LiteFold/GO · Datasets at Hugging Face

GO:1990612

1,990,612

Sad1-Kms1 LINC complex

cellular_component

A LINC complex implicated in the connection of DNA double strand breaks to the cytoskeleton during DNA double-strand break repair.

[ "GOC:vw", "PMID:24943839", "PMID:24947240" ]

null

[]

[ "GO:0034993" ]

[]

[ "GO:0034993" ]

[]

jl

2015-01-20T13:10:49Z

false

true

2

GO:1990615

1,990,615

Kelch-containing formin regulatory complex

cellular_component

A protein complex that regulates actin cable formation, polarized cell growth, and cytokinesis in a formin-dependent manner. In S. cerevisiae the complex is composed of Bud14p and two Kelch family proteins, Kel1p and Kel2p.

[ "PMID:24828508" ]

null

[ "Bud14-Kel1-Kel2 complex", "KFRC complex" ]

[ "NARROW", "EXACT" ]

[]

[ "GO:0032991" ]

[]

[ "GO:0032991" ]

[]

mcc

2015-01-21T18:48:51Z

false

true

6

GO:1990616

1,990,616

magnesium ion export from mitochondrion

biological_process

The directed movement of magnesium ions out of mitochondrial matrix into the cytosol by means of some agent such as a transporter or pore.

[ "PMID:25585246" ]

null

[ "magnesium ion efflux from mitochondrion" ]

[ "EXACT" ]

[]

[ "GO:0010496", "GO:0045016" ]

[]

[ "GO:0010496", "GO:0045016" ]

[]

mcc

2015-01-21T22:06:42Z

false

true

6

GO:1990617

1,990,617

CHOP-ATF4 complex

cellular_component

A heterodimeric transcription factor complex that is composed of CHOP (C/EBP homology protein, GADD153) and ATF4 (activating transcription factor 4, also known as cAMP response element binding protein-2/CREB-2) subunits.

[ "GOC:bf", "GOC:PARL", "PMID:18940792" ]

null

[ "ATF4-CHOP heterodimer", "CHOP-ATF4 heterodimer", "CHOP-CREB-2 complex", "CHOP/ATF4 complex", "GADD153-ATF4 complex" ]

[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0090575" ]

[]

[ "GO:0090575" ]

[]

bf

2015-01-22T11:29:51Z

false

true

6

GO:1990618

1,990,618

obsolete ANPR-A:ANP complex

cellular_component

OBSOLETE. The ANPR-A:ANP complex is composed of the hormone AMP bound to the extracellular domain of ANPR-A domain. It is formed in the atrium in response to atrial distension (high blood volume) and leads to guanylate cyclase activity of the ANPR-A receptor, thereby elevating intracellular cGMP levels. The end result ...

[ "GOC:ame", "PMID:15117952" ]

An example of this is [ANPR-A:ANP] in [rat] (P18910:P01161-PRO_0000391785) in PMID:15117952 (inferred from direct assay).

[ "ANPR-A:ANP complex" ]

[ "EXACT" ]

[]

ame

2015-01-23T15:17:47Z

true

9

GO:1990619

1,990,619

obsolete histone H3-K9 deacetylation

biological_process

OBSOLETE. The modification of histone H3 by the removal of an acetyl group from lysine at position 9 of the histone.

[ "PMID:25002536" ]

This term was obsoleted because it represents a molecular function.

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24294\" xsd:anyURI" ]

al

2015-01-23T17:27:16Z

true

5

GO:1990620

1,990,620

ANPR-A receptor complex

cellular_component

A receptor complex composed of two ANPR-A molecules and expressed in the heart atrium in mammals; it plays a major role in the regulation of blood pressure and salt-fluid volume homeostasis. Binding of the ligand AMP in response to atrial distension (high blood volume) leads to guanylate cyclase activity of the ANPR-A ...

[ "GOC:ame", "PMID:15117952" ]

An example of this is Npr1 in rat (UniProt symbol P18910) in PMID:15117952 (inferred from direct assay).

[ "NPR1 receptor complex" ]

[ "RELATED" ]

[]

[ "GO:0043235" ]

[]

[ "GO:0043235" ]

[]

ame

2015-01-28T16:03:22Z

false

true

3

GO:1990621

1,990,621

ESCRT IV complex

cellular_component

An ESCRT complex that has AAA-ATPase activity and is involved in ESCRT-mediated intralumenal vesicle formation and the final stages of cytokinesis. The complex catalyzes disassembly of the ESCRT III filament around the neck of the budding vesicle in an ATP-driven reaction, resulting in membrane scission and recycling o...

[ "GOC:bhm", "GOC:ha", "PMID:20653365", "PMID:20696398", "PMID:21925211", "PMID:24456136", "PMID:25164817", "PMID:26775243" ]

null

[ "ESCRT-IV", "vacuolar protein sorting-associated complex", "Vps4 complex", "Vps4-Vta1 complex", "VPS4A-VPS4B", "VPS4A/B complex", "Vta1-Vps4 complex" ]

[ "EXACT", "RELATED", "RELATED", "NARROW", "NARROW", "NARROW", "RELATED" ]

[]

[ "GO:0036452", "GO:0098796", "GO:1904949" ]

[ "part_of GO:0010008" ]

[ "part_of" ]

[ "GO:0010008" ]

[ "GO:0010008", "GO:0036452", "GO:0098796", "GO:1904949" ]

[]

pr

2015-01-29T10:02:30Z

false

true

7

GO:1990622

1,990,622

CHOP-ATF3 complex

cellular_component

A heterodimeric protein complex that is composed of CHOP (C/EBP homology protein, GADD153) and ATF3 (activating transcription factor 3) subunits.

[ "GOC:bf", "GOC:PARL", "PMID:8622660" ]

null

[ "ATF3-CHOP complex", "CHOP-ATF3 heterodimer", "CHOP-ATF3 heterodimeric complex", "GADD153-ATF3 complex" ]

[ "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0005667", "GO:0140513" ]

[]

[ "GO:0005667", "GO:0140513" ]

[]

bf

2015-01-29T16:43:19Z

false

true

6

GO:1990623

1,990,623

Herring body

cellular_component

The dilated terminal portions of neurosecretory axons constituting the hypothalamohypophyseal tract, found in close proximity to sinusoidal capillaries in the posterior pituitary. Herring bodies consist of aggregates of membrane-bound neurosecretory vesicles where oxytocin or antidiuretic hormone (ADH) are stored prior...

[ "ISBN:0199652473", "Wikipedia:Herring_bodies" ]

null

[ "neurosecretory body" ]

[ "EXACT" ]

[]

[ "GO:0043679" ]

[]

[ "GO:0043679" ]

[]

cls

2015-01-29T21:11:54Z

false

true

5

GO:1990624

1,990,624

guanyl nucleotide exchange factor inhibitor activity

molecular_function

Binds to and stops, prevents or reduces the activity of a guanyl nucleotide exchange factor.

[ "GOC:vw", "PMID:25635048" ]

null

[]

[ "GO:0004857" ]

[]

[ "GO:0004857" ]

[]

vw

2015-01-31T15:17:01Z

false

true

9

GO:1990625

1,990,625

negative regulation of cytoplasmic translational initiation in response to stress

biological_process

Any process that stops, prevents or reduces the rate of cytoplasmic translation initiation as a result of a stimulus indicating the organism is under stress.

