interpro_id string | interpro_numeric_id int64 | name string | short_name string | entry_type string | protein_count int64 | is_llm bool | is_llm_reviewed bool | abstract string | go_ids list | go_terms list | go_categories list | go_count int64 | member_databases list | member_accessions list | member_names list | member_protein_counts list | member_count int64 | external_databases list | external_accessions list | external_xrefs list | external_xref_count int64 | pdb_ids list | structure_count int64 | publication_ids list | pubmed_ids list | publication_titles list | publication_years list | publication_count int64 | parent_ids list | child_ids list | parent_count int64 | child_count int64 | tree_depth float64 | taxonomy_names list | taxonomy_protein_counts list | taxonomy_count int64 | key_species_names list | key_species_protein_counts list | key_species_count int64 | in_entry_list bool | entry_list_type string | entry_list_name string | names_dat_name string | short_names_dat_name string | split_bucket int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
IPR056287 | 56,287 | AIR9, PH-like domain | PH_AIR9 | Domain | 688 | false | false | This is a PH-like domain found at the C-terminal of AIR9 from Arabidopsis thaliana and similar proteins from plants that often have 9/11 repetitions of . It may adopt a partly opened β-barrel topology that is capped by an α-helix. Interaction between AIR9 and POK1 is important for division plane orientation and plant g... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23218"
] | [
"PH_AIR9"
] | [
688
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00155669"
] | [
"36005863"
] | [
"The localization of PHRAGMOPLAST ORIENTING KINESIN1 at the division site depends on the microtubule-binding proteins TANGLED1 and AUXIN-INDUCED IN ROOT CULTURES9 in Arabidopsis."
] | [
2022
] | 1 | [] | [] | 0 | 0 | null | [
"Viridiplantae"
] | [
688
] | 1 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
4,
4,
13
] | 3 | true | Domain | AIR9, PH-like domain | AIR9, PH-like domain | PH_AIR9 | 9 |
IPR056288 | 56,288 | Centrosomal protein of 76 kDa, C-terminal | CEP76_C | Domain | 3,886 | false | false | This entry represents a domain found at the C-terminal of centrosomal protein of 76 kDa, a protein involved in regulation of centriole duplication to limit centriole duplication to once per cell cycle by preventing centriole reduplication [ ]. This domain may adopt a fold similar to the CAP domain. This entry also incl... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF24652"
] | [
"CEP76_C"
] | [
3886
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-HSA-2565942",
"R-HSA-380259",
"R-HSA-380270",
"R-HSA-380284",
"R-HSA-380320",
"R-HSA-5620912",
"R-HSA-8854518",
"R-MMU-2565942",
"R-MMU-380259",
"R-MMU-380270",
"R-MMU-380284",
"R-MMU-380320",
"R-MMU-5620912",
"R-MMU-8854518",
"R-XTR-2565942",
"R-XTR-380259",
"R-XTR-380270",
"R-... | [
"REACTOME:R-HSA-2565942",
"REACTOME:R-HSA-380259",
"REACTOME:R-HSA-380270",
"REACTOME:R-HSA-380284",
"REACTOME:R-HSA-380320",
"REACTOME:R-HSA-5620912",
"REACTOME:R-HSA-8854518",
"REACTOME:R-MMU-2565942",
"REACTOME:R-MMU-380259",
"REACTOME:R-MMU-380270",
"REACTOME:R-MMU-380284",
"REACTOME:R-MMU... | 20 | [] | 0 | [
"PUB00069719",
"PUB00069721",
"PUB00159961",
"PUB00159962"
] | [
"19460342",
"18513680",
"22246776",
"33803212"
] | [
"Cep76, a centrosomal protein that specifically restrains centriole reduplication.",
"Identification of CC2D2A as a Meckel syndrome gene adds an important piece to the ciliopathy puzzle.",
"A DOC2 protein identified by mutational profiling is essential for apicomplexan parasite exocytosis.",
"Ferlins and TgDO... | [
2009,
2008,
2012,
2021
] | 4 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
3886
] | 1 | [
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
19,
1,
7,
4,
10
] | 5 | true | Domain | Centrosomal protein of 76 kDa, C-terminal | Centrosomal protein of 76 kDa, C-terminal | CEP76_C | 8 |
IPR056289 | 56,289 | CEP76, N-terminal | CEP76_N | Domain | 1,262 | false | false | This entry represents a domain found at the N-terminal of centrosomal protein of 76 kDa, a protein involved in regulation of centriole duplication to limit centriole duplication to once per cell cycle by preventing centriole reduplication [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF24654"
] | [
"CEP76_N"
] | [
1262
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-HSA-2565942",
"R-HSA-380259",
"R-HSA-380270",
"R-HSA-380284",
"R-HSA-380320",
"R-HSA-5620912",
"R-HSA-8854518",
"R-MMU-2565942",
"R-MMU-380259",
"R-MMU-380270",
"R-MMU-380284",
"R-MMU-380320",
"R-MMU-5620912",
"R-MMU-8854518",
"R-XTR-2565942",
"R-XTR-380259",
"R-XTR-380270",
"R-... | [
"REACTOME:R-HSA-2565942",
"REACTOME:R-HSA-380259",
"REACTOME:R-HSA-380270",
"REACTOME:R-HSA-380284",
"REACTOME:R-HSA-380320",
"REACTOME:R-HSA-5620912",
"REACTOME:R-HSA-8854518",
"REACTOME:R-MMU-2565942",
"REACTOME:R-MMU-380259",
"REACTOME:R-MMU-380270",
"REACTOME:R-MMU-380284",
"REACTOME:R-MMU... | 20 | [] | 0 | [
"PUB00069719"
] | [
"19460342"
] | [
"Cep76, a centrosomal protein that specifically restrains centriole reduplication."
] | [
2009
] | 1 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
1262
] | 1 | [
"Danio rerio",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
2,
3,
1,
4
] | 4 | true | Domain | CEP76, N-terminal | CEP76, N-terminal | CEP76_N | 4 |
IPR056290 | 56,290 | CEP76/DRC7, peptidase-like domain | CEPT76/DRC7_peptidase-like_dom | Domain | 5,827 | false | false | This entry represents a domain found in the middle of centrosomal protein of 76 kDa, a protein involved in regulation of centriole duplication to limit centriole duplication to once per cell cycle by preventing centriole reduplication [ ]. This domain is also found towards the C-terminal of C2D2A/B, and in dynein regul... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF24656"
] | [
"CEPT76_peptidase"
] | [
5827
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-HSA-2565942",
"R-HSA-380259",
"R-HSA-380270",
"R-HSA-380284",
"R-HSA-380320",
"R-HSA-5620912",
"R-HSA-8854518",
"R-MMU-2565942",
"R-MMU-380259",
"R-MMU-380270",
"R-MMU-380284",
"R-MMU-380320",
"R-MMU-5620912",
"R-MMU-8854518",
"R-XTR-2565942",
"R-XTR-380259",
"R-XTR-380270",
"R-... | [
"REACTOME:R-HSA-2565942",
"REACTOME:R-HSA-380259",
"REACTOME:R-HSA-380270",
"REACTOME:R-HSA-380284",
"REACTOME:R-HSA-380320",
"REACTOME:R-HSA-5620912",
"REACTOME:R-HSA-8854518",
"REACTOME:R-MMU-2565942",
"REACTOME:R-MMU-380259",
"REACTOME:R-MMU-380270",
"REACTOME:R-MMU-380284",
"REACTOME:R-MMU... | 20 | [
"8glv",
"8j07",
"8th8",
"8tid",
"9fqr"
] | 5 | [
"PUB00069719",
"PUB00069721",
"PUB00156015"
] | [
"19460342",
"18513680",
"31961863"
] | [
"Cep76, a centrosomal protein that specifically restrains centriole reduplication.",
"Identification of CC2D2A as a Meckel syndrome gene adds an important piece to the ciliopathy puzzle.",
"Nexin-Dynein regulatory complex component DRC7 but not FBXL13 is required for sperm flagellum formation and male fertility... | [
2009,
2008,
2020
] | 3 | [] | [] | 0 | 0 | null | [
"Eukaryota",
"Nanobdellati",
"Pseudomonadati",
"ecological metagenomes"
] | [
5738,
4,
72,
13
] | 4 | [
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
1,
19,
1,
11,
6,
15
] | 6 | true | Domain | CEP76/DRC7, peptidase-like domain | CEP76/DRC7, peptidase-like domain | CEPT76/DRC7_peptidase-like_dom | 2 |
IPR056291 | 56,291 | Dynein regulatory complex subunit 7, MORN domain | MORN_DRC7 | Domain | 1,950 | false | false | Dynein regulatory complex subunit 7 (DRC7) is a component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes [ ]. In humans, defective ciliary motility can le... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF24667"
] | [
"MORN_DRC7"
] | [
1950
] | 1 | [] | [] | [] | 0 | [
"8glv",
"8j07",
"8th8",
"8tid",
"9e5c",
"9fqr"
] | 6 | [
"PUB00152767"
] | [
"37258679"
] | [
"Axonemal structures reveal mechanoregulatory and disease mechanisms."
] | [
2023
] | 1 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
1950
] | 1 | [
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
2,
1,
2,
1,
2
] | 5 | true | Domain | Dynein regulatory complex subunit 7, MORN domain | Dynein regulatory complex subunit 7, MORN domain | MORN_DRC7 | 5 |
IPR056292 | 56,292 | Dynein regulatory complex subunit 7, C-terminal | DRC7_C | Domain | 1,504 | false | false | Dynein regulatory complex subunit 7 (DRC7) is a component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes [ ]. In humans, defective ciliary motility can le... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF24671"
] | [
"DRC7_C"
] | [
1504
] | 1 | [] | [] | [] | 0 | [
"8glv",
"8j07",
"8th8",
"8tid",
"9e5c",
"9fqr"
] | 6 | [
"PUB00152767"
] | [
"37258679"
] | [
"Axonemal structures reveal mechanoregulatory and disease mechanisms."
] | [
2023
] | 1 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
1504
] | 1 | [
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
2,
1,
2,
1,
2
] | 5 | true | Domain | Dynein regulatory complex subunit 7, C-terminal | Dynein regulatory complex subunit 7, C-terminal | DRC7_C | 4 |
IPR056293 | 56,293 | CERLI1-like, PH domain | PH_CERLI1 | Domain | 198 | false | false | This entry represents a PH domain that is found in the Rhoptry Surface Protein CERLI1 family. The Rhoptry Surface Protein CERLI1 family is essential for merozoite invasion of host cells, a critical step in the life cycle of the parasite Plasmodium falciparum. Members of the family control rhoptry secretion, which is pi... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23634"
] | [
"PH_CERLI1"
] | [
198
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00156016",
"PUB00156017"
] | [
"31492901",
"32179747"
] | [
"A lipid-binding protein mediates rhoptry discharge and invasion in Plasmodium falciparum and Toxoplasma gondii parasites.",
"PfCERLI1 is a conserved rhoptry associated protein essential for Plasmodium falciparum merozoite invasion of erythrocytes."
] | [
2019,
2020
] | 2 | [] | [] | 0 | 0 | null | [
"Alveolata"
] | [
198
] | 1 | [] | [] | 0 | true | Domain | CERLI1-like, PH domain | CERLI1-like, PH domain | PH_CERLI1 | 9 |
IPR056294 | 56,294 | CFAP184, CAP-like domain | CAP-like_CFAP184 | Domain | 19 | false | false | This entry represents a domain whose function is unknown found in Cilia- and flagella-associated protein 184 (also known as CCDC96, ) from Tetrahymena thermophila and similar sequences. CFAP184 forms a complex with CFAP263, and acts as a regulator of ciliary beating that connects radial spoke 3 (RS3) to the inner dynei... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23448"
] | [
"CAP-like_CFAP184"
] | [
19
] | 1 | [] | [] | [] | 0 | [
"8tek",
"8th8",
"8tid"
] | 3 | [
"PUB00153410"
] | [
"33661892"
] | [
"Ccdc113/Ccdc96 complex, a novel regulator of ciliary beating that connects radial spoke 3 to dynein g and the nexin link."
] | [
2021
] | 1 | [] | [] | 0 | 0 | null | [
"Ciliophora"
] | [
19
] | 1 | [] | [] | 0 | true | Domain | CFAP184, CAP-like domain | CFAP184, CAP-like domain | CAP-like_CFAP184 | 7 |
IPR056295 | 56,295 | CFAP184, CBM-like domain | CBM-like_CFAP184 | Domain | 20 | false | false | This entry represents a domain of unknown function found in Cilia- and flagella-associated protein 184 (also known as CCDC96, ) from Tetrahymena thermophila and similar sequences. CFAP184 forms a complex with CFAP263, and acts as a regulator of ciliary beating that connects radial spoke 3 (RS3) to the inner dynein arm ... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23449"
] | [
"CBM-like_CFAP184"
] | [
20
] | 1 | [] | [] | [] | 0 | [
"8tek",
"8th8",
"8tid"
] | 3 | [
"PUB00153410"
] | [
"33661892"
] | [
"Ccdc113/Ccdc96 complex, a novel regulator of ciliary beating that connects radial spoke 3 to dynein g and the nexin link."
] | [
2021
] | 1 | [] | [] | 0 | 0 | null | [
"Ciliophora"
] | [
20
] | 1 | [] | [] | 0 | true | Domain | CFAP184, CBM-like domain | CFAP184, CBM-like domain | CBM-like_CFAP184 | 9 |
IPR056296 | 56,296 | Cfap43, N-terminal domain | Cfap43_N | Domain | 183 | false | false | This entry represents the first β-propeller domain found at the N-terminal of Cfap43 from Trypanosoma sp, and similar sequences from lower eukaryotes, according to structural prediction. These proteins are essential for flagellar function and, consequently, cell proliferation in T. brucei [ ]. Cfap43 is an evolutionari... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23185"
] | [
"CFAP43_N"
] | [
183
] | 1 | [] | [] | [] | 0 | [
"9e5c"
] | 1 | [
"PUB00089986",
"PUB00160595",
"PUB00160596"
] | [
"29449551",
"28552195",
"31884020"
] | [
"Mutations in CFAP43 and CFAP44 cause male infertility and flagellum defects in Trypanosoma and human.",
"Biallelic Mutations in CFAP43 and CFAP44 Cause Male Infertility with Multiple Morphological Abnormalities of the Sperm Flagella.",
"CFAP43 modulates ciliary beating in mouse and Xenopus."
] | [
2018,
2017,
2020
] | 3 | [] | [] | 0 | 0 | null | [
"Eukaryota",
"Thermoflexibacter ruber"
] | [
182,
1
] | 2 | [
"Danio rerio"
] | [
1
] | 1 | true | Domain | Cfap43, N-terminal domain | Cfap43, N-terminal domain | Cfap43_N | 3 |
IPR056297 | 56,297 | Cfap43, second beta-propeller domain | Beta-prop_Cfap43_2nd | Domain | 65 | false | false | This entry represents the second β-propeller domain found in Cfap43 protein from Trypanosoma brucei brucei and related sequences mainly from Kinetoplastids. This protein is located between the doublet microtubules 5 and 6 and associated with the axoneme along the paraflagellar rod [ ]. Cfap43 is an evolutionarily conse... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23184"
] | [
"WD40_CFAP43"
] | [
65
] | 1 | [] | [] | [] | 0 | [
"9e5c"
] | 1 | [
"PUB00089986",
"PUB00160595",
"PUB00160596"
] | [
"29449551",
"28552195",
"31884020"
] | [
"Mutations in CFAP43 and CFAP44 cause male infertility and flagellum defects in Trypanosoma and human.",
"Biallelic Mutations in CFAP43 and CFAP44 Cause Male Infertility with Multiple Morphological Abnormalities of the Sperm Flagella.",
"CFAP43 modulates ciliary beating in mouse and Xenopus."
] | [
2018,
2017,
2020
] | 3 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
65
] | 1 | [] | [] | 0 | true | Domain | Cfap43, second beta-propeller domain | Cfap43, second beta-propeller domain | Beta-prop_Cfap43_2nd | 4 |
IPR056298 | 56,298 | AlkZ related | AlkZ-rel | Family | 733 | false | false | This entry represents uncharacterised bacterial proteins that have similarity to AlkZ-like proteins . AlkZ adopts a unique fold in which three tandem winged helix-turn-helix (HTH) motifs scaffold a positively charged concave surface shaped for binding to duplex DNA [ ]. In contrast, the members of this family contain t... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF24741"
] | [
"AlkZ-rel"
] | [
733
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00100682"
] | [
"28396405"
] | [
"Structure of a DNA glycosylase that unhooks interstrand cross-links."
