Datasets:
LiteFold
/
InterPro

Dataset card Data Studio Files
xet
 Community
interpro_id
string
interpro_numeric_id
int64
name
string
short_name
string
entry_type
string
protein_count
int64
is_llm
bool
is_llm_reviewed
bool
abstract
string
go_ids
list
go_terms
list
go_categories
list
go_count
int64
member_databases
list
member_accessions
list
member_names
list
member_protein_counts
list
member_count
int64
external_databases
list
external_accessions
list
external_xrefs
list
external_xref_count
int64
pdb_ids
list
structure_count
int64
publication_ids
list
pubmed_ids
list
publication_titles
list
publication_years
list
publication_count
int64
parent_ids
list
child_ids
list
parent_count
int64
child_count
int64
tree_depth
float64
taxonomy_names
list
taxonomy_protein_counts
list
taxonomy_count
int64
key_species_names
list
key_species_protein_counts
list
key_species_count
int64
in_entry_list
bool
entry_list_type
string
entry_list_name
string
names_dat_name
string
short_names_dat_name
string
split_bucket
int64
IPR056634
56,634
Domain of unknown function DUF7732
DUF7732
Domain
1,108
false
false
This domain is found in uncharacterised proteins mainly from fungi. It contains a set of conserved cysteine residues which are predicted to form a disulfide bond.
[]
[]
[]
0
[ "PFAM" ]
[ "PF24866" ]
[ "DUF7732" ]
[ 1108 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Ascomycota" ]
[ 1108 ]
1
[ "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)" ]
[ 1 ]
1
true
Domain
Domain of unknown function DUF7732
Domain of unknown function DUF7732
DUF7732
4
IPR056635
56,635
Domain of unknown function DUF7733
DUF7733
Domain
1,496
false
false
This domain is found in uncharacterised proteins mainly from plants. It is predicted to fold into a structure consisting of six transmembrane helices.
[]
[]
[]
0
[ "PFAM" ]
[ "PF24867" ]
[ "DUF7733" ]
[ 1496 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Cyanophyceae", "Eukaryota" ]
[ 7, 1489 ]
2
[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]
[ 14, 6, 6 ]
3
true
Domain
Domain of unknown function DUF7733
Domain of unknown function DUF7733
DUF7733
9
IPR056636
56,636
Domain of unknown function DUF7734
DUF7734
Domain
766
false
false
This domain is found in uncharacterised proteins. It is predicted to adopt globular structure consisting of a curved β-sheet and α-helices packed on one side of it. It contains a semi-conserved FKGFSS sequence motif.
[]
[]
[]
0
[ "PFAM" ]
[ "PF24869" ]
[ "DUF7734" ]
[ 766 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria", "Viridiplantae" ]
[ 337, 429 ]
2
[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]
[ 7, 2, 2 ]
3
true
Domain
Domain of unknown function DUF7734
Domain of unknown function DUF7734
DUF7734
3
IPR056637
56,637
Domain of unknown function DUF7735
DUF7735
Domain
482
false
false
This domain is found in uncharacterised proteins mainly from fungi. It is predicted to form a globular structure consisting of α-helices. It contains a set of conserved cysteine residues which are predicted to form disulfide bridges.
[]
[]
[]
0
[ "PFAM" ]
[ "PF24870" ]
[ "DUF7735" ]
[ 482 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "leotiomyceta" ]
[ 482 ]
1
[ "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)" ]
[ 1 ]
1
true
Domain
Domain of unknown function DUF7735
Domain of unknown function DUF7735
DUF7735
2
IPR056639
56,639
Domain of unknown function DUF7737
DUF7737
Domain
1,592
false
false
This domain is found in proteins that contain . The function of this domain is unknown.
[]
[]
[]
0
[ "PFAM" ]
[ "PF24879" ]
[ "DUF7737" ]
[ 1592 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria", "Methanobrevibacter filiformis", "metagenomes" ]
[ 1589, 1, 2 ]
3
[]
[]
0
true
Domain
Domain of unknown function DUF7737
Domain of unknown function DUF7737
DUF7737
1
IPR056640
56,640
Domain of unknown function DUF7738
DUF7738
Domain
563
false
false
This entry represents a family of uncharacterised bacterial protein domains. The structure of these proteins shows some structural similarity to the PePSy domain.
[]
[]
[]
0
[ "PFAM" ]
[ "PF24880" ]
[ "DUF7738" ]
[ 563 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria", "metagenomes" ]
[ 556, 7 ]
2
[]
[]
0
true
Domain
Domain of unknown function DUF7738
Domain of unknown function DUF7738
DUF7738
9
IPR056643
56,643
Domain of unknown function DUF7741
DUF7741
Domain
87
false
false
This is a presumed domain found in a group of uncharacterised sequences from worms. This domain may consist of eight beta-strands.
[]
[]
[]
0
[ "PFAM" ]
[ "PF24888" ]
[ "DUF7741" ]
[ 87 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Chromadorea" ]
[ 87 ]
1
[ "Caenorhabditis elegans" ]
[ 1 ]
1
true
Domain
Domain of unknown function DUF7741
Domain of unknown function DUF7741
DUF7741
4
IPR056645
56,645
Domain of unknown function DUF7743
DUF7743
Domain
350
false
false
This is a presumed domain of unknown function found in uncharacterised proteins from Dictyosteliales. It may adopt a Ig-like fold.
[]
[]
[]
0
[ "PFAM" ]
[ "PF24893" ]
[ "DUF7743" ]
[ 350 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Archaea", "Bacteria", "Dictyostelia", "marine sediment metagenome" ]
[ 4, 27, 317, 2 ]
4
[]
[]
0
true
Domain
Domain of unknown function DUF7743
Domain of unknown function DUF7743
DUF7743
2
IPR056646
56,646
Domain of unknown function DUF7744
DUF7744
Domain
39
false
false
This entry represents the C-terminal domain of a small set of proteins belonging to the . Structure prediction suggests that this domain may mediate dimerisation.
[]
[]
[]
0
[ "PFAM" ]
[ "PF24897" ]
[ "DUF7744" ]
[ 39 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria" ]
[ 39 ]
1
[]
[]
0
true
Domain
Domain of unknown function DUF7744
Domain of unknown function DUF7744
DUF7744
7
IPR056647
56,647
Domain of unknown function DUF7745
DUF7745
Domain
9,487
false
false
This domain is found in uncharacterised proteins mainly from plants. It has detectable similarity to plant mobile domains and it is predicted to adopt similar structure.
[]
[]
[]
0
[ "PFAM" ]
[ "PF24924" ]
[ "DUF7745" ]
[ 9487 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bifidobacterium breve", "Mesangiospermae" ]
[ 1, 9486 ]
2
[]
[]
0
true
Domain
Domain of unknown function DUF7745
Domain of unknown function DUF7745
DUF7745
9
IPR056649
56,649
Domain of unknown function DUF7747
DUF7747
Domain
172
false
false
This domain is found in uncharacterised protein ZK892.6 from Caenorhabditis elegans and related proteins. It is found either standalone or in combination with other domains. Some proteins contain multiple copies of this domain. It is predicted to adopt a globular structure consisting of an antiparallel six-stranded β-s...
[]
[]
[]
0
[ "PFAM" ]
[ "PF24927" ]
[ "DUF7747" ]
[ 172 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Rhabditida" ]
[ 172 ]
1
[ "Caenorhabditis elegans" ]
[ 5 ]
1
true
Domain
Domain of unknown function DUF7747
Domain of unknown function DUF7747
DUF7747
6
IPR056650
56,650
Domain of unknown function DUF7748
DUF7748
Domain
182
false
false
This domain is found in uncharacterised proteins from plants. It is predicted to fold into a β-sandwich.
[]
[]
[]
0
[ "PFAM" ]
[ "PF24928" ]
[ "DUF7748" ]
[ 182 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Embryophyta" ]
[ 182 ]
1
[]
[]
0
true
Domain
Domain of unknown function DUF7748
Domain of unknown function DUF7748
DUF7748
4
IPR056651
56,651
Ras guanine nucleotide exchange factor glfB-like, C-terminal
GlfB-like_C
Domain
171
false
false
This domain is found at the C-terminal of Ras guanine nucleotide exchange factor glfB from Dictyostelium discoideum and in similar uncharacterised proteins from lower eukaryotes. GflB is a GpaB-activated, rapA-specific guanine nucleotide exchange factor, involved in the regulation of the balance between Ras and Rap sig...
[]
[]
[]
0
[ "PFAM" ]
[ "PF24929" ]
[ "GlfB_C" ]
[ 171 ]
1
[]
[]
[]
0
[]
0
[ "PUB00159973", "PUB00159974", "PUB00159975" ]
[ "27237792", "28778987", "29626371" ]
[ "A Gα-Stimulated RapGEF Is a Receptor-Proximal Regulator of Dictyostelium Chemotaxis.", "The F-actin-binding RapGEF GflB is required for efficient macropinocytosis in <i>Dictyostelium</i>.", "Phosphodiesterase PdeD, dynacortin, and a Kelch repeat-containing protein are direct GSK3 substrates in Dictyostelium th...
[ 2016, 2017, 2018 ]
3
[]
[]
0
0
null
[ "Eukaryota" ]
[ 171 ]
1
[]
[]
0
true
Domain
Ras guanine nucleotide exchange factor glfB-like, C-terminal
Ras guanine nucleotide exchange factor glfB-like, C-terminal
GlfB-like_C
5
IPR056652
56,652
Domain of unknown function DUF7750
DUF7750
Domain
699
false
false
This is a domain of unknown function found in plant sequences. It may adopt a three-helical bundle fold.
[]
[]
[]
0
[ "PFAM" ]
[ "PF24930" ]
[ "DUF7750" ]
[ 699 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Streptophyta" ]
[ 699 ]
1
[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]
[ 13, 1, 21 ]
3
true
Domain
Domain of unknown function DUF7750
Domain of unknown function DUF7750
DUF7750
8
IPR056653
56,653
Domain of unknown function DUF7751
DUF7751
Domain
5,142
false
false
This domain is found in a group of uncharacterised plant proteins with the AAA domain ( ). This domain is predicted to adopt an all alpha configuration.
