LiteFold/GO · Datasets at Hugging Face

GO:1990728

1,990,728

mitotic spindle assembly checkpoint MAD1-MAD2 complex

cellular_component

A protein complex involved in the assembly of the mitotic checkpoint complex that in turn inhibits the anaphase promoting complex/cyclosome (APC/C). The MAD1 dimer recruits the open form of MAD2 (O-MAD2) turning it into the closed form (C-MAD2) upon binding. C-MAD2 inhibits CDC20, a member of the APC/C, upon release fr...

[ "GOC:bhm", "PMID:12006501", "PMID:22898774" ]

An example of this is MAD1 in human (Q9Y6D9) in PMID:12006501 (inferred from physical interaction).

[ "MAD1-MAD2 complex" ]

[ "EXACT" ]

[]

[ "GO:0032991" ]

[ "has_part GO:1990706", "part_of GO:0005737" ]

[ "has_part", "part_of" ]

[ "GO:1990706", "GO:0005737" ]

[ "GO:0005737", "GO:0032991", "GO:1990706" ]

[]

bhm

2015-04-15T10:14:17Z

false

true

1

GO:1990730

1,990,730

VCP-NSFL1C complex

cellular_component

A protein complex between the ATPase VCP (p97) and its cofactor p47 (NSFL1C). In human, the protein complex consists of one homotrimer of NSFL1C/p47 per homohexamer of VCP/p97.

[ "GOC:bf", "GOC:PARL", "PMID:9214505" ]

null

[ "p97-p47 complex" ]

[ "EXACT" ]

[]

[ "GO:0032991" ]

[ "part_of GO:0005737" ]

[ "part_of" ]

[ "GO:0005737" ]

[ "GO:0005737", "GO:0032991" ]

[]

bf

2015-04-20T12:27:35Z

false

true

7

GO:1990731

1,990,731

obsolete UV-damage excision repair, DNA incision

biological_process

OBSOLETE. A process that results in the endonucleolytic cleavage of the damaged strand of DNA immediately 5' of a UV-induced damage site, and is the first part of a DNA repair process that acts on both cyclobutane pyrimidine dimers (CPDs) and pyrimidine-pyrimidone 6-4 photoproducts (6-4PPs).

[ "PMID:10704216" ]

This term was obsoleted because it represents a molecular function.

[ "alternative excision repair, DNA incision", "DNA incision involved in AER", "DNA incision involved in alternative excision repair", "DNA incision involved in UV-damage excision repair", "DNA incision involved in UV-damaged DNA endonuclease-dependent excision repair", "DNA incision involved in UVDE-depend...

[ "RELATED", "RELATED", "RELATED", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0070914" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22883\" xsd:anyURI" ]

mah

2015-04-21T15:09:04Z

true

7

GO:1990732

1,990,732

pyrenoid

cellular_component

A non-membrane-bounded organelle found within the chloroplasts of algae and hornworts; responsible for carbon dioxide fixation.

[ "GOC:cjm", "GOC:pr", "PMID:23345319", "Wikipedia:Pyrenoid" ]

null

[]

[ "Wikipedia:Pyrenoid" ]

[ "GO:0043232" ]

[ "part_of GO:0009536" ]

[ "part_of" ]

[ "GO:0009536" ]

[ "GO:0009536", "GO:0043232" ]

[]

pr

2015-04-24T12:44:52Z

false

true

7

GO:1990733

1,990,733

titin-telethonin complex

cellular_component

A protein complex formed between the N-terminus of the giant sarcomeric filament protein titin and the Z-disk ligand, telethonin. The complex is part of the Z-disk of the skeletal and cardiac sarcomere. Telethonin binding to titin might be essential for the initial assembly, stabilization and functional integrity of th...

[ "GOC:ame", "PMID:16407954" ]

An example of this are TTN and TCAP in human (UniProt symbols Q8WZ42 and O15273 respectively) in PMID:16407954 (inferred from direct assay).

[ "Titin-Tcap complex" ]

[ "RELATED" ]

[]

[ "GO:0032991" ]

[ "part_of GO:0030018" ]

[ "part_of" ]

[ "GO:0030018" ]

[ "GO:0030018", "GO:0032991" ]

[]

ame

2015-04-24T14:57:08Z

false

true

9

GO:1990734

1,990,734

astral microtubule anchoring at mitotic spindle pole body

biological_process

Any process in which an astral microtubule is maintained in a specific location in a cell by attachment to a mitotic spindle pole body. Microtubules attach to spindle pole bodies at the minus end.

[ "PMID:15004232" ]

null

[]

[ "GO:0034631" ]

[]

[ "GO:0034631" ]

[]

vw

2015-04-28T12:15:18Z

false

true

1

GO:1990735

1,990,735

gamma-tubulin complex localization to mitotic spindle pole body

biological_process

Any process in which a gamma-tubulin complex is transported to, or maintained in, a specific location at a mitotic spindle pole body.

[ "GOC:dos", "GOC:mah", "PMID:11080156" ]

null

[ "establishment and maintenance of gamma-tubulin complex localization to mitotic spindle pole body", "gamma-tubulin complex localisation to mitotic spindle pole body", "gamma-tubulin complex localization to mitotic SPB" ]

[ "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0033566" ]

[]

[ "GO:0033566" ]

[]

mah

2015-04-29T14:40:20Z

false

true

4

GO:1990737

1,990,737

response to manganese-induced endoplasmic reticulum stress

biological_process

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of endoplasmic reticulum stress caused by a manganese stimulus.

[ "GOC:bf", "GOC:PARL", "PMID:23934647" ]

null

[ "manganese-induced ER stress response", "response to manganese-induced ER stress", "response to Mn-induced ER stress" ]

[ "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0034976", "GO:0062197", "GO:0071287" ]

[]

[ "GO:0034976", "GO:0062197", "GO:0071287" ]

[]

bf

2015-04-30T13:48:45Z

false

true

7

GO:1990738

1,990,738

pseudouridine 5'-phosphatase activity

molecular_function

Catalysis of the reaction: pseudouridine 5'-phosphate + H2O = pseudouridine + phosphate.

[ "EC:3.1.3.96", "PMID:20722631" ]

null

[]

[ "EC:3.1.3.96", "RHEA:10944" ]

[ "GO:0016791" ]

[]

[ "GO:0016791" ]

[]

[ "skos:exactMatch EC:3.1.3.96", "skos:exactMatch RHEA:10944", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]

vw

2015-05-02T11:05:50Z

false

true

3

GO:1990740

1,990,740

obsolete non-selective anion channel activity

molecular_function

OBSOLETE. Enables the non-selective, energy-independent passage of anions across a lipid bilayer down a concentration gradient.