] | [
2017
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria",
"metagenomes"
] | [
719,
14
] | 2 | [] | [] | 0 | true | Family | AlkZ related | AlkZ related | AlkZ-rel | 4 |
IPR056299 | 56,299 | CFAP61, dimerisation domain | CFAP61_dimer | Domain | 1,664 | false | false | This entry represents a domain found at the C-terminal of the FAD reductase domain of cilia and flagella associated protein 61 (CFAP61), which may be involved in dimerisation. CFAP61 is located at the midpiece of the sperm, where it apparently functions in flagellum formation [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23150"
] | [
"CFAP61_dimer"
] | [
1664
] | 1 | [] | [] | [] | 0 | [
"8glv",
"8j07",
"9d2f",
"9fqr"
] | 4 | [
"PUB00155586"
] | [
"36659204"
] | [
"Absence of murine CFAP61 causes male infertility due to multiple morphological abnormalities of the flagella."
] | [
2020
] | 1 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
1664
] | 1 | [
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
6,
4,
2,
2,
5
] | 5 | true | Domain | CFAP61, dimerisation domain | CFAP61, dimerisation domain | CFAP61_dimer | 5 |
IPR056300 | 56,300 | Alpha-amylase SusG-like, C-terminal domain | SusG-like_C | Domain | 6,364 | false | false | This entry represents the C-terminal domain found in the starch utilisation system protein G (SusG) from bacteria. SusG forms part of the SusDEFG lipoprotein complex tethered to the outer surface of the cell and is involved in starch hydrolysis and subsequent utilisation of the resulting sugars as an energy source [ ].... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23915"
] | [
"SusG_C"
] | [
6364
] | 1 | [
"EC"
] | [
"3.2.1"
] | [
"EC:3.2.1"
] | 1 | [
"1m53",
"1uok",
"3gbd",
"3gbe",
"3k8k",
"3k8l",
"3k8m",
"3wy1",
"3wy2",
"3wy3",
"3wy4",
"4aie",
"4how",
"4hox",
"4hoz",
"4hp5",
"4hph",
"5brp",
"5brq",
"6bs6",
"7jjt",
"9fz0",
"9fz2",
"9u7v"
] | 24 | [
"PUB00075681",
"PUB00129986"
] | [
"10986238",
"10572122"
] | [
"Characterization of four outer membrane proteins involved in binding starch to the cell surface of Bacteroides thetaiotaomicron.",
"Physiological characterization of SusG, an outer membrane protein essential for starch utilization by Bacteroides thetaiotaomicron."
] | [
2000,
1999
] | 2 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Halobacteriales",
"metagenomes"
] | [
6144,
182,
12,
26
] | 4 | [] | [] | 0 | true | Domain | Alpha-amylase SusG-like, C-terminal domain | Alpha-amylase SusG-like, C-terminal domain | SusG-like_C | 4 |
IPR056302 | 56,302 | ATP-dependent helicase CHD1-2/hrp3, HTH domain | CHD1-2/Hrp3_HTH | Domain | 7,102 | false | false | This domain is found in ATP-dependent helicase hrp3 (Hrp3) from Schizosaccharomyces pombe and Chromodomain-helicase-DNA-binding protein 1 and 2 (CHD1-2) from eukaryotes. Hrp3 is involved in heterochromatin silencing. It is predicted to adopt an HTH structure and is often found C-terminal to . | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23588"
] | [
"HTH_CHD1_Hrp3"
] | [
7102
] | 1 | [
"EC",
"METACYC",
"REACTOME"
] | [
"3.6.4.-",
"PWY-7250",
"R-HSA-9018519"
] | [
"EC:3.6.4.-",
"METACYC:PWY-7250",
"REACTOME:R-HSA-9018519"
] | 3 | [
"2xb0",
"3ted",
"4b4c",
"5j70",
"5o9g",
"6ftx",
"6g0l",
"7nkx",
"7tn2",
"9ear",
"9gd1",
"9gd2",
"9gd3",
"9n6k",
"9nh8"
] | 15 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
7102
] | 1 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Saccharomyces cerevisiae (strai... | [
5,
1,
10,
6,
5,
6,
1,
5,
11,
1,
2,
86
] | 12 | true | Domain | ATP-dependent helicase CHD1-2/hrp3, HTH domain | ATP-dependent helicase CHD1-2/hrp3, HTH domain | CHD1-2/Hrp3_HTH | 2 |
IPR056303 | 56,303 | AMIN-like domain | AMIN-like | Domain | 2,853 | false | false | This domain is found in a group of extracellular likely lipoproteins that adopt a structure similar to the AMIN domain. However, there are some topological differences between the two domains. Members of this entry are predominantly found in actinomycetes. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF24837"
] | [
"AMIN-like"
] | [
2853
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Thermococcus",
"metagenomes"
] | [
2826,
5,
22
] | 3 | [] | [] | 0 | true | Domain | AMIN-like domain | AMIN-like domain | AMIN-like | 4 |
IPR056304 | 56,304 | Lipase-like, C-terminal domain | Lip-like_C | Domain | 2,679 | false | false | This domain is found in lipases from Staphylococcus hyicus (Lip) and related proteins. Lip has a broad substrate specificity hydrolysing a variety of triglycerides and phosphatidylcholines [ , ]. This domain is also found in uncharacterised sequences from plants, fungi and a few sequences from Platyhelminthes. It adopt... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF24708"
] | [
"Lip_C"
] | [
2679
] | 1 | [
"EC",
"METACYC"
] | [
"3.1.1.3",
"PWY-6857"
] | [
"EC:3.1.1.3",
"METACYC:PWY-6857"
] | 2 | [
"1ji3",
"1ku0",
"2dsn",
"2hih",
"2w22",
"2z5g",
"3auk",
"3umj",
"4fdm",
"4fkb",
"4fmp",
"4x6u",
"4x71",
"4x7b",
"4x85",
"5ah0",
"5ah1",
"5ce5",
"5xpx",
"6a12",
"6fz1",
"6fz7",
"6fz8",
"6fz9",
"6fza",
"6fzc",
"6fzd",
"6ksi",
"6ksl",
"6ksm",
"6s3g",
"6s3j"... | 42 | [
"PUB00047605",
"PUB00156018"
] | [
"17582438",
"2611229"
] | [
"Structural basis of phospholipase activity of Staphylococcus hyicus lipase.",
"Purification and substrate specificity of Staphylococcus hyicus lipase."
] | [
2007,
1989
] | 2 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Methanobacteriota",
"Yasminevirus sp. GU-2018",
"metagenomes"
] | [
1000,
1643,
2,
2,
32
] | 5 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
12,
2,
24
] | 3 | true | Domain | Lipase-like, C-terminal domain | Lipase-like, C-terminal domain | Lip-like_C | 1 |
IPR056305 | 56,305 | CFAP65, tenth Ig-like domain | Ig_CFAP65_10th | Domain | 1,734 | false | false | This entry represents the tenth Ig-like domain located towards the C-terminal in human Cilia- and flagella-associated protein 65 (CFAP65) and similar animal sequences. Cilia-Flagella-Associated Protein 65 (CFAP65) is involved in the structural and functional integrity of cilia and flagella. This protein is implicated i... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF24291"
] | [
"Ig_CFAP65"
] | [
1734
] | 1 | [] | [] | [] | 0 | [
"7n61",
"7som",
"9ijj"
] | 3 | [
"PUB00160504"
] | [
"22761584"
] | [
"The Rose-comb mutation in chickens constitutes a structural rearrangement causing both altered comb morphology and defective sperm motility."
] | [
2012
] | 1 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
1734
] | 1 | [
"Danio rerio",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
6,
1,
2,
2
] | 4 | true | Domain | CFAP65, tenth Ig-like domain | CFAP65, tenth Ig-like domain | Ig_CFAP65_10th | 5 |
IPR056306 | 56,306 | CFAP74, second Ig-like domain | Ig-CFAP74_2nd | Domain | 997 | false | false | This entry represents the second Ig-like domain of CFAP74, a protein that is part of the central apparatus of the cilium axoneme and may play a role in cilium movement. It may play an important role in sperm architecture and function [ ]. Members of this entry are specific to animals. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF24770"
] | [
"Ig-CFAP74_2"
] | [
997
] | 1 | [] | [] | [] | 0 | [
"9ijj"
] | 1 | [
"PUB00155666"
] | [
"32555313"
] | [
"Biallelic mutations of CFAP74 may cause human primary ciliary dyskinesia and MMAF phenotype."
] | [
2020
] | 1 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
997
] | 1 | [
"Danio rerio",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
2,
2,
3,
5
] | 4 | true | Domain | CFAP74, second Ig-like domain | CFAP74, second Ig-like domain | Ig-CFAP74_2nd | 2 |
IPR056307 | 56,307 | CFAP74, third Ig-like domain | Ig-CFAP74_3rd | Domain | 1,029 | false | false | This entry represents the third Ig-like domain of CFAP74, a protein that is part of the central apparatus of the cilium axoneme and may play a role in cilium movement. It may play an important role in sperm architecture and function [ ]. Members of this entry are found in eukaryotes. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF24778"
] | [
"Ig-CFAP74_3rd"
] | [
1029
] | 1 | [] | [] | [] | 0 | [
"7n6g",
"7sqc",
"9ijj"
] | 3 | [
"PUB00155666"
] | [
"32555313"
] | [
"Biallelic mutations of CFAP74 may cause human primary ciliary dyskinesia and MMAF phenotype."
] | [
2020
] | 1 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
1029
] | 1 | [
"Danio rerio",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
2,
2,
3,
5
] | 4 | true | Domain | CFAP74, third Ig-like domain | CFAP74, third Ig-like domain | Ig-CFAP74_3rd | 2 |
IPR056309 | 56,309 | CGL160/ATPI domain | CGL160/ATPI_dom | Domain | 1,362 | false | false | This domain is found in Protein CONSERVED ONLY IN THE GREEN LINEAGE 160 from Arabidopsis thaliana (CGL160), ATP synthase protein I (ATPI) from cyanobacteria and similar proteins. CGL160 facilitates the assembly of the membrane proton channel of the chloroplastic F-type ATPase [ ]. ATPI may guide the assembly of the mem... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF24763"
] | [
"CGL160_C"
] | [
1362
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00155587"
] | [
"24664203"
] | [
"The Arabidopsis protein CONSERVED ONLY IN THE GREEN LINEAGE160 promotes the assembly of the membranous part of the chloroplast ATP synthase."
] | [
2014
] | 1 | [] | [] | 0 | 0 | null | [
"Cyanobacteriota",
"Eukaryota",
"Phycodnaviridae",
"viral metagenome"
] | [
336,
1020,
5,
1
] | 4 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
3,
5,
9
] | 3 | true | Domain | CGL160/ATPI domain | CGL160/ATPI domain | CGL160/ATPI_dom | 6 |
IPR056310 | 56,310 | CFAP74, fourth Ig-like domain | Ig-CFAP74_4th | Domain | 1,146 | false | false | This entry represents the fourth Ig-like domain of CFAP74, a protein that is part of the central apparatus of the cilium axoneme and may play a role in cilium movement. It may play an important role in sperm architecture and function [ ]. Members of this entry are found in eukaryotes. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF24798"
] | [
"Ig-CFAP74_4th"
] | [
1146
] | 1 | [] | [] | [] | 0 | [
"7n6g",
"7sqc",
"9ijj"
] | 3 | [
"PUB00155666"
] | [
"32555313"
] | [
"Biallelic mutations of CFAP74 may cause human primary ciliary dyskinesia and MMAF phenotype."
] | [
2020
] | 1 | [] | [] | 0 | 0 | null | [
"Eukaryota",
"Flavobacterium salmonis"
] | [
1145,
1
] | 2 | [
"Danio rerio",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
2,
2,
3,
4
] | 4 | true | Domain | CFAP74, fourth Ig-like domain | CFAP74, fourth Ig-like domain | Ig-CFAP74_4th | 2 |
IPR056311 | 56,311 | TMEM131, second Ig-like domain | TMEM131_Ig_2 | Domain | 2,128 | false | false | This entry represents the second Ig-like domain from TMEM131. TMEM131 is a collagen binding transmembrane protein involved in collagen secretion by recruiting the ER-to-Golgi transport complex TRAPPIII [ ]. Human TMEM131 is predicted to contain eight Ig-like domains. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF24495"
] | [
"Ig_TMEM131_2"
] | [
2128
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00155677"
] | [
"32095531"
] | [
"Broadly conserved roles of TMEM131 family proteins in intracellular collagen assembly and secretory cargo trafficking."
] | [
2020
] | 1 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
2128
] | 1 | [
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
1,
3,
1,
4,
1,
6
] | 6 | true | Domain | TMEM131, second Ig-like domain | TMEM131, second Ig-like domain | TMEM131_Ig_2 | 3 |
IPR056312 | 56,312 | Antitoxin Xre/MbcA/ParS-like, middle domain | Xre-MbcA-ParS_M | Domain | 230 | false | false | This entry represents a small domain found in the middle region of a group of uncharacterised bacterial sequences related to the antitoxin components of a type II toxin-antitoxin (TA) system Xre/MbcA/ParS. This domain may consist of four β-sheets and two short α-helices, which is followed by a toxin-binding domain ( ). | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23125"
] | [
"Xre-MbcA-ParS_M"
] | [
230
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria"
] | [
230
] | 1 | [] | [] | 0 | true | Domain | Antitoxin Xre/MbcA/ParS-like, middle domain | Antitoxin Xre/MbcA/ParS-like, middle domain | Xre-MbcA-ParS_M | 1 |
IPR056313 | 56,313 | Antitoxin Xre/MbcA/ParS-like, N-terminal | Xre_MbcA_ParS-like_N | Domain | 97 | false | false | This entry represents the N-terminal domain of a group of bacterial sequences related to the antitoxin components of a type II toxin-antitoxin (TA) system Xre/MbcA/ParS. This domain may adopt an α-helical fold. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23124"
] | [
"Xre_MbcA_ParS-like_N"
] | [
97
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Alphaproteobacteria"
] | [
97
] | 1 | [] | [] | 0 | true | Domain | Antitoxin Xre/MbcA/ParS-like, N-terminal | Antitoxin Xre/MbcA/ParS-like, N-terminal | Xre_MbcA_ParS-like_N | 2 |
IPR056315 | 56,315 | SmORF-like domain, apicomplexa | SmORF-like_dom_apicomplexa | Domain | 55 | false | false | This domain is found in a group of uncharacterised small proteins from apicomplexa, including SmORF ( ) from the parasite Babesia bovis, which is encoded by an small open reading frame (smORF) [ ]. This domain, predicted to adopt an α-helical structure, is found twice in some longer members. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23503"
] | [
"Microp_apicomplexa_5"
] | [
55
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00155743"
] | [
"33294524"
] | [
"Transcriptome dataset of <i>Babesia bovis</i> life stages within vertebrate and invertebrate hosts."
] | [
2020
] | 1 | [] | [] | 0 | 0 | null | [
"Babesia bovis"
] | [
55
] | 1 | [] | [] | 0 | true | Domain | SmORF-like domain, apicomplexa | SmORF-like domain, apicomplexa | SmORF-like_dom_apicomplexa | 1 |
IPR056316 | 56,316 | Microprotein, apicomplexa 2 | Microp_apicomplexa_2 | Family | 13 | false | false | This protein family includes uncharacterised microproteins encoded by small open reading frames (smORFs) from apicomplexa, including from the parasite Babesia bovis [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23483"
] | [
"Microp_apicomplexa_2"
] | [
13
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00155743"
] | [
"33294524"
] | [
"Transcriptome dataset of <i>Babesia bovis</i> life stages within vertebrate and invertebrate hosts."
] | [
2020
] | 1 | [] | [] | 0 | 0 | null | [
"Piroplasmida"
] | [
13
] | 1 | [] | [] | 0 | true | Family | Microprotein, apicomplexa 2 | Microprotein, apicomplexa 2 | Microp_apicomplexa_2 | 1 |
IPR056317 | 56,317 | Microprotein, apicomplexa | Microp_apicomplexa | Family | 12 | false | false | This protein family includes uncharacterised microproteins encoded by small open reading frames (smORFs) from apicomplexa, including from the parasite Babesia bovis [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23479"
] | [
"Microp_apicomplexa"
] | [
12
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00155743"
] | [
"33294524"
] | [
"Transcriptome dataset of <i>Babesia bovis</i> life stages within vertebrate and invertebrate hosts."
