LiteFold/InterPro · Datasets at Hugging Face

IPR021850

21,850

Symplekin/Pta1

Family

4,457

false

Proteins in this entry include Symplekin from animals and Pta1 from yeasts. Symplekin is a scaffold protein that functions as a component of a multimolecular complex involved in histone mRNA 3'-end processing [ , ]. Pta1 is involved in pre-tRNA processing. Pta1 is a subunit of the cleavage and polyadenylation factor (C...

[]

0

[ "PANTHER" ]

[ "PTHR15245" ]

[ "" ]

[ 4457 ]

1

[ "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME" ]

[ "R-DME-159231", "R-DME-72187", "R-DME-72203", "R-DME-73856", "R-DME-77595", "R-HSA-159231", "R-HSA-72187", "R-HSA-72203", "R-HSA-73856", "R-HSA-77595", "R-MMU-159231", "R-MMU-72187", "R-MMU-72203", "R-MMU-73856", "R-MMU-77595", "R-SCE-77595", "R-SPO-159231", "R-SPO-77595" ]

[ "REACTOME:R-DME-159231", "REACTOME:R-DME-72187", "REACTOME:R-DME-72203", "REACTOME:R-DME-73856", "REACTOME:R-DME-77595", "REACTOME:R-HSA-159231", "REACTOME:R-HSA-72187", "REACTOME:R-HSA-72203", "REACTOME:R-HSA-73856", "REACTOME:R-HSA-77595", "REACTOME:R-MMU-159231", "REACTOME:R-MMU-72187", "...

18

[ "3gs3", "3o2q", "3o2s", "3o2t", "3odr", "3ods", "4h3h", "4h3k", "4imi", "4imj", "4ygx", "6npw", "6v4x" ]

13

[ "PUB00068954", "PUB00068955", "PUB00070276" ]

[ "18042462", "19450530", "12819204" ]

[ "A genome-wide RNA interference screen reveals that variant histones are necessary for replication-dependent histone pre-mRNA processing.", "A core complex of CPSF73, CPSF100, and Symplekin may form two different cleavage factors for processing of poly(A) and histone mRNAs.", "Organization and function of APT, ...

[ 2007, 2009, 2003 ]

3

[]

0

null

[ "Eukaryota" ]

[ 4457 ]

1

[ "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Homo sapiens", "Mus musculus", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Rattus norvegicus", "Saccharomyces cerevisiae (strain ATCC 204508 / S288c)", "Schizosaccharomyces pombe (strai...

[ 1, 2, 1, 10, 8, 1, 5, 1, 2 ]

9

true

Family

Symplekin/Pta1

8

IPR021851

21,851

Protein of unknown function DUF3455

DUF3455

Family

5,074

false

This family of proteins are functionally uncharacterised. This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 174 to 251 amino acids in length.

[]

0

[ "PFAM" ]

[ "PF11937" ]

[ "DUF3455" ]

[ 5074 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Eukaryota", "metagenomes" ]

[ 1931, 3136, 7 ]

3

[ "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)" ]

[ 2 ]

1

true

Family

Protein of unknown function DUF3455

DUF3455

4

IPR021852

21,852

Domain of unknown function DUF3456

DUF3456

Domain

7,023

false

This presumed domain is functionally uncharacterised. It is found in a number of proteins, including protein canopy homologues and CRELD1 and 2.

[]

0

[ "PFAM" ]

[ "PF11938" ]

[ "DUF3456" ]

[ 7023 ]

1

[ "REACTOME", "REACTOME", "REACTOME", "REACTOME" ]

[ "R-BTA-1679131", "R-HSA-1679131", "R-MMU-1679131", "R-SSC-1679131" ]

[ "REACTOME:R-BTA-1679131", "REACTOME:R-HSA-1679131", "REACTOME:R-MMU-1679131", "REACTOME:R-SSC-1679131" ]

4

[ "7aah" ]

1

[]

0

[]

0

null

[ "Eukaryota", "bird metagenome" ]

[ 7021, 2 ]

2

[ "Arabidopsis thaliana", "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Homo sapiens", "Mus musculus", "Oryza sativa subsp. japonica", "Rattus norvegicus", "Zea mays" ]

[ 7, 4, 8, 3, 35, 14, 2, 19, 8 ]

9

true

Domain

Domain of unknown function DUF3456

DUF3456

2

IPR021853

21,853

Protein of unknown function DUF3460

DUF3460

Family

1,430

false

This family of proteins are functionally uncharacterised. This protein is found in bacteria. Proteins in this family are about 70 amino acids in length. This protein has a conserved WDK sequence motif.

[]

0

[ "PFAM" ]

[ "PF11943" ]

[ "DUF3460" ]

[ 1430 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Eukaryota", "metagenomes" ]

[ 1416, 3, 11 ]

3

[]

0

true

Family

Protein of unknown function DUF3460

DUF3460

8

IPR021854

21,854

WASH1, WAHD domain

WASH1_WAHD

Domain

2,137

false

This entry represents the N-terminal WAHD domain (N-terminal WASH homology regions) of the WASH1 protein, which is a component of the WASH complex that is present at the surface of endosomes and activates the Arp2/3-mediated F-actin polymerisation [ ]. This domain covers the conserved WHD1/EVH1 and WHD2 domains. WASH1 ...

[]

0

[ "PFAM" ]

[ "PF11945" ]

[ "WASH_WAHD" ]

[ 2137 ]

1

[ "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME" ]

[ "R-CEL-2029482", "R-CEL-5663213", "R-DDI-2029482", "R-DDI-5663213", "R-DME-2029482", "R-DME-5663213" ]

[ "REACTOME:R-CEL-2029482", "REACTOME:R-CEL-5663213", "REACTOME:R-DDI-2029482", "REACTOME:R-DDI-5663213", "REACTOME:R-DME-2029482", "REACTOME:R-DME-5663213" ]

6

[]

0

[ "PUB00054152", "PUB00057271" ]

[ "19922875", "19922874" ]

[ "The Arp2/3 activator WASH controls the fission of endosomes through a large multiprotein complex.", "A FAM21-containing WASH complex regulates retromer-dependent sorting." ]

[ 2009, 2009 ]

2

[]

0

null

[ "Aeribacillus pallidus", "Eukaryota" ]

[ 1, 2136 ]

2

[ "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Homo sapiens", "Mus musculus", "Oryza sativa subsp. japonica", "Rattus norvegicus" ]

[ 1, 2, 12, 33, 2, 3, 7 ]

7

true

Domain

WASH1, WAHD domain

WASH1_WAHD

1

IPR021855

21,855

PAM68-like

Family

1,545

false

This entry includes chloroplastic protein PAM68 and some uncharacterised proteins from Cyanobacteria (blue-green algae). PAM68 is involved in early steps in photosystem II (PSII) biogenesis and in maturation and stability of newly synthesized psbA protein [ ].

[]

0

[ "PFAM", "PANTHER" ]

[ "PF11947", "PTHR34575" ]

[ "DUF3464", "" ]

[ 1543, 1489 ]

2

[]

0

[]

0

[ "PUB00086018" ]

[ "20923938" ]

[ "The Arabidopsis thylakoid protein PAM68 is required for efficient D1 biogenesis and photosystem II assembly." ]

[ 2010 ]

1

[]

0

null

[ "Bacteria", "Eukaryota" ]

[ 363, 1182 ]

2

[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 7, 8, 9 ]

3

true

Family

PAM68-like

7

IPR021856

21,856

Protein of unknown function DUF3465

DUF3465

Family

905

false

This family of proteins are functionally uncharacterised. This protein is found in bacteria. Proteins in this family are typically between 131 to 151 amino acids in length. This protein has a conserved HWTH sequence motif.

[]

0

[ "PFAM" ]

[ "PF11948" ]

[ "DUF3465" ]

[ 905 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "ecological metagenomes" ]

[ 894, 11 ]

2

[]

0

true

Family

Protein of unknown function DUF3465

DUF3465

7

IPR021859

21,859

XRN2-binding (XTBD) domain

XTBD

Domain

2,749

false

XRN2 is an essential eukaryotic exoribonuclease that processes and degrades various substrates. The ~80-residue XRN2-binding domain (XTBD) constitutes an XRN2-binding module that is employed by different metazoan proteins to link to XRN2 [ , ], such as: Caenorhabditis elegans Partner of Xrn-Two protein 1, or PAXT-1 for...

[]

0

[ "PFAM", "PROFILE" ]

[ "PF11952", "PS51827" ]

[ "XTBD", "XTBD" ]

[ 2697, 2721 ]

2

[]

0

[ "5fir" ]

1

[ "PUB00075685", "PUB00087111", "PUB00087114", "PUB00087115" ]

[ "24462208", "26779609", "15109303", "24825908" ]

[ "PAXT-1 promotes XRN2 activity by stabilizing it through a conserved domain.", "Structural basis and function of XRN2 binding by XTB domains.", "Alternative reading frame protein (ARF)-independent function of CARF (collaborator of ARF) involves its interactions with p53: evidence for a novel p53-activation path...

[ 2014, 2016, 2004, 2014 ]

4

[]

0

null

[ "Eukaryota", "Imitervirales", "Loktanella fryxellensis", "metagenomes" ]

[ 2735, 3, 1, 10 ]

4

[ "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Homo sapiens", "Mus musculus", "Rattus norvegicus" ]

[ 1, 11, 1, 7, 5, 7 ]

6

true

Domain

XRN2-binding (XTBD) domain

XTBD

1

IPR021860

21,860

Peptidase S12, Pab87-related, C-terminal

Peptidase_S12_Pab87-rel_C

Domain

6,890

false

This entry represents the C-terminal domain of a family of peptidases which belong to MEROPS peptidase family S12, clan SE. The structure of the Pyrococcus abyssi Pab87 peptidase has been determined at 2.2 A resolution [ ]. Pab87 is a self-compartmentalizing proteases that orchestrates protein turnover through an origi...

[]

0

[ "PFAM" ]

[ "PF11954" ]

[ "DUF3471" ]

[ 6890 ]

1

[]

0

[ "4whi" ]

1

[ "PUB00049065", "PUB00152844" ]

[ "19266066", "36715406" ]

[ "Structure of the archaeal pab87 peptidase reveals a novel self-compartmentalizing protease family.", "Biosynthetic Characterization, Heterologous Production, and Genomics-Guided Discovery of GABA-Containing Fungal Heptapeptides." ]

[ 2009, 2023 ]

2

[]

0

null

[ "Archaea", "Bacteria", "Eukaryota", "unclassified sequences" ]

[ 22, 5222, 1596, 50 ]

4

[]

0

true

Domain

Peptidase S12, Pab87-related, C-terminal

Peptidase_S12_Pab87-rel_C

8

IPR021861

21,861

THO complex, subunit THOC1

THO_THOC1

Family

5,422

false

THO complex subunit 1 (THOC1; its homologues from plants and yeast HPR1) is a component of the THO subcomplex of the TREX complex, which is involved in coupling mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX plays central roles duri...

[]

0

[ "PFAM", "PANTHER" ]

[ "PF11957", "PTHR13265" ]

[ "efThoc1", "" ]

[ 4864, 5132 ]

2

[ "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME" ]

[ "R-HSA-159236", "R-HSA-72187", "R-HSA-73856", "R-MMU-159236", "R-MMU-72187", "R-MMU-73856" ]

[ "REACTOME:R-HSA-159236", "REACTOME:R-HSA-72187", "REACTOME:R-HSA-73856", "REACTOME:R-MMU-159236", "REACTOME:R-MMU-72187", "REACTOME:R-MMU-73856" ]

6

[ "7apk", "7apx", "7aqo", "7luv", "7v2w", "7v2y", "7znk", "7znl", "8r7l" ]

9

[ "PUB00063152", "PUB00100460", "PUB00100461", "PUB00100462" ]

[ "14527416", "33191911", "33787496", "22035198" ]

[ "Cotranscriptionally formed DNA:RNA hybrids mediate transcription elongation impairment and transcription-associated recombination.", "Structure of the human core transcription-export complex reveals a hub for multivalent interactions.", "Cryo-EM structure of the yeast TREX complex and coordination with the SR-...

[ 2003, 2020, 2021, 2012 ]

4

[]

0

null

[ "Eukaryota" ]

[ 5422 ]

1

[ "Arabidopsis thaliana", "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Homo sapiens", "Mus musculus", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Oryza sativa subsp. japonica", "Rattus norvegicus", "Saccharomyces cerevisiae (strai...

[ 8, 1, 6, 1, 4, 3, 1, 5, 8, 1, 1, 4 ]

12

true

Family

THO complex, subunit THOC1

THO_THOC1

8

IPR021862

21,862

Surface attachment protein BPSS1860

BPSS1860

Family

1,902

false

This entry represents Surface attachment protein BP1026B_II1992. This protein is required for infection of the mammalian host cells and complete B.pseudomallei pathogenesis in vivo. Attaches to host cells [ ]. This entry includes Surface attachment protein BPSS1860 which is required for infection of the mammalian host ...

[]

0

[ "PFAM" ]

[ "PF11958" ]

[ "DUF3472" ]

[ 1902 ]

1

[]

0

[ "4qhw", "4qhx", "8pmu", "8pn3", "8pn5" ]

5

[ "PUB00159059" ]

[ "33772012" ]

[ "The Burkholderia pseudomallei intracellular 'TRANSITome'." ]

[ 2021 ]

1

[]

0

null

[ "Bacteria", "Eukaryota", "metagenomes" ]

[ 1544, 337, 21 ]

3

[ "Drosophila melanogaster" ]

[ 1 ]

1

true

Family

Surface attachment protein BPSS1860

BPSS1860

2

IPR021863

21,863

Fatty acid desaturase, N-terminal

FAS_N

Domain

5,199

false

This domain is found in fatty acid desaturases (FADs), mainly from plants and fungi.

[ "GO:0016717" ]

[ "oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water" ]

[ "molecular_function" ]

1

[ "PFAM" ]

[ "PF11960" ]

[ "DUF3474" ]

[ 5199 ]

1

[ "EC", "GP", "GP", "GP" ]

[ "1.14.19", "GenProp1339", "GenProp1690", "GenProp1761" ]

[ "EC:1.14.19", "GP:GenProp1339", "GP:GenProp1690", "GP:GenProp1761" ]

4

[]

0

[]

0

[]

0

null

[ "Cyanophyceae", "Eukaryota" ]

[ 56, 5143 ]

2

[ "Arabidopsis thaliana", "Caenorhabditis elegans", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 19, 1, 1, 19, 41 ]

5

true

Domain

Fatty acid desaturase, N-terminal

FAS_N

4

IPR021864

21,864

Domain of unknown function DUF3475

DUF3475

Domain

5,816

false

This entry represents the N-terminal domain of PSI proteins from Arabidopsis. This domain is found associated with DUF668 ( ). PSI1 was identified as a gene that is co-expressed with the phytosulfokine (PSK) receptor genes PSKR1 and PSKR2 in Arabidopsis thaliana. PSI proteins are plant-specific and promote growth [ ].

