interpro_id string | interpro_numeric_id int64 | name string | short_name string | entry_type string | protein_count int64 | is_llm bool | is_llm_reviewed bool | abstract string | go_ids list | go_terms list | go_categories list | go_count int64 | member_databases list | member_accessions list | member_names list | member_protein_counts list | member_count int64 | external_databases list | external_accessions list | external_xrefs list | external_xref_count int64 | pdb_ids list | structure_count int64 | publication_ids list | pubmed_ids list | publication_titles list | publication_years list | publication_count int64 | parent_ids list | child_ids list | parent_count int64 | child_count int64 | tree_depth float64 | taxonomy_names list | taxonomy_protein_counts list | taxonomy_count int64 | key_species_names list | key_species_protein_counts list | key_species_count int64 | in_entry_list bool | entry_list_type string | entry_list_name string | names_dat_name string | short_names_dat_name string | split_bucket int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
IPR059332 | 59,332 | Domain of unknown function DUF8288 | DUF8288 | Domain | 34 | false | false | This domain is found in uncharacterised proteins mainly from Saprolegniales lineage. It contains several conserved cysteine residues which are predicted to form disulfide bonds. This domain is frequently found in combination with . | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF26937"
] | [
"DUF8288"
] | [
34
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Saprolegniales"
] | [
34
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8288 | Domain of unknown function DUF8288 | DUF8288 | 8 |
IPR059334 | 59,334 | Domain of unknown function DUF8290 | DUF8290 | Domain | 166 | false | false | This entry represents a domain found mainly in Flavobacteriales lineage. It is predicted to fold into a small β-sandwich elaborated with long loops. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF26939"
] | [
"DUF8290"
] | [
166
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Weeksellaceae"
] | [
166
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8290 | Domain of unknown function DUF8290 | DUF8290 | 5 |
IPR059335 | 59,335 | Domain of unknown function DUF8291 | DUF8291 | Domain | 34 | false | false | This domain is found in uncharacterised bacterial proteins. Many members contain cysteine residues which are predicted to for disulfide bond. This domain is frequently found in tandem copies. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF26940"
] | [
"DUF8291"
] | [
34
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Cytophagales"
] | [
34
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8291 | Domain of unknown function DUF8291 | DUF8291 | 6 |
IPR059336 | 59,336 | Domain of unknown function DUF8292 | DUF8292 | Domain | 523 | false | false | This entry represents a domain of unknown function in a group of proteins mainly from animals. This domain contains a tetraspanin-like fold which consists of an array of α-helices. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF26941"
] | [
"DUF8292"
] | [
523
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Mimiviridae sp. ChoanoV1",
"metagenomes"
] | [
38,
480,
1,
4
] | 4 | [
"Caenorhabditis elegans"
] | [
3
] | 1 | true | Domain | Domain of unknown function DUF8292 | Domain of unknown function DUF8292 | DUF8292 | 7 |
IPR059337 | 59,337 | Domain of unknown function DUF8293 | DUF8293 | Domain | 1,614 | false | false | This domain is found in uncharacterised bacterial proteins. It is predicted to fold into an α-helical structure and it is frequently found in combination with and and which are likely involved in pilus biogenesis. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF26942"
] | [
"DUF8293"
] | [
1614
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Rhabditida",
"ecological metagenomes"
] | [
1609,
2,
3
] | 3 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8293 | Domain of unknown function DUF8293 | DUF8293 | 6 |
IPR059338 | 59,338 | Domain of unknown function DUF8294 | DUF8294 | Domain | 13 | false | false | This domain is found in uncharacterised proteins mainly from Desulfobacterales. It is predicted to fold into an open barrel structure decorated with α-helices. It contains a conserved DGRxF sequence motif which may be important for function. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF26943"
] | [
"DUF8294"
] | [
13
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Owenia fusiformis"
] | [
12,
1
] | 2 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8294 | Domain of unknown function DUF8294 | DUF8294 | 5 |
IPR059339 | 59,339 | Domain of unknown function DUF8295 | DUF8295 | Domain | 144 | false | false | This domain is found in uncharacterised proteins mainly from Spirochaetia lineage. It is predicted to fold into a complex α/β structure resembling open β-barrel decorated with α helices. | [] | [] | [] | 0 | [
"NCBIFAM",
"PFAM"
] | [
"NF047504",
"PF26945"
] | [
"LIC_10030_fam",
"DUF8295"
] | [
125,
144
] | 2 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Spirochaetia"
] | [
144
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8295 | Domain of unknown function DUF8295 | DUF8295 | 3 |
IPR059340 | 59,340 | Domain of unknown function DUF8296 | DUF8296 | Domain | 46 | false | false | This domain is found in uncharacterised proteins. It is predicted to fold into a small open barrel structure decorated with helices. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF26948"
] | [
"DUF8296"
] | [
46
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Caudoviricetes",
"marine sediment metagenome"
] | [
30,
11,
5
] | 3 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8296 | Domain of unknown function DUF8296 | DUF8296 | 6 |
IPR059341 | 59,341 | Domain of unknown function DUF8297 | DUF8297 | Domain | 20 | false | false | This domain is found in uncharacterised proteins mainly from Mycoplasma. It is predicted to fold into a β-sandwich. It contains two pairs of conserved cysteine residues that are predicted to form disulfide bonds. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF26949"
] | [
"DUF8297"
] | [
20
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Mycoplasma haematolamae (strain Purdue)"
] | [
20
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8297 | Domain of unknown function DUF8297 | DUF8297 | 7 |
IPR059343 | 59,343 | Domain of unknown function DUF8299 | DUF8299 | Domain | 49 | false | false | This domain is found in uncharacterised bacterial proteins. It is predicted to fold into array of α-helices. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF26951"
] | [
"DUF8299"
] | [
49
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria"
] | [
49
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8299 | Domain of unknown function DUF8299 | DUF8299 | 3 |
IPR059344 | 59,344 | Domain of unknown function DUF8300 | DUF8300 | Domain | 15 | false | false | This domain is found in uncharacterised proteins from proteobacteria. It is predicted to fold into a mainly α-helical structure and is frequently found in combination with PKD or GEVED domains. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF26952"
] | [
"DUF8300"
] | [
15
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Pseudomonadati"
] | [
15
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8300 | Domain of unknown function DUF8300 | DUF8300 | 2 |
IPR059345 | 59,345 | Domain of unknown function DUF8301 | DUF8301 | Domain | 34 | false | false | This domain is found in uncharacterised proteins mainly from Bacillales lineage. It is frequently found in combination with LXG domain ( ). | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF26953"