] | [
2020
] | 1 | [] | [] | 0 | 0 | null | [
"Babesia bovis"
] | [
12
] | 1 | [] | [] | 0 | true | Family | Microprotein, apicomplexa | Microprotein, apicomplexa | Microp_apicomplexa | 2 |
IPR056319 | 56,319 | NOMO, seventh transthyretin-like domain | NOMO_7th | Domain | 2,966 | false | false | This entry represents a domain centrally located in BOS complex subunit NOMO1-3 from vertebrates. This domain is also found in the homologue Nicotinic receptor-associated protein 4 from Caenorhabditis elegans [ ]. NOMO family of proteins includes NOMO1, NOMO2, NOMO3. These proteins are components of the multi-pass tran... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23141"
] | [
"Ig_NOMO"
] | [
2966
] | 1 | [] | [] | [] | 0 | [
"9c7v"
] | 1 | [
"PUB00097241",
"PUB00103609",
"PUB00103689",
"PUB00156037"
] | [
"32820719",
"36261522",
"34224731",
"19609303"
] | [
"An ER translocon for multi-pass membrane protein biogenesis.",
"Substrate-driven assembly of a translocon for multipass membrane proteins.",
"Nodal modulator (NOMO) is required to sustain endoplasmic reticulum morphology.",
"An ER-resident membrane protein complex regulates nicotinic acetylcholine receptor s... | [
2020,
2022,
2021,
2009
] | 4 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
2966
] | 1 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Zea mays"
] | [
7,
1,
1,
4,
12,
1,
1,
3,
13
] | 9 | true | Domain | NOMO, seventh transthyretin-like domain | NOMO, seventh transthyretin-like domain | NOMO_7th | 3 |
IPR056320 | 56,320 | Microprotein, apicomplexa 4 | Microp_apicomplexa_4 | Family | 9 | false | false | This protein family includes uncharacterised microproteins encoded by small open reading frames (smORFs) from apicomplexa, including from the parasite Babesia bovis [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23501"
] | [
"Microp_apicomplexa_4"
] | [
9
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00155743"
] | [
"33294524"
] | [
"Transcriptome dataset of <i>Babesia bovis</i> life stages within vertebrate and invertebrate hosts."
] | [
2020
] | 1 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
9
] | 1 | [] | [] | 0 | true | Family | Microprotein, apicomplexa 4 | Microprotein, apicomplexa 4 | Microp_apicomplexa_4 | 1 |
IPR056321 | 56,321 | Microprotein domain, apicomplexa | Microp_dom_apicomplexa | Domain | 8 | false | false | This domain covers the whole length of uncharacterised microproteins encoded by small open reading frames (smORFs) from apicomplexa, including from the parasite Babesia bovis [ ], and is found at the N-terminal end of longer uncharacterised proteins from related species. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23510"
] | [
"Microp_apicomplexa_6"
] | [
8
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00155743"
] | [
"33294524"
] | [
"Transcriptome dataset of <i>Babesia bovis</i> life stages within vertebrate and invertebrate hosts."
] | [
2020
] | 1 | [] | [] | 0 | 0 | null | [
"Babesia"
] | [
8
] | 1 | [] | [] | 0 | true | Domain | Microprotein domain, apicomplexa | Microprotein domain, apicomplexa | Microp_dom_apicomplexa | 4 |
IPR056322 | 56,322 | Microprotein, apicomplexa 21 | Microp_apicomplexa_21 | Family | 94 | false | false | This protein family includes uncharacterised microproteins encoded by small open reading frames (smORFs) from apicomplexa, including from the parasite Babesia bovis [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23535"
] | [
"Microp_apicomplexa_21"
] | [
94
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00155743"
] | [
"33294524"
] | [
"Transcriptome dataset of <i>Babesia bovis</i> life stages within vertebrate and invertebrate hosts."
] | [
2020
] | 1 | [] | [] | 0 | 0 | null | [
"Alveolata"
] | [
94
] | 1 | [] | [] | 0 | true | Family | Microprotein, apicomplexa 21 | Microprotein, apicomplexa 21 | Microp_apicomplexa_21 | 6 |
IPR056323 | 56,323 | Microprotein domain, apicomplexa 2 | Microp_dom_apicomplexa_2 | Domain | 4 | false | false | This domain covers the whole length of uncharacterised microproteins encoded by small open reading frames (smORFs) from apicomplexa, including from the parasite Babesia bovis [ ], and is found centrally located in longer uncharacterised proteins from related species. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23534"
] | [
"Microp_apicomplexa_20"
] | [
4
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00155743"
] | [
"33294524"
] | [
"Transcriptome dataset of <i>Babesia bovis</i> life stages within vertebrate and invertebrate hosts."
] | [
2020
] | 1 | [] | [] | 0 | 0 | null | [
"Babesia bovis"
] | [
4
] | 1 | [] | [] | 0 | true | Domain | Microprotein domain, apicomplexa 2 | Microprotein domain, apicomplexa 2 | Microp_dom_apicomplexa_2 | 1 |
IPR056324 | 56,324 | Microprotein domain, apicomplexa 19 | Microp_apicomplexa_19 | Domain | 93 | false | false | This domain is found in uncharacterised microproteins encoded by small open reading frames (smORFs) from apicomplexa, including from the parasite Babesia bovis [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23533"
] | [
"Microp_apicomplexa_19"
] | [
93
] | 1 | [] | [] | [] | 0 | [
"6tmg",
"6tmk",
"6tml"
] | 3 | [
"PUB00155743"
] | [
"33294524"
] | [
"Transcriptome dataset of <i>Babesia bovis</i> life stages within vertebrate and invertebrate hosts."
] | [
2020
] | 1 | [] | [] | 0 | 0 | null | [
"Apicomplexa"
] | [
93
] | 1 | [] | [] | 0 | true | Domain | Microprotein domain, apicomplexa 19 | Microprotein domain, apicomplexa 19 | Microp_apicomplexa_19 | 9 |
IPR056326 | 56,326 | ISD11 | ISD11 | Family | 124 | false | false | This entry represents ISD11 protein and related proteins including from the parasite Babesia bovis [ ]. Protein Isd11 from P. falciparum participates in iron-sulfur cluster formation pathway for iron-sulfur (Fe-S) cluster biogenesis [ ]. It enhances cysteine desulfurase activity of IscS [ ]. In T. hominis, this protein... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23511"
] | [
"ISD11"
] | [
124
] | 1 | [
"REACTOME"
] | [
"R-PFA-1362409"
] | [
"REACTOME:R-PFA-1362409"
] | 1 | [] | 0 | [
"PUB00155743",
"PUB00161577",
"PUB00161578"
] | [
"33294524",
"18311129",
"34032321"
] | [
"Transcriptome dataset of <i>Babesia bovis</i> life stages within vertebrate and invertebrate hosts.",
"Localization and functionality of microsporidian iron-sulphur cluster assembly proteins.",
"[Fe-S] biogenesis and unusual assembly of the ISC scaffold complex in the Plasmodium falciparum mitochondrion."
] | [
2020,
2008,
2021
] | 3 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
124
] | 1 | [] | [] | 0 | true | Family | ISD11 | ISD11 | ISD11 | 8 |
IPR056327 | 56,327 | ARMC9, CTLH-like domain | ARMC9_CTLH-like_dom | Domain | 4,752 | false | false | This entry represents a domain that is found C-terminal to LisH motif in human LisH domain-containing protein ARMC9 and related proteins. Armc9 is involved in ciliogenesis and is required for appropriate acetylation and polyglutamylation of ciliary microtubules, and regulation of cilium length [ ]. This domain is dista... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23138"
] | [
"CTLH_Armc9"
] | [
4752
] | 1 | [
"REACTOME"
] | [
"R-HSA-9013148"
] | [
"REACTOME:R-HSA-9013148"
] | 1 | [] | 0 | [
"PUB00090016",
"PUB00151677"
] | [
"26783301",
"32453716"
] | [
"Negative regulation of phosphatidylinositol 3-phosphate levels in early-to-late endosome conversion.",
"Dysfunction of the ciliary ARMC9/TOGARAM1 protein module causes Joubert syndrome."
] | [
2016,
2020
] | 2 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
4752
] | 1 | [
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus",
"Zea mays"
] | [
1,
7,
1,
22,
7,
13,
4
] | 7 | true | Domain | ARMC9, CTLH-like domain | ARMC9, CTLH-like domain | ARMC9_CTLH-like_dom | 5 |
IPR056328 | 56,328 | ATP-dependent RNA helicase DHX29, DSRM-like domain | DSRM_DHX29 | Domain | 3,224 | false | false | This is a presumed domain found near the middle of ATP-dependent RNA helicase DHX29 from human and at the N-terminal of the putative ATP-dependent RNA helicase YLR419W from yeast, which has been identified as the homologue of the translation initiation factor DHX29 from human [ ]. DHX29 is a DExH-box protein involved i... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF24385"
] | [
"DSRM_DHX29"
] | [
3224
] | 1 | [
"EC"
] | [
"3.6.4.13"
] | [
"EC:3.6.4.13"
] | 1 | [
"9cpa"
] | 1 | [
"PUB00084241",
"PUB00155607"
] | [
"23706745",
"38585201"
] | [
"Structure of the mammalian ribosomal 43S preinitiation complex bound to the scanning factor DHX29.",
"YLR419W is the homolog of the mammalian translation initiation factor <i>DHX29</i>."
] | [
2013,
2024
] | 2 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
3224
] | 1 | [
"Danio rerio",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)",
"Schizosaccharomyces pombe (strain 972 / ATCC 24843)"
] | [
1,
1,
1,
1,
3,
4,
1,
1
] | 8 | true | Domain | ATP-dependent RNA helicase DHX29, DSRM-like domain | ATP-dependent RNA helicase DHX29, DSRM-like domain | DSRM_DHX29 | 9 |
IPR056330 | 56,330 | ATP-dependent rRNA helicase SPB4-like, C-terminal tail | CTT_SPB4 | Domain | 1,990 | false | false | This domain is found at the C-terminal end of ATP-dependent rRNA helicase SPB4 from Saccharomyces cerevisiae and similar sequences mainly from fungi and some animal species. SPB4 is involved in the biogenesis of 60S ribosomal subunits. It is is organised into four domains: dual RecA domains ( and ), a C-terminal extens... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23681"
] | [
"CTT_SPB4"
] | [
1990
] | 1 | [
"EC"
] | [
"3.6.4.13"
] | [
"EC:3.6.4.13"
] | 1 | [
"7nac",
"7nad",
"7r72",
"7r7a",
"8i9z",
"8ia0"
] | 6 | [
"PUB00153742"
] | [
"36482249"
] | [
"Sequence-specific remodeling of a topologically complex RNP substrate by Spb4."
] | [
2022
] | 1 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
1990
] | 1 | [
"Drosophila melanogaster",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)",
"Schizosaccharomyces pombe (strain 972 / ATCC 24843)"
] | [
1,
1,
1,
1
] | 4 | true | Domain | ATP-dependent rRNA helicase SPB4-like, C-terminal tail | ATP-dependent rRNA helicase SPB4-like, C-terminal tail | CTT_SPB4 | 2 |
IPR056332 | 56,332 | BBS7, beta-propeller | Beta-prop_BBS7 | Domain | 2,056 | false | false | This entry represents the BBS7 β-propeller domain. The BBS7 β-propeller interacts with the β-propeller domain of another BBSome protein, BBS1, in order to control access of the membrane-recruiting protein ARL6 [ ]. Members of this group are mainly found in animals. Bardet-Biedl syndrome 7 (BBS7) forms a part of the BBS... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23743"
] | [
"Beta-prop_BBS7"
] | [
2056
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-CEL-5620922",
"R-HSA-5620922",
"R-MMU-5620922"
] | [
"REACTOME:R-CEL-5620922",
"REACTOME:R-HSA-5620922",
"REACTOME:R-MMU-5620922"
] | 3 | [
"6vbu",
"6vbv",
"6vnw",
"6voa"
] | 4 | [
"PUB00043590",
"PUB00043591",
"PUB00043592",
"PUB00043593",
"PUB00145818",
"PUB00153354",
"PUB00153357",
"PUB00154979",
"PUB00155514",
"PUB00155515"
] | [
"18506366",
"18317593",
"18334641",
"18032602",
"16909204",
"31939736",
"32510327",
"25335890",
"23572516",
"31303482"
] | [
"Regulation of Alstrom syndrome gene expression during adipogenesis and its relationship with fat cell insulin sensitivity.",
"Leptin resistance contributes to obesity and hypertension in mouse models of Bardet-Biedl syndrome.",
"Bardet-Biedl syndrome proteins are required for the localization of G protein-coup... | [
2008,
2008,
2008,
2007,
2006,
2020,
2020,
2014,
2013,
2019
] | 10 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
2056
] | 1 | [
"Caenorhabditis elegans",
"Danio rerio",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
1,
1,
1,
7,
7
] | 5 | true | Domain | BBS7, beta-propeller | BBS7, beta-propeller | Beta-prop_BBS7 | 1 |
IPR056333 | 56,333 | BBS7, platform domain | BBS7_pf_dom | Domain | 1,749 | false | false | This entry represents the platform domain of BBS7. Members of this group are mainly found in animals. Bardet-Biedl syndrome 7 (BBS7) forms a part of the BBSome complex, which is required for ciliogenesis [ ]. BBS7 is the BBSome subunit responsible for the binding to SMO H8 [ ] and plays a role in guanylyl cyclase local... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23361"
] | [
"BBS7_pf"
] | [
1749
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-CEL-5620922",
"R-HSA-5620922",
"R-MMU-5620922"
] | [
"REACTOME:R-CEL-5620922",
"REACTOME:R-HSA-5620922",
"REACTOME:R-MMU-5620922"
] | 3 | [
"6vbu",
"6vbv",
"6vnw",
"6voa"
] | 4 | [
"PUB00043590",
"PUB00043591",
"PUB00043592",
"PUB00043593",
"PUB00060532",
"PUB00093551",
"PUB00145818",
"PUB00153354",
"PUB00153357",
"PUB00154979"
] | [
"18506366",
"18317593",
"18334641",
"18032602",
"17574030",
"22922713",
"16909204",
"31939736",
"32510327",
"25335890"
] | [
"Regulation of Alstrom syndrome gene expression during adipogenesis and its relationship with fat cell insulin sensitivity.",
"Leptin resistance contributes to obesity and hypertension in mouse models of Bardet-Biedl syndrome.",
"Bardet-Biedl syndrome proteins are required for the localization of G protein-coup... | [
2008,
2008,
2008,
2007,
2007,
2012,
2006,
2020,
2020,
2014
] | 10 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
1749
] | 1 | [
"Caenorhabditis elegans",
"Danio rerio",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
1,
1,
1,
6,
6
] | 5 | true | Domain | BBS7, platform domain | BBS7, platform domain | BBS7_pf_dom | 4 |
IPR056334 | 56,334 | BBS7, GAE domain | BBS7_GAE_dom | Domain | 1,909 | false | false | This entry represents the gamma-adaptin ear (GAE) domain of BBS7. Members of this group are mainly found in animals. Bardet-Biedl syndrome 7 (BBS7) forms a part of the BBSome complex, which is required for ciliogenesis [ ]. BBS7 is the BBSome subunit responsible for the binding to SMO H8 [ ] and plays a role in guanyly... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23360"
] | [
"BBS7_GAE"
] | [
1909
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-CEL-5620922",
"R-HSA-5620922",
"R-MMU-5620922"
] | [
"REACTOME:R-CEL-5620922",
"REACTOME:R-HSA-5620922",
"REACTOME:R-MMU-5620922"
] | 3 | [
"6vbu",
"6vbv",
"6vnw",
"6voa"
] | 4 | [
"PUB00043590",
"PUB00043591",
"PUB00043592",
"PUB00043593",
"PUB00145818",
"PUB00153354",
"PUB00153357",
"PUB00154979"
] | [
"18506366",
"18317593",
"18334641",
"18032602",
"16909204",
"31939736",
"32510327",
"25335890"
] | [
"Regulation of Alstrom syndrome gene expression during adipogenesis and its relationship with fat cell insulin sensitivity.",
"Leptin resistance contributes to obesity and hypertension in mouse models of Bardet-Biedl syndrome.",
"Bardet-Biedl syndrome proteins are required for the localization of G protein-coup... | [
2008,
2008,
2008,
2007,
2006,
2020,
2020,
2014
] | 8 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
1909
] | 1 | [
"Caenorhabditis elegans",
"Danio rerio",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
1,
1,
1,
6,
6
] | 5 | true | Domain | BBS7, GAE domain | BBS7, GAE domain | BBS7_GAE_dom | 7 |
IPR056335 | 56,335 | BBS7, helical hairpin | BBS7_hairpin | Domain | 1,646 | false | false | This entry represents a helical hairpin domain found in Bardet-Biedl syndrome 7 (BBS7) proteins from animals, including human and mouse. Bardet-Biedl syndrome 7 (BBS7) forms a part of the BBSome complex, which is required for ciliogenesis [ ]. BBS7 is the BBSome subunit responsible for the binding to SMO H8 [ ] and pla... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23349"
] | [
"BBS7_hp"
] | [
1646
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-CEL-5620922",
"R-HSA-5620922",
"R-MMU-5620922"
] | [
"REACTOME:R-CEL-5620922",
"REACTOME:R-HSA-5620922",
"REACTOME:R-MMU-5620922"
] | 3 | [
"6vbu",
"6vbv",
"6vnw",
"6voa"
] | 4 | [
"PUB00043590",
"PUB00043591",
"PUB00043592",
"PUB00043593",
"PUB00145818",
"PUB00153354",
"PUB00153357",
"PUB00154979"
] | [
"18506366",
"18317593",
"18334641",
"18032602",
"16909204",
"31939736",
"32510327",
"25335890"
] | [
"Regulation of Alstrom syndrome gene expression during adipogenesis and its relationship with fat cell insulin sensitivity.",
"Leptin resistance contributes to obesity and hypertension in mouse models of Bardet-Biedl syndrome.",
"Bardet-Biedl syndrome proteins are required for the localization of G protein-coup... | [
2008,
2008,
2008,
2007,
2006,
2020,
2020,
2014
] | 8 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
1646
] | 1 | [
"Caenorhabditis elegans",
"Danio rerio",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
1,
1,
2,
6,
6
] | 5 | true | Domain | BBS7, helical hairpin | BBS7, helical hairpin | BBS7_hairpin | 7 |
IPR056336 | 56,336 | Calcium channel YVC1-like, C-terminal transmembrane domain | YVC1_C | Domain | 24,108 | false | false | This domain is found in members of the transient receptor potential Ca2+/cation channel (TRP-CC) family. It is found in Calcium channel YVC1 from Saccharomyces cerevisiae, for example, which is a transient receptor potential (TRP) channel required for release of calcium ions from the vacuole in response to hyperosmotic... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23317"
] | [
"YVC1_C"
] | [
24108
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOM... | [
"R-BTA-114508",
"R-BTA-139853",
"R-BTA-3295583",
"R-CEL-114508",
"R-CEL-139853",
"R-CEL-3295583",
"R-CFA-3295583",
"R-DME-3295583",
"R-DME-5578775",
"R-DME-983695",
"R-HSA-114508",
"R-HSA-139853",
"R-HSA-3295583",
"R-HSA-418890",
"R-HSA-5578775",
"R-HSA-9022699",
"R-HSA-983695",
"R... | [
"REACTOME:R-BTA-114508",
"REACTOME:R-BTA-139853",
"REACTOME:R-BTA-3295583",
"REACTOME:R-CEL-114508",
"REACTOME:R-CEL-139853",
"REACTOME:R-CEL-3295583",
"REACTOME:R-CFA-3295583",
"REACTOME:R-DME-3295583",
"REACTOME:R-DME-5578775",
"REACTOME:R-DME-983695",
"REACTOME:R-HSA-114508",
"REACTOME:R-HS... | 28 | [
"3j5p",
"3j5q",
"3j5r",
"3j9j",
"5an8",
"5irx",
"5irz",
"5is0",
"5vkq",
"5yx9",
"5zbg",
"5zx5",
"6bwd",
"6bwf",
"6co7",
"6cud",
"6cv9",
"6d7l",
"6dvw",
"6dvy",
"6dvz",
"6g1k",
"6lgp",
"6mho",
"6mhs",
"6mhv",
"6mhw",
"6mhx",
"6nr3",
"6nr4",
"6o6a",
"6o6r"... | 185 | [
"PUB00155706",
"PUB00155926"
] | [
"34453887",
"31519888"
] | [
"Structure of the ancient TRPY1 channel from Saccharomyces cerevisiae reveals mechanisms of modulation by lipids and calcium.",
"Structure of the thermo-sensitive TRP channel TRP1 from the alga Chlamydomonas reinhardtii."