[ "GOC:pr", "ISBN:0878937420", "Wikipedia:Ion_channel#Classification_by_type_of_ions" ]

This term was made obsolete because it was added in error.

[ "nonselective anion channel activity" ]

[ "EXACT" ]

[]

pr

2015-05-11T13:25:35Z

true

6

GO:1990741

1,990,741

obsolete non-selective cation channel activity

molecular_function

OBSOLETE. Enables the non-selective, energy-independent passage of cations across a lipid bilayer down a concentration gradient.

[ "GOC:pr", "ISBN:0878937420", "Wikipedia:Ion_channel#Classification_by_type_of_ions" ]

This term was made obsolete because it was added in error.

[ "nonselective cation channel activity" ]

[ "EXACT" ]

[]

pr

2015-05-11T13:27:15Z

true

4

GO:1990742

1,990,742

microvesicle

cellular_component

An extracellular vesicle released from the plasma membrane and ranging in size from about 100 nm to 1000 nm.

[ "GOC:vesicles", "PMID:22418571", "PMID:24009894", "Wikipedia:Microvesicles" ]

null

[ "ectosome", "extracellular microvesicle", "shedding vesicle" ]

[ "EXACT", "EXACT", "BROAD" ]

[]

[ "GO:1903561" ]

[]

[ "GO:1903561" ]

[]

pr

2015-05-13T13:44:52Z

false

true

8

GO:1990743

1,990,743

protein sialylation

biological_process

A protein modification process that results in the addition of a sialic acid unit to the end of an oligosaccharide chain in a glycoprotein.

[ "PMID:21930713" ]

null

[]

[ "gocheck_obsoletion_candidate" ]

[]

[ "GO:0036211", "GO:0097503" ]

[]

[ "GO:0036211", "GO:0097503" ]

[]

sl

2015-05-14T20:18:28Z

false

true

7

GO:1990745

1,990,745

EARP complex

cellular_component

A quatrefoil tethering complex required for endocytic recycling.

[ "PMID:25799061" ]

null

[]

[ "GO:0032991" ]

[ "part_of GO:0055037" ]

[ "part_of" ]

[ "GO:0055037" ]

[ "GO:0032991", "GO:0055037" ]

[]

sp

2015-05-15T10:23:25Z

false

true

6

GO:1990747

1,990,747

pancreatic trypsinogen secretion

biological_process

The regulated release of trypsinogen from the cells of the exocrine pancreas.

[ "PMID:12771515" ]

null

[ "pancreatic trypsinogen release" ]

[ "EXACT" ]

[]

[ "GO:0009306" ]

[ "part_of GO:0030157" ]

[ "part_of" ]

[ "GO:0030157" ]

[ "GO:0009306", "GO:0030157" ]

[]

sl

2015-05-15T17:41:25Z

false

true

3

GO:1990748

1,990,748

cellular detoxification

biological_process

Any process carried out at the cellular level that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.

[ "GOC:vw" ]

null

[]

[ "GO:0009987", "GO:0098754" ]

[ "part_of GO:0097237" ]

[ "part_of" ]

[ "GO:0097237" ]

[ "GO:0009987", "GO:0097237", "GO:0098754" ]

[]

vw

2015-05-18T16:17:46Z

false

true

6

GO:1990749

1,990,749

polynucleotide adenylyltransferase activator activity

molecular_function

Increases the activity of the enzyme polynucleotide adenylyltransferase.

[ "GOC:kmv", "PMID:19460348" ]

null

[]

[ "GO:0008047" ]

[ "positively_regulates GO:1990817" ]

[ "positively_regulates" ]

[ "GO:1990817" ]

[ "GO:0008047", "GO:1990817" ]

[]

kmv

2015-05-19T15:02:39Z

false

true

3

GO:1990750

1,990,750

obsolete axon shaft

cellular_component

OBSOLETE. Main portion of an axon, excluding terminal, spines, or dendrites.

[ "PMID:11264310", "PMID:24312009" ]

This term was made obsolete because it was added in error.

[ "axonal shaft" ]

[ "EXACT" ]

[]

[ "GO:0044304" ]

[]

sl

2015-05-21T17:46:18Z

true

8

GO:1990751

1,990,751

Schwann cell chemotaxis

biological_process

The directed movement of a Schwann cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).

[ "PMID:16203995" ]

null

[]

[ "GO:0036135", "GO:0060326" ]

[]

[ "GO:0036135", "GO:0060326" ]

[]

sl

2015-05-21T19:19:09Z

false

true

2

GO:1990752

1,990,752

microtubule end

cellular_component

Any end of a microtubule. Microtubule ends differ in that the so-called microtubule plus-end is the one that preferentially grows by polymerization, with respect to the minus-end.

[ "GOC:pr" ]

This term should be used when it is not possible to distinguish between the two microtubule ends, e.g. during image annotation. Whenever possible, please annotate to one of the more specific children GO:0035371 'microtubule plus-end' or GO:0036449 'microtubule minus-end'.

[]

[ "GO:0110165" ]

[ "part_of GO:0005874" ]

[ "part_of" ]

[ "GO:0005874" ]

[ "GO:0005874", "GO:0110165" ]

[]

pr

2015-05-25T12:50:31Z

false

true

2

GO:1990753

1,990,753

equatorial cell cortex

cellular_component

The region of the cell cortex in a mitotically dividing cell that flanks the central spindle and corresponds to the site of actomyosin ring formation that results in cleavage furrow formation and ingression.

[ "GOC:kmv", "PMID:16352658", "PMID:22552143", "PMID:23750214", "PMID:25898168" ]

null

[]

[ "GO:0099738" ]

[ "part_of GO:0032153" ]

[ "part_of" ]

[ "GO:0032153" ]

[ "GO:0032153", "GO:0099738" ]

[]

kmv

2015-05-27T19:12:41Z

false

true

3

GO:1990755

1,990,755

mitotic spindle microtubule depolymerization

biological_process

The removal of tubulin heterodimers from one or both ends of a microtubule that is part of the mitotic spindle.

[ "PMID:25253718" ]

null

[ "mitotic spindle microtubule depolymerisation" ]

[ "EXACT" ]

[]

[ "GO:0007019" ]

[]

[ "GO:0007019" ]

[]

mah

2015-05-28T15:42:06Z

false

true

9

GO:1990756

1,990,756

ubiquitin-like ligase-substrate adaptor activity

molecular_function

The binding activity of a molecule that brings together a ubiquitin-like ligase (including ubiquitin ligase and UFM1 ligase) and its substrate. Usually mediated by F-box BTB/POZ domain proteins.

