interpro_id
string
interpro_numeric_id
int64
name
string
short_name
string
entry_type
string
protein_count
int64
is_llm
bool
is_llm_reviewed
bool
abstract
string
go_ids
list
go_terms
list
go_categories
list
go_count
int64
member_databases
list
member_accessions
list
member_names
list
member_protein_counts
list
member_count
int64
external_databases
list
external_accessions
list
external_xrefs
list
external_xref_count
int64
pdb_ids
list
structure_count
int64
publication_ids
list
pubmed_ids
list
publication_titles
list
publication_years
list
publication_count
int64
parent_ids
list
child_ids
list
parent_count
int64
child_count
int64
tree_depth
float64
taxonomy_names
list
taxonomy_protein_counts
list
taxonomy_count
int64
key_species_names
list
key_species_protein_counts
list
key_species_count
int64
in_entry_list
bool
entry_list_type
string
entry_list_name
string
names_dat_name
string
short_names_dat_name
string
split_bucket
int64
IPR059660
59,660
Cgl2226
Cgl2226
Domain
146
false
false
This entry represents Cgl2226 proteins found in Corynebacterium and related actinobacteria. The proteins are typically around 180 amino acids in length with a disordered C-terminal region rich in glycine residues. Cgl2226 has been detected in a cytochrome bc1-aa3 supercomplex in C. glutamicum, though its deletion does ...
[]
[]
[]
0
[ "PFAM" ]
[ "PF27333" ]
[ "Cgl2226" ]
[ 146 ]
1
[]
[]
[]
0
[]
0
[ "PUB00035558" ]
[ "12446663" ]
[ "Purification of a cytochrome bc-aa3 supercomplex with quinol oxidase activity from Corynebacterium glutamicum. Identification of a fourth subunity of cytochrome aa3 oxidase and mutational analysis of diheme cytochrome c1." ]
[ 2003 ]
1
[]
[]
0
0
null
[ "Corynebacterium" ]
[ 146 ]
1
[]
[]
0
true
Domain
Cgl2226
Cgl2226
Cgl2226
2
IPR059661
59,661
Y4bG, N-terminal domain
Y4bG_N
Domain
144
false
false
This entry represents the N-terminal domain of Y4bG proteins found in Sinorhizobium and related rhizobia. The full-length protein is 271 amino acids and contains a signal peptide at positions 1-22. Y4bG is encoded on the symbiotic plasmid pNGR234a in Sinorhizobium fredii, a bacterium involved in nitrogen-fixing symbios...
[]
[]
[]
0
[ "PFAM" ]
[ "PF27345" ]
[ "Y4bG_N" ]
[ 144 ]
1
[]
[]
[]
0
[]
0
[ "PUB00004254", "PUB00113962" ]
[ "9163424", "19376903" ]
[ "Molecular basis of symbiosis between Rhizobium and legumes.", "Rhizobium sp. strain NGR234 possesses a remarkable number of secretion systems." ]
[ 1997, 2009 ]
2
[]
[]
0
0
null
[ "Pseudomonadota" ]
[ 144 ]
1
[]
[]
0
true
Domain
Y4bG, N-terminal domain
Y4bG, N-terminal domain
Y4bG_N
9
IPR059662
59,662
Y07A
Y07A
Family
142
false
false
This entry represents the Y07A protein family found in T4-like bacteriophages. Y07A is an uncharacterised protein found in the e-segB intergenic region of bacteriophage T4. The protein is encoded within the phage genome that infects Escherichia coli. While the specific function of Y07A remains unknown, its genomic loca...
[]
[]
[]
0
[ "PFAM" ]
[ "PF26879" ]
[ "Phage_T4_Y07A" ]
[ 142 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Viruses" ]
[ 142 ]
1
[]
[]
0
true
Family
Y07A
Y07A
Y07A
8
IPR059663
59,663
Mycolysin, middle domain
Mycolysin_M
Domain
141
false
false
This entry represents the 7-stranded β-sandwich domain of mycolysin found in Streptomyces cacaoi. The full-length mycolysin precursor is 550 amino acids with a signal peptide (residues 1-34). Mycolysin is a zinc-dependent metalloprotease that preferentially cleaves bonds with hydrophobic residues [ , ]. The mature enzy...
[]
[]
[]
0
[ "PFAM" ]
[ "PF27283" ]
[ "Mycolysin_M" ]
[ 141 ]
1
[]
[]
[]
0
[]
0
[ "PUB00162182", "PUB00162183" ]
[ "2341042", "1740443" ]
[ "Extracellular metalloprotease gene of Streptomyces cacaoi: structure, nucleotide sequence and characterization of the cloned gene product.", "Extracellular autoprocessing of a metalloprotease from Streptomyces cacaoi." ]
[ 1990, 1992 ]
2
[]
[]
0
0
null
[ "Actinomycetes" ]
[ 141 ]
1
[]
[]
0
true
Domain
Mycolysin, middle domain
Mycolysin, middle domain
Mycolysin_M
5
IPR059664
59,664
HI_1570-like domain
HI_1570
Domain
142
false
false
This entry represents a small domain of approximately 40 residues found in uncharacterised proteins from Pasteurellales and Neisseriales. In the 169 amino acid protein HI_1570 from Haemophilus influenzae strain Rd, this domain is located at the N-terminal. However, in many other proteins this domain occupies a central ...
[]
[]
[]
0
[ "PFAM" ]
[ "PF27613" ]
[ "HI_1570" ]
[ 142 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Pseudomonadota", "unclassified Caudoviricetes" ]
[ 139, 3 ]
2
[]
[]
0
true
Domain
HI_1570-like domain
HI_1570-like domain
HI_1570
1
IPR059665
59,665
Lin0124, C-terminal domain
Lin0124_C
Domain
144
false
false
This entry represents the C-terminal domain of Lin0124 proteins. The domain forms a coiled-coil structure and is found in bacteria, particularly in Bacillota including Listeria. The function of this domain remains to be determined.
[]
[]
[]
0
[ "PFAM" ]
[ "PF27405" ]
[ "Lin0124_C" ]
[ 144 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria", "Brassica carinata", "Viruses" ]
[ 112, 1, 31 ]
3
[]
[]
0
true
Domain
Lin0124, C-terminal domain
Lin0124, C-terminal domain
Lin0124_C
7
IPR059666
59,666
SPbeta prophage YomF protein, N-terminal domain
YomF_N
Domain
139
false
false
This entry represents the N-terminal domain in YomF. The function of this domain remains unknown. YomF is an uncharacterised protein encoded by the SPbeta prophage in Bacillus subtilis. This protein contains an N-terminal domain , middle domain and a C-terminal domain .
[]
[]
[]
0
[ "PFAM" ]
[ "PF27067" ]
[ "YomF_N" ]
[ 139 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria", "Mesorhabditis spiculigera", "Viruses" ]
[ 133, 1, 5 ]
3
[]
[]
0
true
Domain
SPbeta prophage YomF protein, N-terminal domain
SPbeta prophage YomF protein, N-terminal domain
YomF_N
1
IPR059667
59,667
Exosporium protein A domain
CsxA
Domain
137
false
false
This entry represents the exosporium protein A (CsxA) family found in Clostridium species. CsxA localises to the exosporium, the outermost layer of the bacterial spore [ ]. The prototype member from Clostridium sporogenes is a 308 amino acid protein that forms part of the spore surface architecture. This protein is not...
[]
[]
[]
0
[ "PFAM" ]
[ "PF27077" ]
[ "CsxA" ]
[ 137 ]
1
[]
[]
[]
0
[]
0
[ "PUB00089400" ]
[ "27375261" ]
[ "Characterization of the spore surface and exosporium proteins of Clostridium sporogenes; implications for Clostridium botulinum group I strains." ]
[ 2016 ]
1
[]
[]
0
0
null
[ "Clostridia", "bioreactor metagenome" ]
[ 136, 1 ]
2
[]
[]
0
true
Domain
Exosporium protein A domain
Exosporium protein A domain
CsxA
1
IPR059668
59,668
AtcB, N-terminal domain
AtcB_N
Domain
133
false
false
This entry represents the N-terminal domain of adaptation to cold protein B (AtcB) found primarily in Shewanella and related marine bacteria. This domain adopts a helix-turn-helix fold. AtcB is a protein of approximately 252 amino acids that modulates RNA polymerase activity and is involved in cold adaptation [ , ]. Th...
[]
[]
[]
0
[ "PFAM" ]
[ "PF27486" ]
[ "AtcB_N" ]
[ 133 ]
1
[]
[]
[]
0
[]
0
[ "PUB00161810", "PUB00161811" ]
[ "31482142", "33341675" ]
[ "Cold adaptation in the environmental bacterium <i>Shewanella oneidensis</i> is controlled by a J-domain co-chaperone protein network.", "Modulation of the RNA polymerase activity by AtcB, a protein associated with a DnaK chaperone network in Shewanella oneidensis." ]
[ 2019, 2021 ]
2
[]
[]
0
0
null
[ "Bacteria" ]
[ 133 ]
1
[]
[]
0
true
Domain
AtcB, N-terminal domain
AtcB, N-terminal domain
AtcB_N
9
IPR059669
59,669
AtcB, C-terminal domain
AtcB_C
Domain
133
false
false
This entry represents the C-terminal domain of adaptation to cold protein B (AtcB) found primarily in Shewanella and related marine bacteria. AtcB is a protein of approximately 252 amino acids that modulates RNA polymerase activity and is involved in cold adaptation [ , ]. The protein interacts with RNA polymerase subu...
[]
[]
[]
0
[ "NCBIFAM", "PFAM" ]
[ "NF047889", "PF27450" ]
[ "ColdAdpAtcB", "AtcB_C" ]
[ 114, 133 ]
2
[]
[]
[]
0
[]
0
[ "PUB00161810", "PUB00161811" ]
[ "31482142", "33341675" ]
[ "Cold adaptation in the environmental bacterium <i>Shewanella oneidensis</i> is controlled by a J-domain co-chaperone protein network.", "Modulation of the RNA polymerase activity by AtcB, a protein associated with a DnaK chaperone network in Shewanella oneidensis." ]
[ 2019, 2021 ]
2
[]
[]
0
0
null
[ "Bacteria" ]
[ 133 ]
1
[]
[]
0
true
Domain
AtcB, C-terminal domain
AtcB, C-terminal domain
AtcB_C
2
IPR059673
59,673
TP_0070
TP_0070
Family
123
false
false
This entry represents the uncharacterised protein TP_0070 from Treponema pallidum and related spirochetes. The protein is 128 amino acids in length and contains four transmembrane helices forming a four-helix bundle. The protein is predicted to be localised to the cell membrane as a multi-pass membrane protein. The fun...