] | [
2022,
2019
] | 2 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
24108
] | 1 | [
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Rattus norvegicus",
"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)"
] | [
4,
24,
10,
41,
36,
5,
58,
1
] | 8 | true | Domain | Calcium channel YVC1-like, C-terminal transmembrane domain | Calcium channel YVC1-like, C-terminal transmembrane domain | YVC1_C | 6 |
IPR056337 | 56,337 | YVC1, N-terminal linker helical domain | LHD_YVC1 | Domain | 4,317 | false | false | This domain is found N-terminal in the yeast calcium channel YVC1 (also known as TRPY1) and similar fungal proteins. YVC1 is a transient receptor potential (TRP) channel that acts as a mechanosensitive osmoregulator. It is non-selective Ca2+ permeable and polymodal cation channel that function similarly to other TRP ch... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23190"
] | [
"LHD_TRPY1"
] | [
4317
] | 1 | [
"REACTOME"
] | [
"R-SCE-3295583"
] | [
"REACTOME:R-SCE-3295583"
] | 1 | [
"6whg"
] | 1 | [
"PUB00155706"
] | [
"34453887"
] | [
"Structure of the ancient TRPY1 channel from Saccharomyces cerevisiae reveals mechanisms of modulation by lipids and calcium."
] | [
2022
] | 1 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
4317
] | 1 | [
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)"
] | [
4,
1
] | 2 | true | Domain | YVC1, N-terminal linker helical domain | YVC1, N-terminal linker helical domain | LHD_YVC1 | 1 |
IPR056338 | 56,338 | Cap15-like, TM helices | Cap15-like_TM | Domain | 170 | false | false | This entry includes CD-NTase-associated protein 15 from Yersinia aleksiciae (Cap15, ), an effector protein of a CBASS antivirus system [ ]. These proteins occur in conserved genome contexts with the SMODS nucleotide synthetase [ ]. Cap15 consists of two transmembrane segments (TM) at the N-terminal, represented in this... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23471"
] | [
"Cap15_TM"
] | [
170
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00153405"
] | [
"34784509"
] | [
"Effector-mediated membrane disruption controls cell death in CBASS antiphage defense."
] | [
2021
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Methanobacteriota",
"Rhizopus delemar",
"marine sediment metagenome",
"uncultured Caudovirales phage"
] | [
163,
3,
1,
2,
1
] | 5 | [] | [] | 0 | true | Domain | Cap15-like, TM helices | Cap15-like, TM helices | Cap15-like_TM | 1 |
IPR056339 | 56,339 | Card1, CARF domain | CARF_Card1 | Domain | 440 | false | false | This is the CARF domain found at the N-terminal of a set of bacterial proteins, including Card1 (cyclic-oligoadenylate-activated single-stranded ribonuclease and single-stranded deoxyribonuclease 1) from Treponema succinifaciens ( ), a protein that is part of type III CRISPR-Cas immune response system. This protein con... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23400"
] | [
"CARF_Card1"
] | [
440
] | 1 | [] | [] | [] | 0 | [
"6wxw",
"6wxx",
"6wxy",
"6xl1",
"7bdv",
"8bao",
"8q3y",
"8q3z",
"8q40",
"8q41",
"8q42",
"8q43",
"8q44"
] | 13 | [
"PUB00153094"
] | [
"33461211"
] | [
"The Card1 nuclease provides defence during type III CRISPR immunity."
] | [
2021
] | 1 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"unclassified sequences"
] | [
9,
416,
15
] | 3 | [] | [] | 0 | true | Domain | Card1, CARF domain | Card1, CARF domain | CARF_Card1 | 7 |
IPR056340 | 56,340 | Carboxypeptidase Rv3627c-like, N-terminal domain | Rv3627c-like_N | Domain | 362 | false | false | This is the short N-terminal domain of Carboxypeptidase Rv3627c from Mycobacterium tuberculosis and similar sequences found in actinobacteria. This domain is predicted to form an α-helix. Carboxypeptidase Rv3627c cleaves terminal D-alanine from peptidoglycan in the mycobacterial cell wall. It exerts important effects o... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23714"
] | [
"Rv3627c_N"
] | [
362
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00155614",
"PUB00156020"
] | [
"36243697",
"31000162"
] | [
"Comparative genome analysis of mycobacteria focusing on tRNA and non-coding RNA.",
"Identification of a novel carboxypeptidase encoded by Rv3627c that plays a potential role in mycobacteria morphology and cell division."
] | [
2022,
2019
] | 2 | [] | [] | 0 | 0 | null | [
"Actinomycetes"
] | [
362
] | 1 | [] | [] | 0 | true | Domain | Carboxypeptidase Rv3627c-like, N-terminal domain | Carboxypeptidase Rv3627c-like, N-terminal domain | Rv3627c-like_N | 6 |
IPR056341 | 56,341 | Chp1, domain II | Chp1_domII | Domain | 2 | false | false | Chp1 is required for RNA interference-dependent heterochromatin formation in fission yeast, and it is a member of the RNA-induced transcriptional silencing (RITS) complex which maintains the heterochromatin regions, playing a role in stabilising microtubules which allows accurate chromosome segregation [ ]. This entry ... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23340"
] | [
"Chp1_domII"
] | [
2
] | 1 | [
"REACTOME"
] | [
"R-SPO-983231"
] | [
"REACTOME:R-SPO-983231"
] | 1 | [
"3tix"
] | 1 | [
"PUB00145415"
] | [
"22081013"
] | [
"The Chp1-Tas3 core is a multifunctional platform critical for gene silencing by RITS."
] | [
2011
] | 1 | [] | [] | 0 | 0 | null | [
"Schizosaccharomyces"
] | [
2
] | 1 | [
"Schizosaccharomyces pombe (strain 972 / ATCC 24843)"
] | [
1
] | 1 | true | Domain | Chp1, domain II | Chp1, domain II | Chp1_domII | 5 |
IPR056343 | 56,343 | Cilia- and flagella-associated protein 47 domain | CFAP47_dom | Domain | 1,308 | false | false | This domain is found in human Cilia- and flagella-associated protein 47 (CFAP47) and similar proteins mainly from animals. CFAP47 plays a role in flagellar formation and sperm motility [ ]. This domain is usually found associated with . | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF24529"
] | [
"CFAP47"
] | [
1308
] | 1 | [] | [] | [] | 0 | [
"7n6g",
"7sqc",
"9ijj"
] | 3 | [
"PUB00155585"
] | [
"33472045"
] | [
"Deleterious variants in X-linked CFAP47 induce asthenoteratozoospermia and primary male infertility."
] | [
2021
] | 1 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
1308
] | 1 | [
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
2,
2,
6
] | 3 | true | Domain | Cilia- and flagella-associated protein 47 domain | Cilia- and flagella-associated protein 47 domain | CFAP47_dom | 2 |
IPR056344 | 56,344 | CFAP65-like, ninth Ig-like domain | Ig_CFAP65-like_9th | Domain | 1,727 | false | false | This entry represents the ninth Ig-like domain of CFAP65 and related sequences. This domain is also found in hydrocephalus-inducing protein, which is required for ciliary motility [ ]. Cilia-Flagella-Associated Protein 65 (CFAP65) is involved in the structural and functional integrity of cilia and flagella. This protei... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF24816"
] | [
"Ig_CFAP65__9th"
] | [
1727
] | 1 | [] | [] | [] | 0 | [
"7n61",
"7som",
"9ijj"
] | 3 | [
"PUB00078384",
"PUB00155585",
"PUB00160504"
] | [
"18250199",
"33472045",
"22761584"
] | [
"Mutations in Hydin impair ciliary motility in mice.",
"Deleterious variants in X-linked CFAP47 induce asthenoteratozoospermia and primary male infertility.",
"The Rose-comb mutation in chickens constitutes a structural rearrangement causing both altered comb morphology and defective sperm motility."
] | [
2008,
2021,
2012
] | 3 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
1727
] | 1 | [
"Danio rerio",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
6,
2,
3,
5
] | 4 | true | Domain | CFAP65-like, ninth Ig-like domain | CFAP65-like, ninth Ig-like domain | Ig_CFAP65-like_9th | 5 |
IPR056345 | 56,345 | CIZ1, C2H2-type zinc finger | Znf-C2H2_CIZ1 | Domain | 2,008 | false | false | This C2H2-type zinc finger domain is found in human Cip1-interacting zinc finger protein (CIZ1), its orthologue from Drosophila Zinc finger protein on ecdysone puffs and similar animal proteins. CIZ1 may regulate the subcellular localisation of CIP/WAF1 [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23330"
] | [
"zf-C2H2_14"
] | [
2008
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00062261"
] | [
"10529385"
] | [
"Cloning and characterization of a novel p21(Cip1/Waf1)-interacting zinc finger protein, ciz1."
] | [
1999
] | 1 | [] | [] | 0 | 0 | null | [
"Bilateria"
] | [
2008
] | 1 | [
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
25,
3,
10,
8,
6
] | 5 | true | Domain | CIZ1, C2H2-type zinc finger | CIZ1, C2H2-type zinc finger | Znf-C2H2_CIZ1 | 3 |
IPR056348 | 56,348 | Microprotein, apicomplexa 9 | Microp_apicomplexa_9 | Family | 81 | false | false | This protein family includes uncharacterised microproteins encoded by small open reading frames (smORFs) from apicomplexa, including from the parasite Babesia bovis [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23513"
] | [
"Microp_apicomplexa_9"
] | [
81
] | 1 | [] | [] | [] | 0 | [
"9fq7",
"9fzl"
] | 2 | [
"PUB00155743"
] | [
"33294524"
] | [
"Transcriptome dataset of <i>Babesia bovis</i> life stages within vertebrate and invertebrate hosts."
] | [
2020
] | 1 | [] | [] | 0 | 0 | null | [
"Sar"
] | [
81
] | 1 | [] | [] | 0 | true | Family | Microprotein, apicomplexa 9 | Microprotein, apicomplexa 9 | Microp_apicomplexa_9 | 7 |
IPR056349 | 56,349 | Microprotein, apicomplexa 10 | Microp_apicomplexa_10 | Family | 124 | false | false | This protein family includes uncharacterised microproteins encoded by small open reading frames (smORFs) from apicomplexa, including from the parasite Babesia bovis [ ]. Members of this family are predicted to fold into a four-stranded antiparallel curved β-sheet followed by a single long α-helix. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23519"
] | [
"Microp_apicomplexa_10"
] | [
124
] | 1 | [] | [] | [] | 0 | [
"9g6k",
"9i05"
] | 2 | [
"PUB00155743"
] | [
"33294524"
] | [
"Transcriptome dataset of <i>Babesia bovis</i> life stages within vertebrate and invertebrate hosts."