[ "GO:0045927" ]

[ "positive regulation of growth" ]

[ "biological_process" ]

1

[ "PFAM" ]

[ "PF11961" ]

[ "DUF3475" ]

[ 5816 ]

1

[]

0

[]

0

[ "PUB00093967" ]

[ "25062973" ]

[ "The PSI family of nuclear proteins is required for growth in arabidopsis." ]

[ 2014 ]

1

[]

0

null

[ "Streptophyta" ]

[ 5816 ]

1

[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 30, 40, 73 ]

3

true

Domain

Domain of unknown function DUF3475

DUF3475

3

IPR021866

21,866

SpoIIAA-like

Family

5,809

false

These proteins adopt an α/β SpoIIAA-like fold, similar to that found in STAT . They adopt open and closed conformations arising from different arrangements of their α2 and α3 helices. They may be membrane associated and may function as carriers of non-polar compounds [ ].

[]

0

[ "PFAM" ]

[ "PF11964" ]

[ "SpoIIAA-like" ]

[ 5809 ]

1

[]

0

[ "2ook", "2q3l" ]

2

[ "PUB00066715" ]

[ "20944218" ]

[ "Open and closed conformations of two SpoIIAA-like proteins (YP_749275.1 and YP_001095227.1) provide insights into membrane association and ligand binding." ]

[ 2010 ]

1

[]

0

null

[ "Aureococcus anophagefferens virus", "Bacteria", "Eukaryota", "Methanobacteriota", "unclassified sequences" ]

[ 1, 5589, 6, 150, 63 ]

5

[]

0

true

Family

SpoIIAA-like

7

IPR021867

21,867

S-adenosylmethionine-dependent methyltransferase Bmt2-like

Bmt2/SAMTOR

Family

3,308

false

This entry includes Bmt2 from yeasts and SAMTOR from animals. They contain a class I Rossmann fold methyltransferase domain. In Saccharomyces cerevisiae, Bmt2 is a nucleolar S-adenosylmethionine-dependent rRNA methyltransferase that is responsible for the N-1-methyl-adenosine base modification of 25S rRNA [ ]. It speci...

[]

0

[ "HAMAP", "PFAM", "PANTHER" ]

[ "MF_03044", "PF11968", "PTHR21008" ]

[ "BMT2", "Bmt2", "" ]

[ 2823, 2742, 3242 ]

3

[ "EC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC"...

[ "2.1.1.-", "PWY-1061", "PWY-2083", "PWY-3542", "PWY-4021", "PWY-4161", "PWY-4202", "PWY-5059", "PWY-5105", "PWY-5301", "PWY-5305", "PWY-5479", "PWY-5665", "PWY-5729", "PWY-5748", "PWY-5765", "PWY-5773", "PWY-5846", "PWY-5883", "PWY-5975", "PWY-5987", "PWY-601", "PWY-6045"...

[ "EC:2.1.1.-", "METACYC:PWY-1061", "METACYC:PWY-2083", "METACYC:PWY-3542", "METACYC:PWY-4021", "METACYC:PWY-4161", "METACYC:PWY-4202", "METACYC:PWY-5059", "METACYC:PWY-5105", "METACYC:PWY-5301", "METACYC:PWY-5305", "METACYC:PWY-5479", "METACYC:PWY-5665", "METACYC:PWY-5729", "METACYC:PWY-5...

149

[ "7vkk", "7vkq", "7vkr", "7yri", "7yrj", "8gmy", "8gmz" ]

7

[ "PUB00066965", "PUB00088163" ]

[ "23558746", "29123071" ]

[ "Identification of a novel methyltransferase, Bmt2, responsible for the N-1-methyl-adenosine base modification of 25S rRNA in Saccharomyces cerevisiae.", "SAMTOR is an S-adenosylmethionine sensor for the mTORC1 pathway." ]

[ 2013, 2017 ]

2

[]

0

null

[ "Eukaryota", "candidate division WOR-3 bacterium" ]

[ 3307, 1 ]

2

[ "Danio rerio", "Drosophila melanogaster", "Homo sapiens", "Mus musculus", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Rattus norvegicus", "Saccharomyces cerevisiae (strain ATCC 204508 / S288c)", "Schizosaccharomyces pombe (strain 972 / ATCC 24843)" ]

[ 3, 1, 3, 2, 1, 6, 1, 1 ]

8

true

Family

S-adenosylmethionine-dependent methyltransferase Bmt2-like

Bmt2/SAMTOR

9

IPR021868

21,868

Alpha-2-macroglobulin MG3 domain

Alpha_2_Macroglob_MG3

Domain

8,525

false

This is the N-terminal MG3 domain from alpha-2-macroglobulin [ ].

[]

0

[ "PFAM" ]

[ "PF11974" ]

[ "bMG3" ]

[ 8525 ]

1

[]

0

[ "4rtd", "4u48", "4u4j", "4u59", "4ziq", "4zjg", "4zjh", "5a42" ]

8

[ "PUB00039169" ]

[ "16177781" ]

[ "Structures of complement component C3 provide insights into the function and evolution of immunity." ]

[ 2005 ]

1

[]

0

null

[ "Bacteria", "Eukaryota", "metagenomes" ]

[ 8455, 10, 60 ]

3

[ "Escherichia coli (strain K12)" ]

[ 1 ]

1

true

Domain

Alpha-2-macroglobulin MG3 domain

Alpha_2_Macroglob_MG3

6

IPR021869

21,869

Ribonuclease Zc3h12a-like, NYN domain

RNase_Zc3h12_NYN

Domain

8,584

false

This domain is found in the Zc3h12a protein and NEDD4-binding protein 1 (N4BP1). Zc3h12a has been shown to be a ribonuclease that controls the stability of a set of inflammatory genes [ ]. This domain belongs to the PIN domain superfamily [ ] and it has also been identified as part of the NYN domain family [ ]. N4BP1 i...

[]

0

[ "PFAM" ]

[ "PF11977" ]

[ "RNase_Zc3h12a" ]

[ 8584 ]

1

[ "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME" ]

[ "R-DRE-9758274", "R-HSA-9758274", "R-HSA-9764302", "R-MMU-9758274", "R-XTR-9758274" ]

[ "REACTOME:R-DRE-9758274", "REACTOME:R-HSA-9758274", "REACTOME:R-HSA-9764302", "REACTOME:R-MMU-9758274", "REACTOME:R-XTR-9758274" ]

5

[ "3v32", "3v33", "3v34", "5h9v", "5h9w", "6sjd", "7ndh", "7ndi", "7ndj", "7ndk", "8wzc" ]

11

[ "PUB00053552", "PUB00056584", "PUB00101187", "PUB00159024" ]

[ "19322177", "17114934", "31133753", "32971525" ]

[ "Zc3h12a is an RNase essential for controlling immune responses by regulating mRNA decay.", "The NYN domains: novel predicted RNAses with a PIN domain-like fold.", "N4BP1 restricts HIV-1 and its inactivation by MALT1 promotes viral reactivation.", "Integration of innate immune signalling by caspase-8 cleavage...

[ 2009, 2006, 2019, 2020 ]

4

[]

0

null

[ "Archaea", "Bacteria", "Eukaryota", "unclassified sequences" ]

[ 72, 323, 8119, 70 ]

4

[ "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Homo sapiens", "Mus musculus", "Rattus norvegicus" ]

[ 6, 10, 2, 17, 14, 21 ]

6

true

Domain

Ribonuclease Zc3h12a-like, NYN domain

RNase_Zc3h12_NYN

2

IPR021870

21,870

Major vault protein, shoulder domain

MVP_shoulder

Domain

1,787

false

The major vault protein is the major polypeptide component of a large cellular ribonuclear protein complex found in the cytoplasm of eukaryotic cells. Several roles for vaults have been proposed. Vault proteins have been associated with development of multi-drug resistance [ ]. They have also being implicated in the re...

[]

0

[ "PFAM", "CDD" ]

[ "PF11978", "cd08825" ]

[ "MVP_shoulder", "MVP_shoulder" ]

[ 1787, 1628 ]

2

[ "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME" ]

[ "R-DDI-6798695", "R-DRE-6798695", "R-HSA-6798695", "R-MMU-6798695", "R-RNO-6798695" ]

[ "REACTOME:R-DDI-6798695", "REACTOME:R-DRE-6798695", "REACTOME:R-HSA-6798695", "REACTOME:R-MMU-6798695", "REACTOME:R-RNO-6798695" ]

5

[ "2qzv", "4hl8", "4v60", "6bp7", "6bp8", "7pkr", "7pky", "7pkz", "9bw5", "9bw6", "9bw7", "9mxh", "9mxj", "9mxv", "9r86", "9r87" ]

16

[ "PUB00050447", "PUB00080565", "PUB00080571" ]

[ "19150846", "23083532", "18759128" ]

[ "The structure of rat liver vault at 3.5 angstrom resolution.", "The role of major vault protein (MVP) in drug resistance.", "Vaults and the major vault protein: novel roles in signal pathway regulation and immunity." ]

[ 2009, 2012, 2009 ]

3

[]

0

null

[ "Bacteria", "Candidatus Lokiarchaeum ossiferum", "Eukaryota", "metagenomes" ]

[ 66, 1, 1711, 9 ]

4

[ "Danio rerio", "Homo sapiens", "Mus musculus", "Rattus norvegicus" ]

[ 2, 8, 4, 3 ]

4

true

Domain

Major vault protein, shoulder domain

MVP_shoulder

8

IPR021871

21,871

Protein of unknown function DUF3482

DUF3482

Family

2,029

false

This presumed domain is functionally uncharacterised. This domain is found in bacteria and eukaryotes. This domain is typically between 289 to 301 amino acids in length. This domain is found associated with .

[]

0

[ "PFAM" ]

[ "PF11981" ]

[ "DUF3482" ]

[ 2029 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Eukaryota", "metagenomes" ]

[ 1995, 6, 28 ]

3

[]

0

true

Family

Protein of unknown function DUF3482

DUF3482

3

IPR021872

21,872

Csal_0991-like, N-terminal domain

Csal_0991-like_N

Domain

1,557

false

This entry represents a domain found at the N-terminal end of the probable membrane-anchored ferredoxin csal_0991 from Chromohalobacter salexigensis and similar sequences from proteobacteria. Csal_0991 participates in the electron transfer process during N,N-dimethylglycine (DMG) degradation to sarcosine [ ]. This doma...

[]

0

[ "PFAM" ]

[ "PF11982" ]

[ "DUF3483" ]

[ 1557 ]

1

[]

0

[]

0

[ "PUB00152826" ]

[ "32631860" ]

[ "Role of N,N-Dimethylglycine and Its Catabolism to Sarcosine in Chromohalobacter salexigens DSM 3043." ]

[ 2020 ]

1

[]

0

null

[ "Bacteria", "marine sediment metagenome" ]

[ 1556, 1 ]

2

[]

0

true

Domain

Csal_0991-like, N-terminal domain

Csal_0991-like_N

5

IPR021873

21,873

Cell division protein FtsA, C-terminal

FtsA_C

Domain

864

false

FtsA is essential for bacterial cell division, and co-localizes to the septal ring with FtsZ. It has been suggested that the interaction of FtsA-FtsZ has arisen through coevolution in different bacterial strains [ ]. This C-terminal domain is found in FtsA from Firmicutes (Gram-positive bacteria). It acts as an intra-m...

[]

0

[ "PFAM" ]

[ "PF11983" ]

[ "FtsA_C" ]

[ 864 ]

1

[]

0

[]

0

[ "PUB00009447", "PUB00078723" ]

[ "9352931", "25425238" ]

[ "Interactions between heterologous FtsA and FtsZ proteins at the FtsZ ring.", "Role of the FtsA C terminus as a switch for polymerization and membrane association." ]

[ 1997, 2014 ]

2

[]

0

null

[ "Bacteria" ]

[ 864 ]

1

[]

0

true

Domain

Cell division protein FtsA, C-terminal

FtsA_C

6

IPR021874

21,874

Bacteriophage Mu, Gp27

Phage_Mu_Gp27

Family

1,653

false

This entry is represented by Bacteriophage Mu, Gp27. It is probably the small subunit of terminase, which recognises viral DNA, binds to the packaging initiation site (pac) and regulates the ATPase activity of the terminase large subunit [ ]. The characteristics of the protein distribution suggest prophage matches in a...

[]

0

[ "PFAM" ]

[ "PF11985" ]

[ "Phage_Mu_Gp27" ]

[ 1653 ]

1

[]

0

[]

0

[ "PUB00097490" ]

[ "14745593" ]

[ "Characterization of Plys-proximal morphogenetic genes of transposable bacteriophage Mu." ]

[ 2004 ]

1

[]

0

null

[ "Bacteria", "Eukaryota", "Viruses", "metagenomes" ]

[ 1585, 6, 45, 17 ]

4

[]

0

true

Family

Bacteriophage Mu, Gp27

Phage_Mu_Gp27

8

IPR021875

21,875

Retrograde transport protein Dsl1 N-terminal domain

Dsl1_N_dom

Domain

67

false

Dsl1 is a peripheral membrane protein, part of the DSL1 complex, required for transport between the Golgi and the endoplasmic reticulum [ ]. It is localised to the ER membrane, and bridges the other two subunits of the complex, Tip20 and Sec39. DSL1 complex, together with conserved oligomeric Golgi (COG), Golgi-associa...

[]

0

[ "PFAM" ]

[ "PF11988" ]

[ "Dsl1_N" ]

[ 67 ]

1

[ "REACTOME" ]

[ "R-SCE-6811434" ]

[ "REACTOME:R-SCE-6811434" ]

1

[ "3etu", "3etv", "8eki" ]

3

[ "PUB00020882", "PUB00051798", "PUB00100039", "PUB00100047", "PUB00100062" ]

[ "11493604", "19151722", "32409579", "34061181", "20226673" ]

[ "The coatomer-interacting protein Dsl1p is required for Golgi-to-endoplasmic reticulum retrieval in yeast.", "Structural characterization of Tip20p and Dsl1p, subunits of the Dsl1p vesicle tethering complex.", "Structural basis for the binding of SNAREs to the multisubunit tethering complex Dsl1.", "Homology ...