[]
[]
[]
0
[ "PFAM" ]
[ "PF27362" ]
[ "TP_0070" ]
[ 123 ]
1
[]
[]
[]
0
[]
0
[ "PUB00008137" ]
[ "9665876" ]
[ "Complete genome sequence of Treponema pallidum, the syphilis spirochete." ]
[ 1998 ]
1
[]
[]
0
0
null
[ "Bacteria", "Geodia barretti", "ecological metagenomes" ]
[ 120, 1, 2 ]
3
[]
[]
0
true
Family
TP_0070
TP_0070
TP_0070
5
IPR059674
59,674
MJ0538
MJ0538
Domain
124
false
false
This entry represents the MJ0538 uncharacterised proteins found in archaea. This domain is found in thermophilic and hyperthermophilic archaea including Thermococcaceae, Thermococcus, and Methanococcales, with some members in Candidatus Micrarchaeota. The proteins are approximately 260 amino acids in length. The functi...
[]
[]
[]
0
[ "PFAM" ]
[ "PF27325" ]
[ "MJ0538" ]
[ 124 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Archaea", "ecological metagenomes" ]
[ 116, 8 ]
2
[]
[]
0
true
Domain
MJ0538
MJ0538
MJ0538
4
IPR059675
59,675
Y16H
Y16H
Family
120
false
false
This entry represents the Y16H protein family found in T4-like bacteriophages. Y16H is an uncharacterised protein of 49 amino acids (4.8 kDa) found in the motA-Gp52 intergenic region of bacteriophage T4.
[]
[]
[]
0
[ "PFAM" ]
[ "PF26886" ]
[ "Phage_T4_Y16H" ]
[ 120 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Viruses" ]
[ 120 ]
1
[]
[]
0
true
Family
Y16H
Y16H
Y16H
6
IPR059676
59,676
Alr2735, C-terminal domain
Alr2735
Domain
116
false
false
This entry represents the C-terminal domain of Alr2735 proteins, whose function is unknown. This domain is found in cyanobacteria. These proteins are named after the alr2735 gene from Nostoc sp. PCC 7120.
[]
[]
[]
0
[ "PFAM" ]
[ "PF27288" ]
[ "Alr2735" ]
[ 116 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Cyanophyceae" ]
[ 116 ]
1
[]
[]
0
true
Domain
Alr2735, C-terminal domain
Alr2735, C-terminal domain
Alr2735
1
IPR059677
59,677
Mycolysin, N-terminal domain
Mycolysin_N
Domain
115
false
false
This entry represents the N-terminal domain of mycolysin proteins found in Streptomyces and related actinomycetes. The domain adopts an immunoglobulin-like fold structure. Mycolysin is a secreted zinc metalloprotease ( ) that preferentially cleaves bonds with hydrophobic residues [ , ]. The protein undergoes extracellu...
[]
[]
[]
0
[ "PFAM" ]
[ "PF27334" ]
[ "Mycolysin_N" ]
[ 115 ]
1
[]
[]
[]
0
[]
0
[ "PUB00162182", "PUB00162183" ]
[ "2341042", "1740443" ]
[ "Extracellular metalloprotease gene of Streptomyces cacaoi: structure, nucleotide sequence and characterization of the cloned gene product.", "Extracellular autoprocessing of a metalloprotease from Streptomyces cacaoi." ]
[ 1990, 1992 ]
2
[]
[]
0
0
null
[ "Actinomycetes", "Tetradesmus obliquus" ]
[ 113, 2 ]
2
[]
[]
0
true
Domain
Mycolysin, N-terminal domain
Mycolysin, N-terminal domain
Mycolysin_N
6
IPR059678
59,678
Y16N
Y16N
Family
114
false
false
This entry represents the Y16N protein family found in T4-like bacteriophages. Y16N is an uncharacterised protein of 42 amino acids (5.0 kDa) found in the ndd-denB intergenic region of bacteriophage T4.
[]
[]
[]
0
[ "PFAM" ]
[ "PF26889" ]
[ "Phage_T4_Y16N" ]
[ 114 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Viruses" ]
[ 114 ]
1
[]
[]
0
true
Family
Y16N
Y16N
Y16N
9
IPR059680
59,680
Tail fiber protein R
Tail_fiber_R
Family
114
false
false
This entry represents tail fiber protein R found in P1-like bacteriophages. This protein is a structural or assembly component of the tail fibres, which are essential for phage attachment to host cells. The protein is 144 amino acids in length and is encoded within the tail fibre operon of bacteriophage P1. Tail fibre ...
[]
[]
[]
0
[ "PFAM" ]
[ "PF26881" ]
[ "Phage_P1_tail_fiber_R" ]
[ 114 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Caudoviricetes", "Gammaproteobacteria", "feces metagenome" ]
[ 12, 101, 1 ]
3
[]
[]
0
true
Family
Tail fiber protein R
Tail fiber protein R
Tail_fiber_R
3
IPR059681
59,681
PopC secretion inhibitor
PopD
Domain
110
false
false
This entry represents the α-β plait fold domain found in PopD, a PopC secretion inhibitor from Myxococcus xanthus [ ]. PopD forms a cytoplasmic complex with PopC and inhibits PopC secretion and activity in non-starving cells. The protein is approximately 156 amino acids in length and contains a disordered N-terminal re...
[]
[]
[]
0
[ "PFAM" ]
[ "PF27478" ]
[ "PopD" ]
[ 110 ]
1
[]
[]
[]
0
[]
0
[ "PUB00082430" ]
[ "22404381" ]
[ "A RelA-dependent two-tiered regulated proteolysis cascade controls synthesis of a contact-dependent intercellular signal in Myxococcus xanthus." ]
[ 2012 ]
1
[]
[]
0
0
null
[ "Bacteria" ]
[ 110 ]
1
[]
[]
0
true
Domain
PopC secretion inhibitor
PopC secretion inhibitor
PopD
8
IPR059682
59,682
Alr2735, N-terminal domain
Alr2735_N
Domain
109
false
false
This entry represents the N-terminal domain of Alr2735 proteins found in cyanobacteria. Alr2735 proteins are found in Nostoc species. The full-length Alr2735 protein is approximately 210 amino acids. The specific function of this N-terminal domain remains to be determined. It contains an helical fold.
[]
[]
[]
0
[ "PFAM" ]
[ "PF27301" ]
[ "Alr2735_N" ]
[ 109 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Cyanophyceae" ]
[ 109 ]
1
[]
[]
0
true
Domain
Alr2735, N-terminal domain
Alr2735, N-terminal domain
Alr2735_N
7
IPR059684
59,684
PM0294, middle domain
PM0294_M
Domain
105
false
false
This entry represents the middle domain of PM0294, an uncharacterised protein from Pasteurella multocida. PM0294 is 423 amino acids in length. This domain is found predominantly in Bacteroidota, particularly within Flavobacteriia and Sphingobacteriia. The function of this middle domain remains to be determined.
[]
[]
[]
0
[ "PFAM" ]
[ "PF27496" ]
[ "PM0294_M" ]
[ 105 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Pseudomonadati" ]
[ 105 ]
1
[]
[]
0
true
Domain
PM0294, middle domain
PM0294, middle domain
PM0294_M
8
IPR059685
59,685
Y05J
Y05J
Family
105
false
false
This entry represents protein Y05J found in bacteriophages. The prototype is from bacteriophage T4, a small 34 amino acid protein with a molecular weight of 4.2 kDa located in the mobD-ri intergenic region. The protein is also known as mobD.2 or tk.-8 and is found in the nonessential region between the tk and nrdC gene...
[]
[]
[]
0
[ "PFAM" ]
[ "PF26864" ]
[ "Phage_T4_Y05J" ]
[ 105 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Caudoviricetes" ]
[ 105 ]
1
[]
[]
0
true
Family
Y05J
Y05J
Y05J
7
IPR059686
59,686
Uncharacterized protein gp6
Mup06
Family
103
false
false
This entry represents gene product 6 (gp6) found in bacteriophages. The prototype is from Escherichia phage Mu, a 76-amino-acid protein with a molecular weight of 8.5 kDa. Gp6 is an early protein expressed during the early phase of the viral replicative cycle. Expression is repressed by the viral Repc protein during la...
[]
[]
[]
0
[ "PFAM" ]
[ "PF26833" ]
[ "Phage_Mu_gp6" ]
[ 103 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Caudoviricetes", "Pseudomonadota" ]
[ 31, 72 ]
2
[]
[]
0
true
Family
Uncharacterized protein gp6
Uncharacterized protein gp6
Mup06
4
IPR059688
59,688
YomR, C-terminal domain
YomR_C
Domain
106
false
false
This entry represents the C-terminal domain of YomR proteins derived from SPbeta prophage and related bacteriophages. This domain adopts a β-sandwich fold similar to phage tail base-plate receptor-binding proteins found in Siphoviridae. The protein is found across 28 species including both bacteria and viruses, particu...
[]
[]
[]
0
[ "PFAM" ]
[ "PF27455" ]
[ "YomR_C" ]
[ 106 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria", "Caudoviricetes" ]
[ 103, 3 ]
2
[]
[]
0
true
Domain
YomR, C-terminal domain
YomR, C-terminal domain
YomR_C
4
IPR059689
59,689
AZC_3924
AZC_3924
Domain
98
false
false
This entry represents a small protein of approximately 84 amino acids found predominantly in bacteria. The protein is widely distributed across bacterial phyla including Pseudomonadota and Acidobacteriota, with representatives found in Alphaproteobacteria and Terriglobia. The function of this protein remains to be dete...
