interpro_id string | interpro_numeric_id int64 | name string | short_name string | entry_type string | protein_count int64 | is_llm bool | is_llm_reviewed bool | abstract string | go_ids list | go_terms list | go_categories list | go_count int64 | member_databases list | member_accessions list | member_names list | member_protein_counts list | member_count int64 | external_databases list | external_accessions list | external_xrefs list | external_xref_count int64 | pdb_ids list | structure_count int64 | publication_ids list | pubmed_ids list | publication_titles list | publication_years list | publication_count int64 | parent_ids list | child_ids list | parent_count int64 | child_count int64 | tree_depth float64 | taxonomy_names list | taxonomy_protein_counts list | taxonomy_count int64 | key_species_names list | key_species_protein_counts list | key_species_count int64 | in_entry_list bool | entry_list_type string | entry_list_name string | names_dat_name string | short_names_dat_name string | split_bucket int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
IPR009465 | 9,465 | Spondin, N-terminal | Spondin_N | Domain | 7,130 | false | false | This conserved region is found in the N-terminal half of several Spondin proteins [ ], also called FS domain. It is found in F-spondins (spondin-1), mindins (spondin-2). Its homology to a common Ca2+- and lipid-binding C2 domain suggests that the F-spondin FS domain is responsible for part of the membrane targeting of ... | [] | [] | [] | 0 | [
"NCBIFAM",
"PFAM",
"PROFILE"
] | [
"NF038123",
"PF06468",
"PS51020"
] | [
"NF038123_dom",
"Spond_N",
"SPONDIN"
] | [
6371,
6106,
5501
] | 3 | [
"PROSITEDOC",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"PDOC51020",
"R-BTA-5173214",
"R-HSA-5083635",
"R-HSA-5173214",
"R-MMU-5173214",
"R-RNO-5173214"
] | [
"PROSITEDOC:PDOC51020",
"REACTOME:R-BTA-5173214",
"REACTOME:R-HSA-5083635",
"REACTOME:R-HSA-5173214",
"REACTOME:R-MMU-5173214",
"REACTOME:R-RNO-5173214"
] | 6 | [
"3d34",
"3q13"
] | 2 | [
"PUB00012620",
"PUB00051224",
"PUB00097423"
] | [
"11287656",
"19153605",
"21569239"
] | [
"F-spondin is a contact-repellent molecule for embryonic motor neurons.",
"Structure of the F-spondin domain of mindin, an integrin ligand and pattern recognition molecule.",
"The structure of the Ca²+-binding, glycosylated F-spondin domain of F-spondin - A C2-domain variant in an extracellular matrix protein."... | [
2001,
2009,
2011
] | 3 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"metagenomes",
"unclassified Klosneuvirinae"
] | [
86,
1735,
5271,
34,
4
] | 5 | [
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
1,
10,
8,
6,
7,
7
] | 6 | true | Domain | Spondin, N-terminal | Spondin, N-terminal | Spondin_N | 5 |
IPR009466 | 9,466 | Non-structural protein 14, coronavirus | NSP14_CoV | Domain | 6,007 | false | false | The unique coronavirus (CoV) transcription/replication machinery comprised of multiple virus-encoded non structural proteins (NSP) plays a vital role during initial and intermediate phases of the viral life cycle. This entry represents NSP14, encoded as part of polyprotein pp1ab and excised by NSP5. Its N-terminal exor... | [
"GO:0004532",
"GO:0008168"
] | [
"RNA exonuclease activity",
"methyltransferase activity"
] | [
"molecular_function",
"molecular_function"
] | 2 | [
"PFAM"
] | [
"PF06471"
] | [
"CoV_ExoN"
] | [
6007
] | 1 | [
"EC",
"EC",
"EC",
"EC",
"EC",
"EC",
"EC",
"EC",
"EC",
"EC",
"GP",
"METACYC",
"METACYC",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACT... | [
"2.1.1.56",
"2.1.1.57",
"2.7.7.48",
"2.7.7.50",
"3.1.13.-",
"3.4.19.12",
"3.4.22.-",
"3.6.4.12",
"3.6.4.13",
"4.6.1.-",
"GenProp1009",
"PWY-7375",
"PWY-7379",
"R-HSA-191859",
"R-HSA-918233",
"R-HSA-9679504",
"R-HSA-9682706",
"R-HSA-9682708",
"R-HSA-9683439",
"R-HSA-9684325",
... | [
"EC:2.1.1.56",
"EC:2.1.1.57",
"EC:2.7.7.48",
"EC:2.7.7.50",
"EC:3.1.13.-",
"EC:3.4.19.12",
"EC:3.4.22.-",
"EC:3.6.4.12",
"EC:3.6.4.13",
"EC:4.6.1.-",
"GP:GenProp1009",
"METACYC:PWY-7375",
"METACYC:PWY-7379",
"REACTOME:R-HSA-191859",
"REACTOME:R-HSA-918233",
"REACTOME:R-HSA-9679504",
... | 29 | [
"5c8s",
"5c8t",
"5c8u",
"5nfy",
"5skw",
"5skx",
"5sky",
"5skz",
"5sl0",
"5sl1",
"5sl2",
"5sl3",
"5sl4",
"5sl5",
"5sl6",
"5sl7",
"5sl8",
"5sl9",
"5sla",
"5slb",
"5slc",
"5sld",
"5sle",
"5slf",
"5slg",
"5slh",
"5sli",
"5slj",
"5slk",
"5sll",
"5slm",
"5sln"... | 106 | [
"PUB00094087",
"PUB00094105",
"PUB00094622",
"PUB00099876",
"PUB00100899",
"PUB00100900",
"PUB00100901"
] | [
"27712628",
"29279395",
"26159422",
"34580920",
"23536667",
"32938769",
"31440227"
] | [
"The Nonstructural Proteins Directing Coronavirus RNA Synthesis and Processing.",
"Structural and molecular basis of mismatch correction and ribavirin excision from coronavirus RNA.",
"Structural basis and functional analysis of the SARS coronavirus nsp14-nsp10 complex.",
"Evolution of the SARS-CoV-2 proteome... | [
2016,
2018,
2015,
2021,
2013,
2020,
2019
] | 7 | [] | [
"IPR044313",
"IPR044315",
"IPR044316",
"IPR044317"
] | 0 | 4 | 0 | [
"Nidovirales"
] | [
6007
] | 1 | [] | [] | 0 | true | Domain | Non-structural protein 14, coronavirus | Non-structural protein 14, coronavirus | NSP14_CoV | 7 |
IPR009467 | 9,467 | Putative glycolipid-binding protein | Glycolipid-bd_prot_put | Family | 3,316 | false | false | This family has a novel fold known as a spiral β-roll, consisting of a 15-stranded β sheet wrapped around a single α helix. It forms dimers. It has some structural similarity to the E. coli lipoprotein localisation factors LolA ( ) and LolB ( ). Its structure suggests that it may have a role in glycolipid binding. Its ... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06475"
] | [
"Glycolipid_bind"
] | [
3316
] | 1 | [] | [] | [] | 0 | [
"2h1t"
] | 1 | [
"PUB00057505"
] | [
"20944213"
] | [
"The structure of the first representative of Pfam family PF06475 reveals a new fold with possible involvement in glycolipid metabolism."
] | [
2010
] | 1 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Opisthokonta",
"metagenomes"
] | [
25,
3214,
40,
37
] | 4 | [] | [] | 0 | true | Family | Putative glycolipid-binding protein | Putative glycolipid-binding protein | Glycolipid-bd_prot_put | 5 |
IPR009468 | 9,468 | Protein of unknown function DUF1090 | DUF1090 | Family | 2,998 | false | false | This family consists of several bacterial proteins of unknown function and is known as YqjC in Escherichia coli. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06476"
] | [
"DUF1090"
] | [
2998
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"metagenomes"
] | [
2989,
2,
7
] | 3 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Protein of unknown function DUF1090 | Protein of unknown function DUF1090 | DUF1090 | 4 |
IPR009469 | 9,469 | RNA-dependent RNA polymerase, N-terminal, coronavirus | RdRp_N_CoV | Domain | 5,474 | false | false | RNA-directed RNA Polymerase corresponds to the nonstructural protein 12 (NSP12) produced by cleavage of ORF1b. NSP12 contains a polymerase domain that assumes a structure resembling a cupped 'right hand', similar to other polymerases, containing a fingers domain, a palm domain and a thumb domain. Coronavirus (CoV) NSP1... | [
"GO:0003723",
"GO:0003968",
"GO:0005524",
"GO:0006351"
] | [
"RNA binding",
"RNA-directed RNA polymerase activity",
"ATP binding",
"DNA-templated transcription"
] | [
"molecular_function",
"molecular_function",
"molecular_function",
"biological_process"
] | 4 | [
"PFAM"
] | [
"PF06478"
] | [
"CoV_RPol_N"
] | [
5474
] | 1 | [
"EC",
"EC",
"EC",
"EC",
"EC",
"EC",
"EC",
"EC",
"EC",
"EC",
"GP",
"METACYC",
"METACYC",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACT... | [
"2.1.1.56",
"2.1.1.57",
"2.7.7.48",
"2.7.7.50",
"3.1.13.-",
"3.4.19.12",
"3.4.22.-",
"3.6.4.12",
"3.6.4.13",
"4.6.1.-",
"GenProp1009",
"PWY-7375",
"PWY-7379",
"R-HSA-191859",
"R-HSA-918233",
"R-HSA-9679504",
"R-HSA-9682706",
"R-HSA-9682708",
"R-HSA-9683439",
"R-HSA-9684325",
... | [
"EC:2.1.1.56",
"EC:2.1.1.57",
"EC:2.7.7.48",
"EC:2.7.7.50",
"EC:3.1.13.-",
"EC:3.4.19.12",
"EC:3.4.22.-",
"EC:3.6.4.12",
"EC:3.6.4.13",
"EC:4.6.1.-",
"GP:GenProp1009",
"METACYC:PWY-7375",
"METACYC:PWY-7379",
"REACTOME:R-HSA-191859",
"REACTOME:R-HSA-918233",
"REACTOME:R-HSA-9679504",
... | 29 | [
"6m71",
"6nur",
"6nus",
"6xez",
"6xqb",
"6yyt",
"7aap",
"7b3b",
"7b3c",
"7b3d",
"7btf",
"7bv1",
"7bv2",
"7bw4",
"7bzf",
"7c2k",
"7ctt",
"7cxm",
"7cxn",
"7cyq",
"7d4f",
"7dfg",
"7dfh",
"7doi",
"7dok",
"7dte",
"7ed5",
"7egq",
"7eiz",
"7krn",
"7kro",
"7krp"... | 88 | [
"PUB00094093",
"PUB00095923",
"PUB00098221",
"PUB00099876",
"PUB00099880",
"PUB00100892",
"PUB00100893",
"PUB00103772"
] | [
"31138817",
"32277040",
"32438371",
"34580920",
"32783916",
"33190493",
"32531208",
"32358203"
] | [
"Structure of the SARS-CoV nsp12 polymerase bound to nsp7 and nsp8 co-factors.",
"Structure of the RNA-dependent RNA polymerase from COVID-19 virus.",
"Structure of replicating SARS-CoV-2 polymerase.",
"Evolution of the SARS-CoV-2 proteome in three dimensions (3D) during the first 6 months of the COVID-19 pan... | [
2019,
2020,
2020,
2021,
2020,
2020,
2020,
2020
] | 8 | [] | [
"IPR047570"
] | 0 | 1 | 0 | [
"Nidovirales"
] | [
5474
] | 1 | [] | [] | 0 | true | Domain | RNA-dependent RNA polymerase, N-terminal, coronavirus | RNA-dependent RNA polymerase, N-terminal, coronavirus | RdRp_N_CoV | 6 |
IPR009471 | 9,471 | Teneurin intracellular, N-terminal | Ten_N | Domain | 9,048 | false | false | This domain is found in the intracellular N-terminal region in Teneurin proteins. Teneurins are a family of phylogenetically conserved transmembrane glycoproteins expressed during pattern formation and morphogenesis [ ]. Originally discovered as ten-m and ten-a in Drosophila melanogaster, the teneurin family is conserv... | [
"GO:0007165",
"GO:0016020"
] | [
"signal transduction",
"membrane"
] | [
"biological_process",
"cellular_component"
] | 2 | [
"PFAM",
"PROFILE"
] | [
"PF06484",
"PS51361"
] | [
"Ten_N",
"TENEURIN_N"
] | [
9037,
8961
] | 2 | [] | [] | [] | 0 | [] | 0 | [
"PUB00009650",
"PUB00012632",
"PUB00014529",
"PUB00014530",
"PUB00014531",
"PUB00043665",
"PUB00043666",
"PUB00043667",
"PUB00066375",
"PUB00066378",
"PUB00155423",
"PUB00155629",
"PUB00155630"
] | [
"10341219",
"12783990",
"11146505",
"12361962",
"10588872",
"16406038",
"17095284",
"17502993",
"23028443",
"21724987",
"29540701",
"29414938",
"25406022"
] | [
"Teneurin-1, a vertebrate homologue of the Drosophila pair-rule gene ten-m, is a neuronal protein with a novel type of heparin-binding domain.",
"The intracellular domain of teneurin-2 has a nuclear function and represses zic-1-mediated transcription.",
"Teneurin-2 is expressed in tissues that regulate limb and... | [
1999,
2003,
2001,
2002,
1999,
2006,
2007,
2007,
2012,
2011,
2018,
2018,
2015
] | 13 | [] | [] | 0 | 0 | null | [
"Vertebrata"
] | [
9048
] | 1 | [
"Danio rerio",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
141,
24,
17,
36
] | 4 | true | Domain | Teneurin intracellular, N-terminal | Teneurin intracellular, N-terminal | Ten_N | 5 |
IPR009472 | 9,472 | Tab2-like | Tab2-like | Family | 1,470 | false | false | Tab2 was first identified in Chlamydomonas reinhardtii as a RNA binding protein required for translation of the chloroplast PsaB photosystem I subunit [ ]. Later, the Tab2 homologue from Arabidopsis was found involved in the signalling pathway of light-controlled synthesis of photosystem proteins during early plant dev... | [
"GO:0003723"
] | [
"RNA binding"
] | [
"molecular_function"
] | 1 | [
"PANTHER"
] | [
"PTHR34556"
] | [
""
] | [
1470
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00083885",
"PUB00083887",
"PUB00098288"
] | [
"14633996",
"17139246",
"25725436"
] | [
"Tab2 is a novel conserved RNA binding protein required for translation of the chloroplast psaB mRNA.",
"ATAB2 is a novel factor in the signalling pathway of light-controlled synthesis of photosystem proteins.",
"Large-scale genetic analysis of chloroplast biogenesis in maize."
