interpro_id string | interpro_numeric_id int64 | name string | short_name string | entry_type string | protein_count int64 | is_llm bool | is_llm_reviewed bool | abstract string | go_ids list | go_terms list | go_categories list | go_count int64 | member_databases list | member_accessions list | member_names list | member_protein_counts list | member_count int64 | external_databases list | external_accessions list | external_xrefs list | external_xref_count int64 | pdb_ids list | structure_count int64 | publication_ids list | pubmed_ids list | publication_titles list | publication_years list | publication_count int64 | parent_ids list | child_ids list | parent_count int64 | child_count int64 | tree_depth float64 | taxonomy_names list | taxonomy_protein_counts list | taxonomy_count int64 | key_species_names list | key_species_protein_counts list | key_species_count int64 | in_entry_list bool | entry_list_type string | entry_list_name string | names_dat_name string | short_names_dat_name string | split_bucket int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
IPR009717 | 9,717 | Mo-dependent nitrogenase, C-terminal | Mo-dep_Nase_C | Domain | 1,138 | false | false | This entry represents the C terminus (approximately 80 residues) of a number of bacterial Mo-dependent nitrogenases. These are involved in nitrogen fixation in cyanobacteria [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06967"
] | [
"Mo-nitro_C"
] | [
1138
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00012953"
] | [
"7568132"
] | [
"A second nitrogenase in vegetative cells of a heterocyst-forming cyanobacterium."
] | [
1995
] | 1 | [] | [] | 0 | 0 | null | [
"Cyanobacteriota",
"Cyanophage S-TIM5"
] | [
1137,
1
] | 2 | [] | [] | 0 | true | Domain | Mo-dependent nitrogenase, C-terminal | Mo-dependent nitrogenase, C-terminal | Mo-dep_Nase_C | 2 |
IPR009718 | 9,718 | Rex DNA-binding, C-terminal domain | Rex_DNA-bd_C_dom | Domain | 9,027 | false | false | This entry represents the C terminus (approximately 30 residues) of a number of Rex proteins. These are redox-sensing repressors that appear to be widespread among Gram-positive bacteria [ ]. They modulate transcription in response to changes in cellular NADH/NAD (+) redox state. Rex is predicted to include a pyridine ... | [
"GO:0045892",
"GO:0051775"
] | [
"negative regulation of DNA-templated transcription",
"response to redox state"
] | [
"biological_process",
"biological_process"
] | 2 | [
"PFAM"
] | [
"PF06971"
] | [
"Put_DNA-bind_N"
] | [
9027
] | 1 | [] | [] | [] | 0 | [
"1xcb",
"2dt5",
"2vt2",
"2vt3",
"3ikt",
"3ikv",
"3il2",
"3keo",
"3keq",
"3ket",
"3wg9",
"3wgg",
"3wgh",
"3wgi",
"5zz5",
"5zz6",
"5zz7",
"7wb3"
] | 18 | [
"PUB00015140"
] | [
"12970197"
] | [
"A novel sensor of NADH/NAD+ redox poise in Streptomyces coelicolor A3(2)."
] | [
2003
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"unclassified sequences"
] | [
8814,
10,
203
] | 3 | [] | [] | 0 | true | Domain | Rex DNA-binding, C-terminal domain | Rex DNA-binding, C-terminal domain | Rex_DNA-bd_C_dom | 4 |
IPR009719 | 9,719 | GBF-interacting protein 1, N-terminal | GIP1_N | Domain | 4,080 | false | false | This entry represents the N-terminal domain of GBF1-interacting protein 1 (GIP1, AT3G13222) from Arabidopsis. GIP1 may act as a coactivator that regulates transcription factors involved in lateral organ development of plants, such as bZIP transcription factors and LBD18 [ , ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06972"
] | [
"GIP1_N"
] | [
4080
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00074653",
"PUB00074654"
] | [
"24484953",
"25387999"
] | [
"GIP1 may act as a coactivator that enhances transcriptional activity of LBD18 in Arabidopsis.",
"GIP1 protein is a novel cofactor that regulates DNA-binding affinity of redox-regulated members of bZIP transcription factors involved in the early stages of Arabidopsis development."