] | [
2020
] | 1 | [] | [] | 0 | 0 | null | [
"Sar"
] | [
124
] | 1 | [] | [] | 0 | true | Family | Microprotein, apicomplexa 10 | Microprotein, apicomplexa 10 | Microp_apicomplexa_10 | 1 |
IPR056350 | 56,350 | Pre-mRNA-splicing factor SYF1, central HAT repeats domain | HAT_Syf1_central | Domain | 4,579 | false | false | This entry represents HAT repeats forming the central region of Syf1. This entry includes a group of pre-mRNA-processing factors that are components of the spliceosome, involved in pre-RNA splicing, including Syf1 from human and its homologues from S.pombe, cwf3. These proteins contain HAT (Half A TPR) repeats which ha... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23220"
] | [
"HAT_Syf1_M"
] | [
4579
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOM... | [
"R-DDI-6781823",
"R-DDI-6782135",
"R-DDI-6782210",
"R-DDI-72163",
"R-DME-6781823",
"R-DME-6782135",
"R-DME-6782210",
"R-DME-72163",
"R-HSA-6781823",
"R-HSA-6781827",
"R-HSA-6782135",
"R-HSA-6782210",
"R-HSA-72163",
"R-MMU-6781823",
"R-MMU-6782135",
"R-MMU-6782210",
"R-MMU-72163",
"... | [
"REACTOME:R-DDI-6781823",
"REACTOME:R-DDI-6782135",
"REACTOME:R-DDI-6782210",
"REACTOME:R-DDI-72163",
"REACTOME:R-DME-6781823",
"REACTOME:R-DME-6782135",
"REACTOME:R-DME-6782210",
"REACTOME:R-DME-72163",
"REACTOME:R-HSA-6781823",
"REACTOME:R-HSA-6781827",
"REACTOME:R-HSA-6782135",
"REACTOME:R-... | 28 | [
"5lj3",
"5lj5",
"5lqw",
"5mps",
"5mq0",
"5mqf",
"5xjc",
"5y88",
"5ylz",
"5yzg",
"5z56",
"5z57",
"6bk8",
"6exn",
"6ff7",
"6icz",
"6id0",
"6id1",
"6j6g",
"6j6h",
"6j6n",
"6j6q",
"6qdv",
"7a5p",
"7abi",
"7b9v",
"7dco",
"7w59",
"7w5a",
"7w5b",
"8c6j",
"8ch6"... | 50 | [
"PUB00097019",
"PUB00152085",
"PUB00155642",
"PUB00155643",
"PUB00155644",
"PUB00155645"
] | [
"28076346",
"27459055",
"35705093",
"28076345",
"28919079",
"29146871"
] | [
"Cryo-EM structure of a human spliceosome activated for step 2 of splicing.",
"Cryo-EM structure of the spliceosome immediately after branching.",
"Mechanism of exon ligation by human spliceosome.",
"Structure of a spliceosome remodelled for exon ligation.",
"Structure of an Intron Lariat Spliceosome from S... | [
2017,
2016,
2022,
2017,
2017,
2017
] | 6 | [] | [] | 0 | 0 | null | [
"Eukaryota",
"uncultured Sulfurovum sp."
] | [
4578,
1
] | 2 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Saccharomyces cerevisiae (strai... | [
5,
1,
1,
1,
3,
3,
1,
5,
5,
1,
1,
9
] | 12 | true | Domain | Pre-mRNA-splicing factor SYF1, central HAT repeats domain | Pre-mRNA-splicing factor SYF1, central HAT repeats domain | HAT_Syf1_central | 1 |
IPR056351 | 56,351 | Microprotein domain, apicomplexa 3 | Microp_dom_apicomplexa_3 | Domain | 9 | false | false | This domain covers the whole length of uncharacterised microproteins encoded by small open reading frames (smORFs) from apicomplexa, including from the parasite Babesia bovis [ ], and is found at the N-terminal end of longer uncharacterised proteins from related species. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23522"
] | [
"Microp_apicomplexa_12"
] | [
9
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00155743"
] | [
"33294524"
] | [
"Transcriptome dataset of <i>Babesia bovis</i> life stages within vertebrate and invertebrate hosts."
] | [
2020
] | 1 | [] | [] | 0 | 0 | null | [
"Piroplasmida"
] | [
9
] | 1 | [] | [] | 0 | true | Domain | Microprotein domain, apicomplexa 3 | Microprotein domain, apicomplexa 3 | Microp_dom_apicomplexa_3 | 2 |
IPR056352 | 56,352 | Microprotein, apicomplexa 13 | Microp_apicomplexa_13 | Family | 95 | false | false | This protein family includes uncharacterised microproteins encoded by small open reading frames (smORFs) from apicomplexa, including from the parasite Babesia bovis [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23523"
] | [
"Microp_apicomplexa_13"
] | [
95
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00155743"
] | [
"33294524"
] | [
"Transcriptome dataset of <i>Babesia bovis</i> life stages within vertebrate and invertebrate hosts."
] | [
2020
] | 1 | [] | [] | 0 | 0 | null | [
"Alveolata"
] | [
95
] | 1 | [] | [] | 0 | true | Family | Microprotein, apicomplexa 13 | Microprotein, apicomplexa 13 | Microp_apicomplexa_13 | 4 |
IPR056353 | 56,353 | Microprotein domain, apicomplexa 4 | Microp_dom_apicomplexa_4 | Domain | 7 | false | false | This domain covers the whole length of uncharacterised microproteins encoded by small open reading frames (smORFs) from apicomplexa, including from the parasite Babesia bovis [ ], and is found at the C-terminal end of longer uncharacterised proteins from related species. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23527"
] | [
"Microp_apicomplexa_14"
] | [
7
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00155743"
] | [
"33294524"
] | [
"Transcriptome dataset of <i>Babesia bovis</i> life stages within vertebrate and invertebrate hosts."
] | [
2020
] | 1 | [] | [] | 0 | 0 | null | [
"Babesia"
] | [
7
] | 1 | [] | [] | 0 | true | Domain | Microprotein domain, apicomplexa 4 | Microprotein domain, apicomplexa 4 | Microp_dom_apicomplexa_4 | 4 |
IPR056354 | 56,354 | Microprotein domain, apicomplexa 5 | Microp_dom_apicomplexa_5 | Domain | 53 | false | false | This domain covers the whole length of uncharacterised microproteins encoded by small open reading frames (smORFs) from apicomplexa, including from the parasite Babesia bovis [ ], and is found towards the C terminus of longer uncharacterised proteins from related species. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23528"
] | [
"Microp_apicomplexa_15"
] | [
53
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00155743"
] | [
"33294524"
] | [
"Transcriptome dataset of <i>Babesia bovis</i> life stages within vertebrate and invertebrate hosts."
] | [
2020
] | 1 | [] | [] | 0 | 0 | null | [
"Babesia"
] | [
53
] | 1 | [] | [] | 0 | true | Domain | Microprotein domain, apicomplexa 5 | Microprotein domain, apicomplexa 5 | Microp_dom_apicomplexa_5 | 7 |
IPR056355 | 56,355 | Microprotein, apicomplexa 16 | Microp_apicomplexa_16 | Family | 57 | false | false | This protein family includes uncharacterised microproteins encoded by small open reading frames (smORFs) from apicomplexa, including from the parasite Babesia bovis [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23529"
] | [
"Microp_apicomplexa_16"
] | [
57
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00155743"
] | [
"33294524"
] | [
"Transcriptome dataset of <i>Babesia bovis</i> life stages within vertebrate and invertebrate hosts."
] | [
2020
] | 1 | [] | [] | 0 | 0 | null | [
"Alveolata"
] | [
57
] | 1 | [] | [] | 0 | true | Family | Microprotein, apicomplexa 16 | Microprotein, apicomplexa 16 | Microp_apicomplexa_16 | 7 |
IPR056356 | 56,356 | Microprotein, apicomplexa 17 | Microp_apicomplexa_17 | Family | 111 | false | false | This protein family includes uncharacterised microproteins encoded by small open reading frames (smORFs) from apicomplexa, including from the parasite Babesia bovis [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23531"
] | [
"Microp_apicomplexa_17"
] | [
111
] | 1 | [] | [] | [] | 0 | [
"9fi8",
"9hqv"
] | 2 | [
"PUB00155743"
] | [
"33294524"
] | [
"Transcriptome dataset of <i>Babesia bovis</i> life stages within vertebrate and invertebrate hosts."
] | [
2020
] | 1 | [] | [] | 0 | 0 | null | [
"Alveolata"
] | [
111
] | 1 | [] | [] | 0 | true | Family | Microprotein, apicomplexa 17 | Microprotein, apicomplexa 17 | Microp_apicomplexa_17 | 4 |
IPR056357 | 56,357 | Apc4, C-terminal half WD40 domain, schizosaccharomycetes | Apc4_C_schizosaccharomycetes | Domain | 5 | false | false | Apc4 is a component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. This complex acts by ubiquitination and degradation of target proteins. Apc4 consists of a β-propeller that is split by a long... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23407"
] | [
"WD40_Apc4_C_fungal"
] | [
5
] | 1 | [
"REACTOME"
] | [
"R-SPO-983168"
] | [
"REACTOME:R-SPO-983168"
] | 1 | [] | 0 | [
"PUB00059190",
"PUB00137946"
] | [
"19584054",
"26343760"
] | [
"The transcription factor Atf1 binds and activates the APC/C ubiquitin ligase in fission yeast.",
"Atomic-Resolution Structures of the APC/C Subunits Apc4 and the Apc5 N-Terminal Domain."
] | [
2009,
2015
] | 2 | [] | [] | 0 | 0 | null | [
"Schizosaccharomyces"
] | [
5
] | 1 | [
"Schizosaccharomyces pombe (strain 972 / ATCC 24843)"
] | [
1
] | 1 | true | Domain | Apc4, C-terminal half WD40 domain, schizosaccharomycetes | Apc4, C-terminal half WD40 domain, schizosaccharomycetes | Apc4_C_schizosaccharomycetes | 2 |
IPR056358 | 56,358 | Anaphase-promoting complex subunit 4, C-terminal half WD40 domain | APC4_C | Domain | 1,471 | false | false | Apc4 is a component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. This complex acts by ubiquitination and degradation of target proteins. Apc4 consists of a β-propeller that is split by a long... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23405"
] | [
"WD40_APC4_C-half"
] | [
1471
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOM... | [
"R-HSA-141430",
"R-HSA-174048",
"R-HSA-174084",
"R-HSA-174154",
"R-HSA-174178",
"R-HSA-174184",
"R-HSA-176407",
"R-HSA-176408",
"R-HSA-176409",
"R-HSA-176412",
"R-HSA-179409",
"R-HSA-2467813",
"R-HSA-2559582",
"R-HSA-68867",
"R-HSA-69017",
"R-HSA-8853884",
"R-HSA-9687136",
"R-HSA-9... | [
"REACTOME:R-HSA-141430",
"REACTOME:R-HSA-174048",
"REACTOME:R-HSA-174084",
"REACTOME:R-HSA-174154",
"REACTOME:R-HSA-174178",
"REACTOME:R-HSA-174184",
"REACTOME:R-HSA-176407",
"REACTOME:R-HSA-176408",
"REACTOME:R-HSA-176409",
"REACTOME:R-HSA-176412",
"REACTOME:R-HSA-179409",
"REACTOME:R-HSA-246... | 34 | [
"4ui9",
"5a31",
"5bpt",
"5bpw",
"5g04",
"5g05",
"5khr",
"5khu",
"5l9t",
"5l9u",
"5lcw",
"6q6g",
"6q6h",
"6tlj",
"6tm5",
"6tnt",
"8pkp",
"8tar",
"8tau",
"9gaw",
"9n9r",
"9n9s"
] | 22 | [
"PUB00055977",
"PUB00056269",
"PUB00059190",
"PUB00137946"
] | [
"16896351",
"12049731",
"19584054",
"26343760"
] | [
"The anaphase promoting complex/cyclosome: a machine designed to destroy.",
"The anaphase-promoting complex: proteolysis in mitosis and beyond.",
"The transcription factor Atf1 binds and activates the APC/C ubiquitin ligase in fission yeast.",
"Atomic-Resolution Structures of the APC/C Subunits Apc4 and the A... | [
2006,
2002,
2009,
2015
] | 4 | [] | [] | 0 | 0 | null | [
"Opisthokonta"
] | [
1471
] | 1 | [
"Danio rerio",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
7,
2,
4,
4
] | 4 | true | Domain | Anaphase-promoting complex subunit 4, C-terminal half WD40 domain | Anaphase-promoting complex subunit 4, C-terminal half WD40 domain | APC4_C | 6 |
IPR056359 | 56,359 | ApeC, platyhelminthes | ApeC_platyh | Domain | 49 | false | false | This entry represents a divergent ApeC domain found in a group of proteins mainly from flatworms that also contain . Its specific function is unknown. This domain is predicted to show an α-β configuration. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF24148"
] | [
"ApeC_platyh"
] | [
49
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Platyhelminthes"
] | [
49
] | 1 | [] | [] | 0 | true | Domain | ApeC, platyhelminthes | ApeC, platyhelminthes | ApeC_platyh | 2 |
IPR056360 | 56,360 | ATPase MORC2, chromo domain-like | Chromo_MORC2_6th | Domain | 1,560 | false | false | This domain is found in human ATPase MORC2 and similar sequences predominantly found in vertebrates. MORC2 is essential for epigenetic silencing by the HUSH (human silencing hub) complex. This domain, which is predicted to adopt an α-β configuration, is often found associated with , and . | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23327"
] | [
"Chromo_MORC2_6th"
] | [
1560
] | 1 | [
"EC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"3.6.1.-",
"PWY-5757",
"PWY-6147",
"PWY-6383",
"PWY-6797",
"PWY-7206",
"PWY-7419",
"PWY-7539",
"PWY-7719",
"PWY-7821",
"PWY-8289",
"R-HSA-75105",
"R-HSA-9843970",
"R-MMU-75105"
] | [
"EC:3.6.1.-",
"METACYC:PWY-5757",
"METACYC:PWY-6147",
"METACYC:PWY-6383",
"METACYC:PWY-6797",
"METACYC:PWY-7206",
"METACYC:PWY-7419",
"METACYC:PWY-7539",
"METACYC:PWY-7719",
"METACYC:PWY-7821",
"METACYC:PWY-8289",
"REACTOME:R-HSA-75105",
"REACTOME:R-HSA-9843970",
"REACTOME:R-MMU-75105"
] | 14 | [
"9cdf",
"9cdg",
"9cdh"
] | 3 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
1560
] | 1 | [
"Danio rerio",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
1,
2,
4,
6
] | 4 | true | Domain | ATPase MORC2, chromo domain-like | ATPase MORC2, chromo domain-like | Chromo_MORC2_6th | 1 |
IPR056361 | 56,361 | AtPDCT1/2, transmembrane domain | AtPDCT1_2_TM_dom | Domain | 854 | false | false | This entry represents a domain found in PDCT1/2 from Arabidopsis thaliana, which has a detectable similarity to domains members of the Acid phosphatase/Vanadium-dependent haloperoxidase superfamily and it is predicted to adopt similar structure. This domain is composed of five transmembrane helices. This entry represen... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF24788"
] | [
"AtPDCT1_2"
] | [
854
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00155341",
"PUB00155342",
"PUB00155343"
] | [
"19833868",
"22371508",
"22932756"
] | [
"An enzyme regulating triacylglycerol composition is encoded by the ROD1 gene of Arabidopsis.",
"The phosphatidylcholine diacylglycerol cholinephosphotransferase is required for efficient hydroxy fatty acid accumulation in transgenic Arabidopsis.",
"Acyl editing and headgroup exchange are the major mechanisms t... | [
2009,
2012,
2012
] | 3 | [] | [] | 0 | 0 | null | [
"Eukaryota",
"Pseudomonadati",
"Tupanvirus",
"viral metagenome"
] | [
835,
14,
4,
1
] | 4 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
8,
3,
7
] | 3 | true | Domain | AtPDCT1/2, transmembrane domain | AtPDCT1/2, transmembrane domain | AtPDCT1_2_TM_dom | 3 |
IPR056362 | 56,362 | AtuA-like, ferredoxin-fold domain | AtuA-like_ferredoxin_dom | Domain | 10,221 | false | false | This domain, with a ferredoxin-like fold, is often found at the C-terminal of AtuA-like proteins, although it is sometimes found as a separate protein in the same operon as AtuA. The precise function of this domain is now known. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23544"
] | [
"AtuA_ferredoxin"
] | [
10221
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Methanobacteriota",
"unclassified sequences"
] | [
6425,
3711,
14,
71
] | 4 | [
"Arabidopsis thaliana",
"Danio rerio",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
7,
2,
1,
3,
8
] | 5 | true | Domain | AtuA-like, ferredoxin-fold domain | AtuA-like, ferredoxin-fold domain | AtuA-like_ferredoxin_dom | 1 |
IPR056363 | 56,363 | Leucine-rich repeat and WD repeat-containing protein 1, LRR domain | LRR_LRWD1_dom | Domain | 1,257 | false | false | This entry represents the Leucine-rich repeat domain found at the N terminus of Leucine-rich repeat and WD repeat-containing protein 1 (LRWD1) from animals and related sequences. LRWD1 (also known as CENP-33 and ORCA) is required for for G1/S transition. It recruits and stabilises the origin recognition complex (ORC) o... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23211"
] | [
"LRR_LRWD1"
] | [
1257
] | 1 | [] | [] | [] | 0 | [
"8siy"
] | 1 | [
"PUB00155714",
"PUB00155715",
"PUB00155716"
] | [
"20932478",
"22427655",
"22645314"
] | [
"A WD-repeat protein stabilizes ORC binding to chromatin.",
"Leucine-rich repeat and WD repeat-containing protein 1 is recruited to pericentric heterochromatin by trimethylated lysine 9 of histone H3 and maintains heterochromatin silencing.",
"Dynamic association of ORCA with prereplicative complex components r... | [
2010,
2012,
2012
] | 3 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota"
] | [
20,
1237
] | 2 | [
"Caenorhabditis elegans",
"Danio rerio",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
1,
4,
5,
2,
3
] | 5 | true | Domain | Leucine-rich repeat and WD repeat-containing protein 1, LRR domain | Leucine-rich repeat and WD repeat-containing protein 1, LRR domain | LRR_LRWD1_dom | 7 |
IPR056364 | 56,364 | MABP1/WRD62, coiled-coil domain | WDR62-MABP1_CC | Domain | 1,278 | false | false | This entry represents the coil-coiled domain of WDR62, which is required for its dimerization [ ]. This domain is also found in MABP1. MABP1 (Mitogen-activated protein kinase-binding protein 1) is a negative regulator of NOD2 function, leading to the down-regulation of NOD2-induced processes such as activation of NF-ka... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF24795"
] | [
"WDR62-MABP1_CC"
] | [
1278
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00073161",
"PUB00073163",
"PUB00076882",
"PUB00155315",
"PUB00155369",
"PUB00155370"
] | [
"20729831",
"20890278",
"26297806",
"22700971",
"34137789",
"34137788"
] | [
"Whole-exome sequencing identifies recessive WDR62 mutations in severe brain malformations.",
"Mutations in WDR62, encoding a centrosome-associated protein, cause microcephaly with simplified gyri and abnormal cortical architecture.",
"Centriolar satellites assemble centrosomal microcephaly proteins to recruit ... | [
2010,
2010,
2015,
2012,
2021,
2021
] | 6 | [] | [] | 0 | 0 | null | [
"Gnathostomata"
] | [
1278
] | 1 | [
"Danio rerio",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
10,
13,
8,
10
] | 4 | true | Domain | MABP1/WRD62, coiled-coil domain | MABP1/WRD62, coiled-coil domain | WDR62-MABP1_CC | 6 |
IPR056365 | 56,365 | NAD-specific glutamate dehydrogenase, second domain | NAD-GDH_2nd | Domain | 2,184 | false | false | This domain is found in yeast NAD-specific glutamate dehydrogenase (GDH2, also known as DHE2) [ , ] and similar fungal proteins. GDH2 is involved in the degradation of glutamate to ammonia and alpha-ketoglutarate. This domain is found after that is predicted to adopt an α/β globular structure with some similarity to th... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23152"
] | [
"GDH_2nd"
] | [
2184
] | 1 | [
"EC",
"METACYC",
"METACYC",
"METACYC",
"METACYC"
] | [
"1.4.1.2",
"PWY-5022",
"PWY-6728",
"PWY-7126",
"PWY-8190"
] | [
"EC:1.4.1.2",
"METACYC:PWY-5022",
"METACYC:PWY-6728",
"METACYC:PWY-7126",
"METACYC:PWY-8190"
] | 5 | [] | 0 | [
"PUB00016745",
"PUB00042874"
] | [
"7901008",
"8398079"
] | [
"The role of the NAD-dependent glutamate dehydrogenase in restoring growth on glucose of a Saccharomyces cerevisiae phosphoglucose isomerase mutant.",
"NAD(+)-specific glutamate dehydrogenase of Neurospora crassa: cloning, complete nucleotide sequence, and gene mapping."