[ "GOC:vw", "PMID:12242291" ]

null

[]

[ "GO:0032055", "GO:0032057", "GO:1904689", "GO:1990611" ]

[]

[ "GO:0032055", "GO:0032057", "GO:1904689", "GO:1990611" ]

[ "GO:0065007", "negatively_regulates GO:0002183", "part_of GO:0033554" ]

[]

vw

2015-01-31T21:25:56Z

false

true

9

GO:1990626

1,990,626

mitochondrial outer membrane fusion

biological_process

The membrane organization process that joins two mitochondrial outer membranes to form a single membrane.

[ "GOC:vw", "PMID:21385840" ]

null

[ "mitochondrion outer membrane fusion" ]

[ "EXACT" ]

[]

[ "GO:0007008" ]

[ "part_of GO:0008053" ]

[ "part_of" ]

[ "GO:0008053" ]

[ "GO:0007008", "GO:0008053" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23133\" xsd:anyURI" ]

vw

2015-02-02T11:32:17Z

false

true

3

GO:1990627

1,990,627

mitochondrial inner membrane fusion

biological_process

The membrane organization process that joins two mitochondrial inner membranes to form a single membrane.

[ "GOC:vw", "PMID:17055438" ]

null

[ "mitochondrion inner membrane fusion" ]

[ "EXACT" ]

[]

[ "GO:0007007" ]

[ "part_of GO:0008053" ]

[ "part_of" ]

[ "GO:0008053" ]

[ "GO:0007007", "GO:0008053" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23133\" xsd:anyURI" ]

vw

2015-02-02T11:37:56Z

false

true

3

GO:1990629

1,990,629

phospholamban complex

cellular_component

A protein complex found as a homopentamer of the phospholamban (PLN) protein in the sarcoplasmic reticulum (SR) membrane of cardiomyocytes. Cardiac PLN is a main determinant of muscle contraction and relaxation, by regulating intracellular calcium levels.

[ "GOC:ame", "PMID:16043693" ]

An example of this is PLN in human (UniProt symbol P26678) in PMID:16043693 (inferred from direct assay).

[ "cardiac phospholamban complex", "cardiac PLB complex", "cardiac PLN complex" ]

[ "EXACT", "RELATED", "RELATED" ]

[]

[ "GO:0098796", "GO:0140534" ]

[ "part_of GO:0033017" ]

[ "part_of" ]

[ "GO:0033017" ]

[ "GO:0033017", "GO:0098796", "GO:0140534" ]

[]

ame

2015-02-05T14:12:36Z

false

true

2

GO:1990631

1,990,631

ErbB-4 class receptor binding

molecular_function

Binding to the protein-tyrosine kinase receptor ErbB-4/HER4.

[ "GOC:sl", "PMID:18523588" ]

null

[ "HER4 receptor binding" ]

[ "EXACT" ]

[]

[ "GO:0005102" ]

[]

[ "GO:0005102" ]

[]

sl

2015-02-06T23:28:49Z

false

true

8

GO:1990633

1,990,633

mutator focus

cellular_component

A type of punctate focus localized to the perinuclear region of germline cytoplasm in C. elegans. Mutator foci are required for RNA interference (RNAi) and serve as sites of small inhibitory RNA (siRNA) amplification. As such, proteins that localize to mutator foci include RNA-directed RNA polymerases (RdRPs) and beta-...

[ "GOC:kmv", "PMID:22713602", "PMID:25635455" ]

null

[]

[ "GO:0036464" ]

[ "part_of GO:0048471" ]

[ "part_of" ]

[ "GO:0048471" ]

[ "GO:0036464", "GO:0048471" ]

[]

kmv

2015-02-10T20:24:02Z

false

true

2

GO:1990634

1,990,634

protein phosphatase 5 binding

molecular_function

Binding to protein phosphatase 5.

[ "PMID:8943293" ]

null

[ "protein phosphatase T binding" ]

[ "EXACT" ]

[]

[ "GO:0019903" ]

[]

[ "GO:0019903" ]

[]

sl

2015-02-10T21:30:41Z

false

true

8

GO:1990637

1,990,637

response to prolactin

biological_process

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prolactin stimulus. The anterior pituitary hormone prolactin has a number of roles including being essential for lactation.

[ "PMID:7760850" ]

null

[]

[ "GO:0043434" ]

[]

[ "GO:0043434" ]

[]

sl

2015-02-10T23:47:11Z

false

true

6

GO:1990638

1,990,638

response to granulocyte colony-stimulating factor

biological_process

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte colony-stimulating factor stimulus.

[ "PMID:9488469" ]

null

[ "response to G-CSF" ]

[ "EXACT" ]

[]

[ "GO:0034097" ]

[]

[ "GO:0034097" ]

[]

sl

2015-02-11T00:02:33Z

false

true

1

GO:1990639

1,990,639

obsolete inositol-3,4,5-trisphosphate 5-phosphatase activity

molecular_function

OBSOLETE. Catalysis of the reaction: D-myo-inositol 3,4,5-trisphosphate + H2O = myo-inositol 3,4-bisphosphate + phosphate.

[ "PMID:11348594" ]

This term was obsoleted at the TermGenie Gatekeeper stage.

[ "inositol-3,4,5-trisphosphate 5-phosphatase activity" ]

[ "EXACT" ]

[]

al

2015-02-11T15:58:56Z

true

7

GO:1990640

1,990,640

inositol-2,4,5-triphosphate 5-phosphatase activity

molecular_function

Catalysis of the reaction: 1D-myo-inositol 2,4,5-trisphosphate + H2O = 1D-myo-inositol 2,4-bisphosphate + phosphate.

[ "PMID:15316017" ]

null

[]

[ "GO:0046030" ]

[]

[ "GO:0046030" ]

[]

al

2015-02-11T18:20:40Z

false

true

6

GO:1990641

1,990,641

response to iron ion starvation

biological_process

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of iron ion.

[ "PMID:16208485" ]

null

[]

[ "GO:0180055" ]

[]

[ "GO:0180055" ]

[]

sl

2015-02-11T18:43:28Z

false

true

2

GO:1990642

1,990,642

obsolete response to castration

biological_process

OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a castration stimulus, deprivation of gonads.

[ "PMID:11255226" ]

This term was obsoleted at the TermGenie Gatekeeper stage.

[ "response to castration" ]

[ "EXACT" ]

[]

sl

2015-02-11T18:53:04Z

true

9

GO:1990643

1,990,643

cellular response to granulocyte colony-stimulating factor

biological_process

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte colony-stimulating factor stimulus.

[ "PMID:9488469" ]

null

[]

[ "GO:0071345", "GO:1990638" ]

[]

[ "GO:0071345", "GO:1990638" ]

[]

sl

2015-02-11T19:22:44Z

false

true

7

GO:1990644

1,990,644

microtubule site clamp

molecular_function

The binding activity of a molecule that attaches the spindle microtubules to the kinetochore.

[ "PMID:20723757" ]

null

[]

[ "GO:0030674" ]

[]

[ "GO:0030674" ]

[]

vw

2015-02-13T15:50:13Z

false

true

7

GO:1990645

1,990,645

obsolete phosphorylase dephosphorylation

biological_process

OBSOLETE. The modification of phosphorylases by removal of phosphate groups.

[ "PMID:8602837" ]

This term was obsoleted at the TermGenie Gatekeeper stage.

[ "phosphorylase dephosphorylation" ]

[ "EXACT" ]

[]

sl

2015-02-18T16:39:50Z

true

7

GO:1990646

1,990,646

cellular response to prolactin

biological_process

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prolactin stimulus.