[]
[]
[]
0
[ "PFAM" ]
[ "PF24933" ]
[ "DUF7751" ]
[ 5142 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Eukaryota" ]
[ 5142 ]
1
[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]
[ 59, 21, 144 ]
3
true
Domain
Domain of unknown function DUF7751
Domain of unknown function DUF7751
DUF7751
9
IPR056654
56,654
Domain of unknown function DUF7752
DUF7752
Domain
440
false
false
This domain is found in a group of uncharacterised animal proteins that also contain . This domain is predicted to adopt a mainly α-helical structure. Its specific function is unknown.
[]
[]
[]
0
[ "PFAM" ]
[ "PF24934" ]
[ "DUF7752" ]
[ 440 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bilateria" ]
[ 440 ]
1
[ "Caenorhabditis elegans" ]
[ 5 ]
1
true
Domain
Domain of unknown function DUF7752
Domain of unknown function DUF7752
DUF7752
9
IPR056655
56,655
Domain of unknown function DUF7753
DUF7753
Domain
127
false
false
This is a presumed domain found at the C-terminal of a group of worm proteins. This domain may adopt a hairpin fold.
[]
[]
[]
0
[ "PFAM" ]
[ "PF24936" ]
[ "DUF7753" ]
[ 127 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Nematoda" ]
[ 127 ]
1
[ "Caenorhabditis elegans" ]
[ 1 ]
1
true
Domain
Domain of unknown function DUF7753
Domain of unknown function DUF7753
DUF7753
8
IPR056656
56,656
Domain of unknown function DUF7754
DUF7754
Domain
181
false
false
This is a presumed domain found at the C-terminal of worm proteins. It may be related to BACK domains.
[]
[]
[]
0
[ "PFAM" ]
[ "PF24937" ]
[ "DUF7754" ]
[ 181 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Rhabditida" ]
[ 181 ]
1
[ "Caenorhabditis elegans" ]
[ 1 ]
1
true
Domain
Domain of unknown function DUF7754
Domain of unknown function DUF7754
DUF7754
1
IPR056657
56,657
Domain of unknown function DUF7755
DUF7755
Domain
609
false
false
This is a domain of unknown function found in plants. This domain is structurally related to Lipase/lipooxygenase domain (PLAT/LH2 domain).
[]
[]
[]
0
[ "PFAM" ]
[ "PF24938" ]
[ "DUF7755" ]
[ 609 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Viridiplantae" ]
[ 609 ]
1
[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]
[ 7, 2, 5 ]
3
true
Domain
Domain of unknown function DUF7755
Domain of unknown function DUF7755
DUF7755
1
IPR056658
56,658
Domain of unknown function DUF7756
DUF7756
Domain
14
false
false
This is a presumed domain found in sequences from Strongyloides stercoralis and similar worms. It may adopt a β-sandwich fold related to MATh domains.
[]
[]
[]
0
[ "PFAM" ]
[ "PF24939" ]
[ "DUF7756" ]
[ 14 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Strongyloidoidea" ]
[ 14 ]
1
[]
[]
0
true
Domain
Domain of unknown function DUF7756
Domain of unknown function DUF7756
DUF7756
6
IPR056659
56,659
Domain of unknown function DUF7757
DUF7757
Domain
6
false
false
This is a presumed domain found at the N-terminal of a set of sequences from Strongyloides stercoralis and similar worms. It may adopt a β-sandwich fold, related to MATH domains.
[]
[]
[]
0
[ "PFAM" ]
[ "PF24941" ]
[ "DUF7757" ]
[ 6 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Strongyloididae" ]
[ 6 ]
1
[]
[]
0
true
Domain
Domain of unknown function DUF7757
Domain of unknown function DUF7757
DUF7757
7
IPR056660
56,660
Repeat of unknown function DUF7758
DUF7758
Domain
137
false
false
This domain is found in uncharacterised proteins mainly from nematodes. It is composed of repetitive α-helical hairpins and has detectable similarity to 14-3-3 proteins.
[]
[]
[]
0
[ "PFAM" ]
[ "PF24944" ]
[ "DUF7758" ]
[ 137 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Rhabditida" ]
[ 137 ]
1
[ "Caenorhabditis elegans" ]
[ 3 ]
1
true
Domain
Repeat of unknown function DUF7758
Repeat of unknown function DUF7758
DUF7758
1
IPR056662
56,662
Domain of unknown function DUF7760
DUF7760
Domain
47
false
false
This domain is found in uncharacterised proteins mainly from flagellate Discoba. It is predicted to adopt a globular structure consisting of array of helices.
[]
[]
[]
0
[ "PFAM" ]
[ "PF24949" ]
[ "DUF7760" ]
[ 47 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Eukaryota" ]
[ 47 ]
1
[]
[]
0
true
Domain
Domain of unknown function DUF7760
Domain of unknown function DUF7760
DUF7760
3
IPR056663
56,663
Domain of unknown function DUF7761
DUF7761
Domain
103
false
false
This domain is found in uncharacterised proteins mainly from flagellate Discoba.
[]
[]
[]
0
[ "PFAM" ]
[ "PF24952" ]
[ "DUF7761" ]
[ 103 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Trypanosomatidae" ]
[ 103 ]
1
[]
[]
0
true
Domain
Domain of unknown function DUF7761
Domain of unknown function DUF7761
DUF7761
6
IPR056664
56,664
Domain of unknown function DUF7762
DUF7762
Domain
117
false
false
This domain is found in uncharacterised proteins mainly from Trypanosomatidae lineage. It has detectable similarity to known PDZ domains and it is predicted to adopt similar structure. It is frequently found in multiple tandem copies.
[]
[]
[]
0
[ "PFAM" ]
[ "PF24953" ]
[ "DUF7762" ]
[ 117 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Trypanosomatidae" ]
[ 117 ]
1
[]
[]
0
true
Domain
Domain of unknown function DUF7762
Domain of unknown function DUF7762
DUF7762
6
IPR056665
56,665
Domain of unknown function DUF7763
DUF7763
Domain
161
false
false
This domain is found in uncharacterised proteins mainly from Streptococcus. It is predicted to adopt globular structure consisting of four α-helices.
[]
[]
[]
0
[ "PFAM" ]
[ "PF24954" ]
[ "DUF7763" ]
[ 161 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria" ]
[ 161 ]
1
[]
[]
0
true
Domain
Domain of unknown function DUF7763
Domain of unknown function DUF7763
DUF7763
8
IPR056666
56,666
DISARM protein DrmE, C-terminal
DrmE_C
Domain
191
false
false
This domain is found at the C-terminal end of DISARM protein DrmE from Bacillus paralicheniformis and similar uncharacterised prokaryotic proteins. DrmE is a component of antiviral defense system DISARM (defense island system associated with restriction-modification), composed of DrmE, DrmA, DrmB, DrmC and DrmMII. DISA...
[]
[]
[]
0
[ "PFAM" ]
[ "PF24957" ]
[ "DrmE_C" ]
[ 191 ]
1
[]
[]
[]
0
[]
0
[ "PUB00105719" ]
[ "29085076" ]
[ "DISARM is a widespread bacterial defence system with broad anti-phage activities." ]
[ 2018 ]
1
[]
[]
0
0
null
[ "Bacteria", "Mesorhabditis spiculigera", "Methanobacteriota", "ecological metagenomes" ]
[ 154, 1, 29, 7 ]
4
[]
[]
0
true
Domain
DISARM protein DrmE, C-terminal
DISARM protein DrmE, C-terminal
DrmE_C
2
IPR056668
56,668
Outer surface lipoprotein BB0158
BB0158-like
Domain
211
false
false
This domain, previously known as DUF7766, is found in Outer surface lipoprotein BB0158 from Borrelia burgdorferi and related proteins mainly from Spirochaetales. It folds into a double β-barrel structure capped with α-helices . This domain forms a swapped dimer in which the N-terminal β-strand from one monomer is repla...
[]
[]
[]
0
[ "NCBIFAM", "PFAM" ]
[ "NF033723", "PF24960" ]
[ "S2_P23", "BB0158" ]
[ 154, 211 ]
2
[]
[]
[]
0
[ "8q4k" ]
1
[ "PUB00019466", "PUB00160310" ]
[ "10672174", "38016210" ]
[ "A bacterial genome in flux: the twelve linear and nine circular extrachromosomal DNAs in an infectious isolate of the Lyme disease spirochete Borrelia burgdorferi.", "Structural studies of chromosomally encoded outer surface lipoprotein BB0158 from Borrelia burgdorferi sensu stricto." ]
[ 2000, 2024 ]
2
[]
[]
0
0
null
[ "Borreliaceae" ]
[ 211 ]
1
[]
[]
0
true
Domain
Outer surface lipoprotein BB0158
Outer surface lipoprotein BB0158
BB0158-like
7
IPR056669
56,669
Domain of unknown function DUF7767
DUF7767
Domain
861
false
false
This is a domain of unknown function found at the C-terminal of fungal sequences. It may adopt a ubiquitin-like fold.
[]
[]
[]
0
[ "PFAM" ]
[ "PF24962" ]
[ "DUF7767" ]
[ 861 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Opisthokonta" ]
[ 861 ]
1
[ "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)" ]
[ 2 ]
1
true
Domain
Domain of unknown function DUF7767
Domain of unknown function DUF7767
DUF7767
8
IPR056670
56,670
Domain of unknown function DUF7768
DUF7768
Domain
1,962
false
false
This entry represents a domain found in uncharacterised bacterial proteins. It has a detectable similarity to domains members of N-(deoxy)ribosyltransferase-like superfamily and is predicted to adopt similar structure.
[]
[]
[]
0
[ "PFAM" ]
[ "PF24963" ]
[ "DUF7768" ]
[ 1962 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Archaea", "Bacteria", "Viruses", "unclassified sequences" ]
[ 6, 1734, 130, 92 ]
4
[]
[]
0
true
Domain
Domain of unknown function DUF7768
Domain of unknown function DUF7768
DUF7768
2
IPR056671
56,671
Domain of unknown function DUF7769
DUF7769
Domain
1,406
false
false
This is a presumed domain found in plant sequences. It may consist in a tri-helical fold.