] | [
2014,
2015
] | 2 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
4080
] | 1 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
38,
14,
86
] | 3 | true | Domain | GBF-interacting protein 1, N-terminal | GBF-interacting protein 1, N-terminal | GIP1_N | 2 |
IPR009720 | 9,720 | IMP biosynthesis enzyme PurP, C-terminal | IMP_biosynth_PurP_C | Domain | 1,003 | false | false | This entry represents the C-terminal domain of PurP, which is homologous to the ATP-GRASP fold and thus may be involved in ATP-binding. It is almost always found in association with . The last two steps of de novo purine biosynthesis are: conversion of 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosph... | [
"GO:0000287",
"GO:0005524",
"GO:0016879",
"GO:0006188"
] | [
"magnesium ion binding",
"ATP binding",
"ligase activity, forming carbon-nitrogen bonds",
"IMP biosynthetic process"
] | [
"molecular_function",
"molecular_function",
"molecular_function",
"biological_process"
] | 4 | [
"PFAM"
] | [
"PF06973"
] | [
"DUF1297"
] | [
1003
] | 1 | [
"EC",
"METACYC"
] | [
"6.3.4.23",
"PWY-7234"
] | [
"EC:6.3.4.23",
"METACYC:PWY-7234"
] | 2 | [
"2pbz",
"2r7k",
"2r7l",
"2r7m",
"2r7n",
"2r84",
"2r85",
"2r86",
"2r87"
] | 9 | [
"PUB00013793",
"PUB00025174",
"PUB00034499",
"PUB00034500"
] | [
"11844782",
"11323713",
"9150241",
"15623504"
] | [
"New class of IMP cyclohydrolases in Methanococcus jannaschii.",
"Crystal structure of a bifunctional transformylase and cyclohydrolase enzyme in purine biosynthesis.",
"Purine biosynthesis in the domain Archaea without folates or modified folates.",
"A Methanocaldococcus jannaschii archaeal signature gene en... | [
2002,
2001,
1997,
2005
] | 4 | [
"IPR011761"
] | [] | 1 | 0 | 1 | [
"Archaea",
"Bacteria",
"ecological metagenomes"
] | [
823,
130,
50
] | 3 | [] | [] | 0 | true | Domain | IMP biosynthesis enzyme PurP, C-terminal | IMP biosynthesis enzyme PurP, C-terminal | IMP_biosynth_PurP_C | 6 |
IPR009721 | 9,721 | O-acyltransferase WSD1, C-terminal | O-acyltransferase_WSD1_C | Domain | 19,505 | false | false | This entry represents the C terminus (approximately 170 residues) of wax ester synthase/diacylglycerol acyltransferases (WS/DGATs), predominantly from bacteria and plants, including O-acyltransferase WSD1 which is involved in cuticular wax biosynthesis [ ]. They catalyse the condensation of a fatty alcohol and a fatty ... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06974"
] | [
"WS_DGAT_C"
] | [
19505
] | 1 | [
"EC"
] | [
"2.3.1.20"
] | [
"EC:2.3.1.20"
] | 1 | [
"6chj",
"7nxg"
] | 2 | [
"PUB00053680",
"PUB00100087"
] | [
"18621978",
"31559109"
] | [
"Identification of the wax ester synthase/acyl-coenzyme A: diacylglycerol acyltransferase WSD1 required for stem wax ester biosynthesis in Arabidopsis.",
"Structural and Biochemical Studies of a Biocatalyst for the Enzymatic Production of Wax Esters."