[ 2001, 2009, 2020, 2021, 2010 ]

5

[]

0

null

[ "Saccharomycetes" ]

[ 67 ]

1

[ "Saccharomyces cerevisiae (strain ATCC 204508 / S288c)" ]

[ 1 ]

1

true

Domain

Retrograde transport protein Dsl1 N-terminal domain

Dsl1_N_dom

5

IPR021876

21,876

Retrograde transport protein Dsl1, C-terminal domain

Dsl1_C

Domain

150

false

Dsl1 is a peripheral membrane protein part of the DSL1 complex, required for transport between the Golgi and the endoplasmic reticulum [ , ]. It is localised to the ER membrane, and bridges the other two subunits of the complex, Tip20 and Sec39. DSL1 complex, together with conserved oligomeric Golgi (COG), Golgi-associ...

[]

0

[ "PFAM" ]

[ "PF11989" ]

[ "Dsl1_C" ]

[ 150 ]

1

[ "REACTOME" ]

[ "R-SCE-6811434" ]

[ "REACTOME:R-SCE-6811434" ]

1

[ "3k8p", "8eki", "8ftu" ]

3

[ "PUB00020882", "PUB00051798", "PUB00100039", "PUB00100047", "PUB00100062" ]

[ "11493604", "19151722", "32409579", "34061181", "20226673" ]

[ "The coatomer-interacting protein Dsl1p is required for Golgi-to-endoplasmic reticulum retrieval in yeast.", "Structural characterization of Tip20p and Dsl1p, subunits of the Dsl1p vesicle tethering complex.", "Structural basis for the binding of SNAREs to the multisubunit tethering complex Dsl1.", "Homology ...

[ 2001, 2009, 2020, 2021, 2010 ]

5

[]

0

null

[ "Fungi" ]

[ 150 ]

1

[ "Saccharomyces cerevisiae (strain ATCC 204508 / S288c)" ]

[ 1 ]

1

true

Domain

Retrograde transport protein Dsl1, C-terminal domain

Dsl1_C

4

IPR021877

21,877

Protein of unknown function DUF3487

DUF3487

Family

1,745

false

This family of proteins is functionally uncharacterised. This protein is found in bacteria. Proteins in this family are typically between 121 to 136 amino acids in length. This protein has a conserved RLN sequence motif.

[]

0

[ "PFAM", "NCBIFAM" ]

[ "PF11990", "TIGR03750" ]

[ "DUF3487", "conj_TIGR03750" ]

[ 1744, 1665 ]

2

[ "GP" ]

[ "GenProp0855" ]

[ "GP:GenProp0855" ]

1

[]

0

[]

0

[]

0

null

[ "Bacteria", "Eukaryota", "metagenomes" ]

[ 1731, 2, 12 ]

3

[]

0

true

Family

Protein of unknown function DUF3487

DUF3487

2

IPR021878

21,878

Protein-glutamine gamma-glutamyltransferase TgpA, N-terminal

TgpA_N

Domain

10,138

false

This domain can be found at the N terminus of TgpA from Pseudomonas aeruginosa. TgpA is a transglutaminase that plays a critical role in the viability of Pseudomonas aeruginosa [ , ]. This domain is composed of 5 transmembrane helices [ ].

[]

0

[ "PFAM" ]

[ "PF11992" ]

[ "TgpA_N" ]

[ 10138 ]

1

[]

0

[ "6g49", "6g4h" ]

2

[ "PUB00092521", "PUB00092522" ]

[ "23209712", "30599211" ]

[ "TgpA, a protein with a eukaryotic-like transglutaminase domain, plays a critical role in the viability of Pseudomonas aeruginosa.", "Structural and functional characterization of TgpA, a critical protein for the viability of Pseudomonas aeruginosa." ]

[ 2012, 2018 ]

2

[]

0

null

[ "Bacteria", "Eukaryota", "Halobacteriales", "unclassified sequences" ]

[ 9812, 11, 229, 86 ]

4

[]

0

true

Domain

Protein-glutamine gamma-glutamyltransferase TgpA, N-terminal

TgpA_N

2

IPR021879

21,879

VC2046 family

VC2046_fam

Family

773

false

This entry represents a group of family of uncharacterised proteins mainly found in gammaproteobacteria, including VC2046 from Vibrio cholerae (also known as QueD-like protein, ). They were annotated as ribosomal SSU S4 p proteins but there is not evidence supporting this, and it is, apparently, a missannotation. Prote...

[]

0

[ "PFAM" ]

[ "PF11993" ]

[ "VC2046" ]

[ 773 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "marine sediment metagenome" ]

[ 771, 2 ]

2

[]

0

true

Family

VC2046 family

VC2046_fam

8

IPR021880

21,880

Protein of unknown function DUF3489

DUF3489

Family

1,450

false

This family of proteins is functionally uncharacterised. This protein is found in bacteria. Proteins in this family are typically between 84 to 211 amino acids in length. This protein has a single completely conserved residue W that may be functionally important.

[]

0

[ "PFAM" ]

[ "PF11994" ]

[ "DUF3489" ]

[ 1450 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Viruses", "metagenomes" ]

[ 1428, 18, 4 ]

3

[]

0

true

Family

Protein of unknown function DUF3489

DUF3489

8

IPR021881

21,881

NPK1-activating kinesin-like protein, C-terminal

NACK_C

Domain

4,032

false

This domain is found at the C terminus of plant kinesin-like proteins NACK1 and NACK2. NACK1 (NPK1-activating kinesin-like protein 1) is key regulator of plant cytokinesis [ ]. NACK2 (TETRASPORE) is required for male meiotic cytokinesis [ ].

[]

0

[ "PFAM" ]

[ "PF11995" ]

[ "DUF3490" ]

[ 4032 ]

1

[]

0

[]

0

[ "PUB00076356", "PUB00076357" ]

[ "22006334", "12694597" ]

[ "Phosphorylation of a mitotic kinesin-like protein and a MAPKKK by cyclin-dependent kinases (CDKs) is involved in the transition to cytokinesis in plants.", "TETRASPORE encodes a kinesin required for male meiotic cytokinesis in Arabidopsis." ]

[ 2011, 2003 ]

2

[]

0

null

[ "Eukaryota" ]

[ 4032 ]

1

[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 38, 7, 88 ]

3

true

Domain

NPK1-activating kinesin-like protein, C-terminal

NACK_C

8

IPR021882

21,882

Protein of unknown function DUF3491

DUF3491

Family

190

false

This family of proteins is functionally uncharacterised. This protein is found in bacteria. Proteins in this family are typically between 286 to 3225 amino acids in length. This protein is found associated with . This protein is found associated with .

[]

0

[ "PFAM" ]

[ "PF11996" ]

[ "DUF3491" ]

[ 190 ]

1

[]

0

[ "9euv", "9euw", "9qb8", "9qbb", "9qhh" ]

5

[]

0

[]

0

null

[ "Pseudomonadati" ]

[ 190 ]

1

[]

0

true

Family

Protein of unknown function DUF3491

DUF3491

6

IPR021883

21,883

Protein LOW PSII ACCUMULATION 1-like

LPA1-like

Family

1,828

false

This entry includes Protein LOW PSII ACCUMULATION 1 (LPA1) from plants and some uncharacterised proteins from Cyanobacteria (blue-green algae). Arabidopsis LPA1 is a chaperone required for efficient photosystem II (PSII) assembly. It binds to psbA during de novo biogenesis of PSII [ ].

[]

0

[ "PFAM" ]

[ "PF11998" ]

[ "DUF3493" ]

[ 1828 ]

1

[]

0

[]

0

[ "PUB00086019" ]

[ "16531500" ]

[ "LOW PSII ACCUMULATION1 is involved in efficient assembly of photosystem II in Arabidopsis thaliana." ]

[ 2006 ]

1

[]

0

null

[ "Cyanobacteriota", "Eukaryota", "marine metagenome" ]

[ 349, 1478, 1 ]

3

[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 11, 5, 13 ]

3

true

Family

Protein LOW PSII ACCUMULATION 1-like

LPA1-like

3

IPR021884

21,884

Ice-binding protein

Ice-bd_prot

Family

2,774

false

This entry represents ice-binding proteins mainly found in bacteria and fungi. In Antarctic bacterium Flavobacterium frigoris PS1, FfIBP is an ice-binding protein (IBP) that inhibits ice growth through direct interaction with ice crystals to permit the survival of polar organisms in extremely cold environments [ ]. In ...

[]

0

[ "PFAM" ]

[ "PF11999" ]

[ "Ice_binding" ]

[ 2774 ]

1

[]

0

[ "3uyu", "3uyv", "3vn3", "3wp9", "4nu2", "4nu3", "4nuh", "5b5h", "5uyt", "6a8k", "6bg8", "6eio", "7bwx", "7bwy", "7dc5", "7ddb", "7ehk", "8x0z", "8x1l", "8x1o", "8x1p", "9lhn", "9lhr", "9lhs", "9li0" ]

25

[ "PUB00058444", "PUB00089804", "PUB00094907", "PUB00094908" ]

[ "22303017", "24699650", "30680879", "29498209" ]

[ "Structural basis for the antifreeze activity of an ice-binding protein from an Arctic yeast.", "Structure-based characterization and antifreeze properties of a hyperactive ice-binding protein from the Antarctic bacterium Flavobacterium frigoris PS1.", "Ice-binding proteins and the 'domain of unknown function' ...

[ 2012, 2014, 2019, 2018 ]

4

[]

0

null

[ "Archaea", "Bacteria", "Eukaryota", "metagenomes", "unclassified Klosneuvirinae" ]

[ 18, 1734, 972, 45, 5 ]

5

[]

0

true

Family

Ice-binding protein

Ice-bd_prot

6

IPR021885

21,885

Domain of unknown function DUF3496

DUF3496

Domain

1,984

false

This presumed domain is functionally uncharacterised. This domain is found in eukaryotes. This domain is about 110 amino acids in length.

[]

0

[ "PFAM" ]

[ "PF12001" ]

[ "DUF3496" ]

[ 1984 ]

1

[ "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME" ]

[ "R-HSA-9696264", "R-HSA-9696270", "R-HSA-9696273", "R-MMU-9696264", "R-MMU-9696270", "R-MMU-9696273" ]

[ "REACTOME:R-HSA-9696264", "REACTOME:R-HSA-9696270", "REACTOME:R-HSA-9696273", "REACTOME:R-MMU-9696264", "REACTOME:R-MMU-9696270", "REACTOME:R-MMU-9696273" ]

6

[]

0

[]

0

[]

0

null

[ "Bacteria", "Eukaryota" ]

[ 3, 1981 ]

2

[ "Danio rerio", "Homo sapiens", "Mus musculus", "Rattus norvegicus" ]

[ 36, 28, 14, 11 ]

4

true

Domain

Domain of unknown function DUF3496

DUF3496

4

IPR021886

21,886

MgsA AAA+ ATPase, C-terminal

MgsA_C

Domain

30,552

false

The MgsA protein possesses DNA-dependent ATPase and ssDNA annealing activities [ ]. MgsA contributes to the recovery of stalled replication forks and therefore prevents genomic instability caused by aberrant DNA replication [ ]. Additionally, MgsA may play a role in chromosomal segregation [ ]. This is consistent with ...

[]

0

[ "PFAM" ]

[ "PF12002" ]

[ "MgsA_C" ]

[ 30552 ]

1

[]

0

[ "2qw6", "2r9g", "3bge", "3ctd", "3pvs", "8g28" ]

6

[ "PUB00053553", "PUB00071246", "PUB00160319" ]

[ "15743409", "21297161", "15670210" ]

[ "Functional overlap between RecA and MgsA (RarA) in the rescue of stalled replication forks in Escherichia coli.", "Structure and biochemical activities of Escherichia coli MgsA.", "Human Werner helicase interacting protein 1 (WRNIP1) functions as a novel modulator for DNA polymerase delta." ]

[ 2005, 2011, 2005 ]

3

[]

0

null

[ "Archaea", "Bacteria", "Caudoviricetes", "Eukaryota", "unclassified sequences" ]

[ 5, 26264, 6, 3786, 491 ]

5

[ "Arabidopsis thaliana", "Danio rerio", "Escherichia coli (strain K12)", "Homo sapiens", "Mus musculus", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Rattus norvegicus", "Saccharomyces cerevisiae (strain ATCC 204508 / S288c)", "Schizosaccharomyces pombe (s...

[ 5, 1, 1, 2, 1, 1, 4, 1, 1 ]

9

true

Domain

MgsA AAA+ ATPase, C-terminal

MgsA_C

4

IPR021887

21,887

Disabled homolog 2-interacting protein, C-terminal domain

DAB2P_C

Domain

8,210

false

This entry represents a domain found at the C terminus of some GTPase-activating proteins (also known as GAP) found in animals, including Disabled homologue 2-interacting protein (DAB2P) and Ras/Rap GTPase-activating protein SynGAP (SYGP1). DAB2P functions as a tumour suppressor that is also involved in several process...

[]

0

[ "PFAM" ]

[ "PF12004" ]

[ "DAB2P_C" ]

[ 8210 ]

1

[ "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME" ]

[ "R-DME-5658442", "R-HSA-5658442", "R-HSA-9696264", "R-HSA-9696273", "R-MMU-5658442", "R-RNO-5658442" ]

[ "REACTOME:R-DME-5658442", "REACTOME:R-HSA-5658442", "REACTOME:R-HSA-9696264", "REACTOME:R-HSA-9696273", "REACTOME:R-MMU-5658442", "REACTOME:R-RNO-5658442" ]

6

[ "5jxc" ]

1

[ "PUB00072683", "PUB00072690", "PUB00100693", "PUB00100694", "PUB00100695", "PUB00100696" ]

[ "23326475", "19033661", "27565345", "16537406", "19948740", "15500970" ]

[ "Dab2IP GTPase activating protein regulates dendrite development and synapse number in cerebellum.", "AIP1 functions as an endogenous inhibitor of VEGFR2-mediated signaling and inflammatory angiogenesis in mice.", "Phase Transition in Postsynaptic Densities Underlies Formation of Synaptic Complexes and Synaptic...