[]
[]
[]
0
[ "PFAM" ]
[ "PF27389" ]
[ "AZC_3924" ]
[ 98 ]
1
[]
[]
[]
0
[]
0
[ "PUB00161817" ]
[ "8471796" ]
[ "Azorhizobium caulinodans nitrogen fixation (nif/fix) gene regulation: mutagenesis of the nifA -24/-12 promoter element, characterization of a ntrA(rpoN) gene, and derivation of a model." ]
[ 1993 ]
1
[]
[]
0
0
null
[ "Pseudomonadati" ]
[ 98 ]
1
[]
[]
0
true
Domain
AZC_3924
AZC_3924
AZC_3924
4
IPR059690
59,690
MJ1308
MJ1308
Domain
93
false
false
This entry represents the MJ1308 family of small uncharacterised membrane proteins found in methanogenic archaea. The family is found across various methanogenic lineages including Methanobrevibacter, Methanobacterium, Methanosphaera, and Methanobacteriaceae. The proteins are approximately 108 amino acids in length and...
[]
[]
[]
0
[ "PFAM" ]
[ "PF27305" ]
[ "MJ1308" ]
[ 93 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Archaea", "Clostridium paridis", "bioreactor metagenome" ]
[ 91, 1, 1 ]
3
[]
[]
0
true
Domain
MJ1308
MJ1308
MJ1308
6
IPR059691
59,691
Y02C
Y02C
Family
91
false
false
This entry represents protein Y02C found in bacteriophages. The prototype is from bacteriophage T4, a 49 amino acid protein with a molecular weight of 5.6 kDa located in the Gp42-imm intergenic region. The protein is also known as 42.1 or T4T045 and remains uncharacterised. The function of this protein is unknown.
[]
[]
[]
0
[ "PFAM" ]
[ "PF26865" ]
[ "Phage_T4_Y02C" ]
[ 91 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Viruses" ]
[ 91 ]
1
[]
[]
0
true
Family
Y02C
Y02C
Y02C
9
IPR059692
59,692
Y4mA, C-terminal domain
Y4mA_C
Domain
92
false
false
This entry represents the C-terminal domain of y4mA proteins. The domain adopts an SH3-like fold structure and is found in bacteria, predominantly in Alphaproteobacteria with representatives in Hyphomicrobiales and Rhodobacterales orders. The function of this domain remains to be determined.
[]
[]
[]
0
[ "PFAM" ]
[ "PF27402" ]
[ "Y4mA_C" ]
[ 92 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Prasinoderma singulare", "Pseudomonadati", "ecological metagenomes", "uncultured Caudovirales phage" ]
[ 1, 83, 7, 1 ]
4
[]
[]
0
true
Domain
Y4mA, C-terminal domain
Y4mA, C-terminal domain
Y4mA_C
4
IPR059693
59,693
MJ1579
MJ1579
Family
90
false
false
This entry represents the MJ1579 family of small uncharacterised proteins found exclusively in archaea. The family is found predominantly in thermophilic and hyperthermophilic archaea including Thermococcus, Methanococcaceae, Methanocaldococcaceae, and Thermococcaceae, with some members in candidate division MSBL1. The...
[]
[]
[]
0
[ "PFAM" ]
[ "PF27357" ]
[ "MJ1579" ]
[ 90 ]
1
[]
[]
[]
0
[ "6e4j", "6ns8" ]
2
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Archaea", "uncultured organism" ]
[ 89, 1 ]
2
[]
[]
0
true
Family
MJ1579
MJ1579
MJ1579
2
IPR059694
59,694
Uncharacterized protein Gp2
Gp2
Domain
87
false
false
This entry represents gene product 2 (Gp2) found in N4-like bacteriophages. Gp2 is an uncharacterised protein of 161 amino acids (18.0 kDa) found in bacteriophage N4. Structure prediction strongly suggests that this protein forms homodimers which includes a strand swapped between the monomer structure.
[]
[]
[]
0
[ "PFAM" ]
[ "PF26984" ]
[ "Phage_N4_Gp2" ]
[ 87 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Lucilia cuprina", "Pseudomonadota", "Viruses" ]
[ 1, 2, 84 ]
3
[]
[]
0
true
Domain
Uncharacterized protein Gp2
Uncharacterized protein Gp2
Gp2
6
IPR059697
59,697
Protein dhr
Dhr
Family
80
false
false
This entry represents the Dhr protein found in bacteriophages. The prototype is from Escherichia phage 186, a 66 amino acid protein with a molecular weight of 7.5 kDa. The protein is also known as CP78 and is classified as an early protein expressed during the lytic cycle. Dhr is involved in the depression of host DNA ...
[]
[]
[]
0
[ "PFAM" ]
[ "PF26872" ]
[ "Phage_186_Dhr" ]
[ 80 ]
1
[]
[]
[]
0
[]
0
[ "PUB00162226" ]
[ "2704043" ]
[ "DNA replication studies with coliphage 186. II. Depression of host replication by a 186 gene." ]
[ 1989 ]
1
[]
[]
0
0
null
[ "Eganvirus", "Enterobacterales" ]
[ 4, 76 ]
2
[]
[]
0
true
Family
Protein dhr
Protein dhr
Dhr
1
IPR059699
59,699
YolB
YolB
Domain
73
false
false
This entry represents YolB proteins derived from SPbeta prophage and related bacteriophages. YolB is a small protein of approximately 118 amino acids found in the SPbeta prophage of Bacillus subtilis and related systems. The protein is found across 32 species including both bacteria and viruses, particularly in Bacilla...
[]
[]
[]
0
[ "PFAM" ]
[ "PF27433" ]
[ "YolB" ]
[ 73 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacillota", "Bacillus phage SPbeta" ]
[ 72, 1 ]
2
[]
[]
0
true
Domain
YolB
YolB
YolB
8
IPR059700
59,700
AF_2048, N-terminal domain
AF_2048_N
Domain
75
false
false
This entry represents the N-terminal domain of the AF_2048 uncharacterised membrane proteins found exclusively in archaea. This domain is found in Methanosarcinaceae, particularly Methanosarcina, and Archaeoglobaceae including Archaeoglobus. The full-length proteins are approximately 307 amino acids and contain predict...
[]
[]
[]
0
[ "PFAM" ]
[ "PF27367" ]
[ "AF_2048_N" ]
[ 75 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Methanobacteriota" ]
[ 75 ]
1
[]
[]
0
true
Domain
AF_2048, N-terminal domain
AF_2048, N-terminal domain
AF_2048_N
6
IPR059701
59,701
Flightin, C-terminal domain
Flightin_C
Domain
77
false
false
This entry represents the C-terminal domain of flightin. While the complete protein functions as a structural constituent of muscle with elasticity properties, the specific function of this C-terminal domain remains to be determined. Flightin is a myofibrillar protein found exclusively in the indirect flight muscles of...
[]
[]
[]
0
[ "PFAM" ]
[ "PF28577" ]
[ "Flightin_C" ]
[ 77 ]
1
[]
[]
[]
0
[ "8u8h" ]
1
[ "PUB00161963" ]
[ "8486738" ]
[ "Flightin, a novel myofibrillar protein of Drosophila stretch-activated muscles." ]
[ 1993 ]
1
[]
[]
0
0
null
[ "Neoptera" ]
[ 77 ]
1
[ "Drosophila melanogaster" ]
[ 2 ]
1
true
Domain
Flightin, C-terminal domain
Flightin, C-terminal domain
Flightin_C
7
IPR059702
59,702
ESX-1 scaffolding and assembly protein SaeC, N-terminal domain
SaeC_ESX1_N
Domain
73
false
false
This entry represents the N-terminal domain of the SaeC protein family, which functions as a scaffolding and assembly factor for the ESX-1 (ESAT-6 secretion system 1) type VII secretion system (T7SS) in mycobacteria. SaeC is involved in the assembly and polar localisation of the ESX-1 secretory apparatus, which exports...
[]
[]
[]
0
[ "PFAM" ]
[ "PF27062" ]
[ "SaeC_ESX1_N" ]
[ 73 ]
1
[]
[]
[]
0
[]
0
[ "PUB00161235" ]
[ "22233444" ]
[ "Polar assembly and scaffolding proteins of the virulence-associated ESX-1 secretory apparatus in mycobacteria." ]
[ 2012 ]
1
[]
[]
0
0
null
[ "Actinomycetes" ]
[ 73 ]
1
[]
[]
0
true
Domain
ESX-1 scaffolding and assembly protein SaeC, N-terminal domain
ESX-1 scaffolding and assembly protein SaeC, N-terminal domain
SaeC_ESX1_N
3
IPR059704
59,704
Y4bO, third domain
Y4bO_3rd
Domain
73
false
false
This entry represents the third domain of Y4bO, an uncharacterised protein from Sinorhizobium fredii. The protein is 606 amino acids in length and is encoded on the symbiotic plasmid pNGR234a. This domain is found in various bacterial species, predominantly in Pseudomonadati and Bacillati. The function of this domain r...
[]
[]
[]
0
[ "PFAM" ]
[ "PF27477" ]
[ "Y4bO_3rd" ]
[ 73 ]
1
[]
[]
[]
0
[]
0
[ "PUB00004254", "PUB00113962" ]
[ "9163424", "19376903" ]
[ "Molecular basis of symbiosis between Rhizobium and legumes.", "Rhizobium sp. strain NGR234 possesses a remarkable number of secretion systems." ]
[ 1997, 2009 ]
2
[]
[]
0
0
null
[ "Bacteria", "Ricinus communis" ]
[ 72, 1 ]
2
[]
[]
0
true
Domain
Y4bO, third domain
Y4bO, third domain
Y4bO_3rd
9
IPR059705
59,705
ARB_05566, C-terminal domain
ARB_05566_C
Domain
72
false
false
This entry represents the C-terminal in ARB_05566-like secreted proteins found in fungal species. The protein contains a signal peptide (residues 1-15) followed by a mature secreted protein of 175 residues. The representative protein from Arthroderma benhamiae has been identified by mass spectrometry and confirmed to b...