[ "PMID:24658274" ]

null

[ "protein binding, bridging involved in substrate recognition for ubiquitination", "ubiquitin ligase substrate adaptor", "ubiquitin ligase-substrate adaptor activity", "UFM1 ligase-substrate adaptor activity" ]

[ "EXACT", "EXACT", "NARROW", "NARROW" ]

[]

[ "GO:0140767" ]

[]

[ "GO:0140767" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/18655\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27325\" xsd:anyURI" ]

vw

2015-06-01T08:35:16Z

false

true

2

GO:1990757

1,990,757

ubiquitin ligase activator activity

molecular_function

Binds to and increases the activity of a ubiquitin ligase.

[ "GOC:dph", "PMID:25619242" ]

null

[ "mitotic anaphase-promoting complex activator activity" ]

[ "NARROW" ]

[ "GO:0061636" ]

[]

[ "GO:0097027" ]

[ "part_of GO:1904668" ]

[ "part_of" ]

[ "GO:1904668" ]

[ "GO:0097027", "GO:1904668" ]

[]

vw

2015-06-01T08:53:04Z

false

true

5

GO:1990758

1,990,758

mitotic sister chromatid biorientation

biological_process

The mitotic cell cycle process in which sister chromatids establish stable, end-on attachments to the plus ends of microtubules emanating from opposite spindle poles, oriented such that separation can proceed. This is the final step in metaphase plate congression.

[ "PMID:15309047", "PMID:26258632", "PMID:26705896" ]

null

[]

[ "GO:0031134", "GO:0051315" ]

[ "has_part GO:0051010" ]

[ "has_part" ]

[ "GO:0051010" ]

[ "GO:0031134", "GO:0051010", "GO:0051315" ]

[ "GO:0031134", "part_of GO:0000278" ]

[]

vw

2015-06-02T12:36:17Z

false

true

2

GO:1990760

1,990,760

osmolarity-sensing monoatomic cation channel activity

molecular_function

Enables the transmembrane transfer of a monoatomic cation by a channel that opens when a change in the osmolarity occurs in the extracellular space of the cell in which the cation channel resides.

[ "PMID:18279313" ]

null

[ "osmolarity-sensing cation channel activity" ]

[ "BROAD" ]

[]

[ "GO:0005034", "GO:0005261", "GO:0022836" ]

[]

[ "GO:0005034", "GO:0005261", "GO:0022836" ]

[]

sl

2015-06-05T21:58:50Z

false

true

2

GO:1990761

1,990,761

growth cone lamellipodium

cellular_component

A thin sheetlike process extended by the leading edge of an axonal or dendritic growth cone; contains a dense meshwork of actin filaments.

[ "GOC:dos", "PMID:25598228" ]

null

[]

[ "GO:0030027", "GO:0043005" ]

[ "part_of GO:0030426" ]

[ "part_of" ]

[ "GO:0030426" ]

[ "GO:0030027", "GO:0030426", "GO:0043005" ]

[]

sl

2015-06-05T22:31:19Z

false

true

8

GO:1990763

1,990,763

arrestin family protein binding

molecular_function

Binding to a member of the arrestin family, proteins involved in agonist-mediated desensitization of G protein-coupled receptors.

[ "PMID:23911909" ]

null

[]

[ "GO:0005515" ]

[]

[ "GO:0005515" ]

[]

sl

2015-06-09T23:29:42Z

false

true

1

GO:1990764

1,990,764

myofibroblast contraction

biological_process

The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of a myofibroblast.

[ "PMID:19239477" ]

null

[ "MF contraction", "MFB contraction" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0070252" ]

[]

[ "GO:0070252" ]

[]

sl

2015-06-09T23:43:09Z

false

true

6

GO:1990765

1,990,765

colon smooth muscle contraction

biological_process

A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry of the large intestine, exclusive of the rectum. The colon is that part of the large intestine that connects the small intestine to the rectum.

[ "PMID:24170253" ]

null

[]

[ "GO:0006939" ]

[ "part_of GO:0014827" ]

[ "part_of" ]

[ "GO:0014827" ]

[ "GO:0006939", "GO:0014827" ]

[]

sl

2015-06-10T18:29:21Z

false

true

8

GO:1990767

1,990,767

prostaglandin receptor internalization

biological_process

The process that results in the uptake of a prostaglandin receptor into an endocytic vesicle.

[ "PMID:15937517" ]

null

[]

[ "GO:0002031" ]

[]

[ "GO:0002031" ]

[]

sl

2015-06-10T19:14:08Z

false

true

8

GO:1990768

1,990,768

gastric mucosal blood circulation

biological_process

The flow of blood through the gastric mucosa of an animal, enabling the transport of nutrients and the removal of waste products.

[ "PMID:10807413" ]

null

[ "stomach mucosal blood circulation" ]

[ "EXACT" ]

[]

[ "GO:0008015" ]

[]

[ "GO:0008015" ]

[]

sl

2015-06-10T20:11:09Z

false

true

3

GO:1990770

1,990,770

small intestine smooth muscle contraction

biological_process

A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry in the intestine between the stomach and the large intestine.

[ "PMID:11991626" ]

null

[]

[ "GO:0006939" ]

[ "part_of GO:0014827" ]

[ "part_of" ]

[ "GO:0014827" ]

[ "GO:0006939", "GO:0014827" ]

[]

sl

2015-06-11T18:02:33Z

false

true

6

GO:1990771

1,990,771

clathrin-dependent extracellular exosome endocytosis

biological_process

The clathrin-mediated endocytosis of an extracellular exosome.

[ "PMID:24951588" ]

null

[ "clathrin-mediated extracellular exosome endocytosis", "exosome related" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0051650", "GO:0072583" ]

[]

[ "GO:0051650", "GO:0072583" ]

[]

sl

2015-06-15T17:03:57Z

false

true

9

GO:1990772

1,990,772

substance P secretion

biological_process

The regulated release of substance P, a peptide hormone that is involved in neurotransmission, inflammation, and antimicrobial activity.

[ "PMID:11278900" ]

null

[]

[ "GO:0030072" ]

[]

[ "GO:0030072" ]

[]

sl

2015-06-15T18:17:30Z

false

true

3

GO:1990773

1,990,773

matrix metallopeptidase secretion

biological_process

The regulated release of matrix metallopeptidases, a family of zinc-dependent endopeptidases that can degrade extracellular matrix proteins and process other types of proteins.