] | [
2003,
2006,
2015
] | 3 | [] | [] | 0 | 0 | null | [
"Cyanobacteriota",
"Eukaryota"
] | [
666,
804
] | 2 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
2,
2,
3
] | 3 | true | Family | Tab2-like | Tab2-like | Tab2-like | 1 |
IPR009473 | 9,473 | Orthopoxvirus A49 | Orthopox_A49 | Family | 75 | false | false | This family consists of several Orthopoxvirus A49 proteins. The function of this family is unknown. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06489"
] | [
"Orthopox_A49R"
] | [
75
] | 1 | [] | [] | [] | 0 | [
"4d5r",
"4d5s",
"4d5t"
] | 3 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Chordopoxvirinae"
] | [
75
] | 1 | [] | [] | 0 | true | Family | Orthopoxvirus A49 | Orthopoxvirus A49 | Orthopox_A49 | 9 |
IPR009474 | 9,474 | Bacilliredoxins BrxB/BrxA | BrxB/BrxA | Family | 4,562 | false | false | S-bacillithiolation is the formation of mixed disulfide bonds between protein thiols and the general thiol reductant bacillithiol (BSH) under oxidative stress. BSH is an equivalent of glutathione (GSH) in Firmicutes [ , , ]. This protein family includes the bacilliredoxins BrxA and BrxB (previously known as YphP and Yq... | [] | [] | [] | 0 | [
"PFAM",
"PANTHER",
"NCBIFAM"
] | [
"PF06491",
"PTHR40052",
"TIGR04191"
] | [
"Disulph_isomer",
"",
"YphP_YqiW"
] | [
4562,
4557,
4544
] | 3 | [
"GP"
] | [
"GenProp0933"
] | [
"GP:GenProp0933"
] | 1 | [
"3fhk",
"7rzb"
] | 2 | [
"PUB00052908",
"PUB00070740",
"PUB00070741",
"PUB00070742",
"PUB00100774"
] | [
"19653655",
"21749987",
"20712413",
"22938038",
"24313874"
] | [
"Structure and function of Bacillus subtilis YphP, a prokaryotic disulfide isomerase with a CXC catalytic motif .",
"S-bacillithiolation protects against hypochlorite stress in Bacillus subtilis as revealed by transcriptomics and redox proteomics.",
"Bacillithiol, a new player in bacterial redox homeostasis.",
... | [
2009,
2011,
2011,
2013,
2014
] | 5 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Candidatus Iainarchaeum sp.",
"Metazoa",
"metagenomes"
] | [
4532,
1,
5,
24
] | 4 | [] | [] | 0 | true | Family | Bacilliredoxins BrxB/BrxA | Bacilliredoxins BrxB/BrxA | BrxB/BrxA | 8 |
IPR009475 | 9,475 | Protein of unknown function DUF1096 | DUF1096 | Family | 67 | false | false | This family of unknown function consists of several proteins found in Caenorhabditis. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06493"
] | [
"DUF1096"
] | [
67
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Rhabditomorpha"
] | [
67
] | 1 | [
"Caenorhabditis elegans"
] | [
6
] | 1 | true | Family | Protein of unknown function DUF1096 | Protein of unknown function DUF1096 | DUF1096 | 4 |
IPR009477 | 9,477 | Baculovirus Ac102 | Baculo_Ac102 | Family | 118 | false | false | This family of baculovirus proteins is represented by Autographa californica nuclear polyhedrosis virus (AcMNPV) Ac102. Nuclear actin is critical for AcMNPV progeny production, and Ac102 plays an essential role in actin translocation to the nucleus [ ]. It plays a role in regulating nuclear actin polymerization as well... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06497"
] | [
"Baculo_Ac102"
] | [
118
] | 1 | [] | [] | [] | 0 | [
"9h2k"
] | 1 | [
"PUB00082590",
"PUB00097494",
"PUB00097495"
] | [
"22592260",
"29618641",
"29540600"
] | [
"Nuclear localization of actin requires AC102 in Autographa californica multiple nucleopolyhedrovirus-infected cells.",
"Ac102 Participates in Nuclear Actin Polymerization by Modulating BV/ODV-C42 Ubiquitination during Autographa californica Multiple Nucleopolyhedrovirus Infection.",
"Baculovirus AC102 Is a Nuc... | [
2012,
2018,
2018
] | 3 | [] | [] | 0 | 0 | null | [
"Baculoviridae"
] | [
118
] | 1 | [] | [] | 0 | true | Family | Baculovirus Ac102 | Baculovirus Ac102 | Baculo_Ac102 | 8 |
IPR009479 | 9,479 | Human herpesvirus U55 | Herpes_U55 | Family | 53 | false | false | This family consists of several human herpesvirus U55 proteins. The function of this family is unknown. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06501"
] | [
"Herpes_U55"
] | [
53
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota",
"Roseolovirus"
] | [
7,
46
] | 2 | [
"Homo sapiens"
] | [
1
] | 1 | true | Family | Human herpesvirus U55 | Human herpesvirus U55 | Herpes_U55 | 8 |
IPR009482 | 9,482 | Protein of unknown function DUF1102 | DUF1102 | Family | 327 | false | false | This family consists of proteins of unknown function. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06510"
] | [
"DUF1102"
] | [
327
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacillales",
"viral metagenome"
] | [
322,
4,
1
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF1102 | Protein of unknown function DUF1102 | DUF1102 | 2 |
IPR009485 | 9,485 | Borna disease virus P10 | BDV_P10 | Family | 91 | false | false | This family consists of several Borna disease virus P10 (or X) proteins. Borna disease virus (BDV) is unique among the non-segmented negative-strand RNA viruses of animals and man because it transcribes and replicates its genome in the nucleus of the infected cell. It has been suggested that the p10 protein plays a rol... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06515"
] | [
"BDV_P10"
] | [
91
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00012637"
] | [
"10725419"
] | [
"A short leucine-rich sequence in the Borna disease virus p10 protein mediates association with the viral phospho- and nucleoproteins."
] | [
2000
] | 1 | [] | [] | 0 | 0 | null | [
"Bornaviridae"
] | [
91
] | 1 | [] | [] | 0 | true | Family | Borna disease virus P10 | Borna disease virus P10 | BDV_P10 | 4 |
IPR009486 | 9,486 | Purine nucleoside permease | Pur_nuclsid_perm | Family | 3,292 | false | false | This family consists of several purine nucleoside permease from both bacteria and fungi [ ]. They are nucleoside permeases that transports adenosine and guanosine and does not show any transport activities towards cytidine, adenine, guanine, uridine, and uracil [ ] | [
"GO:0055085"
] | [
"transmembrane transport"
] | [
"biological_process"
] | 1 | [
"PFAM",
"PIRSF",
"PANTHER"
] | [
"PF06516",
"PIRSF013171",
"PTHR38643"
] | [
"NUP",
"Pur_nuclsid_perm",
""
] | [
3291,
2490,
3261
] | 3 | [] | [] | [] | 0 | [] | 0 | [
"PUB00012638"
] | [
"9802205"
] | [
"Cloning of the Candida albicans nucleoside transporter by complementation of nucleoside transport-deficient Saccharomyces."
] | [
1998
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Halobacteriales",
"ecological metagenomes"
] | [
1729,
1485,
71,
7
] | 4 | [
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Schizosaccharomyces pombe (strain 972 / ATCC 24843)"
] | [
1,
1
] | 2 | true | Family | Purine nucleoside permease | Purine nucleoside permease | Pur_nuclsid_perm | 3 |
IPR009487 | 9,487 | Orthopoxvirus A43R | Orthopox_A43R | Family | 94 | false | false | This family consists of several Orthopoxvirus A43R proteins. The function of this family is unknown. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06517"
] | [
"Orthopox_A43R"
] | [
94
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Chordopoxvirinae"
] | [
94
] | 1 | [] | [] | 0 | true | Family | Orthopoxvirus A43R | Orthopoxvirus A43R | Orthopox_A43R | 9 |
IPR009489 | 9,489 | PAR1 | PAR1 | Family | 2,237 | false | false | This family consists of several plant specific PAR1 proteins from Nicotiana tabacum (Common tobacco) and Arabidopsis thaliana (Mouse-ear cress). The function of this family is unknown. | [] | [] | [] | 0 | [
"PFAM",
"PANTHER"
] | [
"PF06521",
"PTHR33649"
] | [
"PAR1",
""
] | [
2237,
2197
] | 2 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Embryophyta"
] | [
2237
] | 1 | [
"Arabidopsis thaliana",
"Zea mays"
] | [
9,
8
] | 2 | true | Family | PAR1 | PAR1 | PAR1 | 6 |
IPR009490 | 9,490 | Protein of unknown function DUF1106 | DUF1106 | Family | 58 | false | false | This family consists of several hypothetical bacterial proteins found in Enterobacterales. The function of this family is unknown. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06523"
] | [
"DUF1106"
] | [
58
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Enterobacterales"
] | [
58
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF1106 | Protein of unknown function DUF1106 | DUF1106 | 9 |
IPR009491 | 9,491 | Protein of unknown function DUF1107 | DUF1107 | Family | 1,711 | false | false | This family consists of several short, hypothetical bacterial proteins of unknown function. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06526"
] | [
"DUF1107"
] | [
1711
] | 1 | [] | [] | [] | 0 | [
"2jro"
] | 1 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"bioreactor metagenome"
] | [
1710,
1
] | 2 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Protein of unknown function DUF1107 | Protein of unknown function DUF1107 | DUF1107 | 7 |
IPR009492 | 9,492 | TniQ | TniQ | Domain | 6,860 | false | false | This entry consists of several bacterial TniQ proteins. TniQ along with TniA and B is involved in the transposition of the mercury-resistance transposon Tn5053 that carries the mer operon. It has been suggested that the tni genes are involved in the dissemination of integrons [ ]. This entry also includes TnsD from E. ... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06527"
] | [
"TniQ"
] | [
6860
] | 1 | [] | [] | [] | 0 | [
"6lnb",
"6lnc",
"6lnd",
"6pif",
"6pig",
"6pij",
"6uvn",
"6v9p",
"6v9q",
"6vbw",
"7n6i",
"7oxd",
"7svu",
"7u5d",
"7u5e",
"8bd4",
"8bd5",
"8ea3",
"8ea4",
"8fcu",
"8fcv",
"8ff4",
"8fuk",
"8glu",
"8glw",
"8glx",
"8rdu",
"8rkt",
"8v32",
"8vcj",
"8vct",
"9bw1"... | 33 | [
"PUB00011500",
"PUB00075407"
] | [
"8594337",
"2156235"
] | [
"Four genes, two ends, and a res region are involved in transposition of Tn5053: a paradigm for a novel family of transposons carrying either a mer operon or an integron.",
"DNA sequence analysis of five genes; tnsA, B, C, D and E, required for Tn7 transposition."
] | [
1995,
1990
] | 2 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"metagenomes",
"plasmids"
] | [
6822,
5,
29,
4
] | 4 | [] | [] | 0 | true | Domain | TniQ | TniQ | TniQ | 5 |
IPR009494 | 9,494 | Protein of unknown function DUF1108 | DUF1108 | Family | 237 | false | false | This entry includes Bacteriophage 92, Orf49. The characteristics of the protein distribution suggest prophage matches in addition to the phage matches. This family consists of several bacterial proteins from Staphylococcus aureus as well as a number of phage proteins. The function of this family is unknown. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06531"
] | [
"DUF1108"
] | [
237
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillales",
"Viruses"
] | [
134,
103
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function DUF1108 | Protein of unknown function DUF1108 | DUF1108 | 3 |
IPR009495 | 9,495 | Anti-sigma-F factor NrsF | NrsF | Family | 2,623 | false | false | This entry includes anti-sigma-F factor NrsF from Caulobacter crescentus , which is thought to be an anti-sigma factor for sigma F. Caulobacter crescentus survives where nutrients are low and where the concentration of heavy metals are high, and it is able to do so by altering the expression of a large number of genes.... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06532"
] | [
"NrsF"
] | [
2623
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00086036"
] | [
"22985357"
] | [
"Extracytoplasmic function (ECF) sigma factor σF is involved in Caulobacter crescentus response to heavy metal stress."