[ "PMID:7760850" ]

null

[]

[ "GO:0071375", "GO:1990637" ]

[]

[ "GO:0071375", "GO:1990637" ]

[]

sl

2015-02-18T16:53:11Z

false

true

3

GO:1990647

1,990,647

C/EBP complex

cellular_component

A dimeric, sequence specific DNA-binding transcription factor complex regulating the expression of genes involved in immune and inflammatory responses. Exists at least as alpha and beta homodimeric forms. Binds to regulatory regions of several acute-phase and cytokines genes and probably plays a role in the regulation ...

[ "GOC:bhm", "GOC:pad", "GOC:PARL", "PMID:8657121" ]

An example of this is Cebpa in rat (P05554) in PMID:8657121 (inferred from direct assay).

[ "C/EBP homodimer complex", "C/EBP transcription factor complex", "C/EBPalpha complex", "C/EBPalpha homodimer complex", "C/EBPbeta complex", "C/EBPbeta homodimer complex" ]

[ "EXACT", "EXACT", "NARROW", "NARROW", "NARROW", "NARROW" ]

[]

[ "GO:0090575" ]

[]

[ "GO:0090575" ]

[]

bhm

2015-02-19T11:00:09Z

false

true

3

GO:1990648

1,990,648

inositol-4,5,6-triphosphate 5-phosphatase activity

molecular_function

Catalysis of the reaction: 1D-myo-inositol 4,5,6-trisphosphate + H2O = 1D-myo-inositol 4,6-bisphosphate + phosphate.

[ "GOC:al", "PMID:15316017" ]

null

[]

[ "GO:0046030" ]

[]

[ "GO:0046030" ]

[]

al

2015-02-23T11:10:51Z

false

true

9

GO:1990649

1,990,649

inositol-1,2,4,5-tetrakisphosphate 5-phosphatase activity

molecular_function

Catalysis of the reaction: 1D-myo-inositol 1,2,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,2,4-trisphosphate + phosphate.

[ "GOC:al", "PMID:15316017" ]

null

[]

[ "GO:0052743" ]

[]

[ "GO:0052743" ]

[]

al

2015-02-23T11:12:10Z

false

true

7

GO:1990650

1,990,650

inositol-2,4,5,6-tetrakisphosphate 5-phosphatase activity

molecular_function

Catalysis of the reaction: 1D-myo-inositol 2,4,5,6-tetrakisphosphate + H2O = 1D-myo-inositol 2,4,6-trisphosphate + phosphate.

[ "GOC:al", "PMID:15316017" ]

null

[]

[ "GO:0052743" ]

[]

[ "GO:0052743" ]

[]

al

2015-02-23T11:14:17Z

false

true

3

GO:1990651

1,990,651

inositol-1,2,4,5,6-pentakisphosphate 5-phosphatase activity

molecular_function

Catalysis of the reaction: 1D-myo-inositol 1,2,4,5,6-pentakisphosphate + H2O = 1D-myo-inositol 1,2,4,6-tetrakisphosphate + phosphate.

[ "GOC:al", "PMID:15316017" ]

null

[]

[ "GO:0052827" ]

[]

[ "GO:0052827" ]

[]

al

2015-02-23T11:17:19Z

false

true

4

GO:1990652

1,990,652

obsolete positive regulation of pyrimidine-containing compound salvage by positive regulation of transcription from RNA polymerase II promoter

biological_process

OBSOLETE. A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of pyrimidine-containing compound salvage.

[ "PMID:23695302" ]

This term was obsoleted at the TermGenie Gatekeeper stage.

[ "positive regulation of pyrimidine-containing compound salvage by positive regulation of transcription from RNA polymerase II promoter" ]

[ "EXACT" ]

[]

al

2015-02-23T11:25:51Z

true

2

GO:1990653

1,990,653

obsolete monounsaturated fatty acid biosynthetic process

biological_process

OBSOLETE. The chemical reactions and pathways resulting in the formation of a monounsaturated fatty acid. A monounsaturated fatty acid has one double bond in the fatty acid chain with all of the remainder carbon atoms being single-bonded, as opposed to polyunsaturated fatty acids.

[ "GOC:hjd", "PMID:16443825" ]

For example, stearoyl-coenzyme A desaturase (Scd) catalyzes the desaturation of saturated fatty acids to monounsaturated fatty acids in mammals and yeast.

[]

hjd

2015-02-23T18:59:15Z

true

4

GO:1990654

1,990,654

sebum secreting cell proliferation

biological_process

The multiplication or reproduction of sebocytes by cell division, resulting in the expansion of their population. A sebocyte is an epithelial cell that makes up the sebaceous glands, and secrete sebum.

[ "GOC:hjd", "PMID:16901790", "PMID:18474083" ]

null

[ "sebocyte proliferation" ]

[ "RELATED" ]

[]

[ "GO:0050673" ]

[]

[ "GO:0050673" ]

[]

hjd

2015-02-23T19:43:49Z

false

true

5

GO:1990655

1,990,655

4 iron, 3 sulfur cluster binding

molecular_function

Binding to a 4 iron, 3 sulfur (4Fe-3S) cluster, an uncommon iron-sulfur cluster with unique properties found in oxygen-tolerant Ni-Fe hydrogenases of various bacteria.

[ "GOC:am", "PMID:23267108" ]

null

[ "4Fe-3S cluster binding" ]

[ "RELATED" ]

[]

[ "GO:0051536" ]

[]

[ "GO:0051536" ]

[]

pr

2015-02-24T17:07:23Z

false

true

3

GO:1990656

1,990,656

t-SNARE clustering

biological_process

The clustering process in which t-SNARES are localized to distinct domains in the cell membrane. t-SNAREs are cell surface proteins which are part of secretory microdomain assemblies.

[ "PMID:22528485" ]

null

[]

[ "GO:0072657" ]

[]

[ "GO:0072657" ]

[]

sl

2015-02-25T00:18:33Z

false

true

4

GO:1990657

1,990,657

iNOS-S100A8/A9 complex

cellular_component

A protein complex capable of stimulus-inducible nitric-oxide synthase activity. S-nitrosylates cysteine residues in target proteins, a principal mechanism of nitric oxide (NO)-mediated signal transduction. In mammals consists of NOS2, S100A8 and S100A9. S100A9 acts both as an adaptor linking NOS2 to its target and as a...

[ "GOC:bhm", "PMID:25417112" ]

An example of this is NOS2 in human (UniProt symbol P35228) in PMID:25417112 (inferred from direct assay).

[]

[ "GO:1903958", "GO:1990658" ]

[]

[ "GO:1903958", "GO:1990658" ]

[]

bhm

2015-02-25T11:00:49Z

false

true

3

GO:1990658

1,990,658

transnitrosylase complex

cellular_component

A transferase complex which is capable of transferring nitrogenous groups from one component to another.

[ "GOC:bhm", "PMID:25417112" ]

An example of this is S100A9 in human (UniProt symbol P06702) in PMID:25417112 (inferred from direct assay).

[ "transferase complex, transferring nitrogenous groups" ]

[ "EXACT" ]

[]

[ "GO:1990234" ]

[ "part_of GO:0005737" ]

[ "part_of" ]

[ "GO:0005737" ]

[ "GO:0005737", "GO:1990234" ]

[]

bhm

2015-02-25T11:17:17Z

false

true

9

GO:1990659

1,990,659

obsolete sequestering of manganese ion

biological_process

OBSOLETE. The process of binding or confining manganese ions such that they are separated from other components of a biological system.

[ "GOC:bhm", "PMID:25417112" ]

The reason for obsoletion is that this represents a molecular function, not a biological process.