] | [
"DUF8301"
] | [
34
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillales"
] | [
34
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8301 | Domain of unknown function DUF8301 | DUF8301 | 1 |
IPR059346 | 59,346 | Domain of unknown function DUF8302 | DUF8302 | Domain | 210 | false | false | This entry represents a domain of unknown function mostly found in SAR organisms which includes stramenopiles, alveolates and rhizarians. It contains a similar fold to large ribosomal subunit proteins mL53 (MRPL44) which contains a β-sheet connected to two α-helices. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF26962"
] | [
"DUF8302"
] | [
210
] | 1 | [] | [] | [] | 0 | [
"9g6k",
"9i05"
] | 2 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
210
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8302 | Domain of unknown function DUF8302 | DUF8302 | 8 |
IPR059347 | 59,347 | Domain of unknown function DUF8303 | DUF8303 | Domain | 19 | false | false | This domain is found in uncharacterised bacterial proteins. It contains a semi-conserved PVxVP sequence motif. In some proteins it is found in combination with eCIS core domain ( ). | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF26963"
] | [
"DUF8303"
] | [
19
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria"
] | [
19
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8303 | Domain of unknown function DUF8303 | DUF8303 | 7 |
IPR059348 | 59,348 | Domain of unknown function DUF8304 | DUF8304 | Domain | 58 | false | false | This domain is found in uncharacterised eukaryotic proteins. It is predicted to five stranded antiparallel β-sheet packed on one side with α helices. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF26966"
] | [
"DUF8304"
] | [
58
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota",
"Mucilaginibacter yixingensis"
] | [
57,
1
] | 2 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8304 | Domain of unknown function DUF8304 | DUF8304 | 7 |
IPR059349 | 59,349 | Domain of unknown function DUF8305 | DUF8305 | Domain | 16 | false | false | This domain is found in uncharacterised proteins mainly from Clostridia lineage. It is predicted to fold into a globular structure with a β-sandwich topology. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF26969"
] | [
"DUF8305"
] | [
16
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eubacteriales",
"ecological metagenomes"
] | [
13,
3
] | 2 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8305 | Domain of unknown function DUF8305 | DUF8305 | 7 |
IPR059350 | 59,350 | Domain of unknown function DUF8306 | DUF8306 | Domain | 9 | false | false | This domain is found in uncharacterised bacterial proteins. It is predicted to adopt mainly α-helical structure flanked with a β-hairpin. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF26972"
] | [
"DUF8306"
] | [
9
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteroidota"
] | [
9
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8306 | Domain of unknown function DUF8306 | DUF8306 | 7 |
IPR059351 | 59,351 | Domain of unknown function DUF8307 | DUF8307 | Domain | 27 | false | false | This domain is found in uncharacterised proteins mainly from Actinomycetes. It contains a semi-conserved WGYxGxG sequence motif. It is predicted to fold into an α/β structure composed of antiparallel β-sheet and α-helices packed on one side. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF26974"
] | [
"DUF8307"
] | [
27
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Actinomycetes",
"Terrestrivirus sp.",
"Vitis vinifera"
] | [
22,
1,
4
] | 3 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8307 | Domain of unknown function DUF8307 | DUF8307 | 7 |
IPR059352 | 59,352 | Domain of unknown function DUF8308 | DUF8308 | Domain | 158 | false | false | This domain is found in uncharacterised phage proteins. It is predicted to fold into an α-helical structure. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF26975"
] | [
"DUF8308"
] | [
158
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Pseudomonadati",
"Ripduovirus RP12",
"viral metagenome"
] | [
155,
2,
1
] | 3 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8308 | Domain of unknown function DUF8308 | DUF8308 | 3 |
IPR059353 | 59,353 | Domain of unknown function DUF8309 | DUF8309 | Domain | 243 | false | false | This domain is found in uncharacterised bacterial proteins. It is predicted to fold into an α/β structure. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF26977"
] | [
"DUF8309"
] | [
243
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria"
] | [
243
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8309 | Domain of unknown function DUF8309 | DUF8309 | 3 |
IPR059354 | 59,354 | Domain of unknown function DUF8310 | DUF8310 | Domain | 24 | false | false | This domain is found in uncharacterised bacterial proteins. It is predicted to fold into a β-barrel structure. It contains several highly conserved positively charged residues that may be functionally important. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF26979"
] | [
"DUF8310"
] | [
24
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria"
] | [
24
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8310 | Domain of unknown function DUF8310 | DUF8310 | 3 |
IPR059355 | 59,355 | Domain of unknown function DUF8311 | DUF8311 | Domain | 25 | false | false | This domain is found in uncharacterised fungal proteins. It is predicted to adopt a globular structure composed of four stranded antiparallel β sheet and α helices packed on one side of it. It contains a number of positively charged residues which may be essential for function. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF26982"
] | [
"DUF8311"
] | [
25
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Agaricales"
] | [
25
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8311 | Domain of unknown function DUF8311 | DUF8311 | 5 |
IPR059356 | 59,356 | Domain of unknown function DUF8312 | DUF8312 | Domain | 7 | false | false | This domain is found in uncharacterised phage proteins. It is predicted to fold into an α-helical structure. It has several highly conserved cysteine residues some of which may coordinate a metal ion. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF26983"
] | [
"DUF8312"
] | [
7
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Alphaproteobacteria"
] | [
7
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8312 | Domain of unknown function DUF8312 | DUF8312 | 5 |
IPR059357 | 59,357 | Domain of unknown function DUF8313 | DUF8313 | Domain | 9 | false | false | This domain is found in uncharacterised fungal proteins. It contains several highly conserved cysteine residues that are predicted to form disulfide bonds. Some proteins contains two copies of this domain. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF26985"
] | [
"DUF8313"
] | [
9
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Ophiocordyceps australis"
] | [
9
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8313 | Domain of unknown function DUF8313 | DUF8313 | 5 |
IPR059358 | 59,358 | Domain of unknown function DUF8314 | DUF8314 | Domain | 206 | false | false | This entry represents a domain of unknown function in putative Ras GEF and other uncharacterised proteins mostly found in fungi. This domain belongs to proteins with a conserved four or five- helix up-and-down bundle structure. This structure is typical of focal adhesion targeting (FAT) domains and is responsible for d... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF26988"
] | [
"DUF8314"
] | [
206
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00004911",
"PUB00075415",
"PUB00161916"
] | [
"9159132",
"20399778",
"28860193"