[]
[]
[]
0
[ "PFAM" ]
[ "PF28392" ]
[ "ARB_05566_C" ]
[ 72 ]
1
[]
[]
[]
0
[]
0
[ "PUB00150849" ]
[ "21919205" ]
[ "Identification of novel secreted proteases during extracellular proteolysis by dermatophytes at acidic pH." ]
[ 2011 ]
1
[]
[]
0
0
null
[ "leotiomyceta" ]
[ 72 ]
1
[]
[]
0
true
Domain
ARB_05566, C-terminal domain
ARB_05566, C-terminal domain
ARB_05566_C
8
IPR059706
59,706
Uncharacterized protein Gp1
Gp1
Family
69
false
false
This entry represents gene product 1 (Gp1) found in N4-like bacteriophages. Gp1 is an uncharacterised protein of 108 amino acids (12.2 kDa) located at the left end of the bacteriophage N4 genome. This entry also includes bacterial proteins.
[]
[]
[]
0
[ "PFAM" ]
[ "PF26891" ]
[ "Phage_N4_Gp1" ]
[ 69 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Pseudomonadota", "Viruses" ]
[ 11, 58 ]
2
[]
[]
0
true
Family
Uncharacterized protein Gp1
Uncharacterized protein Gp1
Gp1
9
IPR059708
59,708
AF_1994, N-terminal domain
AF_1994_N
Domain
67
false
false
This entry represents the N-terminal domain of the AF_1994 proteins found in bacteria. The domain is found in diverse bacterial lineages including Flavobacteriaceae, Clostridiaceae, and Chitinophagaceae. The full-length proteins are approximately 236 amino acids and contain predicted signal peptides, indicating they ar...
[]
[]
[]
0
[ "PFAM" ]
[ "PF27311" ]
[ "AF_1994_N" ]
[ 67 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria", "Methanobacteriota", "marine metagenome" ]
[ 51, 13, 3 ]
3
[]
[]
0
true
Domain
AF_1994, N-terminal domain
AF_1994, N-terminal domain
AF_1994_N
2
IPR059709
59,709
Y4mA, N-terminal domain
Y4mA_N
Domain
67
false
false
This entry represents the N-terminal domain of y4mA proteins. The domain is found in bacteria, predominantly in Alphaproteobacteria with representatives in Hyphomicrobiales and Rhodobacterales orders. The function of this domain remains to be determined.
[]
[]
[]
0
[ "PFAM" ]
[ "PF27403" ]
[ "Y4mA_N" ]
[ 67 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Alphaproteobacteria", "marine sediment metagenome" ]
[ 66, 1 ]
2
[]
[]
0
true
Domain
Y4mA, N-terminal domain
Y4mA, N-terminal domain
Y4mA_N
5
IPR059710
59,710
Gene 75 protein
Gp75
Family
66
false
false
This entry represents gene 75 protein (Gp75) found in mycobacteriophages. The prototype is from Mycobacterium phage L5, a small protein of 43 amino acids with a molecular weight of 4.9 kDa. Members of this family are found in bacteriophages that infect Mycobacterium species. The function of this protein remains unknown...
[]
[]
[]
0
[ "PFAM" ]
[ "PF26828" ]
[ "Phage_gp75" ]
[ 66 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Caudoviricetes", "Mycolicibacterium" ]
[ 64, 2 ]
2
[]
[]
0
true
Family
Gene 75 protein
Gene 75 protein
Gp75
3
IPR059711
59,711
TP_0021, N-terminal domain
TP_0021_N
Domain
65
false
false
This entry represents the N-terminal domain of TP_0021 proteins. This domain adopts a helix-extended loop-helix (HeH) fold structure. The specific function of this domain remains to be determined. This domain can be found in predicted Helicase XPB/Ssl2 N-terminal domain-containing protein.
[]
[]
[]
0
[ "PFAM" ]
[ "PF27388" ]
[ "TP_0021_N" ]
[ 65 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Spirochaetia", "bioreactor metagenome" ]
[ 64, 1 ]
2
[]
[]
0
true
Domain
TP_0021, N-terminal domain
TP_0021, N-terminal domain
TP_0021_N
7
IPR059712
59,712
AF_1447
AF_1447
Domain
66
false
false
This entry represents the AF_1447 small uncharacterised proteins found predominantly in bacteria with some archaeal members. The domain is found mainly in Bacteroidota, particularly Flavobacteriaceae and Flavobacterium, with additional members in Bacillota and some archaea. The proteins are approximately 81 amino acids...
[]
[]
[]
0
[ "PFAM" ]
[ "PF27350" ]
[ "AF_1447" ]
[ 66 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria", "Methanobacteriota", "ecological metagenomes" ]
[ 51, 6, 9 ]
3
[]
[]
0
true
Domain
AF_1447
AF_1447
AF_1447
8
IPR059713
59,713
Uncharacterised protein YtsF, C-terminal domain
YtsF_C
Domain
64
false
false
This entry represents the C-terminal domain of uncharacterised proteins found in Spiroplasma, Mycoplasma and Mesoplasma species. The prototype protein YtsF from Spiroplasma citri is located in the rpsB/tsf/x operon downstream of the elongation factor Ts gene [ ]. The protein is approximately 211 amino acids in length a...
[]
[]
[]
0
[ "PFAM" ]
[ "PF27468" ]
[ "YtsF" ]
[ 64 ]
1
[]
[]
[]
0
[]
0
[ "PUB00162427" ]
[ "2139649" ]
[ "Organization and nucleotide sequences of the Spiroplasma citri genes for ribosomal protein S2, elongation factor Ts, spiralin, phosphofructokinase, pyruvate kinase, and an unidentified protein." ]
[ 1990 ]
1
[]
[]
0
0
null
[ "Mollicutes" ]
[ 64 ]
1
[]
[]
0
true
Domain
Uncharacterised protein YtsF, C-terminal domain
Uncharacterised protein YtsF, C-terminal domain
YtsF_C
9
IPR059714
59,714
PXO2-26
pXO2_26
Domain
66
false
false
This entry represents protein pXO2-26 found in Bacillus anthracis plasmid pXO2. This protein is an uncharacterised membrane protein of 130 amino acids that contains a predicted transmembrane helix. The protein is encoded on plasmid pXO2, one of the virulence plasmids of Bacillus anthracis. The C-terminal part of the pr...
[]
[]
[]
0
[ "PFAM" ]
[ "PF27053" ]
[ "B_anthracis_pXO2_26" ]
[ 66 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacillota" ]
[ 66 ]
1
[]
[]
0
true
Domain
PXO2-26
PXO2-26
pXO2_26
7
IPR059715
59,715
Probable protease Gilli_2517, N-terminal domain
Gilli_2517_N
Domain
64
false
false
This entry represents the N-terminal in Probable protease Gilli_2517. This protein is part of a family of bacterial proteases that specifically cleave bacterial gasdermins (bGSDMs). These proteases are typically found adjacent to bacterial gasdermin genes and function as dedicated enzymes for gasdermin activation. The ...
[]
[]
[]
0
[ "PFAM" ]
[ "PF27061" ]
[ "Gasdermin_protease" ]
[ 64 ]
1
[]
[]
[]
0
[]
0
[ "PUB00100796" ]
[ "35025633" ]
[ "Bacterial gasdermins reveal an ancient mechanism of cell death." ]
[ 2022 ]
1
[]
[]
0
0
null
[ "Bacteria" ]
[ 64 ]
1
[]
[]
0
true
Domain
Probable protease Gilli_2517, N-terminal domain
Probable protease Gilli_2517, N-terminal domain
Gilli_2517_N
4
IPR059716
59,716
AF_0896, middle domain
AF_0896_M
Domain
63
false
false
This entry represents the middle domain of AF_0896 and related uncharacterised proteins found in archaea. This domain is found predominantly in halophilic archaea including Natrialbaceae and Haloferacaceae, with some members in Nitrososphaeraceae. The full-length proteins are approximately 369 amino acids and contain t...
[]
[]
[]
0
[ "PFAM" ]
[ "PF27341" ]
[ "AF_0896_M" ]
[ 63 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Archaea", "marine sediment metagenome" ]
[ 62, 1 ]
2
[]
[]
0
true
Domain
AF_0896, middle domain
AF_0896, middle domain
AF_0896_M
3
IPR059717
59,717
TP_0983
TP_0983
Domain
64
false
false
This entry represents a domain found in Uncharacterized protein TP_0983. The domain is found predominantly in Spirochaetota, with representatives in Treponema and Spirochaeta genera within the Spirochaetales order. The domain is present in proteins that contain an N-terminal signal peptide. The function of this domain ...
[]
[]
[]
0
[ "PFAM" ]
[ "PF27391" ]
[ "TP_0983" ]
[ 64 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Spirochaetia", "marine sediment metagenome" ]
[ 62, 2 ]
2
[]
[]
0
true
Domain
TP_0983
TP_0983
TP_0983
8
IPR059718
59,718
TP_0437
TP_0437
Domain
60
false
false
This entry represents a domain found in Uncharacterized protein TP_0437. The domain is found predominantly in Spirochaetota, with representatives in Treponema and Spirochaeta genera within Spirochaetales order. The function of this domain remains to be determined.
[]
[]
[]
0
[ "PFAM" ]
[ "PF27399" ]
[ "TP_0437" ]
[ 60 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Spirochaetia" ]
[ 60 ]
1
[]
[]
0
true
Domain
TP_0437
TP_0437
TP_0437
8
IPR059719
59,719
BioS, helical domain
BioS_helical
Domain
60
false
false
This entry represents the helical-like domain found in BioS, a biotin transport regulator from Sinorhizobium meliloti [ , ]. This domain is found predominantly in Alphaproteobacteria, particularly within Hyphomicrobiales including the Rhizobiaceae. While BioS is involved in biotin transport regulation, the specific fun...
