LiteFold/InterPro · Datasets at Hugging Face

IPR059774

59,774

Disruptin gp28

Phage_disruptin

Family

2

false

This entry represents the disruptin family, a class of phage lysis proteins required for outer membrane disruption during bacteriophage lysis of Gram-negative bacterial hosts [ ]. Disruptins are small cationic antimicrobial peptides that function as an alternative to spanins for outer membrane disruption. The prototype...

[]

0

[ "PFAM" ]

[ "PF26810" ]

[ "Phage_disruptin" ]

[ 2 ]

1

[]

0

[]

0

[ "PUB00162229" ]

[ "34339297" ]

[ "Phage-encoded cationic antimicrobial peptide required for lysis." ]

[ 2021 ]

1

[]

0

null

[ "Ermolevavirus" ]

[ 2 ]

1

[]

0

true

Family

Disruptin gp28

Phage_disruptin

5

IPR059775

59,775

Spike protein P1, first jelly-roll domain

Spike_JR1

Domain

1

false

This entry represents the first jelly-roll domain of Spike protein P1 from Pseudoalteromonas phage PM2 [ ]. The Spike protein P1, also known as Protein I, is a key component of the Pseudoalteromonas phage PM2 (Bacteriophage PM2). This protein is responsible for receptor binding and is located at the fivefold vertices o...

[]

0

[ "PFAM" ]

[ "PF22464" ]

[ "Spike_JR1" ]

[ 1 ]

1

[]

0

[ "2w0c" ]

1

[ "PUB00049918" ]

[ "18775333" ]

[ "Insights into virus evolution and membrane biogenesis from the structure of the marine lipid-containing bacteriophage PM2." ]

[ 2008 ]

1

[]

0

null

[ "Pseudoalteromonas phage PM2" ]

[ 1 ]

1

[]

0

true

Domain

Spike protein P1, first jelly-roll domain

Spike_JR1

5

IPR059776

59,776

YibY

Family

1

false

This protein family includes Protein YibY from Escherichia coli, a 36-residues micropeptide encoded by a small open reading frame (smORF) that is found antisense to waaL. Proteins 50 or fewer residues-long have been shown to regulate the functions of larger proteins in a variety of organisms [ ].

[]

0

[ "PFAM" ]

[ "PF23515" ]

[ "YibY" ]

[ 1 ]

1

[]

0

[]

0

[ "PUB00105763" ]

[ "30837344" ]

[ "Identifying Small Proteins by Ribosome Profiling with Stalled Initiation Complexes." ]

[ 2019 ]

1

[]

0

null

[ "Escherichia coli (strain K12)" ]

[ 1 ]

1

[ "Escherichia coli (strain K12)" ]

[ 1 ]

1

true

Family

YibY

3

IPR059777

59,777

Telomerase reverse transcriptase, CTE domain

CTE_TERT

Domain

1

false

This is the CTE (C-terminal element) domain of Telomerase reverse transcriptase from Tetrahymena thermophila (TERT), the catalytic component of the telomerase. This domain adopts a predominantly α-helical structure.

[]

0

[ "PFAM" ]

[ "PF23119" ]

[ "CTE_TERT" ]

[ 1 ]

1

[]

0

[ "6d6v", "7lma", "7lmb", "7uy5", "7uy6", "8gap" ]

6

[ "PUB00153332" ]

[ "29775593" ]

[ "Structure of Telomerase with Telomeric DNA." ]

[ 2018 ]

1

[]

0

null

[ "Tetrahymena thermophila (strain SB210)" ]

[ 1 ]

1

[]

0

true

Domain

Telomerase reverse transcriptase, CTE domain

CTE_TERT

8

IPR059782

59,782

Transmembrane-like, N-terminal domain

TM-like_N

Domain

731

false

This entry represents the N-terminal domain in putative transmembrane proteins and other uncharacterised proteins mostly found in Pseudomonadati. This domain is predicted to fold into a single transmembrane helix.

[]

0

[ "PFAM" ]

[ "PF26978" ]

[ "TM-like_N" ]

[ 731 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Pseudomonadota", "Tanacetum cinerariifolium", "ecological metagenomes" ]

[ 725, 1, 5 ]

3

[]

0

true

Domain

Transmembrane-like, N-terminal domain

TM-like_N

9

IPR059783

59,783

Restriction endonuclease-like, C-terminal domain

Endonuc-like_C

Domain

504

false

This entry represents the C-terminal in a group of uncharacterised bacterial proteins. This domain is predicted to adopt a structure with similarity to restriction endonucleases.

[]

0

[ "PFAM" ]

[ "PF27227" ]

[ "Endonuc-like_C" ]

[ 504 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Piedraia hortae CBS 480.64", "ecological metagenomes", "plasmids" ]

[ 498, 1, 3, 2 ]

4

[]

0

true

Domain

Restriction endonuclease-like, C-terminal domain

Endonuc-like_C

3

IPR059786

59,786

Halobacterial tyrosine recombinase, N-terminal domain

Tyr_recomb_halo_N

Domain

288

false

This entry represents an α-helical domain found at the N-terminal of a family tyrosine recombinase protein from Halobacteria.

[]

0

[ "PFAM" ]

[ "PF26683" ]

[ "Tyr_recomb_halo_N" ]

[ 288 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Halobacteriales" ]

[ 288 ]

1

[]

0

true

Domain

Halobacterial tyrosine recombinase, N-terminal domain

Tyr_recomb_halo_N

5

IPR059787

59,787

CbaC protein

CbaC

Family

196

false

This entry represents a small family of Halobacterial proteins that are annotated as CbaC proteins. The origin of this annotation is uncertain. These proteins are composed of two transmembrane helices. STRING networks of members of this family show it is found associated with COX1 and COX2 proteins suggesting it may ac...

[]

0

[ "PFAM" ]

[ "PF26680" ]

[ "CbaC" ]

[ 196 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Halobacteriales" ]

[ 196 ]

1

[]

0

true

Family

CbaC protein

CbaC

3

IPR059789

59,789

Deconstructed propeller

DPROP

Domain

165

false

This entry represents a conserved region found in uncharacterised proteins from Apicomplexa lineage. It is predicted to fold into a complex structure that in some parts is reminiscent of propeller blades some of which are packed on each other but this does not result in a toroid structure.

[]

0

[ "PFAM" ]

[ "PF27828" ]

[ "DPROP" ]

[ 165 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Apicomplexa" ]

[ 165 ]

1

[]

0

true

Domain

Deconstructed propeller

DPROP

4

IPR059791

59,791

Probable glycosyl hydrolase, C-terminal domain

GH_C

Domain

134

false

This entry represents a domain found in probable glycosyl hydrolases from uncharacterised bacterial proteins. It is predicted to fold into a typical β-sandwich.

[]

0

[ "PFAM" ]

[ "PF28585" ]

[ "GH_C" ]

[ 134 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "metagenomes" ]

[ 126, 8 ]

2

[]

0

true

Domain

Probable glycosyl hydrolase, C-terminal domain

GH_C

3

IPR059792

59,792

Bacteriophage P1 gene 16 protein

Phage_P1_Gp16

Family

124

false

This entry represents gene 16 protein found in P1-like bacteriophages. Gene 16 protein is an uncharacterised protein of 166 amino acids (18.1 kDa) encoded within the tail fiber operon of bacteriophage P1.

[]

0

[ "PFAM" ]

[ "PF26903" ]

[ "Phage_P1_Gp16" ]

[ 124 ]

1

[]

0

[ "9ay5", "9vzk" ]

2

[]

0

[]

0

null

[ "Caudoviricetes", "Gammaproteobacteria", "feces metagenome" ]

[ 10, 113, 1 ]

3

[]

0

true

Family

Bacteriophage P1 gene 16 protein

Phage_P1_Gp16

1

IPR059794

59,794

YRGH domain

YRGH

Domain

66

false

This small domain is found in uncharacterised proteins mainly from fungi. It is named after a highly conserved YRGH sequence motif.

[]

0

[ "PFAM" ]

[ "PF26653" ]

[ "YRGH" ]

[ 66 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Dothideomycetes" ]

[ 66 ]

1

[]

0

true

Domain

YRGH domain

YRGH

4

IPR059795

59,795

WWFGPP domain

WWFGPP

Domain

32

false

This domain is found in uncharacterised proteins mainly from Bacillales. It contains a highly conserved WWFGPP sequence motif after which it was named. It is predicted to adopt an unique α/β structure consisting of a small four-stranded β-sheet and α-helices packed on one side of it.

[]

0

[ "PFAM" ]

[ "PF26920" ]

[ "WWFGPP" ]

[ 32 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Alicyclobacillaceae" ]

[ 32 ]

1

[]

0

true

Domain

WWFGPP domain

WWFGPP

5

IPR059796

59,796

Lockin family

Lockin

Family

23

false

This entry represents Lockin family of proteins that inhibit type I and II Thoeris proteins. These proteins fold into a simple four-stranded meander β-sheet and form propeller-like homohexameric assembly.

[]

0

[ "PFAM" ]

[ "PF26760" ]

[ "Lockin" ]

[ 23 ]

1

[]

0

[ "9p8l" ]

1

[]

0

[]

0

null

[ "Bacteria", "metagenomes" ]

[ 14, 9 ]

2

[]

0

true

Family

Lockin family

Lockin

7

IPR059797

59,797

Type I Thoeris inhibitor Tad5

Tad5

Domain

14

false

This entry represents the Tad5 family of phage proteins that inhibit the bacterial Type I Thoeris defense system. Tad5 binds to ThsB and interacts with its catalytic residue E85, though it does not completely block the active site pocket.