] | [
"The I/LWEQ module: a conserved sequence that signifies F-actin binding in functionally diverse proteins from yeast to mammals.",
"The domain structure of talin: residues 1815-1973 form a five-helix bundle containing a cryptic vinculin-binding site.",
"Structural and functional insights into the interaction bet... | [
1997,
2010,
2017
] | 3 | [] | [] | 0 | 0 | null | [
"Fungi"
] | [
206
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8314 | Domain of unknown function DUF8314 | DUF8314 | 7 |
IPR059359 | 59,359 | Domain of unknown function DUF8315 | DUF8315 | Domain | 25 | false | false | This domain is found in uncharacterised proteins mainly from Campylobacterales. It is predicted to adopt an α/β structure composed of a four stranded antiparallel β-sheet and array of α-helices packed on it. It contains several conserved negatively charged residues that may be essential for function. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF26989"
] | [
"DUF8315"
] | [
25
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Arcobacteraceae"
] | [
25
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8315 | Domain of unknown function DUF8315 | DUF8315 | 1 |
IPR059360 | 59,360 | Domain of unknown function DUF8316 | DUF8316 | Domain | 634 | false | false | This entry represents a domain of unknown function at the N-terminal in putative histidine kinases mostly found in bacteria. This domain belongs to proteins with a conserved four or five- helix up-and-down bundle structure. This structure is typical of focal adhesion targeting (FAT) domains and is responsible for dimer... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF26990"
] | [
"DUF8316"
] | [
634
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00004911",
"PUB00075415",
"PUB00161916"
] | [
"9159132",
"20399778",
"28860193"
] | [
"The I/LWEQ module: a conserved sequence that signifies F-actin binding in functionally diverse proteins from yeast to mammals.",
"The domain structure of talin: residues 1815-1973 form a five-helix bundle containing a cryptic vinculin-binding site.",
"Structural and functional insights into the interaction bet... | [
1997,
2010,
2017
] | 3 | [] | [] | 0 | 0 | null | [
"Actinomycetes"
] | [
634
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8316 | Domain of unknown function DUF8316 | DUF8316 | 2 |
IPR059361 | 59,361 | Domain of unknown function DUF8317 | DUF8317 | Domain | 122 | false | false | This domain is found in uncharacterised proteins. It is predicted to fold into a six-stranded β-barrel with unique topology. It contains a conserved HDRxE sequence motif towards the C terminus. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF26991"
] | [
"DUF8317"
] | [
122
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Viruses",
"marine sediment metagenome"
] | [
93,
28,
1
] | 3 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8317 | Domain of unknown function DUF8317 | DUF8317 | 7 |
IPR059362 | 59,362 | Domain of unknown function DUF8318 | DUF8318 | Domain | 2,748 | false | false | This entry represents the domain of unknown function at the N-terminal domain in putative histidine kinases mostly found in bacteria. This domain (VBS) belongs to proteins with a conserved four or five- helix up-and-down bundle structure. This structure is typical of focal adhesion targeting (FAT) domains and is respon... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF26992"
] | [
"DUF8318"
] | [
2748
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00004911",
"PUB00075415",
"PUB00161916"
] | [
"9159132",
"20399778",
"28860193"
] | [
"The I/LWEQ module: a conserved sequence that signifies F-actin binding in functionally diverse proteins from yeast to mammals.",
"The domain structure of talin: residues 1815-1973 form a five-helix bundle containing a cryptic vinculin-binding site.",
"Structural and functional insights into the interaction bet... | [
1997,
2010,
2017
] | 3 | [] | [] | 0 | 0 | null | [
"Actinomycetota",
"metagenomes"
] | [
2741,
7
] | 2 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8318 | Domain of unknown function DUF8318 | DUF8318 | 3 |
IPR059363 | 59,363 | Domain of unknown function DUF8319 | DUF8319 | Domain | 22 | false | false | This domain is found in uncharacterised proteins mainly from Actinomycetes. It is predicted to fold into an unique α/β structure. In some proteins it is found inserted into a transmembrane domain. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF26993"
] | [
"DUF8319"
] | [
22
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Actinomycetes"
] | [
22
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8319 | Domain of unknown function DUF8319 | DUF8319 | 3 |
IPR059364 | 59,364 | Domain of unknown function DUF8320 | DUF8320 | Domain | 826 | false | false | This entry represents a domain of unknown function at the N-terminal in uncharacterised proteins mostly found in bacteria. This domain belongs to proteins with a conserved four or five-helix up-and-down bundle structure. This structure is typical of focal adhesion targeting (FAT) domains and is responsible for dimerisa... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF26994"
] | [
"DUF8320"
] | [
826
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00004911",
"PUB00075415",
"PUB00161916"
] | [
"9159132",
"20399778",
"28860193"
] | [
"The I/LWEQ module: a conserved sequence that signifies F-actin binding in functionally diverse proteins from yeast to mammals.",
"The domain structure of talin: residues 1815-1973 form a five-helix bundle containing a cryptic vinculin-binding site.",
"Structural and functional insights into the interaction bet... | [
1997,
2010,
2017
] | 3 | [] | [] | 0 | 0 | null | [
"Bacteria",
"freshwater metagenome"
] | [
816,
10
] | 2 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8320 | Domain of unknown function DUF8320 | DUF8320 | 9 |
IPR059365 | 59,365 | Domain of unknown function DUF8321 | DUF8321 | Domain | 5 | false | false | This domain is found in uncharacterised proteins. It is predicted to fold into an α-helical structure capped with a β-hairpin. It contains a conserved CFVxxR motif at the N-termini. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF26995"
] | [
"DUF8321"
] | [
5
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Glutinoglossum americanum",
"Pseudomonadati"
] | [
1,
4
] | 2 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8321 | Domain of unknown function DUF8321 | DUF8321 | 7 |
IPR059366 | 59,366 | Domain of unknown function DUF8322 | DUF8322 | Domain | 5 | false | false | This domain is found in uncharacterised proteins. It is predicted to fold into a β-barrel with topology reminiscent to PH domains but with circular permutation. It contains two conserved sequence motifs YDPN and YFxGG. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF26997"
] | [
"DUF8322"
] | [
5
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Glutinoglossum americanum",
"Pseudomonadati"
] | [
1,
4
] | 2 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8322 | Domain of unknown function DUF8322 | DUF8322 | 4 |
IPR059367 | 59,367 | Domain of unknown function DUF8323 | DUF8323 | Domain | 32 | false | false | This entry represents a domain of unknown function in a small group of proteins mostly found in animals , particularly nematodes. This domain contains a Spectrin fold with a conserved three-helix bundle structure that is typically arranged in tandem repeats. These repeats confer mechanical flexibility and structural re... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF26998"
] | [
"DUF8323"
] | [
32
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00161917"
] | [
"27698030"
] | [
"Cytoskeletal Integrators: The Spectrin Superfamily."