[]
[]
[]
0
[ "PFAM" ]
[ "PF24964" ]
[ "DUF7769" ]
[ 1406 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Eukaryota" ]
[ 1406 ]
1
[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica" ]
[ 1, 69 ]
2
true
Domain
Domain of unknown function DUF7769
Domain of unknown function DUF7769
DUF7769
8
IPR056672
56,672
Domain of unknown function DUF7770
DUF7770
Domain
1,078
false
false
This entry represents a domain found in uncharacterised proteins. It is predicted to adopt a globular structure that resembles the conserved core of the PPPDE superfamily (after Permuted Papain fold Peptidases of DsRNA viruses and Eukaryotes) which consists of thiol peptidases with a circularly permuted papain-like fol...
[]
[]
[]
0
[ "PFAM" ]
[ "PF24968" ]
[ "DUF7770" ]
[ 1078 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Eukaryota" ]
[ 1078 ]
1
[]
[]
0
true
Domain
Domain of unknown function DUF7770
Domain of unknown function DUF7770
DUF7770
8
IPR056673
56,673
Domain of unknown function DUF7771
DUF7771
Domain
188
false
false
This domain is found in uncharacterised plant proteins. It is predicted to fold into a β-sandwich with structural similarity to Transthyretin-like domains in particular to SPH (Self-Incompatibility Protein Homologue) proteins.
[]
[]
[]
0
[ "PFAM" ]
[ "PF24974" ]
[ "DUF7771" ]
[ 188 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Poales" ]
[ 188 ]
1
[ "Oryza sativa subsp. japonica", "Zea mays" ]
[ 15, 6 ]
2
true
Domain
Domain of unknown function DUF7771
Domain of unknown function DUF7771
DUF7771
2
IPR056674
56,674
Protein of unknown function DUF7772
DUF7772
Family
166
false
false
This entry represents a group of uncharacterised worm proteins. They contain highly conserved cysteine residues that are predicted to form disulfide bonds. It is likely that these proteins are secreted.
[]
[]
[]
0
[ "PFAM", "PANTHER" ]
[ "PF24977", "PTHR31330" ]
[ "DUF7772", "" ]
[ 166, 151 ]
2
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Rhabditina" ]
[ 166 ]
1
[ "Caenorhabditis elegans" ]
[ 12 ]
1
true
Family
Protein of unknown function DUF7772
Protein of unknown function DUF7772
DUF7772
9
IPR056676
56,676
Domain of unknown function DUF7774
DUF7774
Domain
266
false
false
This domain is found in uncharacterised worm proteins mainly from clade Rhabditida. It is predicted to adopt a globular structure composed of array of α-helices.
[]
[]
[]
0
[ "PFAM" ]
[ "PF24983" ]
[ "DUF7774" ]
[ 266 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Rhabditida" ]
[ 266 ]
1
[ "Caenorhabditis elegans" ]
[ 5 ]
1
true
Domain
Domain of unknown function DUF7774
Domain of unknown function DUF7774
DUF7774
5
IPR056677
56,677
Domain of unknown function DUF7775
DUF7775
Domain
460
false
false
This domain is found in uncharacterised insect proteins mainly from clade Diptera. It is predicted to fold into a four helical bundle which shares detectable similarity to Marvel-like domains. Some proteins contain two copies of this domain. It is likely to be associated with membrane.
[]
[]
[]
0
[ "PFAM" ]
[ "PF24985" ]
[ "DUF7775" ]
[ 460 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Pterygota" ]
[ 460 ]
1
[ "Drosophila melanogaster" ]
[ 9 ]
1
true
Domain
Domain of unknown function DUF7775
Domain of unknown function DUF7775
DUF7775
5
IPR056678
56,678
Domain of unknown function DUF7776
DUF7776
Domain
325
false
false
This domain is found in HFX_2341 from Haloferax mediterranei and similar archaeal proteins. HFX_2341 is a global regulator involved in cas gene regulation. This domain is often found associated with .
[]
[]
[]
0
[ "PFAM" ]
[ "PF24989" ]
[ "DUF7776" ]
[ 325 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Halobacteria" ]
[ 325 ]
1
[]
[]
0
true
Domain
Domain of unknown function DUF7776
Domain of unknown function DUF7776
DUF7776
8
IPR056679
56,679
Domain of unknown function DUF7777
DUF7777
Domain
982
false
false
This domain is found exclusively in Trichomonas proteins. It is predicted to fold into an α/β structure.
[]
[]
[]
0
[ "PFAM" ]
[ "PF24992" ]
[ "DUF7777" ]
[ 982 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Trichomonas vaginalis (strain ATCC PRA-98 / G3)" ]
[ 982 ]
1
[]
[]
0
true
Domain
Domain of unknown function DUF7777
Domain of unknown function DUF7777
DUF7777
5
IPR056681
56,681
Domain of unknown function DUF7779
DUF7779
Domain
6,161
false
false
This is a presumed domain found in uncharacterised sequences from fungi. It may be a winged helix domain according to structure predictions.
[]
[]
[]
0
[ "PFAM" ]
[ "PF25000" ]
[ "DUF7779" ]
[ 6161 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria", "Eukaryota", "Methanosarcinales", "metagenomes" ]
[ 2230, 3919, 9, 3 ]
4
[ "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)" ]
[ 1 ]
1
true
Domain
Domain of unknown function DUF7779
Domain of unknown function DUF7779
DUF7779
2
IPR056682
56,682
Domain of unknown function DUF7780
DUF7780
Domain
634
false
false
This domain is found in uncharacterised plant proteins. It has a detectable similarity to known glycosyltransferases clan GT-A and is predicted to adopt similar structure.
[]
[]
[]
0
[ "PFAM" ]
[ "PF25002" ]
[ "DUF7780" ]
[ 634 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Streptophyta" ]
[ 634 ]
1
[ "Arabidopsis thaliana" ]
[ 12 ]
1
true
Domain
Domain of unknown function DUF7780
Domain of unknown function DUF7780
DUF7780
3
IPR056683
56,683
Domain of unknown function DUF7781
DUF7781
Domain
720
false
false
This domain is found in uncharacterised plant proteins. It is predicted to fold into a β-meander that coils to form an open barrel-like structure.
[]
[]
[]
0
[ "PFAM" ]
[ "PF25003" ]
[ "DUF7781" ]
[ 720 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Eukaryota" ]
[ 720 ]
1
[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]
[ 9, 3, 3 ]
3
true
Domain
Domain of unknown function DUF7781
Domain of unknown function DUF7781
DUF7781
1
IPR056684
56,684
Domain of unknown function DUF7782
DUF7782
Domain
2,673
false
false
This is a presumed domain found at the C-terminal of a group of uncharacterised sequences from Nocardia sp. According to structure predictions, this domain may adopt a winged helix fold with an insertion consisting of a long β-hairpin and a short β-strand.
[]
[]
[]
0
[ "PFAM" ]
[ "PF25004" ]
[ "DUF7782" ]
[ 2673 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria", "metagenomes" ]
[ 2667, 6 ]
2
[]
[]
0
true
Domain
Domain of unknown function DUF7782
Domain of unknown function DUF7782
DUF7782
3
IPR056685
56,685
Domain of unknown function DUF7783
DUF7783
Domain
1,805
false
false
This domain is found in uncharacterised fungal proteins. It is predicted to fold into a four-helical up-and-down bundle. It has a detectable similarity to Talin 1-like four-helical domains.
[]
[]
[]
0
[ "PFAM" ]
[ "PF25006" ]
[ "DUF7783" ]
[ 1805 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Eukaryota" ]
[ 1805 ]
1
[ "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)" ]
[ 1 ]
1
true
Domain
Domain of unknown function DUF7783
Domain of unknown function DUF7783
DUF7783
8
IPR056686
56,686
Domain of unknown function DUF7784
DUF7784
Domain
1,137
false
false
This domain is found in uncharacterised fungal proteins. It is predicted to adopt an up-and-down four-helical bundle.
[]
[]
[]
0
[ "PFAM" ]
[ "PF25008" ]
[ "DUF7784" ]
[ 1137 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Eukaryota" ]
[ 1137 ]
1
[ "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)" ]
[ 1 ]
1
true
Domain
Domain of unknown function DUF7784
Domain of unknown function DUF7784
DUF7784
4
IPR056687
56,687
Domain of unknown function DUF7785
DUF7785
Domain
1,025
false
false
This is a presumed domain found in a group of uncharacterised fungal sequences.
[]
[]
[]
0
[ "PFAM" ]
[ "PF25009" ]
[ "DUF7785" ]
[ 1025 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Eukaryota" ]
[ 1025 ]
1
[ "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)" ]
[ 1 ]
1
true
Domain
Domain of unknown function DUF7785
Domain of unknown function DUF7785
DUF7785
1
IPR056689
56,689
Domain of unknown function DUF7787
DUF7787
Domain
553
false
false
This domain is found in uncharacterised plant proteins. It contains the so-called HeH motif (helix-extended loop-helix). This motif is known to engage in protein-protein and/or nucleic acid interactions. Some proteins contain two copies of this domain.
[]
[]
[]
0
[ "PFAM" ]
[ "PF25042" ]
[ "DUF7787" ]
[ 553 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Mesangiospermae" ]
[ 553 ]
1
[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]
[ 4, 5, 3 ]
3
true
Domain
Domain of unknown function DUF7787
Domain of unknown function DUF7787
DUF7787
5
IPR056690
56,690
Domain of unknown function DUF7788
DUF7788
Domain
4,163
false
false
This is a vWA-like domain found at the C-terminal of uncharacterised proteins containing at the N-terminal [ ].
[]
[]
[]
0
[ "PFAM" ]
[ "PF25043" ]
[ "DUF7788" ]
[ 4163 ]
1
[]
[]
[]
0
[]
0
[ "PUB00152793" ]
[ "36419248" ]
[ "DALI shines a light on remote homologs: One hundred discoveries." ]
[ 2023 ]
1
[]
[]
0
0
null
[ "Bacteria", "Eukaryota", "Methanobrevibacter millerae", "Viruses", "metagenomes" ]
[ 198, 3534, 2, 331, 98 ]
5
[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]
[ 21, 14, 8 ]
3
true
Domain
Domain of unknown function DUF7788
Domain of unknown function DUF7788
DUF7788
5
IPR056691
56,691
Domain of unknown function DUF7789
DUF7789
Domain
826
false
false
This domain is found in uncharacterised eukaryotic proteins. It is predicted to fold into a four-helical up-and-down bundle. It is usually found in two tandem copies. This domain is likely associated with the membrane.