[ "manganese ion retention", "manganese ion sequestering", "manganese ion sequestration", "manganese ion storage", "retention of manganese ion", "sequestration of manganese ion", "storage of manganese ion" ]

[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0140487" ]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/17075\" xsd:anyURI" ]

bhm

2015-02-25T11:41:12Z

true

5

GO:1990660

1,990,660

calprotectin complex

cellular_component

A protein complex composed of S100A8 and S100A9 and capable of limiting Mn(2+) and Zn(2+) availability at sites of infection. Also binds Ca(2+). Expressed and released by neutrophils and epithelial cells, it exhibits broad-spectrum antimicrobial activity attributed to its metal-binding properties. Endogenous ligand of ...

[ "GOC:bhm", "PMID:25417112" ]

An example of this is S100A9 in human (UniProt symbol P06702) in PMID:25417112 (inferred from direct assay).

[ "calprotectin heterodimer" ]

[ "NARROW" ]

[]

[ "GO:0032991" ]

[]

[ "GO:0032991" ]

[]

bhm

2015-02-25T14:03:17Z

false

true

8

GO:1990661

1,990,661

S100A8 complex

cellular_component

A protein complex composed of a S100A8 dimer and capable of binding to toll-like receptor 4 (TLR4).

[ "GOC:bhm", "PMID:25417112" ]

An example of this is S100A8 in human (UniProt symbol P27005) in PMID:25417112 (inferred from direct assay).

[ "S100A8 homodimer" ]

[ "EXACT" ]

[]

[ "GO:0032991" ]

[]

[ "GO:0032991" ]

[]

bhm

2015-02-25T15:33:32Z

false

true

1

GO:1990662

1,990,662

S100A9 complex

cellular_component

A protein complex composed of a S100A9 dimer and capable of binding to toll-like receptor 4 (TLR4) and the receptor for advanced glycation end products (RAGE) initiating signal transduction through NF-kappa-B pathways. Transports arachidonic acid between the cytosol and the NADPH oxidase complex at the plasma membrane ...

[ "GOC:bhm", "PMID:15642721" ]

An example of this is S100A9 in human (UniProt symbol P06702) in PMID:15642721 (inferred from direct assay).

[ "S100A9 homodimer" ]

[ "EXACT" ]

[]

[ "GO:1902495" ]

[]

[ "GO:1902495" ]

[]

bhm

2015-02-25T15:55:48Z

false

true

1

GO:1990663

1,990,663

dihydroorotate dehydrogenase (fumarate) activity

molecular_function

Catalysis of the reaction: (S)-dihydroorotate + fumarate = orotate + succinate.

[ "PMID:1409592", "RHEA:30059" ]

null

[]

[ "EC:1.3.98.1", "RHEA:30059" ]

[ "GO:0004152" ]

[]

[ "GO:0004152" ]

[]

[ "skos:exactMatch EC:1.3.98.1", "skos:exactMatch RHEA:30059", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]

al

2015-02-26T15:47:30Z

false

true

5

GO:1990664

1,990,664

Nkx-2.5 complex

cellular_component

A transcription factor complex formed by two or more subunits of Nkx-2.5. Nkx-2.5 is an evolutionary conserved transcription factor important for the specification and differentiation of cardiomyocytes during heart development. It is also required for spleen development. It binds DNA either as a monomer, or a homodimer...

[ "GOC:ame", "PMID:22849347" ]

An example of this is Nkx-2.5 in human (UniProt symbol P52952) in PMID:22849347 (inferred from direct assay).

[ "Nkx-2.5 homodimer complex", "NKX.2-5 homodimer complex", "NKX2.5 complex", "NKX2E homodimer complex" ]

[ "NARROW", "RELATED", "RELATED", "RELATED" ]

[]

[ "GO:0090575" ]

[]

[ "GO:0090575" ]

[]

ame

2015-02-27T12:22:06Z

false

true

1

GO:1990665

1,990,665

AnxA2-p11 complex

cellular_component

A heterotetrameric protein complex comprising two Annexin A2 (AnxA2) monomers and two copies of its binding partner, S100 protein p11 (S100A10).

[ "GOC:bf", "GOC:BHF", "GOC:nc", "PMID:18799458", "PMID:23483454" ]

null

[ "(A2.p11)2 complex", "(p11)2.(AnxA2)2 complex", "Annexin A2 tetramer", "Annexin A2-p11 complex", "AnxA2.p11 complex", "AnxA2:S100A10 heterotetramer" ]

[ "EXACT", "EXACT", "RELATED", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0032991" ]

[]

[ "GO:0032991" ]

[]

bf

2015-03-02T10:07:42Z

false

true

3

GO:1990668

1,990,668

vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane

biological_process

The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane of the ERGIC. This can involve anterograde or retrograde transport vesicles.

[ "GOC:bhm", "PMID:16038056", "PMID:24119662" ]

null

[ "vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment membrane", "vesicle fusion with ER-Golgi intermediate compartment (ERGIC) membrane", "vesicle fusion with ER-Golgi intermediate compartment membrane", "vesicle fusion with ERGIC membrane" ]

[ "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0006906" ]

[]

[ "GO:0006906" ]

[]

bhm

2015-03-02T11:17:32Z

false

true

5

GO:1990669

1,990,669

endoplasmic reticulum-Golgi intermediate compartment (ERGIC) derived vesicle fusion with endoplasmic reticulum membrane

biological_process

The joining of the lipid bilayer membrane around an ERGIC-derived vesicle to the lipid bilayer membrane of the ER. Such vesicles include COPI-coated transport vesicles involved in retrograde transport.

[ "GOC:bhm", "PMID:16038056", "PMID:24119662" ]

null

[ "endoplasmic reticulum-Golgi intermediate compartment (ERGIC) derived vesicle fusion with ER membrane", "ER-Golgi intermediate compartment derived vesicle fusion with ER membrane" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0048279" ]

[ "part_of GO:0006890" ]

[ "part_of" ]

[ "GO:0006890" ]

[ "GO:0006890", "GO:0048279" ]

[]

bhm

2015-03-02T11:21:43Z

false

true

6

GO:1990670

1,990,670

vesicle fusion with Golgi cis cisterna membrane

biological_process

The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi cis cisterna. This can involve anterograde or retrograde transport vesicles.

[ "GOC:bhm", "PMID:16038056", "PMID:24119662" ]

null

[]

[ "GO:0006906" ]

[]

[ "GO:0006906" ]

[]

bhm

2015-03-02T11:25:19Z

false

true

9

GO:1990672

1,990,672

medial-Golgi-derived vesicle fusion with Golgi trans cisterna membrane

biological_process

The joining of the lipid bilayer membrane around a medial-Golgi-derived vesicle to the lipid bilayer membrane around the Golgi trans cisterna. Vesicles are involved in anterograde transport.

[ "GOC:bhm", "PMID:16038056", "PMID:24119662" ]

null

[]

[ "GO:0048210", "GO:0048280" ]

[ "part_of GO:0048219" ]

[ "part_of" ]

[ "GO:0048219" ]

[ "GO:0048210", "GO:0048219", "GO:0048280" ]

[]

bhm

2015-03-02T11:34:39Z

false

true

2

GO:1990673

1,990,673

obsolete intrinsic component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane

cellular_component

OBSOLETE. The component of the ERGIC membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.

[ "GOC:bhm", "PMID:16038056", "PMID:24119662" ]

This term was obsoleted because it represents protein topology, not a cellular component.