] | [
2016
] | 1 | [] | [] | 0 | 0 | null | [
"Spirurina"
] | [
32
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8323 | Domain of unknown function DUF8323 | DUF8323 | 9 |
IPR059368 | 59,368 | Domain of unknown function DUF8324 | DUF8324 | Domain | 122 | false | false | This entry represents a domain of unknown function in uncharacterised proteins mostly from plants. This domain contains a Spectring fold with a conserved three-helix bundle structure that is typically arranged in tandem repeats. These repeats confer mechanical flexibility and structural resilience, allowing the protein... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF27003"
] | [
"DUF8324"
] | [
122
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Poaceae"
] | [
122
] | 1 | [
"Oryza sativa subsp. japonica"
] | [
15
] | 1 | true | Domain | Domain of unknown function DUF8324 | Domain of unknown function DUF8324 | DUF8324 | 8 |
IPR059369 | 59,369 | Domain of unknown function DUF8325 | DUF8325 | Domain | 20 | false | false | This domain is found in uncharacterised proteins mainly from Alveolata lineage. It is predicted to adopt an α-helical structure. It contains several conserved positively charged residues predicted to be at the surface. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF27004"
] | [
"DUF8325"
] | [
20
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Alveolata"
] | [
20
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8325 | Domain of unknown function DUF8325 | DUF8325 | 9 |
IPR059370 | 59,370 | Domain of unknown function DUF8326 | DUF8326 | Domain | 142 | false | false | This entry represents a domain of unknown function in putative Ig-domain-containing proteins mainly from animals. This domain contains a Spectrin fold with a conserved three-helix bundle structure that is typically arranged in tandem repeats. These repeats confer mechanical flexibility and structural resilience, allowi... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF27005"
] | [
"DUF8326"
] | [
142
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00161917"
] | [
"27698030"
] | [
"Cytoskeletal Integrators: The Spectrin Superfamily."
] | [
2016
] | 1 | [] | [] | 0 | 0 | null | [
"Chromadorea"
] | [
142
] | 1 | [
"Caenorhabditis elegans"
] | [
1
] | 1 | true | Domain | Domain of unknown function DUF8326 | Domain of unknown function DUF8326 | DUF8326 | 1 |
IPR059371 | 59,371 | Domain of unknown function DUF8327 | DUF8327 | Domain | 34 | false | false | This domain is found in uncharacterised bacterial proteins. It is predicted to fold into an unique α/β structure composed of a curved β-sheet that wraps around a central α-helix. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF27006"
] | [
"DUF8327"
] | [
34
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteroidota",
"termite gut metagenome"
] | [
33,
1
] | 2 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8327 | Domain of unknown function DUF8327 | DUF8327 | 3 |
IPR059372 | 59,372 | Domain of unknown function DUF8328 | DUF8328 | Domain | 51 | false | false | This domain is found in uncharacterised bacterial proteins. It contains several highly conserved cysteine and histidine residues that may be involved in metal coordination. This domain is predicted to fold into a structure that resembles a double zinc ribbon domain with swapped knuckles. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF27007"
] | [
"DUF8328"
] | [
51
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"marine sediment metagenome"
] | [
49,
2
] | 2 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8328 | Domain of unknown function DUF8328 | DUF8328 | 9 |
IPR059373 | 59,373 | Domain of unknown function DUF8329 | DUF8329 | Domain | 23 | false | false | This domain is found in uncharacterised bacterial proteins. This domain is predicted to fold into an α/β structure composed of an antiparallel β-sheet with array of α-helices packed on it. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF27009"
] | [
"DUF8329"
] | [
23
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Clostridia"
] | [
23
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8329 | Domain of unknown function DUF8329 | DUF8329 | 1 |
IPR059374 | 59,374 | Domain of unknown function DUF8330 | DUF8330 | Domain | 13 | false | false | This domain is found in uncharacterised bacterial proteins. It is predicted to fold into an α/β structure composed of a curved β-sheet with α helices on one side. Some proteins contain two copies of this domain. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF27010"
] | [
"DUF8330"
] | [
13
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Clostridia",
"bioreactor metagenome"
] | [
11,
2
] | 2 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8330 | Domain of unknown function DUF8330 | DUF8330 | 7 |
IPR059375 | 59,375 | Protein of unknown function DUF8331 | DUF8331 | Family | 74 | false | false | This entry represents a conserved region found in uncharacterised proteins. It contains several highly conserved cysteine residues that are predicted to form disulfide bonds. These disulfide bonds are shared between β-hairpins and α-helical turns which are repeated along this region. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF27011"
] | [
"DUF8331"
] | [
74
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota",
"Polyangia"
] | [
13,
61
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function DUF8331 | Protein of unknown function DUF8331 | DUF8331 | 1 |
IPR059376 | 59,376 | Domain of unknown function DUF8332 | DUF8332 | Domain | 29 | false | false | This domain is found in uncharacterised proteins from betaproteobacteria. It contains a pair of highly conserved cysteine residues which are predicted to form a disulfide bond. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF27012"
] | [
"DUF8332"
] | [
29
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Betaproteobacteria",
"Gibberella intermedia"
] | [
28,
1
] | 2 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8332 | Domain of unknown function DUF8332 | DUF8332 | 3 |
IPR059377 | 59,377 | Domain of unknown function DUF8333 | DUF8333 | Domain | 57 | false | false | This domain is found in uncharacterised proteins mainly from Alveolata lineage. It contains several highly conserved cysteine residues which are predicted to form disulfide bonds. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF27013"
] | [
"DUF8333"
] | [
57
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Alveolata"
] | [
57
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8333 | Domain of unknown function DUF8333 | DUF8333 | 2 |
IPR059378 | 59,378 | Domain of unknown function DUF8334 | DUF8334 | Domain | 65 | false | false | This entry represents a domain of unknown function in uncharacterised proteins mostly found in Sar organisms. These proteins contain a SNARE-like fold. They are characterised by their tetrameric coiled-coil structures that facilitate membrane fusion processes. SNARE proteins are present in synaptic terminals, endoplasm... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF27014"
] | [
"DUF8334"
] | [
65
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00161918"
] | [
"32924745"
] | [
"New insights regarding SNARE proteins in autophagosome-lysosome fusion."
] | [
2021
] | 1 | [] | [] | 0 | 0 | null | [
"Plasmodium"
] | [
65
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8334 | Domain of unknown function DUF8334 | DUF8334 | 5 |
IPR059379 | 59,379 | Domain of unknown function DUF8335 | DUF8335 | Domain | 166 | false | false | This entry represents a domain of unknown function in putative TLC domain-containing and other uncharacterised proteins mostly found in fungi. These proteins contain a SNARE-like fold. They are characterised by their tetrameric coiled-coil structures that facilitate membrane fusion processes. SNARE proteins are present... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF27019"
] | [
"DUF8335"
] | [
166
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00161918"
] | [
"32924745"
] | [
"New insights regarding SNARE proteins in autophagosome-lysosome fusion."
