ensembl_id string | gene string | gene_description string | uniprot list | chromosome string | position string | evidence string | hpa_evidence string | uniprot_evidence string | nextprot_evidence string | antibodies list | gene_synonyms list | protein_classes list | biological_processes list | molecular_functions list | disease_involvement list | subcellular_main_locations list | subcellular_additional_locations list | secretome_locations list | secretome_functions list | reliability_if string | reliability_ih string | reliability_mouse_brain string | interactions float64 | ccd_protein string | ccd_transcript string | blood_expression_cluster string | brain_expression_cluster string | cell_line_expression_cluster string | single_cell_expression_cluster string | tissue_expression_cluster string | rna_tissue_specificity string | rna_tissue_distribution string | rna_tissue_specificity_score float64 | rna_cell_line_specificity string | rna_cell_line_distribution string | rna_cell_line_specificity_score float64 | rna_cancer_specificity string | rna_cancer_distribution string | rna_cancer_specificity_score float64 | rna_single_cell_type_specificity string | rna_single_cell_type_distribution string | rna_single_cell_type_specificity_score float64 | rna_blood_cell_specificity string | rna_blood_cell_distribution string | rna_blood_cell_specificity_score float64 | prognostic_cancer_count int64 | validated_prognostic_cancer_count int64 | potential_prognostic_cancer_count int64 | favorable_prognostic_cancers list | unfavorable_prognostic_cancers list | prognostic_cancers list | source_row_index int64 | split_bucket int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ENSG00000099953 | MMP11 | Matrix metallopeptidase 11 | [
"P24347"
] | 22 | 23768226-23784316 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB002593",
"HPA055204",
"HPA068864"
] | [
"STMY3"
] | [
"Cancer-related genes",
"Enzymes",
"Predicted secreted proteins"
] | [
"Collagen degradation"
] | [
"Hydrolase",
"Metalloprotease",
"Protease"
] | [
"Cancer-related genes"
] | [
"Golgi apparatus"
] | [
"Cytosol"
] | [
"Secreted to extracellular matrix"
] | [
"Enzyme"
] | Approved | Approved | null | null | null | null | Cluster 8: Plasmacytoid DCs - Unknown function | null | Cluster 38: Non-specific - Transcription | Cluster 105: Non-specific - Mixed function | Cluster 75: Ovary - Mixed function | Group enriched | Detected in many | 6 | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in some | null | Immune cell enriched | Detected in single | 5 | 3 | 0 | 3 | [] | [
"Glioblastoma Multiforme",
"Lung Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Lung Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 2,121 | 5 |
ENSG00000099954 | CECR2 | CECR2 histone acetyl-lysine reader | [
"Q9BXF3"
] | 22 | 17359949-17558151 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA002943"
] | [
"KIAA1740"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [] | [
"Chromatin regulator"
] | [] | [
"Nucleoplasm"
] | [
"Vesicles"
] | [] | [] | Approved | Approved | null | 9 | No | No | null | Cluster 25: Non-specific - Transcription | Cluster 33: Sarcoma - Muscle contraction | Cluster 46: Skeletal myocytes - Muscle structure & formation | Cluster 25: Non-specific - Basic cellular processes | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enriched | Detected in many | 6 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 2,122 | 1 |
ENSG00000099956 | SMARCB1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 | [
"Q12824"
] | 22 | 23786931-23838009 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB009196",
"HPA018248",
"HPA019127"
] | [
"BAF47",
"hSNFS",
"INI-1",
"Ini1",
"PPP1R144",
"RDT",
"Sfh1p",
"SNF5",
"SNF5L1",
"Snr1"
] | [
"Cancer-related genes",
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Host-virus interaction",
"Neurogenesis",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"Chromatin regulator",
"DNA-binding"
] | [
"Cancer-related genes",
"Disease variant",
"Hypotrichosis",
"Intellectual disability",
"Tumor suppressor"
] | [
"Nucleoplasm"
] | [
"Nucleoli fibrillar center"
] | [] | [] | Supported | Supported | null | 165 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 25: Non-specific - Transcription | Cluster 51: Myeloma - Immunoglobulins | Cluster 67: Plasma cells - Plasma cell differentiation | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Bladder Urothelial Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 2,123 | 3 |
ENSG00000099957 | P2RX6 | Purinergic receptor P2X 6 | [
"O15547"
] | 22 | 21009808-21028013 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA028776",
"HPA028777"
] | [
"MGC129625",
"P2RXL1",
"P2X6",
"P2XM"
] | [
"Predicted membrane proteins"
] | [
"Ion transport",
"Transport"
] | [
"Ion channel",
"Ligand-gated ion channel",
"Receptor"
] | [] | [
"Nucleoli",
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 40 | null | null | null | Cluster 24: Neurons - Mixed function | Cluster 69: Skin cancer - ECM organization | Cluster 36: Skeletal myocytes - Muscle excitation & contraction | Cluster 19: Skeletal muscle - Striated muscle contraction | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in single | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 2,124 | 8 |
ENSG00000099958 | DERL3 | Derlin 3 | [
"Q96Q80"
] | 22 | 23834503-23839128 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB037234",
"HPA049306"
] | [
"C22orf14",
"derlin-3",
"FLJ43842",
"IZP6",
"MGC71803"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [] | [] | [] | [
"Vesicles"
] | [] | [] | [] | Uncertain | Approved | null | 14 | null | null | Cluster 44: Plasmacytoid DCs - Plasma membrane proteins | Cluster 46: Brainstem - Mixed function | Cluster 51: Myeloma - Immunoglobulins | Cluster 67: Plasma cells - Plasma cell differentiation | Cluster 60: Stomach - Digestion | Tissue enhanced | Detected in many | null | Cancer enriched | Detected in many | 7 | Low cancer specificity | Detected in many | null | Cell type enriched | Detected in some | 4 | Immune cell enriched | Detected in some | 14 | 3 | 0 | 3 | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 2,125 | 4 |
ENSG00000099960 | SLC7A4 | Solute carrier family 7 member 4 | [
"O43246"
] | 22 | 21028718-21032840 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA031023"
] | [
"CAT-4",
"HCAT3",
"VH"
] | [
"Predicted membrane proteins",
"Transporters"
] | [
"Amino-acid transport",
"Transport"
] | [] | [] | [
"Vesicles",
"Plasma membrane"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Enhanced | null | null | null | null | Cluster 1: T-cells - Unknown function | Cluster 1: Neurons - Mixed function | Cluster 34: Testis cancer - Unknown function | Cluster 98: Neurons - Neurotransmission & signaling | Cluster 56: Ciliated tissues - Cilium organization | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in some | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Breast Invasive Carcinoma"
] | [] | [
"Breast Invasive Carcinoma"
] | 2,126 | 1 |
ENSG00000099968 | BCL2L13 | BCL2 like 13 | [
"Q9BXK5"
] | 22 | 17628855-17730855 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB002052",
"HPA030994",
"HPA050377"
] | [
"BCL-RAMBO",
"MIL1"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Apoptosis"
] | [] | [] | [
"Mitochondria"
] | [] | [] | [] | Enhanced | Uncertain | null | 51 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 66: Non-specific - Mitochondria | Cluster 100: Stratified epithelial cells - Barrier functions | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 2,127 | 5 |
ENSG00000099974 | DDTL | D-dopachrome tautomerase like | [
"A6NHG4"
] | 22 | 23966888-23972556 | Evidence at transcript level | Evidence at transcript level | Evidence at transcript level | Evidence at transcript level | [
"HPA074115"
] | [] | [
"Predicted intracellular proteins"
] | [] | [
"Lyase"
] | [] | [] | [] | [] | [] | null | Approved | null | null | null | null | null | null | Cluster 30: Non-specific - Gene expression regulation | Cluster 74: Microglia - Neuroimmunity & neuroinflammation | Cluster 70: Non-specific - Protein processing | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in some | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in some | null | Immune cell enriched | Detected in single | 10 | 1 | 0 | 1 | [
"Liver Hepatocellular Carcinoma"
] | [] | [
"Liver Hepatocellular Carcinoma"
] | 2,128 | 2 |
ENSG00000099977 | DDT | D-dopachrome tautomerase | [
"P30046"
] | 22 | 23970542-23980525 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA049871",
"HPA074115"
] | [
"D-DT",
"DDCT",
"MIF-2",
"MIF2"
] | [
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Melanin biosynthesis"
] | [
"Lyase"
] | [] | [
"Mitochondria"
] | [] | [] | [] | Approved | Enhanced | null | null | null | null | Cluster 29: Non-specific - Unknown function | Cluster 27: Non-specific - Mixed function | Cluster 66: Non-specific - Mitochondria | Cluster 93: Hepatocytes - Bile production & excretion | Cluster 31: Liver - Metabolism & Coagulation | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Breast Invasive Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Breast Invasive Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 2,129 | 7 |
ENSG00000099984 | GSTT2 | Glutathione S-transferase theta 2 (gene/pseudogene) | [] | 22 | 23980058-23983915 | Evidence at protein level | Evidence at protein level | null | null | [
"HPA000750"
] | [] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Cytosol"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Uncertain | null | null | No | null | null | Cluster 53: Neurons - Mixed function | Cluster 11: Neuronal - Sensory perception | Cluster 61: Schwann cells & Melanocytes - Mixed function | Cluster 37: Skin - Keratinization | Tissue enhanced | Detected in some | null | Low cancer specificity | Detected in many | null | null | null | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 2,130 | 8 |