] | [
2008,
2018
] | 2 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Stenosarchaea group",
"metagenomes"
] | [
12256,
7111,
6,
132
] | 4 | [
"Arabidopsis thaliana",
"Drosophila melanogaster",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
67,
1,
13,
5
] | 4 | true | Domain | O-acyltransferase WSD1, C-terminal | O-acyltransferase WSD1, C-terminal | O-acyltransferase_WSD1_C | 1 |
IPR009722 | 9,722 | YjiK/CarP | YjiK/CarP | Family | 4,990 | false | false | This entry represents a family of hypothetical bacterial proteins that may be regulated by SdiA, a member of the LuxR family of transcriptional regulators [ ]. This entry includes the uncharacterised protein YjiK in Escherichia coli and the calcium-regulated β-propeller protein CarP in Pseudomonas, which plays a role i... | [] | [] | [] | 0 | [
"PFAM",
"CDD"
] | [
"PF06977",
"cd09971"
] | [
"SdiA-regulated",
"SdiA-regulated"
] | [
4990,
3423
] | 2 | [] | [] | [] | 0 | [
"3qqz"
] | 1 | [
"PUB00012958",
"PUB00153158",
"PUB00161094"
] | [
"9495757",
"33674436",
"26755627"
] | [
"Salmonella typhimurium encodes an SdiA homolog, a putative quorum sensor of the LuxR family, that regulates genes on the virulence plasmid.",
"Calcium-Regulated Protein CarP Responds to Multiple Host Signals and Mediates Regulation of Pseudomonas aeruginosa Virulence by Calcium.",
"The Pseudomonas aeruginosa P... | [
1998,
2021,
2016
] | 3 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"metagenomes"
] | [
4878,
87,
25
] | 3 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | YjiK/CarP | YjiK/CarP | YjiK/CarP | 1 |
IPR009724 | 9,724 | TMEM70 family | TMEM70 | Family | 2,569 | false | false | TMEM70 is a family of proteins essential for assembly of the mitochondrial proton-transporting ATP synthase complex within the inner mitochondrial membrane [ , , ]. | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR13281"
] | [
""
] | [
2569
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00075430",
"PUB00075431",
"PUB00075432"
] | [
"18953340",
"20937241",
"22986587"
] | [
"TMEM70 mutations cause isolated ATP synthase deficiency and neonatal mitochondrial encephalocardiomyopathy.",
"Expression and processing of the TMEM70 protein.",
"TMEM70: a mutational hot spot in nuclear ATP synthase deficiency with a pivotal role in complex V biogenesis."
] | [
2008,
2011,
2012
] | 3 | [
"IPR045325"
] | [] | 1 | 0 | 1 | [
"Eukaryota"
] | [
2569
] | 1 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Schizosaccharomyces pombe (strain 972 / ATCC 24843)",
"Zea mays"
] | [
3,
2,
1,
1,
3,
2,
5,
4,
1,
4
] | 10 | true | Family | TMEM70 family | TMEM70 family | TMEM70 | 3 |
IPR009725 | 9,725 | Predicted 3-demethylubiquinone-9 3-methyltransferase | 3_dmu_93_MTrfase | Family | 10,235 | false | false | This entry contains a number of predicted bacterial and archaeal 3-demethylubiquinone-9 3-methyltransferases, which have a conserved region of approximately 100 residues. In some proteins this region occurs more than once. | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF021700"
] | [
"3_dmu_93_MTrfase"
] | [
10235
] | 1 | [] | [] | [] | 0 | [
"1tsj",
"1u69",
"1u7i",
"3oms"
] | 4 | [] | [] | [] | [] | 0 | [] | [
"IPR027259"
] | 0 | 1 | 0 | [
"Archaea",
"Bacteria",
"Eukaryota",
"metagenomes"
] | [
44,
9790,
329,
72
] | 4 | [] | [] | 0 | true | Family | Predicted 3-demethylubiquinone-9 3-methyltransferase | Predicted 3-demethylubiquinone-9 3-methyltransferase | 3_dmu_93_MTrfase | 6 |
IPR009727 | 9,727 | NifT/FixU | NifT | Family | 1,181 | false | false | This family consists of several NifT and FixU bacterial proteins. The function of NifT is unknown although it is thought that the protein may be involved in biosynthesis of the FeMo cofactor of nitrogenase although perturbation of nifT expression in Klebsiella pneumoniae has only a limited effect on nitrogen fixation [... | [
"GO:0009399"
] | [
"nitrogen fixation"
] | [
"biological_process"
] | 1 | [
"PFAM",
"NCBIFAM"
] | [
"PF06988",
"TIGR02934"
] | [
"NifT",
"nifT_nitrog"
] | [
1181,
1171
] | 2 | [
"GP"
] | [
"GenProp0029"
] | [
"GP:GenProp0029"
] | 1 | [
"2jn4"
] | 1 | [
"PUB00006373"
] | [
"9139910"
] | [
"Identification and characterization of the nifV-nifZ-nifT gene region from the filamentous cyanobacterium Anabaena sp. strain PCC 7120."