] | [
2021
] | 1 | [] | [] | 0 | 0 | null | [
"leotiomyceta"
] | [
166
] | 1 | [
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)"
] | [
1
] | 1 | true | Domain | Domain of unknown function DUF8335 | Domain of unknown function DUF8335 | DUF8335 | 1 |
IPR059380 | 59,380 | Domain of unknown function DUF8336 | DUF8336 | Domain | 106 | false | false | This domain is found in uncharacterised bacterial proteins. It contains invariant histidine and three cysteine residues that are likely to coordinate a metal ion. It belongs to the superfamily of HC3 zinc fingers. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF27025"
] | [
"DUF8336"
] | [
106
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Halobacteriales",
"Streptomyces phage TurkishDelight"
] | [
103,
2,
1
] | 3 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8336 | Domain of unknown function DUF8336 | DUF8336 | 3 |
IPR059381 | 59,381 | Domain of unknown function DUF8337 | DUF8337 | Domain | 54 | false | false | This domain is found in uncharacterised bacterial proteins. It is predicted to adopt unusual α/β structure. It contains a conserved H[FY]F sequence motif. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF27026"
] | [
"DUF8337"
] | [
54
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria"
] | [
54
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8337 | Domain of unknown function DUF8337 | DUF8337 | 1 |
IPR059382 | 59,382 | Domain of unknown function DUF8338 | DUF8338 | Domain | 8 | false | false | This domain is found in a group of uncharacterised proteins mainly from Alveolata lineage. It contains several highly conserved cysteine residues that are predicted to form disulfide bonds. In many proteins this domain is followed by a helix which is predicted as a transmembrane. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF27029"
] | [
"DUF8338"
] | [
8
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Dinophyceae"
] | [
8
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8338 | Domain of unknown function DUF8338 | DUF8338 | 7 |
IPR059383 | 59,383 | Domain of unknown function DUF8339 | DUF8339 | Domain | 648 | false | false | This domain is found in uncharacterised proteins from proteobacteria. It contain several conserved cysteine residues that are predicted to form disulfide bonds. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF27031"
] | [
"DUF8339"
] | [
648
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Pseudomonadota"
] | [
648
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8339 | Domain of unknown function DUF8339 | DUF8339 | 5 |
IPR059384 | 59,384 | Domain of unknown function DUF8340 | DUF8340 | Domain | 980 | false | false | This entry represents a domain of unknown function in uncharacterised fungal proteins. This domain contains a nucleotide-binding like fold, typical of ATPases. This domain forms an alpha/beta canonical fold. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF27033"
] | [
"DUF8340"
] | [
980
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Actinomycetes",
"Eukaryota"
] | [
12,
968
] | 2 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8340 | Domain of unknown function DUF8340 | DUF8340 | 1 |
IPR059385 | 59,385 | Domain of unknown function DUF8341 | DUF8341 | Domain | 364 | false | false | This entry represents a domain of unknown function at the C-terminal in uncharacterised proteins mainly from Pseudomonadati. This domain contains a RNase like fold. The core architecture typically features a central five-stranded β-sheet flanked by several α-helices. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF27037"
] | [
"DUF8341"
] | [
364
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Epsilonproteobacteria",
"hydrothermal vent metagenome"
] | [
359,
5
] | 2 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8341 | Domain of unknown function DUF8341 | DUF8341 | 2 |
IPR059386 | 59,386 | Domain of unknown function DUF8342 | DUF8342 | Domain | 46 | false | false | This entry represents a domain of unknown function at the N-terminal in uncharacterised eukaryotic proteins mainly from Trypanosoma. This domain contains a RNase-like fold. The core architecture typically features a central five-stranded β-sheet flanked by several α-helices. This domain can be found associated with . | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF27040"
] | [
"DUF8342"
] | [
46
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Metakinetoplastina"
] | [
46
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8342 | Domain of unknown function DUF8342 | DUF8342 | 5 |
IPR059388 | 59,388 | Domain of unknown function DUF8344 | DUF8344 | Domain | 72 | false | false | This domain is found in uncharacterised proteins mainly from Myxococcota lineage. It is predicted to fold into a globular structure comprising a four stranded β-sheet packed with two helices. It contains two highly conserved cysteine and a histidine residues that may coordinate a metal ion. The position of the fourth r... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF27043"
] | [
"DUF8344"
] | [
72
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Myxococcota"
] | [
72
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8344 | Domain of unknown function DUF8344 | DUF8344 | 1 |
IPR059389 | 59,389 | Domain of unknown function DUF8345 | DUF8345 | Domain | 75 | false | false | This entry represents a domain found in PXO2-28 from Bacillus anthracis and related Bacilli. It has a β-sandwich fold. The domain occurs in proteins that are likely to be presented on the bacterial cell surface. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF27071"
] | [
"DUF8345"
] | [
75
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillota"
] | [
75
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8345 | Domain of unknown function DUF8345 | DUF8345 | 4 |
IPR059391 | 59,391 | Domain of unknown function DUF8347 | DUF8347 | Domain | 70 | false | false | This domain is found in uncharacterised proteins mainly from Gram negative bacteria. It is predicted to fold into an α-β-β architecture featuring two sandwiched β-sheets and α-helices packed on one side. This domain contains several negatively charged residues which are located on the domain surface and highly conserve... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF27110"
] | [
"DUF8347"
] | [
70
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Pseudomonadati",
"bioreactor metagenome",
"candidate division MSBL1"
] | [
67,
1,
2
] | 3 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8347 | Domain of unknown function DUF8347 | DUF8347 | 9 |
IPR059392 | 59,392 | Domain of unknown function DUF8348 | DUF8348 | Domain | 1,801 | false | false | This entry represents an uncharacterised domain found in fungal multidomain proteins. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF27504"
] | [
"DUF8348"
] | [
1801
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
1801
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8348 | Domain of unknown function DUF8348 | DUF8348 | 3 |
IPR059393 | 59,393 | Domain of unknown function DUF8349 | DUF8349 | Domain | 399 | false | false | This domain of unknown function is found in human Ras-related protein Rab-34, isoform NARR and related proteins. It contains several RP motifs. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF27509"
] | [
"DUF8349"
] | [
399
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"invertebrate metagenome"
] | [
14,
384,
1
] | 3 | [
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
4,
1,
2
] | 3 | true | Domain | Domain of unknown function DUF8349 | Domain of unknown function DUF8349 | DUF8349 | 8 |
IPR059394 | 59,394 | Domain of unknown function DUF8350 | DUF8350 | Domain | 364 | false | false | This domain is found in uncharacterised proteins mainly from Actinomycetes. It is predicted to fold into an array of α-helices. Some members have a small three-helical bundle inserted into it. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF27615"
] | [
"DUF8350"
] | [
364
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Actinomycetes"
] | [
364
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8350 | Domain of unknown function DUF8350 | DUF8350 | 4 |