ENSG00000099985 | OSM | Oncostatin M | [
"P13725"
] | 22 | 30262829-30266851 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"MGC20461"
] | [
"Cancer-related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [
"Growth regulation"
] | [
"Cytokine",
"Mitogen"
] | [
"Cancer-related genes"
] | [] | [] | [
"Secreted to blood"
] | [
"Cytokine"
] | null | null | null | 5 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 12: Non-specific - Vasculature | Cluster 71: Lymphoma - Inflammatory response | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 15: Bone marrow - Innate immune response | Tissue enriched | Detected in many | 8 | Cancer enhanced | Detected in some | null | Low cancer specificity | Detected in many | null | Cell type enriched | Detected in some | 6 | Group enriched | Detected in many | 8 | 1 | 0 | 1 | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | 2,131 | 3 |
ENSG00000099991 | CABIN1 | Calcineurin binding protein 1 | [
"Q9Y6J0"
] | 22 | 24011192-24178628 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA043296"
] | [
"KIAA0330",
"PPP3IN"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Chromatin regulator"
] | [] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 24 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 48: Non-specific - Mixed function | Cluster 66: Non-specific - Mitochondria | Cluster 7: Non-specific - Transcription | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Kidney Renal Papillary Cell Carcinoma",
"Pancreatic Adenocarcinoma",
"Rectum Adenocarcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | [] | [
"Kidney Renal Papillary Cell Carcinoma",
"Pancreatic Adenocarcinoma",
"Rectum Adenocarcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | 2,132 | 7 |
ENSG00000099992 | TBC1D10A | TBC1 domain family member 10A | [
"Q9BXI6"
] | 22 | 30291990-30326947 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA007725",
"HPA008142",
"HPA076041"
] | [
"AC004997.C22.2",
"EPI64",
"TBC1D10"
] | [
"Predicted intracellular proteins"
] | [] | [
"GTPase activation",
"Guanine-nucleotide releasing factor"
] | [] | [
"Plasma membrane"
] | [] | [] | [] | Enhanced | Approved | null | 10 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 66: Non-specific - Mitochondria | Cluster 91: Pituicytes/FSC - Homeostasis & neuron support | Cluster 81: Squamous epithelium - Keratinization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 2,133 | 7 |
ENSG00000099994 | SUSD2 | Sushi domain containing 2 | [
"Q9UGT4"
] | 22 | 24181487-24189106 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA004117"
] | [
"BK65A6.2",
"FLJ22778",
"W5C5"
] | [
"Predicted membrane proteins"
] | [] | [
"Receptor"
] | [
"Tumor suppressor"
] | [
"Plasma membrane"
] | [] | [] | [] | Approved | Enhanced | null | 14 | null | null | null | Cluster 19: Astrocytes - Mixed function | Cluster 27: Breast cancer - Unknown function | Cluster 81: Alveolar cells - Lung function | Cluster 14: Adipose tissue - Angiogenesis | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Lung Squamous Cell Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 2,134 | 6 |
ENSG00000099995 | SF3A1 | Splicing factor 3a subunit 1 | [
"Q15459"
] | 22 | 30331988-30356919 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000690",
"HPA030083"
] | [
"Prp21",
"PRPF21",
"SAP114",
"SF3a120"
] | [
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"mRNA processing",
"mRNA splicing"
] | [] | [] | [
"Nucleoplasm",
"Nuclear speckles"
] | [] | [] | [] | Enhanced | Enhanced | null | 299 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 16: Non-specific - Transcription | Cluster 66: Non-specific - Mitochondria | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 39: Testis - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 2,135 | 6 |
ENSG00000099998 | GGT5 | Gamma-glutamyltransferase 5 | [
"P36269"
] | 22 | 24219654-24245108 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA008121",
"CAB032489"
] | [
"GGT-REL",
"GGTLA1"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Glutathione biosynthesis",
"Leukotriene biosynthesis"
] | [
"Acyltransferase",
"Hydrolase",
"Protease",
"Transferase"
] | [] | [
"Nucleoli fibrillar center"
] | [] | [] | [] | Approved | Uncertain | null | null | null | null | Cluster 36: Eosinophils - Protein ubiquitination | Cluster 47: Endothelial cells - Vasculature | Cluster 44: Connective tissue cells - ECM organization | Cluster 110: Mural cells - ECM organization | Cluster 14: Adipose tissue - Angiogenesis | Low tissue specificity | Detected in all | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 2 | 0 | 2 | [
"Liver Hepatocellular Carcinoma"
] | [
"Stomach Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Stomach Adenocarcinoma"
] | 2,136 | 4 |
ENSG00000099999 | RNF215 | Ring finger protein 215 | [
"Q9Y6U7"
] | 22 | 30368811-30421771 | Evidence at transcript level | Evidence at transcript level | No human protein/transcript evidence | Evidence at transcript level | [
"HPA029427",
"HPA056498"
] | [] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Microtubules"
] | [
"Nucleoli"
] | [] | [] | Approved | Approved | null | 1 | null | null | Cluster 24: Non-specific - Transcription | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 15: Kidney cancer - Membrane components | Cluster 11: Muller glia cells - Retinal homeostasis | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | 2,137 | 5 |
ENSG00000100003 | SEC14L2 | SEC14 like lipid binding 2 | [
"O76054"
] | 22 | 30396941-30425303 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA064466"
] | [
"C22orf6",
"KIAA1186",
"KIAA1658",
"SPF",
"TAP",
"TAP1"
] | [
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation",
"Transport"
] | [
"Activator"
] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | Approved | null | null | null | null | Cluster 24: Non-specific - Transcription | Cluster 19: Astrocytes - Mixed function | Cluster 69: Skin cancer - ECM organization | Cluster 11: Muller glia cells - Retinal homeostasis | Cluster 45: Liver - Metabolism & Coagulation | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 3 | 2 | 2 | [
"Liver Hepatocellular Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 2,138 | 1 |
ENSG00000100012 | SEC14L3 | SEC14 like lipid binding 3 | [
"Q9UDX4"
] | 22 | 30447959-30472017 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA059450"
] | [
"TAP2"
] | [
"Predicted intracellular proteins"
] | [
"Transport"
] | [] | [] | [] | [] | [] | [] | null | Uncertain | null | null | null | null | null | Cluster 48: Non-specific - Mixed function | Cluster 7: Liver cancer - Metabolism | Cluster 11: Muller glia cells - Retinal homeostasis | Cluster 40: Non-specific - Mixed function | Tissue enhanced | Detected in some | null | Not detected | Not detected | null | Not detected | Not detected | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 2,139 | 3 |
ENSG00000100023 | PPIL2 | Peptidylprolyl isomerase like 2 | [
"Q13356"
] | 22 | 21666000-21700015 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA035344",
"HPA055637"
] | [
"CYC4",
"Cyp-60",
"UBOX7"
] | [
"Enzymes",
"Essential proteins",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"mRNA processing",
"mRNA splicing",
"Ubl conjugation pathway"
] | [
"Transferase"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Supported | null | 13 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 14: Neurons - Synaptic function | Cluster 66: Non-specific - Mitochondria | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 2,141 | 8 |
ENSG00000100027 | YPEL1 | Yippee like 1 | [
"O60688"
] | 22 | 21697536-21735794 | Evidence at protein level | Evidence at transcript level | No human protein/transcript evidence | Evidence at transcript level | [
"HPA030501",
"HPA045621"
] | [] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Uncertain | null | null | null | null | Cluster 8: Plasmacytoid DCs - Unknown function | Cluster 33: Neurons - Mixed function | Cluster 6: Leukemia - Signal transduction | Cluster 53: Late primary spermatocytes - Meiotic division & transition | Cluster 67: Testis - Mixed function | Tissue enriched | Detected in all | 5 | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in many | 9 | Low immune cell specificity | Detected in some | null | 2 | 0 | 2 | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 2,143 | 7 |
ENSG00000100028 | SNRPD3 | Small nuclear ribonucleoprotein D3 polypeptide | [
"P62318"
] | 22 | 24555958-24582052 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001170"
] | [
"Sm-D3",
"SMD3"
] | [
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"mRNA processing",
"mRNA splicing"
] | [
"Ribonucleoprotein",
"RNA-binding"
] | [] | [
"Nucleoplasm"
] | [
"Nuclear bodies",
"Cytosol"
] | [] | [] | Supported | Supported | null | 101 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 31: Non-specific - Transcription | Cluster 66: Non-specific - Mitochondria | Cluster 15: Non-specific - Protein processing | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 2,144 | 3 |
ENSG00000100029 | PES1 | Pescadillo ribosomal biogenesis factor 1 | [
"O00541"
] | 22 | 30576625-30607083 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA040210",
"HPA062439",
"HPA066670"
] | [
"NOP7",
"PES"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Ribosome biogenesis",
"rRNA processing"
] | [] | [] | [
"Nucleoli",
"Nucleoli rim",
"Mitotic chromosome"
] | [
"Nucleoplasm"
] | [] | [] | Enhanced | Supported | null | 58 | Yes | Yes | Cluster 13: Non-specific - Mitochondria | Cluster 27: Non-specific - Mixed function | Cluster 66: Non-specific - Mitochondria | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 2 | 1 | [] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 2,145 | 2 |
ENSG00000100030 | MAPK1 | Mitogen-activated protein kinase 1 | [
"P28482"
] | 22 | 21759657-21867680 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003995",
"CAB004229",