] | [
1997
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria",
"metagenomes"
] | [
1166,
15
] | 2 | [] | [] | 0 | true | Family | NifT/FixU | NifT/FixU | NifT | 6 |
IPR009728 | 9,728 | BAALC | BAALC | Family | 1,109 | false | false | This entry represents the mammalian BAALC proteins. BAALC (brain and acute leukaemia, cytoplasmic) is highly conserved among mammals, but is absent from lower organisms. Two isoforms are specifically expressed in neuroectoderm-derived tissues, but not in tumours or cancer cell lines of non-neural tissue origin. It has ... | [
"GO:0005737"
] | [
"cytoplasm"
] | [
"cellular_component"
] | 1 | [
"PFAM",
"PANTHER"
] | [
"PF06989",
"PTHR14731"
] | [
"BAALC_N",
""
] | [
886,
1096
] | 2 | [] | [] | [] | 0 | [] | 0 | [
"PUB00012963"
] | [
"11707601"
] | [
"BAALC, the human member of a novel mammalian neuroectoderm gene lineage, is implicated in hematopoiesis and acute leukemia."
] | [
2001
] | 1 | [] | [] | 0 | 0 | null | [
"Vertebrata"
] | [
1109
] | 1 | [
"Danio rerio",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
4,
1,
2,
3
] | 4 | true | Family | BAALC | BAALC | BAALC | 7 |
IPR009729 | 9,729 | Galactose-3-O-sulfotransferase | Gal-3-0_sulfotransfrase | Family | 6,525 | false | false | This family consists of several animal galactose-3-O-sulphotransferases, including GAL3ST1-4. GAL3ST1 (also known as Cst, cerebroside sulfotransferase) is responsible for the biosynthesis of two types of sulfoglycolipids, sulfatide (HSO3-3-galactosylceramide) and seminolipid (HSO3-3-monogalactosylalkylacylglycerol), in... | [
"GO:0001733",
"GO:0009247",
"GO:0016020"
] | [
"galactosylceramide sulfotransferase activity",
"glycolipid biosynthetic process",
"membrane"
] | [
"molecular_function",
"biological_process",
"cellular_component"
] | 3 | [
"PFAM",
"PANTHER"
] | [
"PF06990",
"PTHR14647"
] | [
"Gal-3-0_sulfotr",
""
] | [
6375,
6360
] | 2 | [
"EC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"REACTOME",
"REACTOME"
] | [
"2.8.2.-",
"PWY-6546",
"PWY-6558",
"PWY-6567",
"PWY-6568",
"PWY-7831",
"PWY-8045",
"PWY-8358",
"PWY-8381",
"R-HSA-9840309",
"R-MMU-9840309"
] | [
"EC:2.8.2.-",
"METACYC:PWY-6546",
"METACYC:PWY-6558",
"METACYC:PWY-6567",
"METACYC:PWY-6568",
"METACYC:PWY-7831",
"METACYC:PWY-8045",
"METACYC:PWY-8358",
"METACYC:PWY-8381",
"REACTOME:R-HSA-9840309",
"REACTOME:R-MMU-9840309"
] | 11 | [] | 0 | [
"PUB00076962"
] | [
"11917099"
] | [
"Paranodal junction formation and spermatogenesis require sulfoglycolipids."
] | [
2002
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"metagenomes"
] | [
84,
6437,
4
] | 3 | [
"Danio rerio",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
14,
27,
12,
9
] | 4 | true | Family | Galactose-3-O-sulfotransferase | Galactose-3-O-sulfotransferase | Gal-3-0_sulfotransfrase | 7 |
IPR009730 | 9,730 | Micro-fibrillar-associated protein 1, C-terminal | MFAP1_C | Domain | 4,506 | false | false | This entry represents the C terminus (approximately 300 residues) of eukaryotic micro-fibrillar-associated protein 1, which is a component of elastin-associated microfibrils in the extracellular matrix [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06991"
] | [
"MFAP1"
] | [
4506
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-BTA-72163",
"R-HSA-72163",
"R-MMU-72163"
] | [
"REACTOME:R-BTA-72163",
"REACTOME:R-HSA-72163",
"REACTOME:R-MMU-72163"
] | 3 | [
"5f5s",
"5f5t",
"5f5u",
"5f5v",
"5o9z",
"6ahd",
"7aav",
"7abf",
"7abg",
"7abi",
"8h6k",
"8q7n",
"8qo9",
"8qpe",
"8qzs"
] | 15 | [
"PUB00012965"
] | [
"8174780"
] | [
"Conversion to an elastogenic phenotype by fetal hyaline chondrocytes is accompanied by altered expression of elastin-related macromolecules."