[]

0

[ "PFAM" ]

[ "PF25190" ]

[ "Tad5" ]

[ 14 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Caudoviricetes", "metagenomes" ]

[ 2, 9, 3 ]

3

[]

0

true

Domain

Type I Thoeris inhibitor Tad5

Tad5

6

IPR059799

59,799

Endonuclease/exonuclease/phosphatase family, Ig-like domain

EEP_ig-like

Domain

6

false

This entry corresponds to the C-terminal immunoglobulin-like domain of a putative endonuclease/exonuclease/phosphatase from Beutenbergia cavernae (PDB:4ruw).

[]

0

[ "PFAM" ]

[ "PF22447" ]

[ "EEP_ig-like" ]

[ 6 ]

1

[]

0

[ "4ruw" ]

1

[]

0

[]

0

null

[ "Actinomycetes" ]

[ 6 ]

1

[]

0

true

Domain

Endonuclease/exonuclease/phosphatase family, Ig-like domain

EEP_ig-like

1

IPR059800

59,800

G39P, C-terminal domain

G39P_C

Domain

5

false

G39P inhibits the initiation of DNA replication by blocking G40P replicative helicase. G39P has a bipartite stricture consisting of a folded N-terminal domain and an unfolded C-terminal domain (this entry). The C-terminal is essential for helicase interaction [ ].

[]

0

[ "PFAM" ]

[ "PF27049" ]

[ "G39P_C" ]

[ 5 ]

1

[]

0

[ "1no1" ]

1

[ "PUB00029156" ]

[ "12588876" ]

[ "Structural analysis of Bacillus subtilis SPP1 phage helicase loader protein G39P." ]

[ 2003 ]

1

[]

0

null

[ "Polsinellivirinae" ]

[ 5 ]

1

[]

0

true

Domain

G39P, C-terminal domain

G39P_C

4

IPR059801

59,801

Apicomplexa microprotein

Microp_apicomplexa_22

Family

1

false

This protein family includes uncharacterised microproteins encoded by small open reading frames (smORFs) from apicomplexa, including from the parasite Babesia bovis [ ].

[]

0

[ "PFAM" ]

[ "PF23537" ]

[ "Microp_apicomplexa_22" ]

[ 1 ]

1

[]

0

[]

0

[ "PUB00155743" ]

[ "33294524" ]

[ "Transcriptome dataset of Babesia bovis life stages within vertebrate and invertebrate hosts." ]

[ 2020 ]

1

[]

0

null

[ "Babesia bovis" ]

[ 1 ]

1

[]

0

true

Family

Apicomplexa microprotein

Microp_apicomplexa_22

4

IPR059802

59,802

Nudivirus polyhedrin

NV_polyhedrin

Family

1

false

This entry represents the Nudivirus polyhedrin. Its structure consists mainly of array of helices [ ].

[]

0

[ "PFAM" ]

[ "PF24177" ]

[ "NV_polyhedrin" ]

[ 1 ]

1

[]

0

[ "8bbt", "8bc5", "8bck", "8bcl" ]

4

[ "PUB00155769" ]

[ "37443157" ]

[ "Atomic structure of a nudivirus occlusion body protein determined from a 70-year-old crystal sample." ]

[ 2023 ]

1

[]

0

null

[ "Tipula oleracea nudivirus" ]

[ 1 ]

1

[]

0

true

Family

Nudivirus polyhedrin

NV_polyhedrin

1

IPR059804

59,804

Rv1322/Mb1356/MT1363.1-like

Rv1322/Mb1356/MT1363.1

Domain

3,770

false

This entry represents a domain found in uncharacterised proteins exclusively in Mycobacterium tuberculosis complex species, including M. tuberculosis and M. bovis. The domain comprises the entire length of these 98 amino acid proteins, which are designated as Rv1322 in M. tuberculosis H37Rv and Mb1356 in M. bovis. The ...

[]

0

[ "PFAM" ]

[ "PF27609" ]

[ "Rv1322" ]

[ 3770 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "ecological metagenomes" ]

[ 3650, 120 ]

2

[]

0

true

Domain

Rv1322/Mb1356/MT1363.1-like

Rv1322/Mb1356/MT1363.1

9

IPR059805

59,805

Rv1486c-like protein, C-terminal domain

Rv1486c_C

Domain

3,217

false

This entry represents the C-terminal domain (approximately residues 168-288) of uncharacterised proteins found in mycobacteria. Members of this family include Rv1486c from Mycobacterium tuberculosis, Mb1522c from M. bovis, ML1804 from M. leprae, and MAV321 from M. avium. This domain forms the second part of a two-domai...

[]

0

[ "PFAM" ]

[ "PF27076" ]

[ "Rv1486c_C" ]

[ 3217 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacillati", "metagenomes" ]

[ 3193, 24 ]

2

[]

0

true

Domain

Rv1486c-like protein, C-terminal domain

Rv1486c_C

4

IPR059806

59,806

YmdA, beta-sandwich domain

YmdA_beta-sand

Domain

1,785

false

This entry represents a small β-sandwich domain that comprises most of the YmdA protein. YmdA is an uncharacterised protein of approximately 103-106 amino acids found in Escherichia coli and Salmonella. The protein shows similarity to the N-terminal region of FimA/PapA family fimbrial proteins. YmdA is encoded as part ...

[]

0

[ "PFAM" ]

[ "PF27184" ]

[ "YmdA" ]

[ 1785 ]

1

[]

0

[]

0

[ "PUB00112687", "PUB00162420" ]

[ "17010156", "28633454" ]

[ "Cyclic-di-GMP-mediated signalling within the sigma network of Escherichia coli.", "Long-Term Efficacy of Ultrasound-Guided Injection of IncobotulinumtoxinA in Piriformis Syndrome." ]

[ 2006, 2018 ]

2

[]

0

null

[ "Bacteria", "Klebsiella phage N1M2", "human gut metagenome" ]

[ 1783, 1, 1 ]

3

[ "Escherichia coli (strain K12)" ]

[ 1 ]

1

true

Domain

YmdA, beta-sandwich domain

YmdA_beta-sand

2

IPR059807

59,807

DUF6701, fourth domain

DUF6701_4th

Domain

1,407

false

This entry represents an uncharacterised domain found in a wide range of bacterial cell surface proteins. It is predicted to adopt a β-sandwich with Ig-like topology.

[]

0

[ "PFAM" ]

[ "PF28238" ]

[ "DUF6701_4th" ]

[ 1407 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Heterosigma akashiwo", "ecological metagenomes" ]

[ 1387, 1, 19 ]

3

[]

0

true

Domain

DUF6701, fourth domain

DUF6701_4th

8

IPR059808

59,808

PA0049, N-terminal domain

PA0049_N

Domain

1,310

false

This entry represents the N-terminal domain of the uncharacterised protein PA0049 from Pseudomonas aeruginosa and related bacteria. The full-length PA0049 protein is approximately 550 amino acids long and contains a signal peptide, indicating it is likely secreted or membrane-associated. The protein contains this N-ter...

[]

0

[ "PFAM" ]

[ "PF27118" ]

[ "PA0049_N" ]

[ 1310 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Metarhizium", "marine sediment metagenome" ]

[ 1301, 7, 2 ]

3

[]

0

true

Domain

PA0049, N-terminal domain

PA0049_N

1

IPR059809

59,809

Salmonella phage P22 protein Y8K6

Phage_P22_Y8K6

Family

1,263

false

This entry represents protein Y8K6 found in P22-like bacteriophages. Y8K6 is an uncharacterised protein of 78 amino acids (8.6 kDa) found in the ral-gp17 intergenic region of Salmonella phage P22.

[]

0

[ "PFAM" ]

[ "PF27050" ]

[ "Phage_P22_Y8K6" ]

[ 1263 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Caudoviricetes", "Eukaryota", "metagenomes" ]

[ 886, 153, 2, 222 ]

4

[]

0

true

Family

Salmonella phage P22 protein Y8K6

Phage_P22_Y8K6

6

IPR059810

59,810

Cyclic-di-GMP receptor FimW, N-terminal domain

FimW_N

Domain

2,245

false

This entry represents the N-terminal domain of FimW, a cyclic-di- GMP receptor protein from Pseudomonas aeruginosa, and related proteobacteria. The full-length protein is 607 amino acids and contains this N-terminal domain followed by a PilZ-like domain that binds c-di-GMP and a C-terminal β-barrel domain ( ). FimW is ...

[]

0

[ "PFAM" ]

[ "PF27104" ]

[ "FimW_N" ]

[ 2245 ]

1

[]

0

[]

0

[ "PUB00161961" ]

[ "30581112" ]

[ "A Surface-Induced Asymmetric Program Promotes Tissue Colonization by Pseudomonas aeruginosa." ]

[ 2019 ]

1

[]

0

null

[ "Eukaryota", "Pseudomonadota", "ecological metagenomes" ]

[ 2, 2180, 63 ]

3

[]

0

true

Domain

Cyclic-di-GMP receptor FimW, N-terminal domain

FimW_N

1

IPR059811

59,811

Inner membrane assembly complex subunit 17, C-terminal domain

INA17_C

Domain

1,140

false

This entry represents the C-terminal domain of fungal INA17 proteins. INA17 (Inner membrane assembly complex subunit 17) is a component of the inner membrane assembly complex that promotes the biogenesis of mitochondrial F1F0-ATP synthase [ ]. The protein facilitates assembly of the peripheral stalk and promotes assemb...