"HPA005700",
"HPA030069",
"CAB079932",
"CAB079933"
] | [
"ERK",
"ERK2",
"MAPK2",
"p41mapk",
"PRKM1",
"PRKM2"
] | [
"Cancer-related genes",
"Disease related genes",
"Enzymes",
"FDA approved drug targets",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"RAS pathway related proteins"
] | [
"Apoptosis",
"Cell cycle",
"Host-virus interaction",
"Transcription",
"Transcription regulation"
] | [
"DNA-binding",
"Kinase",
"Repressor",
"Serine/threonine-protein kinase",
"Transferase"
] | [
"Cancer-related genes",
"Disease variant",
"FDA approved drug targets"
] | [
"Nucleoplasm"
] | [
"Microtubules",
"Primary cilium",
"Primary cilium tip",
"Basal body",
"Cytosol"
] | [] | [] | Supported | Enhanced | null | 193 | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 33: Neurons - Mixed function | Cluster 66: Non-specific - Mitochondria | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 73: Brain - Neuronal signaling | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 2,146 | 7 |
ENSG00000100031 | GGT1 | Gamma-glutamyltransferase 1 | [
"P19440"
] | 22 | 24594811-24629005 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA045635",
"HPA047534",
"HPA065444"
] | [
"CD224",
"D22S672",
"D22S732",
"GGT"
] | [
"Candidate cardiovascular disease genes",
"CD markers",
"Disease related genes",
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Glutathione biosynthesis",
"Lipid metabolism"
] | [
"Acyltransferase",
"Hydrolase",
"Protease",
"Transferase"
] | [
"Disease variant",
"Intellectual disability"
] | [
"Vesicles"
] | [] | [
"Intracellular and membrane"
] | [
"Enzyme"
] | Uncertain | Supported | null | 4 | null | null | Cluster 28: Neutrophils - Unknown function | Cluster 30: White matter - Myelination | Cluster 15: Kidney cancer - Membrane components | Cluster 88: Proximal tubular cells - Transmembrane transport | Cluster 26: Kidney & Intestine - Metabolism | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in some | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Bladder Urothelial Carcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 2,147 | 7 |
ENSG00000100033 | PRODH | Proline dehydrogenase 1 | [
"O43272"
] | 22 | 18912777-18936553 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA020361"
] | [
"HSPOX2",
"PIG6",
"PRODH1",
"PRODH2",
"TP53I6"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Proline metabolism"
] | [
"Oxidoreductase"
] | [
"Disease variant",
"Schizophrenia"
] | [
"Mitochondria"
] | [
"Nucleoplasm",
"Vesicles"
] | [] | [] | Approved | Approved | null | null | null | null | null | Cluster 42: Choroid plexus - Mitochondria | Cluster 27: Breast cancer - Unknown function | Cluster 28: Astrocytes - Homeostasis & neuron support | Cluster 1: Choroid plexus - Transmembrane transport | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enriched | Detected in many | 4 | Group enriched | Detected in some | 4 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 2,148 | 1 |
ENSG00000100036 | SLC35E4 | Solute carrier family 35 member E4 | [
"Q6ICL7"
] | 22 | 30635781-30669016 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA049558"
] | [] | [
"Predicted membrane proteins",
"Transporters"
] | [] | [] | [] | [
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 12 | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 48: Non-specific - Mixed function | Cluster 72: Neuronal - Signal transduction | Cluster 36: Skeletal myocytes - Muscle excitation & contraction | Cluster 67: Testis - Mixed function | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in single | null | 2 | 0 | 2 | [] | [
"Bladder Urothelial Carcinoma",
"Kidney Chromophobe"
] | [
"Bladder Urothelial Carcinoma",
"Kidney Chromophobe"
] | 2,150 | 4 |
ENSG00000100038 | TOP3B | DNA topoisomerase III beta | [
"O95985"
] | 22 | 21957025-21982813 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA072114"
] | [] | [
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"DNA-binding",
"Isomerase",
"Topoisomerase"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | null | null | 113 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 48: Non-specific - Mixed function | Cluster 66: Non-specific - Mitochondria | Cluster 7: Non-specific - Transcription | Cluster 49: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 2,151 | 7 |
ENSG00000100053 | CRYBB3 | Crystallin beta B3 | [
"P26998"
] | 22 | 25199858-25207359 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA055840"
] | [
"CRYB3"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [
"Eye lens protein"
] | [
"Cataract",
"Disease variant"
] | [
"Microtubules"
] | [
"Cytokinetic bridge",
"Mitotic spindle"
] | [] | [] | Approved | Supported | null | 37 | Yes | null | null | Cluster 38: Sub-cortical - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 46: Skeletal myocytes - Muscle structure & formation | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in some | null | Low cancer specificity | Detected in some | null | Low cancer specificity | Detected in some | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 2,152 | 1 |
ENSG00000100055 | CYTH4 | Cytohesin 4 | [
"Q9UIA0"
] | 22 | 37282027-37315341 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA004065",
"HPA071573"
] | [
"CYT4",
"cytohesin-4",
"PSCD4"
] | [
"Predicted intracellular proteins"
] | [] | [
"Guanine-nucleotide releasing factor"
] | [] | [
"Plasma membrane"
] | [
"Cytokinetic bridge",
"Centriolar satellite",
"Cytosol"
] | [] | [] | Supported | Approved | null | 21 | Yes | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 20: Macrophages & Microglia - Immune response | Cluster 71: Lymphoma - Inflammatory response | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 66: Lymphoid tissue - Immune response | Tissue enhanced | Detected in many | null | Group enriched | Detected in some | 13 | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in some | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Pancreatic Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | 2,153 | 7 |
ENSG00000100060 | MFNG | MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | [
"O00587"
] | 22 | 37469063-37486393 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA048936",
"HPA056479"
] | [] | [
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Developmental protein",
"Glycosyltransferase",
"Transferase"
] | [] | [
"Vesicles"
] | [] | [
"Intracellular and membrane"
] | [
"Developmental protein"
] | Approved | Approved | null | null | null | null | Cluster 36: Eosinophils - Protein ubiquitination | Cluster 49: Hindbrain - Mixed function | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 47: Platelets - Hemostasis | Cluster 66: Lymphoid tissue - Immune response | Tissue enhanced | Detected in many | null | Group enriched | Detected in many | 6 | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Lung Adenocarcinoma"
] | [] | [
"Lung Adenocarcinoma"
] | 2,155 | 7 |
ENSG00000100065 | CARD10 | Caspase recruitment domain family member 10 | [
"Q9BWT7"
] | 22 | 37490362-37519542 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA029359",
"HPA074912"
] | [
"BIMP1",
"CARMA3"
] | [
"Disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 94 | null | No | null | Cluster 49: Hindbrain - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 77: Intestine - Digestion | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 2,156 | 4 |
ENSG00000100075 | SLC25A1 | Solute carrier family 25 member 1 | [
"P53007"
] | 22 | 19175581-19178739 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"CTP",
"SLC20A3"
] | [
"Disease related genes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Transporters"
] | [
"Antiport",
"Transport"
] | [] | [
"Congenital myasthenic syndrome",
"Disease variant"
] | [] | [] | [] | [] | null | null | null | 15 | null | null | Cluster 45: Eosinophils - Unknown function | Cluster 41: Monoamines - Neurotransmitter signalling | Cluster 66: Non-specific - Mitochondria | Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion | Cluster 70: Non-specific - Protein processing | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 2,157 | 5 |
ENSG00000100077 | GRK3 | G protein-coupled receptor kinase 3 | [
"P35626"
] | 22 | 25564675-25729294 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000804"
] | [
"ADRBK2",
"BARK2"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [] | [
"Nucleoplasm"
] | [
"Plasma membrane"
] | [] | [] | Approved | Uncertain | null | 4 | null | null | Cluster 23: B-cells - Immunoglobulins | Cluster 51: Neurons - Mixed function | Cluster 59: Leukemia - T-cell receptor | Cluster 89: Adipocytes - Lipid metabolism | Cluster 18: Lymphoid tissue - Immune response | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 9 | 0 | 0 | 0 | [] | [] | [] | 2,158 | 5 |
ENSG00000100078 | PLA2G3 | Phospholipase A2 group III | [
"Q9NZ20"
] | 22 | 31134807-31140508 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA021016"
] | [
"GIII-SPLA2"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted secreted proteins",
"RAS pathway related proteins"
] | [
"Cilium biogenesis/degradation",
"Lipid metabolism",
"Mast cell degranulation",
"Phospholipid metabolism"
] | [
"Hydrolase"
] | [] | [
"Endoplasmic reticulum",
"Golgi apparatus"
] | [] | [
"Secreted to blood"
] | [
"Enzyme"
] | Approved | Uncertain | null | null | null | null | null | Cluster 49: Hindbrain - Mixed function | Cluster 12: Bone cancer - Neuronal signaling | Cluster 4: Breast lactating luminal cells - Lactation | Cluster 81: Squamous epithelium - Keratinization | Group enriched | Detected in some | 4 | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Head and Neck Squamous Cell Carcinoma"
] | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Head and Neck Squamous Cell Carcinoma"
] | 2,159 | 9 |
ENSG00000100079 | LGALS2 | Galectin 2 | [
"P05162"
] | 22 | 37570248-37582616 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003536",
"CAB025198"
] | [