[ "PMID:8679543" ]

null

[ "matrix metalloproteinase secretion", "MMP secretion" ]

[ "NARROW", "EXACT" ]

[]

[ "GO:0009306" ]

[]

[ "GO:0009306" ]

[]

sl

2015-06-15T19:12:06Z

false

true

5

GO:1990775

1,990,775

endothelin production

biological_process

The appearance of a endothelin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions.

[ "PMID:15560120" ]

null

[ "EDN1 production", "EDN2 production", "EDN3 production", "endothelin secretion", "endothelin-1 secretion", "endothelin-2 production", "endothelin-3 production" ]

[ "NARROW", "NARROW", "NARROW", "NARROW", "NARROW", "NARROW", "NARROW" ]

[]

[ "gocheck_do_not_annotate" ]

[]

[ "GO:0001816" ]

[]

[ "GO:0001816" ]

[]

sl

2015-06-15T23:13:18Z

false

true

8

GO:1990777

1,990,777

lipoprotein particle

cellular_component

A spherical particle containing non-covalently associated proteins and lipids. Examples are plasma lipoprotein particles which transport lipids in the blood or lymph.

[ "GOC:vesicles" ]

null

[]

[ "GO:0032994" ]

[]

[ "GO:0032994" ]

[]

pr

2015-06-18T08:42:53Z

false

true

2

GO:1990779

1,990,779

glycoprotein Ib-IX-V complex

cellular_component

A transmembrane signaling receptor complex found exclusively on platelets. Involved in haemostasis and thrombosis where it aids blood coagulation.

[ "GOC:bhm", "PMID:1730602", "PMID:23336709", "PMID:25297919" ]

An example of this is GB1BA in human (P07359) in PMID:1730602 (inferred from direct assay).

[ "CD42", "GPIb-IX-V complex", "GPIb-V-IX complex" ]

[ "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0090665", "GO:0098802" ]

[]

[ "GO:0090665", "GO:0098802" ]

[]

bhm

2015-06-23T11:22:12Z

false

true

5

GO:1990780

1,990,780

cytoplasmic side of dendritic spine plasma membrane

cellular_component

The leaflet of the plasma membrane in the dendritic spine region that faces the cytoplasm, including any protein embedded in, attached to, or peripherally associated with it.

[ "PMID:9275233" ]

null

[]

[ "GO:0009898" ]

[ "part_of GO:0032591" ]

[ "part_of" ]

[ "GO:0032591" ]

[ "GO:0009898", "GO:0032591" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31515\" xsd:anyURI" ]

sl

2015-06-23T18:35:39Z

false

true

8

GO:1990781

1,990,781

response to immobilization stress combined with electrical stimulus

biological_process

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus given while being held immobile.

[ "PMID:17008368" ]

null

[]

[ "GO:0035902", "GO:0051602" ]

[]

[ "GO:0035902", "GO:0051602" ]

[]

sl

2015-06-23T20:30:42Z

false

true

2

GO:1990782

1,990,782

protein tyrosine kinase binding

molecular_function

Binding to protein tyrosine kinase.

[ "PMID:25499537" ]

null

[ "tyrosine kinase binding" ]

[ "EXACT" ]

[]

[ "GO:0019901" ]

[]

[ "GO:0019901" ]

[]

sl

2015-06-23T20:50:58Z

false

true

6

GO:1990784

1,990,784

response to dsDNA

biological_process

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded DNA stimulus.

[ "PMID:10051633" ]

null

[ "response to double-stranded DNA" ]

[ "EXACT" ]

[]

[ "GO:1901698" ]

[]

[ "GO:1901698" ]

[]

sl

2015-06-24T17:54:13Z

false

true

7

GO:1990785

1,990,785

response to water-immersion restraint stress

biological_process

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of water immersion while being held immobile.

[ "PMID:10882227" ]

null

[ "response to immobilization stress combined with water immersion" ]

[ "EXACT" ]

[]

[ "GO:0035902" ]

[]

[ "GO:0035902" ]

[]

sl

2015-06-24T18:27:28Z

false

true

1

GO:1990786

1,990,786

cellular response to dsDNA

biological_process

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded DNA stimulus.

[ "PMID:10051633" ]

null

[]

[ "GO:1901699", "GO:1990784" ]

[]

[ "GO:1901699", "GO:1990784" ]

[]

sl

2015-06-24T22:48:25Z

false

true

8

GO:1990787

1,990,787

obsolete negative regulation of hh target transcription factor activity

biological_process

OBSOLETE. Any process that decreases the activity of a transcription factor that activates transcription of Hedgehog-target genes in response to Smoothened signaling. In Drosophila, Cubitus interruptus (Ci) is the only identified transcription factor so far in the Hedgehog signaling pathway. In vertebrates members of t...

[ "GOC:bhm", "PMID:24311597" ]

The reason for obsoletion is that this term represents a molecular function.

[ "negative regulation of hedgehog target transcription factor" ]

[ "EXACT" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30856\" xsd:anyURI" ]

bhm

2015-06-26T09:54:29Z

true

7

GO:1990788

1,990,788

GLI-SUFU complex

cellular_component

A protein repressing GLI's transcription factor activity when SMO signaling is inactive. Upon ligand binding to the upstream receptor PTC (Patched) GLI dissociates from SUFU and activates transcription of hedgehog-target genes. In mammals it consists of SUFU and one of the GLI family proteins.

[ "GOC:bhm", "PMID:24311597" ]

An example of this is SUFU in human (Q9UMX1) in PMID:24311597 (inferred from direct assay).

[]

[ "GO:0032991" ]

[ "part_of GO:0005829" ]

[ "part_of" ]

[ "GO:0005829" ]

[ "GO:0005829", "GO:0032991" ]

[]

bhm

2015-06-26T13:49:47Z

false

true

7

GO:1990790

1,990,790

response to glial cell derived neurotrophic factor

biological_process

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glial cell derived neurotrophic factor stimulus.

[ "PMID:20877310" ]

null

[ "response to astrocyte-derived trophic factor", "response to ATF", "response to GDNF" ]

[ "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0070848" ]

[]

[ "GO:0070848" ]

[]

sl

2015-07-02T19:47:05Z

false

true

8

GO:1990791

1,990,791

dorsal root ganglion development

biological_process

The process whose specific outcome is the progression of a dorsal root ganglion over time, from its formation to the mature structure.