[ "intrinsic component of endoplasmic reticulum-Golgi intermediate compartment membrane" ]

[ "EXACT" ]

[]

[ "GO:0033116" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23424\" xsd:anyURI" ]

bhm

2015-03-02T11:44:46Z

true

5

GO:1990674

1,990,674

Golgi cis cisterna membrane

cellular_component

The lipid bilayer surrounding any of the thin, flattened compartments that form the cis portion of the Golgi complex.

[ "GOC:bhm", "PMID:16038056", "PMID:24119662" ]

null

[ "cis-Golgi cisterna membrane", "Golgi apparatus cis cisterna membrane" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0032580" ]

[ "part_of GO:0000137" ]

[ "part_of" ]

[ "GO:0000137" ]

[ "GO:0000137", "GO:0032580" ]

[]

bhm

2015-03-02T11:48:00Z

false

true

2

GO:1990675

1,990,675

Golgi medial cisterna membrane

cellular_component

The lipid bilayer surrounding any of the thin, flattened compartments that form the medial portion of the Golgi complex.

[ "GOC:bhm", "PMID:16038056", "PMID:24119662" ]

null

[ "Golgi apparatus medial cisterna membrane", "medial-Golgi cisterna membrane" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0032580" ]

[ "part_of GO:0005797" ]

[ "part_of" ]

[ "GO:0005797" ]

[ "GO:0005797", "GO:0032580" ]

[]

bhm

2015-03-02T11:50:29Z

false

true

7

GO:1990676

1,990,676

Golgi trans cisterna membrane

cellular_component

The lipid bilayer surrounding any of the thin, flattened compartments that form the trans portion of the Golgi complex.

[ "GOC:bhm", "PMID:16038056", "PMID:24119662" ]

null

[ "trans-Golgi cisterna membrane" ]

[ "EXACT" ]

[]

[ "GO:0032580" ]

[ "part_of GO:0000138" ]

[ "part_of" ]

[ "GO:0000138" ]

[ "GO:0000138", "GO:0032580" ]

[]

bhm

2015-03-02T11:53:35Z

false

true

7

GO:1990677

1,990,677

mitochondrial inner membrane assembly complex

cellular_component

A protein complex that promotes the biogenesis of mitochondrial F1Fo-ATP synthase by facilitating assembly of the peripheral stalk. Loss of INAC function causes dissociation of the F1-domain from the membrane-integral Fo-portion.

[ "GOC:bhm", "PMID:24942160" ]

An example of this is INA22 in Saccharomyces cerevisiae (P40576) in PMID:24942160 (inferred from direct assay/mutant phenotype/etc.).

[ "INAC complex", "inner membrane assembly complex", "mitochondrion inner membrane assembly complex" ]

[ "EXACT", "BROAD", "EXACT" ]

[]

[ "GO:0098800" ]

[]

[ "GO:0098800" ]

[]

bhm

2015-03-02T13:14:52Z

false

true

2

GO:1990678

1,990,678

obsolete histone H4-K16 deacetylation

biological_process

OBSOLETE. The modification of histone H4 by the removal of an acetyl group from lysine at position 16 of the histone.

[ "PMID:17446861" ]

This term was obsoleted because it represents a molecular function.

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24294\" xsd:anyURI" ]

al

2015-03-02T15:25:56Z

true

6

GO:1990679

1,990,679

obsolete histone H4-K12 deacetylation

biological_process

OBSOLETE. The modification of histone H4 by the removal of an acetyl group from lysine at position 12 of the histone.

[ "PMID:17446861" ]

This term was obsoleted because it represents a molecular function.

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24294\" xsd:anyURI" ]

al

2015-03-02T15:40:44Z

true

5

GO:1990680

1,990,680

response to melanocyte-stimulating hormone

biological_process

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a melanocyte-stimulating hormone stimulus. The binding of any one of three melanocyte-stimulating hormones causes dispersal of melanosomes in mela...

[ "PMID:17036007" ]

null

[ "response to MSH" ]

[ "EXACT" ]

[]

[ "GO:0043434" ]

[]

[ "GO:0043434" ]

[]

sl

2015-03-02T20:49:46Z

false

true

4

GO:1990682

1,990,682

CSF1-CSF1R complex

cellular_component

A protein complex consisting of a macrophage colony-stimulating factor (CSF1, also called M-CSF) dimer bound to a dimerized receptor (CSF1R, also called FMS). Receptor dimerization requires the presence of the ligand.

[ "GOC:bf", "GOC:BHF", "GOC:nc", "PMID:19017797" ]

null

[ "CSF1:C-FMS complex", "M-CSF:C-FMS complex", "M-CSF:CSF1R complex", "M-CSF:FMS complex", "macrophage colony-stimulating factor:receptor complex" ]

[ "EXACT", "RELATED", "RELATED", "EXACT", "EXACT" ]

[]

[ "GO:0032991" ]

[]

[ "GO:0032991" ]

[]

bf

2015-03-10T12:23:03Z

false

true

2

GO:1990683

1,990,683

DNA double-strand break attachment to nuclear envelope

biological_process

A process in which the DNA double-strand breaks are attached to the inner surface of the nuclear envelope proximal to the spindle pole body, or iMTOCs.

[ "PMID:24943839" ]

null

[]

[ "GO:0097240" ]

[]

[ "GO:0097240" ]

[]

vw

2015-03-10T16:36:21Z

false

true

8

GO:1990684

1,990,684

protein-lipid-RNA complex

cellular_component

A macromolecular complex containing separate protein, lipid and RNA molecules. Separate in this context means not covalently bound to each other.

[ "GOC:vesicles", "PMID:21423178", "PMID:22028337", "PMID:23559634" ]

Examples of protein-lipid-RNA complexes are described in PMID:21423178 and PMID:23559634, both showing evidence that high-density lipoprotein (HDL) and, to a lesser extent, low-density lipoprotein (HDL) transport endogenous microRNAs (miRNAs) and deliver them to recipient cells with functional targeting capabilities. A...

[ "miRNA-lipoprotein complex" ]

[ "RELATED" ]

[]

[ "GO:0032991" ]

[]

[ "GO:0032991" ]

[]

pr

2015-03-11T14:24:33Z

false

true

8

GO:1990685

1,990,685

HDL-containing protein-lipid-RNA complex

cellular_component

A protein-lipid-RNA complex containing separate high-density lipoprotein (HDL), lipid and RNA molecules. Separate in this context means not covalently bound to each other.

[ "GOC:vesicles", "PMID:21423178", "PMID:23559634" ]

Examples of HDL-containing protein-lipid-RNA complexes are described in PMID:21423178 and PMID:23559634, both showing evidence that high-density lipoproteins (HDL) transport endogenous microRNAs (miRNAs) and deliver them to recipient cells with functional targeting capabilities. Also see fig. 1 in the review PMID:22028...

[]

[ "GO:1990684" ]

[]

[ "GO:1990684" ]

[]

pr

2015-03-11T14:56:52Z

false

true

9

GO:1990686

1,990,686

LDL-containing protein-lipid-RNA complex

cellular_component

A protein-lipid-RNA complex containing separate low-density lipoprotein (LDL), lipid and RNA molecules. Separate in this context means not covalently bound to each other.

[ "GOC:vesicles", "PMID:23559634" ]

Examples of LDL-containing protein-lipid-RNA complexes are described in PMID:21423178 and PMID:23559634, both showing evidence that high-density lipoprotein (HDL) and, to a lesser extent, low-density lipoprotein (HDL) transport endogenous microRNAs (miRNAs) and deliver them to recipient cells with functional targeting ...