[]
[]
[]
0
[ "PFAM" ]
[ "PF27488" ]
[ "BioS" ]
[ 60 ]
1
[]
[]
[]
0
[]
0
[ "PUB00161833", "PUB00161834" ]
[ "9304864", "10494632" ]
[ "A biotin-regulated locus, bioS, in a possible survival operon of Rhizobium meliloti.", "BioS, a biotin-induced, stationary-phase, and possible LysR-type regulator in Sinorhizobium meliloti." ]
[ 1997, 1999 ]
2
[]
[]
0
0
null
[ "Pseudomonadota" ]
[ 60 ]
1
[]
[]
0
true
Domain
BioS, helical domain
BioS, helical domain
BioS_helical
4
IPR059720
59,720
Y06R
Y06R
Family
58
false
false
This entry represents protein Y06R found in bacteriophages. The prototype is from bacteriophage T4, a 111 amino acid protein with a molecular weight of 13.1 kDa located in the e-segB intergenic region. The protein is also known as e.7 or msp2 and is found in the region between lysozyme and the tRNA genes. The function ...
[]
[]
[]
0
[ "PFAM" ]
[ "PF26875" ]
[ "Phage_T4_Y06R" ]
[ 58 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Viruses" ]
[ 58 ]
1
[]
[]
0
true
Family
Y06R
Y06R
Y06R
2
IPR059721
59,721
Eai protein
Eai
Family
58
false
false
This entry represents the Eai protein found in bacteriophages. The prototype is from Salmonella phage P22, a 64 amino acid protein with a molecular weight of 7.0 kDa. The protein was identified in studies of phage P22 int gene regulation and remains uncharacterised. The function of this protein is unknown. This entry a...
[]
[]
[]
0
[ "PFAM" ]
[ "PF26866" ]
[ "Phage_P22_Eai" ]
[ 58 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Caudoviricetes", "Enterobacterales" ]
[ 8, 50 ]
2
[]
[]
0
true
Family
Eai protein
Eai protein
Eai
8
IPR059722
59,722
Coiled-coil domain-containing protein ORF29
ORF29_CC
Domain
58
false
false
This entry represents ORF29 found in bacteriophages. The prototype is from Helicobacter pylori bacteriophage KHP30, a 271 amino acid protein with a molecular weight of 30.3 kDa. The protein contains a predicted coiled-coil domain and has been identified by mass spectrometry in phage particles, indicating it is a struct...
[]
[]
[]
0
[ "PFAM" ]
[ "PF26853" ]
[ "Phage_ORF29_CC" ]
[ 58 ]
1
[]
[]
[]
0
[]
0
[ "PUB00089799" ]
[ "23475617" ]
[ "Characterization of Helicobacter pylori bacteriophage KHP30." ]
[ 2013 ]
1
[]
[]
0
0
null
[ "Campylobacterales", "Schmidvirus" ]
[ 55, 3 ]
2
[]
[]
0
true
Domain
Coiled-coil domain-containing protein ORF29
Coiled-coil domain-containing protein ORF29
ORF29_CC
4
IPR059723
59,723
Internal protein III
IpIII
Family
57
false
false
This entry represents internal protein III (IpIII) found in bacteriophages. The prototype is from bacteriophage T4, a 193-amino-acid protein with a molecular weight of 21.7 kDa. The protein is synthesised as a precursor with an N-terminal propeptide that is cleaved by prohead core protease GP21 during phage head matura...
[]
[]
[]
0
[ "PFAM" ]
[ "PF26861" ]
[ "Phage_T4_IpIII" ]
[ 57 ]
1
[]
[]
[]
0
[]
0
[ "PUB00162545", "PUB00162546" ]
[ "1069310", "24113" ]
[ "Protein cleavage during virus assembly: a novel specificity of assembly dependent cleavage in bacteriophage T4.", "Teeth modifications and their socio-economic and political significance among some peoples of the world and early Filipinos." ]
[ 1976, 1975 ]
2
[]
[]
0
0
null
[ "Caudoviricetes" ]
[ 57 ]
1
[]
[]
0
true
Family
Internal protein III
Internal protein III
IpIII
6
IPR059724
59,724
YmgI-like domain
YmgI
Domain
61
false
false
This entry represents the YmgI domain found in bacteria. This domain is found in Escherichia coli (gene ymgI, locus b4593) and related bacterial proteins. The function of this domain remains to be determined.
[]
[]
[]
0
[ "PFAM" ]
[ "PF28591" ]
[ "YmgI" ]
[ 61 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Enterobacteriaceae" ]
[ 61 ]
1
[ "Escherichia coli (strain K12)" ]
[ 1 ]
1
true
Domain
YmgI-like domain
YmgI-like domain
YmgI
3
IPR059725
59,725
TP_0813, N-terminal domain
TP_0813_N
Domain
56
false
false
This entry represents the N-terminal domain of TP_0813 proteins found primarily in Treponema and related spirochaetes. This domain forms a helical bundle structure. The protein is found across the Spirochaetota phylum within the Spirochaetales order. TP_0813 proteins are particularly abundant in Treponema species. The ...
[]
[]
[]
0
[ "PFAM" ]
[ "PF27435" ]
[ "TP_0813_N" ]
[ 56 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Pseudomonadati", "ecological metagenomes" ]
[ 54, 2 ]
2
[]
[]
0
true
Domain
TP_0813, N-terminal domain
TP_0813, N-terminal domain
TP_0813_N
2
IPR059726
59,726
TP_0927
TP_0927
Domain
55
false
false
This entry represents TP_0927 proteins found primarily in Treponema and related spirochaetes. The protein is found mainly in Spirochaetota phylum within the Spirochaetales order. TP_0927 proteins are particularly abundant in Treponema species. The function of this protein remains to be determined. This proteins contain...
[]
[]
[]
0
[ "PFAM" ]
[ "PF27440" ]
[ "TP_0927" ]
[ 55 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Spirochaetia" ]
[ 55 ]
1
[]
[]
0
true
Domain
TP_0927
TP_0927
TP_0927
3
IPR059727
59,727
Putative rubredoxin, C-terminal domain
RdxA_C
Domain
54
false
false
This entry represents the C-terminal domain in putative rubredoxin from Methanothermobacter thermautotrophicus and related proteins found in archaea and bacteria. This domain is found predominantly in methanogenic archaea including Methanobacteriaceae and Methanobacterium, with some members in sulphate-reducing bacteri...
[]
[]
[]
0
[ "PFAM" ]
[ "PF27323" ]
[ "RdxA_C" ]
[ 54 ]
1
[]
[]
[]
0
[]
0
[ "PUB00042737" ]
[ "7649162" ]
[ "Characterization of a 45-kDa flavoprotein and evidence for a rubredoxin, two proteins that could participate in electron transport from H2 to CO2 in methanogenesis in Methanobacterium thermoautotrophicum." ]
[ 1995 ]
1
[]
[]
0
0
null
[ "Bacteria", "Methanobacteriota", "marine sediment metagenome" ]
[ 15, 37, 2 ]
3
[]
[]
0
true
Domain
Putative rubredoxin, C-terminal domain
Putative rubredoxin, C-terminal domain
RdxA_C
8
IPR059728
59,728
AF_2379
AF_2379
Domain
56
false
false
This entry represents the AF_2379 small uncharacterised proteins found in sulphate-reducing bacteria and archaea. The family is predominantly found in Thermodesulfobacteriota, particularly in Desulfobacteraceae, Desulfosarcinaceae, and Desulfococcaceae, with some members in Archaeoglobaceae. The function of this protei...
[]
[]
[]
0
[ "PFAM" ]
[ "PF27306" ]
[ "AF_2379" ]
[ 56 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria", "Methanobacteriota", "marine sediment metagenome" ]
[ 30, 16, 10 ]
3
[]
[]
0
true
Domain
AF_2379
AF_2379
AF_2379
5
IPR059729
59,729
YonJ, middle domain
YonJ_middle
Domain
55
false
false
This entry represents the middle coiled-coil domain of uncharacterised YonJ proteins found in bacteria and viruses. The full-length proteins are distributed across both Bacillati and viruses, including members from Paenibacillus species and Spbetavirus. Members include YonJ from Bacillus subtilis, which is derived from...
[]
[]
[]
0
[ "PFAM" ]
[ "PF27387" ]
[ "YonJ_CC" ]
[ 55 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacillota", "Viruses" ]
[ 42, 13 ]
2
[]
[]
0
true
Domain
YonJ, middle domain
YonJ, middle domain
YonJ_middle
4
IPR059730
59,730
RepA, N-terminal domain
WHD_RepA_N
Domain
52
false
false
This entry represents the N-terminal winged helix-turn-helix (HTH) domain found in plasmid replication initiator proteins of the RepA family. This domain is found in proteins from Bacillales and related Bacillota. The exemplar RepA protein from Bacillus subtilis plasmid pRAT11 is a 396 amino acid protein involved in pl...
[]
[]
[]
0
[ "PFAM" ]
[ "PF27612" ]
[ "WHD_RepA_N" ]
[ 52 ]
1
[]
[]
[]
0
[]
0
[ "PUB00009486" ]
[ "3041379" ]
[ "RepA protein- and oriR-dependent initiation of R1 plasmid replication: identification of a rho-dependent transcription terminator required for cis-action of repA protein." ]
[ 1988 ]
1
[]
[]
0
0
null
[ "Bacillota", "Rhizophagus irregularis (strain DAOM 197198w)" ]
[ 51, 1 ]
2
[]
[]
0
true
Domain
RepA, N-terminal domain
RepA, N-terminal domain
WHD_RepA_N
7
IPR059731
59,731
TP_0679
TP_0679
Domain
51
false
false
This entry represents TP_0679 membrane proteins found primarily in Treponema and related spirochaetes. TP_0679 is a small membrane protein of approximately 105 amino acids that contains three predicted transmembrane helical regions. The protein forms a helical bundle structure and is predicted to be localised to the ce...
[]
[]
[]
0
[ "PFAM" ]
[ "PF27420" ]
[ "TP_0679" ]
[ 51 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Spirochaetia" ]
[ 51 ]
1
[]
[]
0
true
Domain
TP_0679
TP_0679
TP_0679
7
IPR059732
59,732
TP_0183, C-terminal
TP_0183_C
Domain
50
false
false
This entry represents the C-terminal domain of TP_0183 proteins found primarily in Treponema and related spirochaetes. This domain adopts an avidin-like fold structure. The function of this domain remains to be determined. TP_0183 is a protein of approximately 281 amino acids that is processed from a precursor containi...