[ "PMID:18583150" ]

null

[ "DRG development" ]

[ "EXACT" ]

[]

[ "GO:0061548" ]

[]

[ "GO:0061548" ]

[]

sl

2015-07-02T22:09:54Z

false

true

7

GO:1990792

1,990,792

cellular response to glial cell derived neurotrophic factor

biological_process

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glial cell derived neurotrophic factor stimulus.

[ "PMID:20877310" ]

null

[ "cellular response to astrocyte-derived trophic factor", "cellular response to ATF", "cellular response to GDNF" ]

[ "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0071363", "GO:1990790" ]

[]

[ "GO:0071363", "GO:1990790" ]

[]

sl

2015-07-06T15:27:38Z

false

true

5

GO:1990793

1,990,793

substance P secretion, neurotransmission

biological_process

The controlled release of substance P by a cell, in which the substance P acts as a neurotransmitter.

[ "PMID:15292051" ]

null

[]

[ "GO:0007269", "GO:1990772" ]

[]

[ "GO:0007269", "GO:1990772" ]

[]

sl

2015-07-09T19:43:36Z

false

true

9

GO:1990794

1,990,794

basolateral part of cell

cellular_component

The region of a cell situated by the cell sides which interface adjacent cells and near the base. Often used in reference to animal polarized epithelial cells.

[ "PMID:18495799" ]

null

[]

[ "GO:0110165" ]

[ "part_of GO:0045178", "part_of GO:0097574" ]

[ "part_of", "part_of" ]

[ "GO:0045178", "GO:0097574" ]

[ "GO:0045178", "GO:0097574", "GO:0110165" ]

[]

sl

2015-07-09T20:31:50Z

false

true

8

GO:1990795

1,990,795

rod bipolar cell terminal bouton

cellular_component

A specialized region of the axon terminus portion of a rod bipolar axon. A rod bipolar cell is a neuron found in the retina and having connections with rod photoreceptor cells and neurons in the inner plexiform layer.

[ "PMID:19883736" ]

null

[]

[ "GO:0043195" ]

[]

[ "GO:0043195" ]

[]

sl

2015-07-09T21:11:53Z

false

true

6

GO:1990796

1,990,796

photoreceptor cell terminal bouton

cellular_component

A specialized region of the axon terminus portion of a photoreceptor cell axon. A photoreceptor cell is a neuron specialized to detect and transduce light.

[ "PMID:19883736" ]

null

[]

[ "GO:0043195" ]

[]

[ "GO:0043195" ]

[]

sl

2015-07-09T21:33:40Z

false

true

3

GO:1990797

1,990,797

obsolete cholecystokinin secretion

biological_process

OBSOLETE. The controlled release of cholecystokinin from a cell. Cholecystokinin is a peptide hormone that participates in pancreatic enzyme release in the gut and is also found in the brain.

[ "PMID:2755938" ]

This term was obsoleted at the TermGenie Gatekeeper stage.

[ "CCK secretion" ]

[ "EXACT" ]

[]

sl

2015-07-09T23:14:23Z

true

2

GO:1990798

1,990,798

pancreas regeneration

biological_process

The regrowth of a destroyed pancreas.

[ "PMID:1985964" ]

null

[]

[ "GO:0031100" ]

[]

[ "GO:0031100" ]

[]

sl

2015-07-10T22:53:53Z

false

true

7

GO:1990799

1,990,799

mitochondrial tRNA wobble position uridine thiolation

biological_process

The process in which a uridine residue at position 34 in the anticodon of a mitochondrial tRNA is post-transcriptionally thiolated at the C2 position. This process involves transfer of a sulfur from cysteine to position C2 by several steps.

[ "PMID:15509579" ]

null

[]

[ "GO:0002143", "GO:0070899", "GO:0070903" ]

[]

[ "GO:0002143", "GO:0070899", "GO:0070903" ]

[]

vw

2015-07-13T08:15:15Z

false

true

5

GO:1990801

1,990,801

obsolete protein phosphorylation involved in mitotic spindle assembly

biological_process

OBSOLETE. Any protein phosphorylation that is involved in mitotic spindle assembly.

[ "GO_REF:0000060", "GOC:rb", "GOC:TermGenie", "PMID:21558801" ]

This term has been obsoleted because it represents a GO-CAM model.

[ "protein amino acid phosphorylation involved in mitotic spindle assembly", "protein amino acid phosphorylation involved in spindle assembly involved in mitosis", "protein phosphorylation involved in spindle assembly involved in mitosis" ]

[ "EXACT", "EXACT", "EXACT" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/14137\" xsd:anyURI" ]

rb

2015-07-16T18:36:05Z

true

5

GO:1990802

1,990,802

obsolete protein phosphorylation involved in DNA double-strand break processing

biological_process

OBSOLETE. Any protein phosphorylation that is required for DNA double-strand break processing.

[ "GO_REF:0000060", "GOC:rb", "GOC:TermGenie", "PMID:21841787" ]

This term has been obsoleted because it represents a GO-CAM model.

[ "protein amino acid phosphorylation involved in DNA double-strand break processing" ]

[ "EXACT" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/14137\" xsd:anyURI" ]

rb

2015-07-16T20:43:39Z

true

1

GO:1990803

1,990,803

obsolete protein phosphorylation involved in protein localization to spindle microtubule

biological_process

OBSOLETE. Any protein phosphorylation process involved in localizing a protein to the spindle microtubule.

[ "GO_REF:0000060", "GOC:rb", "GOC:TermGenie", "PMID:22521784" ]

This term has been obsoleted because it represents a GO-CAM model.

[ "protein amino acid phosphorylation involved in protein localisation in spindle microtubule", "protein amino acid phosphorylation involved in protein localisation to spindle microtubule", "protein amino acid phosphorylation involved in protein localization in spindle microtubule", "protein amino acid phosphor...

[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/14137\" xsd:anyURI" ]

rb

2015-07-16T21:09:07Z

true

2

GO:1990805

1,990,805

central cylinder

cellular_component

A scaffolding structure present within the inner region of the ciliary transition zone. The central cylinder lies between the outer doublet and inner singlet microtubules.

[ "GOC:kmv", "PMID:2428682", "PMID:26124290" ]

null

[]

[ "GO:0110165" ]

[ "part_of GO:0035869" ]

[ "part_of" ]

[ "GO:0035869" ]

[ "GO:0035869", "GO:0110165" ]

[]

kmv

2015-07-17T17:48:17Z

false

true

4

GO:1990806

1,990,806

ligand-gated ion channel signaling pathway

biological_process

The series of molecular signals initiated by activation of a ligand-gated ion channel on the surface of a cell. The pathway begins with binding of an extracellular ligand to a ligand-gated ion channel and ends with a molecular function that directly regulates a downstream cellular process, e.g. transcription.