[]

[ "GO:1990684" ]

[]

[ "GO:1990684" ]

[]

pr

2015-03-11T15:11:34Z

false

true

9

GO:1990687

1,990,687

endoplasmic reticulum-derived vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane

biological_process

The joining of the lipid bilayer membrane around an endoplasmic reticulum-derived vesicle to the lipid bilayer membrane of the ERGIC. Such vesicles include COPII-coated transport vesicles involved in anterograde transport.

[ "GOC:bhm", "PMID:16038056", "PMID:24119662" ]

null

[ "ER-derived vesicle fusion with ER-Golgi intermediate compartment membrane", "ER-derived vesicle fusion with ERGIC membrane" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:1990668" ]

[ "part_of GO:0006888" ]

[ "part_of" ]

[ "GO:0006888" ]

[ "GO:0006888", "GO:1990668" ]

[]

bhm

2015-03-12T09:31:45Z

false

true

3

GO:1990688

1,990,688

Golgi vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane

biological_process

The joining of the lipid bilayer membrane around a Golgi vesicle to the lipid bilayer membrane of the ERGIC. Such vesicles include COPI-coated transport vesicles involved in retrograde transport.

[ "GOC:bhm", "PMID:16038056", "PMID:24119662" ]

null

[ "Golgi vesicle fusion with ER-Golgi intermediate compartment membrane", "Golgi vesicle fusion with ERGIC membrane" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:1990668" ]

[ "part_of GO:0006890" ]

[ "part_of" ]

[ "GO:0006890" ]

[ "GO:0006890", "GO:1990668" ]

[]

bhm

2015-03-12T09:34:21Z

false

true

4

GO:1990689

1,990,689

endoplasmic reticulum-Golgi intermediate compartment (ERGIC) derived vesicle fusion with Golgi cis cisterna membrane

biological_process

The joining of the lipid bilayer membrane around an ERGIC-derived vesicle to the lipid bilayer membrane around the Golgi cis cisterna. Such vesicles include COPII-coated transport vesicles involved in anterograde transport.

[ "GOC:bhm", "PMID:16038056", "PMID:24119662" ]

null

[ "endoplasmic reticulum-Golgi intermediate compartment (ERGIC) derived vesicle fusion with cis-Golgi cisterna membrane", "ER-Golgi intermediate compartment derived vesicle fusion with cis-Golgi cisterna membrane", "ER-Golgi intermediate compartment derived vesicle fusion with Golgi cis cisterna membrane", "ERG...

[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0048280", "GO:1990670" ]

[ "part_of GO:0006888" ]

[ "part_of" ]

[ "GO:0006888" ]

[ "GO:0006888", "GO:0048280", "GO:1990670" ]

[]

bhm

2015-03-12T09:41:48Z

false

true

4

GO:1990690

1,990,690

Golgi medial cisterna-derived vesicle fusion with Golgi cis cisterna membrane

biological_process

The joining of the lipid bilayer membrane around a Golgi medial cisterna-derived vesicle to the lipid bilayer membrane around the Golgi cis cisterna. Such vesicles include COPI-coated transport vesicles involved in retrograde transport.

[ "GOC:bhm", "PMID:16038056", "PMID:24119662" ]

null

[ "Golgi apparatus medial cisterna-derived vesicle fusion with Golgi apparatus cis cisterna membrane", "medial-Golgi cisterna-derived vesicle fusion with cis-Golgi cisterna membrane" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0048210", "GO:0048280" ]

[ "part_of GO:0000301" ]

[ "part_of" ]

[ "GO:0000301" ]

[ "GO:0000301", "GO:0048210", "GO:0048280" ]

[]

bhm

2015-03-12T09:47:03Z

false

true

8

GO:1990691

1,990,691

cis-Golgi-derived vesicle fusion with Golgi medial cisterna membrane

biological_process

The joining of the lipid bilayer membrane around a cis-Golgi-derived vesicle to the lipid bilayer membrane around the medial-Golgi cisterna. Vesicles are involved in anterograde transport.

[ "GOC:bhm", "PMID:16038056", "PMID:24119662" ]

null

[ "cis-Golgi-derived vesicle fusion with medial-Golgi cisterna membrane" ]

[ "EXACT" ]

[]

[ "GO:0048210", "GO:0048280" ]

[ "part_of GO:0048219" ]

[ "part_of" ]

[ "GO:0048219" ]

[ "GO:0048210", "GO:0048219", "GO:0048280" ]

[]

bhm

2015-03-12T09:51:01Z

false

true

2

GO:1990692

1,990,692

trans-Golgi-derived vesicle fusion with Golgi medial cisterna membrane

biological_process

The joining of the lipid bilayer membrane around a trans-Golgi-derived vesicle to the lipid bilayer membrane around the medial-Golgi cisterna. Such vesicles include COPI-coated transport vesicles involved in retrograde transport.

[ "GOC:bhm", "PMID:16038056", "PMID:24119662" ]

null

[ "trans-Golgi-derived vesicle fusion with medial-Golgi cisterna membrane" ]

[ "EXACT" ]

[]

[ "GO:0048210", "GO:0048280" ]

[ "part_of GO:0000301" ]

[ "part_of" ]

[ "GO:0000301" ]

[ "GO:0000301", "GO:0048210", "GO:0048280" ]

[]

bhm

2015-03-12T09:54:02Z

false

true

6

GO:1990693

1,990,693

obsolete intrinsic component of Golgi cis cisterna membrane

cellular_component

OBSOLETE. The component of the Golgi cis cisterna membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.

[ "GOC:bhm", "PMID:16038056", "PMID:24119662" ]

This term was obsoleted because it represents protein topology, not a cellular component.

[ "intrinsic component of cis-Golgi cisterna membrane" ]

[ "EXACT" ]

[]

[ "GO:1990674" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23424\" xsd:anyURI" ]

bhm

2015-03-12T10:24:07Z

true

6

GO:1990694

1,990,694

obsolete intrinsic component of Golgi medial cisterna membrane

cellular_component

OBSOLETE. The component of the Golgi medial cisterna membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.

[ "GOC:bhm", "PMID:16038056", "PMID:24119662" ]

This term was obsoleted because it represents protein topology, not a cellular component.

[ "intrinsic component of medial-Golgi cisterna membrane" ]

[ "EXACT" ]

[]

[ "GO:1990675" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23424\" xsd:anyURI" ]

bhm

2015-03-12T10:29:12Z

true

6

GO:1990695

1,990,695

obsolete intrinsic component of Golgi trans cisterna membrane

cellular_component

OBSOLETE. The component of the Golgi trans cisterna membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.

[ "GOC:bhm", "PMID:16038056", "PMID:24119662" ]

This term was obsoleted because it represents protein topology, not a cellular component.

[ "intrinsic component of trans-Golgi cisterna membrane" ]

[ "EXACT" ]

[]

[ "GO:1990676" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23424\" xsd:anyURI" ]

bhm

2015-03-12T10:36:02Z

true

5

GO:1990696

1,990,696

USH2 complex

cellular_component

A protein complex composed of four proteins, loss of which results in Usher Syndrome type 2 (USH2 syndrome), a leading genetic cause of combined hearing and vision loss. This complex is conserved in many species; in mice, it is composed of USH2A, GPR98 (aka ADGRV1), WHRN, and PDZD7.

[ "GOC:krc", "PMID:25406310" ]

null

[ "USH2 quaternary protein complex" ]

[ "EXACT" ]

[]

[ "GO:0032991" ]

[]

[ "GO:0032991" ]

[]

krc

2015-03-12T17:29:18Z

false

true

7

GO:1990698

1,990,698

palmitoleoyltransferase activity

molecular_function

Catalysis of the transfer of a palmitoleoyl group, a 16-carbon monounsaturated fatty acid (C16:1), to an acceptor molecule.