[ 2013, 2008, 2016, 2006, 2010, 2004 ]

6

[]

0

null

[ "Eumetazoa" ]

[ 8210 ]

1

[ "Danio rerio", "Drosophila melanogaster", "Homo sapiens", "Mus musculus", "Rattus norvegicus" ]

[ 94, 9, 16, 25, 36 ]

5

true

Domain

Disabled homolog 2-interacting protein, C-terminal domain

DAB2P_C

3

IPR021888

21,888

Protein of unknown function DUF3499

DUF3499

Family

4,322

false

This family of proteins is functionally uncharacterised. This protein is found in bacteria. Proteins in this family are typically between 125 to 163 amino acids in length.

[]

0

[ "PFAM" ]

[ "PF12005" ]

[ "DUF3499" ]

[ 4322 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "metagenomes" ]

[ 4165, 157 ]

2

[]

0

true

Family

Protein of unknown function DUF3499

DUF3499

2

IPR021889

21,889

Protein of unknown function DUF3500

DUF3500

Family

3,987

false

This family of proteins is functionally uncharacterised. This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 335 to 438 amino acids in length. This protein has a conserved GHH sequence motif. This protein has two completely conserved G residues that may be functionally import...

[]

0

[ "PFAM", "PANTHER" ]

[ "PF12006", "PTHR37489" ]

[ "DUF3500", "" ]

[ 3984, 3783 ]

2

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Eukaryota", "ecological metagenomes" ]

[ 2589, 1329, 69 ]

3

[ "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)" ]

[ 1 ]

1

true

Family

Protein of unknown function DUF3500

DUF3500

6

IPR021890

21,890

Protein of unknown function DUF3501

DUF3501

Family

1,007

false

This family of proteins is functionally uncharacterised. This protein is found in bacteria and archaea. Proteins in this family are about 200 amino acids in length. The structure of protein of unknown function (YP_111841.1) from B. pseudomallei has been solved.

[]

0

[ "PFAM" ]

[ "PF12007" ]

[ "DUF3501" ]

[ 1007 ]

1

[]

0

[ "3fjv" ]

1

[]

0

[]

0

null

[ "Archaea", "Bacteria", "Eukaryota", "unclassified sequences" ]

[ 56, 831, 10, 110 ]

4

[]

0

true

Family

Protein of unknown function DUF3501

DUF3501

2

IPR021891

21,891

Telomerase ribonucleoprotein complex - RNA-binding domain

Telomerase_RBD

Domain

3,882

false

Telomeres in most organisms are comprised of tandem simple sequence repeats [ ]. The total length of telomeric repeat sequence at each chromosome end is determined in a balance of sequence loss and sequence addition [ ]. One major influence on telomere length is the enzyme telomerase [ ]. It is a reverse transcriptase ...

[ "GO:0003964" ]

[ "RNA-directed DNA polymerase activity" ]

[ "molecular_function" ]

1

[ "PFAM", "SMART" ]

[ "PF12009", "SM00975" ]

[ "Telomerase_RBD", "Telomerase_RBD" ]

[ 3869, 3615 ]

2

[ "EC", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME" ]

[ "2.7.7.49", "R-HSA-171319", "R-HSA-201722", "R-HSA-9825895", "R-MMU-171319", "R-MMU-201722", "R-RNO-171319", "R-RNO-201722" ]

[ "EC:2.7.7.49", "REACTOME:R-HSA-171319", "REACTOME:R-HSA-201722", "REACTOME:R-HSA-9825895", "REACTOME:R-MMU-171319", "REACTOME:R-MMU-201722", "REACTOME:R-RNO-171319", "REACTOME:R-RNO-201722" ]

8

[ "2r4g", "3du5", "3du6", "3kyl", "4lmo", "4o26", "5c9h", "5cqg", "6d6v", "6e53", "6uso", "6usp", "6usq", "6usr", "6zd1", "6zd2", "6zd6", "6zdp", "6zdq", "6zdu", "7bg9", "7kqm", "7kqn", "7lma", "7lmb", "7qxa", "7qxb", "7qxs", "7sbe", "7trd", "7tre", "7trf"...

39

[ "PUB00049245", "PUB00053554" ]

[ "17997966", "9671704" ]

[ "Structure of the RNA-binding domain of telomerase: implications for RNA recognition and binding.", "The reverse transcriptase component of the Tetrahymena telomerase ribonucleoprotein complex." ]

[ 2007, 1998 ]

2

[]

0

null

[ "Eukaryota" ]

[ 3882 ]

1

[ "Arabidopsis thaliana", "Danio rerio", "Homo sapiens", "Mus musculus", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Oryza sativa subsp. japonica", "Rattus norvegicus", "Saccharomyces cerevisiae (strain ATCC 204508 / S288c)", "Schizosaccharomyces pombe (st...

[ 5, 1, 6, 4, 1, 1, 3, 1, 1, 10 ]

10

true

Domain

Telomerase ribonucleoprotein complex - RNA-binding domain

Telomerase_RBD

4

IPR021892

21,892

RNA helicase NPH-II

NPH-II

Family

192

false

RNA helicase NPH-II or I8 is found in Poxviridae. It is essential for viral replication. Plays an important role during transcription of early mRNAs, presumably by preventing R-loop formation behind the elongating RNA polymerase. Acts as NTP-dependent helicase that catalyzes unidirectional unwinding of 3'tailed duplex ...

[ "GO:0017111" ]

[ "ribonucleoside triphosphate phosphatase activity" ]

[ "molecular_function" ]

1

[ "PFAM" ]

[ "PF12011" ]

[ "NPH-II" ]

[ 192 ]

1

[ "EC" ]

[ "3.6.4.13" ]

[ "EC:3.6.4.13" ]

1

[]

0

[ "PUB00053892" ]

[ "8970979" ]

[ "Vaccinia virions lacking the RNA helicase nucleoside triphosphate phosphohydrolase II are defective in early transcription." ]

[ 1996 ]

1

[]

0

null

[ "Poxviridae" ]

[ 192 ]

1

[]

0

true

Family

RNA helicase NPH-II

NPH-II

7

IPR021896

21,896

THAP9-like, helix-turn-helix domain

THAP9-like_HTH

Domain

3,095

false

This entry represents the DNA-binding helix-turn-helix domain (HTH) of human DNA transposase THAP9, which specifically recognises the bipartite 5'-TXXGGGX(A/T)-3' consensus motif and mediates transposition [ , , ].

[]

0

[ "PFAM" ]

[ "PF12017" ]

[ "Tnp_P_element" ]

[ 3095 ]

1

[]

0

[]

0

[ "PUB00062395", "PUB00078696", "PUB00102717", "PUB00151940" ]

[ "2416475", "23349291", "31659330", "20010837" ]

[ "Identification and immunochemical analysis of biologically active Drosophila P element transposase.", "The human THAP9 gene encodes an active P-element DNA transposase.", "Structure of a P element transposase-DNA complex reveals unusual DNA structures and GTP-DNA contacts.", "THAP proteins target specific DN...

[ 1986, 2013, 2019, 2010 ]

4

[]

0

null

[ "Eukaryota" ]

[ 3095 ]

1

[ "Danio rerio", "Drosophila melanogaster", "Homo sapiens" ]

[ 1, 1, 2 ]

3

true

Domain

THAP9-like, helix-turn-helix domain

THAP9-like_HTH

6

IPR021897

21,897

Cilia- and flagella-associated protein 206

FAP206

Family

2,277

false

Proteins in this entry are found in eukaryotes. There are two conserved sequence motifs: GFC and GLL. This family is also known as UPF0704, whose members include FAP206, a protein associated with cilia and flagella. In the ciliate Tetrahymena, the cilium has radial spokes, each of which is a macromolecular complex esse...

[]

0

[ "PFAM", "PANTHER" ]

[ "PF12018", "PTHR21442" ]

[ "FAP206", "" ]

[ 1863, 2238 ]

2

[]

0

[ "9e5c" ]

1

[ "PUB00082324" ]

[ "25540426" ]

[ "FAP206 is a microtubule-docking adapter for ciliary radial spoke 2 and dynein c." ]

[ 2015 ]

1

[]

0

null

[ "Eukaryota", "Planctomycetia" ]

[ 2269, 8 ]

2

[ "Danio rerio", "Drosophila melanogaster", "Homo sapiens", "Mus musculus", "Rattus norvegicus" ]

[ 7, 2, 6, 2, 6 ]

5

true

Family

Cilia- and flagella-associated protein 206

FAP206

4

IPR021898

21,898

Protein of unknown function DUF3509

DUF3509

Family

2,073

false

This family of proteins is functionally uncharacterised. This protein is found in bacteria. Proteins in this family are typically between 92 to 110 amino acids in length. This protein has two completely conserved residues (G and R) that may be functionally important.

[]

0

[ "PFAM" ]

[ "PF12021" ]

[ "DUF3509" ]

[ 2073 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Diploscapter pachys", "Pseudomonadaceae", "marine sediment metagenome" ]

[ 2, 2070, 1 ]

3

[]

0

true

Family

Protein of unknown function DUF3509

DUF3509

1

IPR021899

21,899

Protein of unknown function DUF3511

DUF3511

Family

3,684

false

This presumed domain is functionally uncharacterised. This domain is found in eukaryotes. This domain is about 50 amino acids in length. This domain has two completely conserved residues (Y and K) that may be functionally important.

[]

0

[ "PFAM" ]

[ "PF12023" ]

[ "DUF3511" ]

[ 3684 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Embryophyta" ]

[ 3684 ]

1

[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 27, 21, 36 ]

3

true

Family

Protein of unknown function DUF3511

DUF3511

3

IPR021900

21,900

Protein of unknown function DUF3512

DUF3512

Family

3,493

false

This presumed domain is functionally uncharacterised. This domain is found in eukaryotes. This domain is typically between 231 to 249 amino acids in length. This domain is found associated with .

[]

0

[ "PFAM" ]

[ "PF12024" ]

[ "DUF3512" ]

[ 3493 ]

1

[ "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME" ]

[ "R-HSA-6804758", "R-HSA-9933939", "R-HSA-9933947", "R-MMU-6804758", "R-MMU-9933939", "R-MMU-9933947", "R-XTR-9933947" ]

[ "REACTOME:R-HSA-6804758", "REACTOME:R-HSA-9933939", "REACTOME:R-HSA-9933947", "REACTOME:R-MMU-6804758", "REACTOME:R-MMU-9933939", "REACTOME:R-MMU-9933947", "REACTOME:R-XTR-9933947" ]

7

[ "7vdv", "7y8r" ]

2

[]

0

[]

0

null

[ "Opisthokonta" ]

[ 3493 ]

1

[ "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Homo sapiens", "Mus musculus", "Rattus norvegicus" ]

[ 2, 16, 1, 9, 5, 5 ]

6

true

Family

Protein of unknown function DUF3512

DUF3512

1

IPR021901

21,901

CAS family, C-terminal

CAS_C

Domain

5,448

false

This domain is found in the C terminus of the CAS family members. The CAS (Crk-Associated Substrate) protein family is a group of scaffolding proteins that play important modulatory roles in both normal and pathological cell growth regulation. They contain an N-terminal Src homology 3 (SH3) domain and a substrate domai...

[]

0

[ "PFAM" ]

[ "PF12026" ]

[ "CAS_C" ]

[ 5448 ]

1

[ "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME" ]

[ "R-HSA-186763", "R-HSA-372708", "R-HSA-4420097", "R-HSA-8849471", "R-MMU-186763", "R-MMU-372708", "R-MMU-4420097", "R-MMU-8849471", "R-RNO-186763", "R-RNO-372708", "R-RNO-4420097", "R-RNO-8849471" ]

[ "REACTOME:R-HSA-186763", "REACTOME:R-HSA-372708", "REACTOME:R-HSA-4420097", "REACTOME:R-HSA-8849471", "REACTOME:R-MMU-186763", "REACTOME:R-MMU-372708", "REACTOME:R-MMU-4420097", "REACTOME:R-MMU-8849471", "REACTOME:R-RNO-186763", "REACTOME:R-RNO-372708", "REACTOME:R-RNO-4420097", "REACTOME:R-RN...

12

[ "3t6g", "5w93" ]

2

[ "PUB00069470" ]

[ "19937461" ]

[ "CAS proteins in normal and pathological cell growth control." ]

[ 2010 ]

1

[]

[ "IPR046976" ]

0

1

0

[ "Metazoa" ]

[ 5448 ]

1

[ "Danio rerio", "Drosophila melanogaster", "Homo sapiens", "Mus musculus", "Rattus norvegicus" ]

[ 8, 4, 13, 13, 19 ]

5

true

Domain

CAS family, C-terminal

CAS_C

7

IPR021902

21,902

Protein of unknown function DUF3514

DUF3514

Family

47

false

This family of proteins is functionally uncharacterised. This protein is found in bacteria. Proteins in this family are typically between 368 to 823 amino acids in length.

[]

0

[ "PFAM" ]

[ "PF12027" ]

[ "DUF3514" ]

[ 47 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "canis group" ]

[ 47 ]

1

[]

0

true

Family

Protein of unknown function DUF3514

DUF3514

2

IPR021903

21,903

Protein of unknown function DUF3515

DUF3515

Family

4,217

false

This family of proteins is functionally uncharacterised. This protein is found in bacteria. Proteins in this family are typically between 166 to 214 amino acids in length. This protein has a conserved RCG sequence motif.

[]

0

[ "PFAM" ]

[ "PF12028" ]

[ "DUF3515" ]

[ 4217 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "metagenomes" ]

[ 4183, 34 ]

2

[]

0

true

Family

Protein of unknown function DUF3515

DUF3515

5

IPR021904

21,904

Protein of unknown function DUF3516

DUF3516

Family

4,702

false

This presumed domain is functionally uncharacterised. This domain is found in bacteria. This domain is typically between 460 to 473 amino acids in length. This domain is found associated with , .

[]

0

[ "PFAM" ]

[ "PF12029" ]

[ "DUF3516" ]

[ 4702 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Eukaryota", "metagenomes" ]

[ 4648, 31, 23 ]

3

[]

0

true

Family

Protein of unknown function DUF3516

DUF3516

8

IPR021905

21,905

Ubiquitin C-terminal hydrolase-like, DUF3517

DUF3517

Domain

5,677

false

This domain is found at the C-terminal end of ubiquitin C-terminal hydrolases and similar sequences from eukaryotes. It is functionally uncharacterised, but it is found associated with . Deubiquitinating enzymes (DUBs) are capable of removing ubiquitin (Ub) from protein substrates and are involved in numerous biologica...