] | [
2012
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"metagenomes"
] | [
2608,
4,
11
] | 3 | [] | [] | 0 | true | Family | Anti-sigma-F factor NrsF | Anti-sigma-F factor NrsF | NrsF | 3 |
IPR009496 | 9,496 | Repulsive guidance molecule, C-terminal | RGM_C | Domain | 3,548 | false | false | This entry represents the C-terminal domain of repulsive guidance molecule (RGM) mainly found in animals. This domain is responsible for neogenin (NEO1) binding [ , ]. This domain contains a β-sandwich structure. In some proteins, this domain encompasses the entire protein. RGM is a GPI-linked axon guidance molecule of... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06534"
] | [
"RGM_C"
] | [
3548
] | 1 | [
"REACTOME"
] | [
"R-HSA-373752"
] | [
"REACTOME:R-HSA-373752"
] | 1 | [
"4bq6",
"4bq7",
"4bq8",
"4ui2",
"6z3m",
"7ndg",
"7ne0"
] | 7 | [
"PUB00012643",
"PUB00079264",
"PUB00100686"
] | [
"12353034",
"25938661",
"33740419"
] | [
"RGM is a repulsive guidance molecule for retinal axons.",
"Repulsive guidance molecule is a structural bridge between neogenin and bone morphogenetic protein.",
"Simultaneous binding of Guidance Cues NET1 and RGM blocks extracellular NEO1 signaling."
] | [
2002,
2015,
2021
] | 3 | [] | [] | 0 | 0 | null | [
"Cyanophyceae",
"Eukaryota",
"bird metagenome"
] | [
2,
3545,
1
] | 3 | [
"Caenorhabditis elegans",
"Danio rerio",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
1,
6,
12,
7,
11
] | 5 | true | Domain | Repulsive guidance molecule, C-terminal | Repulsive guidance molecule, C-terminal | RGM_C | 6 |
IPR009497 | 9,497 | Regulator protein, PHA-1 | Regulator_protein_PHA-1 | Family | 230 | false | false | This family represents the protein product of the gene pha-1 which coordinates with lin-35 Rb during animal development. The protein is expressed during embryonic development and functions in the cytoplasm. PHA-1 acts in a parallel pathway with UBC-18 to regulate the activity of a common cellular target [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06542"
] | [
"PHA-1"
] | [
230
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00053702"
] | [
"15196946"
] | [
"The coordinate regulation of pharyngeal development in C. elegans by lin-35/Rb, pha-1, and ubc-18."
] | [
2004
] | 1 | [] | [] | 0 | 0 | null | [
"Caenorhabditis"
] | [
230
] | 1 | [
"Caenorhabditis elegans"
] | [
15
] | 1 | true | Family | Regulator protein, PHA-1 | Regulator protein, PHA-1 | Regulator_protein_PHA-1 | 9 |
IPR009498 | 9,498 | Bacteriophage 4268, Orf1, C-terminal | Phage_4268_Orf1_C | Domain | 146 | false | false | This entry represents the C terminus of various Lactococcus bacteriophage repressor proteins. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06543"
] | [
"Lac_bphage_repr"
] | [
146
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Lactobacillales",
"unclassified Caudoviricetes"
] | [
144,
2
] | 2 | [] | [] | 0 | true | Domain | Bacteriophage 4268, Orf1, C-terminal | Bacteriophage 4268, Orf1, C-terminal | Phage_4268_Orf1_C | 1 |
IPR009499 | 9,499 | Oxamate carbamoyltransferase subunit AllG-like | AllG-like | Family | 3,185 | false | false | This entry, previously known ad DUF1116, represents Oxamate carbamoyltransferase subunit AllG and related bacterial proteins. AllG is a component of a carbamoyltransferase involved in the anaerobic nitrogen utilisation via the assimilation of allantoin [ ]. It is catalyses the conversion of oxalurate (N-carbamoyl-2-oxo... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06545"
] | [
"AllG"
] | [
3185
] | 1 | [] | [] | [] | 0 | [
"3clq"
] | 1 | [
"PUB00155434"
] | [
"38888336"
] | [
"Oxamic transcarbamylase of <i>Escherichia coli</i> is encoded by the three genes <i>allFGH</i> (formerly <i>fdrA, ylbE</i>, and <i>ylbF</i>)."
] | [
2024
] | 1 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"metagenomes"
] | [
21,
3060,
13,
91
] | 4 | [
"Escherichia coli (strain K12)"
] | [
2
] | 1 | true | Family | Oxamate carbamoyltransferase subunit AllG-like | Oxamate carbamoyltransferase subunit AllG-like | AllG-like | 1 |
IPR009500 | 9,500 | Protein of unknown function DUF1118 | DUF1118 | Family | 1,219 | false | false | This family consists of several hypothetical plant proteins of unknown function. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06549"
] | [
"DUF1118"
] | [
1219
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [
"IPR016801"
] | 0 | 1 | 0 | [
"Eukaryota",
"Paeniglutamicibacter sulfureus"
] | [
1218,
1
] | 2 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
5,
8,
6
] | 3 | true | Family | Protein of unknown function DUF1118 | Protein of unknown function DUF1118 | DUF1118 | 1 |
IPR009501 | 9,501 | Uncharacterised conserved protein UCP020269 | UCP020269 | Family | 1,472 | false | false | This family consists of several hypothetical proteins from bacteria and from Dictyostelium discoideum (Slime mold). The function of this family is unknown. | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF020269"
] | [
"DUF1121"
] | [
1472
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"ecological metagenomes"
] | [
50,
1396,
5,
21
] | 4 | [] | [] | 0 | true | Family | Uncharacterised conserved protein UCP020269 | Uncharacterised conserved protein UCP020269 | UCP020269 | 9 |
IPR009502 | 9,502 | Secretion monitor | SecM | Family | 1,393 | false | false | This family consists of several bacterial Secretion monitor precursor (SecM) proteins. SecM is known to regulate SecA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that... | [
"GO:0045182"
] | [
"translation regulator activity"
] | [
"molecular_function"
] | 1 | [
"HAMAP",
"NCBIFAM",
"PFAM",
"PIRSF"
] | [
"MF_01332",
"NF002799",
"PF06558",
"PIRSF004572"
] | [
"SecM",
"PRK02943.1-1",
"SecM",
"SecM"
] | [
1317,
1379,
1393,
1198
] | 4 | [] | [] | [] | 0 | [
"8qoa"
] | 1 | [
"PUB00012653",
"PUB00097606",
"PUB00104124"
] | [
"10986266",
"21635582",
"25908824"
] | [
"Revised translation start site for secM defines an atypical signal peptide that regulates Escherichia coli secA expression.",
"The translational regulatory function of SecM requires the precise timing of membrane targeting.",
"Ribosome. Mechanical force releases nascent chain-mediated ribosome arrest in vitro ... | [
2000,
2011,
2015
] | 3 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Nematoda",
"bioreactor metagenome"
] | [
1390,
2,
1
] | 3 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Secretion monitor | Secretion monitor | SecM | 8 |
IPR009503 | 9,503 | Protein of unknown function DUF1125 | DUF1125 | Family | 42 | false | false | This family consists of several short proteins from Lactococcus species and bacteriophages. The function of this family is unknown. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06563"
] | [
"DUF1125"
] | [
42
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Lactococcus",
"unclassified Caudoviricetes"
] | [
40,
2
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function DUF1125 | Protein of unknown function DUF1125 | DUF1125 | 5 |
IPR009505 | 9,505 | Neural chondroitin sulphate proteoglycan cytoplasmic | Neural_ProG_Cyt | Domain | 1,343 | false | false | This entry represents the C-terminal cytoplasmic domain of vertebrate neural chondroitin sulphate proteoglycans that contain EGF modules. Evidence has been accumulated to support the idea that neural proteoglycans are involved in various cellular events including mitogenesis, differentiation, axonal outgrowth and synap... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06567"
] | [
"Neural_ProG_Cyt"
] | [
1343
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-HSA-1971475",
"R-HSA-2022870",
"R-HSA-2022923",
"R-HSA-2024101",
"R-HSA-3560783",
"R-HSA-3560801",
"R-HSA-3595172",
"R-HSA-3595174",
"R-HSA-3595177",
"R-HSA-4420332",
"R-MMU-1971475",
"R-MMU-2022870",
"R-MMU-2022923",
"R-MMU-2024101",
"R-RNO-1971475",
"R-RNO-2022870",
"R-RNO-20229... | [
"REACTOME:R-HSA-1971475",
"REACTOME:R-HSA-2022870",
"REACTOME:R-HSA-2022923",
"REACTOME:R-HSA-2024101",
"REACTOME:R-HSA-3560783",
"REACTOME:R-HSA-3560801",
"REACTOME:R-HSA-3595172",
"REACTOME:R-HSA-3595174",
"REACTOME:R-HSA-3595177",
"REACTOME:R-HSA-4420332",
"REACTOME:R-MMU-1971475",
"REACTOM... | 18 | [] | 0 | [
"PUB00012654",
"PUB00012655"
] | [
"9321696",
"9950058"
] | [
"Chondroitin sulfate proteoglycans as mediators of axon growth and pathfinding.",
"Cloning and chromosomal mapping of the human gene of neuroglycan C (NGC), a neural transmembrane chondroitin sulfate proteoglycan with an EGF module."
] | [
1997,
1998
] | 2 | [] | [] | 0 | 0 | null | [
"Vertebrata"
] | [
1343
] | 1 | [
"Danio rerio",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
27,
2,
1,
5
] | 4 | true | Domain | Neural chondroitin sulphate proteoglycan cytoplasmic | Neural chondroitin sulphate proteoglycan cytoplasmic | Neural_ProG_Cyt | 4 |
IPR009506 | 9,506 | YjiS-like domain | YjiS-like | Domain | 12,419 | false | false | This arginine rich domain is found at the C-terminal end of YjiS from Salmonella Typhimurium ( ), YjiS from Escherichia coli and similar short sequences from proteobacteria. In S.Typhimurium, this inner membrane-associated small protein acts as a suppressor of flagella production, leading to pathogen escape from infect... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06568"
] | [
"YjiS-like"
] | [
12419
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00160926",
"PUB00160927",
"PUB00160928",
"PUB00160929",
"PUB00160930",
"PUB00160932",
"PUB00162558"
] | [
"14744977",
"32839178",
"33093235",
"33706375",
"39790481",
"37298460",
"41064459"
] | [
"Cassette-like variation of restriction enzyme genes in Escherichia coli C and relatives.",
"Short, Rich, and Powerful: a New Family of Arginine-Rich Small Proteins Have Outsized Impact in Agrobacterium tumefaciens.",
"Arginine-Rich Small Proteins with a Domain of Unknown Function, DUF1127, Play a Role in Phosp... | [
2004,
2020,
2020,
2021,
2025,
2023,
2025
] | 7 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Caudoviricetes",
"ecological metagenomes"
] | [
12353,
19,
47
] | 3 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Domain | YjiS-like domain | YjiS-like domain | YjiS-like | 5 |
IPR009507 | 9,507 | Protein of unknown function UPF0435 | UPF0435 | Family | 1,550 | false | false | This family consists of several short, hypothetical bacterial proteins of unknown function. | [] | [] | [] | 0 | [
"HAMAP",
"PFAM"
] | [
"MF_00829",
"PF06569"
] | [
"UPF0435",
"DUF1128"
] | [
827,
1550
] | 2 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacilli",
"Phytophthora kernoviae 00238/432",
"human gut metagenome"
] | [
1548,
1,
1
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function UPF0435 | Protein of unknown function UPF0435 | UPF0435 | 8 |
IPR009509 | 9,509 | Protein of unknown function DUF1132 | DUF1132 | Family | 34 | false | false | This family consists of several hypothetical proteins from Neisseria species. The function of this family is unknown. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06575"
] | [
"DUF1132"
] | [
34
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Neisseriaceae"
] | [
34
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF1132 | Protein of unknown function DUF1132 | DUF1132 | 4 |
IPR009510 | 9,510 | Type III secretion system, secretion protein K | T3SS_K | Family | 443 | false | false | This family consists of secretion proteins like Yersinia YscK. The function of this protein is unknown but it belongs to an operon involved in the secretion of Yop proteins across bacterial membranes [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06578"
] | [
"YscK"
] | [
443
] | 1 | [
"GP"
] | [
"GenProp0052"
] | [
"GP:GenProp0052"
] | 1 | [
"6uie"
] | 1 | [
"PUB00020581"
] | [
"1860816"
] | [
"Analysis of virC, an operon involved in the secretion of Yop proteins by Yersinia enterocolitica."