[ "PMID:17141155", "PMID:25731175" ]

Note that this term should not be confused with 'palmitoyltransferase activity ; GO:0016409'.

[]

[ "EC:2.3.1.250", "RHEA:45336" ]

[ "GO:0016747" ]

[]

[ "GO:0016747" ]

[]

[ "skos:narrowMatch EC:2.3.1.250", "skos:narrowMatch RHEA:45336", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27365\" xsd:anyURI" ]

sp

2015-03-13T08:58:25Z

false

true

1

GO:1990699

1,990,699

palmitoleyl hydrolase activity

molecular_function

Catalysis of a hydrolase reaction that removes a palmitoleyl moiety, a 16-carbon monounsaturated fatty acid (C16:1), from some substrate.

[ "PMID:25731175" ]

null

[]

[ "EC:3.1.1.98", "RHEA:45340" ]

[ "GO:0052689" ]

[]

[ "GO:0052689" ]

[]

[ "skos:narrowMatch EC:3.1.1.98", "skos:narrowMatch RHEA:45340", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24890\" xsd:anyURI" ]

sp

2015-03-13T09:00:05Z

false

true

1

GO:1990700

1,990,700

nucleolar chromatin organization

biological_process

Any process that results in the specification, formation or maintenance of the physical structure of nucleolar chromatin.

[ "PMID:18362178" ]

null

[ "establishment or maintenance of nucleolar chromatin architecture", "nucleolar chromatin organisation" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0006325" ]

[ "part_of GO:0007000" ]

[ "part_of" ]

[ "GO:0007000" ]

[ "GO:0006325", "GO:0007000" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31276\" xsd:anyURI" ]

mah

2015-03-16T12:11:01Z

false

true

3

GO:1990701

1,990,701

obsolete integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane

cellular_component

OBSOLETE. The component of the ERGIC membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

[ "GOC:bhm", "PMID:16038056", "PMID:24119662" ]

This term was obsoleted because it represents protein topology, not a cellular component.

[ "integral component of endoplasmic reticulum-Golgi intermediate compartment membrane", "integral component of ER-Golgi intermediate compartment membrane", "integral component of ERGIC membrane" ]

[ "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0033116" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23424\" xsd:anyURI" ]

bhm

2015-03-16T15:57:36Z

true

9

GO:1990702

1,990,702

obsolete integral component of Golgi cis cisterna membrane

cellular_component

OBSOLETE. The component of the Golgi cis membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

[ "GOC:bhm", "PMID:16038056", "PMID:24119662" ]

This term was obsoleted because it represents protein topology, not a cellular component.

[ "integral component of cis-Golgi cisterna membrane" ]

[ "EXACT" ]

[]

[ "GO:1990674" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23424\" xsd:anyURI" ]

bhm

2015-03-16T16:03:21Z

true

2

GO:1990704

1,990,704

obsolete integral component of Golgi trans cisterna membrane

cellular_component

OBSOLETE. The component of the Golgi trans membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

[ "GOC:bhm", "PMID:16038056", "PMID:24119662" ]

This term was obsoleted because it represents protein topology, not a cellular component.

[ "integral component of trans-Golgi cisterna membrane" ]

[ "EXACT" ]

[]

[ "GO:1990676" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23424\" xsd:anyURI" ]

bhm

2015-03-16T16:08:07Z

true

7

GO:1990705

1,990,705

cholangiocyte proliferation

biological_process

The multiplication or reproduction of cholangiocytes, resulting in the expansion of the cholangiocyte population. A cholangiocyte is an epithelial cell that is part of the bile duct. Cholangiocytes contribute to bile secretion via net release of bicarbonate and water.

[ "PMID:24434010" ]

null

[ "hepatoblast proliferation" ]

[ "EXACT" ]

[]

[ "GO:0050673" ]

[]

[ "GO:0050673" ]

[]

null

2015-03-16T23:23:50Z

false

true

5

GO:1990708

1,990,708

conditioned place preference

biological_process

The associative learning process by which an animal learns and remembers an association between a neutral, unchanging environment and a putatively rewarding, internal state produced by a xenobiotic or drug.

[ "PMID:21549821" ]

null

[]

[ "GO:0008306" ]

[]

[ "GO:0008306" ]

[]

sl

2015-03-18T20:28:59Z

false

true

4

GO:1990709

1,990,709

presynaptic active zone organization

biological_process

A process that results in the assembly, arrangement of constituent parts, or disassembly of a presynaptic active zone.

[ "GOC:pr", "PMID:16865347", "PMID:17068967" ]

null

[ "presynaptic active zone organisation" ]

[ "EXACT" ]

[]

[ "GO:0016043" ]

[ "part_of GO:0050808" ]

[ "part_of" ]

[ "GO:0050808" ]

[ "GO:0016043", "GO:0050808" ]

[]

pr

2015-03-20T10:16:24Z

false

true

3

GO:1990710

1,990,710

MutS complex

cellular_component

A homodimeric mismatch repair complex involved in binding to and correcting insertion/deletion mutations.

[ "GOC:bhm", "PMID:21666597" ]

An example of this is MutS in E. coli (UniProt symbol P23909) in PMID:21666597 (inferred from physical interaction).

[ "MutS mismatch repair complex" ]

[ "EXACT" ]

[]

[ "GO:0032300", "GO:1990391" ]

[]

[ "GO:0032300", "GO:1990391" ]

[]

bhm

2015-03-25T11:42:56Z

false

true

7

GO:1990711

1,990,711

beta-catenin-ICAT complex

cellular_component

Transcription factor complex that inhibits binding of Tcf to beta-catenin while preserving interaction of catenin with cadherin thus inhibiting transcription mediated by beta-catenin-Tcf complex.

[ "GOC:bhm", "PMID:12408824" ]

An example of this is Catenin beta-1 in human (UniProt symbol P35222) in PMID:12408824 (inferred from physical interaction).

[ "CTNNB1-CTNNBIP1 complex" ]

[ "EXACT" ]

[]

[ "GO:0090571" ]

[]

[ "GO:0090571" ]

[]

bhm

2015-03-25T21:08:11Z

false

true

9

GO:1990712

1,990,712

HFE-transferrin receptor complex

cellular_component

A protein complex containing at least HFE and a transferrin receptor (either TFR1/TFRC or TFR2), proposed to play a role in the sensing of transferrin-bound Fe (Fe2-Tf) on the plasma membrane to regulate hepcidin transcription.

[ "GOC:BHF", "GOC:kom", "PMID:25147378" ]

null

[]

[ "GO:0098802" ]

[]

[ "GO:0098802" ]

[]

pr

2015-03-26T13:03:27Z

false

true

4

GO:1990713

1,990,713

survivin complex

cellular_component

A protein complex that negatively regulates apoptotic processes. Complex contains a component which belongs to the family of baculoviral IAP (inhibitor of apoptosis) repeat-containing proteins.

[ "GOC:bhm", "PMID:10929712", "PMID:10949038", "PMID:16282325", "PMID:19153467" ]

An example of this is BIRC5 in human (UniProt symbol O15392) in PMID:10949038 (inferred from physical interaction).