[]

0

[ "PFAM" ]

[ "PF28274" ]

[ "INA17_C" ]

[ 1140 ]

1

[]

0

[]

0

[ "PUB00162101" ]

[ "24942160" ]

[ "The INA complex facilitates assembly of the peripheral stalk of the mitochondrial F1Fo-ATP synthase." ]

[ 2014 ]

1

[]

0

null

[ "Fungi" ]

[ 1140 ]

1

[ "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Saccharomyces cerevisiae (strain ATCC 204508 / S288c)", "Schizosaccharomyces pombe (strain 972 / ATCC 24843)" ]

[ 1, 1, 1 ]

3

true

Domain

Inner membrane assembly complex subunit 17, C-terminal domain

INA17_C

5

IPR059812

59,812

Rv1486c-like protein, N-terminal domain

Rv1486c_N

Domain

3,203

false

This entry represents the N-terminal domain of uncharacterised proteins found in mycobacteria. Members of this entry include Rv1486c from Mycobacterium tuberculosis, Mb1522c from M. bovis, ML1804 from M. leprae, and MAV321 from M. avium. The full-length proteins are approximately 288-298 amino acids and appear to have ...

[]

0

[ "PFAM" ]

[ "PF27075" ]

[ "Rv1486c_N" ]

[ 3203 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Actinomycetes", "metagenomes" ]

[ 3190, 13 ]

2

[]

0

true

Domain

Rv1486c-like protein, N-terminal domain

Rv1486c_N

4

IPR059813

59,813

Rv0959-like, third domain

Rv0959_3rd

Domain

3,993

false

This entry represents the third domain found in Rv0959 and related uncharacterised proteins from Mycobacterium tuberculosis complex species. The domain is found in proteins of approximately 672 amino acids that also contain a von Willebrand factor type A (VWA) domain. The proteins containing this domain are found in My...

[]

0

[ "PFAM" ]

[ "PF27098" ]

[ "Rv0959_3rd" ]

[ 3993 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Archaea", "Bacteria", "Metazoa", "unclassified sequences" ]

[ 11, 3887, 2, 93 ]

4

[]

0

true

Domain

Rv0959-like, third domain

Rv0959_3rd

8

IPR059816

59,816

Rv1265-like, N-terminal domain

Rv1265_N

Domain

1,669

false

This entry represents the N-terminal domain of uncharacterised proteins from actinomycetes, including Rv1265 from M. tuberculosis, MT1303 from M. tuberculosis CDC 1551, and Mb1296 from M. bovis. The Rv1265 protein from M. tuberculosis H37Rv has been detected by mass spectrometry, confirming its expression. Subcellular ...

[]

0

[ "PFAM" ]

[ "PF27105" ]

[ "Rv1265_N" ]

[ 1669 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "unclassified sequences" ]

[ 1663, 6 ]

2

[]

0

true

Domain

Rv1265-like, N-terminal domain

Rv1265_N

8

IPR059817

59,817

YubE

Family

840

false

This entry represents YubE proteins found in Escherichia coli and related bacteria. YubE is a small protein of approximately 73 amino acids encoded on the F plasmid. The protein contains a predicted helical structure. YubE is an uncharacterised protein and its function remains to be determined.

[]

0

[ "PFAM" ]

[ "PF27407" ]

[ "YubE" ]

[ 840 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Aphis craccivora", "Bacteria", "Caudoviricetes" ]

[ 1, 836, 3 ]

3

[ "Escherichia coli (strain K12)" ]

[ 1 ]

1

true

Family

YubE

5

IPR059818

59,818

YxiS

Family

715

false

This entry represents YxiS proteins found in Bacillales. YxiS is an uncharacterised protein from Bacillus subtilis strain 168. The function of this protein remains to be determined.

[]

0

[ "PFAM" ]

[ "PF27554" ]

[ "YxiS" ]

[ 715 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacillota", "Phytophthora kernoviae 00238/432" ]

[ 714, 1 ]

2

[]

0

true

Family

YxiS

8

IPR059819

59,819

DUF6701, third domain

DUF6701_3rd

Domain

1,388

false

This entry represents an uncharacterised domain found in a wide range of bacterial cell surface proteins. It is predicted to adopt a β-sandwich with Ig-like topology.

[]

0

[ "PFAM" ]

[ "PF28247" ]

[ "DUF6701_3rd" ]

[ 1388 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Eukaryota", "ecological metagenomes" ]

[ 1362, 4, 22 ]

3

[]

0

true

Domain

DUF6701, third domain

DUF6701_3rd

3

IPR059820

59,820

Probable Calcineurin-like phosphoesterase, transmembrane domain

4TM_phosphoesterase

Domain

2,664

false

This domain is found at the N-terminal of uncharacterised bacterial proteins that contain Calcineurin-like phosphoesterase domain. This domain is predicted to contain four transmembrane helices.

[]

0

[ "PFAM" ]

[ "PF28548" ]

[ "4TM_phosphoesterase" ]

[ 2664 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Russula earlei", "metagenomes" ]

[ 2652, 2, 10 ]

3

[]

0

true

Domain

Probable Calcineurin-like phosphoesterase, transmembrane domain

4TM_phosphoesterase

3

IPR059821

59,821

HI_0983 domain

HI_0983

Domain

651

false

This entry represents the conserved domain of HI_0983 family of uncharacterised proteins found in Haemophilus influenzae. The protein shows structural similarity to Mog1p and belongs to a protein family involved in various cellular processes. The protein is located near the dprA gene, which is required for chromosomal ...

[]

0

[ "PFAM" ]

[ "PF27161" ]

[ "HI_0983" ]

[ 651 ]

1

[]

0

[]

0

[ "PUB00017569" ]

[ "7768823" ]

[ "DNA sequence and characterization of Haemophilus influenzae dprA+, a gene required for chromosomal but not plasmid DNA transformation." ]

[ 1995 ]

1

[]

0

null

[ "Bacteria", "Opisthokonta", "ecological metagenomes" ]

[ 647, 2, 2 ]

3

[]

0

true

Domain

HI_0983 domain

HI_0983

8

IPR059822

59,822

YuaE domain

YuaE

Domain

627

false

This entry represents the YuaE domain found in uncharacterised lipoproteins from Escherichia coli. YuaE is a 137 amino acid protein encoded on the F plasmid (locus ECOK12F014) in Escherichia coli strain K12. The protein contains an N-terminal signal peptide that is processed and a lipid anchor at position 22 (N-palmito...

[]

0

[ "PFAM" ]

[ "PF27278" ]

[ "YuaE" ]

[ 627 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Steinernema glaseri" ]

[ 626, 1 ]

2

[ "Escherichia coli (strain K12)" ]

[ 2 ]

1

true

Domain

YuaE domain

YuaE

3

IPR059823

59,823

YkzU-like domain

YkzU-like

Domain

638

false

This entry represents the conserved domain of YkzU protein, an uncharacterised protein of 172 amino acids found in Bacillus subtilis. YkzU is classified in the COG3409 group and is encoded by the gene ykzU (locus tag BSU14072) on the B. subtilis chromosome. The function of this protein remains to be determined. In some...

[]

0

[ "PFAM" ]

[ "PF27189" ]

[ "YkzU" ]

[ 638 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Methanolapillus", "Opisthokonta", "metagenomes", "phage Lak_Megaphage_RVC_AP3_GC26" ]

[ 606, 3, 25, 3, 1 ]

5

[]

0

true

Domain

YkzU-like domain

YkzU-like

1

IPR059824

59,824

YodN, second domain

YodN_2nd

Domain

616

false

This entry represents the second central domain of the YodN protein found in Bacillus subtilis. This domain adopts an SH3-like barrel fold. YodN is required for efficient spore germination in response to both L-alanine and a mixture of L-asparagine, D-glucose, D-fructose and potassium ions (AGFK) [ ]. The function of t...

[]

0

[ "PFAM" ]

[ "PF27175" ]

[ "YodN_2nd" ]

[ 616 ]

1

[]

0

[]

0

[ "PUB00163275" ]

[ "39530705" ]

[ "Identification and characterization of the Bacillus subtilis spore germination protein GerY." ]

[ 2024 ]

1

[]

0

null

[ "Bacillales" ]

[ 616 ]

1

[]

0

true

Domain

YodN, second domain

YodN_2nd

5

IPR059826

59,826

DUF1699, N-terminal domain

DUF1699_N

Domain

570

false

This entry represents a domain found at the N terminus of an archaeal family of proteins called DUF1699.

[]

0

[ "PFAM" ]

[ "PF28505" ]

[ "DUF1699_N" ]

[ 570 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Archaea", "Bacteria candidate phyla", "Dipodomys ordii", "metagenomes" ]

[ 554, 4, 1, 11 ]

4

[]

0

true

Domain

DUF1699, N-terminal domain

DUF1699_N

8

IPR059827

59,827

Slr1353, N-terminal

Slr1353_N

Domain

552

false

This entry represents the N-terminal domain of Slr1353, an uncharacterised protein from the cyanobacterium Synechocystis sp. PCC 6803. This domain adopts a double-stranded RNA-binding domain-like fold, though its specific nucleic acid binding properties and biological function remain to be determined. The function of t...

[]

0

[ "PFAM" ]

[ "PF27148" ]

[ "Slr1353_N" ]

[ 552 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Caudoviricetes", "metagenomes" ]

[ 449, 89, 14 ]

3

[]

0

true

Domain

Slr1353, N-terminal

Slr1353_N

5

IPR059828

59,828

Vacuole membrane protein 1, C-terminal helical domain

VMP1_C

Domain

3,061

false

This entry represents the C-terminal helical domain of vacuole membrane protein 1 (VMP1), also known as transmembrane protein 49 (TMEM49). This domain is found across eukaryotes including plants, animals, and protists. VMP1 is a multi-pass transmembrane protein localised to the endoplasmic reticulum membrane. The full-...