IPR059395 | 59,395 | Domain of unknown function DUF8351 | DUF8351 | Domain | 4 | false | false | This domain is found in uncharacterised proteins from Gram-negative bacteria. It is predicted to fold into α/β structure comprising a curved β-sheet and an α helix packed on it. It has a number of conserved negatively charged residues that are predicted to cluster on the protein domain surface. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF27616"
] | [
"DUF8351"
] | [
4
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Pseudomonadati"
] | [
4
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8351 | Domain of unknown function DUF8351 | DUF8351 | 5 |
IPR059397 | 59,397 | Domain of unknown function DUF8353 | DUF8353 | Domain | 87 | false | false | This domain is found in uncharacterised proteins mainly from Ascomycota. It is predicted to adopt a globular structure composed of array of α-helices. It contains a semi-conserved CxxYPNH sequence motif which may have a functional importance. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF27619"
] | [
"DUF8353"
] | [
87
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"leotiomyceta"
] | [
87
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8353 | Domain of unknown function DUF8353 | DUF8353 | 2 |
IPR059398 | 59,398 | Domain of unknown function DUF8354 | DUF8354 | Domain | 59 | false | false | This domain is found in uncharacterised proteins mainly from gammaproteobacteria. It is predicted to fold into a helical structure. It contains two highly conserved sequence motifs HxAWRYL and RAHNW that may be of functional importance. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF27620"
] | [
"DUF8354"
] | [
59
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Gammaproteobacteria"
] | [
59
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8354 | Domain of unknown function DUF8354 | DUF8354 | 8 |
IPR059399 | 59,399 | Domain of unknown function DUF8355 | DUF8355 | Domain | 259 | false | false | This domain is found in uncharacterised proteins from proteobacteria. It is predicted to fold into a partly open β-barrel elaborated with α-helices. It is frequently found with , a domain typical for Type IV pilus biogenesis factor PilY1 homologues. It contains two highly conserved cysteine residues which are predicted... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF27621"
] | [
"DUF8355"
] | [
259
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"hydrothermal vent metagenome"
] | [
258,
1
] | 2 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8355 | Domain of unknown function DUF8355 | DUF8355 | 3 |
IPR059400 | 59,400 | Domain of unknown function DUF8356 | DUF8356 | Domain | 333 | false | false | This domain is found in uncharacterised proteins from Ascomycota lineage. It is predicted to fold into array of α-helices capped with a small three-stranded β-sheet. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF27622"
] | [
"DUF8356"
] | [
333
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Pezizomycotina"
] | [
333
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8356 | Domain of unknown function DUF8356 | DUF8356 | 2 |
IPR059401 | 59,401 | Domain of unknown function DUF8357 | DUF8357 | Domain | 136 | false | false | This domain is found in uncharacterised metazoan proteins. It is predicted to fold into a β-sandwich. It contains conserved cysteine residues which are predicted to form disulfide bonds. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF27623"
] | [
"DUF8357"
] | [
136
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Spiralia"
] | [
136
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8357 | Domain of unknown function DUF8357 | DUF8357 | 7 |
IPR059402 | 59,402 | Domain of unknown function DUF8358 | DUF8358 | Domain | 14 | false | false | This domain is found in uncharacterised proteins mainly from Agaricales lineage. It is predicted to fold into an α/β structure composed of a small three-stranded β-sheet and array of α-helices. This domain contains a highly conserved FGCWY sequence motif that may be important for function. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF27625"
] | [
"DUF8358"
] | [
14
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Agaricales"
] | [
14
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8358 | Domain of unknown function DUF8358 | DUF8358 | 6 |
IPR059403 | 59,403 | Domain of unknown function DUF8359 | DUF8359 | Domain | 141 | false | false | This domain is found in uncharacterised bacterial proteins.It is predicted to adopt a complex unique structure. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF27633"
] | [
"DUF8359"
] | [
141
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Dulem virus 40",
"metagenomes"
] | [
137,
1,
3
] | 3 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8359 | Domain of unknown function DUF8359 | DUF8359 | 1 |
IPR059405 | 59,405 | Domain of unknown function DUF8361 | DUF8361 | Domain | 314 | false | false | This domain is found in uncharacterised proteins from bacteria and eukaryotes. It is predicted to fold into a globular structure composed of a mixed β-sheet and α-helices packed on both sides of it. It contains several conserved cysteine residues which are predicted to form disulfide bonds. In addition, there highly co... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF27674"
] | [
"DUF8361"
] | [
314
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Viruses",
"metagenomes"
] | [
38,
234,
14,
28
] | 4 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8361 | Domain of unknown function DUF8361 | DUF8361 | 5 |
IPR059406 | 59,406 | Domain of unknown function DUF8362 | DUF8362 | Domain | 25 | false | false | This domain is found in uncharacterised archaeal proteins. It is predicted to fold into a β-sandwich structure decorated with α-helices. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF27819"
] | [
"DUF8362"
] | [
25
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"candidate division Kazan bacterium"
] | [
24,
1
] | 2 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8362 | Domain of unknown function DUF8362 | DUF8362 | 3 |
IPR059407 | 59,407 | Domain of unknown function DUF8363 | DUF8363 | Domain | 1,064 | false | false | This domain is found in uncharacterised eukaryotic proteins and predominantly in fungi. It contains highly conserved cysteine and histidine residues which are likely to coordinate a metal ion. These residues are predicted to come close in space and assemble in a shape typical for CCHC zinc finger domains. This domain i... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF27939"
] | [
"DUF8363"
] | [
1064
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota",
"Mouse intracisternal a-particle MIA14"
] | [
1063,
1
] | 2 | [
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)"
] | [
1,
3
] | 2 | true | Domain | Domain of unknown function DUF8363 | Domain of unknown function DUF8363 | DUF8363 | 8 |
IPR059408 | 59,408 | Domain of unknown function DUF8364 | DUF8364 | Domain | 18 | false | false | This domain is found in uncharacterised proteins mainly from Actinomycetes. It is predicted to adopt a globular structure in which two α-helices are sandwiched between two four-stranded β-sheets. Besides a conserved RxF sequence motif, this domain contains several conserved positively charged residues which may be esse... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF27965"
] | [
"DUF8364"
] | [
18
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Actinomycetes"
] | [
18
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8364 | Domain of unknown function DUF8364 | DUF8364 | 1 |
IPR059409 | 59,409 | Domain of unknown function DUF8365 | DUF8365 | Domain | 54 | false | false | This domain is found in uncharacterised fungal proteins. It is predicted to fold into a two layer α/β structure composed of an antiparallel β-sheet and three α-helices packed on one side. It contains several highly conserved cysteine residues predicted to form disulfide bonds. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF28038"
] | [
"DUF8365"
] | [
54
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"leotiomyceta"
] | [
54
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8365 | Domain of unknown function DUF8365 | DUF8365 | 7 |
IPR059410 | 59,410 | Domain of unknown function DUF8366 | DUF8366 | Domain | 26 | false | false | This domain is found in uncharacterised proteins mainly from Ochrophyta lineage. It is predicted to fold into a structure with a shape of a double barrel. It contains a highly conserved APQFxSxGVGYxRLGDD sequence motif that probably defines an interaction interface. In some proteins, it is found in combination with SAM... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF28039"