] | [
1991
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria",
"metagenomes"
] | [
441,
2
] | 2 | [] | [] | 0 | true | Family | Type III secretion system, secretion protein K | Type III secretion system, secretion protein K | T3SS_K | 4 |
IPR009511 | 9,511 | Mad1/Cdc20-bound-Mad2 binding protein | MAD1/Cdc20-bound-Mad2-bd | Family | 2,035 | false | false | This entry represents Mad1 and Cdc20-bound-Mad2 binding proteins that are involved in the cell-cycle surveillance mechanism called the spindle checkpoint [ ]. This mechanism monitors the proper bipolar attachment of sister chromatids to spindle microtubules and ensures the fidelity of chromosome segregation during mito... | [
"GO:0007096",
"GO:0005634"
] | [
"regulation of exit from mitosis",
"nucleus"
] | [
"biological_process",
"cellular_component"
] | 2 | [
"PFAM",
"PANTHER"
] | [
"PF06581",
"PTHR15681"
] | [
"p31comet",
""
] | [
1243,
2020
] | 2 | [] | [] | [] | 0 | [
"2qyf",
"6f0x"
] | 2 | [
"PUB00049186",
"PUB00053369"
] | [
"18022368",
"12456649"
] | [
"p31comet blocks Mad2 activation through structural mimicry.",
"Identification of a MAD2-binding protein, CMT2, and its role in mitosis."
] | [
2007,
2002
] | 2 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
2035
] | 1 | [
"Arabidopsis thaliana",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Zea mays"
] | [
7,
1,
1,
1,
4,
3,
2,
7
] | 8 | true | Family | Mad1/Cdc20-bound-Mad2 binding protein | Mad1/Cdc20-bound-Mad2 binding protein | MAD1/Cdc20-bound-Mad2-bd | 1 |
IPR009513 | 9,513 | PerB | PerB | Family | 15 | false | false | This family consists of several PerB or BfpV proteins found specifically in Escherichia coli. PerB is thought to play a role in regulating the expression of BfpA [ ]. | [] | [] | [] | 0 | [
"PFAM",
"PIRSF"
] | [
"PF06590",
"PIRSF009562"
] | [
"PerB",
"PerB"
] | [
15,
8
] | 2 | [] | [] | [] | 0 | [] | 0 | [
"PUB00012250"
] | [
"7729884"
] | [
"A plasmid-encoded regulatory region activates chromosomal eaeA expression in enteropathogenic Escherichia coli."
] | [
1995
] | 1 | [] | [] | 0 | 0 | null | [
"Escherichia coli"
] | [
15
] | 1 | [] | [] | 0 | true | Family | PerB | PerB | PerB | 6 |
IPR009514 | 9,514 | Nucleoid disruption protein | Phage_Ndd | Family | 307 | false | false | This family consists of several nuclear disruption (Ndd) proteins from T4-like phages. Early in a Bacteriophage T4 infection, the phage ndd gene causes the rapid destruction of the structure of the Escherichia coli nucleoid. The targets of Ndd action may be the chromosomal sequences that determine the structure of the ... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06591"
] | [
"Phage_T4_Ndd"
] | [
307
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00012752"
] | [
"9748458"
] | [
"Ndd, the bacteriophage T4 protein that disrupts the Escherichia coli nucleoid, has a DNA binding activity."
] | [
1998
] | 1 | [] | [] | 0 | 0 | null | [
"Pseudomonadati",
"Viruses"
] | [
2,
305
] | 2 | [] | [] | 0 | true | Family | Nucleoid disruption protein | Nucleoid disruption protein | Phage_Ndd | 9 |
IPR009515 | 9,515 | Protein of unknown function DUF1138 | DUF1138 | Family | 990 | false | false | This family consists of several hypothetical short plant proteins from Arabidopsis thaliana and Oryza sativa. The function of this family is unknown. | [] | [] | [] | 0 | [
"PFAM",
"PANTHER"
] | [
"PF06592",
"PTHR34267"
] | [
"DUF1138",
""
] | [
990,
923
] | 2 | [] | [] | [] | 0 | [
"7jro",
"7jrp"
] | 2 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
990
] | 1 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
9,
11,
4
] | 3 | true | Family | Protein of unknown function DUF1138 | Protein of unknown function DUF1138 | DUF1138 | 4 |
IPR009516 | 9,516 | Raspberry bushy dwarf virus coat | RBDV_coat | Family | 60 | false | false | This family consists of several Raspberry bushy dwarf virus (RBDV) coat proteins. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06593"
] | [
"RBDV_coat"
] | [
60
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Idaeovirus"
] | [
60
] | 1 | [] | [] | 0 | true | Family | Raspberry bushy dwarf virus coat | Raspberry bushy dwarf virus coat | RBDV_coat | 7 |
IPR009517 | 9,517 | Borna disease virus P24 | BDV_P24 | Family | 153 | false | false | Borna disease virus (BDV) is a non-cytolytic, neurotropic RNA virus that has a broad host range in warm-blooded animals. BDV is an enveloped virus, non-segmented, negative-stranded RNA genome and has an organisation characteristic of a member of Bornaviridae in the order of Mononegavirale. This family consists of sever... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06595"
] | [
"BDV_P24"
] | [
153
] | 1 | [] | [] | [] | 0 | [
"8b8a",
"8b8b",
"8b8d",
"8bs7",
"9h1g",
"9h1q",
"9h1y",
"9n0q",
"9n0r",
"9n0s",
"9n0t",
"9n0u"
] | 12 | [
"PUB00043634",
"PUB00043635",
"PUB00043636",
"PUB00043637",
"PUB00043638"
] | [
"14581561",
"8523585",
"9811743",
"18623121",
"16324750"
] | [
"Borna disease virus phosphoprotein represses p53-mediated transcriptional activity by interference with HMGB1.",
"Sequence variability of Borna disease virus open reading frame II found in human peripheral blood mononuclear cells.",
"Detection and sequence analysis of borna disease virus p24 RNA from periphera... | [
2003,
1996,
1998,
2008,
2006
] | 5 | [] | [] | 0 | 0 | null | [
"Bornaviridae",
"Toxicofera"
] | [
151,
2
] | 2 | [] | [] | 0 | true | Family | Borna disease virus P24 | Borna disease virus P24 | BDV_P24 | 6 |
IPR009518 | 9,518 | Photosystem II PsbX | PSII_PsbX | Family | 1,879 | false | false | The low molecular weight transmembrane protein PsbX found in PSII is associated with the oxygen-evolving complex. Its expression is light-regulated. PsbX appears to be involved in the regulation of the amount of PSII [ ], and may be involved in the binding or turnover of quinone molecules at the Qb (PsbA) site [ ]. Oxy... | [
"GO:0015979",
"GO:0009523",
"GO:0016020"
] | [
"photosynthesis",
"photosystem II",
"membrane"
] | [
"biological_process",
"cellular_component",
"cellular_component"
] | 3 | [
"PFAM"
] | [
"PF06596"
] | [
"PsbX"
] | [
1879
] | 1 | [
"GP"
] | [
"GenProp0661"
] | [
"GP:GenProp0661"
] | 1 | [
"1s5l",
"3a0b",
"3a0h",
"3jcu",
"3kzi",
"3wu2",
"4fby",
"4il6",
"4ixq",
"4ixr",
"4pbu",
"4pj0",
"4rvy",
"4tnh",
"4tni",
"4tnj",
"4tnk",
"4ub6",
"4ub8",
"4v62",
"4v82",
"4yuu",
"5b5e",
"5b66",
"5e79",
"5e7c",
"5gth",
"5gti",
"5h2f",
"5kaf",
"5kai",
"5mdx"... | 161 | [
"PUB00014965",
"PUB00015357",
"PUB00015358",
"PUB00015359",
"PUB00015378",
"PUB00097583",
"PUB00152828"
] | [
"11230572",
"12518057",
"15100025",
"14871485",
"11202442",
"30076221",
"33846594"
] | [
"Targeted disruption of psbX and biochemical characterization of photosystem II complex in the thermophilic cyanobacterium Synechococcus elongatus.",
"Crystal structure of oxygen-evolving photosystem II from Thermosynechococcus vulcanus at 3.7-A resolution.",
"The evolutionary development of the protein complem... | [
2001,
2003,
2004,
2004,
2000,
2018,
2021
] | 7 | [] | [
"IPR023428",
"IPR023431"
] | 0 | 2 | 0 | [
"Bacillati",
"Eukaryota",
"marine metagenome"
] | [
335,
1543,
1
] | 3 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
4,
8,
11
] | 3 | true | Family | Photosystem II PsbX | Photosystem II PsbX | PSII_PsbX | 8 |
IPR009519 | 9,519 | Fiji disease virus, Vp7-2 | FDV_Vp7-2 | Family | 55 | false | false | This family consists of several hypothetical Fijivirus proteins of unknown function. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06599"
] | [
"DUF1139"
] | [
55
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Fijivirus",
"Xenorhabdus bovienii"
] | [
53,
2
] | 2 | [] | [] | 0 | true | Family | Fiji disease virus, Vp7-2 | Fiji disease virus, Vp7-2 | FDV_Vp7-2 | 7 |
IPR009520 | 9,520 | Protein of unknown function DUF1140 | DUF1140 | Family | 172 | false | false | This family consists of several short, hypothetical phage and bacterial proteins. The function of this family is unknown. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06600"
] | [
"DUF1140"
] | [
172
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacilli",
"Viruses"
] | [
89,
83
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function DUF1140 | Protein of unknown function DUF1140 | DUF1140 | 7 |
IPR009521 | 9,521 | Orthopoxvirus F6 | Orthopox_F6 | Family | 56 | false | false | This family consists of several Orthopoxvirus F6L proteins the function of which is unknown. F6L is also known as Protein OPG050. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06601"
] | [
"Orthopox_F6"
] | [
56
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Chordopoxvirinae"
] | [
56
] | 1 | [] | [] | 0 | true | Family | Orthopoxvirus F6 | Orthopoxvirus F6 | Orthopox_F6 | 1 |
IPR009522 | 9,522 | Nucleocapsid, Phlebovirus/Tenuivirus | Capsid_Phlebovir/Tenuivir | Family | 1,620 | false | false | This entry represents nucleocapsid proteins from the ssRNA viruses Tenuivirus and Phlebovirus [ , ]. These are ssRNA viruses. In crystal structures, the nucleocapsid protein from the Rift Valley fever virus (RVFV) displays a ring-shaped oligomeric assembly [ ]. Electron microscopy (EM) also demonstrates that, in comple... | [
"GO:0003723"
] | [
"RNA binding"
] | [
"molecular_function"
] | 1 | [
"PFAM"
] | [
"PF05733"
] | [
"Tenui_N"
] | [
1620
] | 1 | [] | [] | [] | 0 | [
"3lyf",
"3ouo",
"3ov9",
"4csf",
"4csg",
"4h5l",
"4h5m",
"4h5o",
"4h5p",
"4h5q",
"4j4r",
"4j4s",
"4j4u",
"4j4v",
"4j4w",
"4j4x",
"4j4y",
"4v9e",
"5fva",
"8rcq",
"9umz"
] | 21 | [
"PUB00011495",
"PUB00020107",
"PUB00094271",
"PUB00094272"
] | [
"2024478",
"1846496",
"21589902",
"20547879"
] | [
"Nucleotide sequence and RNA hybridization analyses reveal an ambisense coding strategy for maize stripe virus RNA3.",
"Sequences and coding strategies of the S RNAs of Toscana and Rift Valley fever viruses compared to those of Punta Toro, Sicilian Sandfly fever, and Uukuniemi viruses.",
"The hexamer structure ... | [
1991,
1991,
2011,
2010
] | 4 | [] | [
"IPR015971"
] | 0 | 1 | 0 | [
"Eukaryota",
"Viruses"
] | [
139,
1481
] | 2 | [
"Arabidopsis thaliana"
] | [
5
] | 1 | true | Family | Nucleocapsid, Phlebovirus/Tenuivirus | Nucleocapsid, Phlebovirus/Tenuivirus | Capsid_Phlebovir/Tenuivir | 8 |
IPR009523 | 9,523 | Prokineticin | Prokineticin | Family | 1,622 | false | false | The prokineticin family includes prokinectin itself and related proteins such as BM8 and the AVIToxins. The suprachiasmatic nucleus (SCN) controls the circadian rhythm of physiological and behavioural processes in mammals. It has been shown that prokineticin 2 (PK2), a cysteine-rich secreted protein, functions as an ou... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR18821"
] | [
""
] | [
1622
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-HSA-375276",
"R-HSA-416476",
"R-MMU-375276",
"R-MMU-416476",
"R-RNO-375276",
"R-RNO-416476"
] | [
"REACTOME:R-HSA-375276",
"REACTOME:R-HSA-416476",
"REACTOME:R-MMU-375276",
"REACTOME:R-MMU-416476",
"REACTOME:R-RNO-375276",
"REACTOME:R-RNO-416476"
] | 6 | [
"1imt",
"2kra"
] | 2 | [
"PUB00012756"
] | [
"12024206"
] | [
"Prokineticin 2 transmits the behavioural circadian rhythm of the suprachiasmatic nucleus."