] | [
1993,
1993
] | 2 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"marine sediment metagenome"
] | [
3,
2180,
1
] | 3 | [
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)",
"Schizosaccharomyces pombe (strain 972 / ATCC 24843)"
] | [
1,
1,
1
] | 3 | true | Domain | NAD-specific glutamate dehydrogenase, second domain | NAD-specific glutamate dehydrogenase, second domain | NAD-GDH_2nd | 6 |
IPR056366 | 56,366 | Large ribosomal subunit protein eL24 | Ribosomal_eL24 | Family | 10,736 | false | false | This entry represents human Large ribosomal subunit protein eL24 and related proteins from eukaryotes and archaea [ ]. Ribosomal protein eL24/L24 is a ribosomal protein found in eukaryotes (L24) and in archaea (eL24, distinct from archaeal L24). eL24/L24 is located on the surface of the large subunit, adjacent to prote... | [
"GO:0003735"
] | [
"structural constituent of ribosome"
] | [
"molecular_function"
] | 1 | [
"PANTHER"
] | [
"PTHR10792"
] | [
""
] | [
10736
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOM... | [
"R-BTA-156827",
"R-BTA-1799339",
"R-BTA-6791226",
"R-BTA-72689",
"R-BTA-72706",
"R-BTA-975956",
"R-BTA-975957",
"R-CEL-156827",
"R-CEL-1799339",
"R-CEL-72689",
"R-CEL-72706",
"R-CEL-975956",
"R-CEL-975957",
"R-DDI-156827",
"R-DDI-1799339",
"R-DDI-72689",
"R-DDI-72706",
"R-DDI-97595... | [
"REACTOME:R-BTA-156827",
"REACTOME:R-BTA-1799339",
"REACTOME:R-BTA-6791226",
"REACTOME:R-BTA-72689",
"REACTOME:R-BTA-72706",
"REACTOME:R-BTA-975956",
"REACTOME:R-BTA-975957",
"REACTOME:R-CEL-156827",
"REACTOME:R-CEL-1799339",
"REACTOME:R-CEL-72689",
"REACTOME:R-CEL-72706",
"REACTOME:R-CEL-9759... | 69 | [
"2x7n",
"3j6x",
"3j6y",
"3j77",
"3j78",
"3j79",
"3j7o",
"3j7p",
"3j7q",
"3j7r",
"3j92",
"3jag",
"3jah",
"3jai",
"3jaj",
"3jan",
"3jbn",
"3jbo",
"3jbp",
"3jcs",
"3jct",
"4d5y",
"4d67",
"4u3m",
"4u3n",
"4u3u",
"4u4n",
"4u4o",
"4u4q",
"4u4r",
"4u4u",
"4u4y"... | 595 | [
"PUB00007068",
"PUB00007069",
"PUB00007070",
"PUB00080482",
"PUB00080483",
"PUB00080484",
"PUB00153323"
] | [
"11297922",
"11290319",
"11114498",
"15289434",
"17462931",
"15270688",
"36817958"
] | [
"Atomic structures at last: the ribosome in 2000.",
"The ribosome in focus.",
"The end of the beginning: structural studies of ribosomal proteins.",
"Ribosomal protein L24 defect in belly spot and tail (Bst), a mouse Minute.",
"Ribosomal protein L24 is differentially expressed in ovary and testis of the mar... | [
2001,
2001,
2000,
2004,
2007,
2004,
2023
] | 7 | [] | [
"IPR055345"
] | 0 | 1 | 0 | [
"Archaea",
"Eukaryota",
"Gammaproteobacteria",
"ecological metagenomes"
] | [
388,
10336,
2,
10
] | 4 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Saccharomyces cerevisiae (strai... | [
11,
2,
3,
4,
11,
9,
2,
13,
8,
3,
3,
24
] | 12 | true | Family | Large ribosomal subunit protein eL24 | Large ribosomal subunit protein eL24 | Ribosomal_eL24 | 6 |
IPR056367 | 56,367 | ParM | ASKHA_NBD_ParM_R1-like | Family | 1,468 | false | false | Type II plasmid partition systems utilise ParM NTPases in coordination with a centromere-binding protein called ParR to mediate accurate DNA segregation, a process critical for plasmid retention. This entry includes ParM from Escherichia coli (also called ParA locus 36 kDa protein, or protein StbA) and related proteins... | [] | [] | [] | 0 | [
"CDD"
] | [
"cd24022"
] | [
"ASKHA_NBD_ParM_R1-like"
] | [
1468
] | 1 | [] | [] | [] | 0 | [
"1mwk",
"1mwm",
"2qu4",
"2zgy",
"2zgz",
"2zhc",
"3iku",
"3iky",
"4a61",
"4a62",
"4a6j",
"5aey",
"5ai7"
] | 13 | [
"PUB00022210",
"PUB00158760",
"PUB00158761",
"PUB00158762"
] | [
"12486014",
"3023637",
"23112295",
"25915019"
] | [
"F-actin-like filaments formed by plasmid segregation protein ParM.",
"Partitioning of plasmid R1. Structural and functional analysis of the parA locus.",
"A bipolar spindle of antiparallel ParM filaments drives bacterial plasmid segregation.",
"Structures of actin-like ParM filaments show architecture of pla... | [
2002,
1986,
2012,
2015
] | 4 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Caudoviricetes",
"Eukaryota",
"ecological metagenomes"
] | [
1459,
3,
3,
3
] | 4 | [] | [] | 0 | true | Family | ParM | ParM | ASKHA_NBD_ParM_R1-like | 7 |
IPR056368 | 56,368 | Kunitz trypsin inhibitor 1 | KTI1 | Family | 463 | false | false | This entry includes Kunitz trypsin inhibitor 1 (KTI1) from Arabidopsis thaliana and similar proteins which have trypsin protease inhibitor activity. | [] | [] | [] | 0 | [
"CDD"
] | [
"cd00178"
] | [
"beta-trefoil_STI"
] | [
463
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00003281",
"PUB00038061",
"PUB00080394",
"PUB00080395"
] | [
"1738162",
"3611061",
"3905784",
"8834232"
] | [
"beta-Trefoil fold. Patterns of structure and sequence in the Kunitz inhibitors interleukins-1 beta and 1 alpha and fibroblast growth factors.",
"Crystallization and preliminary crystallographic data of the major albumin from Psophocarpus tetragonolobus (L.) DC.",
"Comparative study on amino acid sequences of K... | [
1992,
1987,
1985,
1995
] | 4 | [
"IPR002160"
] | [] | 1 | 0 | 1 | [
"Spermatophyta",
"Staphylococcus warneri"
] | [
460,
3
] | 2 | [
"Arabidopsis thaliana"
] | [
3
] | 1 | true | Family | Kunitz trypsin inhibitor 1 | Kunitz trypsin inhibitor 1 | KTI1 | 7 |
IPR056369 | 56,369 | Cytoplasmic tRNA 2-thiolation protein 1-like, ATP-binding domain | CTU1-like_ATP-bd | Domain | 4,162 | false | false | This entry includes human cytoplasmic tRNA 2-thiolation protein 1, also called cytosolic thiouridylase subunit 1 (CTU1) and ATP-binding domain-containing protein 3 (ATPBD3). CTU1 plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). It directly binds tRNAs a... | [] | [] | [] | 0 | [
"CDD"
] | [
"cd01713"
] | [
"CTU1-like"
] | [
4162
] | 1 | [
"EC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"REACTOME"
] | [
"2.7.7.-",
"PWY-6322",
"PWY-6626",
"PWY-6749",
"PWY-6955",
"PWY-6998",
"PWY-7127",
"PWY-7419",
"PWY-7529",
"PWY-7706",
"PWY-7719",
"PWY-7735",
"PWY-7737",
"PWY-7769",
"PWY-7888",
"PWY-7904",
"PWY-8117",
"PWY-8179",
"R-HSA-6782315"
] | [
"EC:2.7.7.-",
"METACYC:PWY-6322",
"METACYC:PWY-6626",
"METACYC:PWY-6749",
"METACYC:PWY-6955",
"METACYC:PWY-6998",
"METACYC:PWY-7127",
"METACYC:PWY-7419",
"METACYC:PWY-7529",
"METACYC:PWY-7706",
"METACYC:PWY-7719",
"METACYC:PWY-7735",
"METACYC:PWY-7737",
"METACYC:PWY-7769",
"METACYC:PWY-7... | 19 | [
"6scy"
] | 1 | [
"PUB00045305",
"PUB00154400"
] | [
"18391219",
"24906001"
] | [
"The conserved Wobble uridine tRNA thiolase Ctu1-Ctu2 is required to maintain genome integrity.",
"Archaeal Tuc1/Ncs6 homolog required for wobble uridine tRNA thiolation is associated with ubiquitin-proteasome, translation, and RNA processing system homologs."
] | [
2008,
2014
] | 2 | [
"IPR011063"
] | [] | 1 | 0 | 1 | [
"Archaea",
"Eukaryota",
"ecological metagenomes"
] | [
573,
3586,
3
] | 3 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Saccharomyces cerevisiae (strai... | [
8,
1,
3,
1,
1,
1,
1,
3,
1,
1,
1,
6
] | 12 | true | Domain | Cytoplasmic tRNA 2-thiolation protein 1-like, ATP-binding domain | Cytoplasmic tRNA 2-thiolation protein 1-like, ATP-binding domain | CTU1-like_ATP-bd | 7 |
IPR056370 | 56,370 | DE-cadherin-like, Ig-like domain | Shg-like_Ig-like | Domain | 3,328 | false | false | This immunoglobulin-like (Ig-like) domain is found in DE-cadherin from Drosophila melanogaster (Shg) and similar animal sequences. Cadherins are a group of transmembrane proteins that serve as the major adhesion molecules located within adherens junctions. They can regulate cell-cell adhesion through their extracellula... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF24811"
] | [
"Ig_Shg"
] | [
3328
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-DME-1474228",
"R-DME-216083",
"R-DME-351906",
"R-DME-381426",
"R-DME-418990",
"R-DME-5218920",
"R-DME-525793",
"R-DME-8957275",
"R-DME-9762292",
"R-DME-9764561",
"R-DME-9766229",
"R-DME-9768727"
] | [
"REACTOME:R-DME-1474228",
"REACTOME:R-DME-216083",
"REACTOME:R-DME-351906",
"REACTOME:R-DME-381426",
"REACTOME:R-DME-418990",
"REACTOME:R-DME-5218920",
"REACTOME:R-DME-525793",
"REACTOME:R-DME-8957275",
"REACTOME:R-DME-9762292",
"REACTOME:R-DME-9764561",
"REACTOME:R-DME-9766229",
"REACTOME:R-D... | 12 | [] | 0 | [
"PUB00007174",
"PUB00071518"
] | [
"11736639",
"25014356"
] | [
"Structure and functions of classical cadherins.",
"E-Cadherin Can Replace N-Cadherin during Secretory-Stage Enamel Development."
] | [
2001,
2014
] | 2 | [] | [] | 0 | 0 | null | [
"Eumetazoa"
] | [
3328
] | 1 | [
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster"
] | [
2,
3,
7
] | 3 | true | Domain | DE-cadherin-like, Ig-like domain | DE-cadherin-like, Ig-like domain | Shg-like_Ig-like | 3 |
IPR056371 | 56,371 | ATP-dependent RNA helicase DHX37-like, C-terminal domain | DHX37-like_C | Domain | 2,514 | false | false | This domain is found at the C-terminal in human ATP-dependent RNA helicase DHX37 and related proteins. DHX37 is a component of the human SSU processome and plays an important role in processome maturation. This domain folds into an array of α-helices and it is involved in protein-protein interactions with other compone... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23362"
] | [
"DHX37_C"
] | [
2514
] | 1 | [
"EC",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"3.6.4.13",
"R-CEL-6791226",
"R-DME-6791226",
"R-HSA-6790901",
"R-HSA-6791226"
] | [
"EC:3.6.4.13",
"REACTOME:R-CEL-6791226",
"REACTOME:R-DME-6791226",
"REACTOME:R-HSA-6790901",
"REACTOME:R-HSA-6791226"
] | 5 | [
"6o16",
"7mqa"
] | 2 | [
"PUB00151110",
"PUB00155603"
] | [
"34516797",
"30910870"
] | [
"Nucleolar maturation of the human small subunit processome.",
"Molecular mechanism of the RNA helicase DHX37 and its activation by UTP14A in ribosome biogenesis."