[]

0

[ "PFAM" ]

[ "PF12030" ]

[ "DUF3517" ]

[ 5677 ]

1

[ "EC", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME" ]

[ "3.4.19.12", "R-DME-2173795", "R-DME-5689880", "R-DME-8866652", "R-DME-9013420", "R-DME-9013424", "R-DME-9033241", "R-HSA-201681", "R-HSA-2173795", "R-HSA-5689880", "R-HSA-8866652", "R-HSA-9013420", "R-HSA-9013424", "R-HSA-9033241", "R-HSA-977225", "R-MMU-201681", "R-MMU-2173795", ...

[ "EC:3.4.19.12", "REACTOME:R-DME-2173795", "REACTOME:R-DME-5689880", "REACTOME:R-DME-8866652", "REACTOME:R-DME-9013420", "REACTOME:R-DME-9013424", "REACTOME:R-DME-9033241", "REACTOME:R-HSA-201681", "REACTOME:R-HSA-2173795", "REACTOME:R-HSA-5689880", "REACTOME:R-HSA-8866652", "REACTOME:R-HSA-901...

22

[ "7yxx", "7yxy" ]

2

[ "PUB00081364", "PUB00083511", "PUB00094365", "PUB00094366", "PUB00094382", "PUB00094383" ]

[ "20302916", "15571815", "31845741", "30498503", "4942677", "3005225" ]

[ "The potential role of ubiquitin c-terminal hydrolases in oncogenesis.", "Mechanism and function of deubiquitinating enzymes.", "Bacterial DUBs: deubiquitination beyond the seven classes.", "Characterization of the Ubiquitin C-Terminal Hydrolase and Ubiquitin-Specific Protease Families in Rice (Oryza sativa)....

[ 2010, 2004, 2019, 2018, 1971, 1986 ]

6

[]

0

null

[ "Eukaryota" ]

[ 5677 ]

1

[ "Danio rerio", "Drosophila melanogaster", "Homo sapiens", "Mus musculus", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Rattus norvegicus" ]

[ 6, 10, 13, 11, 2, 15 ]

6

true

Domain

Ubiquitin C-terminal hydrolase-like, DUF3517

DUF3517

5

IPR021906

21,906

SWI/SNF-like complex subunit BAF250/Osa

BAF250/Osa

Family

8,147

false

This entry represents the mammalian BAF250a/b and its homologue osa from fruit flies [ ]. They are part of the SWI/SNF-like ATP-dependent chromatin remodelling complex that regulates gene expression through regulating nucleosome remodelling. In humans there are two BAF250 isoforms, BAF250a/ARID1a and BAF250b/ARID1b. BA...

[ "GO:0006338", "GO:0016514", "GO:0035060" ]

[ "chromatin remodeling", "SWI/SNF complex", "brahma complex" ]

[ "biological_process", "cellular_component", "cellular_component" ]

3

[ "PANTHER" ]

[ "PTHR12656" ]

[ "" ]

[ 8147 ]

1

[ "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME" ]

[ "R-DME-3214858", "R-DME-8939243", "R-DME-9933937", "R-DME-9933946", "R-DME-9934037", "R-HSA-3214858", "R-HSA-8939243", "R-HSA-9764790", "R-HSA-9824585", "R-HSA-9845323", "R-HSA-9933937", "R-HSA-9933946", "R-HSA-9934037", "R-MMU-3214858", "R-MMU-8939243", "R-MMU-9933937", "R-MMU-99339...

[ "REACTOME:R-DME-3214858", "REACTOME:R-DME-8939243", "REACTOME:R-DME-9933937", "REACTOME:R-DME-9933946", "REACTOME:R-DME-9934037", "REACTOME:R-HSA-3214858", "REACTOME:R-HSA-8939243", "REACTOME:R-HSA-9764790", "REACTOME:R-HSA-9824585", "REACTOME:R-HSA-9845323", "REACTOME:R-HSA-9933937", "REACTOM...

18

[ "1ryu", "2cxy", "2eh9", "6lth", "6ltj" ]

5

[ "PUB00071658", "PUB00071661", "PUB00078694", "PUB00078695" ]

[ "20086098", "11124806", "18846319", "22461668" ]

[ "Mammalian SWI/SNF--a subunit BAF250/ARID1 is an E3 ubiquitin ligase that targets histone H2B.", "Osa-containing Brahma chromatin remodeling complexes are required for the repression of wingless target genes.", "LFR, which encodes a novel nuclear-localized Armadillo-repeat protein, affects multiple developmenta...

[ 2010, 2000, 2009, 2012 ]

4

[]

0

null

[ "Eukaryota" ]

[ 8147 ]

1

[ "Arabidopsis thaliana", "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Homo sapiens", "Mus musculus", "Oryza sativa subsp. japonica", "Rattus norvegicus", "Zea mays" ]

[ 3, 3, 27, 6, 31, 12, 2, 10, 6 ]

9

true

Family

SWI/SNF-like complex subunit BAF250/Osa

BAF250/Osa

2

IPR021907

21,907

Protein of unknown function DUF3519

DUF3519

Family

284

false

This family of proteins is functionally uncharacterised. This protein is found in bacteria. Proteins in this family are typically between 117 to 1154 amino acids in length. This protein has a single completely conserved residue Q that may be functionally important.

[]

0

[ "PFAM" ]

[ "PF12033" ]

[ "DUF3519" ]

[ 284 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Helicobacter", "Helicobacter phage KHP40" ]

[ 283, 1 ]

2

[]

0

true

Family

Protein of unknown function DUF3519

DUF3519

8

IPR021910

21,910

NGX6/PGAP6/MYMK

Family

5,278

false

Proteins in this family include PGAP6 (also known as TMEM8A), NGX6 (also known as TMEM8B) and myomaker (also known as TMEM8C). TMEM8C is embedded in the plasma membrane with seven membrane-spanning regions and a required intracellular C-terminal tail. It is essential for myoblast fusion and sufficient to promote fusion...

[ "GO:0016020" ]

[ "membrane" ]

[ "cellular_component" ]

1

[ "PFAM", "PANTHER" ]

[ "PF12036", "PTHR14319" ]

[ "DUF3522", "" ]

[ 4971, 4941 ]

2

[]

0

[ "8t03", "8t04", "8t05", "8t06", "8t07" ]

5

[ "PUB00086874", "PUB00086875", "PUB00086876" ]

[ "26858401", "27881714", "15498789" ]

[ "Structure-function analysis of myomaker domains required for myoblast fusion.", "A GPI processing phospholipase A2, PGAP6, modulates Nodal signaling in embryos by shedding CRIPTO.", "Role of a novel EGF-like domain-containing gene NGX6 in cell adhesion modulation in nasopharyngeal carcinoma cells." ]

[ 2016, 2016, 2005 ]

3

[]

0

null

[ "Eukaryota", "metagenomes" ]

[ 5274, 4 ]

2

[ "Arabidopsis thaliana", "Danio rerio", "Drosophila melanogaster", "Homo sapiens", "Mus musculus", "Oryza sativa subsp. japonica", "Rattus norvegicus", "Zea mays" ]

[ 8, 6, 2, 7, 8, 4, 10, 18 ]

8

true

Family

NGX6/PGAP6/MYMK

5

IPR021911

21,911

ATPase family AAA domain-containing protein 3, N-terminal

ATAD3_N

Domain

4,218

false

This is the conserved N-terminal domain of ATPase family AAA domain-containing protein 3 (ATAD3) which is involved in dimerisation [ ] and interacts with the inner surface of the outer mitochondrial membrane [ ]. This domain is found associated with the AAA ATPase domain . ATAD3 is essential for mitochondrial network o...

[]

0

[ "PFAM" ]

[ "PF12037" ]

[ "ATAD3_N" ]

[ 4218 ]

1

[ "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME" ]

[ "R-BTA-6798695", "R-CEL-6798695", "R-DME-6798695", "R-HSA-6798695", "R-MMU-6798695", "R-RNO-6798695", "R-XTR-6798695" ]

[ "REACTOME:R-BTA-6798695", "REACTOME:R-CEL-6798695", "REACTOME:R-DME-6798695", "REACTOME:R-HSA-6798695", "REACTOME:R-MMU-6798695", "REACTOME:R-RNO-6798695", "REACTOME:R-XTR-6798695" ]

7

[]

0

[ "PUB00089261", "PUB00097486" ]

[ "20154147", "22664726" ]

[ "The AAA+ ATPase ATAD3A controls mitochondrial dynamics at the interface of the inner and outer membranes.", "ATAD3B is a human embryonic stem cell specific mitochondrial protein, re-expressed in cancer cells, that functions as dominant negative for the ubiquitous ATAD3A." ]

[ 2010, 2012 ]

2

[]

0

null

[ "Eukaryota" ]

[ 4218 ]

1

[ "Arabidopsis thaliana", "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Homo sapiens", "Mus musculus", "Oryza sativa subsp. japonica", "Rattus norvegicus", "Zea mays" ]

[ 19, 1, 1, 3, 9, 5, 7, 3, 27 ]

9

true

Domain

ATPase family AAA domain-containing protein 3, N-terminal

ATAD3_N

2

IPR021912

21,912

Protein of unknown function DUF3525

DUF3525

Family

201

false

This family of proteins is functionally uncharacterised. This protein is found in viruses. Proteins in this family are about 360 amino acids in length.

[]

0

[ "PFAM" ]

[ "PF12039" ]

[ "DUF3525" ]

[ 201 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Hypoviridae", "viral metagenome" ]

[ 200, 1 ]

2

[]

0

true

Family

Protein of unknown function DUF3525

DUF3525

6

IPR021914

21,914

Transcriptional factor DELLA, N-terminal

TF_DELLA_N

Domain

2,568

false

Gibberellins are plant hormones which have great impact on growth signalling. DELLA proteins are transcriptional regulators of growth related proteins that lack a DNA binding domain and exert its negative regulation of gibberellin responses through interaction with other transcription factors [ ]. DELLAs are downregula...

[]

0

[ "PFAM" ]

[ "PF12041" ]

[ "DELLA" ]

[ 2568 ]

1

[]

0

[ "2zsh", "2zsi", "9lum", "9lun", "9luo", "9lup", "9o4j", "9o4k", "9oi8" ]

9

[ "PUB00050430", "PUB00097402", "PUB00097403" ]

[ "19037309", "24989044", "25035403" ]

[ "Gibberellin-induced DELLA recognition by the gibberellin receptor GID1.", "Arabidopsis DELLA and two HD-ZIP transcription factors regulate GA signaling in the epidermis through the L1 box cis-element.", "DELLAs function as coactivators of GAI-ASSOCIATED FACTOR1 in regulation of gibberellin homeostasis and sign...

[ 2008, 2014, 2014 ]

3

[]

0

null

[ "Embryophyta" ]

[ 2568 ]

1

[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 21, 2, 10 ]

3

true

Domain

Transcriptional factor DELLA, N-terminal

TF_DELLA_N

5

IPR021915

21,915

Tubuliform egg casing silk strands structural domain

RP1-2

Domain

256

false

Spiders use fibroins to make silk strands. This family includes tubuliform silk fibroins which are used to protect egg cases. This domain is a structural domain which is found in repeats of up to 20 in many individuals (although this is not necessarily the case). RP1 makes up structural domains in the N-terminal while ...

[]

0

[ "PFAM" ]

[ "PF12042" ]

[ "RP1-2" ]

[ 256 ]

1

[]

0

[ "2k3n", "2k3o", "2lyi", "2mqa", "2mu3", "9lie", "9lif" ]

7

[ "PUB00048216" ]

[ "19458259" ]

[ "Solution structure of eggcase silk protein and its implications for silk fiber formation." ]

[ 2009 ]

1

[]

0

null

[ "Eukaryota" ]

[ 256 ]

1

[]

0

true

Domain

Tubuliform egg casing silk strands structural domain

RP1-2

2

IPR021916

21,916

Protein of unknown function DUF3527

DUF3527

Family

3,305

false

This presumed domain is functionally uncharacterised. This domain is found in eukaryotes. This domain is about 120 amino acids in length. This domain has a conserved CDCGGWD sequence motif.

[]

0

[ "PFAM" ]

[ "PF12043" ]

[ "DUF3527" ]

[ 3305 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Streptophyta" ]

[ 3305 ]

1

[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 40, 14, 19 ]

3

true

Family

Protein of unknown function DUF3527

DUF3527

9

IPR021917

21,917

Uncharacterised protein family, zinc metallopeptidase-like

Unchr_Zn-peptidase-like

Family

3,244

false

This family of proteins is functionally uncharacterised. However, it does contain an HEXXH motif characteristic of metallopeptidases. This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 625 to 773 amino acids in length.

[]

0

[ "PFAM" ]

[ "PF12044" ]

[ "Metallopep" ]

[ 3244 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Eukaryota", "ecological metagenomes" ]

[ 40, 3200, 4 ]

3

[ "Drosophila melanogaster", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Saccharomyces cerevisiae (strain ATCC 204508 / S288c)", "Schizosaccharomyces pombe (strain 972 / ATCC 24843)" ]

[ 1, 1, 1, 1 ]

4

true

Family

Uncharacterised protein family, zinc metallopeptidase-like

Unchr_Zn-peptidase-like

9

IPR021918

21,918

Domain of unknown function DUF3528, homeobox protein, eukaryotic

DUF3528

Domain

2,591

false

This domain of unknown function is found at the N terminus of some Homeobox proteins belonging to the ABD-B family. It is found in association with .

[]

0

[ "PFAM" ]

[ "PF12045" ]

[ "DUF3528" ]

[ 2591 ]

1

[ "REACTOME" ]

[ "R-HSA-9830674" ]

[ "REACTOME:R-HSA-9830674" ]

1

[]

0

[]

0

[]

0

null

[ "Vertebrata" ]

[ 2591 ]

1

[ "Danio rerio", "Homo sapiens", "Mus musculus", "Rattus norvegicus" ]

[ 9, 7, 4, 6 ]

4

true

Domain

Domain of unknown function DUF3528, homeobox protein, eukaryotic

DUF3528

2

IPR021919

21,919

Cofactor assembly of complex C subunit B, CCB1

CCB1

Family

1,093

false

Cofactor maturation pathways such as the CCB system (system IV) for cytochrome c-heme attachment are conserved in all organisms performing oxygenic photosynthesis [ ]. The CCB system consists of four proteins: CCB1-4. The four CCBs are well conserved between green algae and plants [ ]. This entry represents CBB1.