] | [
1994
] | 1 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
4506
] | 1 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Schizosaccharomyces pombe (stra... | [
6,
1,
1,
1,
1,
2,
1,
11,
2,
1,
2
] | 11 | true | Domain | Micro-fibrillar-associated protein 1, C-terminal | Micro-fibrillar-associated protein 1, C-terminal | MFAP1_C | 7 |
IPR009731 | 9,731 | Replication P-like | P-like | Family | 2,203 | false | false | This entry represents a family of proteins from tailed bacteriophages and proteobacterial prophages, including Bacteriophage lambda replication protein P, also known as Helicase loader. This protein promotes replication of the phage chromosome by recruiting a key component of the cellular replication machinery to the v... | [
"GO:0006270"
] | [
"DNA replication initiation"
] | [
"biological_process"
] | 1 | [
"PFAM"
] | [
"PF06992"
] | [
"Phage_lambda_P"
] | [
2203
] | 1 | [] | [] | [] | 0 | [
"6bbm",
"8v9s",
"9oa1",
"9oa2"
] | 4 | [
"PUB00012966",
"PUB00154482"
] | [
"2165499",
"30582519"
] | [
"Host virus interactions in the initiation of bacteriophage lambda DNA replication. Recruitment of Escherichia coli DnaB helicase by lambda P replication protein.",
"Mechanisms of opening and closing of the bacterial replicative helicase."
] | [
1990,
2018
] | 2 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Opisthokonta",
"Viruses",
"metagenomes"
] | [
2120,
6,
67,
10
] | 4 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Replication P-like | Replication P-like | P-like | 9 |
IPR009732 | 9,732 | Protein of unknown function DUF1304 | DUF1304 | Family | 7,418 | false | false | This family consists of several hypothetical bacterial proteins of around 120 residues in length. The function of this family is unknown. | [] | [] | [] | 0 | [
"PFAM",
"PANTHER"
] | [
"PF06993",
"PTHR38446"
] | [
"DUF1304",
""
] | [
7415,
6714
] | 2 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Methanobrevibacter gottschalkii",
"metagenomes"
] | [
7010,
377,
2,
29
] | 4 | [] | [] | 0 | true | Family | Protein of unknown function DUF1304 | Protein of unknown function DUF1304 | DUF1304 | 1 |
IPR009734 | 9,734 | Myoviridae, GpU | Myoviridae_GpU | Family | 5,542 | false | false | This family consists of several bacterial and phage proteins of around 130 residues in length which seem to be related to the bacteriophage P2 GpU protein ( ) which is thought to be involved in tail assembly [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF06995"
] | [
"Phage_P2_GpU"
] | [
5542
] | 1 | [] | [] | [] | 0 | [
"6u5b"
] | 1 | [
"PUB00012968"
] | [
"12426340"
] | [
"Programmed translational frameshift in the bacteriophage P2 FETUD tail gene operon."