[]

0

[ "PFAM" ]

[ "PF27639" ]

[ "VMP1_C" ]

[ 3061 ]

1

[]

0

[]

0

[ "PUB00162384" ]

[ "18550798" ]

[ "Vacuole membrane protein 1 is an endoplasmic reticulum protein required for organelle biogenesis, protein secretion, and development." ]

[ 2008 ]

1

[]

0

null

[ "Eukaryota" ]

[ 3061 ]

1

[ "Arabidopsis thaliana", "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Homo sapiens", "Mus musculus", "Oryza sativa subsp. japonica", "Rattus norvegicus", "Zea mays" ]

[ 11, 4, 2, 3, 6, 1, 6, 6, 26 ]

9

true

Domain

Vacuole membrane protein 1, C-terminal helical domain

VMP1_C

2

IPR059829

59,829

EspK, C-terminal domain

EspK_C

Domain

502

false

This entry represents the C-terminal domain of EspK, an ESX-1 secretion- associated protein from Mycobacterium tuberculosis. EspK is a 729 amino acid protein (gene Rv3879c) that may act as a chaperone facilitating EspB secretion through interaction with EccCb1 [ ]. The protein is localised to the cytoplasm and interact...

[]

0

[ "PFAM" ]

[ "PF27215" ]

[ "EspK_C" ]

[ 502 ]

1

[]

0

[ "8ako" ]

1

[ "PUB00161944" ]

[ "17676952" ]

[ "A mycobacterium ESX-1-secreted virulence factor with unique requirements for export." ]

[ 2007 ]

1

[]

0

null

[ "Bacillati" ]

[ 502 ]

1

[]

0

true

Domain

EspK, C-terminal domain

EspK_C

4

IPR059830

59,830

ATP-dependent DNA helicase Q-like 1, UBA domain

UBA_RECQL1

Domain

543

false

This ubiquitin-associated (UBA) domain is found at the N-terminal end of ATP-dependent DNA helicase Q-like 1 from Arabidopsis thaliana (RECQL1) and similar proteins. RECQL1 is thought to be a 3'-5' DNA helicase that may play a role in the repair of DNA. UBA domains are often involved in ubiquitin binding.

[]

0

[ "PFAM" ]

[ "PF28551" ]

[ "UBA_RECQL1" ]

[ 543 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Streptophyta" ]

[ 543 ]

1

[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 4, 2, 3 ]

3

true

Domain

ATP-dependent DNA helicase Q-like 1, UBA domain

UBA_RECQL1

1

IPR059831

59,831

Conidiation-specific protein 8

Con-8

Family

994

false

This entry represents a family of conidiation-specific proteins found in fungi, exemplified by con-8 from Neurospora crassa. The protein is 176 amino acids in length and is expressed early during conidial differentiation [ ]. Conidia are dormant spores produced during asexual reproduction in filamentous fungi. The prot...

[]

0

[ "PFAM" ]

[ "PF28480" ]

[ "Con-8" ]

[ 994 ]

1

[]

0

[]

0

[ "PUB00161884" ]

[ "2521382" ]

[ "Genes expressed during conidiation in Neurospora crassa: characterization of con-8." ]

[ 1989 ]

1

[]

0

null

[ "Pezizomycotina" ]

[ 994 ]

1

[ "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)" ]

[ 1 ]

1

true

Family

Conidiation-specific protein 8

Con-8

6

IPR059832

59,832

PA14_33160 family

PA14_33160

Domain

1,391

false

This entry represents a small α-helical domain found in the PA14_33160 family of uncharacterised secreted proteins found in Pseudomonas aeruginosa. The protein contains a predicted signal peptide and is secreted to the extracellular region. The biological function of this protein family remains unknown.

[]

0

[ "PFAM" ]

[ "PF27144" ]

[ "PA14_33160" ]

[ 1391 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Eukaryota", "ecological metagenomes" ]

[ 1384, 2, 5 ]

3

[]

0

true

Domain

PA14_33160 family

PA14_33160

4

IPR059833

59,833

G-protein coupled receptor 149, C-terminal domain

GPR149_C

Domain

638

false

This entry represents the C-terminal domain of G-protein coupled receptor 149 (GPR149), an orphan receptor belonging to the G-protein coupled receptor 1 family. GPR149 is a seven-transmembrane domain protein localised to the cell membrane and acts as a probable neuropeptide receptor. The full-length protein contains an...

[]

0

[ "PFAM" ]

[ "PF28499" ]

[ "GPR149_C" ]

[ 638 ]

1

[]

0

[]

0

[ "PUB00053635", "PUB00161992" ]

[ "12679517", "12065666" ]

[ "The G protein-coupled receptor repertoires of human and mouse.", "A novel seven transmembrane receptor induced during the early steps of astrocyte differentiation identified by differential expression." ]

[ 2003, 2002 ]

2

[]

0

null

[ "Vertebrata" ]

[ 638 ]

1

[ "Homo sapiens", "Mus musculus", "Rattus norvegicus" ]

[ 2, 2, 2 ]

3

true

Domain

G-protein coupled receptor 149, C-terminal domain

GPR149_C

7

IPR059834

59,834

YomQ, N-terminal domain

Phage_YomQ_N

Domain

466

false

This entry represents the N-terminal domain of YomQ, an uncharacterised protein of 116 amino acids from Bacillus subtilis. YomQ is derived from the SPbeta prophage and is encoded by the gene yomQ (locus tag BSU21260) on the B. subtilis chromosome. The function of this protein remains to be determined.

[]

0

[ "PFAM" ]

[ "PF27183" ]

[ "Phage_YomQ_N" ]

[ 466 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Viruses" ]

[ 392, 74 ]

2

[]

0

true

Domain

YomQ, N-terminal domain

Phage_YomQ_N

5

IPR059835

59,835

Rv1352-like, extracellular domain

Rv1352

Domain

1,834

false

This entry represents an extracellular domain found in uncharacterised proteins from the Mycobacterium tuberculosis complex, including Rv1352 from M. tuberculosis, MT1395 from M. tuberculosis CDC 1551, and Mb1387 from M. bovis. These proteins are 123 amino acids in length and contain an N-terminal signal peptide (resid...

[]

0

[ "PFAM" ]

[ "PF27111" ]

[ "Rv1352" ]

[ 1834 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Caudoviricetes", "Methanobrevibacter", "ecological metagenomes" ]

[ 1817, 6, 4, 7 ]

4

[]

0

true

Domain

Rv1352-like, extracellular domain

Rv1352

3

IPR059836

59,836

Sll1247, C-terminal helical domain

Sll1247_C

Domain

455

false

This entry represents the C-terminal helical domain of Sll1247, an uncharacterised protein from the cyanobacterium Synechocystis sp. PCC 6803. The function of this C-terminal helical domain is yet to be determined.

[]

0

[ "PFAM" ]

[ "PF27138" ]

[ "Sll1247_C" ]

[ 455 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Cyanobacteriota" ]

[ 455 ]

1

[]

0

true

Domain

Sll1247, C-terminal helical domain

Sll1247_C

2

IPR059837

59,837

Nucleoporin NUP53, C-terminal domain

NUP53_C

Domain

930

false

This entry represents the C-terminal domain of nucleoporin NUP53, a component of the nuclear pore complex (NPC) found in eukaryotes. NUP53 functions as both a structural component of the NPC and as a docking partner for nuclear transport factors [ ]. The protein is part of a tetrameric module comprising NUP192-NUP170-N...

[]

0

[ "PFAM" ]

[ "PF28376" ]

[ "NUP53_C" ]

[ 930 ]

1

[]

0

[]

0

[ "PUB00155871" ]

[ "21784248" ]

[ "Insight into structure and assembly of the nuclear pore complex by utilizing the genome of a eukaryotic thermophile." ]

[ 2011 ]

1

[]

0

null

[ "Eukaryota" ]

[ 930 ]

1

[ "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)" ]

[ 1 ]

1

true

Domain

Nucleoporin NUP53, C-terminal domain

NUP53_C

6

IPR059838

59,838

Bacteriophage T4 protein rIIB

Phage_T4_rIIB

Family

896

false

This entry represents protein rIIB found in T4-like bacteriophages. Protein rIIB is transcribed prior to replication and forms part of the replication complex. The protein has DNA-binding properties and localises to the host cell inner membrane. The protein is 312 amino acids (35.5 kDa) and is expressed as an early pro...

[]

0

[ "PFAM" ]

[ "PF26926" ]

[ "Phage_T4_rIIB" ]

[ 896 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Eukaryota", "Viruses", "metagenomes" ]

[ 52, 3, 827, 14 ]

4

[]

0

true

Family

Bacteriophage T4 protein rIIB

Phage_T4_rIIB

6

IPR059839

59,839

PGSIP7/8, C-terminal domain

PGSIP7/8_C

Domain

955

false

This entry represents the C-terminal in plant glycogenin-like starch initiation protein 7 (PGSIP7), a member of the glycosyltransferase family 8 (GT8). PGSIP7 is a multi-pass membrane protein with six predicted transmembrane helices. The protein belongs to the glycogenin subfamily and contains manganese binding sites. ...

[]

0

[ "PFAM" ]

[ "PF28460" ]

[ "PGSIP7_C" ]

[ 955 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Viridiplantae" ]

[ 955 ]

1

[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 11, 8, 24 ]

3

true

Domain

PGSIP7/8, C-terminal domain

PGSIP7/8_C

7

IPR059840

59,840

Putative lipoprotein YvcA

YvcA

Family

442

false

This entry represents the putative lipoprotein YvcA that belongs to the Mog1p superfamily. YvcA is required for complex colony architecture [ ]. The protein is upregulated by DegU and Spo0A, and its disruption results in loss of complex colony architecture and fruiting body-like structures [ ]. YvcA is a membrane-ancho...

[]

0

[ "PFAM" ]

[ "PF27181" ]

[ "YvcA_Mog1p" ]

[ 442 ]

1

[]

0

[]

0

[ "PUB00162428" ]

[ "17590234" ]

[ "DegU co-ordinates multicellular behaviour exhibited by Bacillus subtilis." ]

[ 2007 ]

1

[]

0

null

[ "Bacillales" ]

[ 442 ]

1

[]

0

true

Family

Putative lipoprotein YvcA

YvcA

2

IPR059842

59,842

Y4lF, C-terminal domain

TIRY4lF

Domain

419

false

This entry represents the a domain found in the Y4lF protein from Sinorhizobium fredii. The protein is 323 amino acids in length and contains a TIR domain ( ) at the N-terminal [ ]. Y4lF is encoded on the symbiotic plasmid pNGR234a and is found in the rhizobial strain NGR234, which forms nitrogen-fixing symbioses with ...