[ "Baculoviral IAP repeat-containing protein 5 complex", "survivin homodimer complex" ]

[ "EXACT", "NARROW" ]

[]

[ "GO:0140513" ]

[]

[ "GO:0140513" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30914\" xsd:anyURI" ]

bhm

2015-03-26T14:21:46Z

false

true

4

GO:1990714

1,990,714

hydroxyproline O-galactosyltransferase activity

molecular_function

Catalysis of the transfer of galactose from UDP-galactose to hydroxyproline residues present in the peptide backbone.

[ "PMID:25600942" ]

null

[ "HPGT" ]

[ "EXACT" ]

[]

[ "GO:0008378" ]

[]

[ "GO:0008378" ]

[]

tb

2015-03-26T23:22:09Z

false

true

3

GO:1990715

1,990,715

mRNA CDS binding

molecular_function

Binding to an mRNA molecule coding sequence (CDS).

[ "GOC:kmv", "PMID:25805859", "SO:0000316" ]

null

[ "mRNA coding region binding", "mRNA coding sequence binding" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0003729" ]

[]

[ "GO:0003729" ]

[]

kmv

2015-03-27T20:59:49Z

false

true

1

GO:1990716

1,990,716

axonemal central apparatus

cellular_component

Part of the 9+2 axoneme, that occurs in most motile cilia, consisting of the pair of two single central microtubules and their associated structures which include the central pair projections, the central pair bridges linking the two tubules, and the central pair caps which are attached to the distal or plus ends of th...

[ "GOC:cilia", "PMID:21586547", "PMID:9295136" ]

null

[]

[ "GO:0110165" ]

[ "part_of GO:0005930" ]

[ "part_of" ]

[ "GO:0005930" ]

[ "GO:0005930", "GO:0110165" ]

[]

krc

2015-03-27T22:33:23Z

false

true

4

GO:1990717

1,990,717

axonemal central bridge

cellular_component

Part of the 9+2 axoneme, that occurs in most motile cilia, consisting of the two bridges which connect the central pair of single microtubules.

[ "GOC:cilia", "PMID:21586547", "PMID:9295136" ]

null

[]

[ "GO:0110165" ]

[ "part_of GO:1990716" ]

[ "part_of" ]

[ "GO:1990716" ]

[ "GO:0110165", "GO:1990716" ]

[]

krc

2015-03-27T22:38:31Z

false

true

4

GO:1990718

1,990,718

axonemal central pair projection

cellular_component

Part of the 9+2 axoneme, that occurs in most motile cilia, consisting of the projections off of the central pair of single microtubules.

[ "GOC:cilia", "PMID:21586547", "PMID:9295136" ]

null

[]

[ "GO:0110165" ]

[ "part_of GO:1990716" ]

[ "part_of" ]

[ "GO:1990716" ]

[ "GO:0110165", "GO:1990716" ]

[]

krc

2015-03-27T22:43:01Z

false

true

9

GO:1990719

1,990,719

C1 axonemal microtubule

cellular_component

One of two microtubules present in the axonemal central pair. It is distinguishable from the C2 axonemal microtubule (also called C2 tubule) by the presence of differing protein components of the projections.

[ "GOC:cilia", "PMID:21586547", "PMID:9295136" ]

null

[ "C1 tubule" ]

[ "BROAD" ]

[]

[ "GO:0005879" ]

[ "part_of GO:0097540" ]

[ "part_of" ]

[ "GO:0097540" ]

[ "GO:0005879", "GO:0097540" ]

[]

krc

2015-03-27T22:55:12Z

false

true

8

GO:1990720

1,990,720

C2 axonemal microtubule

cellular_component

One of two microtubules present in the axonemal central pair. It is distinguishable from the C1 axonemal microtubule (also called C1 tubule) by the presence of differing protein components of the projections.

[ "GOC:cilia", "PMID:21586547", "PMID:9295136" ]

null

[ "C2 tubule" ]

[ "BROAD" ]

[]

[ "GO:0005879" ]

[ "part_of GO:0097540" ]

[ "part_of" ]

[ "GO:0097540" ]

[ "GO:0005879", "GO:0097540" ]

[]

krc

2015-03-27T22:58:40Z

false

true

8

GO:1990722

1,990,722

DAPK1-calmodulin complex

cellular_component

A serine/threonine protein kinase complex involved in cell survival, apoptosis and autophagic cell death pathways. DAPK1 is activated by the dephosphorylation of a n-terminal serine and calcium-calmodulin binding.

[ "GOC:bhm", "PMID:20103772" ]

null

[ "death-associated protein kinase 1 - calmodulin complex" ]

[ "EXACT" ]

[]

[ "GO:1902554" ]

[]

[ "GO:1902554" ]

[]

bhm

2015-04-01T13:05:17Z

false

true

9

GO:1990723

1,990,723

cytoplasmic periphery of the nuclear pore complex

cellular_component

Cytoplasm situated in close proximity to a nuclear pore complex.

[ "PMID:9398662" ]

null

[ "associated with the nuclear pore" ]

[ "RELATED" ]

[]

[ "GO:0048471" ]

[]

[ "GO:0048471" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21774\" xsd:anyURI" ]

sl

2015-04-06T19:26:54Z

false

true

4

GO:1990724

1,990,724

galectin complex

cellular_component

A homodimeric protein complex that is capable of binding a range of carbohydrates and is involved in anti-inflammatory and pro-apoptotic processes.

[ "GOC:bhm", "PMID:15476813", "PMID:18777589", "PMID:8262940" ]

An example of this is Galectin-1 in human (P09382) in PMID:15476813 (inferred from physical interaction).

[ "galectin-1 complex", "galectin-2 complex" ]

[ "NARROW", "NARROW" ]

[]

[ "GO:0098635" ]

[]

[ "GO:0098635" ]

[]

bhm

2015-04-07T15:03:15Z

false

true

9

GO:1990725

1,990,725

cord factor receptor activity

molecular_function

Combining with a cord factor, an M. tuberculosis cell wall glycolipid, and transmitting a signal from one side of the membrane to the other to initiate a change in cell activity.

[ "GOC:hjd", "PMID:23602766" ]

null

[ "TMD receptor activity", "trehalose 6,6'-dimycolate receptor activity" ]

[ "EXACT", "EXACT" ]

[]

[ "Wikipedia:Cord_factor" ]

[ "GO:0038023" ]

[]

[ "GO:0038023" ]

[]

hjd

2015-04-07T20:53:31Z

false

true

9

GO:1990726

1,990,726

Lsm1-7-Pat1 complex

cellular_component

A conserved, heteroheptameric, cytoplasmic protein complex composed of Lsm1, Lsm2, Lsm3, Lsm4, Lsm5, Lsm6, Lsm7, and Pat1, or orthologs thereof, that shows a strong binding preference for oligoadenylated RNAs over polyadenylated RNAs. May bind further associated proteins. Facilitates the deadenylation-dependent decappi...

[ "GOC:bhm", "GOC:krc", "PMID:19121818", "PMID:23620288", "PMID:24139796", "PMID:27627834", "PMID:28768202" ]

null

[]

[ "GO:0120114" ]

[]

[ "GO:0120114" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/14411\" xsd:anyURI" ]

pr

2015-04-08T09:22:36Z

false

true

1

GO:1990727

1,990,727

tubulin folding cofactor complex

cellular_component

A multimeric protein complex involved in tubulin alpha-beta-subunit folding assembly consisting of beta-tubulin-TFC-D, alpha-tubulin-TFC-E and TFC-C, through which tubulin subunit association and dimer release occur.

[ "GOC:vw", "PMID:12445400" ]

null

[]

[ "GO:0032991" ]

[]

[ "GO:0032991" ]

[]

pr

2015-04-08T10:29:43Z

false

true

1