[]

0

[ "PFAM", "PANTHER" ]

[ "PF12046", "PTHR35302" ]

[ "CCB1", "" ]

[ 1075, 1080 ]

2

[]

0

[]

0

[ "PUB00075312", "PUB00075315" ]

[ "17535914", "18593701" ]

[ "A specific c-type cytochrome maturation system is required for oxygenic photosynthesis.", "A novel pathway of cytochrome c biogenesis is involved in the assembly of the cytochrome b6f complex in arabidopsis chloroplasts." ]

[ 2007, 2008 ]

2

[]

0

null

[ "Bacteria", "Eukaryota" ]

[ 370, 723 ]

2

[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 4, 4, 4 ]

3

true

Family

Cofactor assembly of complex C subunit B, CCB1

CCB1

7

IPR021922

21,922

Par3/HAL, N-terminal

Par3/HAL_N

Domain

6,163

false

This domain is found in eukaryotes and is about 150 amino acids in length. It has a conserved GILD sequence motif. Some proteins containing this domain are essential for cell polarity establishment and maintenance such as Par3 (partitioning defective), and some are involved in conversion of histidine into ammonia (a cr...

[]

0

[ "PFAM" ]

[ "PF12053" ]

[ "Par3_HAL_N_term" ]

[ 6163 ]

1

[ "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME" ]

[ "R-CEL-2173791", "R-CEL-70921", "R-HSA-2173791", "R-HSA-420029", "R-MMU-2173791", "R-MMU-420029", "R-MMU-70921", "R-RNO-2173791", "R-RNO-420029", "R-RNO-70921" ]

[ "REACTOME:R-CEL-2173791", "REACTOME:R-CEL-70921", "REACTOME:R-HSA-2173791", "REACTOME:R-HSA-420029", "REACTOME:R-MMU-2173791", "REACTOME:R-MMU-420029", "REACTOME:R-MMU-70921", "REACTOME:R-RNO-2173791", "REACTOME:R-RNO-420029", "REACTOME:R-RNO-70921" ]

10

[ "2ns5", "3zee", "4i6p" ]

3

[ "PUB00085056" ]

[ "23643951" ]

[ "Structural insights into the intrinsic self-assembly of Par-3 N-terminal domain." ]

[ 2013 ]

1

[]

0

null

[ "Eukaryota" ]

[ 6163 ]

1

[ "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Homo sapiens", "Mus musculus", "Rattus norvegicus" ]

[ 6, 21, 5, 8, 26, 18 ]

6

true

Domain

Par3/HAL, N-terminal

Par3/HAL_N

5

IPR021923

21,923

Protein of unknown function DUF3536

DUF3536

Family

854

false

This presumed domain is functionally uncharacterised. This domain is found in bacteria and archaea. This domain is typically between 274 to 285 amino acids in length. This domain is found associated with .

[]

0

[ "PFAM" ]

[ "PF12055" ]

[ "DUF3536" ]

[ 854 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Archaea", "Bacteria", "Eukaryota", "ecological metagenomes" ]

[ 43, 789, 2, 20 ]

4

[]

0

true

Family

Protein of unknown function DUF3536

DUF3536

9

IPR021924

21,924

Protein of unknown function DUF3537

DUF3537

Family

3,129

false

This family of transmembrane proteins are functionally uncharacterised. This protein is found in plants. Proteins in this family are typically between 427 to 453 amino acids in length.

[]

0

[ "PFAM", "PANTHER" ]

[ "PF12056", "PTHR31963" ]

[ "DUF3537", "" ]

[ 3129, 3034 ]

2

[]

0

[]

0

[]

0

[]

0

null

[ "Viridiplantae" ]

[ 3129 ]

1

[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 48, 15, 14 ]

3

true

Family

Protein of unknown function DUF3537

DUF3537

5

IPR021925

21,925

Large proline-rich protein BAG6

BAG6

Domain

2,685

false

This domain is found in large proline-rich protein BAG6 protein. It has a conserved SDL sequence motif.

[]

0

[ "PFAM" ]

[ "PF12057" ]

[ "BAG6" ]

[ 2685 ]

1

[ "REACTOME" ]

[ "R-HSA-9609523" ]

[ "REACTOME:R-HSA-9609523" ]

1

[]

0

[ "PUB00086005", "PUB00086006", "PUB00086007", "PUB00086008" ]

[ "21636303", "20516149", "21743475", "28104892" ]

[ "A ubiquitin ligase-associated chaperone holdase maintains polypeptides in soluble states for proteasome degradation.", "Bat3 promotes the membrane integration of tail-anchored proteins.", "Protein targeting and degradation are coupled for elimination of mislocalized proteins.", "Mechanistic basis for a molec...

[ 2011, 2010, 2011, 2017 ]

4

[]

0

null

[ "Metazoa" ]

[ 2685 ]

1

[ "Danio rerio", "Drosophila melanogaster", "Homo sapiens", "Mus musculus", "Rattus norvegicus" ]

[ 9, 11, 14, 8, 12 ]

5

true

Domain

Large proline-rich protein BAG6

BAG6

7

IPR021926

21,926

PII-interacting protein X, cyanobacteria

PipX

Family

372

false

This protein family is predominantly found in cyanobacteria and includes PII-interacting protein X (PipX) from Synechococcus elongatus . PipX modulates the expression of genes involved in nitrogen assimilation by interacting with the global nitrogen transcription factor NtcA and the signal transduction protein PII. It ...

[]

0

[ "NCBIFAM", "PFAM" ]

[ "NF045912", "PF12058" ]

[ "TransCoactPipX", "PipX" ]

[ 306, 372 ]

2

[]

0

[ "2xg8", "2xko", "3n5b", "9guj", "9guk" ]

5

[ "PUB00054483", "PUB00100697", "PUB00100698" ]

[ "20716687", "24912181", "16796668" ]

[ "Structural basis for the regulation of NtcA-dependent transcription by proteins PipX and PII.", "PipX, the coactivator of NtcA, is a global regulator in cyanobacteria.", "Interaction network in cyanobacterial nitrogen regulation: PipX, a protein that interacts in a 2-oxoglutarate dependent manner with PII and ...

[ 2010, 2014, 2006 ]

3

[]

0

null

[ "Cyanobacteriota" ]

[ 372 ]

1

[]

0

true

Family

PII-interacting protein X, cyanobacteria

PipX

9

IPR021927

21,927

Protein of unknown function DUF3540

DUF3540

Family

871

false

This family of proteins is functionally uncharacterised. This protein is found in bacteria. Proteins in this family are typically between 212 to 238 amino acids in length. This protein has a conserved SCL sequence motif.

[]

0

[ "PFAM" ]

[ "PF12059" ]

[ "DUF3540" ]

[ 871 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Protostomia", "metagenomes" ]

[ 861, 2, 8 ]

3

[]

0

true

Family

Protein of unknown function DUF3540

DUF3540

7

IPR021928

21,928

Protein of unknown function DUF3541

DUF3541

Family

519

false

This entry represents a group of uncharacterised proteins mainly found in proteobacteria.

[]

0

[ "PFAM" ]

[ "PF12060" ]

[ "DUF3541" ]

[ 519 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Alexandrium catenella", "Bacteria" ]

[ 1, 518 ]

2

[]

0

true

Family

Protein of unknown function DUF3541

DUF3541

9

IPR021929

21,929

Late blight resistance protein R1A-like, N-terminal

R1A-like_N

Domain

1,061

false

R1 is a gene for resistance to late blight, the most destructive disease in potato cultivation worldwide. The R1 gene belongs to the class of plant genes for pathogen resistance that have a leucine zipper motif, a putative nucleotide binding domain and a leucine-rich repeat domain [ ]. This entry represents the LRR dom...

[]

0

[ "PFAM" ]

[ "PF12061" ]

[ "NB-LRR" ]

[ 1061 ]

1

[]

0

[]

0

[ "PUB00053797" ]

[ "12000683" ]

[ "The R1 gene for potato resistance to late blight (Phytophthora infestans) belongs to the leucine zipper/NBS/LRR class of plant resistance genes." ]

[ 2002 ]

1

[]

0

null

[ "lamiids" ]

[ 1061 ]

1

[]

0

true

Domain

Late blight resistance protein R1A-like, N-terminal

R1A-like_N

7

IPR021930

21,930

Heparan sulphate-N-deacetylase, deacetylase domain

Heparan_SO4_deacetylase_dom

Domain

5,562

false

This domain is found in heparan sulphate N-deacetylase enzymes. It is often found associated with . This entry represents the deacetylase domain which has a fold closely related to the CE domain of Agd3 from A. fumigatus [ ].

[ "GO:0015016", "GO:0016787" ]

[ "heparan sulfate N-sulfotransferase activity", "hydrolase activity" ]

[ "molecular_function", "molecular_function" ]

2

[ "PFAM" ]

[ "PF12062" ]

[ "HSNSD-CE" ]

[ 5562 ]

1

[ "EC", "EC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "METACYC", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME" ]

[ "2.8.2.-", "2.8.2.8", "PWY-6546", "PWY-6558", "PWY-6567", "PWY-6568", "PWY-7831", "PWY-8045", "PWY-8358", "PWY-8381", "R-CEL-2022928", "R-DME-2022928", "R-HSA-2022928", "R-MMU-2022928", "R-RNO-2022928" ]

[ "EC:2.8.2.-", "EC:2.8.2.8", "METACYC:PWY-6546", "METACYC:PWY-6558", "METACYC:PWY-6567", "METACYC:PWY-6568", "METACYC:PWY-7831", "METACYC:PWY-8045", "METACYC:PWY-8358", "METACYC:PWY-8381", "REACTOME:R-CEL-2022928", "REACTOME:R-DME-2022928", "REACTOME:R-HSA-2022928", "REACTOME:R-MMU-2022928"...

15

[ "8ccy", "8cd0", "8chs", "9f6z" ]

4

[ "PUB00159906" ]

[ "38351061" ]

[ "Structural and mechanistic characterization of bifunctional heparan sulfate N-deacetylase-N-sulfotransferase 1." ]

[ 2024 ]

1

[]

0

null

[ "Actinomycetes", "Metazoa" ]

[ 2, 5560 ]

2

[ "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Homo sapiens", "Mus musculus", "Rattus norvegicus" ]

[ 1, 29, 3, 12, 9, 14 ]

6

true

Domain

Heparan sulphate-N-deacetylase, deacetylase domain

Heparan_SO4_deacetylase_dom

9

IPR021931

21,931

MYND-type zinc finger-containing chromatin reader ZMYND8

ZMYND8

Family

3,730

false

This family represents protein kinase C-binding protein 1 (PRKCBP1, also known as ZMYND8) from vertebrates, a chromatin reader that recognises dual histone modifications such as histone H3.1 dimethylated at 'Lys-36' and histone H4 acetylated at 'Lys-16' (H3.1K36me2-H4K16ac) and histone H3 methylated at 'Lys-4' and hist...

[]

0

[ "PFAM" ]

[ "PF12064" ]

[ "DUF3544" ]

[ 3730 ]

1

[]

0

[]

0

[ "PUB00085454", "PUB00103298", "PUB00103632", "PUB00103633", "PUB00103634", "PUB00103635", "PUB00103636", "PUB00103688" ]

[ "27477906", "30134174", "36064715", "31965980", "33323928", "25593309", "27732854", "35916866" ]

[ "ZMYND8 Reads the Dual Histone Mark H3K4me1-H3K14ac to Antagonize the Expression of Metastasis-Linked Genes.", "Positive Regulation of Transcription by Human ZMYND8 through Its Association with P-TEFb Complex.", "ZMYND8 suppresses MAPT213 LncRNA transcription to promote neuronal differentiation.", "A novel ro...

[ 2016, 2018, 2022, 2020, 2020, 2015, 2016, 2022 ]

8

[]

0

null

[ "Vertebrata" ]

[ 3730 ]

1

[ "Danio rerio", "Homo sapiens", "Mus musculus", "Rattus norvegicus" ]

[ 23, 7, 15, 10 ]

4

true

Family

MYND-type zinc finger-containing chromatin reader ZMYND8

ZMYND8

8

IPR021932

21,932

Protein of unknown function DUF3545

DUF3545

Family

716

false

This family of proteins is functionally uncharacterised. This protein is found in bacteria. Proteins in this family are typically between 60 to 77 amino acids in length. This protein has two completely conserved residues (R and L) that may be functionally important.

[]

0

[ "PFAM" ]

[ "PF12065" ]

[ "DUF3545" ]

[ 716 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "marine sediment metagenome" ]

[ 715, 1 ]

2

[]

0

true

Family

Protein of unknown function DUF3545

DUF3545

2

IPR021934

21,934

Sox, C-terminal

Sox_C

Domain

2,536

false

The Sox transcription factors are members of the Sry-related protein family that play multiple roles, mainly during development. Sox18, together with Sox7 and -17, constitutes the subgroup F within this family. Sox18 contains three major domains:the N-terminal HMG box, the central TAD domain and the C-terminal domain t...

[]

0

[ "PROFILE" ]

[ "PS51516" ]

[ "SOX_C" ]

[ 2536 ]

1

[ "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME" ]

[ "R-HSA-3769402", "R-HSA-9823730", "R-HSA-9827857", "R-HSA-9937080", "R-MMU-3769402", "R-XTR-3769402" ]

[ "REACTOME:R-HSA-3769402", "REACTOME:R-HSA-9823730", "REACTOME:R-HSA-9827857", "REACTOME:R-HSA-9937080", "REACTOME:R-MMU-3769402", "REACTOME:R-XTR-3769402" ]

6

[]

0

[ "PUB00055525", "PUB00075852", "PUB00075853" ]

[ "17603017", "24460943", "17467953" ]

[ "A novel 9-amino-acid transactivation domain in the C-terminal part of Sox18.", "Construction and functional analysis of novel dominant-negative mutant of human SOX18 protein.", "Nine-amino-acid transactivation domain: establishment and prediction utilities." ]

[ 2007, 2013, 2007 ]

3

[]

0

null

[ "Bacteria", "Eukaryota", "Halobacteriales", "marine sediment metagenome" ]

[ 83, 2450, 2, 1 ]

4

[ "Arabidopsis thaliana", "Danio rerio", "Homo sapiens", "Mus musculus", "Rattus norvegicus" ]

[ 2, 2, 7, 6, 7 ]

5

true

Domain

Sox, C-terminal

Sox_C

9

IPR021935

21,935

Small G protein signalling modulator 1/2, Rab-binding domain

SGSM1/2_RBD

Domain

8,503

false

This domain adopts a PH-like fold. It has been called the Rab-binding domain (RBD) [ ]. Small G-protein signalling modulator 1/2 (also known as RUTBC2/1) bind to Rab9A via their Pleckstrin homology (PH) domain [ , ]. RUTBC1 stimulates GTP hydrolysis by Rab32 and Rab33B [ ], while RUTBC2 appears to be a GAP for Rab36, R...