] | [
2002
] | 1 | [] | [] | 0 | 0 | null | [
"Bilateria"
] | [
1622
] | 1 | [
"Danio rerio",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
5,
2,
3,
10
] | 4 | true | Family | Prokineticin | Prokineticin | Prokineticin | 9 |
IPR009524 | 9,524 | Cilia- and flagella-associated protein 68 | CFAP68 | Family | 671 | false | false | This family consists of cilia- and flagella-associated protein 68 from animals, a microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating [ ]. | [
"GO:0030317",
"GO:0005634"
] | [
"flagellated sperm motility",
"nucleus"
] | [
"biological_process",
"cellular_component"
] | 2 | [
"PFAM"
] | [
"PF06608"
] | [
"CFAP68"
] | [
671
] | 1 | [] | [] | [] | 0 | [
"7ung",
"8iyj",
"8j07",
"8otz",
"8snb",
"9fqr"
] | 6 | [
"PUB00103594"
] | [
"36191189"
] | [
"SPACA9 is a lumenal protein of human ciliary singlet and doublet microtubules."
] | [
2022
] | 1 | [
"IPR037662"
] | [] | 1 | 0 | 1 | [
"Metazoa"
] | [
671
] | 1 | [
"Danio rerio",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
1,
5,
3,
5
] | 4 | true | Family | Cilia- and flagella-associated protein 68 | Cilia- and flagella-associated protein 68 | CFAP68 | 3 |
IPR009525 | 9,525 | Protein of unknown function DUF1145 | DUF1145 | Family | 2,472 | false | false | This entry consists of several hypothetical bacterial proteins of unknown function. | [] | [] | [] | 0 | [
"PFAM",
"PANTHER"
] | [
"PF06611",
"PTHR38775"
] | [
"DUF1145",
""
] | [
2467,
2348
] | 2 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"metagenomes"
] | [
2468,
4
] | 2 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Protein of unknown function DUF1145 | Protein of unknown function DUF1145 | DUF1145 | 2 |
IPR009526 | 9,526 | Protein of unknown function DUF1146 | DUF1146 | Family | 2,749 | false | false | Members of this protein family are small, typically about 80 residues in length, and are highly hydrophobic. The gene is found so far only in a subset of the firmicutes in association with genes of the ATP synthase F1 complex or NADH-quinone oxidoreductase. This family includes YwzB from Bacillus subtilis. | [] | [] | [] | 0 | [
"PFAM",
"NCBIFAM"
] | [
"PF06612",
"TIGR02327"
] | [
"DUF1146",
"int_mem_ywzB"
] | [
2749,
2338
] | 2 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"metagenomes"
] | [
2744,
5
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function DUF1146 | Protein of unknown function DUF1146 | DUF1146 | 1 |
IPR009527 | 9,527 | Circovirus 2, Orf1 | Circovirus2_Orf1 | Family | 8 | false | false | This family consists of Circovirus 2 ORF1 (also known as Protein NS0), which may be involved in host modulation [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06615"
] | [
"Circovir2_Orf1"
] | [
8
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00097766"
] | [
"12954212"
] | [
"The essential and nonessential transcription units for viral protein synthesis and DNA replication of porcine circovirus type 2."
] | [
2003
] | 1 | [] | [] | 0 | 0 | null | [
"Porcine circovirus 2"
] | [
8
] | 1 | [] | [] | 0 | true | Family | Circovirus 2, Orf1 | Circovirus 2, Orf1 | Circovirus2_Orf1 | 1 |
IPR009528 | 9,528 | BsuBI/PstI restriction endonuclease domain | Restrct_endonuc_II_BsuBI_C | Domain | 935 | false | false | There are four classes of restriction endonucleases: types I, II, III and IV. All types of enzymes recognise specific short DNA sequences and carry out the endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates. They differ in their recognition sequence, subunit compositi... | [
"GO:0000287",
"GO:0003677",
"GO:0009036",
"GO:0009307"
] | [
"magnesium ion binding",
"DNA binding",
"type II site-specific deoxyribonuclease activity",
"DNA restriction-modification system"
] | [
"molecular_function",
"molecular_function",
"molecular_function",
"biological_process"
] | 4 | [
"PFAM"
] | [
"PF06616"
] | [
"BsuBI_PstI_RE"
] | [
935
] | 1 | [
"EC"
] | [
"3.1.21.4"
] | [
"EC:3.1.21.4"
] | 1 | [
"2ixs"
] | 1 | [
"PUB00012760",
"PUB00035691",
"PUB00035692",
"PUB00035693",
"PUB00035694",
"PUB00035705",
"PUB00035707"
] | [
"1480472",
"15770420",
"14576294",
"11827971",
"11557805",
"15121719",
"12665693"
] | [
"BsuBI--an isospecific restriction and modification system of PstI: characterization of the BsuBI genes and enzymes.",
"Type II restriction endonucleases: structure and mechanism.",
"Diversity of type II restriction endonucleases that require two DNA recognition sites.",
"Evolutionary relationship between dif... | [
1992,
2005,
2003,
2002,
2001,
2004,
2003
] | 7 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Methanobacteriota",
"Viruses",
"metagenomes"
] | [
884,
4,
12,
16,
19
] | 5 | [] | [] | 0 | true | Domain | BsuBI/PstI restriction endonuclease domain | BsuBI/PstI restriction endonuclease domain | Restrct_endonuc_II_BsuBI_C | 2 |
IPR009529 | 9,529 | Maize streak virus, 13.1kDa | Maize_streak_virus_13.1kDa | Family | 3 | false | false | This family consists of several Maize streak virus proteins of unknown function. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06618"
] | [
"DUF1148"
] | [
3
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Maize streak virus"
] | [
3
] | 1 | [] | [] | 0 | true | Family | Maize streak virus, 13.1kDa | Maize streak virus, 13.1kDa | Maize_streak_virus_13.1kDa | 2 |
IPR009530 | 9,530 | Protein of unknown function DUF1149 | DUF1149 | Family | 784 | false | false | This entry consists of several hypothetical bacterial proteins of unknown function. | [] | [] | [] | 0 | [
"PFAM",
"PIRSF"
] | [
"PF06619",
"PIRSF031568"
] | [
"DUF1149",
"UCP031568"
] | [
784,
754
] | 2 | [] | [] | [] | 0 | [
"2hng",
"2o2a"
] | 2 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"bioreactor metagenome"
] | [
783,
1
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function DUF1149 | Protein of unknown function DUF1149 | DUF1149 | 9 |
IPR009531 | 9,531 | Protein of unknown function DUF1150 | DUF1150 | Family | 2,191 | false | false | This entry consists of several hypothetical bacterial proteins of unknown function. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06620"
] | [
"DUF1150"
] | [
2191
] | 1 | [] | [] | [] | 0 | [
"9jwa"
] | 1 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"metagenomes"
] | [
2175,
16
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function DUF1150 | Protein of unknown function DUF1150 | DUF1150 | 6 |
IPR009532 | 9,532 | SepQ/SsaQ, N-terminal domain | SepQ/SsaQ_N | Domain | 859 | false | false | This entry represents the N-terminal domain of several enterobacterial SepQ/SsaQ proteins. The function of this domain is unclear. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06622"
] | [
"SepQ"
] | [
859
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Pseudomonadota"
] | [
859
] | 1 | [] | [] | 0 | true | Domain | SepQ/SsaQ, N-terminal domain | SepQ/SsaQ, N-terminal domain | SepQ/SsaQ_N | 9 |
IPR009533 | 9,533 | FAM107 | FAM107 | Family | 3,616 | false | false | This entry includes FAM107A/B. FAM107A (also known as DRR1) is an actin-associated protein that plays important roles in tumor cell growth, neuron survival and spine formation [ ]. The function of FAM107B is not clear. | [] | [] | [] | 0 | [
"PFAM",
"PANTHER"
] | [
"PF06625",
"PTHR16768"
] | [
"DUF1151",
""
] | [
3614,
3530
] | 2 | [] | [] | [] | 0 | [] | 0 | [
"PUB00090183"
] | [
"28604741"
] | [
"A novel nuclear complex of DRR1, F-actin and COMMD1 involved in NF-κB degradation and cell growth suppression in neuroblastoma."
] | [
2017
] | 1 | [] | [] | 0 | 0 | null | [
"Metazoa"
] | [
3616
] | 1 | [
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
19,
2,
16,
9,
13
] | 5 | true | Family | FAM107 | FAM107 | FAM107 | 2 |
IPR009534 | 9,534 | Protein of unknown function DUF1153 | DUF1153 | Family | 2,859 | false | false | This family consists of several short, hypothetical bacterial proteins of unknown function. | [] | [] | [] | 0 | [
"NCBIFAM",
"PFAM"
] | [
"NF051866",
"PF06627"
] | [
"CtrAInhibSciP",
"DUF1153"
] | [
2435,
2859
] | 2 | [] | [] | [] | 0 | [
"2jrt",
"2oa4"
] | 2 | [
"PUB00162958"
] | [
"22790399"
] | [
"The Caulobacter crescentus ctrA P1 promoter is essential for the coordination of cell cycle events that prevent the overinitiation of DNA replication."
] | [
2012
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"metagenomes"
] | [
2839,
2,
18
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF1153 | Protein of unknown function DUF1153 | DUF1153 | 7 |
IPR009536 | 9,536 | Cucumber mosaic virus, OrfIIB | CucumberMosaicV_OrfIIB | Family | 5 | false | false | This family consists of several Cucumber mosaic virus ORF IIB proteins. The function of this family is unknown. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06633"
] | [
"DUF1155"
] | [
5
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Cucumber mosaic virus"
] | [
5
] | 1 | [] | [] | 0 | true | Family | Cucumber mosaic virus, OrfIIB | Cucumber mosaic virus, OrfIIB | CucumberMosaicV_OrfIIB | 5 |
IPR009537 | 9,537 | Domain of unknown function DUF1156 | DUF1156 | Domain | 1,717 | false | false | This entry represents a conserved region within hypothetical prokaryotic and archaeal proteins of unknown function. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06634"
] | [
"DUF1156"
] | [
1717
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"metagenomes"
] | [
295,
1387,
35
] | 3 | [] | [] | 0 | true | Domain | Domain of unknown function DUF1156 | Domain of unknown function DUF1156 | DUF1156 | 2 |
IPR009539 | 9,539 | Vang-like protein | VANGL | Family | 3,286 | false | false | VANGL proteins play important roles in the establishment of planar cell polarity (PCP) [ ]. Vangl2 is required for retinal axon guidance [ ], kidney-branching morphogenesis and glomerular maturation [ ]. It also plays a role in the orientation of stereociliary bundles in the cochlea and is required for polarization and... | [
"GO:0007275",
"GO:0016020"
] | [
"multicellular organism development",
"membrane"
] | [
"biological_process",
"cellular_component"
] | 2 | [
"PFAM",
"PIRSF",
"PANTHER"
] | [
"PF06638",
"PIRSF007991",
"PTHR20886"
] | [
"Strabismus",
"Strabismus",
""
] | [
3269,
2329,
3255
] | 3 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOM... | [
"R-DRE-9696264",
"R-DRE-9696270",
"R-DRE-9696273",
"R-HSA-4086400",
"R-HSA-4608870",
"R-HSA-8980692",
"R-HSA-9013026",
"R-HSA-9013106",
"R-HSA-9013148",
"R-HSA-9013149",
"R-HSA-9013404",
"R-HSA-9013405",
"R-HSA-9013406",
"R-HSA-9013407",
"R-HSA-9013408",
"R-HSA-9013409",
"R-HSA-90134... | [
"REACTOME:R-DRE-9696264",
"REACTOME:R-DRE-9696270",
"REACTOME:R-DRE-9696273",
"REACTOME:R-HSA-4086400",
"REACTOME:R-HSA-4608870",
"REACTOME:R-HSA-8980692",
"REACTOME:R-HSA-9013026",
"REACTOME:R-HSA-9013106",
"REACTOME:R-HSA-9013148",
"REACTOME:R-HSA-9013149",
"REACTOME:R-HSA-9013404",
"REACTOM... | 44 | [
"8zxd",
"9jk6",
"9jk7",
"9jk8",
"9jk9",
"9jka"
] | 6 | [
"PUB00077141",
"PUB00077142",
"PUB00077143",
"PUB00077144",
"PUB00077145"
] | [
"24981109",
"25990804",
"20843830",
"15637299",
"16495441"
] | [
"Vangl1 and Vangl2: planar cell polarity components with a developing role in cancer.",
"The planar cell polarity protein vangl2 is required for retinal axon guidance.",
"The planar cell polarity gene Vangl2 is required for mammalian kidney-branching morphogenesis and glomerular maturation.",
"Vangl2 acts via... | [
2014,
2015,
2010,
2005,
2006
] | 5 | [] | [] | 0 | 0 | null | [
"Metazoa"
] | [
3286
] | 1 | [
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
2,
9,
4,
4,
11,
6
] | 6 | true | Family | Vang-like protein | Vang-like protein | VANGL | 9 |
IPR009540 | 9,540 | Basal layer antifungal peptide | BAP | Family | 262 | false | false | This family consists of several basal layer antifungal peptide (BAP) sequences mainly from maize, wheat and sorghum. The BAP2 peptide exhibits potent broad-range activity against a range of filamentous fungi, including several plant pathogens [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06639"
] | [
"BAP"
] | [
262
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00012770"
] | [
"11319035"
] | [
"Maize endosperm secretes a novel antifungal protein into adjacent maternal tissue."