] | [
"DUF8366"
] | [
26
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Ochrophyta"
] | [
26
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8366 | Domain of unknown function DUF8366 | DUF8366 | 6 |
IPR059411 | 59,411 | Domain of unknown function DUF8367 | DUF8367 | Domain | 50 | false | false | This domain is found in uncharacterised bacterial proteins. It is predicted to fold into a β-sandwich-like structure with a conserved acidic patch on the surface. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF28040"
] | [
"DUF8367"
] | [
50
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"bioreactor metagenome"
] | [
49,
1
] | 2 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8367 | Domain of unknown function DUF8367 | DUF8367 | 4 |
IPR059412 | 59,412 | Domain of unknown function DUF8368 | DUF8368 | Domain | 33 | false | false | This domain is found in uncharacterised plant proteins. It is predicted to fold into mainly helical structure and is frequently found in combination with ATPase domains. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF28041"
] | [
"DUF8368"
] | [
33
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Viridiplantae"
] | [
33
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8368 | Domain of unknown function DUF8368 | DUF8368 | 9 |
IPR059413 | 59,413 | Domain of unknown function DUF8369 | DUF8369 | Domain | 1,059 | false | false | This domain is found in uncharacterised fungal proteins. It is predicted to fold into an α/β structure composed of a four-stranded antiparallel β-sheet packed on both sides with α-helices. It also contains a long α-hairpin, stabilised by conserved interactions, which is inserted after the first strand and may be functi... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF28122"
] | [
"DUF8369"
] | [
1059
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
1059
] | 1 | [
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)"
] | [
1
] | 1 | true | Domain | Domain of unknown function DUF8369 | Domain of unknown function DUF8369 | DUF8369 | 2 |
IPR059414 | 59,414 | Domain of unknown function DUF8370 | DUF8370 | Domain | 1,027 | false | false | This domain is found in uncharacterised bacterial proteins. It is predicted to adopt a globular structure composed of array of α-helices. It contains several highly conserved negatively charged residues that cluster in space and may be important for function. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF28123"
] | [
"DUF8370"
] | [
1027
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Siphoviridae sp. ctsoB6",
"Stenosarchaea group",
"metagenomes"
] | [
1006,
1,
3,
17
] | 4 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8370 | Domain of unknown function DUF8370 | DUF8370 | 8 |
IPR059415 | 59,415 | Domain of unknown function DUF8371 | DUF8371 | Domain | 890 | false | false | This domain is found in uncharacterised bacterial proteins. It is predicted to fold into an α/β structure composed of a central five-stranded mixed β-sheet and α-helices packed on both sides. This domain has a significant structural similarity to domains members of PD-(D/E)XK nuclease superfamily that extends to the ac... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF28130"
] | [
"DUF8371"
] | [
890
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Metazoa",
"Methanobacteriota",
"metagenomes"
] | [
850,
2,
19,
19
] | 4 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8371 | Domain of unknown function DUF8371 | DUF8371 | 9 |
IPR059416 | 59,416 | Domain of unknown function DUF8372 | DUF8372 | Domain | 1,341 | false | false | This domain is found in uncharacterised fungal proteins. It is predicted to fold into an α/β structure composed of an open β-barrel with α-helices packed on one side. It contains highly conserved G[FWY][DE] sequence motif that may be important for function. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF28131"
] | [
"DUF8372"
] | [
1341
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Pezizomycotina"
] | [
1341
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8372 | Domain of unknown function DUF8372 | DUF8372 | 1 |
IPR059418 | 59,418 | Repeat of unknown function DUF8374 | DUF8374 | Repeat | 1,262 | false | false | This is a region of tetratricopeptide (TPR)-like repeats found in a group of uncharacterised proteins from proteobacteria. Its function is unknown. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF28160"
] | [
"DUF8374"
] | [
1262
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Pseudomonadati"
] | [
1262
] | 1 | [] | [] | 0 | true | Repeat | Repeat of unknown function DUF8374 | Repeat of unknown function DUF8374 | DUF8374 | 3 |
IPR059419 | 59,419 | Domain of unknown function DUF8375 | DUF8375 | Domain | 157 | false | false | This entry represents a domain found in uncharacterised fungal proteins. The N- and C-terminal ends of this domain contain cysteine residues that are predicted to form a disulfide bond. The exact sequence position of these cysteines is not strictly conserved. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF28210"
] | [
"DUF8375"
] | [
157
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Pezizomycotina"
] | [
157
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8375 | Domain of unknown function DUF8375 | DUF8375 | 2 |
IPR059420 | 59,420 | Domain of unknown function DUF8376 | DUF8376 | Domain | 57 | false | false | This domain is found in uncharacterised fungal proteins. It contains several conserved cysteine residues which are predicted to form disulfide bonds. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF28252"
] | [
"DUF8376"
] | [
57
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Hypocreales"
] | [
57
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8376 | Domain of unknown function DUF8376 | DUF8376 | 8 |
IPR059421 | 59,421 | Domain of unknown function DUF8377 | DUF8377 | Domain | 104 | false | false | This domain is found in uncharacterised proteins from phages and prophages. It is predicted to fold into a globular structure with sandwich-like topology. It contains a conserved Gx(3)WSA sequence motif. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF28254"
] | [
"DUF8377"
] | [
104
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Caudoviricetes"
] | [
93,
11
] | 2 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8377 | Domain of unknown function DUF8377 | DUF8377 | 1 |
IPR059423 | 59,423 | Domain of unknown function DUF8379 | DUF8379 | Domain | 38 | false | false | This domain is found in uncharacterised proteins from Gammaproteobacteria. It is predicted to fold into a β-meander that curves around a single α-helix. It contains two conserved sequence motifs DxDGxxD and QxPP. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF28292"
] | [
"DUF8379"
] | [
38
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Gammaproteobacteria"
] | [
38
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8379 | Domain of unknown function DUF8379 | DUF8379 | 4 |
IPR059425 | 59,425 | Domain of unknown function DUF8381 | DUF8381 | Domain | 1,179 | false | false | This domain is found in uncharacterised proteins from Metazoa. It is predicted to fold into an α/β structure composed of mixed β-sheet and helices packed on one side of it. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF28323"
] | [
"DUF8381"
] | [
1179
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Tylenchoidea"
] | [
1179
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8381 | Domain of unknown function DUF8381 | DUF8381 | 6 |
IPR059426 | 59,426 | Domain of unknown function DUF8382 | DUF8382 | Domain | 22 | false | false | This domain is found in uncharacterised fungal proteins. It contains three cysteine and histidine residues which are highly conserved. They are predicted to come close in space and probably form a metal coordination site. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF28346"
] | [
"DUF8382"
] | [
22
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Dacrymycetaceae"
] | [
22
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8382 | Domain of unknown function DUF8382 | DUF8382 | 1 |