[]

0

[ "PFAM" ]

[ "PF12068" ]

[ "PH_RBD" ]

[ 8503 ]

1

[ "REACTOME", "REACTOME", "REACTOME" ]

[ "R-HSA-8854214", "R-MMU-8854214", "R-SPO-8854214" ]

[ "REACTOME:R-HSA-8854214", "REACTOME:R-MMU-8854214", "REACTOME:R-SPO-8854214" ]

3

[ "4qxa" ]

1

[ "PUB00086312", "PUB00087560", "PUB00087561", "PUB00087562" ]

[ "17509819", "22637480", "26620560", "25220469" ]

[ "Identification of three novel proteins (SGSM1, 2, 3) which modulate small G protein (RAP and RAB)-mediated signaling pathway.", "RUTBC2 protein, a Rab9A effector and GTPase-activating protein for Rab36.", "RUTBC1 Functions as a GTPase-activating Protein for Rab32/38 and Regulates Melanogenic Enzyme Trafficking...

[ 2007, 2012, 2016, 2014 ]

4

[]

[ "IPR037745" ]

0

1

0

[ "Eukaryota" ]

[ 8503 ]

1

[ "Arabidopsis thaliana", "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Homo sapiens", "Mus musculus", "Oryza sativa subsp. japonica", "Rattus norvegicus", "Schizosaccharomyces pombe (strain 972 / ATCC 24843)", "Zea mays" ]

[ 7, 3, 15, 3, 14, 17, 2, 18, 1, 9 ]

10

true

Domain

Small G protein signalling modulator 1/2, Rab-binding domain

SGSM1/2_RBD

3

IPR021936

21,936

Protein of unknown function DUF3549

DUF3549

Family

1,210

false

This family of proteins is functionally uncharacterised. This protein is found in bacteria. Proteins in this family are about 340 amino acids in length. This protein has a conserved LDE sequence motif.

[]

0

[ "PFAM" ]

[ "PF12069" ]

[ "DUF3549" ]

[ 1210 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "ecological metagenomes" ]

[ 1197, 13 ]

2

[]

0

true

Family

Protein of unknown function DUF3549

DUF3549

1

IPR021937

21,937

Protein of unknown function DUF3551

DUF3551

Family

948

false

This family of proteins is functionally uncharacterised. This protein is found in bacteria. Proteins in this family are typically between 79 to 104 amino acids in length. This protein has a single completely conserved residue C that may be functionally important.

[]

0

[ "PFAM" ]

[ "PF12071" ]

[ "DUF3551" ]

[ 948 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Chiloscyllium punctatum", "Pseudomonadota" ]

[ 1, 947 ]

2

[]

0

true

Family

Protein of unknown function DUF3551

DUF3551

8

IPR021938

21,938

Protein of unknown function DUF3553

DUF3553

Family

1,380

false

This family of proteins is functionally uncharacterised. This protein is found in bacteria. Proteins in this family are about 60 amino acids in length. This protein has two conserved sequence motifs: GQVQS and TVNF.

[]

0

[ "PFAM" ]

[ "PF12073" ]

[ "DUF3553" ]

[ 1380 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Durusdinium trenchii", "unclassified sequences" ]

[ 1366, 1, 13 ]

3

[]

0

true

Family

Protein of unknown function DUF3553

DUF3553

3

IPR021940

21,940

Very-long-chain aldehyde decarbonylase CER1-like, C-terminal

CER1-like_C

Domain

3,774

false

Very-long-chain aldehyde decarbonylase CER1 is an aldehyde decarbonylase involved in the conversion of aldehydes to alkanes. It is the core component of a very-long-chain alkane synthesis complex and it is involved in epicuticular wax biosynthesis and pollen fertility. CER1 is also linked to responses to biotic and abi...

[]

0

[ "PFAM" ]

[ "PF12076" ]

[ "CER1-like_C" ]

[ 3774 ]

1

[ "EC", "METACYC", "METACYC", "METACYC" ]

[ "4.1.99.5", "PWY-282", "PWY-6622", "PWY-7032" ]

[ "EC:4.1.99.5", "METACYC:PWY-282", "METACYC:PWY-6622", "METACYC:PWY-7032" ]

4

[]

0

[ "PUB00004521", "PUB00053556", "PUB00101827", "PUB00101828", "PUB00101829" ]

[ "8718622", "12724542", "21386033", "22773744", "36110041" ]

[ "Molecular characterization of the CER1 gene of arabidopsis involved in epicuticular wax biosynthesis and pollen fertility.", "Cloning and characterization of the WAX2 gene of Arabidopsis involved in cuticle membrane and wax production.", "Overexpression of Arabidopsis ECERIFERUM1 promotes wax very-long-chain a...

[ 1995, 2003, 2011, 2012, 2022 ]

5

[]

0

null

[ "Bacteria", "Eukaryota" ]

[ 4, 3770 ]

2

[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 23, 12, 61 ]

3

true

Domain

Very-long-chain aldehyde decarbonylase CER1-like, C-terminal

CER1-like_C

4

IPR021942

21,942

Protein of unknown function DUF3557

DUF3557

Family

2,003

false

This presumed domain is functionally uncharacterised. This domain is found in eukaryotes. This domain is about 150 amino acids in length.

[]

0

[ "PFAM", "PANTHER" ]

[ "PF12078", "PTHR31379" ]

[ "DUF3557", "" ]

[ 1616, 1973 ]

2

[]

0

[]

0

[]

0

[]

0

null

[ "Rhabditomorpha" ]

[ 2003 ]

1

[ "Caenorhabditis elegans" ]

[ 52 ]

1

true

Family

Protein of unknown function DUF3557

DUF3557

4

IPR021944

21,944

Protein of unknown function DUF3560

DUF3560

Family

1,336

false

This presumed domain is functionally uncharacterised. This domain is found in bacteria. This domain is about 120 amino acids in length. This domain has a conserved GHHSE sequence motif.

[]

0

[ "PFAM" ]

[ "PF12083" ]

[ "DUF3560" ]

[ 1336 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Eukaryota", "Viruses", "metagenomes" ]

[ 1310, 2, 9, 15 ]

4

[]

0

true

Family

Protein of unknown function DUF3560

DUF3560

2

IPR021945

21,945

Protein of unknown function DUF3562

DUF3562

Family

419

false

This family of proteins is functionally uncharacterised. This protein is found in bacteria. Proteins in this family are typically between 62 to 84 amino acids in length. This protein has two completely conserved residues (A and Y) that may be functionally important.

[]

0

[ "PFAM" ]

[ "PF12085" ]

[ "DUF3562" ]

[ 419 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "hydrothermal vent metagenome" ]

[ 418, 1 ]

2

[]

0

true

Family

Protein of unknown function DUF3562

DUF3562

4

IPR021946

21,946

Protein of unknown function DUF3563

DUF3563

Family

890

false

This family of proteins is functionally uncharacterised. This protein is found in bacteria. Proteins in this family are about 50 amino acids in length. This protein has conserved AYL and DLE sequence motifs.

[]

0

[ "PFAM" ]

[ "PF12086" ]

[ "DUF3563" ]

[ 890 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Pseudomonadota", "ecological metagenomes" ]

[ 880, 10 ]

2

[]

0

true

Family

Protein of unknown function DUF3563

DUF3563

6

IPR021947

21,947

Protein of unknown function DUF3564

DUF3564

Family

454

false

This family of proteins is functionally uncharacterised. This protein is found in bacteria. Proteins in this family are typically between 118 to 142 amino acids in length. This protein has a conserved WSRE sequence motif.

[]

0

[ "PFAM" ]

[ "PF12087" ]

[ "DUF3564" ]

[ 454 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Burkholderiaceae", "Ricinus communis" ]

[ 453, 1 ]

2

[]

0

true

Family

Protein of unknown function DUF3564

DUF3564

1

IPR021950

21,950

Transcription factor Spt20

Spt20

Family

5,474

false

This entry represents the Spt20 transcription factors in eukaryote organisms. The Spt20 protein is a subunit of the SAGA (Spt-Ada-Gcn5-acetyltransferase) complex, a large multiprotein complex involved in transcriptional regulation. In yeast, Spt20 plays a crucial role in maintaining the structural integrity of the SAGA...

[ "GO:0003712", "GO:0000124" ]

[ "transcription coregulator activity", "SAGA complex" ]

[ "molecular_function", "cellular_component" ]

2

[ "PANTHER" ]

[ "PTHR13526" ]

[ "" ]

[ 5474 ]

1

[ "GP", "REACTOME" ]

[ "GenProp2053", "R-HSA-3214847" ]

[ "GP:GenProp2053", "REACTOME:R-HSA-3214847" ]

2

[ "6t9i", "6t9j", "6t9k", "6tb4", "6tbm", "7ktr", "7kts", "8h7g" ]

8

[ "PUB00062949", "PUB00095265", "PUB00101214", "PUB00101215", "PUB00101216" ]

[ "10026213", "19056896", "31969704", "31969703", "19114550" ]

[ "Expanded lysine acetylation specificity of Gcn5 in native complexes.", "The S. pombe SAGA complex controls the switch from proliferation to sexual differentiation through the opposing roles of its subunits Gcn5 and Spt8.", "Structure of SAGA and mechanism of TBP deposition on gene promoters.", "Structure of ...

[ 1999, 2008, 2020, 2020, 2009 ]

5

[]

0

null

[ "Eukaryota", "Pseudorhodoferax aquiterrae" ]

[ 5473, 1 ]

2

[ "Arabidopsis thaliana", "Danio rerio", "Drosophila melanogaster", "Homo sapiens", "Mus musculus", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Oryza sativa subsp. japonica", "Rattus norvegicus", "Saccharomyces cerevisiae (strain ATCC 204508 / S288c)", "...

[ 6, 25, 2, 11, 8, 1, 7, 17, 1, 1, 12 ]

11

true

Family

Transcription factor Spt20

Spt20

8

IPR021951

21,951

Protein of unknown function DUF3567

DUF3567

Family

891

false

This family of proteins is functionally uncharacterised. This protein is found in bacteria. Proteins in this family are about 90 amino acids in length. This protein has a conserved EIVDK sequence motif.

[]

0

[ "NCBIFAM", "PFAM" ]

[ "NF050004", "PF12091" ]

[ "BTH_I0359_fam", "DUF3567" ]

[ 836, 891 ]

2

[]

0

[]

0

[ "PUB00159082" ]

[ "25786241" ]

[ "Genetic analysis of the CDI pathway from Burkholderia pseudomallei 1026b." ]

[ 2015 ]

1

[]

0

null

[ "Pseudomonadati", "ecological metagenomes" ]

[ 885, 6 ]

2

[]

0

true

Family

Protein of unknown function DUF3567

DUF3567

8

IPR021952

21,952

Lipoprotein Flpp3-like

Flpp3-like

Family

406

false

This entry represents a family of bacterial proteins, including the outer membrane lipoprotein Flpp3 from Francisella tularensis ( ). This protein family was previously known as DUF3568. Flpp3, a virulence determinant of tularemia, shows a six stranded β-sheet supported with two crossing α-helices. It has a hydrophobic...

[]

0

[ "PFAM" ]

[ "PF12092" ]

[ "DUF3568" ]

[ 406 ]

1

[]

0

[ "2mu4", "6pny", "9nlt" ]

3

[ "PUB00100865", "PUB00100866" ]

[ "26004443", "32142641" ]

[ "NMR Structure of Francisella tularensis Virulence Determinant Reveals Structural Homology to Bet v1 Allergen Proteins.", "XFEL and NMR Structures of Francisella Lipoprotein Reveal Conformational Space of Drug Target against Tularemia." ]

[ 2015, 2020 ]

2

[]

0

null

[ "Bacteria", "ecological metagenomes" ]

[ 395, 11 ]

2

[]

0

true

Family

Lipoprotein Flpp3-like

Flpp3-like

9

IPR021953

21,953

Protein of unknown function DUF3570

DUF3570

Family

1,805

false

This family of bacterial proteins is functionally uncharacterised. Proteins in this family are typically between 396 to 444 amino acids in length. Members in this family contain the conserved [S/T]GA[S/T] motif and are flavinylation substrates for ApbE, which suggests that they may be involved in extra cytosolic redox ...

[]

0

[ "PFAM" ]

[ "PF12094" ]

[ "DUF3570" ]

[ 1805 ]

1

[]

0

[]

0

[ "PUB00098250" ]

[ "34032212" ]

[ "Post-translational flavinylation is associated with diverse extracytosolic redox functionalities throughout bacterial life." ]

[ 2021 ]

1

[]

0

null

[ "Bacteria", "Symbiodinium", "ecological metagenomes" ]

[ 1749, 2, 54 ]

3

[]

0

true

Family

Protein of unknown function DUF3570

DUF3570

7

IPR021954

21,954

Protein CHLORORESPIRATORY REDUCTION 7

CRR7

Family

875

false

This entry includes protein from cyanobacteria, blue-green algae and plants, including CRR7 (Chlororespiratory reduction 7) protein from Arabidopsis. CRR7 is part of the chloroplastic NAD(P)H dehydrogenase complex (NDH Complex) involved in respiration, photosystem I (PSI) cyclic electron transport and CO2 uptake [ ]. I...

[]

0

[ "PFAM", "PANTHER" ]

[ "PF12095", "PTHR36803" ]

[ "CRR7", "" ]

[ 875, 799 ]

2

[]

0

[ "2krx" ]

1

[ "PUB00075318", "PUB00100355", "PUB00163389", "PUB00163390" ]

[ "16359395", "22274627", "22113821", "27208268" ]

[ "Identification of a novel protein, CRR7, required for the stabilization of the chloroplast NAD(P)H dehydrogenase complex in Arabidopsis.", "Multistep assembly of chloroplast NADH dehydrogenase-like subcomplex A requires several nucleus-encoded proteins, including CRR41 and CRR42, in Arabidopsis.", "Solution NM...