[]
[]
[]
0
[ "PFAM" ]
[ "PF27487" ]
[ "TP_0183_C" ]
[ 50 ]
1
[]
[]
[]
0
[]
0
[ "PUB00162494" ]
[ "18509523" ]
[ "The binary protein interactome of Treponema pallidum--the syphilis spirochete." ]
[ 2008 ]
1
[]
[]
0
0
null
[ "Spirochaetia" ]
[ 50 ]
1
[]
[]
0
true
Domain
TP_0183, C-terminal
TP_0183, C-terminal
TP_0183_C
9
IPR059733
59,733
Protein 0.6
0_6
Family
51
false
false
This entry represents protein 0.6 found in bacteriophages. The prototype is from bacteriophage T7, which exists as two forms due to frameshifting: protein 0.6A (53 amino acids) and protein 0.6B (111 amino acids, 13.2 kDa). Protein 0.6B results from a frameshift that occurs prior to the TGA stop codon of 0.6A. The prote...
[]
[]
[]
0
[ "PFAM" ]
[ "PF26851" ]
[ "Phage_T7_0_6" ]
[ 51 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Caudoviricetes" ]
[ 51 ]
1
[]
[]
0
true
Family
Protein 0.6
Protein 0.6
0_6
4
IPR059734
59,734
YorE
YorE
Domain
52
false
false
This entry represents a domain covering the whole length of YorE, an uncharacterised protein from the SPbeta prophage of Bacillus subtilis. The protein is 123 amino acids in length and adopts a YaeB-like fold. YorE is found predominantly in bacteriophages, particularly Spbetavirus within Caudoviricetes, as well as in b...
[]
[]
[]
0
[ "PFAM" ]
[ "PF27492" ]
[ "YorE" ]
[ 52 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacillota", "Bacillus phage SPbeta" ]
[ 51, 1 ]
2
[]
[]
0
true
Domain
YorE
YorE
YorE
9
IPR059735
59,735
STK_12200
STK_12200
Domain
48
false
false
This entry represents the N-terminal in STK_12200 and related uncharacterised proteins found exclusively in thermoacidophilic archaea. This domain is found in Thermoproteota, particularly Sulfolobaceae including Sulfurisphaera, Acidianus, and Metallosphaera. The proteins are approximately 163 amino acids in length and ...
[]
[]
[]
0
[ "PFAM" ]
[ "PF27373" ]
[ "STK_12200" ]
[ 48 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Sulfolobaceae" ]
[ 48 ]
1
[]
[]
0
true
Domain
STK_12200
STK_12200
STK_12200
4
IPR059736
59,736
MJECL32
MJECL32
Domain
49
false
false
This entry represents the N-terminal in MJECL32 found in uncharacterised proteins in archaea and bacteria. This domain is found in diverse lineages including Methanocaldococcaceae, Haloferacaceae, and Halobacteriales in archaea, and Bacillaceae in bacteria. The function of this domain remains to be determined.
[]
[]
[]
0
[ "PFAM" ]
[ "PF27326" ]
[ "MJECL32" ]
[ 49 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Archaea", "Bacteria", "marine sediment metagenome" ]
[ 28, 20, 1 ]
3
[]
[]
0
true
Domain
MJECL32
MJECL32
MJECL32
7
IPR059737
59,737
MJ0788
MJ0788
Domain
46
false
false
This entry represents MJ0788 and related small uncharacterised proteins found exclusively in methanogenic archaea. The family is found across various methanogenic lineages including Methanobacteriaceae, Methanobrevibacter, Methanobacterium, Methanomicrobiaceae, and Methanocaldococcaceae. The proteins are approximately ...
[]
[]
[]
0
[ "PFAM" ]
[ "PF27370" ]
[ "MJ0788" ]
[ 46 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Candidatus Zambryskibacteria bacterium CG10_big_fil_rev_8_21_14_0_10_34_34", "Methanobacteriota", "Methanocaldococcus fervens tailed virus 1", "bioreactor metagenome" ]
[ 1, 43, 1, 1 ]
4
[]
[]
0
true
Domain
MJ0788
MJ0788
MJ0788
3
IPR059738
59,738
YonG, C-terminal domain
YonG_C
Domain
48
false
false
This entry represents the C-terminal domain of YonG proteins found in bacteria and viruses. YonG proteins are derived from prophage elements such as SPbeta in Bacillus subtilis. Members of this domain are also found in Spbetavirus. The specific function of this C-terminal domain remains to be determined.
[]
[]
[]
0
[ "PFAM" ]
[ "PF27316" ]
[ "YonG_C" ]
[ 48 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacillota", "Caudoviricetes" ]
[ 43, 5 ]
2
[]
[]
0
true
Domain
YonG, C-terminal domain
YonG, C-terminal domain
YonG_C
2
IPR059739
59,739
PIF6, PH domain
PH_PIF6
Domain
47
false
false
This entry represents the N-terminal PH domain found in the PIF6 protein , which is a DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of genome stability.
[]
[]
[]
0
[ "PFAM" ]
[ "PF26661" ]
[ "PH_PIF6" ]
[ 47 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Euglenozoa" ]
[ 47 ]
1
[]
[]
0
true
Domain
PIF6, PH domain
PIF6, PH domain
PH_PIF6
3
IPR059740
59,740
Internal protein II
IpII
Family
42
false
false
This entry represents internal protein II (IpII) found in bacteriophages. The prototype is from bacteriophage T4, a 100 amino acid protein with a molecular weight of 11.1 kDa. The protein is synthesised as a precursor with an N-terminal propeptide that is cleaved by prohead core protease GP21 during phage maturation. I...
[]
[]
[]
0
[ "PFAM" ]
[ "PF26874" ]
[ "Phage_T4_IpII" ]
[ 42 ]
1
[]
[]
[]
0
[]
0
[ "PUB00162243" ]
[ "1271467" ]
[ "Primary structure of bacteriophage T4 internal protein II and characterization of the cleavage upon phage maturation." ]
[ 1976 ]
1
[]
[]
0
0
null
[ "Viruses" ]
[ 42 ]
1
[]
[]
0
true
Family
Internal protein II
Internal protein II
IpII
1
IPR059741
59,741
TP_0747, N-terminal domain
TP_0747_N
Domain
40
false
false
This entry represents the N-terminal domain of TP_0747, an uncharacterised protein from Treponema pallidum. TP_0747 is 344 amino acids in length and contains a disordered region. This domain is found predominantly in Spirochaetota, particularly within Spirochaetales including Treponemataceae, Spirochaetaceae and Brezna...
[]
[]
[]
0
[ "PFAM" ]
[ "PF27497" ]
[ "TP_0747_N" ]
[ 40 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Potamilus streckersoni", "Spirochaetia", "marine sediment metagenome" ]
[ 1, 38, 1 ]
3
[]
[]
0
true
Domain
TP_0747, N-terminal domain
TP_0747, N-terminal domain
TP_0747_N
3
IPR059742
59,742
Superinfection exclusion protein A
SIEA
Family
35
false
false
The Superinfection exclusion protein A family is involved in preventing the entry of phage DNA into the cytoplasm by blocking its transfer across the inner membrane. This mechanism provides protection against superinfection by phages of the same family and also against DNA from other phages [ ]. This entry also include...
[]
[]
[]
0
[ "PFAM" ]
[ "PF26849" ]
[ "SIEA" ]
[ 35 ]
1
[]
[]
[]
0
[]
0
[ "PUB00162295" ]
[ "7768804" ]
[ "The superinfection exclusion gene (sieA) of bacteriophage P22: identification and overexpression of the gene and localization of the gene product." ]
[ 1995 ]
1
[]
[]
0
0
null
[ "Lederbergvirus", "Pseudomonadota" ]
[ 5, 30 ]
2
[]
[]
0
true
Family
Superinfection exclusion protein A
Superinfection exclusion protein A
SIEA
1
IPR059743
59,743
Beta-methylindole-3-pyruvate reductase, C-terminal domain
Ind2_C
Domain
43
false
false
This entry represents the C-terminal domain of beta-methylindole- 3-pyruvate reductase (Ind2) found in Streptomyces species and related actinobacteria. This domain forms part of an enzyme involved in indolmycin biosynthesis, an antibiotic that inhibits bacterial tryptophan-tRNA synthetases [ ]. The complete enzyme cata...
[]
[]
[]
0
[ "PFAM" ]
[ "PF27054" ]
[ "Beta_methylindole_red_C" ]
[ 43 ]
1
[]
[]
[]
0
[]
0
[ "PUB00161827" ]
[ "25730866" ]
[ "In vitro reconstitution of indolmycin biosynthesis reveals the molecular basis of oxazolinone assembly." ]
[ 2015 ]
1
[]
[]
0
0
null
[ "Bacteria", "Candidatus Methanogaster sp. ANME-2c ERB4", "Sar", "ecological metagenomes" ]
[ 35, 1, 4, 3 ]
4
[]
[]
0
true
Domain
Beta-methylindole-3-pyruvate reductase, C-terminal domain
Beta-methylindole-3-pyruvate reductase, C-terminal domain
Ind2_C
5
IPR059744
59,744
Putative protein p49
Put_P49
Family
33
false
false
This entry represents protein p49 found in APSE-1-like bacteriophages. Protein p49 is an uncharacterised protein of 90 amino acids (10.5 kDa) found in bacteriophage APSE-1 that infects the secondary endosymbiont of Acyrthosiphon pisum [ ].
[]
[]
[]
0
[ "PFAM" ]
[ "PF26917" ]
[ "Phage_APSE1_p49" ]
[ 33 ]
1
[]
[]
[]
0
[]
0
[ "PUB00162547" ]
[ "10489345" ]
[ "Isolation and characterization of APSE-1, a bacteriophage infecting the secondary endosymbiont of Acyrthosiphon pisum." ]
[ 1999 ]
1
[]
[]
0
0
null
[ "Aphis craccivora", "Enterobacterales", "Sendosyvirus" ]
[ 1, 30, 2 ]
3
[]
[]
0
true
Family
Putative protein p49
Putative protein p49
Put_P49
5
IPR059745
59,745
Probable regulatory protein N
Prob_reg_N
Family
33
false
false
This entry represents the N antitermination protein found in bacteriophages. The prototype is from bacteriophage phi-80, a 98 amino acid protein with a molecular weight of 11.7 kDa. The N protein functions as a transcriptional antitermination factor, allowing RNA polymerase to read through transcription termination sig...