IPR059427 | 59,427 | Domain of unknown function DUF8383 | DUF8383 | Domain | 1,967 | false | false | This immunoglobulin-like (Ig-like) domain is found at the N-terminal end in a group of uncharacterised proteins from fungi. It shows a highly conserved motif GSWD and several highly conserved Y residues. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF28357"
] | [
"DUF8383"
] | [
1967
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Opisthokonta"
] | [
1967
] | 1 | [
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)"
] | [
3
] | 1 | true | Domain | Domain of unknown function DUF8383 | Domain of unknown function DUF8383 | DUF8383 | 4 |
IPR059429 | 59,429 | Domain of unknown function DUF8385 | DUF8385 | Domain | 63 | false | false | This domain is found in uncharacterised bacterial proteins. It is predicted to fold into an α/β structure composed of a central four stranded beβta-sheet packed on both sides with α helices. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF28363"
] | [
"DUF8385"
] | [
63
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Aduncisulcus paluster",
"Bacteria",
"marine sediment metagenome"
] | [
1,
61,
1
] | 3 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8385 | Domain of unknown function DUF8385 | DUF8385 | 2 |
IPR059430 | 59,430 | Domain of unknown function DUF8386 | DUF8386 | Domain | 57 | false | false | This domain is found in uncharacterised proteins mainly from Alveolata lineage It is predicted to adopt a complex structure composed of a four helical bundle that caps a small open β-barrel which is formed by the N- and the C- terminal parts of the domain. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF28378"
] | [
"DUF8386"
] | [
57
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Sar"
] | [
57
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8386 | Domain of unknown function DUF8386 | DUF8386 | 5 |
IPR059431 | 59,431 | Domain of unknown function DUF8387 | DUF8387 | Domain | 598 | false | false | This immunoglobulin-like (Ig-like) domain is found in a group of uncharacterised plant proteins. It is usually found associated with . | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF28382"
] | [
"DUF8387"
] | [
598
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Embryophyta"
] | [
598
] | 1 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
7,
3,
7
] | 3 | true | Domain | Domain of unknown function DUF8387 | Domain of unknown function DUF8387 | DUF8387 | 2 |
IPR059432 | 59,432 | Domain of unknown function DUF8388 | DUF8388 | Domain | 144 | false | false | This domain is found in uncharacterised eukaryotic proteins. It is predicted to fold into an α/β structure composed of a five stranded β-sheet and α-helices packed on one side of it. It is preceded by a transmembrane domain. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF28383"
] | [
"DUF8388"
] | [
144
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
144
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8388 | Domain of unknown function DUF8388 | DUF8388 | 9 |
IPR059433 | 59,433 | Domain of unknown function DUF8389 | DUF8389 | Domain | 43 | false | false | This domain is found in uncharacterised bacterial proteins. It is predicted to adopt a structure which resembles the conserved core of the N-terminal domain of PatA . | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF28390"
] | [
"DUF8389"
] | [
43
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria"
] | [
43
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8389 | Domain of unknown function DUF8389 | DUF8389 | 6 |
IPR059434 | 59,434 | Domain of unknown function DUF8390 | DUF8390 | Domain | 160 | false | false | This immunoglobulin-like (Ig-like) domain is found in a group of uncharacterised EFG-containing proteins from amoebas that are predicted to show several Ig-like domains. This entry is often found associated with , , and . | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF28405"
] | [
"DUF8390"
] | [
160
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Dictyostelia"
] | [
160
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8390 | Domain of unknown function DUF8390 | DUF8390 | 2 |
IPR059435 | 59,435 | Domain of unknown function DUF8391 | DUF8391 | Domain | 195 | false | false | This immunoglobulin-like (Ig-like) domain is found in a group of uncharacterised proteins from worms. It has several highly conserved W, Y and C residues. Its specific function is unknown. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF28429"
] | [
"DUF8391"
] | [
195
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Nematoda"
] | [
195
] | 1 | [
"Caenorhabditis elegans"
] | [
5
] | 1 | true | Domain | Domain of unknown function DUF8391 | Domain of unknown function DUF8391 | DUF8391 | 6 |
IPR059436 | 59,436 | Domain of unknown function DUF8392 | DUF8392 | Domain | 246 | false | false | This immunoglobulin-like (Ig-like) domain is found in a group of uncharacterised fungal proteins. It is often found associated with and has a highly conserved motif ISGFP. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF28431"
] | [
"DUF8392"
] | [
246
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Pezizomycotina"
] | [
246
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8392 | Domain of unknown function DUF8392 | DUF8392 | 2 |
IPR059437 | 59,437 | Domain of unknown function DUF8393 | DUF8393 | Domain | 2,259 | false | false | This immunoglobulin-like (Ig-like) domain is found in a group of uncharacterised proteobacterial proteins. It is often found associated with , and and has conserved P, L, F and D residues. Its function is unknown. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF28432"
] | [
"DUF8393"
] | [
2259
] | 1 | [] | [] | [] | 0 | [
"6c29"
] | 1 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Opisthokonta",
"metagenomes"
] | [
2250,
2,
7
] | 3 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8393 | Domain of unknown function DUF8393 | DUF8393 | 2 |
IPR059438 | 59,438 | Domain of unknown function DUF8394 | DUF8394 | Domain | 516 | false | false | This domain is found in uncharacterised proteins mainly from Actinomycetota lineage. It is predicted to adopt a complex α/β structure resembling the shape of 'stalk and head'. Structurally it is similar to the so-called choice-of-anchor G proteins, which are sortase and exosortase targets, and are likely to be found on... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF28433"
] | [
"DUF8394"
] | [
516
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillati",
"bioreactor metagenome"
] | [
515,
1
] | 2 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8394 | Domain of unknown function DUF8394 | DUF8394 | 2 |
IPR059439 | 59,439 | Domain of unknown function DUF8395 | DUF8395 | Domain | 1,466 | false | false | This domain is found in the uncharacterised protein At4g14100 from Arabidopsis thaliana and similar plant sequences. It is predicted to form unclosed β-barrel and an α-helical lid. Its function is unknown. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF28435"
] | [
"DUF8395"
] | [
1466
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
1466
] | 1 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
9,
12,
18
] | 3 | true | Domain | Domain of unknown function DUF8395 | Domain of unknown function DUF8395 | DUF8395 | 9 |
IPR059440 | 59,440 | Protein of unknown function DUF8396 | DUF8396 | Family | 49 | false | false | This entry represents a group of uncharacterised bacterial proteins. They are probably associated with the membrane and are predicted to fold into a large barrel structure which in addition to an internal plug contains an insertion which points out of the barrel. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF28436"
] | [
"DUF8396"
] | [
49
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria"
] | [
49
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF8396 | Protein of unknown function DUF8396 | DUF8396 | 1 |
IPR059441 | 59,441 | Domain of unknown function DUF8397 | DUF8397 | Domain | 417 | false | false | This domain is found in uncharacterised fungal proteins. It is predicted to fold into array of α-helices some of which connected by extended loops. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF28437"
] | [
"DUF8397"
] | [
417
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Agaricomycetes"
] | [
417
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF8397 | Domain of unknown function DUF8397 | DUF8397 | 3 |
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