[ 2005, 2012, 2012, 2016 ]

4

[]

0

null

[ "Cyanobacteriota", "Eukaryota" ]

[ 365, 510 ]

2

[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 3, 2, 5 ]

3

true

Family

Protein CHLORORESPIRATORY REDUCTION 7

CRR7

3

IPR021955

21,955

Protein of unknown function DUF3572

DUF3572

Family

2,276

false

This family of proteins is functionally uncharacterised. Proteins in this family are about 100 amino acids in length and are found in bacteria.

[]

0

[ "PFAM" ]

[ "PF12096" ]

[ "DUF3572" ]

[ 2276 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "ecological metagenomes" ]

[ 2260, 16 ]

2

[]

0

true

Family

Protein of unknown function DUF3572

DUF3572

2

IPR021956

21,956

Protein of unknown function DUF3573

DUF3573

Family

145

false

This family of proteins is functionally uncharacterised. This protein is found in bacteria. Proteins in this family are typically between 372 to 530 amino acids in length.

[]

0

[ "PFAM" ]

[ "PF12097" ]

[ "DUF3573" ]

[ 145 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Pseudomonadota" ]

[ 145 ]

1

[]

0

true

Family

Protein of unknown function DUF3573

DUF3573

7

IPR021957

21,957

Protein of unknown function DUF3574

DUF3574

Family

1,903

false

This family of proteins is functionally uncharacterised. This protein is found in bacteria and viruses. Proteins in this family are typically between 144 to 163 amino acids in length. This protein has a conserved TPRF sequence motif.

[]

0

[ "PFAM" ]

[ "PF12098" ]

[ "DUF3574" ]

[ 1903 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Archaea", "Bacteria", "Caudoviricetes", "Eukaryota", "metagenomes" ]

[ 4, 1867, 9, 14, 9 ]

5

[]

0

true

Family

Protein of unknown function DUF3574

DUF3574

3

IPR021958

21,958

Protein of unknown function DUF3575

DUF3575

Family

4,374

false

This family of proteins are functionally uncharacterised. This family is only found in bacteria. Proteins in this family are typically between 187 to 236 amino acids in length.

[]

0

[ "PFAM" ]

[ "PF12099" ]

[ "DUF3575" ]

[ 4374 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Viruses", "unclassified sequences" ]

[ 4298, 2, 74 ]

3

[]

0

true

Family

Protein of unknown function DUF3575

DUF3575

7

IPR021959

21,959

Protein of unknown function DUF3576

DUF3576

Family

1,806

false

This presumed domain is functionally uncharacterised. This domain is found in bacteria. This domain is about 100 amino acids in length. This domain has a single completely conserved residue G that may be functionally important.

[]

0

[ "PFAM" ]

[ "PF12100" ]

[ "DUF3576" ]

[ 1806 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Eukaryota", "Pseudomonadati", "metagenomes" ]

[ 8, 1760, 38 ]

3

[]

0

true

Family

Protein of unknown function DUF3576

DUF3576

1

IPR021960

21,960

Protein of unknown function DUF3577

DUF3577

Family

1,674

false

This family of proteins is functionally uncharacterised. This protein is found in bacteria. Proteins in this family are typically between 143 to 307 amino acids in length. Members of this family regularly are found near a TopB family topoisomerase, in mobile elements such as certain pathogenicity islands, in regions of...

[]

0

[ "NCBIFAM", "PFAM" ]

[ "NF040584", "PF12101" ]

[ "STY4534_fam", "DUF3577" ]

[ 1121, 1674 ]

2

[]

0

[]

0

[ "PUB00105841" ]

[ "22247511" ]

[ "Structure, diversity, and mobility of the Salmonella pathogenicity island 7 family of integrative and conjugative elements within Enterobacteriaceae." ]

[ 2012 ]

1

[]

0

null

[ "Bacteria", "Eukaryota", "metagenomes" ]

[ 1655, 5, 14 ]

3

[]

0

true

Family

Protein of unknown function DUF3577

DUF3577

2

IPR021961

21,961

Type IV methyl-directed restriction enzyme EcoKMcrB subunit, DNA-binding domain

McrB_DNA-bd

Domain

1,117

false

This entry represents the DNA-binding domain found at the N-terminal of Type IV methyl-directed restriction enzyme EcoKMcrB subunit (mcrB, also known as 5-methylcytosine-specific restriction enzyme B McrB) from E. coli [ , ]. McrB recognises N4- and C5-methylcytosine (and 5-hydroxy-methylcytosines) produced by a broad ...

[]

0

[ "PFAM" ]

[ "PF12102" ]

[ "MrcB_N" ]

[ 1117 ]

1

[]

0

[ "3ssc", "3ssd", "3sse", "6gcd", "6gce", "6gcf", "6ut6", "7vsr", "8ijo", "8ijp", "8ik4", "8ik8", "8ikd" ]

13

[ "PUB00070724", "PUB00100345", "PUB00100346" ]

[ "7781618", "30194838", "22570415" ]

[ "McrB: a prokaryotic protein specifically recognizing DNA containing modified cytosine residues.", "Recognition of modified cytosine variants by the DNA-binding domain of methyl-directed endonuclease McrBC.", "The recognition domain of the methyl-specific endonuclease McrBC flips out 5-methylcytosine." ]

[ 1995, 2018, 2012 ]

3

[]

0

null

[ "Archaea", "Bacteria", "Eukaryota", "ecological metagenomes" ]

[ 44, 1042, 21, 10 ]

4

[ "Escherichia coli (strain K12)" ]

[ 1 ]

1

true

Domain

Type IV methyl-directed restriction enzyme EcoKMcrB subunit, DNA-binding domain

McrB_DNA-bd

4

IPR021963

21,963

T cell CD4 receptor C-terminal region

Tcell_CD4_Cterm

Domain

977

false

This domain is the C-terminal domain of the CD4 T cell receptor. The C-terminal domain is the cytoplasmic domain which relays the signal for T cell activation. This process involves co-receptor internalisation. This domain is involved in binding to the N-terminal of Lck co-receptor in a Zn2+ clasp structure.

[]

0

[ "PFAM" ]

[ "PF12104" ]

[ "Tcell_CD4_C" ]

[ 977 ]

1

[ "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOM...

[ "R-CFA-202424", "R-CFA-202427", "R-CFA-202430", "R-CFA-202433", "R-CFA-389948", "R-CFA-449836", "R-CFA-8856825", "R-CFA-8856828", "R-HSA-1462054", "R-HSA-167590", "R-HSA-173107", "R-HSA-180534", "R-HSA-202424", "R-HSA-202427", "R-HSA-202430", "R-HSA-202433", "R-HSA-389948", "R-HSA-...

[ "REACTOME:R-CFA-202424", "REACTOME:R-CFA-202427", "REACTOME:R-CFA-202430", "REACTOME:R-CFA-202433", "REACTOME:R-CFA-389948", "REACTOME:R-CFA-449836", "REACTOME:R-CFA-8856825", "REACTOME:R-CFA-8856828", "REACTOME:R-HSA-1462054", "REACTOME:R-HSA-167590", "REACTOME:R-HSA-173107", "REACTOME:R-HSA-...

38

[ "1q68", "1wbr", "2klu", "3b71", "3reb", "6uri" ]

6

[]

0

[]

0

null

[ "Bacteria", "Eukaryota", "Pandoravirus", "freshwater metagenome" ]

[ 14, 959, 3, 1 ]

4

[ "Homo sapiens", "Mus musculus", "Rattus norvegicus" ]

[ 5, 4, 4 ]

3

true

Domain

T cell CD4 receptor C-terminal region

Tcell_CD4_Cterm

9

IPR021964

21,964

Colicin E5 ribonuclease domain

Colicin_E5_C

Domain

150

false

Colicin is a protein produced by bacteria with Col plasmids. Its function is to attack Escherichia coli through actions on its inner membrane ion channels or through ribonuclease or deoxyribonuclease actions. The C-terminal domain is the ribonuclease domain. Colicin E5 specifically cleaves tRNA anticodons which recogni...

[ "GO:0004540" ]

[ "RNA nuclease activity" ]

[ "molecular_function" ]

1

[ "PFAM" ]

[ "PF12106" ]

[ "Colicin_E5" ]

[ 150 ]

1

[]

0

[ "2a8k", "2dfx", "2djh", "2fhz", "3ao9", "3vj7" ]

6

[ "PUB00040245" ]

[ "17099236" ]

[ "Structural basis for sequence-dependent recognition of colicin E5 tRNase by mimicking the mRNA-tRNA interaction." ]

[ 2006 ]

1

[]

0

null

[ "Bacteria", "Syphacia muris", "metagenomes" ]

[ 146, 1, 3 ]

3

[]

0

true

Domain

Colicin E5 ribonuclease domain

Colicin_E5_C

9

IPR021965

21,965

Plasminogen ligand, VEK-30

Plasminogen_ligand_VEK-30

Domain

124

false

Pg is an important mediator of angiostatin production in the fibrinolytic pathway. Pg is made up of five subunit kringle molecules (Pg-K1 to Pg-K5), of which the first three make the protein angiostatin. VEK-30 is a domain of the group A streptococcal protein PAM. It binds to Pg-K2 of angiostatin and activates the mole...

[]

0

[ "PFAM" ]

[ "PF12107" ]

[ "VEK-30" ]

[ 124 ]

1

[]

0

[ "1i5k", "2doh", "2doi", "2kj4", "5v4u", "6bzj", "6bzk", "6bzl", "6og4", "6okw", "6okx", "6oky", "6oq9", "6oqj", "6oqk", "6uz4", "6uz5", "8tvl" ]

18

[ "PUB00040274" ]

[ "16964966" ]

[ "X-ray crystallographic structure of the angiogenesis inhibitor, angiostatin, bound to a peptide from the group A streptococcal surface protein PAM." ]

[ 2006 ]

1

[]

0

null

[ "Bacteria" ]

[ 124 ]

1

[]

0

true

Domain

Plasminogen ligand, VEK-30

Plasminogen_ligand_VEK-30

3

IPR021966

21,966

Splicing factor SF3a60 binding domain

SF3a60_bindingd

Domain

3,971

false

This domain is found in eukaryotes. This domain is about 30 amino acids in length. This domain has a single completely conserved residue Y that may be functionally important. SF3a60 makes up the SF3a complex with SF3a66 and SF3a120. This domain is the binding site of SF3a60 for SF3a120. The SF3a complex is part of the ...

[]

0

[ "PFAM" ]

[ "PF12108" ]

[ "SF3a60_bindingd" ]

[ 3971 ]

1

[ "REACTOME", "REACTOME" ]

[ "R-HSA-72163", "R-MMU-72163" ]

[ "REACTOME:R-HSA-72163", "REACTOME:R-MMU-72163" ]

2

[ "2dt7", "5z56", "5z57", "5z58", "6ah0", "6ahd", "6ff7", "6qx9", "6y50", "6y53", "6y5q", "7abg", "7abh", "7abi", "7evo", "7onb", "7q3l", "7q4o", "7q4p", "7qtt", "7vpx", "8ch6", "8h6e", "8h6j", "8h6k", "8h6l", "8hk1", "8i0p", "8i0r", "8i0s", "8i0t", "8i0u"...

40

[]

0

[]

0

null

[ "Eukaryota" ]

[ 3971 ]

1

[ "Arabidopsis thaliana", "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Homo sapiens", "Mus musculus", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Oryza sativa subsp. japonica", "Rattus norvegicus", "Schizosaccharomyces pombe (stra...

[ 3, 1, 1, 1, 5, 2, 1, 2, 4, 1, 7 ]

11

true

Domain

Splicing factor SF3a60 binding domain

SF3a60_bindingd

5

IPR021967

21,967

Nuclear pore complex protein NUP96, C-terminal domain

Nup98_C

Domain

5,446

false

This entry represents the Nuclear pore complex protein Nup96 from animals its homologues from yeast and plants. Nuclear pore complexes (NPCs) facilitate all nucleocytoplasmic transport in eukaryotic cells, playing essential roles in cellular homeostasis. The NPC is a modular structure composed of multiple copies of ~30...

[]

0

[ "PFAM" ]

[ "PF12110" ]

[ "Nup96" ]

[ 5446 ]

1

[ "EC", "METACYC", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "...

[ "3.4.21.-", "PWY-7884", "R-CEL-9615933", "R-DME-159227", "R-DME-159230", "R-DME-159231", "R-DME-159236", "R-DME-170822", "R-DME-3108214", "R-DME-3301854", "R-DME-4085377", "R-DME-4551638", "R-DME-4615885", "R-DME-5578749", "R-DME-9615933", "R-HSA-1169408", "R-HSA-141444", "R-HSA-15...

[ "EC:3.4.21.-", "METACYC:PWY-7884", "REACTOME:R-CEL-9615933", "REACTOME:R-DME-159227", "REACTOME:R-DME-159230", "REACTOME:R-DME-159231", "REACTOME:R-DME-159236", "REACTOME:R-DME-170822", "REACTOME:R-DME-3108214", "REACTOME:R-DME-3301854", "REACTOME:R-DME-4085377", "REACTOME:R-DME-4551638", "R...

104

[ "3bg0", "3bg1", "3iko", "3jro", "4xmm", "4xmn", "4ycz", "5a9q", "6lk8", "7f60", "7f90", "7fik", "7n84", "7n9f", "7peq", "7r5j", "7r5k", "7tbi", "7tbj", "7tbk", "7tbl", "7tbm", "7tdz", "7vci", "7vop", "7wb4", "8tie", "9hcj", "9sob" ]

29

[ "PUB00011902", "PUB00019948", "PUB00039297", "PUB00050622", "PUB00099726", "PUB00099727", "PUB00099728", "PUB00099729", "PUB00099730" ]

[ "12191480", "12191467", "16105837", "18160040", "30943044", "33159083", "33247142", "21326946", "19855394" ]

[ "The three-dimensional structure of the autoproteolytic, nuclear pore-targeting domain of the human nucleoporin Nup98.", "Cleave to leave: structural insights into the dynamic organization of the nuclear pore complex.", "Multiple conformations in the ligand-binding site of the yeast nuclear pore-targeting domai...

[ 2002, 2002, 2005, 2007, 2019, 2020, 2020, 2010, 2009 ]

9

[]

0

null

[ "Eukaryota" ]

[ 5446 ]

1

[ "Arabidopsis thaliana", "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Homo sapiens", "Mus musculus", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Oryza sativa subsp. japonica", "Rattus norvegicus", "Saccharomyces cerevisiae (strai...

[ 4, 1, 2, 7, 11, 2, 1, 4, 2, 1, 1, 14 ]

12

true

Domain

Nuclear pore complex protein NUP96, C-terminal domain

Nup98_C

9