] | [
2021,
2019
] | 2 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
2514
] | 1 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Oryza sativa subsp. japonica",
"Rattus norvegicus"
] | [
5,
1,
13,
4,
3,
2,
2,
2
] | 8 | true | Domain | ATP-dependent RNA helicase DHX37-like, C-terminal domain | ATP-dependent RNA helicase DHX37-like, C-terminal domain | DHX37-like_C | 6 |
IPR056373 | 56,373 | Defensin-like domain | Defensin-like_dom | Domain | 499 | false | false | This entry represents a domain found in defensin-like proteins from plants. It may adopt a scorpion toxin-like fold. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF24552"
] | [
"Defensin"
] | [
499
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
499
] | 1 | [
"Arabidopsis thaliana"
] | [
63
] | 1 | true | Domain | Defensin-like domain | Defensin-like domain | Defensin-like_dom | 4 |
IPR056374 | 56,374 | DesK/YvfT, N-terminal domain | DesK/YvfT_N | Domain | 1,520 | false | false | This domain is found at the N-terminal of sensor histidine kinases predominantly found in bacilli, including DesK and YvfT from Bacillus subtilis. DesK is responsible for detecting changes in membrane fluidity during cold stress and activating the response regulator DesR by phosphorylation, which leads to the induction... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23540"
] | [
"DesK_N"
] | [
1520
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00067565",
"PUB00158842",
"PUB00158843",
"PUB00158844"
] | [
"11717295",
"11285232",
"14734164",
"15090506"
] | [
"Comprehensive DNA microarray analysis of Bacillus subtilis two-component regulatory systems.",
"Molecular basis of thermosensing: a two-component signal transduction thermometer in Bacillus subtilis.",
"Genetic evidence for the temperature-sensing ability of the membrane domain of the Bacillus subtilis histidi... | [
2001,
2001,
2004,
2004
] | 4 | [] | [] | 0 | 0 | null | [
"Bacilli"
] | [
1520
] | 1 | [] | [] | 0 | true | Domain | DesK/YvfT, N-terminal domain | DesK/YvfT, N-terminal domain | DesK/YvfT_N | 6 |
IPR056375 | 56,375 | Isopentenyl-diphosphate delta-isomerase, bacteria | Idi_bact | Family | 7,440 | false | false | This entry includes isopentenyl-diphosphate delta-isomerases from bacteria. This entry represents type 1 of two non-homologous families of the enzyme isopentenyl-diphosphate delta-isomerase (IPP isomerase; ). IPP isomerase is a member of the Nudix hydrolase superfamily, and is a key enzyme in the isoprenoid biosyntheti... | [] | [] | [] | 0 | [
"HAMAP"
] | [
"MF_00202"
] | [
"Idi"
] | [
7440
] | 1 | [
"EC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC"
] | [
"5.3.3.2",
"PWY-6174",
"PWY-6383",
"PWY-6859",
"PWY-7102",
"PWY-7391",
"PWY-7524",
"PWY-7560",
"PWY-8125",
"PWY-922"
] | [
"EC:5.3.3.2",
"METACYC:PWY-6174",
"METACYC:PWY-6383",
"METACYC:PWY-6859",
"METACYC:PWY-7102",
"METACYC:PWY-7391",
"METACYC:PWY-7524",
"METACYC:PWY-7560",
"METACYC:PWY-8125",
"METACYC:PWY-922"
] | 10 | [
"1hx3",
"1hzt",
"1i9a",
"1nfs",
"1nfz",
"1ow2",
"1ppv",
"1ppw",
"1pvf",
"1q54",
"1r67",
"1x83",
"1x84",
"2b2k",
"2g73",
"2g74",
"2vnp",
"2vnq",
"3hyq"
] | 19 | [
"PUB00004916",
"PUB00080771"
] | [
"9736763",
"9418296"
] | [
"Differential expression of two isopentenyl pyrophosphate isomerases and enhanced carotenoid accumulation in a unicellular chlorophyte.",
"Isopentenyl diphosphate isomerase: a core enzyme in isoprenoid biosynthesis. A review of its biochemistry and function."
] | [
1998,
1997
] | 2 | [
"IPR011876"
] | [] | 1 | 0 | 1 | [
"Archaea",
"Bacteria",
"Eukaryota",
"metagenomes"
] | [
204,
7189,
4,
43
] | 4 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Isopentenyl-diphosphate delta-isomerase, bacteria | Isopentenyl-diphosphate delta-isomerase, bacteria | Idi_bact | 1 |
IPR056376 | 56,376 | DEX1, C-terminal domain | DEX1_C | Domain | 976 | false | false | Protein defective in exine formation DEX1 is a factor required for proper pollen wall formation in Arabidopsis thaliana and other plant sequences. This entry represents the β-sandwich domain found towards the C-terminal of DEX1 in plants. Mutations in DEX1 are associated with changes in the microspore membrane and prim... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23722"
] | [
"Beta-sand_DEX1"
] | [
976
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00098326",
"PUB00098579"
] | [
"11743117",
"27663411"
] | [
"DEX1, a novel plant protein, is required for exine pattern formation during pollen development in Arabidopsis.",
"A Rice Ca2+ Binding Protein Is Required for Tapetum Function and Pollen Formation."
] | [
2001,
2016
] | 2 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
976
] | 1 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
5,
4,
10
] | 3 | true | Domain | DEX1, C-terminal domain | DEX1, C-terminal domain | DEX1_C | 9 |
IPR056378 | 56,378 | Let-756-like, FGF domain | Let-756-like_FGF | Domain | 657 | false | false | This entry represents the FGF domain of Protein let-756 from Caenorhabditis elegans and similar sequences from invertebrates. Let-756 negatively regulates membrane protrusion from body wall muscles during larval development [ ]. This domain is predicted to adopt a β-trefoil fold. | [] | [] | [] | 0 | [
"CDD"
] | [
"cd00058"
] | [
"beta-trefoil_FGF"
] | [
657
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOM... | [
"R-CEL-1257604",
"R-CEL-190322",
"R-CEL-190370",
"R-CEL-190371",
"R-CEL-190372",
"R-CEL-190373",
"R-CEL-190375",
"R-CEL-190377",
"R-CEL-3000170",
"R-CEL-3000171",
"R-CEL-5654219",
"R-CEL-5654228",
"R-CEL-5654688",
"R-CEL-5654689",
"R-CEL-5654693",
"R-CEL-5654699",
"R-CEL-5654704",
... | [
"REACTOME:R-CEL-1257604",
"REACTOME:R-CEL-190322",
"REACTOME:R-CEL-190370",
"REACTOME:R-CEL-190371",
"REACTOME:R-CEL-190372",
"REACTOME:R-CEL-190373",
"REACTOME:R-CEL-190375",
"REACTOME:R-CEL-190377",
"REACTOME:R-CEL-3000170",
"REACTOME:R-CEL-3000171",
"REACTOME:R-CEL-5654219",
"REACTOME:R-CEL... | 25 | [] | 0 | [
"PUB00001036",
"PUB00021048",
"PUB00022555",
"PUB00024683",
"PUB00036362",
"PUB00036407",
"PUB00067611",
"PUB00067692",
"PUB00081563",
"PUB00081564",
"PUB00081565",
"PUB00081566",
"PUB00086576",
"PUB00156071",
"PUB00156072"
] | [
"7583099",
"11276432",
"11724555",
"10830168",
"9655399",
"8599088",
"8663044",
"16597617",
"7580141",
"8173328",
"8069907",
"11183773",
"16495308",
"2475908",
"20094046"
] | [
"Functions of fibroblast growth factors and their receptors.",
"Fibroblast growth factors.",
"Structural basis for interaction of FGF-1, FGF-2, and FGF-7 with different heparan sulfate motifs.",
"Crystal structures of two FGF-FGFR complexes reveal the determinants of ligand-receptor specificity.",
"Structur... | [
1995,
2001,
2001,
2000,
1998,
1996,
1996,
2006,
1995,
1994,
1994,
2000,
2006,
1989,
2010
] | 15 | [] | [] | 0 | 0 | null | [
"Eumetazoa",
"Ranavirus"
] | [
643,
14
] | 2 | [
"Caenorhabditis elegans"
] | [
1
] | 1 | true | Domain | Let-756-like, FGF domain | Let-756-like, FGF domain | Let-756-like_FGF | 3 |
IPR056379 | 56,379 | DExH14, plug domain | DExH14_plug | Domain | 562 | false | false | This entry represents the plug domain of DExH-box ATP-dependent RNA helicase DExH14 from Arabidopsis, an RNA helicase that plays an essential role in pre-mRNA splicing as component of the U5 snRNP and U4/U6-U5 tri-snRNP complexes. This is a small α-helical bundle domain related to the plug domain of BRR2 proteins ( ). ... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF24557"
] | [
"DExH14_plug"
] | [
562
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Viridiplantae"
] | [
562
] | 1 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
7,
1,
11
] | 3 | true | Domain | DExH14, plug domain | DExH14, plug domain | DExH14_plug | 1 |
IPR056380 | 56,380 | ASCIZ, forth C2H2 zinc finger domain | Znf_C2H2_ASCIZ_4th | Domain | 911 | false | false | This domain is found in the human ATM interactor (also known as ATM/ATR-substrate CHK2-interacting zinc finger protein (ASCIZ)) and related proteins from animals. These proteins are transcription factors that are essential for cell survival and the formation of RAD51 foci, a response to methylating DNA damage [ ]. They... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF24761"
] | [
"C2H2_ASCIZ_4th"
] | [
911
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00014077",
"PUB00035804",
"PUB00035805",
"PUB00035806",
"PUB00035807",
"PUB00035808",
"PUB00035809",
"PUB00035811",
"PUB00035812",
"PUB00043274",
"PUB00155326",
"PUB00155327"
] | [
"12665246",
"17210253",
"15963892",
"15718139",
"10529348",
"11361095",
"10664601",
"10940247",
"11179890",
"18253864",
"15933716",
"17525732"
] | [
"Zinc fingers--folds for many occasions.",
"Sticky fingers: zinc-fingers as protein-recognition motifs.",
"Multiple modes of RNA recognition by zinc finger proteins.",
"Zinc finger proteins: getting a grip on RNA.",
"Zinc finger peptides for the regulation of gene expression.",
"Three classes of C2H2 zinc... | [
2002,
2007,
2005,
2005,
1999,
2001,
2000,
2000,
2001,
2008,
2005,
2007
] | 12 | [
"IPR013087"
] | [] | 1 | 0 | 1 | [
"Eumetazoa"
] | [
911
] | 1 | [
"Danio rerio",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
2,
2,
1,
3
] | 4 | true | Domain | ASCIZ, forth C2H2 zinc finger domain | ASCIZ, forth C2H2 zinc finger domain | Znf_C2H2_ASCIZ_4th | 2 |
IPR056382 | 56,382 | DHX34-like, C2H2-type zinc finger | DHX34_Znf-C2H2 | Domain | 1,134 | false | false | This C2H2-type zinc finger domain is found at the C-terminal end of human Probable ATP-dependent RNA helicase DHX34 and similar animal proteins. DHX34 is required for nonsense-mediated decay degradation of mRNA transcripts containing premature stop codons [ , ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF24485"
] | [
"zf-C2H2_DHX34"
] | [
1134
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00142665",
"PUB00158899"
] | [
"25220460",
"33205750"
] | [
"The RNA helicase DHX34 activates NMD by promoting a transition from the surveillance to the decay-inducing complex.",
"Regulation of RUVBL1-RUVBL2 AAA-ATPases by the nonsense-mediated mRNA decay factor DHX34, as evidenced by Cryo-EM."
] | [
2014,
2020
] | 2 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
1134
] | 1 | [
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
1,
1,
1,
5,
1
] | 5 | true | Domain | DHX34-like, C2H2-type zinc finger | DHX34-like, C2H2-type zinc finger | DHX34_Znf-C2H2 | 7 |
IPR056383 | 56,383 | Diacylglycerol kinase iota-like domain | DGKI-like_dom | Domain | 5,774 | false | false | This domain is found in Diacylglycerol kinase iota (DGKI), zeta (DGKZ) and in DGK2. Diacylglycerol kinase converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids [ ]. This domain is found C-terminal to the catalytic ( ) and accessory ( ) doma... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23578"
] | [
"DGKI"
] | [
5774
] | 1 | [
"EC",
"METACYC",
"METACYC",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"2.7.1.107",
"PWY-7039",
"PWY-7817",
"R-CEL-114508",
"R-DME-114508",
"R-HSA-114508",
"R-MMU-114508",
"R-RNO-114508"
] | [
"EC:2.7.1.107",
"METACYC:PWY-7039",
"METACYC:PWY-7817",
"REACTOME:R-CEL-114508",
"REACTOME:R-DME-114508",
"REACTOME:R-HSA-114508",
"REACTOME:R-MMU-114508",
"REACTOME:R-RNO-114508"
] | 8 | [] | 0 | [
"PUB00103282"
] | [
"15157668"
] | [
"Diacylglycerol kinase zeta regulates phosphatidylinositol 4-phosphate 5-kinase Ialpha by a novel mechanism."
] | [
2004
] | 1 | [] | [] | 0 | 0 | null | [
"Metazoa"
] | [
5774
] | 1 | [
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
5,
83,
9,
12,
8,
15
] | 6 | true | Domain | Diacylglycerol kinase iota-like domain | Diacylglycerol kinase iota-like domain | DGKI-like_dom | 2 |
IPR056384 | 56,384 | At3g06530-like, ARM-repeats domain | ARM_At3g06530 | Domain | 685 | false | false | This is a region of armadillo-like repeats found in the uncharacterised protein At3g06530 from Arabidopsis thaliana and similar plant sequences. This region is normally found associated with . | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF24477"
] | [
"ARM_At3g06530"
] | [
685
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Embryophyta"
] | [
685
] | 1 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
9,
2,
5
] | 3 | true | Domain | At3g06530-like, ARM-repeats domain | At3g06530-like, ARM-repeats domain | ARM_At3g06530 | 8 |
IPR056385 | 56,385 | AVO1/Sin1, ubiquitin-like domain | UBL_AVO1/Sin1 | Domain | 413 | false | false | This domain is found in the Target of rapamycin complex 2 subunit AVO1, subunit sin1 and related proteins from fungi. AVO1 is a component of TORC2, which regulates cell cycle-dependent polarisation of the actin-cytoskeleton and cell wall integrity [ , ]. Sin1 is a component of the SAPK pathway and the mechanistic targe... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23164"
] | [
"UBL_AVO1"
] | [
413
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-SCE-1257604",
"R-SCE-389357",
"R-SCE-5218920",
"R-SCE-6804757",
"R-SCE-9856530",
"R-SPO-1257604",
"R-SPO-389357",
"R-SPO-5218920",
"R-SPO-6804757",
"R-SPO-9856530"
] | [
"REACTOME:R-SCE-1257604",
"REACTOME:R-SCE-389357",
"REACTOME:R-SCE-5218920",
"REACTOME:R-SCE-6804757",
"REACTOME:R-SCE-9856530",
"REACTOME:R-SPO-1257604",
"REACTOME:R-SPO-389357",
"REACTOME:R-SPO-5218920",
"REACTOME:R-SPO-6804757",
"REACTOME:R-SPO-9856530"
] | 10 | [
"6emk"
] | 1 | [
"PUB00011461",
"PUB00015261",
"PUB00061648",
"PUB00158846"
] | [
"10428959",
"12408816",
"16002396",
"28264193"
] | [
"Sin1: an evolutionarily conserved component of the eukaryotic SAPK pathway.",
"Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control.",
"Molecular organization of target of rapamycin complex 2.",
"Substrate specificity of TOR complex 2 is determined by a ubiq... | [
1999,
2002,
2005,
2017
] | 4 | [] | [] | 0 | 0 | null | [
"Opisthokonta"
] | [
413
] | 1 | [
"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)",
"Schizosaccharomyces pombe (strain 972 / ATCC 24843)"
] | [
1,
1
] | 2 | true | Domain | AVO1/Sin1, ubiquitin-like domain | AVO1/Sin1, ubiquitin-like domain | UBL_AVO1/Sin1 | 8 |
IPR056386 | 56,386 | B-cell receptor CD22, first Ig-like domain | Ig_CD22 | Domain | 2,785 | false | false | This is the first immunoglobulin-like (Ig-like) domain found in human B-cell receptor CD22 and similar sequences from vertebrates. CD22 plays a role in various aspects of B-cell biology including differentiation, antigen presentation, and trafficking to bone marrow [ ]. CD22 binds to alpha 2,6-linked sialic acid residu... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF24518"
] | [
"Ig_CD22"
] | [
2785
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-HSA-198933",
"R-HSA-5690714",
"R-HSA-983695",
"R-MMU-198933",
"R-MMU-5690714",
"R-MMU-983695"
] | [
"REACTOME:R-HSA-198933",
"REACTOME:R-HSA-5690714",
"REACTOME:R-HSA-983695",
"REACTOME:R-MMU-198933",
"REACTOME:R-MMU-5690714",
"REACTOME:R-MMU-983695"
] | 6 | [
"5vkj",
"5vkm",
"5vl3"
] | 3 | [
"PUB00158847",
"PUB00158848"
] | [
"20172905",
"34330755"
] | [
"In situ trans ligands of CD22 identified by glycan-protein photocross-linking-enabled proteomics.",
"CD22 Controls Germinal Center B Cell Receptor Signaling, Which Influences Plasma Cell and Memory B Cell Output."