[]

0

[ "PFAM" ]

[ "PF27176" ]

[ "TIRY4lF" ]

[ 419 ]

1

[]

0

[]

0

[ "PUB00113962" ]

[ "19376903" ]

[ "Rhizobium sp. strain NGR234 possesses a remarkable number of secretion systems." ]

[ 2009 ]

1

[]

0

null

[ "Bacteria", "unclassified sequences" ]

[ 412, 7 ]

2

[]

0

true

Domain

Y4lF, C-terminal domain

TIRY4lF

3

IPR059843

59,843

KilB plasmid transfer protein

KilB

Family

781

false

This entry represents the KilB protein family involved in bacterial plasmid transfer. The prototype member from Streptomyces lividans plasmid pIJ101 is a 147 amino acid protein that functions in conjugative plasmid transfer. The protein contains a hydrophobic N-terminal region (residues 1-20) that likely serves as a me...

[]

0

[ "PFAM" ]

[ "PF27072" ]

[ "KilB" ]

[ 781 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria" ]

[ 781 ]

1

[]

0

true

Family

KilB plasmid transfer protein

KilB

9

IPR059844

59,844

CIP1, helical domain

CIP1_helical

Domain

1,195

false

This entry represents an α-helical domain found in CIP1 proteins. CIP1 is a cyclin-dependent kinase inhibitor that acts on the CDC28/CLN2 complex and negatively regulates the G1/S phase transition [ , ]. The protein is induced by environmental stress and contributes to osmostress-induced transitory G1 delay. CIP1 local...

[]

0

[ "PFAM" ]

[ "PF28255" ]

[ "CIP1_HTH" ]

[ 1195 ]

1

[]

0

[]

0

[ "PUB00161876", "PUB00161877" ]

[ "27005485", "28676626" ]

[ "Identification of YPL014W (Cip1) as a novel negative regulator of cyclin-dependent kinase in Saccharomyces cerevisiae.", "Yeast Cip1 is activated by environmental stress to inhibit Cdk1-G1 cyclins via Mcm1 and Msn2/4." ]

[ 2016, 2017 ]

2

[]

0

null

[ "Eukaryota" ]

[ 1195 ]

1

[ "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Saccharomyces cerevisiae (strain ATCC 204508 / S288c)" ]

[ 1, 1 ]

2

true

Domain

CIP1, helical domain

CIP1_helical

5

IPR059845

59,845

RhiA-like

RhiA

Family

782

false

This entry represents the RhiA protein from Rhizobium leguminosarum and related proteins. RhiA is one of the rhizosphere- expressed genes that can influence nodulation by Rhizobium leguminosarum biovar viciae [ ]. The protein may be involved in plant-microbe interaction, though the specific function remains to be deter...

[]

0

[ "PFAM" ]

[ "PF27136" ]

[ "RhiA_N" ]

[ 782 ]

1

[]

0

[]

0

[ "PUB00014295" ]

[ "1597418" ]

[ "Molecular characterization and regulation of the rhizosphere-expressed genes rhiABCR that can influence nodulation by Rhizobium leguminosarum biovar viciae." ]

[ 1992 ]

1

[]

0

null

[ "Bacteria", "Eukaryota" ]

[ 395, 387 ]

2

[]

0

true

Family

RhiA-like

RhiA

3

IPR059846

59,846

Functional amyloid protein FapB/FapC

FapB/C

Family

2,085

false

This entry represents the FapB/FapC family of functional amyloid proteins found in Pseudomonas species. These proteins are components of the Fap (functional amyloid in Pseudomonas) system that forms extracellular amyloid fibrils. FapC is the major structural component of the amyloid fibrils, while FapB is a minor compo...

[]

0

[ "PFAM" ]

[ "PF27129" ]

[ "FapBC" ]

[ 2085 ]

1

[]

0

[ "9nqd", "9u4u" ]

2

[ "PUB00155432" ]

[ "23504942" ]

[ "Expression of Fap amyloids in Pseudomonas aeruginosa, P. fluorescens, and P. putida results in aggregation and increased biofilm formation." ]

[ 2013 ]

1

[]

0

null

[ "Bacteria", "Knufia peltigerae", "mine drainage metagenome" ]

[ 2072, 2, 11 ]

3

[]

0

true

Family

Functional amyloid protein FapB/FapC

FapB/C

1

IPR059848

59,848

Regulator of G-protein signalling 9-binding protein, C-terminal domain

RGS9BP_C

Domain

621

false

This entry represents the C-terminal domain of regulator of G-protein signalling 9-binding protein (RGS9BP), also known as RGS9-anchoring protein (R9AP). This C-terminal domain contains the transmembrane anchor region that localises the protein to membranes. The domain spans approximately the final 25 amino acids and f...

[]

0

[ "PFAM" ]

[ "PF28461" ]

[ "RGS9BP_C" ]

[ 621 ]

1

[ "REACTOME", "REACTOME", "REACTOME" ]

[ "R-BTA-2514859", "R-HSA-2514859", "R-MMU-2514859" ]

[ "REACTOME:R-BTA-2514859", "REACTOME:R-HSA-2514859", "REACTOME:R-MMU-2514859" ]

3

[]

0

[ "PUB00060534", "PUB00162277" ]

[ "12560335", "12119397" ]

[ "Activation of RGS9-1GTPase acceleration by its membrane anchor, R9AP.", "R9AP, a membrane anchor for the photoreceptor GTPase accelerating protein, RGS9-1." ]

[ 2003, 2002 ]

2

[]

0

null

[ "Vertebrata" ]

[ 621 ]

1

[ "Danio rerio", "Homo sapiens", "Mus musculus", "Rattus norvegicus" ]

[ 1, 1, 1, 2 ]

4

true

Domain

Regulator of G-protein signalling 9-binding protein, C-terminal domain

RGS9BP_C

6

IPR059850

59,850

Bacteriophage T4 protein Y07E

Phage_T4_Y07E

Family

307

false

This entry represents the Y07E protein family found in T4-like bacteriophages. Y07E is an uncharacterised protein found in the repEA-segC intergenic region of bacteriophage T4. The protein contains a predicted disordered region.

[]

0

[ "PFAM" ]

[ "PF26906" ]

[ "Phage_T4_Y07E" ]

[ 307 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Pseudomonadota", "Viruses" ]

[ 21, 286 ]

2

[]

0

true

Family

Bacteriophage T4 protein Y07E

Phage_T4_Y07E

1

IPR059851

59,851

PM0630-like, beta-sandwich domain

PM0630_beta-sand

Domain

308

false

This entry represents a small β-sandwich domain that comprises most of the PM0630 protein. PM0630 is an uncharacterised protein found in Pasteurella multocida. The protein contains a signal peptide suggesting it is secreted. PM0630 is encoded by the gene PM0630 on the P. multocida chromosome. The function of this prote...

[]

0

[ "PFAM" ]

[ "PF27186" ]

[ "PM0630" ]

[ 308 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "ecological metagenomes" ]

[ 304, 4 ]

2

[]

0

true

Domain

PM0630-like, beta-sandwich domain

PM0630_beta-sand

7

IPR059852

59,852

Uncharacterized protein PM1083

PM1083

Family

304

false

This entry represents PM1083, an uncharacterised protein from Pasteurella multocida. PM1083 contains an N-terminal signal peptide and is predicted to be secreted. The protein is found in Gammaproteobacteria and is conserved in Pasteurellaceae. The function of this protein family remains to be determined.

[]

0

[ "PFAM" ]

[ "PF27214" ]

[ "PM1083" ]

[ 304 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "ecological metagenomes" ]

[ 300, 4 ]

2

[]

0

true

Family

Uncharacterized protein PM1083

PM1083

1

IPR059853

59,853

Probable PDZ-protease, C-terminal helical domain

CHD_PDZ-protease

Domain

2,407

false

This domain is found C-terminal in proteins that likely related to PDZ-proteases. It is predicted to fold into array of helices

[]

0

[ "PFAM" ]

[ "PF28547" ]

[ "CHD_PDZ-protease" ]

[ 2407 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Caudoviricetes", "Eukaryota", "metagenomes" ]

[ 2259, 4, 89, 55 ]

4

[]

0

true

Domain

Probable PDZ-protease, C-terminal helical domain

CHD_PDZ-protease

8

IPR059854

59,854

Uncharacterized protein YfdP

YfdP

Domain

1,501

false

This entry represents the YfdP protein family found in Escherichia coli and related enterobacteria. YfdP is a small protein of approximately 120 amino acids with similarity to bacteriophage T4 protein y06Q. The function of this protein family remains to be determined.

[]

0

[ "PFAM" ]

[ "PF27127" ]

[ "YfdP" ]

[ 1501 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Viruses", "metagenomes" ]

[ 1398, 96, 7 ]

3

[ "Escherichia coli (strain K12)" ]

[ 1 ]

1

true

Domain

Uncharacterized protein YfdP

YfdP

3

IPR059855

59,855

AF_1680-like domain

AF_1680_dom

Domain

295

false

This entry represents a domain found standalone in the AF_1680 protein and in uncharacterised proteins found in Archaea. AF_1680 is found in Archaeoglobus fulgidus and related archaeal species. The function of this domain remains to be determined.