[]
[]
[]
0
[ "PFAM" ]
[ "PF26859" ]
[ "Phage_N_antitermin" ]
[ 33 ]
1
[]
[]
[]
0
[]
0
[ "PUB00162231" ]
[ "4065570" ]
[ "Characterization and sequencing of the region containing gene N, the nutL site and tL1 terminator of bacteriophage phi 80." ]
[ 1985 ]
1
[]
[]
0
0
null
[ "Bacteria", "Caudoviricetes" ]
[ 28, 5 ]
2
[]
[]
0
true
Family
Probable regulatory protein N
Probable regulatory protein N
Prob_reg_N
7
IPR059746
59,746
SPbeta prophage YomF protein, middle domain
YomF_M
Domain
30
false
false
This entry represents the middle domain in YomF. The function of this domain remains unknown. YomF is an uncharacterised protein encoded by the SPbeta prophage in Bacillus subtilis. This protein contains an N-terminal domain , middle domain and a C-terminal domain .
[]
[]
[]
0
[ "PFAM" ]
[ "PF27068" ]
[ "YomF_M" ]
[ 30 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacillus", "Bacillus phage SPbeta" ]
[ 29, 1 ]
2
[]
[]
0
true
Domain
SPbeta prophage YomF protein, middle domain
SPbeta prophage YomF protein, middle domain
YomF_M
4
IPR059747
59,747
Gene 45 protein
Gp45
Domain
28
false
false
This entry represents the gene 45 protein found in L5-like mycobacteriophages. Gene 45 protein is an uncharacterised protein of 97 amino acids (10.7 kDa) found in Mycobacterium phage L5.
[]
[]
[]
0
[ "PFAM" ]
[ "PF26905" ]
[ "Phage_L5_Gp45" ]
[ 28 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Caudoviricetes", "Mycolicibacterium" ]
[ 26, 2 ]
2
[]
[]
0
true
Domain
Gene 45 protein
Gene 45 protein
Gp45
7
IPR059748
59,748
UL148B
UL148B
Family
27
false
false
This entry represents protein UL148B found in human cytomegalovirus. UL148B is an uncharacterised membrane protein of 80 amino acids (8.9 kDa) that localises to the host membrane. The protein contains a predicted transmembrane helix (residues 10-30).
[]
[]
[]
0
[ "PFAM" ]
[ "PF26987" ]
[ "HCMV_UL148B" ]
[ 27 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Cytomegalovirus" ]
[ 27 ]
1
[]
[]
0
true
Family
UL148B
UL148B
UL148B
4
IPR059749
59,749
MJ1491, transmembrane domain
MJ1491_TM
Domain
31
false
false
This entry represents the MJ1491 transmembrane domain found in uncharacterised membrane proteins in archaea and bacteria. This domain is found predominantly in methanogenic archaea including Methanocaldococcaceae and Methanococcales, with some bacterial members. The domain contains three predicted transmembrane helices...
[]
[]
[]
0
[ "PFAM" ]
[ "PF27404" ]
[ "MJ1491" ]
[ 31 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria", "Methanobacteriota", "marine sediment metagenome" ]
[ 8, 22, 1 ]
3
[]
[]
0
true
Domain
MJ1491, transmembrane domain
MJ1491, transmembrane domain
MJ1491_TM
9
IPR059750
59,750
AF_1283 family
AF_1283
Family
26
false
false
This entry represents the AF_1283 family of small membrane proteins found exclusively in thermophilic archaea. The family is found in Archaeoglobaceae, particularly Archaeoglobus and Ferroglobus, and Ferroplasmaceae. The proteins are approximately 100 amino acids in length and contain three predicted transmembrane heli...
[]
[]
[]
0
[ "PFAM" ]
[ "PF27384" ]
[ "AF_1283" ]
[ 26 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Methanobacteriati" ]
[ 26 ]
1
[]
[]
0
true
Family
AF_1283 family
AF_1283 family
AF_1283
2
IPR059751
59,751
AF_2141 family
AF_2141
Family
27
false
false
This entry represents the AF_2141 family of uncharacterised proteins found predominantly in archaea with some bacterial members. The family is found mainly in Archaeoglobaceae, particularly Archaeoglobus, with additional members in candidate division MSBL1 and some Syntrophobacterales. The proteins are approximately 22...
[]
[]
[]
0
[ "PFAM" ]
[ "PF27374" ]
[ "AF_2141" ]
[ 27 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria", "Methanobacteriota", "marine sediment metagenome" ]
[ 4, 21, 2 ]
3
[]
[]
0
true
Family
AF_2141 family
AF_2141 family
AF_2141
7
IPR059752
59,752
AF_0059 family
AF_0059
Family
25
false
false
This entry represents the AF_0059 family of uncharacterised proteins found exclusively in archaea. The family is found predominantly in Archaeoglobaceae, particularly Archaeoglobus, with additional members in candidate division MSBL1. The proteins are approximately 134 amino acids in length. The function of this protei...
[]
[]
[]
0
[ "PFAM" ]
[ "PF27352" ]
[ "AF_0059" ]
[ 25 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Methanobacteriota" ]
[ 25 ]
1
[]
[]
0
true
Family
AF_0059 family
AF_0059 family
AF_0059
2
IPR059753
59,753
Bacteriophage T7 protein 0.5
Gp0_5
Family
24
false
false
This entry represents the bacteriophage T7 protein 0.5 (Gp0.5) family, a small membrane protein found in T7 and related phages. The protein is synthesised as a 47-amino-acid precursor with an N-terminal signal peptide (residues 1-23) that is cleaved to produce the mature 24-amino-acid protein. The mature protein contai...
[]
[]
[]
0
[ "PFAM" ]
[ "PF26813" ]
[ "Gp0_5" ]
[ 24 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Caudoviricetes" ]
[ 24 ]
1
[]
[]
0
true
Family
Bacteriophage T7 protein 0.5
Bacteriophage T7 protein 0.5
Gp0_5
8
IPR059755
59,755
AF0772-like protein C-terminal domain
AF0772_C
Domain
21
false
false
This entry represents the C-terminal domain of AF0772-like proteins found in archaea. These proteins are found in the Archaeoglobi class, including Archaeoglobus, Geoglobus, and Ferroglobus species, as well as some methanogens. The function of this domain remains to be determined.
[]
[]
[]
0
[ "PFAM" ]
[ "PF27411" ]
[ "AF0772_C" ]
[ 21 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Methanobacteriota" ]
[ 21 ]
1
[]
[]
0
true
Domain
AF0772-like protein C-terminal domain
AF0772-like protein C-terminal domain
AF0772_C
5
IPR059757
59,757
Aq_420-like protein
Aq_420
Family
19
false
false
This entry represents a family of small uncharacterised bacterial proteins. The prototype member aq_420 from Aquifex aeolicus strain VF5 is a 115 amino acid protein of unknown function. A. aeolicus is a hyperthermophilic bacterium that grows optimally at 85-95 degrees C, suggesting this protein family may be adapted to...
[]
[]
[]
0
[ "PFAM" ]
[ "PF27093" ]
[ "Aq_420" ]
[ 19 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Aquificales" ]
[ 19 ]
1
[]
[]
0
true
Family
Aq_420-like protein
Aq_420-like protein
Aq_420
1
IPR059758
59,758
AF0631-like, N-terminal beta-barrel domain
AF0631_N
Domain
19
false
false
This entry represents the N-terminal domain of AF0631-like proteins found in archaea and bacteria. This domain forms a seven-stranded β-barrel structure of approximately 138 amino acids. The family is found predominantly in Archaeoglobi, including Archaeoglobus, Geoglobus, and Ferroglobus species, with additional membe...
[]
[]
[]
0
[ "PFAM" ]
[ "PF27425" ]
[ "AF0631_N" ]
[ 19 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Archaea", "Breznakiellaceae" ]
[ 16, 3 ]
2
[]
[]
0
true
Domain
AF0631-like, N-terminal beta-barrel domain
AF0631-like, N-terminal beta-barrel domain
AF0631_N
2
IPR059759
59,759
Phage T7 protein 1.5
Phage_T7_1_5
Family
18
false
false
This entry represents protein 1.5 found in bacteriophages. The prototype is from bacteriophage T7, a small 29 amino acid protein with a molecular weight of 3.2 kDa. The protein is also known as gene product 1.5 (Gp1.5) and contains a hydrophobic N-terminal region suggesting potential membrane association. The function ...
[]
[]
[]
0
[ "PFAM" ]
[ "PF26858" ]
[ "Phage_T7_1_5" ]
[ 18 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Caudoviricetes" ]
[ 18 ]
1
[]
[]
0
true
Family
Phage T7 protein 1.5
Phage T7 protein 1.5
Phage_T7_1_5
6
IPR059760
59,760
Mycobacterium phage L5 gene 74 protein
Phage_L5_Gp74
Family
18
false
false
This entry represents the gene 74 protein family found in L5-like mycobacteriophages. Gene 74 protein is an uncharacterised protein of 72 amino acids (8.5 kDa) found in Mycobacterium phage L5.
[]
[]
[]
0
[ "PFAM" ]
[ "PF26893" ]
[ "Phage_L5_Gp74" ]
[ 18 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Caudoviricetes" ]
[ 18 ]
1
[]
[]
0
true
Family
Mycobacterium phage L5 gene 74 protein
Mycobacterium phage L5 gene 74 protein
Phage_L5_Gp74
9
IPR059761
59,761
AF_0970 family
AF_0970
Family
17
false
false
This entry represents the AF_0970 family of small membrane proteins found in sulfate-reducing archaea and bacteria. The family is found in Archaeoglobaceae, particularly Archaeoglobus, and various sulfate-reducing bacterial lineages including Desulfobacteraceae, Dethiobacteraceae, and Dethiobacter. The proteins are app...