] | [
2001
] | 1 | [] | [] | 0 | 0 | null | [
"Mesangiospermae"
] | [
262
] | 1 | [
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
8,
32
] | 2 | true | Family | Basal layer antifungal peptide | Basal layer antifungal peptide | BAP | 6 |
IPR009542 | 9,542 | Signal peptidase complex subunit 1 | Spc1/SPCS1 | Family | 5,246 | false | false | Translocation of polypeptide chains across the endoplasmic reticulum (ER) membrane is triggered by signal sequences. Subsequently, signal recognition particle interacts with its membrane receptor and the ribosome-bound nascent chain is targeted to the ER where it is transferred into a protein-conducting channel. At som... | [
"GO:0006465",
"GO:0005787",
"GO:0016020"
] | [
"signal peptide processing",
"signal peptidase complex",
"membrane"
] | [
"biological_process",
"cellular_component",
"cellular_component"
] | 3 | [
"PFAM",
"PANTHER"
] | [
"PF06645",
"PTHR13202"
] | [
"SPC12",
""
] | [
5239,
4607
] | 2 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-CFA-422085",
"R-CFA-9768727",
"R-DME-9768727",
"R-HSA-1799339",
"R-HSA-381771",
"R-HSA-400511",
"R-HSA-422085",
"R-HSA-9768727",
"R-HSA-9828806",
"R-MMU-422085",
"R-MMU-9768727"
] | [
"REACTOME:R-CFA-422085",
"REACTOME:R-CFA-9768727",
"REACTOME:R-DME-9768727",
"REACTOME:R-HSA-1799339",
"REACTOME:R-HSA-381771",
"REACTOME:R-HSA-400511",
"REACTOME:R-HSA-422085",
"REACTOME:R-HSA-9768727",
"REACTOME:R-HSA-9828806",
"REACTOME:R-MMU-422085",
"REACTOME:R-MMU-9768727"
] | 11 | [
"6wve",
"7p2p",
"7p2q"
] | 3 | [
"PUB00010061",
"PUB00087521",
"PUB00090357",
"PUB00094327",
"PUB00094328",
"PUB00094329",
"PUB00094330",
"PUB00094332"
] | [
"8632014",
"8663399",
"22111585",
"27383988",
"24009510",
"29593046",
"8910564",
"23573290"
] | [
"Membrane topology of the 12- and the 25-kDa subunits of the mammalian signal peptidase complex.",
"The homologue of mammalian SPC12 is important for efficient signal peptidase activity in Saccharomyces cerevisiae.",
"The rice gene DEFECTIVE TAPETUM AND MEIOCYTES 1 (DTM1) is required for early tapetum developme... | [
1996,
1996,
2012,
2016,
2013,
2018,
1996,
2013
] | 8 | [] | [
"IPR039955"
] | 0 | 1 | 0 | [
"Bacteria",
"Eukaryota"
] | [
6,
5240
] | 2 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Saccharomyces cerevisiae (strai... | [
13,
1,
1,
2,
3,
4,
1,
5,
2,
1,
1,
13
] | 12 | true | Family | Signal peptidase complex subunit 1 | Signal peptidase complex subunit 1 | Spc1/SPCS1 | 4 |
IPR009543 | 9,543 | Vacuolar protein sorting-associated protein 13, VPS13 adaptor binding domain | VPS13_VAB | Domain | 13,337 | false | false | This entry represents the VPS13 adaptor binding (VAB) domain, previously known as SHR-BD, found in VPS13 [ , ]. This domain interacts with Ypt35 which recruits VPS13 to endosomal and vacuolar membranes, and with Mcp1 to target VPS13 at mitochondria [ ]. In plants, this domain is found to be the region which interacts w... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25036"
] | [
"VPS13_VAB"
] | [
13337
] | 1 | [] | [] | [] | 0 | [
"7u8t"
] | 1 | [
"PUB00016718",
"PUB00100501",
"PUB00100502",
"PUB00100726",
"PUB00100766",
"PUB00100768",
"PUB00100769",
"PUB00100863",
"PUB00101861",
"PUB00101953"
] | [
"11381253",
"30018089",
"23444357",
"34830155",
"30741634",
"30709847",
"30093493",
"34216812",
"35491307",
"35357422"
] | [
"A conserved sorting-associated protein is mutant in chorea-acanthocytosis.",
"Competitive organelle-specific adaptors recruit Vps13 to membrane contact sites.",
"Identification of SHRUBBY, a SHORT-ROOT and SCARECROW interacting protein that controls root growth and radial patterning.",
"The GTPase Arf1 Is a ... | [
2001,
2018,
2013,
2021,
2019,
2019,
2018,
2021,
2022,
2022
] | 10 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
13337
] | 1 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Saccharomyces cerevisiae (strai... | [
42,
6,
38,
2,
11,
13,
1,
5,
24,
1,
2,
44
] | 12 | true | Domain | Vacuolar protein sorting-associated protein 13, VPS13 adaptor binding domain | Vacuolar protein sorting-associated protein 13, VPS13 adaptor binding domain | VPS13_VAB | 5 |
IPR009544 | 9,544 | Protein of unknown function DUF1163 | DUF1163 | Family | 264 | false | false | This entry represents a group of hypothetical Arabidopsis thaliana proteins of unknown function. | [] | [] | [] | 0 | [
"PFAM",
"PIRSF",
"PANTHER"
] | [
"PF06651",
"PIRSF026169",
"PTHR31125"
] | [
"DUF1163",
"DUF1163",
""
] | [
244,
21,
249
] | 3 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Chryseobacterium oryzae",
"Mesangiospermae",
"Natrinema altunense"
] | [
1,
262,
1
] | 3 | [
"Arabidopsis thaliana"
] | [
29
] | 1 | true | Family | Protein of unknown function DUF1163 | Protein of unknown function DUF1163 | DUF1163 | 1 |
IPR009545 | 9,545 | Tight junction protein, claudin-like | Claudin-like | Family | 507 | false | false | This is a family of probable membrane tight junction, claudin-like, proteins. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06653"
] | [
"Claudin_3"
] | [
507
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
507
] | 1 | [
"Caenorhabditis elegans"
] | [
34
] | 1 | true | Family | Tight junction protein, claudin-like | Tight junction protein, claudin-like | Claudin-like | 3 |
IPR009547 | 9,547 | Tenuivirus PVC2 | Tenui_PVC2 | Family | 89 | false | false | This family consists of several Tenuivirus PVC2 proteins from Rice grassy stunt virus, Maize stripe virus and Rice hoja blanca virus. The function of this family is unknown. | [] | [] | [] | 0 | [
"PFAM",
"PIRSF"
] | [
"PF06656",
"PIRSF011360"
] | [
"Tenui_PVC2",
"Tenui_PVC2"
] | [
89,
74
] | 2 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Tenuivirus"
] | [
89
] | 1 | [] | [] | 0 | true | Family | Tenuivirus PVC2 | Tenuivirus PVC2 | Tenui_PVC2 | 2 |
IPR009548 | 9,548 | PRKR-interacting protein 1 | Prkrip1 | Family | 4,093 | false | false | Prkrip1, also known as protein C114, is a double-stranded RNA-binding protein [ ]. It consists of a fully extended N-terminal loop (residues 51-75) and an 18-turn α helix (residues 76-142). It directly links the catalytic centre with the U2 snRNP at the periphery of the spliceosome [ ]. | [
"GO:0003725"
] | [
"double-stranded RNA binding"
] | [
"molecular_function"
] | 1 | [
"PFAM",
"PANTHER"
] | [
"PF06658",
"PTHR13507"
] | [
"DUF1168",
""
] | [
4058,
3961
] | 2 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-CEL-72163",
"R-DRE-72163",
"R-HSA-72163",
"R-MMU-72163"
] | [
"REACTOME:R-CEL-72163",
"REACTOME:R-DRE-72163",
"REACTOME:R-HSA-72163",
"REACTOME:R-MMU-72163"
] | 4 | [
"5xjc",
"6icz",
"6qdv",
"7w5a",
"7w5b",
"8c6j",
"9fmd"
] | 7 | [
"PUB00092513",
"PUB00092514"
] | [
"12679338",
"28502770"
] | [
"C114 is a novel IL-11-inducible nuclear double-stranded RNA-binding protein that inhibits protein kinase R.",
"An Atomic Structure of the Human Spliceosome."
] | [
2003,
2017
] | 2 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota"
] | [
2,
4091
] | 2 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Zea mays"
] | [
3,
1,
2,
1,
2,
2,
1,
2,
3,
6
] | 10 | true | Family | PRKR-interacting protein 1 | PRKR-interacting protein 1 | Prkrip1 | 6 |
IPR009550 | 9,550 | VirE3 | VirE3 | Family | 103 | false | false | This family represents a conserved region within Agrobacterium tumefaciens VirE3. Agrobacterium tumefaciens (a plant pathogen) has a tumour-inducing (Ti) plasmid of which part, the transfer (T)-region, is transferred to plant cells during the infection process. Vir proteins mediate the processing of the T-region and th... | [] | [] | [] | 0 | [
"PFAM",
"PIRSF"
] | [
"PF06661",
"PIRSF036105"
] | [
"VirE3",
"VirE3"
] | [
103,
57
] | 2 | [] | [] | [] | 0 | [] | 0 | [
"PUB00012780"
] | [
"12560481"
] | [
"Analysis of Vir protein translocation from Agrobacterium tumefaciens using Saccharomyces cerevisiae as a model: evidence for transport of a novel effector protein VirE3."
] | [
2003
] | 1 | [] | [] | 0 | 0 | null | [
"Eukaryota",
"Hyphomicrobiales",
"Plasmid Ti"
] | [
10,
92,
1
] | 3 | [] | [] | 0 | true | Family | VirE3 | VirE3 | VirE3 | 9 |
IPR009551 | 9,551 | Protein wntless | Wntless | Family | 2,789 | false | false | Protein wntless (WLS) regulates Wnt proteins sorting and secretion in a feedback regulatory mechanism [ , , ]. This reciprocal interaction plays a key role in the regulation of expression, subcellular location, binding and organelle-specific association of Wnt proteins. It also plays also an important role in establish... | [
"GO:0017147",
"GO:0016055"
] | [
"Wnt-protein binding",
"Wnt signaling pathway"
] | [
"molecular_function",
"biological_process"
] | 2 | [
"PANTHER"
] | [
"PTHR13449"
] | [
""
] | [
2789
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-CEL-3238698",
"R-DME-3238698",
"R-HSA-3238698",
"R-MMU-3238698",
"R-RNO-3238698"
] | [
"REACTOME:R-CEL-3238698",
"REACTOME:R-DME-3238698",
"REACTOME:R-HSA-3238698",
"REACTOME:R-MMU-3238698",
"REACTOME:R-RNO-3238698"
] | 5 | [
"7drt",
"7kc4",
"8tzo",
"8tzp",
"8tzr",
"8tzs"
] | 6 | [
"PUB00061859",
"PUB00061860",
"PUB00061861",
"PUB00061862",
"PUB00151072"
] | [
"16678095",
"16678096",
"19841259",
"17108000",
"36373655"
] | [
"Wntless, a conserved membrane protein dedicated to the secretion of Wnt proteins from signaling cells.",
"Secretion of Wnt ligands requires Evi, a conserved transmembrane protein.",
"Reciprocal regulation of Wnt and Gpr177/mouse Wntless is required for embryonic axis formation.",
"Sprinter: a novel transmemb... | [
2006,
2006,
2009,
2006,
2022
] | 5 | [] | [] | 0 | 0 | null | [
"Metazoa"
] | [
2789
] | 1 | [
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
1,
2,
1,
12,
2,
5
] | 6 | true | Family | Protein wntless | Protein wntless | Wntless | 7 |
IPR009553 | 9,553 | Protein of unknown function DUF1173 | DUF1173 | Family | 1,255 | false | false | This family contains a group of hypothetical bacterial proteins that contain three conserved cysteine residues towards the N-terminal. The function of these proteins is unknown. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06666"
] | [
"DUF1173"
] | [
1255
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"ecological metagenomes"
] | [
1234,
13,
8
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF1173 | Protein of unknown function DUF1173 | DUF1173 | 9 |
IPR009554 | 9,554 | Phage shock protein B | Phageshock_PspB | Family | 2,621 | false | false | This family consists of several bacterial phage shock protein B (PspB) sequences, also known as envelope stress response membrane protein PspB. The phage shock protein (psp) operon is induced in response to heat, ethanol, osmotic shock and infection by filamentous bacteriophages [ ]. Expression of the operon requires t... | [
"GO:0006355",
"GO:0009271"
] | [
"regulation of DNA-templated transcription",
"phage shock"
] | [
"biological_process",
"biological_process"
] | 2 | [
"PFAM",
"NCBIFAM"
] | [
"PF06667",
"TIGR02976"
] | [
"PspB",
"phageshock_pspB"
] | [
2620,
2491
] | 2 | [
"GP"
] | [
"GenProp0648"
] | [
"GP:GenProp0648"
] | 1 | [] | 0 | [
"PUB00012784",
"PUB00012785",
"PUB00034603"
] | [
"1712397",
"12562786",
"16468999"
] | [
"Characterization and sequence of the Escherichia coli stress-induced psp operon.",
"Interactions between phage-shock proteins in Escherichia coli.",
"PspB and PspC of Yersinia enterocolitica are dual function proteins: regulators and effectors of the phage-shock-protein response."
