin ring assembly if there is a delay in early M-phase.

[ "PMID:12186944" ]

This term was obsoleted because it does not represent a specific process.

[ "Mad2-dependent mitotic cell cycle checkpoint", "mitotic cell cycle checkpoint inhibiting cytokinetic actomyosin ring assembly" ]

[ "RELATED", "EXACT" ]

[]

vw

2014-09-23T12:43:22Z

true

6

GO:1990494

1,990,494

obsolete regulation of mitotic cytokinesis, actomyosin contractile ring assembly

biological_process

OBSOLETE. Any process that modulates the frequency, rate or extent of mitotic cytokinesis, actomyosin contractile ring assembly.

[ "PMID:18256290" ]

This term was obsoleted at the TermGenie Gatekeeper stage.

[ "regulation of mitotic cytokinesis, actomyosin contractile ring assembly" ]

[ "EXACT" ]

[]

al

2014-09-25T09:04:55Z

true

1