[ "GOC:bhm", "PMID:25869137" ]

null

[ "ligand-gated ion channel signalling pathway" ]

[ "EXACT" ]

[]

[ "GO:0007165" ]

[ "has_part GO:0015276" ]

[ "has_part" ]

[ "GO:0015276" ]

[ "GO:0007165", "GO:0015276" ]

[ "GO:0007165", "has_part GO:0015276" ]

[]

bhm

2015-07-20T12:09:56Z

false

true

5

GO:1990807

1,990,807

obsolete protein N-acetyltransferase activity

molecular_function

OBSOLETE. Catalysis of the transfer of an acetyl group to a nitrogen atom on the amino acid of a protein.

[ "GOC:dph" ]

This term was obsoleted at the TermGenie Gatekeeper stage.

[]

vw

2015-07-20T15:19:23Z

true

9

GO:1990810

1,990,810

microtubule anchoring at mitotic spindle pole body

biological_process

Any process in which a microtubule is maintained in a specific location in a cell by attachment to a mitotic spindle pole body. Microtubules attach to spindle pole bodies at the minus end.

[ "PMID:17486116" ]

null

[]

[ "GO:0034631", "GO:1902850" ]

[ "part_of GO:0090307" ]

[ "part_of" ]

[ "GO:0090307" ]

[ "GO:0034631", "GO:0090307", "GO:1902850" ]

[]

vw

2015-07-24T12:52:25Z

false

true

9

GO:1990811

1,990,811

MWP complex

cellular_component

A protein ternary complex that anchors microtubule minus ends to mitotic spindle pole bodies. The founding complex contains a microtubule anchoring protein (Msd1 in fission yeast), A WD-repeat Wdr8 family protein and and a minus end-directed kinesin.

[ "PMID:25987607", "PMID:29021344" ]

null

[ "Msd1-Wdr8-Pkl1 complex" ]

[ "EXACT" ]

[]

[ "GO:0032991" ]

[]

[ "GO:0032991" ]

[]

vw

2015-07-24T13:34:31Z

false

true

6

GO:1990812

1,990,812

growth cone filopodium

cellular_component

A thin, stiff protrusion extended by the leading edge of an axonal or dendritic growth cone.

[ "PMID:25598228" ]

null

[]

[ "GO:0030175", "GO:0043005" ]

[ "part_of GO:0030426" ]

[ "part_of" ]

[ "GO:0030426" ]

[ "GO:0030175", "GO:0030426", "GO:0043005" ]

[]

sl

2015-07-24T22:35:16Z

false

true

6

GO:1990813

1,990,813

meiotic centromeric cohesion protection in anaphase I

biological_process

The process in which the association between sister chromatids of a replicated chromosome centromeric region is maintained during homologous chromosome segregation at meiotic anaphase I after cohesin is cleaved by separase along the arm regions.

[ "PMID:14730319", "PMID:25533956" ]

null

[ "anaphase cohesion protection", "protection of centromeric cohesion during meiotic anaphase I" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0035875", "GO:1903046" ]

[ "part_of GO:0045143" ]

[ "part_of" ]

[ "GO:0045143" ]

[ "GO:0035875", "GO:0045143", "GO:1903046" ]

[]

vw

2015-07-28T16:15:31Z

false

true

9

GO:1990816

1,990,816

vacuole-mitochondrion membrane contact site

cellular_component

A zone of apposition between the vacuolar membrane and the mitochondrial outer membrane, important for transfer of lipids between the two organelles.

[ "PMID:25026035", "PMID:25026036" ]

null

[ "vacuole and mitochondria patch", "vCLAMP" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0044232" ]

[]

[ "GO:0044232" ]

[]

mcc

2015-07-29T21:06:41Z

false

true

1

GO:1990817

1,990,817

poly(A) RNA polymerase activity

molecular_function

Catalysis of the reaction: ATP + RNA(n) = diphosphate + RNA(n)-3'-adenine ribonucleotide. The primer may be an RNA or DNA fragment, or oligo(A) bearing a 3'-OH terminal group.

[ "PMID:13965521", "RHEA:11332" ]

null

[ "NTP polymerase activity", "poly(A) polymerase activity", "polynucleotide adenylyltransferase activity", "RNA adenylating enzyme", "RNA adenyltransferase activity", "RNA adenylyltransferase activity" ]

[ "BROAD", "RELATED", "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "EC:2.7.7.19", "MetaCyc:POLYNUCLEOTIDE-ADENYLYLTRANSFERASE-RXN", "Reactome:R-HSA-9833031 \"Polyadenylation of respiratory syncytial virus subgenomic positive-sense mRNAs\"", "Reactome:R-HSA-9936998 \"MTPAP polyadenylates mitochondrial mRNA\"", "Reactome:R-HSA-9970189 \"PABPN1-stimulated PAPOL synthesizes po...

[ "GO:0070566" ]

[]

[ "GO:0070566" ]

[]

[ "skos:exactMatch EC:2.7.7.19", "skos:exactMatch RHEA:11332", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24859\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]

vw

2015-07-31T09:38:31Z

false

true

7

GO:1990818

1,990,818

L-arginine transmembrane export from vacuole

biological_process

The directed movement of L-arginine out of the vacuole, across the vacuolar membrane.

[ "PMID:26083598" ]

null

[]

[ "GO:0015695", "GO:0032974", "GO:1902475" ]

[]

[ "GO:0015695", "GO:0032974", "GO:1902475" ]

[]

vw

2015-08-06T15:06:33Z

false

true

8

GO:1990819

1,990,819

mating projection actin fusion focus

cellular_component

A focus at the mating projection tip where the cell wall is degraded during conjugation with cellular fusion. Actin filaments form an aster-like structure from this location.

[ "PMID:25825517" ]

null

[ "actin fusion focus" ]

[ "BROAD" ]

[]

[ "GO:0110165" ]

[ "has_part GO:0005884", "part_of GO:0015629", "part_of GO:0043332" ]

[ "has_part", "part_of", "part_of" ]

[ "GO:0005884", "GO:0015629", "GO:0043332" ]

[ "GO:0005884", "GO:0015629", "GO:0043332", "GO:0110165" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21449\" xsd:anyURI" ]

al

2015-08-10T16:52:15Z

false

true

1

GO:1990820

1,990,820

response to mitotic DNA integrity checkpoint signaling

biological_process

A process that occurs in response to signals generated as a result of mitotic DNA integrity checkpoint signaling.