[]
[]
[]
0
[ "PFAM" ]
[ "PF25044" ]
[ "DUF7789" ]
[ 826 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Epilithonimonas zeae", "Eukaryota" ]
[ 1, 825 ]
2
[]
[]
0
true
Domain
Domain of unknown function DUF7789
Domain of unknown function DUF7789
DUF7789
3
IPR056692
56,692
Domain of unknown function DUF7790
DUF7790
Domain
267
false
false
This domain is found in uncharacterised protein from Leptospira interrogans serogroup Icterohaemorrhagiae serovar Copenhageni and related bacterial proteins. Its structure was determined ( ) and shares a significant similarity to various methyltransferases.
[]
[]
[]
0
[ "NCBIFAM", "PFAM" ]
[ "NF047518", "PF25046" ]
[ "LIC_10091_fam", "DUF7790" ]
[ 169, 267 ]
2
[]
[]
[]
0
[ "6ulo" ]
1
[ "PUB00159350", "PUB00159360" ]
[ "38204132", "21221970" ]
[ "Cleavage of cell junction proteins as a host invasion strategy in leptospirosis.", "Characterization of the immunogenic and antigenic potential of putative lipoproteins from Leptospira interrogans." ]
[ 2024, 2011 ]
2
[]
[]
0
0
null
[ "Bacteria", "marine metagenome" ]
[ 266, 1 ]
2
[]
[]
0
true
Domain
Domain of unknown function DUF7790
Domain of unknown function DUF7790
DUF7790
5
IPR056693
56,693
Domain of unknown function DUF7791
DUF7791
Domain
4,214
false
false
This domain is found in a group of uncharacterised fungal proteins that also contain the domain at its N-terminal end. This domain is predicted to have a mainly α-helical configuration.
[]
[]
[]
0
[ "PFAM" ]
[ "PF25053" ]
[ "DUF7791" ]
[ 4214 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Eukaryota" ]
[ 4214 ]
1
[ "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)" ]
[ 3 ]
1
true
Domain
Domain of unknown function DUF7791
Domain of unknown function DUF7791
DUF7791
3
IPR056694
56,694
Domain of unknown function DUF7792
DUF7792
Domain
2,675
false
false
This domain is found N-terminal in uncharacterised eukaryotic proteins. It has detectable similarity to domains members of the MLKL N-terminal domain superfamily and is predicted to adopt similar structure.
[]
[]
[]
0
[ "PFAM" ]
[ "PF25055" ]
[ "DUF7792" ]
[ 2675 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Viridiplantae" ]
[ 2675 ]
1
[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]
[ 16, 13, 17 ]
3
true
Domain
Domain of unknown function DUF7792
Domain of unknown function DUF7792
DUF7792
1
IPR056695
56,695
Domain of unknown function DUF7793
DUF7793
Domain
1,060
false
false
This domain is found in uncharacterised bacterial proteins. A member from Arthrobacter sp. FB24 forms a swapped dimer ( ) in which one monomer exchanges a three-stranded β-sheet and an α-helix with the other monomer. The structure of this domain shares detectable similarity to SpoIIAA-like domains.
[]
[]
[]
0
[ "PFAM" ]
[ "PF25056" ]
[ "DUF7793" ]
[ 1060 ]
1
[]
[]
[]
0
[ "3bl4" ]
1
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria", "Candidatus Iainarchaeum sp.", "Haptolina ericina", "Marseillevirus LCMAC201", "metagenomes" ]
[ 1051, 1, 1, 1, 6 ]
5
[]
[]
0
true
Domain
Domain of unknown function DUF7793
Domain of unknown function DUF7793
DUF7793
9
IPR056696
56,696
Domain of unknown function DUF7794
DUF7794
Domain
951
false
false
This domain is found in uncharacterised plant proteins. It is predicted to fold into a globular structure with significant structural similarity to alkaline phosphatases.
[]
[]
[]
0
[ "PFAM" ]
[ "PF25070" ]
[ "DUF7794" ]
[ 951 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Viridiplantae" ]
[ 951 ]
1
[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]
[ 4, 3, 6 ]
3
true
Domain
Domain of unknown function DUF7794
Domain of unknown function DUF7794
DUF7794
7
IPR056697
56,697
Domain of unknown function DUF7795
DUF7795
Domain
727
false
false
This domain is fund in uncharacterised plant proteins. It is predicted to fold into alpha- helical bundle.
[]
[]
[]
0
[ "PFAM" ]
[ "PF25071" ]
[ "DUF7795" ]
[ 727 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Streptophyta" ]
[ 727 ]
1
[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]
[ 8, 8, 14 ]
3
true
Domain
Domain of unknown function DUF7795
Domain of unknown function DUF7795
DUF7795
9
IPR056698
56,698
Domain of unknown function DUF7796
DUF7796
Domain
941
false
false
This domain is found in uncharacterised proteins mainly from plants. It is predicted to adopt a globular alpha/ beta structure containing several disulfide bonds made by highly conserved cysteine residues.
[]
[]
[]
0
[ "PFAM" ]
[ "PF25072" ]
[ "DUF7796" ]
[ 941 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria", "Eukaryota", "Viruses", "viral metagenome" ]
[ 10, 922, 2, 7 ]
4
[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]
[ 5, 6, 5 ]
3
true
Domain
Domain of unknown function DUF7796
Domain of unknown function DUF7796
DUF7796
5
IPR056699
56,699
Domain of unknown function DUF7797
DUF7797
Domain
828
false
false
This domain is found in a group of uncharacterised plant proteins. This domain is often found associated with and is predicted to have an all-α helical configuration.
[]
[]
[]
0
[ "PFAM" ]
[ "PF25073" ]
[ "DUF7797" ]
[ 828 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Viridiplantae" ]
[ 828 ]
1
[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]
[ 16, 5, 7 ]
3
true
Domain
Domain of unknown function DUF7797
Domain of unknown function DUF7797
DUF7797
9
IPR056700
56,700
Domain of unknown function DUF7798
DUF7798
Domain
741
false
false
This domain is found in uncharacterised proteins mainly from plants. It is predicted to fold into an α-helical bundle.
[]
[]
[]
0
[ "PFAM" ]
[ "PF25074" ]
[ "DUF7798" ]
[ 741 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Eukaryota" ]
[ 741 ]
1
[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]
[ 8, 5, 9 ]
3
true
Domain
Domain of unknown function DUF7798
Domain of unknown function DUF7798
DUF7798
8
IPR056701
56,701
Repeat of unknown function DUF7799
DUF7799
Domain
327
false
false
This entry represents a presumed domain found towards the N-terminal of a group of uncharacterised sequences from C. elegans and related proteins from nematodes. This domain may consist of spectrin repeats.
[]
[]
[]
0
[ "PFAM" ]
[ "PF25075" ]
[ "DUF7799" ]
[ 327 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Eumetazoa" ]
[ 327 ]
1
[ "Caenorhabditis elegans" ]
[ 1 ]
1
true
Domain
Repeat of unknown function DUF7799
Repeat of unknown function DUF7799
DUF7799
5
IPR056702
56,702
Domain of unknown function DUF7800
DUF7800
Domain
2,431
false
false
This domain is found at the N-terminal end of a group of uncharacterised bacterial proteins that also contain . This domain is predicted to show an immunoglobulin-like fold.
[]
[]
[]
0
[ "PFAM" ]
[ "PF25077" ]
[ "DUF7800" ]
[ 2431 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria", "Candidatus Methanophaga sp. ANME-1 ERB7", "metagenomes" ]
[ 2411, 2, 18 ]
3
[]
[]
0
true
Domain
Domain of unknown function DUF7800
Domain of unknown function DUF7800
DUF7800
7
IPR056703
56,703
Domain of unknown function DUF7801
DUF7801
Domain
1,097
false
false
This domain is found in a group of uncharacterised fungal proteins. This domain is often found associated with and is predicted to show a helical configuration.
[]
[]
[]
0
[ "PFAM" ]
[ "PF25078" ]
[ "DUF7801" ]
[ 1097 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Eukaryota" ]
[ 1097 ]
1
[ "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)" ]
[ 1 ]
1
true
Domain
Domain of unknown function DUF7801
Domain of unknown function DUF7801
DUF7801
5
IPR056704
56,704
Domain of unknown function DUF7802
DUF7802
Domain
759
false
false
This domain is found in uncharacterised bacterial and eukaryotic proteins. It is predicted to contain nine transmembrane helices arranged in a bundle. This domain has similarity to domains members of the INSIG-like superfamily.
[]
[]
[]
0
[ "PFAM" ]
[ "PF25085" ]
[ "DUF7802" ]
[ 759 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria", "Eukaryota", "Methanosarcina acetivorans" ]
[ 117, 640, 2 ]
3
[ "Caenorhabditis elegans" ]
[ 1 ]
1
true
Domain
Domain of unknown function DUF7802
Domain of unknown function DUF7802
DUF7802
3
IPR056705
56,705
Domain of unknown function DUF7803
DUF7803
Domain
758
false
false
This domain is found in uncharacterised proteins mainly from plants. It is predicted to fold into four helices that form two helical hairpins arranged in V-shape.
[]
[]
[]
0
[ "PFAM", "PANTHER" ]
[ "PF25086", "PTHR36047" ]
[ "DUF7803", "" ]
[ 758, 716 ]
2
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Eukaryota" ]
[ 758 ]
1
[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]
[ 8, 6, 10 ]
3
true
Domain
Domain of unknown function DUF7803
Domain of unknown function DUF7803
DUF7803
2
IPR056706
56,706
Domain of unknown function DUF7804
DUF7804
Domain
720
false
false
This domain is found in uncharacterised plant proteins. It is predicted to fold into a globular structure consisting of a antiparallel β-sheet curved around a central α-helix.
[]
[]
[]
0
[ "PFAM" ]
[ "PF25089" ]
[ "DUF7804" ]
[ 720 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Viridiplantae" ]
[ 720 ]
1
[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]
[ 7, 4, 5 ]
3
true
Domain
Domain of unknown function DUF7804
Domain of unknown function DUF7804
DUF7804
7
IPR056707
56,707
Domain of unknown function DUF7805
DUF7805
Domain
952
false
false
This domain is found in a group of uncharacterised proteins from animals. Many proteins in this group also contain .