[]
[]
[]
0
[ "PFAM" ]
[ "PF27382" ]
[ "AF_0970" ]
[ 17 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Archaeoglobaceae", "Bacteria" ]
[ 10, 7 ]
2
[]
[]
0
true
Family
AF_0970 family
AF_0970 family
AF_0970
7
IPR059762
59,762
AF0631-like, C-terminal four-helix domain
AF0631_C
Domain
16
false
false
This entry represents the C-terminal domain of AF0631-like proteins found in archaea and bacteria. This domain is composed of four short α-helical segments. The family is found predominantly in Archaeoglobi, including Archaeoglobus, Geoglobus, and Ferroglobus species, with additional members in Spirochaetota. The speci...
[]
[]
[]
0
[ "PFAM" ]
[ "PF27426" ]
[ "AF0631_C" ]
[ 16 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Archaea" ]
[ 16 ]
1
[]
[]
0
true
Domain
AF0631-like, C-terminal four-helix domain
AF0631-like, C-terminal four-helix domain
AF0631_C
7
IPR059763
59,763
Staphylococcus phage L54a excisionase
Phage_L54a_excisionase
Family
16
false
false
This entry represents the excisionase family found in L54a-like bacteriophages. Excisionase is necessary, together with integrase, for the excision of prophage from the host genome by site-specific recombination at the att site [ ]. The protein is 59 amino acids (7.2 kDa) and functions as a DNA-binding protein involved...
[]
[]
[]
0
[ "PFAM" ]
[ "PF26912" ]
[ "Phage_L54a_excisionase" ]
[ 16 ]
1
[]
[]
[]
0
[]
0
[ "PUB00162230" ]
[ "2526804" ]
[ "Nucleotide sequence and genetic characterization of staphylococcal bacteriophage L54a int and xis genes." ]
[ 1989 ]
1
[]
[]
0
0
null
[ "Bacillales", "Caudoviricetes" ]
[ 6, 10 ]
2
[]
[]
0
true
Family
Staphylococcus phage L54a excisionase
Staphylococcus phage L54a excisionase
Phage_L54a_excisionase
3
IPR059764
59,764
SPbeta prophage YomF protein, C-terminal domain
YomF_C
Domain
15
false
false
This entry represents the C-terminal domain of YomF. The function of this domain remains unknown. YomF is an uncharacterised protein encoded by the SPbeta prophage in Bacillus subtilis. This protein contains an N-terminal domain , middle domain and a C-terminal domain .
[]
[]
[]
0
[ "PFAM" ]
[ "PF27069" ]
[ "YomF_C" ]
[ 15 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacillus", "Bacillus phage SPbeta" ]
[ 14, 1 ]
2
[]
[]
0
true
Domain
SPbeta prophage YomF protein, C-terminal domain
SPbeta prophage YomF protein, C-terminal domain
YomF_C
9
IPR059766
59,766
SPbeta prophage protein YorO
Phage_YorO
Domain
10
false
false
This entry represents a family of small uncharacterised proteins derived from the SPbeta prophage. The prototype member YorO from Bacillus subtilis strain 168 is a 65 amino acid protein of unknown function. SPbeta is a temperate bacteriophage that integrates into the B. subtilis chromosome, and this protein is encoded ...
[]
[]
[]
0
[ "PFAM" ]
[ "PF27084" ]
[ "Phage_YorO" ]
[ 10 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacillus", "Bacillus phage SPbeta" ]
[ 9, 1 ]
2
[]
[]
0
true
Domain
SPbeta prophage protein YorO
SPbeta prophage protein YorO
Phage_YorO
8
IPR059767
59,767
ShkE, N-terminal domain
ShkE_N
Domain
8
false
false
This entry represents the N-terminal domain in ShkE and related proteins mainly from Dictyostelium discoideum. ShkE is involved in essential cellular processes such as chemotaxis and phagocytosis. It plays a critical role in the regulation of F-actin levels within chemotaxing cells, ensuring proper spatiotemporal contr...
[]
[]
[]
0
[ "PFAM" ]
[ "PF26756" ]
[ "ShkE_N" ]
[ 8 ]
1
[]
[]
[]
0
[]
0
[ "PUB00084837", "PUB00085924" ]
[ "19926274", "10398925" ]
[ "SH2 domains: modulators of nonreceptor tyrosine kinase activity.", "SH2 domains: from structure to energetics, a dual approach to the study of structure-function relationships." ]
[ 2009, 1999 ]
2
[]
[]
0
0
null
[ "Eukaryota" ]
[ 8 ]
1
[]
[]
0
true
Domain
ShkE, N-terminal domain
ShkE, N-terminal domain
ShkE_N
5
IPR059768
59,768
Uncharacterized killer plasmid pGKl-2 protein 1, N-terminal domain
YKP1_N
Domain
7
false
false
This entry represents the N-terminal domain of YKP1, an uncharacterised protein encoded by the killer plasmid pGKL2 from Kluyveromyces lactis. The presence of plasmids pGKL1 and pGKL2 confers the killer phenotype to the host cell by promoting secretion of a toxin that inhibits growth of sensitive strains [ ]. This prot...
[]
[]
[]
0
[ "PFAM" ]
[ "PF28450" ]
[ "YKP1_N" ]
[ 7 ]
1
[]
[]
[]
0
[]
0
[ "PUB00045923" ]
[ "3041369" ]
[ "Genome organization of the killer plasmid pGK12 from Kluyveromyces lactis." ]
[ 1988 ]
1
[]
[]
0
0
null
[ "Saccharomycetaceae" ]
[ 7 ]
1
[]
[]
0
true
Domain
Uncharacterized killer plasmid pGKl-2 protein 1, N-terminal domain
Uncharacterized killer plasmid pGKl-2 protein 1, N-terminal domain
YKP1_N
4
IPR059769
59,769
Meiotically up-regulated gene 10 protein, PH domain
PH_MUG10
Domain
5
false
false
This entry represents a C-terminal PH-like domain found at the C terminus of the MUG10 protein. The Meiotically up-regulated gene 10 protein family is involved in the process of meiosis. Proteins in this family play a role in the complex series of events that lead to the formation of gametes, ensuring the proper segreg...
[]
[]
[]
0
[ "PFAM" ]
[ "PF26663" ]
[ "PH_MUG10" ]
[ 5 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Schizosaccharomyces" ]
[ 5 ]
1
[ "Schizosaccharomyces pombe (strain 972 / ATCC 24843)" ]
[ 1 ]
1
true
Domain
Meiotically up-regulated gene 10 protein, PH domain
Meiotically up-regulated gene 10 protein, PH domain
PH_MUG10
7
IPR059770
59,770
Phage SPO1 gene 47 protein
Phage_SPO1_gp47
Family
5
false
false
This entry represents gene 47 protein found in bacteriophages. The prototype is from Bacillus phage SPO1, a 94 amino acid protein with a molecular weight of 10.5 kDa. The protein is located in the host-takeover module within the terminal redundancy region of the phage genome, suggesting a role in the early stages of in...
[]
[]
[]
0
[ "PFAM" ]
[ "PF26855" ]
[ "Phage_SPO1_gp47" ]
[ 5 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Okubovirus" ]
[ 5 ]
1
[]
[]
0
true
Family
Phage SPO1 gene 47 protein
Phage SPO1 gene 47 protein
Phage_SPO1_gp47
5
IPR059771
59,771
Bacteriophage APSE-1 protein p4
Phage_APSE1_p4
Family
4
false
false
This entry represents protein p4 found in APSE-1-like bacteriophages. Protein p4 is an uncharacterised protein of 73 amino acids (9.0 kDa) found in bacteriophage APSE-1 that infects the secondary endosymbiont of Acyrthosiphon pisum.
[]
[]
[]
0
[ "PFAM" ]
[ "PF26913" ]
[ "Phage_APSE1_p4" ]
[ 4 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Candidatus Williamhamiltonella defendens", "Sendosyvirus" ]
[ 2, 2 ]
2
[]
[]
0
true
Family
Bacteriophage APSE-1 protein p4
Bacteriophage APSE-1 protein p4
Phage_APSE1_p4
7
IPR059772
59,772
Phage Cp-1 terminal protein
Phage_Cp-1_Terminal
Family
3
false
false
The Terminal protein family is crucial for DNA replication, as it is linked to the 5'-ends of both strands of the genome through a phosphodiester bond. This bond is formed between the beta-hydroxyl group of a threonine residue and the 5'-phosphate of the terminal deoxyadenylate [ ]. The family plays a significant role ...
[]
[]
[]
0
[ "PFAM" ]
[ "PF26850" ]
[ "Phage_Cp-1_Terminal" ]
[ 3 ]
1
[]
[]
[]
0
[]
0
[ "PUB00162227", "PUB00162228" ]
[ "3081736", "8757800" ]
[ "Formation of a covalent complex between the terminal protein of pneumococcal bacteriophage Cp-1 and 5'-dAMP.", "In vitro protein-primed initiation of pneumococcal phage Cp-1 DNA replication occurs at the third 3' nucleotide of the linear template: a stepwise sliding-back mechanism." ]
[ 1986, 1996 ]
2
[]
[]
0
0
null
[ "Cepunavirus" ]
[ 3 ]
1
[]
[]
0
true
Family
Phage Cp-1 terminal protein
Phage Cp-1 terminal protein
Phage_Cp-1_Terminal
1
IPR059773
59,773
Phage decoration protein
Phage_decoration
Family
2
false
false
The Decoration protein family from Thermus phage p23-45 plays a crucial role in stabilizing the mature viral capsid shell. It achieves this by cooperatively binding to the expanded capsid, which allows for the packaging of large viral DNA [ ]. The proteins in this family form homotrimers and interact with the major cap...
[]
[]
[]
0
[ "PFAM" ]
[ "PF26852" ]
[ "Phage_decoration" ]
[ 2 ]
1
[]
[]
[]
0
[ "6bl5", "6i9e", "6o3h" ]
3
[ "PUB00095684" ]
[ "30737287" ]
[ "Cryo-EM structure and in vitro DNA packaging of a thermophilic virus with supersized T=7 capsids." ]
[ 2019 ]
1
[]
[]
0
0
null
[ "Oshimavirus" ]
[ 2 ]
1
[]
[]
0
true
Family
Phage decoration protein
Phage decoration protein
Phage_decoration
8