[ "PMID:7548844" ]

null

[ "response to signal involved in mitotic DNA integrity checkpoint" ]

[ "EXACT" ]

[]

[ "GO:0072402", "GO:0072414" ]

[]

[ "GO:0072402", "GO:0072414" ]

[]

mah

2015-08-14T10:25:46Z

false

true

5

GO:1990822

1,990,822

basic amino acid transmembrane transport

biological_process

The directed movement of basic amino acids from one side of a membrane to the other.

[ "GOC:dph", "GOC:vw" ]

null

[]

[ "GO:0003333", "GO:0015802" ]

[]

[ "GO:0003333", "GO:0015802" ]

[]

vw

2015-08-19T07:47:00Z

false

true

2

GO:1990823

1,990,823

response to leukemia inhibitory factor

biological_process

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukemia inhibitory factor stimulus.

[ "PMID:12801913" ]

null

[ "response to CDF", "response to cholinergic differentiation factor", "response to LIF" ]

[ "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0034097" ]

[]

[ "GO:0034097" ]

[]

sl

2015-08-19T16:44:21Z

false

true

5

GO:1990824

1,990,824

obsolete magnesium-dependent protein complex

cellular_component

OBSOLETE. A protein complex that depends on magnesium in order for one or more of its components to remain a part of the complex.

[ "PMID:10220587" ]

This term was obsoleted at the TermGenie Gatekeeper stage.

[]

sl

2015-08-19T17:11:43Z

true

9

GO:1990825

1,990,825

sequence-specific mRNA binding

molecular_function

Binding to messenger RNA (mRNA) of a specific nucleotide composition or a specific sequence motif.

[ "PMID:11886857" ]

null

[]

[ "GO:0003729" ]

[]

[ "GO:0003729" ]

[]

sl

2015-08-19T17:42:50Z

false

true

4

GO:1990826

1,990,826

nucleoplasmic periphery of the nuclear pore complex

cellular_component

Nucleoplasm situated in close proximity and peripheral to a nuclear pore complex.

[ "PMID:10633080" ]

null

[ "associated with the nuclear pore" ]

[ "RELATED" ]

[]

[ "GO:0110165" ]

[ "part_of GO:0005654" ]

[ "part_of" ]

[ "GO:0005654" ]

[ "GO:0005654", "GO:0110165" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21774\" xsd:anyURI" ]

sl

2015-08-19T18:26:26Z

false

true

4

GO:1990827

1,990,827

deaminase binding

molecular_function

Binding to an enzyme that catalyzes the removal of an amino group from a substrate, producing ammonia (NH3).

[ "PMID:9792439" ]

null

[]

[ "GO:0019899" ]

[]

[ "GO:0019899" ]

[]

sl

2015-08-19T23:48:32Z

false

true

7

GO:1990828

1,990,828

hepatocyte dedifferentiation

biological_process

The process in which a hepatocyte (specialized epithelial cell of the liver) loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem ce...

[ "PMID:20102719" ]

null

[]

[ "GO:0043697" ]

[]

[ "GO:0043697" ]

[]

sl

2015-08-20T14:14:57Z

false

true

8

GO:1990829

1,990,829

C-rich single-stranded DNA binding

molecular_function

Binding to C-rich, single-stranded DNA.

[ "PMID:8127654" ]

null

[ "C-rich ssDNA binding" ]

[ "EXACT" ]

[]

[ "GO:0003697" ]

[]

[ "GO:0003697" ]

[]

sl

2015-08-20T16:05:12Z

false

true

8

GO:1990830

1,990,830

cellular response to leukemia inhibitory factor

biological_process

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukemia inhibitory factor stimulus.

[ "PMID:12801913" ]

null

[ "cellular response to CDF", "cellular response to cholinergic differentiation factor" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0071345", "GO:1990823" ]

[]

[ "GO:0071345", "GO:1990823" ]

[]

sl

2015-08-20T19:30:38Z

false

true

7

GO:1990831

1,990,831

cellular response to carcinoembryonic antigen

biological_process

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carcinoembryonic antigen stimulus. The carcinoembryonic antigens represent a family of glycoproteins.

[ "PMID:10202129", "PMID:14597422" ]

null

[ "cellular response to pregnancy specific glycoprotein" ]

[ "EXACT" ]

[]

[ "GO:1904588" ]

[]

[ "GO:1904588" ]

[]

sl

2015-08-20T19:43:12Z

false

true

5

GO:1990832

1,990,832

slow axonal transport

biological_process

The directed slow movement of non-membranous molecules in nerve cell axons. It is comprised of a Slow Component a (SCa) and a Slow Component b (SCb) which differ in transport rates and protein composition.

[ "PMID:6378920" ]

null

[]

[ "GO:0008088" ]

[]

[ "GO:0008088" ]

[]

sl

2015-08-21T17:27:32Z

false

true

6

GO:1990834

1,990,834

response to odorant

biological_process

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an odorant stimulus. An odorant is any substance capable of stimulating the sense of smell.

[ "PMID:11268007" ]

null

[]

[ "GO:0042221" ]

[]

[ "GO:0042221" ]

[]

sl

2015-08-21T18:51:52Z

false

true

1

GO:1990835

1,990,835

obsolete insulin-like growth factor production

biological_process

OBSOLETE. The appearance of an insulin-like growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.

[ "PMID:21993393" ]

This term was obsoleted at the TermGenie Gatekeeper stage.

[ "IGF production" ]

[ "RELATED" ]

[]

sl

2015-08-24T16:30:53Z

true

8

GO:1990836

1,990,836

lysosomal matrix

cellular_component

A matrix composed of supramolecular assemblies of lysosomal enzymes and lipids which forms at a pH of 5.0 within the lysosome.

[ "PMID:9395337" ]

null

[]

[ "GO:0110165" ]

[ "part_of GO:0043202" ]

[ "part_of" ]

[ "GO:0043202" ]

[ "GO:0043202", "GO:0110165" ]

[]

sl

2015-08-25T17:04:12Z

false

true

1

GO:1990837

1,990,837

sequence-specific double-stranded DNA binding

molecular_function

Binding to double-stranded DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA, e.g. promotor binding or rDNA binding.