"HL14"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Mitochondria"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Enhanced | null | 7 | null | null | Cluster 26: Monocytes - Plasma membrane proteins | Cluster 11: White matter - Signal transduction | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 1: Enterocytes - Absorption and Digestion | Cluster 60: Stomach - Digestion | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Group enriched | Detected in all | 4 | Cell type enhanced | Detected in many | null | Group enriched | Detected in all | 27 | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | 2,160 | 9 |
ENSG00000100083 | GGA1 | Golgi associated, gamma adaptin ear containing, ARF binding protein 1 | [
"Q9UJY5"
] | 22 | 37608725-37633564 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA048280",
"HPA051016"
] | [] | [
"Predicted intracellular proteins",
"Transporters"
] | [
"Protein transport",
"Transport"
] | [] | [] | [
"Golgi apparatus",
"Vesicles"
] | [
"Nucleoplasm"
] | [] | [] | Supported | Supported | null | 53 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 6: Non-specific - Immune response | Cluster 66: Non-specific - Mitochondria | Cluster 53: Late primary spermatocytes - Meiotic division & transition | Cluster 67: Testis - Mixed function | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 2,161 | 1 |
ENSG00000100084 | HIRA | Histone cell cycle regulator | [
"P54198"
] | 22 | 19330698-19447450 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB039243",
"CAB039244",
"HPA050714",
"HPA052902"
] | [
"DGCR1",
"TUP1",
"TUPLE1"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"Chromatin regulator",
"Repressor"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Enhanced | null | 40 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 38: Sub-cortical - Mixed function | Cluster 66: Non-specific - Mitochondria | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 33: Thyroid gland - Tissue development | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 2,162 | 5 |
ENSG00000100095 | SEZ6L | Seizure related 6 homolog like | [
"Q9BYH1"
] | 22 | 26169462-26383597 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA045135"
] | [] | [
"Predicted membrane proteins"
] | [] | [] | [] | [
"Vesicles"
] | [] | [] | [] | Approved | null | null | null | null | null | Cluster 40: Monocytes - Innate immune response | Cluster 1: Neurons - Mixed function | Cluster 12: Bone cancer - Neuronal signaling | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 10: Brain - Synaptic signal transduction | Tissue enriched | Detected in some | 5 | Group enriched | Detected in some | 5 | Cancer enriched | Detected in some | 4 | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 6 | 1 | 0 | 1 | [
"Pancreatic Adenocarcinoma"
] | [] | [
"Pancreatic Adenocarcinoma"
] | 2,164 | 9 |
ENSG00000100097 | LGALS1 | Galectin 1 | [
"P09382"
] | 22 | 37675636-37679802 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000646",
"HPA001130",
"CAB002157"
] | [
"GBP"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [
"Apoptosis"
] | [] | [] | [
"Cytosol"
] | [] | [
"Secreted to blood"
] | [
"Other"
] | Supported | Enhanced | null | 89 | No | Yes | Cluster 26: Monocytes - Plasma membrane proteins | Cluster 45: Non-specific - Mixed function | Cluster 66: Non-specific - Mitochondria | Cluster 108: Fibroblasts - ECM organization | Cluster 74: Non-specific - Signal transduction | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 5 | 2 | 4 | [
"Skin Cutaneous Melanoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Skin Cutaneous Melanoma"
] | 2,165 | 6 |
ENSG00000100099 | HPS4 | HPS4 biogenesis of lysosomal organelles complex 3 subunit 2 | [
"Q9NQG7"
] | 22 | 26443107-26483931 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003375",
"CAB033106",
"HPA050189"
] | [
"BLOC3S2",
"KIAA1667",
"LE"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [
"Guanine-nucleotide releasing factor"
] | [
"Albinism",
"Hermansky-Pudlak syndrome"
] | [
"Plasma membrane"
] | [] | [] | [] | Approved | Approved | null | 2 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 41: Monoamines - Neurotransmitter signalling | Cluster 6: Leukemia - Signal transduction | Cluster 66: Erythroid cells - Erythroid differentiation and maturation | Cluster 2: Non-specific - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 2,166 | 9 |
ENSG00000100100 | PIK3IP1 | Phosphoinositide-3-kinase interacting protein 1 | [
"Q96FE7"
] | 22 | 31281594-31292534 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"HGFL",
"MGC17330",
"TrIP"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | null | null | 7 | null | Yes | Cluster 39: T-cells - T-cell receptor | Cluster 30: White matter - Myelination | Cluster 64: Connective tissue cells - ECM organization | Cluster 9: T-cells - Adaptive immunity: Regulation | Cluster 66: Lymphoid tissue - Immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 2,167 | 8 |
ENSG00000100104 | SRRD | SRR1 domain containing | [
"Q9UH36"
] | 22 | 26483877-26494658 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA002945"
] | [
"HC/HCC",
"SRR1L"
] | [
"Predicted intracellular proteins"
] | [
"Biological rhythms",
"Heme biosynthesis"
] | [] | [] | [
"Cytosol"
] | [] | [] | [] | Approved | Uncertain | null | null | null | null | Cluster 24: Non-specific - Transcription | Cluster 15: Non-specific - Transcription | Cluster 6: Leukemia - Signal transduction | Cluster 17: Non-specific - RNA processing | Cluster 19: Skeletal muscle - Striated muscle contraction | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 4 | 2 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 2,168 | 7 |
ENSG00000100105 | PATZ1 | POZ/BTB and AT hook containing zinc finger 1 | [
"Q9HBE1"
] | 22 | 31325804-31346346 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA047893",
"HPA048315"
] | [
"dJ400N23",
"MAZR",
"PATZ",
"RIAZ",
"ZBTB19",
"ZNF278",
"ZSG"
] | [
"Cancer-related genes",
"Disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding",
"Repressor"
] | [
"Cancer-related genes",
"Proto-oncogene"
] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Approved | null | 7 | No | No | Cluster 30: Non-specific - DNA binding | Cluster 13: Oligodendrocytes - Mixed function | Cluster 66: Non-specific - Mitochondria | Cluster 4: Breast lactating luminal cells - Lactation | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 2,169 | 5 |
ENSG00000100106 | TRIOBP | TRIO and F-actin binding protein | [
"Q9H2D6"
] | 22 | 37697048-37776556 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003747",
"HPA019769"
] | [
"DFNB28",
"HRIHFB2122",
"KIAA1662",
"TAP68",
"Tara"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Mitosis"
] | [
"Actin-binding"
] | [
"Deafness",
"Disease variant",
"Non-syndromic deafness"
] | [] | [] | [] | [] | null | Enhanced | null | 19 | null | null | Cluster 7: Non-specific - Innate immune response | Cluster 47: Endothelial cells - Vasculature | Cluster 66: Non-specific - Mitochondria | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 35: Non-specific - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 2,170 | 5 |
ENSG00000100109 | TFIP11 | Tuftelin interacting protein 11 | [
"Q9UBB9"
] | 22 | 26491225-26512505 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA027085"
] | [
"DKFZP434B194",
"Spp382",
"TIP39"
] | [
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Biomineralization",
"mRNA processing",
"mRNA splicing"
] | [] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Approved | null | null | 262 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 66: Non-specific - Mitochondria | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 2,171 | 4 |
ENSG00000100116 | GCAT | Glycine C-acetyltransferase | [
"O75600"
] | 22 | 37807905-37817176 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA020460",
"HPA063924"
] | [
"KBL"
] | [
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Acyltransferase",
"Transferase"
] | [] | [
"Nuclear speckles"
] | [
"Nucleoplasm",
"Mitochondria"
] | [] | [] | Supported | Approved | null | 21 | Yes | No | Cluster 11: T-cells - Unknown function | Cluster 45: Non-specific - Mixed function | Cluster 66: Non-specific - Mitochondria | Cluster 84: Apical squamous epithelium - Cornification | Cluster 70: Non-specific - Protein processing | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Breast Invasive Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 2,172 | 4 |
ENSG00000100121 | GGTLC2 | Gamma-glutamyltransferase light chain 2 | [
"Q14390"
] | 22 | 22644614-22647898 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA045635",
"HPA047534"
] | [
"GGTL4"
] | [
"Essential proteins",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Uncertain | null | 1 | null | null | Cluster 20: Non-specific - DNA binding | Cluster 6: Non-specific - Immune response | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 56: Late spermatids - Spermiogenesis: Maturation | Cluster 47: Testis - Mixed function | Tissue enriched | Detected in some | 8 | Low cancer specificity | Detected in some | null | Cancer enhanced | Detected in some | null | Group enriched | Detected in some | 12 | Low immune cell specificity | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 2,173 | 6 |
ENSG00000100122 | CRYBB1 | Crystallin beta B1 | [
"P53674"
] | 22 | 26599278-26618027 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003448",
"CAB010058"
] | [] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Eye lens protein"
] | [
"Cataract",
"Disease variant"
] | [] | [] | [] | [] | null | Supported | null | 6 | null | null | Cluster 40: Monocytes - Innate immune response | Cluster 20: Macrophages & Microglia - Immune response | Cluster 51: Myeloma - Immunoglobulins | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 22: Epididymis - Mixed function | Tissue enhanced | Detected in some | null | Cancer enriched | Detected in some | 6 | Group enriched | Detected in many | 6 | Cell type enriched | Detected in some | 4 | Group enriched | Detected in some | 6 | 0 | 0 | 0 | [] | [] | [] | 2,174 | 6 |