] | [
1991,
2003,
2006
] | 3 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"unclassified sequences"
] | [
2607,
2,
12
] | 3 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Phage shock protein B | Phage shock protein B | Phageshock_PspB | 6 |
IPR009556 | 9,556 | Microneme Etmic-2 | Microneme_Etmic-2 | Family | 19 | false | false | This family consists of several Microneme protein Etmic-2 sequences from Eimeria tenella. Etmic-2 is a 50kDa acidic protein, which is found within the microneme organelles of E. tenella sporozoites and merozoites [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06670"
] | [
"Etmic-2"
] | [
19
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00012795"
] | [
"8855556"
] | [
"Molecular cloning and characterization of a novel acidic microneme protein (Etmic-2) from the apicomplexan protozoan parasite, Eimeria tenella."
] | [
1996
] | 1 | [] | [] | 0 | 0 | null | [
"Eimeriidae"
] | [
19
] | 1 | [] | [] | 0 | true | Family | Microneme Etmic-2 | Microneme Etmic-2 | Microneme_Etmic-2 | 9 |
IPR009557 | 9,557 | Repeat of unknown function DUF1174 | DUF1174 | Repeat | 31 | false | false | This entry consists of a number of Caenorhabditis elegans specific repeats of around 36 residues in length which are found in two hypothetical proteins. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06671"
] | [
"DUF1174"
] | [
31
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Caenorhabditis"
] | [
31
] | 1 | [
"Caenorhabditis elegans"
] | [
12
] | 1 | true | Repeat | Repeat of unknown function DUF1174 | Repeat of unknown function DUF1174 | DUF1174 | 8 |
IPR009558 | 9,558 | Protein of unknown function DUF1175 | DUF1175 | Family | 813 | false | false | This family consists of several hypothetical bacterial proteins of around 210 residues in length. The function of this family is unknown. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06672"
] | [
"DUF1175"
] | [
813
] | 1 | [] | [] | [] | 0 | [
"7bk8"
] | 1 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Darwinula stevensoni",
"human gut metagenome"
] | [
809,
1,
3
] | 3 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Protein of unknown function DUF1175 | Protein of unknown function DUF1175 | DUF1175 | 7 |
IPR009559 | 9,559 | Lactococcus phage c2, major capsid protein | Lactococcus_phage_c2_MCP | Family | 72 | false | false | This family consists of several Lactococcus lactis bacteriophage major capsid proteins. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06673"
] | [
"L_lactis_ph-MCP"
] | [
72
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacilli",
"Viruses"
] | [
5,
67
] | 2 | [] | [] | 0 | true | Family | Lactococcus phage c2, major capsid protein | Lactococcus phage c2, major capsid protein | Lactococcus_phage_c2_MCP | 7 |
IPR009560 | 9,560 | Protein of unknown function DUF1176 | DUF1176 | Family | 3,312 | false | false | This family consists of several hypothetical bacterial proteins of around 340 residues in length. Members of this family contain six highly conserved cysteine residues. The function of this family is unknown. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06674"
] | [
"DUF1176"
] | [
3312
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"metagenomes"
] | [
3295,
9,
8
] | 3 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Protein of unknown function DUF1176 | Protein of unknown function DUF1176 | DUF1176 | 8 |
IPR009561 | 9,561 | Protein of unknown function DUF1177 | DUF1177 | Family | 1,139 | false | false | This family consists of several hypothetical archaeal and bacterial proteins of around 300 residues in length. The function of this family is unknown. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06675"
] | [
"DUF1177"
] | [
1139
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Anopheles maculatus",
"Archaea",
"Bacteria",
"metagenomes"
] | [
1,
76,
1050,
12
] | 4 | [] | [] | 0 | true | Family | Protein of unknown function DUF1177 | Protein of unknown function DUF1177 | DUF1177 | 4 |
IPR009562 | 9,562 | Protein of unknown function DUF1178 | DUF1178 | Family | 3,892 | false | false | This family consists of several hypothetical bacterial proteins of around 150 residues in length. The function of this family is unknown. | [] | [] | [] | 0 | [
"PFAM",
"PIRSF"
] | [
"PF06676",
"PIRSF032131"
] | [
"DUF1178",
"UCP032131"
] | [
3892,
3676
] | 2 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"unclassified sequences"
] | [
3828,
7,
57
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF1178 | Protein of unknown function DUF1178 | DUF1178 | 5 |
IPR009563 | 9,563 | ZNRD2-like, N-terminal domain | ZNRD2_N | Domain | 2,655 | false | false | This entry represents a domain found at the N-terminal of ZNRD2. It is thought that the potential association of ZNRD2 with anti-centromere antibodies suggests that this protein might play a role in mitosis [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06677"
] | [
"Auto_anti-p27"
] | [
2655
] | 1 | [] | [] | [] | 0 | [
"6hcz"
] | 1 | [
"PUB00012796"
] | [
"9486406"
] | [
"cDNA cloning of a novel autoantigen targeted by a minor subset of anti-centromere antibodies."
] | [
1998
] | 1 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"ecological metagenomes"
] | [
817,
11,
1805,
22
] | 4 | [
"Caenorhabditis elegans",
"Danio rerio",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus",
"Schizosaccharomyces pombe (strain 972 / ATCC 24843)"
] | [
1,
1,
5,
6,
2,
1
] | 6 | true | Domain | ZNRD2-like, N-terminal domain | ZNRD2-like, N-terminal domain | ZNRD2_N | 4 |
IPR009564 | 9,564 | Protein of unknown function DUF1179 | DUF1179 | Family | 52 | false | false | This family consists of several hypothetical Caenorhabditis elegans proteins of around 106 residues in length. The function of the family is unknown. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06678"
] | [
"DUF1179"
] | [
52
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Rhabditomorpha"
] | [
52
] | 1 | [
"Caenorhabditis elegans"
] | [
9
] | 1 | true | Family | Protein of unknown function DUF1179 | Protein of unknown function DUF1179 | DUF1179 | 8 |
IPR009565 | 9,565 | Membrane protein FAM174-like | FAM174-like | Family | 1,869 | false | false | This entry represents a group of animal membrane proteins, including human Membrane protein FAM174B, which is essential for Golgi structural integrity [ ]. | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR28607"
] | [
""
] | [
1869
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00151893"
] | [
"29851555"
] | [
"Targeted protein unfolding uncovers a Golgi-specific transcriptional stress response."
] | [
2018
] | 1 | [] | [] | 0 | 0 | null | [
"Eumetazoa"
] | [
1869
] | 1 | [
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
3,
3,
3,
5,
9
] | 5 | true | Family | Membrane protein FAM174-like | Membrane protein FAM174-like | FAM174-like | 8 |
IPR009566 | 9,566 | Protein of unknown function DUF1181 | DUF1181 | Family | 15 | false | false | This family consists of several hypothetical proteins of around 120 residues in length which are found specifically in Trypanosoma brucei. The function of this family is unknown. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06680"
] | [
"DUF1181"
] | [
15
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Trypanosoma brucei"
] | [
15
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF1181 | Protein of unknown function DUF1181 | DUF1181 | 2 |
IPR009567 | 9,567 | Store-operated calcium entry-associated regulatory factor | SARAF | Family | 3,052 | false | false | SARAF is an endoplasmic reticulum membrane resident protein that serves as a negative regulator of store-operated Ca2+ entry (SOCE) involved in protecting cells from Ca2+ overfilling. It is a single pass ER membrane protein whose systolic-facing domain is responsible for activity and whose luminary-facing domain carrie... | [
"GO:2001256",
"GO:0005789"
] | [
"regulation of store-operated calcium entry",
"endoplasmic reticulum membrane"
] | [
"biological_process",
"cellular_component"
] | 2 | [
"PFAM",
"PANTHER"
] | [
"PF06682",
"PTHR15929"
] | [
"SARAF",
""
] | [
3051,
2970
] | 2 | [] | [] | [] | 0 | [
"6o2u",
"6o2v",
"6o2w"
] | 3 | [
"PUB00075537"
] | [
"22464749"
] | [
"SARAF inactivates the store operated calcium entry machinery to prevent excess calcium refilling."
] | [
2012
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Viruses",
"viral metagenome"
] | [
2,
3042,
7,
1
] | 4 | [
"Caenorhabditis elegans",
"Danio rerio",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Rattus norvegicus"
] | [
1,
3,
9,
2,
1,
5
] | 6 | true | Family | Store-operated calcium entry-associated regulatory factor | Store-operated calcium entry-associated regulatory factor | SARAF | 3 |
IPR009568 | 9,568 | Protein of unknown function DUF1184 | DUF1184 | Family | 303 | false | false | This family contains a number of hypothetical proteins of unknown function from Arabidopsis thaliana. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06683"
] | [
"DUF1184"
] | [
303
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [
"IPR016970"
] | 0 | 1 | 0 | [
"Brassicaceae"
] | [
303
] | 1 | [
"Arabidopsis thaliana"
] | [
28
] | 1 | true | Family | Protein of unknown function DUF1184 | Protein of unknown function DUF1184 | DUF1184 | 2 |
IPR009569 | 9,569 | Amino acid synthesis, putative | AA_synth_put | Family | 3,847 | false | false | This family of proteins is structurally similar to proteins with the Bacillus chorismate mutase-like (BCM-like) fold. This structure, combined with its genomic context, suggest that it has a role in amino acid synthesis [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06684"
] | [
"AA_synth"
] | [
3847
] | 1 | [] | [] | [] | 0 | [
"2qtp",
"3byq"
] | 2 | [
"PUB00057508"
] | [
"20944209"
] | [
"Structures of the first representatives of Pfam family PF06684 (DUF1185) reveal a novel variant of the Bacillus chorismate mutase fold and suggest a role in amino-acid metabolism."
] | [
2010
] | 1 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"unclassified sequences"
] | [
5,
3754,
6,
82
] | 4 | [] | [] | 0 | true | Family | Amino acid synthesis, putative | Amino acid synthesis, putative | AA_synth_put | 3 |
IPR009570 | 9,570 | Stage III sporulation protein AC | Spore_III_AC | Family | 2,280 | false | false | This family consists of several bacterial stage III sporulation protein AC (SpoIIIAC) sequences. The exact function of this family is unknown. | [] | [] | [] | 0 | [
"NCBIFAM"
] | [
"TIGR02848"
] | [
"spore_III_AC"
] | [
2280
] | 1 | [
"GP"
] | [
"GenProp0610"
] | [
"GP:GenProp0610"
] | 1 | [] | 0 | [] | [] | [] | [] | 0 | [
"IPR025664"
] | [] | 1 | 0 | 1 | [
"Bacteria",
"metagenomes"
] | [
2262,
18
] | 2 | [] | [] | 0 | true | Family | Stage III sporulation protein AC | Stage III sporulation protein AC | Spore_III_AC | 3 |
IPR009571 | 9,571 | Membrane protein SUR7/Rim9-like, fungi | SUR7/Rim9-like_fungi | Family | 9,713 | false | false | This entry consists of several fungal-specific membrane proteins, including Sur7 and Rim9. This entry also includes PalI which is part of a pH signal transduction cascade. Based on the similarity of PalI to the yeast Rim9 meiotic signal transduction component it has been suggested that PalI might be a membrane sensor f... | [
"GO:0005886"
] | [
"plasma membrane"
] | [
"cellular_component"
] | 1 | [
"PFAM"
] | [
"PF06687"
] | [
"SUR7"
] | [
9713
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00012798",
"PUB00035442",
"PUB00075473"
] | [
"11784867",
"9791171",
"25228775"
] | [
"The Sur7p family defines novel cortical domains in Saccharomyces cerevisiae, affects sphingolipid metabolism, and is involved in sporulation.",
"Putative membrane components of signal transduction pathways for ambient pH regulation in Aspergillus and meiosis in saccharomyces are homologous.",
"Identification o... | [
2002,
1998,
2014
] | 3 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
9713
] | 1 | [
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)",
"Schizosaccharomyces pombe (strain 972 / ATCC 24843)"
] | [
6,
10,
3
] | 3 | true | Family | Membrane protein SUR7/Rim9-like, fungi | Membrane protein SUR7/Rim9-like, fungi | SUR7/Rim9-like_fungi | 6 |
IPR009572 | 9,572 | Protein of unknown function DUF1187 | DUF1187 | Family | 458 | false | false | This family consists of several short, hypothetical bacterial proteins of around 62 residues in length. Members of this family are found in Escherichia coli and Salmonella typhi. The function of this family is unknown. | [] | [] | [] | 0 | [
"NCBIFAM",
"PFAM"
] | [
"NF007283",
"PF06688"
] | [
"PRK09750.1",
"DUF1187"
] | [
304,
458
] | 2 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Callosobruchus maculatus",
"Podoviridae sp. ct3k57"
] | [
456,
1,
1
] | 3 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Protein of unknown function DUF1187 | Protein of unknown function DUF1187 | DUF1187 | 2 |
IPR009573 | 9,573 | FeGP cofactor biosynthesis protein, methyltransferase HcgC | HcgC | Family | 79 | false | false | The iron guanylylpyridinol (FeGP) cofactor biosynthesis enzymes are encoded in a cluster of at least seven conserved genes (hcgA-G). This family represents the (SAM)-dependent methyltransferase HgcC [ , ], which covalently attaches the methyl group at the 3-position of the pyridinol ring. It is predominantly found as a... | [] | [] | [] | 0 | [
"PFAM",
"PIRSF"
] | [
"PF06690",
"PIRSF019265"
] | [
"HcgC",
"DUF1188"
] | [
79,
26
] | 2 | [] | [] | [] | 0 | [
"5d4t",
"5d4u",
"5d4v",
"5d5o",
"5d5t",
"5o4h",
"5o4j",
"5o4m",
"5o4n"
] | 9 | [
"PUB00098592",
"PUB00098593"
] | [
"28682478",
"27391308"
] | [
"A Water-Bridged H-Bonding Network Contributes to the Catalysis of the SAM-Dependent C-Methyltransferase HcgC.",
"Identification of HcgC as a SAM-Dependent Pyridinol Methyltransferase in [Fe]-Hydrogenase Cofactor Biosynthesis."