[]
[]
[]
0
[ "PFAM" ]
[ "PF25090" ]
[ "DUF7805" ]
[ 952 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Ecdysozoa" ]
[ 952 ]
1
[ "Drosophila melanogaster" ]
[ 6 ]
1
true
Domain
Domain of unknown function DUF7805
Domain of unknown function DUF7805
DUF7805
1
IPR056708
56,708
Domain of unknown function DUF7806
DUF7806
Domain
713
false
false
This domain is found in uncharacterised plant proteins. It is predicted to adopt a globular structure with similarity to members of the Kinetochore globular domain-like superfamily.
[]
[]
[]
0
[ "PFAM" ]
[ "PF25091" ]
[ "DUF7806" ]
[ 713 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Viridiplantae" ]
[ 713 ]
1
[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]
[ 4, 3, 10 ]
3
true
Domain
Domain of unknown function DUF7806
Domain of unknown function DUF7806
DUF7806
4
IPR056709
56,709
Protein of unknown function DUF7807
DUF7807
Family
224
false
false
This entry represents uncharacterised worm proteins. They are predicted to fold into two alpha-hairpins arranged in V-shape.
[]
[]
[]
0
[ "PFAM" ]
[ "PF25093" ]
[ "DUF7807" ]
[ 224 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Opisthokonta" ]
[ 224 ]
1
[ "Caenorhabditis elegans" ]
[ 4 ]
1
true
Family
Protein of unknown function DUF7807
Protein of unknown function DUF7807
DUF7807
7
IPR056710
56,710
Domain of unknown function DUF7808
DUF7808
Domain
672
false
false
This domain is found in Uncharacterized protein T05H10.3 from C.elegans and related nematode proteins. It is predicted to adopt a β-sandwich with similarity to domains members of H-lectin-like superfamily. This domain contains several highly conserved cysteine residues that are predicted to form disulfide bonds.
[]
[]
[]
0
[ "PFAM" ]
[ "PF25096" ]
[ "DUF7808" ]
[ 672 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Chromadorea" ]
[ 672 ]
1
[ "Caenorhabditis elegans" ]
[ 9 ]
1
true
Domain
Domain of unknown function DUF7808
Domain of unknown function DUF7808
DUF7808
1
IPR056711
56,711
Domain of unknown function DUF7809
DUF7809
Domain
514
false
false
This domain is found in a group of uncharacterised proteins from animals. It is predicted to adopt a mainly α-helical configuration.
[]
[]
[]
0
[ "PFAM" ]
[ "PF25100" ]
[ "DUF7809" ]
[ 514 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Caenorhabditis" ]
[ 514 ]
1
[ "Caenorhabditis elegans" ]
[ 11 ]
1
true
Domain
Domain of unknown function DUF7809
Domain of unknown function DUF7809
DUF7809
8
IPR056713
56,713
Domain of unknown function DUF7811
DUF7811
Domain
666
false
false
This domain is found in uncharacterised plant proteins. It is predicted to fold into a five-stranded antiparallel β-sheet and two α-helices packed on it.
[]
[]
[]
0
[ "PFAM" ]
[ "PF25103" ]
[ "DUF7811" ]
[ 666 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Viridiplantae" ]
[ 666 ]
1
[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]
[ 8, 4, 6 ]
3
true
Domain
Domain of unknown function DUF7811
Domain of unknown function DUF7811
DUF7811
8
IPR056714
56,714
Domain of unknown function DUF7812
DUF7812
Domain
670
false
false
This domain is found in uncharacterised plant proteins. It is predicted to fold into an α-helical structure with similarity to α-solenoid domains.
[]
[]
[]
0
[ "PFAM" ]
[ "PF25104" ]
[ "DUF7812" ]
[ 670 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Embryophyta" ]
[ 670 ]
1
[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]
[ 7, 3, 5 ]
3
true
Domain
Domain of unknown function DUF7812
Domain of unknown function DUF7812
DUF7812
3
IPR056715
56,715
Protein of unknown function DUF7813
DUF7813
Family
754
false
false
This entry represents uncharacterised proteins found in plants. They are predicted to adopt structures similar to choline-like transporters.
[]
[]
[]
0
[ "PFAM" ]
[ "PF25105" ]
[ "DUF7813" ]
[ 754 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Embryophyta" ]
[ 754 ]
1
[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]
[ 2, 3, 6 ]
3
true
Family
Protein of unknown function DUF7813
Protein of unknown function DUF7813
DUF7813
8
IPR056717
56,717
Domain of unknown function DUF7815
DUF7815
Domain
575
false
false
This domain is found in uncharacterised plant proteins. It contains two pairs of conserved cysteines that may be involved in metal coordination. It is predicted to adopt a structure typical for zinc ribbon domains.
[]
[]
[]
0
[ "PFAM" ]
[ "PF25122" ]
[ "DUF7815" ]
[ 575 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Tracheophyta" ]
[ 575 ]
1
[ "Arabidopsis thaliana", "Zea mays" ]
[ 16, 6 ]
2
true
Domain
Domain of unknown function DUF7815
Domain of unknown function DUF7815
DUF7815
8
IPR056718
56,718
NEDD4-binding protein 2, DUF7816
DUF7816
Domain
1,067
false
false
This domain is found towards the C terminus of human NEDD4-binding protein 2 (N4BP2), which has 5'-polynucleotide kinase and nicking endonuclease activity and may play a role in DNA repair or recombination [ ]. This domain is predicted to adopt an α configuration. Its specific function is unknown. It is normally found ...
[]
[]
[]
0
[ "PFAM" ]
[ "PF25124" ]
[ "DUF7816" ]
[ 1067 ]
1
[]
[]
[]
0
[]
0
[ "PUB00060369" ]
[ "12730195" ]
[ "Identification and characterization of BCL-3-binding protein: implications for transcription and DNA repair or recombination." ]
[ 2003 ]
1
[]
[]
0
0
null
[ "Bilateria" ]
[ 1067 ]
1
[ "Danio rerio", "Homo sapiens", "Mus musculus", "Rattus norvegicus" ]
[ 3, 3, 3, 5 ]
4
true
Domain
NEDD4-binding protein 2, DUF7816
NEDD4-binding protein 2, DUF7816
DUF7816
1
IPR056719
56,719
NEDD4-binding protein 2, DUF7817
DUF7817
Domain
1,009
false
false
This domain is found towards the C terminus of human NEDD4-binding protein 2 (N4BP2), which has 5'-polynucleotide kinase and nicking endonuclease activity and may play a role in DNA repair or recombination [ ]. This domain is often found N-terminal to and .
[]
[]
[]
0
[ "PFAM" ]
[ "PF25125" ]
[ "DUF7817" ]
[ 1009 ]
1
[]
[]
[]
0
[]
0
[ "PUB00060369" ]
[ "12730195" ]
[ "Identification and characterization of BCL-3-binding protein: implications for transcription and DNA repair or recombination." ]
[ 2003 ]
1
[]
[]
0
0
null
[ "Vertebrata" ]
[ 1009 ]
1
[ "Danio rerio", "Homo sapiens", "Mus musculus", "Rattus norvegicus" ]
[ 3, 3, 3, 5 ]
4
true
Domain
NEDD4-binding protein 2, DUF7817
NEDD4-binding protein 2, DUF7817
DUF7817
9
IPR056720
56,720
NEDD4-binding protein 2, DUF7818
DUF7818
Domain
1,280
false
false
This domain is found towards the C terminus of human NEDD4-binding protein 2 (N4BP2), which has 5'-polynucleotide kinase and nicking endonuclease activity and may play a role in DNA repair or recombination [ ]. This domain is often found associated with , and .
[]
[]
[]
0
[ "PFAM" ]
[ "PF25126" ]
[ "DUF7818" ]
[ 1280 ]
1
[]
[]
[]
0
[]
0
[ "PUB00060369" ]
[ "12730195" ]
[ "Identification and characterization of BCL-3-binding protein: implications for transcription and DNA repair or recombination." ]
[ 2003 ]
1
[]
[]
0
0
null
[ "Deuterostomia" ]
[ 1280 ]
1
[ "Danio rerio", "Homo sapiens", "Mus musculus", "Rattus norvegicus" ]
[ 3, 8, 3, 5 ]
4
true
Domain
NEDD4-binding protein 2, DUF7818
NEDD4-binding protein 2, DUF7818
DUF7818
2
IPR056721
56,721
Calcium homeostasis endoplasmic reticulum protein, DUF7819
DUF7819
Domain
2,192
false
false
This domain is found towards the C-terminal end of human Calcium homeostasis endoplasmic reticulum protein (CHERP), which is involved in calcium homeostasis, growth and proliferation [ , ]. This domain is usually found associated with . Its specific function is unknown. It shows highly conserved GWE and GLYE/DxY/F moti...
[]
[]
[]
0
[ "PFAM" ]
[ "PF25127" ]
[ "DUF7819" ]
[ 2192 ]
1
[ "REACTOME", "REACTOME" ]
[ "R-HSA-72163", "R-MMU-72163" ]
[ "REACTOME:R-HSA-72163", "REACTOME:R-MMU-72163" ]
2
[]
0
[ "PUB00088795", "PUB00159976" ]
[ "12656674", "10794731" ]
[ "Antisense-mediated loss of calcium homoeostasis endoplasmic reticulum protein (CHERP; ERPROT213-21) impairs Ca2+ mobilization, nuclear factor of activated T-cells (NFAT) activation and cell proliferation in Jurkat T-lymphocytes.", "Cloning of human Ca2+ homoeostasis endoplasmic reticulum protein (CHERP): regulat...
[ 2003, 2000 ]
2
[]
[]
0
0
null
[ "Opisthokonta" ]
[ 2192 ]
1
[ "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Homo sapiens", "Mus musculus", "Rattus norvegicus" ]
[ 1, 5, 3, 5, 3, 3 ]
6
true
Domain
Calcium homeostasis endoplasmic reticulum protein, DUF7819
Calcium homeostasis endoplasmic reticulum protein, DUF7819
DUF7819
2
IPR056722
56,722
Domain of unknown function DUF7820
DUF7820
Domain
1,073
false
false
This domain is found in uncharacterised proteins from fungi. It contains three pairs of conserved cysteine residues that are predicted to form disulfide bonds. It also contains a long region that is predicted to be disordered.