[]

0

[ "PFAM" ]

[ "PF27235" ]

[ "AF_1680" ]

[ 295 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Methanobacteriota", "metagenomes" ]

[ 283, 6, 6 ]

3

[]

0

true

Domain

AF_1680-like domain

AF_1680_dom

3

IPR059856

59,856

Uncharacterized protein 2 in cox locus

YCO2

Family

1,976

false

This entry represents the uncharacterised protein 2 in the Cox locus (YCO2).

[]

0

[ "PFAM" ]

[ "PF27516" ]

[ "YCO2" ]

[ 1976 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Eukaryota", "ecological metagenomes" ]

[ 1956, 2, 18 ]

3

[]

0

true

Family

Uncharacterized protein 2 in cox locus

YCO2

2

IPR059857

59,857

Pneumocandin biosynthesis cluster protein B, C-terminal domain

GloB_C

Domain

934

false

This entry represents the C-terminal domain in Pneumocandin biosynthesis cluster protein B and related proteins such as Echinocandin B biosynthetic cluster protein J and Hypothemycin biosynthesis cluster protein hpm4. GloB is part of gene cluster that mediates the biosynthesis of pneumocandins, lipohexapeptides of the ...

[]

0

[ "PFAM" ]

[ "PF28402" ]

[ "GloB_C" ]

[ 934 ]

1

[]

0

[]

0

[ "PUB00161982", "PUB00161983" ]

[ "18567690", "20222707" ]

[ "Genes for the biosynthesis of the fungal polyketides hypothemycin from Hypomyces subiculosus and radicicol from Pochonia chlamydosporia.", "Enzymatic synthesis of resorcylic acid lactones by cooperation of fungal iterative polyketide synthases involved in hypothemycin biosynthesis." ]

[ 2008, 2010 ]

2

[]

0

null

[ "Eukaryota" ]

[ 934 ]

1

[]

0

true

Domain

Pneumocandin biosynthesis cluster protein B, C-terminal domain

GloB_C

9

IPR059858

59,858

VspR, N-terminal domain

VspR_N

Domain

542

false

This entry represents the N-terminal domain of VspR, a transcriptional regulator from Vibrio cholerae. VspR is a 187 amino acid transcriptional repressor (gene VC_0177) that represses transcription of several genes encoded within the Vibrio 7th pandemic island-1 (VSP-1), including dncV, VC_0176, VC_0178 and VC_0180 [ ]...

[]

0

[ "PFAM" ]

[ "PF27213" ]

[ "VspR_N" ]

[ 542 ]

1

[]

0

[]

0

[ "PUB00138261" ]

[ "22500802" ]

[ "Coordinated regulation of accessory genetic elements produces cyclic di-nucleotides for V. cholerae virulence." ]

[ 2012 ]

1

[]

0

null

[ "Bacteria", "metagenomes" ]

[ 538, 4 ]

2

[]

0

true

Domain

VspR, N-terminal domain

VspR_N

7

IPR059860

59,860

YopA, C-terminal domain

YopA_C

Domain

259

false

This entry represents the C-terminal domain of YopA, an uncharacterised protein from Bacillus subtilis. YopA is a single-pass membrane protein (gene BSU20960) derived from the SPbeta prophage in Bacillus subtilis strain 168. The protein is predicted to be localised to the cell membrane with a transmembrane helix. This ...

[]

0

[ "PFAM" ]

[ "PF27216" ]

[ "YopA_C" ]

[ 259 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacillus phage SPbeta", "Bacteria", "Methanosarcina", "metagenomes" ]

[ 1, 250, 3, 5 ]

4

[]

0

true

Domain

YopA, C-terminal domain

YopA_C

8

IPR059861

59,861

BZIP transcription factor, 1 C-terminal domain

BZP1_C

Domain

3,253

false

This entry represents the C-terminal domain of bZIP transcription factor 1 (BZP1) found in Oomycota, primarily in Phytophthora species and related organisms. BZP1 is required for normal zoospore movement, formation of appressoria by germinated zoospore cysts, and plant infection in Phytophthora infestans [ ]. The prote...

[]

0

[ "PFAM" ]

[ "PF27643" ]

[ "BZP1_C" ]

[ 3253 ]

1

[]

0

[]

0

[ "PUB00161837" ]

[ "15819621" ]

[ "A bZIP transcription factor from Phytophthora interacts with a protein kinase and is required for zoospore motility and plant infection." ]

[ 2005 ]

1

[]

0

null

[ "Oomycota" ]

[ 3253 ]

1

[]

0

true

Domain

BZIP transcription factor, 1 C-terminal domain

BZP1_C

9

IPR059863

59,863

DEXH1/3/5, N-terminal domain

DEXH1_3_5_N

Domain

2,245

false

This domain is found towards the N-terminal of DExH-box ATP-dependent RNA helicase DExH1/3/5 from Arabidopsis thaliana and related proteins. This domain is predicted to show an α-β configuration.

[]

0

[ "PFAM" ]

[ "PF27261" ]

[ "DEXH1_3_5_N" ]

[ 2245 ]

1

[ "EC" ]

[ "3.6.4.13" ]

[ "EC:3.6.4.13" ]

1

[]

0

[]

0

[]

0

null

[ "Eukaryota" ]

[ 2245 ]

1

[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 20, 9, 27 ]

3

true

Domain

DEXH1/3/5, N-terminal domain

DEXH1_3_5_N

1

IPR059864

59,864

LytA-like, beta-barrel domain

OB_LytA

Domain

505

false

This entry represents a small β-barrel domain belonging to the OB-fold superfamily found in membrane-bound lipoproteins such as LytA and YqiH from Bacillus subtilis. LytA may play a role in the secretion of LytB and LytC autolysins and is subject to repression by LytR [ ]. These proteins are lipid-anchored to the cell ...

[]

0

[ "PFAM" ]

[ "PF27162" ]

[ "OB_LytA" ]

[ 505 ]

1

[]

0

[]

0

[ "PUB00021031" ]

[ "1357079" ]

[ "Sequencing and analysis of the Bacillus subtilis lytRABC divergon: a regulatory unit encompassing the structural genes of the N-acetylmuramoyl-L-alanine amidase and its modifier." ]

[ 1992 ]

1

[]

0

null

[ "Bacillota", "Phytophthora kernoviae 00238/432", "ecological metagenomes" ]

[ 502, 1, 2 ]

3

[]

0

true

Domain

LytA-like, beta-barrel domain

OB_LytA

6

IPR059865

59,865

Acb5 phage protein

Acb5

Family

488

false

This entry represents the Acb5 phage proteins that inhibit the bacterial anti-phage defense system called CBASS. These proteins degrade the CBASS-derived signaling molecules, thus disrupting the immune signaling cascade. They are predicted to fold into a simple structure composed of a curved five-stranded antiparallel ...

[]

0

[ "PFAM" ]

[ "PF26761" ]

[ "Acb5" ]

[ 488 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Halobacteriales", "Viruses", "metagenomes" ]

[ 395, 15, 55, 23 ]

4

[]

0

true

Family

Acb5 phage protein

Acb5

4

IPR059866

59,866

YonG, N-terminal domain

YonG_N

Domain

248

false

This entry represents the N-terminal domain of the YonG protein found in Bacillus subtilis. The full-length YonG protein is 306 amino acids and is derived from the SPbeta prophage. YonG is encoded by the yonG gene (locus tag BSU21100) in Bacillus subtilis strain 168. The specific function of this N-terminal domain rema...

[]

0

[ "PFAM" ]

[ "PF27269" ]

[ "YonG_N" ]

[ 248 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Tritrichomonas musculus", "Viruses", "ecological metagenomes" ]

[ 161, 1, 83, 3 ]

4

[]

0

true

Domain

YonG, N-terminal domain

YonG_N

2

IPR059867

59,867

YagJ-like domain

YagJ_dom

Domain

745

false

This entry represents the YagJ family of proteins found in Escherichia coli. YagJ is encoded by the CP4-6 prophage and appears to be involved in radiation resistance, as disruption of the gene results in 3-fold increased sensitivity to X-radiation [ ]. The protein belongs to the COG1061 functional category. The specifi...

[]

0

[ "PFAM" ]

[ "PF27151" ]

[ "YagJ" ]

[ 745 ]

1

[]

0

[]

0

[ "PUB00162410" ]

[ "27718375" ]

[ "Screen for genes involved in radiation survival of Escherichia coli and construction of a reference database." ]

[ 2016 ]

1

[]

0

null

[ "Archaea", "Bacteria", "Phage sp. ctrsQ3", "metagenomes" ]

[ 8, 727, 1, 9 ]

4

[ "Escherichia coli (strain K12)" ]

[ 1 ]

1

true

Domain

YagJ-like domain

YagJ_dom

6

IPR059869

59,869

Y4lR, C-terminal helical domain

Y4lR_C

Domain

234

false

This entry represents the C-terminal helical domain of Y4lR, an uncharacterised protein from Sinorhizobium fredii. Y4lR is a 522 amino acid protein (gene NGR_a02600) located on the symbiotic plasmid pNGR234a. The protein is annotated as COG3318 in the eggNOG database. This domain is the fourth domain in the multi-domai...

[]

0

[ "PFAM" ]

[ "PF27203" ]

[ "Y4lR_C" ]

[ 234 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "ecological metagenomes" ]

[ 232, 2 ]

2

[]

0

true

Domain

Y4lR, C-terminal helical domain

Y4lR_C

4

IPR059871

59,871

Uncharacterized protein MJ0235

MJ0235

Family

232

false

This entry represents the MJ0235 protein family, an uncharacterised protein found in Archaea. MJ0235 is found in Methanocaldococcus jannaschii and related archaeal species. The function of this small protein family remains to be determined. This entry also includes uncharacterised sequences from bacteria.