ENSG00000100129 | EIF3L | Eukaryotic translation initiation factor 3 subunit L | [
"Q9Y262"
] | 22 | 37848868-37889407 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA003028"
] | [
"EIF3EIP",
"EIF3S11",
"EIF3S6IP",
"HSPC021",
"HSPC025"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Protein biosynthesis"
] | [
"Initiation factor"
] | [] | [
"Nucleoli"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Approved | null | 101 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 10: Cerebellum - Nucleic acid binding | Cluster 25: Non-specific - Ribosome | Cluster 17: Non-specific - RNA processing | Cluster 54: Non-specific - Ribosome | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe"
] | 2,176 | 5 |
ENSG00000100138 | SNU13 | Small nuclear ribonucleoprotein 13 | [
"P55769"
] | 22 | 41673933-41690504 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA029199"
] | [
"15.5K",
"FA-1",
"NHP2L1",
"SNRNP15-5",
"SPAG12",
"SSFA1"
] | [
"Essential proteins",
"Predicted intracellular proteins",
"Ribosomal proteins"
] | [
"mRNA processing",
"mRNA splicing"
] | [
"Ribonucleoprotein",
"RNA-binding"
] | [] | [] | [] | [] | [] | null | Uncertain | null | 59 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 1: Neurons - Mixed function | Cluster 66: Non-specific - Mitochondria | Cluster 17: Non-specific - RNA processing | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 2,177 | 4 |
ENSG00000100139 | MICALL1 | MICAL like 1 | [
"Q8N3F8"
] | 22 | 37905657-37942822 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA043480",
"HPA051956"
] | [
"KIAA1668",
"MICAL-L1",
"MIRAB13"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Endocytosis",
"Protein transport",
"Transport"
] | [] | [] | [
"Cell Junctions",
"Centriolar satellite",
"Cytosol"
] | [] | [] | [] | Supported | Approved | null | 28 | null | null | Cluster 30: Non-specific - DNA binding | Cluster 30: White matter - Myelination | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 63: Cytotrophoblasts - Basic cellular functions | Cluster 11: Esophagus - Basic cellular processes | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 2,178 | 3 |
ENSG00000100142 | POLR2F | RNA polymerase II, I and III subunit F | [
"P61218"
] | 22 | 37952607-38041915 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000827",
"CAB009882"
] | [
"HRBP14.4",
"RPB6"
] | [
"Essential proteins",
"Metabolic proteins",
"Predicted intracellular proteins",
"RNA polymerase related proteins"
] | [
"Transcription"
] | [] | [] | [
"Nucleoplasm",
"Nucleoli fibrillar center"
] | [] | [] | [] | Supported | Supported | null | 178 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 11: White matter - Signal transduction | Cluster 66: Non-specific - Mitochondria | Cluster 80: Oligodendrocytes - Myelination | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme"
] | [
"Kidney Chromophobe"
] | [
"Glioblastoma Multiforme",
"Kidney Chromophobe"
] | 2,179 | 4 |
ENSG00000100146 | SOX10 | SRY-box transcription factor 10 | [
"P56693"
] | 22 | 37970686-37987422 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB003171",
"HPA068898"
] | [
"DOM",
"SOX-10",
"WS2E",
"WS4"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding"
] | [
"Deafness",
"Disease variant",
"Hirschsprung disease",
"Kallmann syndrome",
"Waardenburg syndrome"
] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Enhanced | null | 20 | Yes | null | null | Cluster 11: White matter - Signal transduction | Cluster 69: Skin cancer - ECM organization | Cluster 61: Schwann cells & Melanocytes - Mixed function | Cluster 3: Oligodendrocytes - Myelination | Group enriched | Detected in many | 5 | Cancer enriched | Detected in some | 16 | Cancer enriched | Detected in many | 9 | Group enriched | Detected in many | 6 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 2,180 | 2 |
ENSG00000100147 | CCDC134 | Coiled-coil domain containing 134 | [
"Q9H6E4"
] | 22 | 41800679-41832164 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003936",
"HPA075348"
] | [
"FLJ22349"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted secreted proteins"
] | [] | [] | [
"Osteogenesis imperfecta"
] | [
"Cytosol"
] | [
"Vesicles"
] | [
"Secreted to blood"
] | [
"No annotated function"
] | Supported | Approved | null | 3 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 25: Non-specific - Transcription | Cluster 66: Non-specific - Mitochondria | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 40: Non-specific - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 2,181 | 2 |
ENSG00000100150 | DEPDC5 | DEP domain containing 5, GATOR1 subcomplex subunit | [
"O75140"
] | 22 | 31753867-31908033 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA054969",
"HPA055619"
] | [
"DEP.5",
"KIAA0645"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [
"GTPase activation"
] | [
"Disease variant",
"Epilepsy",
"Intellectual disability"
] | [] | [] | [] | [] | null | Uncertain | null | 15 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 53: Neurons - Mixed function | Cluster 66: Non-specific - Mitochondria | Cluster 22: Non-specific - Basic cellular functions | Cluster 66: Lymphoid tissue - Immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in some | 5 | Immune cell enhanced | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 2,182 | 1 |
ENSG00000100151 | PICK1 | Protein interacting with PRKCA 1 | [
"Q9NRD5"
] | 22 | 38056311-38075701 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000819",
"HPA072674"
] | [
"dJ1039K5",
"MGC15204",
"PRKCABP"
] | [
"Predicted intracellular proteins",
"Transporters"
] | [] | [
"Actin-binding"
] | [] | [
"Cytosol"
] | [] | [] | [] | Supported | Approved | null | 331 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 28: Oligodendrocytes - Mixed function | Cluster 66: Non-specific - Mitochondria | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 69: Parathyroid gland - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 2,183 | 1 |
ENSG00000100154 | TTC28 | Tetratricopeptide repeat domain 28 | [
"Q96AY4"
] | 22 | 27978014-28679840 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA001080"
] | [
"KIAA1043"
] | [
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Mitosis"
] | [] | [] | [
"Microtubules",
"Cytokinetic bridge",
"Mitotic spindle"
] | [
"Cytosol"
] | [] | [] | Approved | null | null | 9 | Yes | null | null | Cluster 51: Neurons - Mixed function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 75: Ovary - Mixed function | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 2 | 1 | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 2,184 | 8 |
ENSG00000100156 | SLC16A8 | Solute carrier family 16 member 8 | [
"O95907"
] | 22 | 38078134-38084184 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA075017"
] | [
"MCT3",
"REMP"
] | [
"Metabolic proteins",
"Plasma proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Symport",
"Transport"
] | [] | [] | [
"Focal adhesion sites"
] | [
"Intermediate filaments"
] | [] | [] | Approved | Approved | null | null | No | null | null | Cluster 11: White matter - Signal transduction | Cluster 16: Thyroid cancer - Neuronal signaling | Cluster 99: Retinal pigment epithelial cells - Retinol metabolism | Cluster 2: Non-specific - Mixed function | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in some | null | Not detected | Not detected | null | Cell type enriched | Detected in many | 19 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 2,185 | 5 |
ENSG00000100162 | CENPM | Centromere protein M | [
"Q9NSP4"
] | 22 | 41938737-41947152 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA042404"
] | [
"C22orf18",
"CENP-M",
"MGC861",
"Pane1"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Enhanced | null | 15 | null | null | Cluster 16: Non-specific - Cell proliferation | Cluster 15: Non-specific - Transcription | Cluster 35: RS4;11 - Unknown function | Cluster 27: Non-specific - Cell proliferation | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 7 | 4 | 5 | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Glioblastoma Multiforme"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Glioblastoma Multiforme",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 2,186 | 4 |
ENSG00000100167 | SEPTIN3 | Septin 3 | [
"Q9UH03"
] | 22 | 41969443-41998221 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003548",
"CAB017633"
] | [
"SEP3",
"SEPT3"
] | [
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division"
] | [] | [] | [
"Plasma membrane",
"Actin filaments"
] | [
"Nucleoplasm",
"Primary cilium"
] | [] | [] | Approved | Supported | Supported | 35 | null | null | null | Cluster 51: Neurons - Mixed function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 10: Brain - Synaptic signal transduction | Tissue enriched | Detected in many | 10 | Cancer enhanced | Detected in many | null | Group enriched | Detected in many | 5 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Glioblastoma Multiforme"
] | [] | [
"Glioblastoma Multiforme"
] | 2,187 | 3 |
ENSG00000100170 | SLC5A1 | Solute carrier family 5 member 1 | [
"P13866"
] | 22 | 32043261-32113029 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB015467",
"HPA051805",
"HPA055106"
] | [
"D22S675",
"NAGT",
"SGLT1"
] | [
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Ion transport",
"Sodium transport",
"Sugar transport",
"Symport",
"Transport"
] | [] | [
"Disease variant",
"FDA approved drug targets"
] | [
"Golgi apparatus",
"Plasma membrane"
] | [
"Nuclear membrane"
] | [] | [] | Approved | Enhanced | null | 1 | null | null | null | Cluster 9: Non-specific - Receptor signaling | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 1: Enterocytes - Absorption and Digestion | Cluster 7: Small intestine - Absorption and Digestion | Tissue enriched | Detected in many | 7 | Group enriched | Detected in some | 4 | Cancer enhanced | Detected in many | null | Cell type enriched | Detected in many | 8 | Not detected in immune cells | Not detected | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 2,188 | 5 |