[]
[]
[]
0
[ "PFAM" ]
[ "PF25130" ]
[ "DUF7820" ]
[ 1073 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Eukaryota" ]
[ 1073 ]
1
[ "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)" ]
[ 1 ]
1
true
Domain
Domain of unknown function DUF7820
Domain of unknown function DUF7820
DUF7820
9
IPR056723
56,723
Domain of unknown function DUF7821
DUF7821
Domain
123
false
false
This domain is found N-terminal in the uncharacterised protein PM0657 and its paralogue PM1082 from Pasteurella multocida and related bacterial proteins. It is predicted to adopt a α/β globular structure consisting of a central antiparallel β-sheet and helices packed on both sides.
[]
[]
[]
0
[ "PFAM" ]
[ "PF25134" ]
[ "DUF7821" ]
[ 123 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Pseudomonadati" ]
[ 123 ]
1
[]
[]
0
true
Domain
Domain of unknown function DUF7821
Domain of unknown function DUF7821
DUF7821
8
IPR056724
56,724
Domain of unknown function DUF7822
DUF7822
Domain
309
false
false
This domain is found N-terminal in uncharacterised bacterial proteins. It is predicted to adopt a globular structure consisting of a curved β-sheet and α-helices packed on one side of it.
[]
[]
[]
0
[ "PFAM" ]
[ "PF25135" ]
[ "DUF7822" ]
[ 309 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria" ]
[ 309 ]
1
[]
[]
0
true
Domain
Domain of unknown function DUF7822
Domain of unknown function DUF7822
DUF7822
2
IPR056725
56,725
Domain of unknown function DUF7823
DUF7823
Domain
203
false
false
This domain is found in uncharacterised proteins from Gammaproteobacteria. This domain is found usually associated with .
[]
[]
[]
0
[ "PFAM" ]
[ "PF25136" ]
[ "DUF7823" ]
[ 203 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Enterobacterales" ]
[ 203 ]
1
[]
[]
0
true
Domain
Domain of unknown function DUF7823
Domain of unknown function DUF7823
DUF7823
5
IPR056726
56,726
Repeat of unknown function DUF7824
DUF7824
Domain
1,101
false
false
This is a presumed domain found in the middle region of bacterial sequences, which have a at the N-terminal.
[]
[]
[]
0
[ "PFAM" ]
[ "PF25148" ]
[ "DUF7824" ]
[ 1101 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria", "Tanacetum cinerariifolium" ]
[ 1098, 3 ]
2
[]
[]
0
true
Domain
Repeat of unknown function DUF7824
Repeat of unknown function DUF7824
DUF7824
5
IPR056727
56,727
Repeat of unknown function DUF7825
DUF7825
Domain
687
false
false
This is a presumed domain found at the C-terminal of a group of uncharacterised sequences from bacteria. It may adopt a TPR-like fold. It is found associated with at the N-terminal and in the middle.
[]
[]
[]
0
[ "PFAM" ]
[ "PF25149" ]
[ "DUF7825" ]
[ 687 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria", "Tanacetum cinerariifolium", "marine sediment metagenome" ]
[ 685, 1, 1 ]
3
[]
[]
0
true
Domain
Repeat of unknown function DUF7825
Repeat of unknown function DUF7825
DUF7825
7
IPR056728
56,728
Iron export permease protein FetB
FetB
Family
889
false
false
This entry includes the probable iron export permease protein FetB from Escherichia coli and similar proteins specific to gammaproteobacteria. FetB (Fe Transport B) is one subunit of the iron efflux ABC transporter FetAB. FetA is the ATP-binding subunit and FetB is the permease subunit. FetB is thought to be responsibl...
[]
[]
[]
0
[ "NCBIFAM" ]
[ "TIGR00245" ]
[ "" ]
[ 889 ]
1
[]
[]
[]
0
[]
0
[ "PUB00070818" ]
[ "24038693" ]
[ "Overexpression of fetA (ybbL) and fetB (ybbM), Encoding an Iron Exporter, Enhances Resistance to Oxidative Stress in Escherichia coli." ]
[ 2013 ]
1
[ "IPR005226" ]
[]
1
0
1
[ "Enterobacterales" ]
[ 889 ]
1
[ "Escherichia coli (strain K12)" ]
[ 1 ]
1
true
Family
Iron export permease protein FetB
Iron export permease protein FetB
FetB
9
IPR056729
56,729
Mannose-1-phosphate guanyltransferase, C-terminal domain
GMPPB_C
Domain
29,432
false
false
This entry represents the C-terminal domain of Mannose-1-phosphate guanyltransferase MPG1 from fungi [ ] and Mannose-1-phosphate guanylyltransferase catalytic subunits alpha and beta (GMPPA/B) from animals. This domain consists of a left-handed parallel β-helix composed of tandem repeats of a [LIV]-G-X(4) hexapeptide [...
[]
[]
[]
0
[ "PFAM" ]
[ "PF25087" ]
[ "GMPPB_C" ]
[ 29432 ]
1
[ "EC", "EC", "EC", "METACYC", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME" ]
[ "2.3.1", "2.3.1.157", "2.7.7.23", "PWY-5514", "R-CEL-446205", "R-DDI-446205", "R-DME-446205", "R-DRE-446205", "R-HSA-446205", "R-MMU-446205", "R-RNO-446205", "R-SCE-72731", "R-SPO-446205", "R-XTR-446205" ]
[ "EC:2.3.1", "EC:2.3.1.157", "EC:2.7.7.23", "METACYC:PWY-5514", "REACTOME:R-CEL-446205", "REACTOME:R-DDI-446205", "REACTOME:R-DME-446205", "REACTOME:R-DRE-446205", "REACTOME:R-HSA-446205", "REACTOME:R-MMU-446205", "REACTOME:R-RNO-446205", "REACTOME:R-SCE-72731", "REACTOME:R-SPO-446205", "RE...
14
[ "1fwy", "1fxj", "1hv9", "2ggo", "2ggq", "2oi5", "2oi6", "2oi7", "2v0h", "2v0i", "2v0j", "2v0k", "2v0l", "2vd4", "2w0v", "2w0w", "3fww", "3twd", "4aa7", "4e1k", "4e75", "4e79", "4fce", "4knr", "4knx", "4kpx", "4kpz", "4kql", "5vmk", "5z09", "5z0a", "6i3m"...
50
[ "PUB00098328", "PUB00098329", "PUB00155047", "PUB00155048" ]
[ "11055399", "16049679", "24035193", "33986552" ]
[ "Defect in cell wall integrity of the yeast saccharomyces cerevisiae caused by a mutation of the GDP-mannose pyrophosphorylase gene VIG9.", "Mpg1, a fission yeast protein required for proper septum structure, is involved in cell cycle progression through cell-size checkpoint.", "Mutations in GMPPA cause a glyco...
[ 2000, 2005, 2013, 2021 ]
4
[]
[]
0
0
null
[ "Archaea", "Bacteria", "Caudoviricetes", "Eukaryota", "unclassified sequences" ]
[ 1888, 16596, 5, 10537, 406 ]
5
[ "Arabidopsis thaliana", "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Escherichia coli (strain K12)", "Homo sapiens", "Mus musculus", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Oryza sativa subsp. japonica", "Rattus norvegicus",...
[ 22, 3, 15, 8, 2, 8, 3, 2, 8, 4, 2, 2, 39 ]
13
true
Domain
Mannose-1-phosphate guanyltransferase, C-terminal domain
Mannose-1-phosphate guanyltransferase, C-terminal domain
GMPPB_C
8
IPR056730
56,730
DUF2096, C-terminal KH-like domain
DUF2096_C
Domain
84
false
false
This domain, found in various hypothetical archaeal proteins, has no known function. Many members belong to . The domain shows structural similarity to KH domains suggesting it may have an RNA-binding function.
[]
[]
[]
0
[ "PFAM" ]
[ "PF09869" ]
[ "KH_DUF2096_C" ]
[ 84 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Methanomada group", "bioreactor metagenome" ]
[ 83, 1 ]
2
[]
[]
0
true
Domain
DUF2096, C-terminal KH-like domain
DUF2096, C-terminal KH-like domain
DUF2096_C
3
IPR056731
56,731
DUF2096, N-terminal four-helical bundle domain
DUF2096_N
Domain
87
false
false
This domain, found in various hypothetical archaeal proteins, has no known function. Many members belong to . This N-terminal domain is predicted to be composed of four α helices.
[]
[]
[]
0
[ "PFAM" ]
[ "PF23100" ]
[ "DUF2096_N" ]
[ 87 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Archaea", "bioreactor metagenome" ]
[ 86, 1 ]
2
[]
[]
0
true
Domain
DUF2096, N-terminal four-helical bundle domain
DUF2096, N-terminal four-helical bundle domain
DUF2096_N
7
IPR056732
56,732
Attractin, GBD domain
GBD_ATRN
Domain
3,703
false
false
This entry represents a domain found towards the C terminus of attractin (ATRN) and attractin-like proteins. ATRN is involved in the initial immune cell clustering during inflammatory response and may regulate chemotactic activity of chemokines. It may play a role in melanocortin signalling pathways that regulate energ...
[]
[]
[]
0
[ "PFAM" ]
[ "PF24972" ]
[ "GBD_ATRN" ]
[ 3703 ]
1
[]
[]
[]
0
[]
0
[ "PUB00082152", "PUB00155414" ]
[ "9736737", "17261078" ]
[ "Attractin (DPPT-L), a member of the CUB family of cell adhesion and guidance proteins, is secreted by activated human T lymphocytes and modulates immune cell interactions.", "Does human attractin have DP4 activity?" ]
[ 1998, 2007 ]
2
[]
[]
0
0
null
[ "Eumetazoa" ]
[ 3703 ]
1
[ "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Homo sapiens", "Mus musculus", "Rattus norvegicus" ]
[ 1, 8, 4, 5, 4, 9 ]
6
true
Domain
Attractin, GBD domain
Attractin, GBD domain
GBD_ATRN
1
IPR056734
56,734
N-acetylneuraminate epimerase
NANM
Family
2,849
false
false
This entry includes N-acetylneuraminate epimerase (NANM) from Haemophilus influenzae, E. coli and its homologues. It converts alpha-N-acetylneuranimic acid (Neu5Ac) to the β-anomer, accelerating the equilibrium between the α- and β-anomers [ , ]. The structure of NANM comprises a dimeric 6-bladed unclosed β-propeller .