[]

0

[ "PFAM" ]

[ "PF27273" ]

[ "MJ0235" ]

[ 232 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Archaea", "Archaeoglobus profundus pleomorphic provirus 1", "Bacteria", "ecological metagenomes" ]

[ 99, 1, 129, 3 ]

4

[]

0

true

Family

Uncharacterized protein MJ0235

MJ0235

2

IPR059872

59,872

Phage T4 Y04K protein

Phage_T4_Y04K

Family

226

false

This entry represents protein y04K found in bacteriophages. The prototype is from bacteriophage T4, a 106 amino acid protein with a molecular weight of 12.6 kDa located in the pin-nrdC intergenic region. The protein is found in the T4 genome region between map positions 48.266 kb and 39.166 kb and remains uncharacteris...

[]

0

[ "PFAM" ]

[ "PF26835" ]

[ "Phage_T4_Y04K" ]

[ 226 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Viruses" ]

[ 20, 206 ]

2

[]

0

true

Family

Phage T4 Y04K protein

Phage_T4_Y04K

8

IPR059874

59,874

YuaX

Domain

227

false

This entry represents uncharacterised protein YuaX from the F plasmid of Escherichia coli and related proteobacteria. The protein is 96 amino acids in length and is encoded by the yuaX gene (also known as yebA). The protein is found across diverse proteobacterial lineages including Gammaproteobacteria, Betaproteobacter...

[]

0

[ "PFAM" ]

[ "PF27363" ]

[ "YuaX" ]

[ 227 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Pseudomonadati", "Tanacetum cinerariifolium", "marine sediment metagenome" ]

[ 224, 1, 2 ]

3

[ "Escherichia coli (strain K12)" ]

[ 1 ]

1

true

Domain

YuaX

8

IPR059875

59,875

VspR, C-terminal haipin domain

VspR_C

Domain

660

false

This entry represents the C-terminal hairpin domain of VspR, a transcriptional regulator from Vibrio cholerae. VspR is a 187 amino acid transcriptional repressor (gene VC_0177) that represses transcription of several genes encoded within the Vibrio 7th pandemic island-1 (VSP-1), including dncV, VC_0176, VC_0178 and VC_...

[]

0

[ "PFAM" ]

[ "PF27192" ]

[ "VspR_C" ]

[ 660 ]

1

[]

0

[]

0

[ "PUB00138261" ]

[ "22500802" ]

[ "Coordinated regulation of accessory genetic elements produces cyclic di-nucleotides for V. cholerae virulence." ]

[ 2012 ]

1

[]

0

null

[ "Bacteria", "Xylariales", "metagenomes" ]

[ 651, 3, 6 ]

3

[]

0

true

Domain

VspR, C-terminal haipin domain

VspR_C

9

IPR059876

59,876

Chloroethene reductive dehalogenase membrane anchor protein

VcrB

Family

438

false

This entry represents VcrB, a probable chloroethene reductive dehalogenase membrane anchor protein from Dehalococcoides mccartyi. VcrB is a 93 amino acid multi-pass transmembrane protein with three predicted transmembrane helices that may act as a membrane anchor for the chloroethene reductive dehalogenase VcrA [ ]. Th...

[]

0

[ "PFAM" ]

[ "PF27193" ]

[ "VcrB" ]

[ 438 ]

1

[]

0

[ "8q4h" ]

1

[ "PUB00154372" ]

[ "15294827" ]

[ "Molecular identification of the catabolic vinyl chloride reductase from Dehalococcoides sp. strain VS and its environmental distribution." ]

[ 2004 ]

1

[]

0

null

[ "Actinidia", "Bacteria", "ecological metagenomes" ]

[ 2, 422, 14 ]

3

[]

0

true

Family

Chloroethene reductive dehalogenase membrane anchor protein

VcrB

3

IPR059878

59,878

MJ1433, N-terminal helical domain

MJ1433_N

Domain

420

false

This entry represents the N-terminal helical domain of the uncharacterized protein MJ1433 from Methanocaldococcus jannaschii and related archaeal species. This protein contains two predicted transmembrane helices. This N-terminal helical domain is distinct from the helical domain at the C-terminal which is predicted to...

[]

0

[ "PFAM" ]

[ "PF27246" ]

[ "MJ1433_N" ]

[ 420 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Kipferlia bialata", "Methanobacteriati", "ecological metagenomes" ]

[ 220, 1, 175, 24 ]

4

[]

0

true

Domain

MJ1433, N-terminal helical domain

MJ1433_N

6

IPR059879

59,879

HI_1241-like

HI_1241

Family

620

false

This entry represents HI_1241, an uncharacterised integral membrane protein from Haemophilus influenzae. HI_1241 is a 266 amino acid multi-pass membrane protein (gene HI_1241) with eight predicted transmembrane helices. The protein is localised to the cell membrane and is found in Gammaproteobacteria. The function of t...

[]

0

[ "PFAM" ]

[ "PF27206" ]

[ "HI_1241" ]

[ 620 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria" ]

[ 620 ]

1

[]

0

true

Family

HI_1241-like

HI_1241

3

IPR059880

59,880

AclK-like, C-terminal domain

AclK_C

Domain

1,071

false

This entry represents the C-terminal helix hairpin found in AclK proteins. AclK is a gamma-glutamyl cyclotransferase involved in the biosynthesis of aspirochlorine, a halogenated mycotoxin with antifungal properties [ ]. The protein catalyses the conversion of alpha-(gamma-L- glutamyl)-L-amino acids to 5-oxo-L-proline ...

[]

0

[ "PFAM" ]

[ "PF28338" ]

[ "AclK_C" ]

[ 1071 ]

1

[ "EC", "METACYC", "METACYC" ]

[ "4.3.2.9", "PWY-4041", "PWY-7533" ]

[ "EC:4.3.2.9", "METACYC:PWY-4041", "METACYC:PWY-7533" ]

3

[]

0

[ "PUB00094238" ]

[ "25302411" ]

[ "Biosynthesis of the halogenated mycotoxin aspirochlorine in koji mold involves a cryptic amino acid conversion." ]

[ 2014 ]

1

[]

0

null

[ "Eukaryota" ]

[ 1071 ]

1

[ "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)" ]

[ 1 ]

1

true

Domain

AclK-like, C-terminal domain

AclK_C

9

IPR059881

59,881

YkzS-like protein

YkzS

Domain

1,366

false

This entry represents a family of small uncharacterised proteins found in Bacillus species. The prototype member YkzS from Bacillus subtilis strain 168 is a 64 amino acid protein of unknown function. This protein family appears to be conserved among Bacillus species but its biological role remains to be determined. The...

[]

0

[ "PFAM" ]

[ "PF27074" ]

[ "YkzS" ]

[ 1366 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "bioreactor metagenome" ]

[ 1365, 1 ]

2

[]

0

true

Domain

YkzS-like protein

YkzS

1

IPR059882

59,882

YoqU

Domain

190

false

This entry represents YoqU proteins derived from SPbeta prophage and related bacteriophages. YoqU is a small protein of approximately 137 amino acids found in the SPbeta prophage of Bacillus subtilis and related systems. YoqU proteins are associated with prophage elements integrated into bacterial genomes. The function...

[]

0

[ "PFAM" ]

[ "PF27459" ]

[ "YoqU" ]

[ 190 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Caudoviricetes" ]

[ 186, 4 ]

2

[]

0

true

Domain

YoqU

2

IPR059883

59,883

IcsB/BopA-like, middle domain

IcsB/BopA_M

Domain

432

false

This entry represents the middle domain of IcsB, BopA and similar sequences. IcsB is a virulence-associated N-epsilon-fatty acyltransferase from Shigella flexneri. The full-length IcsB protein mediates lysine-stearoylation of host Rho GTPase proteins, disrupting the host actin cytoskeleton and enabling bacterial escape...

[]

0

[ "PFAM" ]

[ "PF27349" ]

[ "IcsB_M" ]

[ 432 ]

1

[]

0

[ "5xn7" ]

1

[ "PUB00100643", "PUB00136175", "PUB00162045", "PUB00162046", "PUB00162047", "PUB00162048", "PUB00162049", "PUB00162050", "PUB00162051", "PUB00162052" ]

[ "12753186", "15199181", "30061757", "15576571", "11032799", "11553575", "12045243", "15547287", "16954226", "17474905" ]

[ "IcsB, secreted via the type III secretion system, is chaperoned by IpgA and required at the post-invasion stage of Shigella pathogenicity.", "Identification of a domain within the multifunctional Vibrio cholerae RTX toxin that covalently cross-links actin.", "Nε-fatty acylation of multiple membrane-...

[ 2003, 2004, 2018, 2005, 2000, 2001, 2002, 2004, 2006, 2007 ]

10

[]

0

null

[ "Bacteria", "Opisthokonta", "invertebrate metagenome" ]

[ 388, 43, 1 ]

3

[]

0

true

Domain

IcsB/BopA-like, middle domain

IcsB/BopA_M

4

IPR059884

59,884

Uncharacterised secreted protein ARB_05178

ARB_05178

Family

945

false

This entry represents the ARB_05178 family of uncharacterised secreted proteins found in dermatophytic fungi. The prototype protein from Arthroderma benhamiae is 210 amino acids in length and contains a predicted signal peptide for secretion. The protein has been identified by mass spectrometry in secreted fractions du...

[]

0

[ "PFAM" ]

[ "PF28404" ]

[ "ARB_05178" ]

[ 945 ]

1

[]

0

[]

0

[ "PUB00150849", "PUB00161802" ]

[ "21919205", "21247460" ]

[ "Identification of novel secreted proteases during extracellular proteolysis by dermatophytes at acidic pH.", "Comparative and functional genomics provide insights into the pathogenicity of dermatophytic fungi." ]

[ 2011, 2011 ]

2

[]

0

null

[ "Pezizomycotina" ]

[ 945 ]

1

[ "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)" ]

[ 1 ]

1

true

Family

Uncharacterised secreted protein ARB_05178

ARB_05178

1

IPR059885

59,885

Uncharacterised lipoprotein PM1805

PM1805

Family

537

false

This entry represents the PM1805 family of uncharacterised lipoproteins found in Pasteurella multocida. PM1805 contains an N-terminal signal peptide that is predicted to be processed. The function of this protein remains to be determined.