ENSG00000100191 | SLC5A4 | Solute carrier family 5 member 4 | [
"Q9NY91"
] | 22 | 32218464-32255347 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"DJ90G24.4",
"SAAT1",
"SGLT3"
] | [
"Predicted membrane proteins",
"Transporters"
] | [
"Ion transport",
"Sodium transport",
"Transport"
] | [] | [] | [] | [] | [] | [] | null | null | null | 5 | null | null | null | Cluster 24: Neurons - Mixed function | Cluster 9: Skin cancer - Melanin biosynthesis | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 7: Small intestine - Absorption and Digestion | Tissue enriched | Detected in some | 13 | Cancer enriched | Detected in some | 21 | Cancer enriched | Detected in some | 7 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 2,189 | 2 |
ENSG00000100196 | KDELR3 | KDEL endoplasmic reticulum protein retention receptor 3 | [
"O43731"
] | 22 | 38468078-38483447 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA043477",
"HPA076405"
] | [] | [
"Predicted membrane proteins"
] | [
"ER-Golgi transport",
"Protein transport",
"Transport"
] | [
"Receptor"
] | [] | [
"Endoplasmic reticulum"
] | [] | [] | [] | Supported | Uncertain | null | 19 | No | No | Cluster 14: Non-specific - Unknown function | Cluster 16: Non-specific - Transcription | Cluster 64: Connective tissue cells - ECM organization | Cluster 108: Fibroblasts - ECM organization | Cluster 60: Stomach - Digestion | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in single | null | 3 | 2 | 2 | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 2,190 | 4 |
ENSG00000100197 | CYP2D6 | Cytochrome P450 family 2 subfamily D member 6 | [
"P10635"
] | 22 | 42126499-42130865 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA045223"
] | [
"CPD6",
"CYP2D",
"CYP2D7AP",
"CYP2D7BP",
"CYP2D7P2",
"CYP2D8P2",
"CYP2DL1",
"P450-DB1",
"P450C2D"
] | [
"Human disease related genes",
"Metabolic proteins",
"Predicted membrane proteins"
] | [
"Cholesterol metabolism",
"Fatty acid metabolism",
"Lipid metabolism",
"Steroid metabolism",
"Sterol metabolism"
] | [
"Monooxygenase",
"Oxidoreductase"
] | [] | [
"Golgi apparatus"
] | [] | [] | [] | Approved | Enhanced | null | null | No | No | null | Cluster 15: Non-specific - Transcription | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 1: Enterocytes - Absorption and Digestion | Cluster 31: Liver - Metabolism & Coagulation | Tissue enriched | Detected in some | 25 | Not detected | Not detected | null | Cancer enriched | Detected in single | 159 | Group enriched | Detected in some | 13 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 2,191 | 8 |
ENSG00000100201 | DDX17 | DEAD-box helicase 17 | [
"Q92841"
] | 22 | 38483438-38507660 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB024908",
"HPA063142"
] | [
"P72"
] | [
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Antiviral defense",
"Immunity",
"mRNA processing",
"mRNA splicing",
"RNA-mediated gene silencing",
"rRNA processing",
"Transcription",
"Transcription regulation"
] | [
"Helicase",
"Hydrolase",
"RNA-binding"
] | [] | [
"Nuclear speckles"
] | [] | [
"Intracellular and membrane"
] | [
"Transcription"
] | Supported | Supported | null | 123 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 50: Non-specific - Nucleic acid binding | Cluster 66: Non-specific - Mitochondria | Cluster 7: Non-specific - Transcription | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 2,192 | 8 |
ENSG00000100206 | DMC1 | DNA meiotic recombinase 1 | [
"Q14565"
] | 22 | 38518948-38570204 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001232",
"CAB015397"
] | [
"LIM15"
] | [
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Meiosis"
] | [
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Enhanced | null | 15 | null | null | null | Cluster 37: Neurons - Mixed function | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 3: Early primary spermatocytes - Early meiosis | Cluster 39: Testis - Nuclear processes | Tissue enhanced | Detected in some | null | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enriched | Detected in many | 10 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 2,193 | 5 |
ENSG00000100207 | TCF20 | Transcription factor 20 | [
"Q9UGU0"
] | 22 | 42160013-42343616 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB017849",
"HPA036786"
] | [
"AR1",
"SPBP"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding"
] | [
"Disease variant",
"Intellectual disability"
] | [
"Nucleoplasm"
] | [
"Nuclear bodies"
] | [] | [] | Supported | Approved | null | 18 | null | null | null | Cluster 51: Neurons - Mixed function | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 102: Non-specific - Mixed function | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | 2,194 | 8 |
ENSG00000100209 | HSCB | HscB mitochondrial iron-sulfur cluster cochaperone | [
"Q8IWL3"
] | 22 | 28742039-28757515 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA018447",
"HPA031518"
] | [
"DNAJC20",
"HSC20",
"Jac1"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [
"Chaperone"
] | [] | [
"Nucleoplasm",
"Mitochondria",
"Cytosol"
] | [] | [] | [] | Supported | Uncertain | null | 89 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 27: Non-specific - Mixed function | Cluster 66: Non-specific - Mitochondria | Cluster 15: Non-specific - Protein processing | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 2,195 | 6 |
ENSG00000100211 | CBY1 | Chibby family member 1, beta catenin antagonist | [
"Q9Y3M2"
] | 22 | 38656636-38673854 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA020360"
] | [
"C22orf2",
"Cby",
"Chibby",
"Chibby1",
"PGEA1",
"PIGEA-14",
"PIGEA14"
] | [
"Predicted intracellular proteins"
] | [
"Cilium biogenesis/degradation",
"Differentiation"
] | [] | [] | [
"Centrosome"
] | [
"Nucleoplasm",
"Nucleoli"
] | [] | [] | Supported | null | null | 42 | null | null | Cluster 24: Non-specific - Transcription | Cluster 19: Astrocytes - Mixed function | Cluster 66: Non-specific - Mitochondria | Cluster 107: Ciliated cells - Cilia assembly & function | Cluster 75: Ovary - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 2,196 | 4 |
ENSG00000100216 | TOMM22 | Translocase of outer mitochondrial membrane 22 | [
"Q9NS69"
] | 22 | 38681957-38685421 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003037",
"HPA074642"
] | [
"TOM22"
] | [
"Essential proteins",
"Predicted membrane proteins"
] | [
"Protein transport",
"Translocation",
"Transport"
] | [
"Receptor"
] | [] | [
"Mitochondria"
] | [] | [] | [] | Enhanced | Supported | null | 61 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 45: Non-specific - Mixed function | Cluster 66: Non-specific - Mitochondria | Cluster 97: Non-specific - Cellular respiration | Cluster 52: Non-specific - Cellular respiration | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [] | [
"Head and Neck Squamous Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 2,197 | 4 |
ENSG00000100218 | RSPH14 | Radial spoke head 14 homolog | [
"Q9UHP6"
] | 22 | 23059415-23145021 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA018420",
"HPA050425"
] | [
"RTDR1"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoli"
] | [] | [] | [] | Uncertain | Approved | null | 42 | null | null | Cluster 4: Neutrophils - Degranulation | Cluster 17: Choroid plexus - Cilium | Cluster 15: Kidney cancer - Membrane components | Cluster 107: Ciliated cells - Cilia assembly & function | Cluster 48: Ciliated tissues - Cilium organization | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in some | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in some | 4 | 3 | 0 | 3 | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 2,198 | 3 |
ENSG00000100219 | XBP1 | X-box binding protein 1 | [
"P17861"
] | 22 | 28794555-28800597 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"XBP2"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transcription factors"
] | [
"Angiogenesis",
"Apoptosis",
"Autophagy",
"Differentiation",
"Lipid biosynthesis",
"Lipid metabolism",
"Myogenesis",
"Protein transport",
"Stress response",
"Transcription",
"Transcription regulation",
"Transport",
"Unfolded protein response"
] | [
"Activator",
"Developmental protein",
"DNA-binding"
] | [
"Cancer-related genes",
"Oncogene"
] | [] | [] | [] | [] | null | null | null | 7 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 21: Non-specific - Metabolism | Cluster 27: Breast cancer - Unknown function | Cluster 44: Plasma cells - Antibody production & secretion | Cluster 8: Pancreas - Proteolysis | Tissue enhanced | Detected in all | null | Cancer enhanced | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Colon Adenocarcinoma"
] | [] | [
"Colon Adenocarcinoma"
] | 2,199 | 3 |
ENSG00000100220 | RTCB | RNA 2',3'-cyclic phosphate and 5'-OH ligase | [
"Q9Y3I0"
] | 22 | 32387582-32412248 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000535",
"HPA001103"
] | [
"C22orf28",
"FAAP",
"HSPC117"
] | [
"Enzymes",
"Essential proteins",
"Predicted intracellular proteins"
] | [
"tRNA processing"
] | [
"Ligase"
] | [] | [
"Nucleoplasm"
] | [
"Vesicles",
"Cytosol"
] | [] | [] | Supported | Supported | null | 75 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 27: Non-specific - Mixed function | Cluster 66: Non-specific - Mitochondria | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 2,200 | 7 |
ENSG00000100221 | JOSD1 | Josephin domain containing 1 | [
"Q15040"
] | 22 | 38685543-38701556 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA001168",
"CAB034927"
] | [
"KIAA0063"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [
"Hydrolase",
"Protease"
] | [] | [
"Vesicles",
"Cytosol"