[]
[]
[]
0
[ "PFAM" ]
[ "PF24996" ]
[ "NANM" ]
[ 2849 ]
1
[ "EC" ]
[ "5.1.3.24" ]
[ "EC:5.1.3.24" ]
1
[ "2uvk" ]
1
[ "PUB00045883", "PUB00099659" ]
[ "18063573", "33895133" ]
[ "Sialic acid mutarotation is catalyzed by the Escherichia coli beta-propeller protein YjhT.", "The metalloprotein YhcH is an anomerase providing N-acetylneuraminate aldolase with the open form of its substrate." ]
[ 2008, 2021 ]
2
[]
[ "IPR019936" ]
0
1
0
[ "Bacteria", "Eukaryota", "unclassified sequences" ]
[ 2811, 11, 27 ]
3
[ "Escherichia coli (strain K12)" ]
[ 1 ]
1
true
Family
N-acetylneuraminate epimerase
N-acetylneuraminate epimerase
NANM
7
IPR056735
56,735
Sucrose synthase, N-terminal
SUS_N
Domain
4,407
false
false
This entry represents the N-terminal domain of sucrose synthases, which corresponds to the cellular targeting domain (CTD, also referred to as SSN1) and together with the EPBD domain (SSN2, ), they have regulatory functions in plant species, however, the function of these domains in cyanobacteria is not yet clear [ , ]...
[]
[]
[]
0
[ "PFAM" ]
[ "PF24861" ]
[ "SUS_N" ]
[ 4407 ]
1
[ "EC", "METACYC" ]
[ "2.4.1.13", "PWY-3801" ]
[ "EC:2.4.1.13", "METACYC:PWY-3801" ]
2
[ "3s27", "3s28", "3s29", "4rbn" ]
4
[ "PUB00057019", "PUB00159903" ]
[ "21865170", "26013491" ]
[ "The structure of sucrose synthase-1 from Arabidopsis thaliana and its functional implications.", "The Crystal Structure of Nitrosomonas europaea Sucrose Synthase Reveals Critical Conformational Changes and Insights into Sucrose Metabolism in Prokaryotes." ]
[ 2011, 2015 ]
2
[]
[]
0
0
null
[ "Bacteria", "Viridiplantae", "ecological metagenomes" ]
[ 343, 4059, 5 ]
3
[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]
[ 35, 16, 52 ]
3
true
Domain
Sucrose synthase, N-terminal
Sucrose synthase, N-terminal
SUS_N
4
IPR056736
56,736
Sucrose synthase, EPBD domain
SUS_EPBD
Domain
4,461
false
false
This entry represents the EPBD domain (ENOD40 peptide binding domain, also referred to as SSN2) of sucrose synthases, which corresponds to the second domain and together with the N-terminal one ( ), referred to as the cellular targeting domain (CTD) have regulatory functions in plant species, however, the function of t...
[]
[]
[]
0
[ "PFAM" ]
[ "PF24862" ]
[ "SUS_EPBD" ]
[ 4461 ]
1
[ "EC", "METACYC" ]
[ "2.4.1.13", "PWY-3801" ]
[ "EC:2.4.1.13", "METACYC:PWY-3801" ]
2
[ "3s27", "3s28", "3s29", "4rbn" ]
4
[ "PUB00057019", "PUB00159903" ]
[ "21865170", "26013491" ]
[ "The structure of sucrose synthase-1 from Arabidopsis thaliana and its functional implications.", "The Crystal Structure of Nitrosomonas europaea Sucrose Synthase Reveals Critical Conformational Changes and Insights into Sucrose Metabolism in Prokaryotes." ]
[ 2011, 2015 ]
2
[]
[]
0
0
null
[ "Bacteria", "Viridiplantae", "ecological metagenomes" ]
[ 384, 4070, 7 ]
3
[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]
[ 36, 16, 51 ]
3
true
Domain
Sucrose synthase, EPBD domain
Sucrose synthase, EPBD domain
SUS_EPBD
6
IPR056738
56,738
NfeD1b, N-terminal domain
NfeD1b_N
Domain
5,125
false
false
This domain is found N-terminal in the membrane protein NfeD1b from B. subtilis and related bacterial proteins. The NfeD1b is composed of an N-terminal cytoplasmic ClpP serine protease-like domain, transmembrane domain, and a C-terminal OB (oligosaccharide/oligonucleotide-binding) fold domain. NfeD1b is a member of the...
[]
[]
[]
0
[ "PFAM" ]
[ "PF25145" ]
[ "NfeD1b_N" ]
[ 5125 ]
1
[]
[]
[]
0
[ "2deo", "3bpp", "3viv", "3wg5", "6m4b" ]
5
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Archaea", "Bacteria", "Eukaryota", "unclassified sequences" ]
[ 264, 4722, 6, 133 ]
4
[]
[]
0
true
Domain
NfeD1b, N-terminal domain
NfeD1b, N-terminal domain
NfeD1b_N
7
IPR056739
56,739
NfeD, integral membrane domain
NfeD_membrane
Domain
6,490
false
false
This entry represents the central integral membrane domain found in the NfeD protein and related proteins. The NfeD1b is composed of an N-terminal cytoplasmic ClpP serine protease-like domain, transmembrane domain, and a C-terminal OB (oligosaccharide/oligonucleotide-binding) fold domain. NfeD1b is a member of the NfeD...
[]
[]
[]
0
[ "PFAM" ]
[ "PF24961" ]
[ "NfeD_membrane" ]
[ 6490 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Archaea", "Bacteria", "Eukaryota", "unclassified sequences" ]
[ 260, 6009, 6, 215 ]
4
[]
[]
0
true
Domain
NfeD, integral membrane domain
NfeD, integral membrane domain
NfeD_membrane
9
IPR056740
56,740
Dihydroxy-acid/6-phosphogluconate dehydratase, C-terminal
ILV_EDD_C
Domain
54,302
false
false
This is the C-terminal domain of Ilv/ED dehydratase protein family which includes dihydroxy-acid/6-phosphogluconate dehydratases, and pentonate dehydratases [ ]. This domain is composed of a β-sheet consisting of six parallel and two anti-parallel β-strands that are arranged like a β-barrel [ , ]. Members of this entry...
[]
[]
[]
0
[ "PFAM" ]
[ "PF24877" ]
[ "ILV_EDD_C" ]
[ 54302 ]
1
[ "EC", "EC", "METACYC", "METACYC", "METACYC", "METACYC" ]
[ "4.2.1", "4.2.1.9", "PWY-5101", "PWY-5103", "PWY-5104", "PWY-7111" ]
[ "EC:4.2.1", "EC:4.2.1.9", "METACYC:PWY-5101", "METACYC:PWY-5103", "METACYC:PWY-5104", "METACYC:PWY-7111" ]
6
[ "2gp4", "5j83", "5j84", "5j85", "5oyn", "5ym0", "5ze4", "6nte", "6ovt", "7m3k", "8ej0", "8epz", "8hs0", "8ikz", "8imu", "9evv", "9ix7", "9jpi", "9jsq", "9l8r" ]
20
[ "PUB00002191", "PUB00159907", "PUB00159908" ]
[ "1624451", "29339766", "28574691" ]
[ "Molecular characterization of the Entner-Doudoroff pathway in Escherichia coli: sequence analysis and localization of promoters for the edd-eda operon.", "The crystal structure of D-xylonate dehydratase reveals functional features of enzymes from the Ilv/ED dehydratase family.", "The Crystal Structure of a Bac...
[ 1992, 2018, 2017 ]
3
[]
[]
0
0
null
[ "Archaea", "Bacteria", "Eukaryota", "unclassified Caudoviricetes", "unclassified sequences" ]
[ 861, 46773, 5825, 2, 841 ]
5
[ "Arabidopsis thaliana", "Escherichia coli (strain K12)", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Oryza sativa subsp. japonica", "Saccharomyces cerevisiae (strain ATCC 204508 / S288c)", "Schizosaccharomyces pombe (strain 972 / ATCC 24843)", "Zea mays" ]
[ 3, 4, 2, 2, 1, 1, 10 ]
7
true
Domain
Dihydroxy-acid/6-phosphogluconate dehydratase, C-terminal
Dihydroxy-acid/6-phosphogluconate dehydratase, C-terminal
ILV_EDD_C
8
IPR056741
56,741
Bridge-like lipid transfer protein family member 1, middle region
BLTP1_M
Domain
2,660
false
false
This entry represents the middle region of a group of very long animal proteins, including human BLTP1. Bridge-like lipid transfer protein family member 1 (BLTP1, formerly known as Tweek/KIAA1109/FSA in human) is a tube-forming lipid transport protein which provides phosphatidylethanolamine for glycosylphosphatidylinos...
[]
[]
[]
0
[ "PFAM" ]
[ "PF25039" ]
[ "BLTP1_M" ]
[ 2660 ]
1
[]
[]
[]
0
[ "9cap" ]
1
[ "PUB00079303", "PUB00079304", "PUB00090168", "PUB00101861", "PUB00101862", "PUB00101871", "PUB00101872" ]
[ "26917059", "20553587", "29290337", "35491307", "35015055", "31540829", "30906834" ]
[ "Association of rs6822844 within the KIAA1109/TENR/IL2/IL21 locus with rheumatoid arthritis in the Algerian population.", "Only one independent genetic association with rheumatoid arthritis within the KIAA1109-TENR-IL2-IL21 locus in Caucasian sample sets: confirmation of association of rs6822844 with rheumatoid a...
[ 2016, 2010, 2018, 2022, 2022, 2019, 2019 ]
7
[]
[]
0
0
null
[ "Eumetazoa" ]
[ 2660 ]
1
[ "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Homo sapiens", "Mus musculus", "Rattus norvegicus" ]
[ 4, 52, 6, 8, 2, 7 ]
6
true
Domain
Bridge-like lipid transfer protein family member 1, middle region
Bridge-like lipid transfer protein family member 1, middle region
BLTP1_M
6
IPR056743
56,743
TRM5/TYW2-like, methyltransferase domain
TRM5-TYW2-like_MTfase
Domain
10,235
false
false
This is the methyltransferase domain of TRM5/TYW2 proteins, SAM-dependent methyltransferases that are involved in tRNA methylation [ ]. Members are found in all cellular organisms.