] | [
2010,
2021
] | 2 | [
"IPR003599"
] | [] | 1 | 0 | 1 | [
"Eumetazoa"
] | [
2785
] | 1 | [
"Danio rerio",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
32,
11,
8,
3
] | 4 | true | Domain | B-cell receptor CD22, first Ig-like domain | B-cell receptor CD22, first Ig-like domain | Ig_CD22 | 6 |
IPR056387 | 56,387 | Bacterial deaminase MsddA-like domain | MsddA-like | Domain | 14 | false | false | This domain is found in bacterial deaminases. Some proteins containing this domain also contain RHS repeats. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF24174"
] | [
"MsddA-like"
] | [
14
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Pseudomonadati"
] | [
14
] | 1 | [] | [] | 0 | true | Domain | Bacterial deaminase MsddA-like domain | Bacterial deaminase MsddA-like domain | MsddA-like | 7 |
IPR056388 | 56,388 | YxkI, PH domain | PH_YxkI | Domain | 84 | false | false | This entry represents a bacterial PH domain found in a group of proteins containing a Peptidase M48 domain, including the putative membrane metalloprotease YxkI. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23492"
] | [
"bPH_9"
] | [
84
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillales"
] | [
84
] | 1 | [] | [] | 0 | true | Domain | YxkI, PH domain | YxkI, PH domain | PH_YxkI | 1 |
IPR056389 | 56,389 | Baseplate tube protein p140 | Baseplate_tube_p140 | Family | 231 | false | false | This entry represents the bacteriophage Baseplate tube protein and related proteins, involved in the assembly of the simplified baseplate structure of bacteriophages. Baseplate tube protein p140, interacts with other proteins including the p132 collar protein ring and components of the cone, namely DTP-pb9 and BHP-pb3,... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23779"
] | [
"Baseplate_Tube_p140"
] | [
231
] | 1 | [] | [] | [] | 0 | [
"7qg9",
"7zhj",
"7zn2",
"7zqb",
"8hqz",
"9ioz"
] | 6 | [
"PUB00155631"
] | [
"36961893"
] | [
"Structural basis of bacteriophage T5 infection trigger and <i>E. coli</i> cell wall perforation."
] | [
2023
] | 1 | [] | [] | 0 | 0 | null | [
"Viruses",
"marine metagenome"
] | [
230,
1
] | 2 | [] | [] | 0 | true | Family | Baseplate tube protein p140 | Baseplate tube protein p140 | Baseplate_tube_p140 | 2 |
IPR056391 | 56,391 | Baseplate protein gp9-like, C-terminal | Baseplate_gp9_C | Domain | 565 | false | false | This entry represents the C-terminal domain of Baseplate protein gp9 from Bacteriophage T4, a component of the viral baseplate [ ]. Gp9 connects the long tail fibers of the virus to the baseplate and triggers tail contraction after viral attachment to a host cell. The protein is active as a trimer, with each monomer be... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23618"
] | [
"T4_gp9_10_C"
] | [
565
] | 1 | [] | [] | [] | 0 | [
"1pdp",
"1qex",
"1s2e",
"1tja",
"1zku",
"2fl8",
"2fl9",
"5hx2",
"5iv5",
"5iv7",
"9f4a",
"9f4b"
] | 12 | [
"PUB00010705",
"PUB00016498",
"PUB00040707"
] | [
"10545330",
"12626685",
"16554069"
] | [
"The structure of bacteriophage T4 gene product 9: the trigger for tail contraction.",
"Bacteriophage T4 genome.",
"Evolution of bacteriophage tails: Structure of T4 gene product 10."
] | [
1999,
2003,
2006
] | 3 | [] | [] | 0 | 0 | null | [
"Flagellimonas marina",
"Viruses"
] | [
2,
563
] | 2 | [] | [] | 0 | true | Domain | Baseplate protein gp9-like, C-terminal | Baseplate protein gp9-like, C-terminal | Baseplate_gp9_C | 8 |
IPR056392 | 56,392 | Diacylglycerol kinase theta, RNA-binding domain | DGKtheta_RBD | Domain | 2,192 | false | false | This domain is found in human Diacylglycerol kinase theta (DGKtheta) and similar metazoan proteins. This domain is found between and and is predicted to adopt an RNA-binding domain (RBD)-like fold. DGKtheta converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these ... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF24099"
] | [
"RBD_DGKtheta"
] | [
2192
] | 1 | [
"EC",
"EC",
"METACYC",
"METACYC",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"2.7.1.107",
"2.7.1.93",
"PWY-7039",
"PWY-7817",
"R-HSA-114508",
"R-MMU-114508",
"R-RNO-114508"
] | [
"EC:2.7.1.107",
"EC:2.7.1.93",
"METACYC:PWY-7039",
"METACYC:PWY-7817",
"REACTOME:R-HSA-114508",
"REACTOME:R-MMU-114508",
"REACTOME:R-RNO-114508"
] | 7 | [] | 0 | [
"PUB00114882",
"PUB00114883",
"PUB00145462",
"PUB00145463",
"PUB00158850"
] | [
"17664281",
"15632189",
"15337525",
"11309392",
"23091060"
] | [
"Cyclic AMP-stimulated interaction between steroidogenic factor 1 and diacylglycerol kinase theta facilitates induction of CYP17.",
"Translocation of diacylglycerol kinase theta from cytosol to plasma membrane in response to activation of G protein-coupled receptors and protein kinase C.",
"Nuclear diacylglycer... | [
2007,
2005,
2004,
2001,
2012
] | 5 | [] | [] | 0 | 0 | null | [
"Opisthokonta"
] | [
2192
] | 1 | [
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
5,
1,
7,
5,
1,
1
] | 6 | true | Domain | Diacylglycerol kinase theta, RNA-binding domain | Diacylglycerol kinase theta, RNA-binding domain | DGKtheta_RBD | 9 |
IPR056393 | 56,393 | AprA-like, MT2-like domain | AprA-like_MT2 | Domain | 656 | false | false | This entry represents a methyltransferase domain (MT2-like) found in AprA Methyltransferase 1 from Moorena bouillonii ( ) and similar sequences from bacteria and lower eukaryotes. AprA is an S-adenosylmethionine and Fe3+-dependent dimethyltransferase that acts in the initiation steps of apratoxin A biosynthesis [ , ]. ... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23525"
] | [
"Methyltransf_36"
] | [
656
] | 1 | [] | [] | [] | 0 | [
"6b39",
"6b3a",
"6b3b",
"7uch",
"7uci",
"7ucl"
] | 6 | [
"PUB00155501",
"PUB00155502"
] | [
"29096064",
"35594521"
] | [
"A Mononuclear Iron-Dependent Methyltransferase Catalyzes Initial Steps in Assembly of the Apratoxin A Polyketide Starter Unit.",
"Structural Basis for Control of Methylation Extent in Polyketide Synthase Metal-Dependent <i>C</i>-Methyltransferases."
] | [
2017,
2022
] | 2 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"ecological metagenomes"
] | [
526,
122,
8
] | 3 | [] | [] | 0 | true | Domain | AprA-like, MT2-like domain | AprA-like, MT2-like domain | AprA-like_MT2 | 5 |
IPR056394 | 56,394 | AprA-like, N-terminal domain | AprA-like_N | Domain | 410 | false | false | This entry represents a domain found N-terminal in AprA Methyltransferase 1 from Moorena bouillonii ( ) and similar bacterial sequences. AprA is an S-adenosylmethionine and Fe3+-dependent dimethyltransferase that acts in the initiation steps of apratoxin A biosynthesis [ , ]. This domain has similarity to winged helix ... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23526"
] | [
"AprA_N"
] | [
410
] | 1 | [] | [] | [] | 0 | [
"6b39",
"6b3a",
"6b3b",
"7uch",
"7uci",
"7ucl"
] | 6 | [
"PUB00155501",
"PUB00155502"
] | [
"29096064",
"35594521"
] | [
"A Mononuclear Iron-Dependent Methyltransferase Catalyzes Initial Steps in Assembly of the Apratoxin A Polyketide Starter Unit.",
"Structural Basis for Control of Methylation Extent in Polyketide Synthase Metal-Dependent <i>C</i>-Methyltransferases."
] | [
2017,
2022
] | 2 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"ecological metagenomes"
] | [
395,
6,
9
] | 3 | [] | [] | 0 | true | Domain | AprA-like, N-terminal domain | AprA-like, N-terminal domain | AprA-like_N | 4 |
IPR056397 | 56,397 | Fibronectin-III type-like domain, archaea | Fn3_arc | Domain | 342 | false | false | This domain is found at the C-terminal end of a group of proteins from halobacteria. It is predicted to show structural similarity to the fibronectin type III domain. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23374"
] | [
"Fn3_arc"
] | [
342
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Methanobacteriota"
] | [
342
] | 1 | [] | [] | 0 | true | Domain | Fibronectin-III type-like domain, archaea | Fibronectin-III type-like domain, archaea | Fn3_arc | 3 |
IPR056398 | 56,398 | Coilin, tudor domain | Tudor_Coilin | Domain | 2,224 | false | false | This entry represents the C-terminal domain of coilin which is an atypical Tudor domain that contains large unstructured loops [ ]. Coilin is a nuclear phosphoprotein that serves as an assembly centre in Cajal bodies (CBs) and has a role in small nuclear ribonucleoprotein (snRNP) biogenesis, involved in the modificatio... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23086"
] | [
"Tudor_Coilin"
] | [
2224
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00056623",
"PUB00056626",
"PUB00155892",
"PUB00155893"
] | [
"21289084",
"15862129",
"7679389",
"20875822"
] | [
"Coilin participates in the suppression of RNA polymerase I in response to cisplatin-induced DNA damage.",
"A novel EB-1/AIDA-1 isoform, AIDA-1c, interacts with the Cajal body protein coilin.",
"Assembly of snRNP-containing coiled bodies is regulated in interphase and mitosis--evidence that the coiled body is a... | [
2011,
2005,
1993,
2010
] | 4 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
2224
] | 1 | [
"Arabidopsis thaliana",
"Danio rerio",
"Homo sapiens",
"Mus musculus",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Zea mays"
] | [
2,
1,
1,
3,
3,
6,
17
] | 7 | true | Domain | Coilin, tudor domain | Coilin, tudor domain | Tudor_Coilin | 5 |
IPR056399 | 56,399 | Microprotein, archaea | Microp_archaea | Family | 63 | false | false | This family includes a group of short archaeal proteins encoded by small open reading frames (sORFs) [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF24004"
] | [
"Microp_archaea"
] | [
63
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00155744"
] | [
"37223747"
] | [
"Revealing the small proteome of <i>Haloferax volcanii</i> by combining ribosome profiling and small-protein optimized mass spectrometry."
] | [
2023
] | 1 | [] | [] | 0 | 0 | null | [
"Halobacteriales"
] | [
63
] | 1 | [] | [] | 0 | true | Family | Microprotein, archaea | Microprotein, archaea | Microp_archaea | 3 |
IPR056400 | 56,400 | Cold shock domain-containing protein E1, CSD domain | CSDE1 | Domain | 2,890 | false | false | This entry represents several divergent cold-shock domains found in Cold shock domain-containing protein E1 (CSDE1). These are RNA-binding proteins that play a crucial role in translationally coupled mRNA turnover [ , ]. Members are involved in the cytoplasmic deadenylation, translation, and decay processes, particular... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23456"
] | [
"CSDE1"
] | [
2890
] | 1 | [] | [] | [] | 0 | [
"6y6e",
"6y6m"
] | 2 | [
"PUB00094212",
"PUB00128564",
"PUB00158849"
] | [
"29395067",
"11051545",
"15314026"
] | [
"High-Density Proximity Mapping Reveals the Subcellular Organization of mRNA-Associated Granules and Bodies.",
"A mechanism for translationally coupled mRNA turnover: interaction between the poly(A) tail and a c-fos RNA coding determinant via a protein complex.",
"UNR, a new partner of poly(A)-binding protein, ... | [
2018,
2000,
2004
] | 3 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
2890
] | 1 | [
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
39,
2,
25,
12,
6
] | 5 | true | Domain | Cold shock domain-containing protein E1, CSD domain | Cold shock domain-containing protein E1, CSD domain | CSDE1 | 3 |
IPR056401 | 56,401 | Major capsid protein, crassvirus | Crass_capsid | Family | 138 | false | false | This entry represents the major capsid protein found in crassviruses. The major capsid protein self-assembles to form an icosahedral capsid. In the bacteriophage crAss001, the capsid has a T=9 symmetry and is about 77 nm in diameter. The major capsid protein displays an HK97-like fold with an insertion domain that prot... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23898"
] | [
"Crass_capsid"
] | [
138
] | 1 | [] | [] | [] | 0 | [
"7qof",
"7qoh",
"7qoi",
"8ckb"
] | 4 | [
"PUB00155591"
] | [
"37138077"
] | [
"Structural atlas of a human gut crassvirus."
] | [
2023
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Viruses",
"marine sediment metagenome"
] | [
11,
121,
6
] | 3 | [] | [] | 0 | true | Family | Major capsid protein, crassvirus | Major capsid protein, crassvirus | Crass_capsid | 1 |
IPR056402 | 56,402 | Diels-Alderase, N-terminal domain | DA_N | Domain | 1,341 | false | false | This domain is found at the N-terminal of a number of fungal Diels-Alderases, including cghA, eqx3, poxQ and phmD. In cghA, this domain binds substrate alongside a similarly folded C-terminal domain and achieves catalysis by restricting the movement of the straight-chain substrate into a conformation that facilitates a... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF24137"
] | [
"DA_N"
] | [
1341
] | 1 | [
"EC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC"
] | [
"5.5.1.-",
"PWY-6094",
"PWY-6193",
"PWY-7669",
"PWY-7702",
"PWY-7811",
"PWY-7941",
"PWY-7945",
"PWY-7946"
] | [
"EC:5.5.1.-",
"METACYC:PWY-6094",
"METACYC:PWY-6193",
"METACYC:PWY-7669",
"METACYC:PWY-7702",
"METACYC:PWY-7811",
"METACYC:PWY-7941",
"METACYC:PWY-7945",
"METACYC:PWY-7946"
] | 9 | [
"6kaw",
"6kbc",
"7dmn",
"7dmo",
"7e22",
"7e5t",
"7e5u",
"7e5v"
] | 8 | [
"PUB00093970",
"PUB00100820",
"PUB00153902",
"PUB00155600",
"PUB00155601",
"PUB00155602",
"PUB00160265",
"PUB00160266"
] | [
"31815421",
"25859931",
"34056443",
"26360642",
"28379186",
"35873532",
"2811427",
"30026518"
] | [
"Genomics-Driven Discovery of Phytotoxic Cytochalasans Involved in the Virulence of the Wheat Pathogen Parastagonospora nodorum.",
"Tandem prenyltransferases catalyze isoprenoid elongation and complexity generation in biosynthesis of quinolone alkaloids.",
"Crystal Structures of Fsa2 and Phm7 Catalyzing [4 + 2]... | [
2020,
2015,
2021,
2015,
2017,
2021,
1989,
2018
] | 8 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota"
] | [
38,
1303
] | 2 | [] | [] | 0 | true | Domain | Diels-Alderase, N-terminal domain | Diels-Alderase, N-terminal domain | DA_N | 7 |
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