] | [
2017,
2016
] | 2 | [] | [] | 0 | 0 | null | [
"Desulfurobacterium",
"Methanobacteriota",
"bioreactor metagenome"
] | [
4,
74,
1
] | 3 | [] | [] | 0 | true | Family | FeGP cofactor biosynthesis protein, methyltransferase HcgC | FeGP cofactor biosynthesis protein, methyltransferase HcgC | HcgC | 2 |
IPR009574 | 9,574 | Protein of unknown function DUF1189 | DUF1189 | Family | 2,135 | false | false | This family is predominantly composed of bacterial proteins. Their function is unknown, although one family member, , has been suggested to have a role in maltodextrin utilisation [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06691"
] | [
"DUF1189"
] | [
2135
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00067851"
] | [
"16707683"
] | [
"Maltose and maltodextrin utilization by Bacillus subtilis."
] | [
2006
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Trichuris trichiura",
"ecological metagenomes"
] | [
2130,
1,
4
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF1189 | Protein of unknown function DUF1189 | DUF1189 | 4 |
IPR009575 | 9,575 | Melon necrotic spot virus P7B | MNSV_P7B | Family | 36 | false | false | This family consists of several Melon necrotic spot virus (MNSV) P7B proteins. The function of this family is unknown. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06692"
] | [
"MNSV_P7B"
] | [
36
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Procedovirinae",
"Streptomyces anulatus"
] | [
35,
1
] | 2 | [] | [] | 0 | true | Family | Melon necrotic spot virus P7B | Melon necrotic spot virus P7B | MNSV_P7B | 8 |
IPR009576 | 9,576 | Biofilm formation YgiB | Biofilm_formation_YgiB | Family | 3,753 | false | false | The proteins in this entry, which include YgiB, are functionally uncharacterised, however, transcription of ygiB is induced upon biofilm formation compared to planktonic growth in both exponential and stationary phase. Induction of expression was found to be dependent on the presence of the F plasmid [ ]. Biofilm forma... | [] | [] | [] | 0 | [
"HAMAP",
"PFAM"
] | [
"MF_01188",
"PF06693"
] | [
"UPF0441",
"DUF1190"
] | [
956,
3753
] | 2 | [] | [] | [] | 0 | [] | 0 | [
"PUB00053950"
] | [
"14731270"
] | [
"Global impact of mature biofilm lifestyle on Escherichia coli K-12 gene expression."
] | [
2004
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Caudoviricetes",
"Eukaryota",
"unclassified sequences"
] | [
3669,
65,
5,
14
] | 4 | [
"Escherichia coli (strain K12)"
] | [
2
] | 1 | true | Family | Biofilm formation YgiB | Biofilm formation YgiB | Biofilm_formation_YgiB | 8 |
IPR009577 | 9,577 | Putative small multi-drug export | Sm_multidrug_ex | Family | 3,604 | false | false | This family contains a small number of putative small multi-drug export proteins. | [] | [] | [] | 0 | [
"PFAM",
"PANTHER"
] | [
"PF06695",
"PTHR36007"
] | [
"Sm_multidrug_ex",
""
] | [
3554,
2332
] | 2 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"metagenomes",
"unclassified Caudoviricetes"
] | [
434,
2404,
674,
90,
2
] | 5 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
6,
3,
10
] | 3 | true | Family | Putative small multi-drug export | Putative small multi-drug export | Sm_multidrug_ex | 6 |
IPR009579 | 9,579 | Protein of unknown function DUF1192 | DUF1192 | Family | 1,814 | false | false | This family consists of several short, hypothetical, bacterial proteins of around 60 residues in length. The function of this family is unknown. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06698"
] | [
"DUF1192"
] | [
1814
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Halovenus salina",
"Symbiodinium microadriaticum",
"ecological metagenomes"
] | [
1794,
1,
1,
18
] | 4 | [] | [] | 0 | true | Family | Protein of unknown function DUF1192 | Protein of unknown function DUF1192 | DUF1192 | 7 |
IPR009580 | 9,580 | GPI biosynthesis protein Pig-F | GPI_biosynthesis_protein_Pig-F | Family | 3,934 | false | false | Glycosylphosphatidylinositol anchor biosynthesis protein Pig-F is involved in glycosylphosphatidylinositol (GPI) anchor biosynthesis [ , , ]. This family also includes the Pif-F homologue GPI11 (glycosylphosphatidylinositol anchor biosynthesis protein 11) [ ]. It is involved in the ethanolamine-phosphate transfer-step ... | [
"GO:0006506",
"GO:0005789"
] | [
"GPI anchor biosynthetic process",
"endoplasmic reticulum membrane"
] | [
"biological_process",
"cellular_component"
] | 2 | [
"PFAM"
] | [
"PF06699"
] | [
"PIG-F"
] | [
3934
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-HSA-162710",
"R-MMU-162710",
"R-SCE-162710",
"R-SPO-1660661"
] | [
"REACTOME:R-HSA-162710",
"REACTOME:R-MMU-162710",
"REACTOME:R-SCE-162710",
"REACTOME:R-SPO-1660661"
] | 4 | [] | 0 | [
"PUB00013429",
"PUB00020117",
"PUB00020118",
"PUB00059223",
"PUB00089757"
] | [
"12655644",
"11995915",
"10781593",
"10793139",
"25074286"
] | [
"Enzymes and auxiliary factors for GPI lipid anchor biosynthesis and post-translational transfer to proteins.",
"Glycosylphosphatidylinositol (GPI)-anchored proteins.",
"Requirement of PIG-F and PIG-O for transferring phosphoethanolamine to the third mannose in glycosylphosphatidylinositol.",
"Glycosylphospha... | [
2003,
2002,
2000,
2000,
2014
] | 5 | [] | [] | 0 | 0 | null | [
"Chromohalobacter israelensis (strain ATCC BAA-138 / DSM 3043 / CIP 106854 / NCIMB 13768 / 1H11)",
"Eukaryota"
] | [
1,
3933
] | 2 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Saccharomyces cerevisiae (strai... | [
10,
1,
1,
2,
4,
3,
1,
6,
5,
1,
1,
16
] | 12 | true | Family | GPI biosynthesis protein Pig-F | GPI biosynthesis protein Pig-F | GPI_biosynthesis_protein_Pig-F | 7 |
IPR009581 | 9,581 | FAM20, C-terminal | FAM20_C | Domain | 5,784 | false | false | This entry represents the C-terminal of the eukaryotic secreted Golgi casein kinase protein FAM20C. FAM20C is the Golgi casein kinase that phosphorylates secretory pathway proteins within Ser-x-Glu/pSer motifs. Mutations in the FAM20C gene cause Raine syndrome, an autosomal recessive osteosclerotic bone dysplasia [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06702"
] | [
"Fam20C"
] | [
5784
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-CEL-381426",
"R-CEL-8957275",
"R-DME-1971475",
"R-DME-381426",
"R-DME-8957275",
"R-DRE-1971475",
"R-HSA-1971475",
"R-HSA-381426",
"R-HSA-8957275",
"R-MMU-1971475",
"R-MMU-381426",
"R-MMU-8957275"
] | [
"REACTOME:R-CEL-381426",
"REACTOME:R-CEL-8957275",
"REACTOME:R-DME-1971475",
"REACTOME:R-DME-381426",
"REACTOME:R-DME-8957275",
"REACTOME:R-DRE-1971475",
"REACTOME:R-HSA-1971475",
"REACTOME:R-HSA-381426",
"REACTOME:R-HSA-8957275",
"REACTOME:R-MMU-1971475",
"REACTOME:R-MMU-381426",
"REACTOME:R-... | 12 | [
"4kqa",
"4kqb",
"5wrr",
"5wrs",
"5xom",
"5xoo",
"5yh0",
"5yh2",
"5yh3"
] | 9 | [
"PUB00075539"
] | [
"23754375"
] | [
"Crystal structure of the Golgi casein kinase."
] | [
2013
] | 1 | [] | [] | 0 | 0 | null | [
"Eukaryota",
"Sandaracinus amylolyticus"
] | [
5782,
2
] | 2 | [
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
1,
14,
3,
7,
3,
8
] | 6 | true | Domain | FAM20, C-terminal | FAM20, C-terminal | FAM20_C | 1 |
IPR009582 | 9,582 | Signal peptidase complex subunit 2 | Spc2/SPCS2 | Family | 4,838 | false | false | This family represents the Signal peptidase complex subunit 2 (SPCS2) and its homologues, such as Spc2 from budding yeasts. The signal peptidase complex cleaves the signal sequence from proteins targeted to the endoplasmic reticulum (ER). Mammalian signal peptidase is as a complex of five different polypeptide chains [... | [
"GO:0006465",
"GO:0005787",
"GO:0016020"
] | [
"signal peptide processing",
"signal peptidase complex",
"membrane"
] | [
"biological_process",
"cellular_component",
"cellular_component"
] | 3 | [
"PFAM",
"PANTHER"
] | [
"PF06703",
"PTHR13085"
] | [
"SPC25",
""
] | [
4815,
4575
] | 2 | [
"GP",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"GenProp2038",
"R-CFA-422085",
"R-CFA-9768727",
"R-DME-9768727",
"R-DRE-422085",
"R-DRE-9768727",
"R-HSA-1799339",
"R-HSA-381771",
"R-HSA-400511",
"R-HSA-422085",
"R-HSA-9768727",
"R-HSA-9828806",
"R-MMU-422085",
"R-MMU-9768727"
] | [
"GP:GenProp2038",
"REACTOME:R-CFA-422085",
"REACTOME:R-CFA-9768727",
"REACTOME:R-DME-9768727",
"REACTOME:R-DRE-422085",
"REACTOME:R-DRE-9768727",
"REACTOME:R-HSA-1799339",
"REACTOME:R-HSA-381771",
"REACTOME:R-HSA-400511",
"REACTOME:R-HSA-422085",
"REACTOME:R-HSA-9768727",
"REACTOME:R-HSA-98288... | 14 | [
"7p2p",
"7p2q"
] | 2 | [
"PUB00010061",
"PUB00087521",
"PUB00094330",
"PUB00094331"
] | [
"8632014",
"8663399",
"8910564",
"10921929"
] | [
"Membrane topology of the 12- and the 25-kDa subunits of the mammalian signal peptidase complex.",
"The homologue of mammalian SPC12 is important for efficient signal peptidase activity in Saccharomyces cerevisiae.",
"Structurally related Spc1p and Spc2p of yeast signal peptidase complex are functionally distin... | [
1996,
1996,
1996,
2000
] | 4 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota"
] | [
5,
4833
] | 2 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Saccharomyces cerevisiae (strai... | [
11,
1,
1,
4,
6,
6,
1,
4,
2,
1,
1,
9
] | 12 | true | Family | Signal peptidase complex subunit 2 | Signal peptidase complex subunit 2 | Spc2/SPCS2 | 5 |
IPR009584 | 9,584 | Citrus tristeza virus 6kDa protein | CTV_6kDa | Family | 23 | false | false | This family consists of several Citrus tristeza virus (CTV) 6kDa, 51 residue long hydrophobic (P6) proteins. The function of this family is unknown. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06706"
] | [
"CTV_P6"
] | [
23
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Closterovirus"
] | [
23
] | 1 | [] | [] | 0 | true | Family | Citrus tristeza virus 6kDa protein | Citrus tristeza virus 6kDa protein | CTV_6kDa | 3 |
IPR009587 | 9,587 | Protein of unknown function DUF1198 | DUF1198 | Family | 987 | false | false | This family consists of several bacterial proteins of around 150 residues in length which are specific to Escherichia coli, Salmonella species and Yersinia pestis. The function of this family is unknown. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06711"
] | [
"DUF1198"
] | [
987
] | 1 | [] | [] | [] | 0 | [
"5tf3"
] | 1 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Pseudomonadota",
"Trichuris trichiura",
"metagenomes"
] | [
984,
1,
2
] | 3 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Protein of unknown function DUF1198 | Protein of unknown function DUF1198 | DUF1198 | 7 |
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