[]
[]
[]
0
[ "PFAM" ]
[ "PF02475" ]
[ "TRM5-TYW2_MTfase" ]
[ 10235 ]
1
[ "EC", "METACYC", "METACYC", "METACYC", "REACTOME" ]
[ "2.1.1.228", "PWY-6829", "PWY-7285", "PWY-7286", "R-HSA-6782861" ]
[ "EC:2.1.1.228", "METACYC:PWY-6829", "METACYC:PWY-7285", "METACYC:PWY-7286", "REACTOME:R-HSA-6782861" ]
5
[ "2yx1", "2zzm", "2zzn", "3a25", "3a26", "3a27", "3ay0", "3k6r", "5hji", "5hjj", "5hjk", "5hjm", "5wt1", "5wt3", "5yac" ]
15
[ "PUB00009505", "PUB00058054" ]
[ "7557397", "20382657" ]
[ "Sequence of the met-10+ locus of Neurospora crassa: homology to a sequence of unknown function in Saccharomyces cerevisiae chromosome 8.", "Biosynthesis of wyosine derivatives in tRNA: an ancient and highly diverse pathway in Archaea." ]
[ 1995, 2010 ]
2
[]
[]
0
0
null
[ "Archaea", "Bacteria", "Eukaryota", "metagenomes" ]
[ 1750, 472, 7916, 97 ]
4
[ "Arabidopsis thaliana", "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Homo sapiens", "Mus musculus", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Oryza sativa subsp. japonica", "Rattus norvegicus", "Saccharomyces cerevisiae (strai...
[ 14, 2, 3, 1, 2, 2, 1, 6, 6, 2, 2, 28 ]
12
true
Domain
TRM5/TYW2-like, methyltransferase domain
TRM5/TYW2-like, methyltransferase domain
TRM5-TYW2-like_MTfase
5
IPR056744
56,744
TRM5/TYW2-like, N-terminal domain
TRM5/TYW2-like_N
Domain
8,308
false
false
This is the N-terminal domain of of TRM5/TYW2 proteins, SAM-dependent methyltransferases that are involved in tRNA methylation [ ] and related sequences found in archaea and eukaryotes [ ]. This domain consists of six β-strands and three α-helices.
[]
[]
[]
0
[ "PFAM" ]
[ "PF25133" ]
[ "TYW2_N_2" ]
[ 8308 ]
1
[ "EC", "METACYC", "METACYC", "METACYC", "REACTOME" ]
[ "2.1.1.228", "PWY-6829", "PWY-7285", "PWY-7286", "R-HSA-6782861" ]
[ "EC:2.1.1.228", "METACYC:PWY-6829", "METACYC:PWY-7285", "METACYC:PWY-7286", "REACTOME:R-HSA-6782861" ]
5
[ "2yx1", "2zzm", "2zzn", "3a25", "3a26", "3a27", "3ay0", "3k6r", "5hji", "5hjj", "5hjk", "5hjm", "5wt1", "5wt3", "5yac" ]
15
[ "PUB00052807", "PUB00058054" ]
[ "19717466", "20382657" ]
[ "Structural basis of AdoMet-dependent aminocarboxypropyl transfer reaction catalyzed by tRNA-wybutosine synthesizing enzyme, TYW2.", "Biosynthesis of wyosine derivatives in tRNA: an ancient and highly diverse pathway in Archaea." ]
[ 2009, 2010 ]
2
[]
[]
0
0
null
[ "Archaea", "Bacteria", "Eukaryota", "ecological metagenomes" ]
[ 1395, 13, 6840, 60 ]
4
[ "Arabidopsis thaliana", "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Homo sapiens", "Mus musculus", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Oryza sativa subsp. japonica", "Rattus norvegicus", "Saccharomyces cerevisiae (strai...
[ 15, 2, 2, 1, 2, 2, 1, 5, 6, 1, 1, 30 ]
12
true
Domain
TRM5/TYW2-like, N-terminal domain
TRM5/TYW2-like, N-terminal domain
TRM5/TYW2-like_N
3
IPR056745
56,745
TYW2, N-terminal domain
TYW2_N
Domain
703
false
false
This entry represents the N-terminal domain of tRNA wybutosine-synthesizing protein 2 homolog (TWY2) and similar sequences from vertebrates. TWY2 is a SAM-dependent transferase that acts as a component of the wybutosine biosynthesis pathway [ ]. This domain may consist of three β-sheets and two α-helices.
[]
[]
[]
0
[ "PFAM" ]
[ "PF25132" ]
[ "TYW2_N" ]
[ 703 ]
1
[ "EC", "METACYC", "REACTOME" ]
[ "2.5.1.114", "PWY-7286", "R-HSA-6782861" ]
[ "EC:2.5.1.114", "METACYC:PWY-7286", "REACTOME:R-HSA-6782861" ]
3
[]
0
[ "PUB00159942" ]
[ "22761755" ]
[ "Structure-function analysis of human TYW2 enzyme required for the biosynthesis of a highly modified Wybutosine (yW) base in phenylalanine-tRNA." ]
[ 2012 ]
1
[]
[]
0
0
null
[ "Eukaryota" ]
[ 703 ]
1
[ "Danio rerio", "Homo sapiens", "Mus musculus", "Rattus norvegicus" ]
[ 1, 2, 1, 2 ]
4
true
Domain
TYW2, N-terminal domain
TYW2, N-terminal domain
TYW2_N
2
IPR056746
56,746
Surface presentation of antigen domain
SPAN_dom
Domain
864
false
false
Surface presentation of antigens protein (SPAN), also know as invasion protein invJ, is a Salmonella secretory pathway protein involved in presentation of determinants required for mammalian host cell invasion. This entry represents a C-terminal domain found in these proteins. This domain is predicted to be composed of...
[]
[]
[]
0
[ "PFAM" ]
[ "PF02510" ]
[ "SPAN" ]
[ 864 ]
1
[]
[]
[]
0
[]
0
[ "PUB00005977" ]
[ "7752894" ]
[ "Functional analysis of the Salmonella typhimurium invasion genes invl and invJ and identification of a target of the protein secretion apparatus encoded in the inv locus." ]
[ 1995 ]
1
[]
[]
0
0
null
[ "Pseudomonadati", "human gut metagenome" ]
[ 862, 2 ]
2
[]
[]
0
true
Domain
Surface presentation of antigen domain
Surface presentation of antigen domain
SPAN_dom
2
IPR056747
56,747
VPS13-like, middle region
VPS13-like_M
Domain
9,225
false
false
This entry represents the middle region of the VPS13 proteins. VPS13 proteins have been implicated in processes including vesicle fusion, autophagy, and actin regulation. They bind phospholipids and act as channels that mediate the transfer of lipids between membranes at organelle contact sites [ , , , ]. It has been p...
[]
[]
[]
0
[ "PFAM" ]
[ "PF25033" ]
[ "VPS13_M" ]
[ 9225 ]
1
[]
[]
[]
0
[]
0
[ "PUB00062177", "PUB00100501", "PUB00100726", "PUB00100766", "PUB00100863" ]
[ "17196930", "30018089", "34830155", "30741634", "34216812" ]
[ "Brain-specific transcript variants of 5' and 3' ends of mouse VPS13A and VPS13C.", "Competitive organelle-specific adaptors recruit Vps13 to membrane contact sites.", "The GTPase Arf1 Is a Determinant of Yeast Vps13 Localization to the Golgi Apparatus.", "Human VPS13A is associated with multiple organelles a...
[ 2007, 2018, 2021, 2019, 2021 ]
5
[]
[]
0
0
null
[ "Eukaryota" ]
[ 9225 ]
1
[ "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Homo sapiens", "Mus musculus", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Rattus norvegicus", "Schizosaccharomyces pombe (strain 972 / ATCC 24843)", "Zea mays" ]
[ 2, 39, 2, 14, 9, 1, 28, 2, 4 ]
9
true
Domain
VPS13-like, middle region
VPS13-like, middle region
VPS13-like_M
6
IPR056748
56,748
Intermembrane lipid transfer protein VPS13-like, C-terminal
VPS13-like_C
Domain
9,082
false
false
This entry represents the C-terminal PH-like domain from VPS13 which weakly binds to phosphatidylinositol 4,5-bisphosphate and contributes to membrane recruitment [ , , ]. Truncation of this domain in VPS13A are causative for chorea-acanthocytosis, which suggests that it plays an important function [ ]. VPS13 proteins ...
[]
[]
[]
0
[ "PFAM" ]
[ "PF25037" ]
[ "VPS13_C" ]
[ 9082 ]
1
[]
[]
[]
0
[]
0
[ "PUB00062177", "PUB00100501", "PUB00100726", "PUB00100766", "PUB00100769", "PUB00100863", "PUB00101955" ]
[ "17196930", "30018089", "34830155", "30741634", "30093493", "34216812", "33809364" ]
[ "Brain-specific transcript variants of 5' and 3' ends of mouse VPS13A and VPS13C.", "Competitive organelle-specific adaptors recruit Vps13 to membrane contact sites.", "The GTPase Arf1 Is a Determinant of Yeast Vps13 Localization to the Golgi Apparatus.", "Human VPS13A is associated with multiple organelles a...
[ 2007, 2018, 2021, 2019, 2018, 2021, 2021 ]
7
[]
[]
0
0
null
[ "Eukaryota", "Janibacter alkaliphilus" ]
[ 9081, 1 ]
2
[ "Arabidopsis thaliana", "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Homo sapiens", "Mus musculus", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Oryza sativa subsp. japonica", "Rattus norvegicus", "Saccharomyces cerevisiae (strai...
[ 33, 2, 22, 1, 9, 16, 1, 10, 15, 1, 2, 30 ]
12
true
Domain
Intermembrane lipid transfer protein VPS13-like, C-terminal
Intermembrane lipid transfer protein VPS13-like, C-terminal
VPS13-like_C
9