] | [] | [] | [] | Approved | Uncertain | null | 28 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 34: Non-specific - Mixed function | Cluster 66: Non-specific - Mitochondria | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 15: Bone marrow - Innate immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Rectum Adenocarcinoma"
] | 2,201 | 3 |
ENSG00000100225 | FBXO7 | F-box protein 7 | [
"Q9Y3I1"
] | 22 | 32474676-32498829 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA032113",
"HPA032114",
"CAB034296",
"HPA057352"
] | [
"Fbx",
"FBX7",
"PARK15"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [] | [
"Disease variant",
"Neurodegeneration",
"Parkinson disease",
"Parkinsonism"
] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | [] | Supported | Uncertain | null | 99 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 28: Oligodendrocytes - Mixed function | Cluster 69: Skin cancer - ECM organization | Cluster 66: Erythroid cells - Erythroid differentiation and maturation | Cluster 44: Bone marrow - Nuclear processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 2,202 | 6 |
ENSG00000100226 | GTPBP1 | GTP binding protein 1 | [
"O00178"
] | 22 | 38705742-38738299 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003166",
"HPA064702"
] | [
"GP-1",
"HSPC018"
] | [
"Predicted intracellular proteins"
] | [] | [] | [
"Intellectual disability"
] | [
"Golgi apparatus",
"Cytosol"
] | [
"Nuclear bodies"
] | [] | [] | Approved | Approved | null | 15 | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 55: Non-specific - Transcription | Cluster 66: Non-specific - Mitochondria | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 15: Bone marrow - Innate immune response | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in all | 4 | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Rectum Adenocarcinoma"
] | [] | [
"Rectum Adenocarcinoma"
] | 2,203 | 9 |
ENSG00000100227 | POLDIP3 | DNA polymerase delta interacting protein 3 | [
"Q9BY77"
] | 22 | 42583721-42614962 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA018419",
"HPA048790"
] | [
"KIAA1649",
"PDIP3",
"PDIP46",
"SKAR"
] | [
"Predicted intracellular proteins"
] | [
"mRNA transport",
"Translation regulation",
"Transport"
] | [
"RNA-binding"
] | [] | [
"Nuclear speckles"
] | [
"Cytoplasmic bodies"
] | [] | [] | Enhanced | Approved | null | 27 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 13: Oligodendrocytes - Mixed function | Cluster 66: Non-specific - Mitochondria | Cluster 102: Non-specific - Mixed function | Cluster 54: Non-specific - Ribosome | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 2,204 | 6 |
ENSG00000100228 | RAB36 | RAB36, member RAS oncogene family | [
"O95755"
] | 22 | 23145366-23165663 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA059631"
] | [] | [
"Predicted intracellular proteins"
] | [
"Protein transport",
"Transport"
] | [
"Hydrolase"
] | [] | [
"Vesicles"
] | [] | [] | [] | Uncertain | null | null | 1 | null | null | Cluster 4: Neutrophils - Degranulation | Cluster 17: Choroid plexus - Cilium | Cluster 51: Myeloma - Immunoglobulins | Cluster 107: Ciliated cells - Cilia assembly & function | Cluster 48: Ciliated tissues - Cilium organization | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in some | 8 | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 2,205 | 5 |
ENSG00000100234 | TIMP3 | TIMP metallopeptidase inhibitor 3 | [
"P35625"
] | 22 | 32801705-32863041 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA068391"
] | [
"SFD"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Predicted secreted proteins"
] | [
"Sensory transduction",
"Vision"
] | [
"Metalloenzyme inhibitor",
"Metalloprotease inhibitor",
"Protease inhibitor"
] | [
"Cancer-related genes",
"Disease variant"
] | [
"Vesicles"
] | [
"Golgi apparatus"
] | [
"Secreted to extracellular matrix"
] | [
"Enzyme inhibitor"
] | Approved | null | null | 20 | null | null | null | Cluster 42: Choroid plexus - Mitochondria | Cluster 64: Connective tissue cells - ECM organization | Cluster 110: Mural cells - ECM organization | Cluster 14: Adipose tissue - Angiogenesis | Low tissue specificity | Detected in all | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 4 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 2,206 | 8 |
ENSG00000100239 | PPP6R2 | Protein phosphatase 6 regulatory subunit 2 | [
"O75170"
] | 22 | 50343304-50445090 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA030656",
"HPA075438"
] | [
"dJ579N16.1",
"KIAA0685",
"SAP190",
"SAPS2"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Cytosol"
] | [
"Cytoplasmic bodies"
] | [] | [] | Supported | Approved | null | 22 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 32: Cerebral cortex - Mixed function | Cluster 66: Non-specific - Mitochondria | Cluster 7: Non-specific - Transcription | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Papillary Cell Carcinoma"
] | 2,207 | 9 |
ENSG00000100241 | SBF1 | SET binding factor 1 | [
"O95248"
] | 22 | 50443219-50483923 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA074004"
] | [
"DENND7A",
"MTMR5"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [
"Guanine-nucleotide releasing factor"
] | [
"Charcot-Marie-Tooth disease",
"Disease variant",
"Neurodegeneration",
"Neuropathy"
] | [
"Nuclear bodies"
] | [] | [] | [] | Supported | null | null | 21 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 32: Cerebral cortex - Mixed function | Cluster 66: Non-specific - Mitochondria | Cluster 53: Late primary spermatocytes - Meiotic division & transition | Cluster 78: Brain - Neuronal signaling | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 2,208 | 6 |
ENSG00000100242 | SUN2 | Sad1 and UNC84 domain containing 2 | [
"Q9UH99"
] | 22 | 38733290-38794143 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001209"
] | [
"UNC84B"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Meiosis"
] | [] | [] | [
"Nuclear membrane"
] | [] | [] | [] | Supported | Supported | null | 74 | null | Yes | Cluster 3: Non-specific - Nuclear processes | Cluster 11: White matter - Signal transduction | Cluster 6: Leukemia - Signal transduction | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 2,209 | 1 |
ENSG00000100243 | CYB5R3 | Cytochrome b5 reductase 3 | [
"P00387"
] | 22 | 42615730-42720870 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001566"
] | [
"DIA1"
] | [
"Cancer-related genes",
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Cholesterol biosynthesis",
"Cholesterol metabolism",
"Lipid biosynthesis",
"Lipid metabolism",
"Steroid biosynthesis",
"Steroid metabolism",
"Sterol biosynthesis",
"Sterol metabolism"
] | [
"Oxidoreductase"
] | [
"Cancer-related genes",
"Disease variant"
] | [
"Endoplasmic reticulum"
] | [
"Perinuclear theca",
"Calyx",
"Connecting piece",
"Mid piece",
"Principal piece"
] | [] | [] | Supported | Approved | null | 98 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 20: Macrophages & Microglia - Immune response | Cluster 64: Connective tissue cells - ECM organization | Cluster 100: Stratified epithelial cells - Barrier functions | Cluster 12: Smooth muscle tissue - ECM organization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 2,210 | 6 |
ENSG00000100249 | C22orf31 | Chromosome 22 open reading frame 31 | [
"O95567"
] | 22 | 29058672-29061831 | Evidence at transcript level | Evidence at transcript level | Evidence at transcript level | Evidence at transcript level | [
"HPA000604",
"HPA068522"
] | [
"bK747E2.1",
"HS747E2A"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nuclear membrane"
] | [
"Cytosol"
] | [] | [] | Approved | Uncertain | null | null | null | null | null | Cluster 15: Non-specific - Transcription | Cluster 32: Non-specific - Cell proliferation | Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase | Cluster 67: Testis - Mixed function | Group enriched | Detected in some | 4 | Cancer enriched | Detected in single | 7 | Not detected | Not detected | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 2,212 | 9 |
ENSG00000100253 | MIOX | Myo-inositol oxygenase | [
"Q9UGB7"
] | 22 | 50486784-50490648 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA039451",
"HPA039562"
] | [
"ALDRL6"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [
"Oxidoreductase"
] | [] | [] | [] | [] | [] | null | Enhanced | null | 8 | null | null | null | Cluster 48: Non-specific - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 88: Proximal tubular cells - Transmembrane transport | Cluster 72: Kidney - Transmembrane transport | Tissue enriched | Detected in some | 47 | Cancer enhanced | Detected in some | null | Group enriched | Detected in many | 19 | Cell type enriched | Detected in some | 14 | Not detected in immune cells | Not detected | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 2,213 | 3 |
ENSG00000100258 | LMF2 | Lipase maturation factor 2 | [
"Q9BU23"
] | 22 | 50502949-50507702 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA062626"
] | [
"TMEM112B",
"TMEM153"
] | [
"Predicted membrane proteins"
] | [] | [] | [] | [
"Centrosome"
] | [] | [] | [] | Approved | Approved | null | 6 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 44: Non-specific - Mixed function | Cluster 66: Non-specific - Mitochondria | Cluster 63: Cytotrophoblasts - Basic cellular functions | Cluster 70: Non-specific - Protein processing | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Ovary Serous Cystadenocarcinoma"
] | [] | [
"Ovary Serous Cystadenocarcinoma"
] | 2,214 | 9 |
ENSG00000100263 | RHBDD3 | Rhomboid domain containing 3 | [
"Q9Y3P4"
] | 22 | 29259872-29268209 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA043979"
] | [
"C22orf3",
"PTAG"
] | [
"Predicted membrane proteins"
] | [] | [] | [] | [
"Microtubules"
] | [] | [] | [] | Approved | Approved | null | 1 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 41: Monoamines - Neurotransmitter signalling | Cluster 66: Non-specific - Mitochondria | Cluster 63: Cytotrophoblasts - Basic cellular functions | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 2 | 1 | [