[]

0

[ "PFAM" ]

[ "PF27255" ]

[ "PM1805" ]

[ 537 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria" ]

[ 537 ]

1

[]

0

true

Family

Uncharacterised lipoprotein PM1805

PM1805

1

IPR059886

59,886

Glucan 1,3-beta-glucosidase 3, C-terminal domain

Exg3_C

Domain

939

false

This entry represents the C-terminal domain of Glucan 1,3- beta-glucosidase 3 (Exg3) and related proteins from fungi. This domain adopts a helix bundle fold and is found in glycoside hydrolases such as glucan 1,3-beta-glucosidase and uncharacterised glycosyl hydrolases. The proteins containing this domain belong to the...

[]

0

[ "PFAM" ]

[ "PF28394" ]

[ "Exg3_C" ]

[ 939 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Fungi" ]

[ 939 ]

1

[ "Saccharomyces cerevisiae (strain ATCC 204508 / S288c)", "Schizosaccharomyces pombe (strain 972 / ATCC 24843)" ]

[ 1, 1 ]

2

true

Domain

Glucan 1,3-beta-glucosidase 3, C-terminal domain

Exg3_C

4

IPR059887

59,887

Uncharacterized protein SSO3021-like, second domain

SSO3021-like_2nd

Domain

181

false

This entry represents the second domain of the uncharacterized protein SSO3021 found in Saccharolobus solfataricus and related archaeal species. Research in this organism has focused on carbohydrate-active enzymes including alpha-xylosidase [ ]. The specific function of this protein and its second domain remains to be ...

[]

0

[ "PFAM" ]

[ "PF27250" ]

[ "SSO3021_2nd" ]

[ 181 ]

1

[]

0

[]

0

[ "PUB00121780" ]

[ "10801892" ]

[ "Identification and molecular characterization of the first alpha -xylosidase from an archaeon." ]

[ 2000 ]

1

[]

0

null

[ "Bacteria", "Thermoprotei", "metagenomes" ]

[ 151, 24, 6 ]

3

[]

0

true

Domain

Uncharacterized protein SSO3021-like, second domain

SSO3021-like_2nd

5

IPR059888

59,888

Phage tail-like, trimerisation region

PTL_trimer

Domain

8,278

false

This entry represents a region that mediates trimerisation and forms a β-spiral region that looks similar to those found in phage tail proteins.

[]

0

[ "PFAM" ]

[ "PF26696" ]

[ "PTL_trimer" ]

[ 8278 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Caudoviricetes", "Opisthokonta", "metagenomes" ]

[ 8156, 54, 12, 56 ]

4

[]

0

true

Domain

Phage tail-like, trimerisation region

PTL_trimer

3

IPR059889

59,889

AF_0136-like, C-terminal domain

AF_0136_C

Domain

180

false

This entry represents the C-terminal domain of the AF_0136 family of uncharacterised proteins found in methanogenic archaea. The family is found across various methanogenic lineages including Methanosarcinaceae, Methanosarcina, and Candidatus Methanoperedenaceae, with some members in Archaeoglobus. The function of this...

[]

0

[ "PFAM" ]

[ "PF27313" ]

[ "AF_0136_C" ]

[ 180 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Archaea", "ecological metagenomes" ]

[ 167, 13 ]

2

[]

0

true

Domain

AF_0136-like, C-terminal domain

AF_0136_C

7

IPR059891

59,891

AF_1859-like, N-terminal domain

AF_1859_N

Domain

834

false

This entry represents the N-terminal domain of AF_1859, an uncharacterised protein from Archaeoglobus fulgidus and related archaeal species. The specific function of this N-terminal domain remains to be determined.

[]

0

[ "PFAM" ]

[ "PF27225" ]

[ "AF_1859_N" ]

[ 834 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Archaea", "Bacteria", "unclassified sequences" ]

[ 23, 788, 23 ]

3

[]

0

true

Domain

AF_1859-like, N-terminal domain

AF_1859_N

1

IPR059892

59,892

Mitochondrial ribosome receptor Mrx15

Mrx15

Family

176

false

This entry represents Mrx15 (YNR040W) from Saccharomyces cerevisiae, a mitochondrial inner membrane protein that functions as a ribosome receptor in fungi. Mrx15 contains two transmembrane segments and interacts with the large subunit (LSU) of the mitoribosome through its positively charged C-terminal domain, which fac...

[]

0

[ "PFAM" ]

[ "PF26669" ]

[ "Mrx15" ]

[ 176 ]

1

[]

0

[]

0

[ "PUB00158822", "PUB00162167" ]

[ "30336542", "30091672" ]

[ "Insertion Defects of Mitochondrially Encoded Proteins Burden the Mitochondrial Quality Control System.", "The ribosome receptors Mrx15 and Mba1 jointly organize cotranslational insertion and protein biogenesis in mitochondria." ]

[ 2018, 2018 ]

2

[]

0

null

[ "Fungi" ]

[ 176 ]

1

[ "Saccharomyces cerevisiae (strain ATCC 204508 / S288c)" ]

[ 1 ]

1

true

Family

Mitochondrial ribosome receptor Mrx15

Mrx15

8

IPR059893

59,893

Type IV pilus biogenesis protein TfpB

TfpB

Family

988

false

This entry represents a family of proteins involved in type IV pilus biogenesis found predominantly in gammaproteobacteria. The prototype protein TfpB from Moraxella bovis is located in the pilin gene inversion region [ ]. Members of this family are approximately 261 amino acids in length and contain multiple N-termina...

[]

0

[ "PFAM" ]

[ "PF27470" ]

[ "TfpB" ]

[ 988 ]

1

[]

0

[]

0

[ "PUB00002105" ]

[ "2403542" ]

[ "Sequence analysis of the inversion region containing the pilin genes of Moraxella bovis." ]

[ 1990 ]

1

[]

0

null

[ "Bacteria", "Viruses" ]

[ 986, 2 ]

2

[]

0

true

Family

Type IV pilus biogenesis protein TfpB

TfpB

9

IPR059894

59,894

KlcB, DNA-binding domain

KlcB_DNA-bd

Domain

154

false

This entry represents the N-terminal domain of KlcB proteins. KlcB proteins are found on IncP plasmids and are involved in transcriptional regulation. This domain is responsible for the DNA-binding activity of the protein [ ]. The protein is part of the kilC operon and its expression is negatively regulated by KorA and...

[]

0

[ "PFAM" ]

[ "PF27393" ]

[ "KlcB_N" ]

[ 154 ]

1

[]

0

[]

0

[ "PUB00055971", "PUB00162117" ]

[ "7773415", "7519596" ]

[ "Evolution of the korA-oriV segment of promiscuous IncP plasmids.", "Structure, expression, and regulation of the kilC operon of promiscuous IncP alpha plasmids." ]

[ 1995, 1994 ]

2

[]

0

null

[ "Bacteria", "plasmids", "viral metagenome" ]

[ 143, 10, 1 ]

3

[]

0

true

Domain

KlcB, DNA-binding domain

KlcB_DNA-bd

3

IPR059895

59,895

AF_1457-like

Family

153

false

This entry represents the AF_1457 family of small uncharacterised proteins found in archaea. The family is predominantly found in methanogenic and hyperthermophilic archaea, including members of the Methanomicrobiaceae, Methanosarcinaceae, and Archaeoglobus. The proteins are approximately 105 amino acids in length and ...

[]

0

[ "PFAM" ]

[ "PF27291" ]

[ "AF_1457" ]

[ 153 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Methanobacteriota", "ecological metagenomes" ]

[ 3, 144, 6 ]

3

[]

0

true

Family

AF_1457-like

1

IPR059896

59,896

Uncharacterized membrane protein AF_0692

AF_0692

Family

457

false

This entry represents the AF_0692 protein family, an uncharacteriesd membrane protein found in Archaeoglobus fulgidus and related archaeal species. The protein contains nine predicted transmembrane helices and is predicted to be a multi-pass membrane protein localised to the cell membrane. The function of this membrane...

[]

0

[ "PFAM" ]

[ "PF27245" ]

[ "AF_0692" ]

[ 457 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Methanobacteriota", "Vitrella brassicaformis", "ecological metagenomes" ]

[ 420, 32, 2, 3 ]

4

[]

0

true

Family

Uncharacterized membrane protein AF_0692

AF_0692

2

IPR059897

59,897

Zinc finger transcription factor ace1/sltA, N-terminal domain

ACE1/SLTA_N

Domain

1,110

false

This entry represents the N-terminal domain of zinc finger transcription factor ace1 and sltA. ACE1 is a Cys2-His2 transcription factor found in fungi that binds to the promoter of the cbh1 gene and activates transcription [ ]. The protein localises to the nucleus and contains three C2H2-type zinc finger domains in its...

[]

0

[ "PFAM" ]

[ "PF28329" ]

[ "ACE1_N" ]

[ 1110 ]

1

[]

0

[]

0

[ "PUB00161780", "PUB00162559" ]

[ "10681571", "33431412" ]

[ "Isolation of the ace1 gene encoding a Cys(2)-His(2) transcription factor involved in regulation of activity of the cellulase promoter cbh1 of Trichoderma reesei.", "The C2H2 Transcription Factor SltA Contributes to Azole Resistance by Coregulating the Expression of the Drug Target Erg11A an...

[ 2000, 2021 ]

2

[]

0

null

[ "Corticicoccus populi", "Eukaryota" ]

[ 1, 1109 ]

2

[ "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)" ]

[ 1 ]

1

true

Domain

Zinc finger transcription factor ace1/sltA, N-terminal domain

ACE1/SLTA_N

7