[ "GOC:dos", "GOC:sl" ]

null

[ "sequence-specific dsDNA binding" ]

[ "EXACT" ]

[]

[ "GO:0003690", "GO:0043565" ]

[]

[ "GO:0003690", "GO:0043565" ]

[]

sl

2015-08-25T17:30:06Z

false

true

8

GO:1990838

1,990,838

poly(U)-specific exoribonuclease activity, producing 3' uridine cyclic phosphate ends

molecular_function

Catalysis of the reaction: a 3'-end uridylyl-uridine-RNA = a 3'-end 2',3'-cyclophospho-uridine-RNA + uridine.

[ "PMID:23022480", "RHEA:46052" ]

null

[]

[ "RHEA:46052" ]

[ "GO:0000175" ]

[]

[ "GO:0000175" ]

[]

[ "skos:exactMatch RHEA:46052", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30714\" xsd:anyURI" ]

al

2015-08-26T10:24:51Z

false

true

4

GO:1990839

1,990,839

response to endothelin

biological_process

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an endothelin stimulus. Endothelin is any of three secretory vasoconstrictive peptides (endothelin-1, -2, -3).

[ "PMID:16365184" ]

null

[]

[ "GO:0043434" ]

[]

[ "GO:0043434" ]

[]

sl

2015-08-27T19:37:52Z

false

true

7

GO:1990840

1,990,840

response to lectin

biological_process

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lectin stimulus. A lectin is a carbohydrate-binding protein, highly specific for binding sugar moieties.

[ "PMID:25996210", "PMID:26306444" ]

This term refers to endogenous (evolved) responses to lectins (endogenous or exogenous), it does not cover the events that happen due to lectin toxicity.

[]

[ "GO:0009607" ]

[]

[ "GO:0009607" ]

[]

sl

2015-08-27T20:02:21Z

false

true

5

GO:1990841

1,990,841

promoter-specific chromatin binding

molecular_function

Binding to a section of chromatin that is associated with gene promoter sequences of DNA.

[ "PMID:19948729" ]

null

[]

[ "GO:0003682" ]

[]

[ "GO:0003682" ]

[]

sl

2015-08-28T14:48:29Z

false

true

8

GO:1990842

1,990,842

obsolete response to prenatal stress

biological_process

OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis in the embryo or fetus during pregnancy.

[ "PMID:22738222" ]

This term was obsoleted at the TermGenie Gatekeeper stage.

[ "response to PNS" ]

[ "EXACT" ]

[]

sl

2015-08-31T15:15:29Z

true

8

GO:1990843

1,990,843

obsolete subsarcolemmal mitochondrion

cellular_component

OBSOLETE. A mitochondrion that occurs adjacent to the sarcolemma in striated muscle cells and responds in distinct ways to physiological triggers.

[ "PMID:23297307", "PMID:26039174" ]

This term was obsoleted because it corresponds to mitochondria of specific cell types and this information should be captured as an extension.

[ "SS mitochondrion", "SSM" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0005739" ]

[]

sl

2015-08-31T16:05:14Z

true

7

GO:1990844

1,990,844

obsolete interfibrillar mitochondrion

cellular_component

OBSOLETE. A mitochondrion that occurs in between fibrils of striated muscle cells and responds in distinct ways to physiological triggers.

[ "PMID:23297307", "PMID:26039174" ]

This term was obsoleted because it corresponds to mitochondria of specific cell types and this information should be captured as an extension.

[ "IFM", "IMF mitochondrion", "intermyofibrillar mitochondrion" ]

[ "EXACT", "EXACT", "EXACT" ]

[]

sl

2015-08-31T16:26:44Z

true

5

GO:1990845

1,990,845

adaptive thermogenesis

biological_process

The regulated production of heat in response to short term environmental changes, such as stress, diet or reduced temperature.

[ "PMID:17260010", "PMID:20363363" ]

null

[]

[ "Reactome:R-HSA-166187 \"Mitochondrial Uncoupling\"" ]

[ "GO:0001659" ]

[]

[ "GO:0001659" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31122\" xsd:anyURI" ]

sl

2015-08-31T18:19:49Z

false

true

2

GO:1990846

1,990,846

ribonucleoside-diphosphate reductase inhibitor activity

molecular_function

Binds to and stops, prevents or reduces the activity of ribonucleoside-diphosphate reductase.

[ "PMID:16317005" ]

null

[]

[ "GO:0004857" ]

[ "negatively_regulates GO:0061731" ]

[ "negatively_regulates" ]

[ "GO:0061731" ]

[ "GO:0004857", "GO:0061731" ]

[]

vw

2015-09-04T18:13:15Z

false

true

9

GO:1990847

1,990,847

obsolete peptide pheromone transmembrane export involved in positive regulation of conjugation with cellular fusion

biological_process

OBSOLETE. The directed movement of a peptide pheromone across a membrane and out of a cell by a secretion or export pathway used solely for the export of peptide pheromones that contributes to a conjugation process that results in the union of cellular and genetic information from compatible mating types.

[ "PMID:9236781" ]

This term was obsoleted because it represents a BP in a BP and should be captured with a GO-CAM model

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20310\" xsd:anyURI" ]

al

2015-09-08T15:23:26Z

true

1

GO:1990848

1,990,848

obsolete Positive regulation of removal of reactive oxygen species

biological_process

OBSOLETE. Any process that increases the frequency, rate or extent of removal of reactive oxygen species in a cell.

[ "PMID:24118096" ]

This term was obsoleted at the TermGenie Gatekeeper stage.

[]

al

2015-09-09T11:59:57Z

true

9

GO:1990849

1,990,849

vacuolar localization

biological_process

Any process in which the vacuole is transported to, and/or maintained in, a specific location within the cell.

[ "PMID:26283797" ]

null

[ "maintenance of vacuolar localization", "maintenance of vacuolar location", "maintenance of vacuole localization", "maintenance of vacuole location" ]

[ "EXACT", "NARROW", "EXACT", "EXACT" ]

[]

[ "GO:0051640" ]

[]

[ "GO:0051640" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22182\" xsd:anyURI" ]

mcc

2015-09-10T08:16:02Z

false

true

3

GO:1990850

1,990,850

H-gal-GP complex

cellular_component

A membrane glycoprotein complex with aspartyl proteinase and metalloproteinase activity which is expressed in the gut. An example of this is found in the nematode Haemonchus contortus.

[ "PMID:11166393" ]

null

[ "galactose-containing glycoprotein complex", "Haemonchus galactose-containing glycoprotein complex" ]

[ "NARROW", "EXACT" ]

[]

[ "GO:0098796", "GO:1905368" ]

[]

[ "GO:0098796", "GO:1905368" ]

[]

jl

2015-09-10T16:40:39Z

false

true

5