"Lung Squamous Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 2,215 | 5 |
ENSG00000100266 | PACSIN2 | Protein kinase C and casein kinase substrate in neurons 2 | [
"Q9UNF0"
] | 22 | 42835412-43015149 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA049854",
"HPA056520"
] | [
"SDPII"
] | [
"Predicted intracellular proteins"
] | [
"Endocytosis"
] | [] | [] | [
"Nuclear speckles",
"Plasma membrane"
] | [
"Vesicles",
"Primary cilium",
"Centriolar satellite"
] | [] | [] | Approved | Enhanced | null | 48 | null | null | Cluster 7: Non-specific - Innate immune response | Cluster 49: Hindbrain - Mixed function | Cluster 9: Skin cancer - Melanin biosynthesis | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 8: Pancreas - Proteolysis | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Immune cell enhanced | Detected in all | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 2,216 | 8 |
ENSG00000100271 | TTLL1 | TTL family tubulin polyglutamylase complex subunit L1 | [
"O95922"
] | 22 | 43039516-43089419 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA048392"
] | [
"C22orf7",
"PGs3",
"TPGS3"
] | [
"Predicted intracellular proteins"
] | [] | [
"Ligase"
] | [] | [] | [] | [] | [] | null | Approved | null | 1 | null | No | Cluster 5: Non-specific - Cell proliferation | Cluster 14: Neurons - Synaptic function | Cluster 66: Non-specific - Mitochondria | Cluster 33: Early spermatids - Spermiogenesis: Cap phase | Cluster 48: Ciliated tissues - Cilium organization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 2,217 | 8 |
ENSG00000100276 | RASL10A | RAS like family 10 member A | [
"Q92737"
] | 22 | 29312933-29319679 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA056169"
] | [
"RRP22"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase"
] | [
"Tumor suppressor"
] | [] | [] | [] | [] | null | Approved | null | null | null | null | null | Cluster 51: Neurons - Mixed function | Cluster 72: Neuronal - Signal transduction | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 78: Brain - Neuronal signaling | Tissue enriched | Detected in many | 8 | Not detected | Not detected | null | Group enriched | Detected in some | 5 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Glioblastoma Multiforme"
] | [] | [
"Glioblastoma Multiforme"
] | 2,218 | 2 |
ENSG00000100280 | AP1B1 | Adaptor related protein complex 1 subunit beta 1 | [
"Q10567"
] | 22 | 29327680-29388583 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA065226",
"HPA068520"
] | [
"ADTB1",
"AP105A",
"BAM22",
"CLAPB2"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Transporters"
] | [
"Protein transport",
"Transport"
] | [] | [
"Deafness",
"Disease variant",
"Ichthyosis"
] | [
"Golgi apparatus"
] | [
"Vesicles",
"Cytosol"
] | [] | [] | Supported | Approved | null | 41 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 38: Sub-cortical - Mixed function | Cluster 66: Non-specific - Mitochondria | Cluster 87: B-cells - Adaptive immunity: Humoral response | Cluster 11: Esophagus - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 2,219 | 4 |
ENSG00000100281 | HMGXB4 | HMG-box containing 4 | [
"Q9UGU5"
] | 22 | 35257452-35295807 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA000725",
"HPA076681"
] | [
"HMG2L1",
"P53N",
"THC211630"
] | [
"Cancer-related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Wnt signaling pathway"
] | [
"DNA-binding"
] | [
"Cancer-related genes"
] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Approved | null | 26 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 28: Oligodendrocytes - Mixed function | Cluster 66: Non-specific - Mitochondria | Cluster 27: Non-specific - Cell proliferation | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Rectum Adenocarcinoma"
] | [
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma",
"Rectum Adenocarcinoma"
] | 2,220 | 8 |
ENSG00000100284 | TOM1 | Target of myb1 membrane trafficking protein | [
"O60784"
] | 22 | 35299275-35347992 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001749"
] | [] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins",
"Transporters"
] | [
"Protein transport",
"Transport"
] | [] | [
"Cancer-related genes",
"Disease variant"
] | [
"Cytosol"
] | [
"Golgi apparatus"
] | [] | [] | Supported | Approved | null | 22 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 49: Hindbrain - Mixed function | Cluster 66: Non-specific - Mitochondria | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 24: Non-specific - Transcription | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 2,221 | 1 |
ENSG00000100285 | NEFH | Neurofilament heavy chain | [
"P12036"
] | 22 | 29480218-29491390 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB007786",
"HPA061615"
] | [
"NF-H",
"NFH"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [] | [
"Amyotrophic lateral sclerosis",
"Charcot-Marie-Tooth disease",
"Disease variant",
"Neurodegeneration",
"Neuropathy"
] | [
"Nuclear bodies",
"Centrosome",
"Basal body"
] | [
"Nucleoplasm",
"Primary cilium",
"Primary cilium transition zone",
"Cytosol"
] | [] | [] | Approved | Enhanced | null | 4 | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 45: Non-specific - Mixed function | Cluster 10: Ciliated cells - Ion channel activity | Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid | Cluster 65: Brain - Transcription | Group enriched | Detected in some | 4 | Cancer enhanced | Detected in many | null | Group enriched | Detected in many | 6 | Cell type enriched | Detected in many | 34 | Immune cell enhanced | Detected in some | null | 1 | 0 | 1 | [
"Breast Invasive Carcinoma"
] | [] | [
"Breast Invasive Carcinoma"
] | 2,222 | 1 |
ENSG00000100288 | CHKB | Choline kinase beta | [
"Q9Y259"
] | 22 | 50578959-50601455 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA018797"
] | [
"CHETK",
"CHKL"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Lipid biosynthesis",
"Lipid metabolism",
"Phospholipid biosynthesis",
"Phospholipid metabolism"
] | [
"Kinase",
"Transferase"
] | [
"Congenital muscular dystrophy",
"Disease variant"
] | [
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | null | null | null | Cluster 29: Non-specific - Unknown function | Cluster 21: Non-specific - Metabolism | Cluster 24: Non-specific - Unknown function | Cluster 98: Neurons - Neurotransmission & signaling | Cluster 21: Testis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Glioblastoma Multiforme",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 2,223 | 7 |
ENSG00000100290 | BIK | BCL2 interacting killer | [
"Q13323"
] | 22 | 43110750-43129712 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA051360"
] | [
"NBK"
] | [
"Predicted membrane proteins"
] | [
"Apoptosis"
] | [] | [] | [] | [] | [] | [] | null | Approved | null | 91 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 15: Non-specific - Transcription | Cluster 46: Lymphoma - Humoral immune response | Cluster 95: Tuft cells - Chemosensory signaling | Cluster 11: Esophagus - Basic cellular processes | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 1 | 0 | 1 | [] | [
"Breast Invasive Carcinoma"
] | [
"Breast Invasive Carcinoma"
] | 2,224 | 1 |
ENSG00000100292 | HMOX1 | Heme oxygenase 1 | [
"P09601"
] | 22 | 35380361-35394214 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000635",
"CAB017444"
] | [
"bK286B10",
"HO-1"
] | [
"Cancer-related genes",
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Apoptosis",
"Host-virus interaction"
] | [
"Oxidoreductase"
] | [
"Cancer-related genes"
] | [
"Golgi apparatus",
"Plasma membrane"
] | [] | [] | [] | Uncertain | Enhanced | null | 45 | null | null | Cluster 40: Monocytes - Innate immune response | Cluster 12: Non-specific - Vasculature | Cluster 7: Liver cancer - Metabolism | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 66: Lymphoid tissue - Immune response | Tissue enriched | Detected in all | 5 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 5 | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 2,225 | 3 |
ENSG00000100297 | MCM5 | Minichromosome maintenance complex component 5 | [
"P33992"
] | 22 | 35400134-35425431 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB000101",
"HPA000845",
"HPA052880"
] | [
"CDC46"
] | [
"Cancer-related genes",
"Disease related genes",
"Enzymes",
"Essential proteins",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"DNA replication"
] | [
"DNA-binding",
"Helicase",
"Hydrolase"
] | [
"Cancer-related genes",
"Disease variant",
"Dwarfism"
] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Enhanced | null | 76 | Yes | Yes | Cluster 23: B-cells - Immunoglobulins | Cluster 30: White matter - Myelination | Cluster 66: Non-specific - Mitochondria | Cluster 63: Cytotrophoblasts - Basic cellular functions | Cluster 44: Bone marrow - Nuclear processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 2,228 | 4 |
ENSG00000100298 | APOBEC3H | Apolipoprotein B mRNA editing enzyme catalytic subunit 3H | [
"Q6NTF7"
] | 22 | 39097224-39104067 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA021492",
"HPA058565"
] | [
"ARP10"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Antiviral defense",
"Immunity",
"Innate immunity"
] | [
"Hydrolase"
] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | Approved | null | null | null | null | Cluster 1: T-cells - Unknown function | Cluster 15: Non-specific - Transcription | Cluster 55: Lymphoma - Immune response | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 18: Lymphoid tissue - Immune response | Low tissue specificity | Detected in many | null | Group enriched | Detected in some | 4 | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in some | null | Group enriched | Detected in many | 9 | 2 | 0 | 2 | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 2,229 | 9 |
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