] | [
2002
] | 1 | [] | [
"IPR014458",
"IPR016912"
] | 0 | 2 | 0 | [
"Bacteria",
"Eukaryota",
"Viruses",
"metagenomes"
] | [
5324,
9,
196,
13
] | 4 | [] | [] | 0 | true | Family | Myoviridae, GpU | Myoviridae, GpU | Myoviridae_GpU | 5 |
IPR009736 | 9,736 | Protein of unknown function DUF1307 | DUF1307 | Family | 1,814 | false | false | This family consists of several hypothetical bacterial proteins of around 150 residues in length. Some family members are described as putative lipoproteins but the function of the family is unknown. | [] | [] | [] | 0 | [
"PFAM",
"PIRSF"
] | [
"PF06998",
"PIRSF006187"
] | [
"DUF1307",
"DUF1307"
] | [
1814,
1338
] | 2 | [] | [] | [] | 0 | [
"2joe"
] | 1 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"human gut metagenome"
] | [
1811,
3
] | 2 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Protein of unknown function DUF1307 | Protein of unknown function DUF1307 | DUF1307 | 6 |
IPR009737 | 9,737 | Thioredoxin-like ferredoxin | Aim32/Apd1-like | Family | 8,398 | false | false | This entry includes proteins from fungi, plants and bacteria. Proteins in this entry contain a ferredoxin-like fold. They are predicted ferredoxins, which are iron-sulfur (Fe-S) proteins that may play a role in redox sensing and electron transfer [ ]. Some members appear to have sucrolytic activity [ ]. The putative ac... | [] | [] | [] | 0 | [
"PFAM",
"PANTHER",
"CDD"
] | [
"PF06999",
"PTHR31902",
"cd03062"
] | [
"Suc_Fer-like",
"",
"TRX_Fd_Sucrase"
] | [
8211,
6476,
6868
] | 3 | [] | [] | [] | 0 | [] | 0 | [
"PUB00012969",
"PUB00033323",
"PUB00078077"
] | [
"7957893",
"10628851",
"25600293"
] | [
"Characterisation of a complementary DNA encoding a novel plant enzyme with sucrolytic activity.",
"Functional analysis of 150 deletion mutants in Saccharomyces cerevisiae by a systematic approach.",
"Loss of APD1 in yeast confers hydroxyurea sensitivity suppressed by Yap1p transcription factor."
] | [
1994,
1999,
2015
] | 3 | [] | [
"IPR010350"
] | 0 | 1 | 0 | [
"Bacteria",
"Eukaryota",
"Methanolacinia petrolearia (strain DSM 11571 / OCM 486 / SEBR 4847)",
"unclassified sequences"
] | [
2971,
5375,
1,
51
] | 4 | [
"Arabidopsis thaliana",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)",
"Zea mays"
] | [
26,
2,
3,
2,
12
] | 5 | true | Family | Thioredoxin-like ferredoxin | Thioredoxin-like ferredoxin | Aim32/Apd1-like | 7 |
IPR009738 | 9,738 | BAT2, N-terminal | BAT2_N | Domain | 5,571 | false | false | This entry represents the N terminus (approximately 200 residues) of the proline-rich protein BAT2 (also known as PRRC2A). BAT2 is similar to other proteins with large proline-rich domains, such as some nuclear proteins, collagens, elastin, and synapsin [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF07001"
] | [
"BAT2_N"
] | [
5571
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00012970"
] | [
"2156268"
] | [
"A gene pair from the human major histocompatibility complex encodes large proline-rich proteins with multiple repeated motifs and a single ubiquitin-like domain."
] | [
1990
] | 1 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
5571
] | 1 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Zea mays"
] | [
8,
1,
20,
2,
21,
12,
2,
14,
8
] | 9 | true | Domain | BAT2, N-terminal | BAT2, N-terminal | BAT2_N | 3 |
IPR009739 | 9,739 | Lysozyme inhibitor LprI-like, N-terminal | LprI-like_N | Domain | 14,539 | false | false | This domain is found in uncharacterised bacterial proteins and towards the N-terminal part of lipoprotein LprI from Mycobacterium. The function of this domain is not known. LprI binds to and inhibits macrophage lysozyme, which may aid bacterial survival [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF07007"
] | [
"LprI"
] | [
14539
] | 1 | [] | [] | [] | 0 | [
"3gi7",
"6ar7"
] | 2 | [
"PUB00083126"
] | [
"26589796"
] | [
"Lipoprotein LprI of Mycobacterium tuberculosis Acts as a Lysozyme Inhibitor."
] | [
2016
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Viruses",
"metagenomes"
] | [
14442,
12,
30,
55
] | 4 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Domain | Lysozyme inhibitor LprI-like, N-terminal | Lysozyme inhibitor LprI-like, N-terminal | LprI-like_N | 7 |
IPR009741 | 9,741 | Protein EARLY FLOWERING 4 domain | EARLY_FLOWERING_4_dom | Domain | 2,463 | false | false | Protein EARLY FLOWERING 4 is a component of the central CCA1/LHY-TOC1 feedback loop in the circadian clock that promotes clock accuracy and is required for sustained rhythms in the absence of daily light/dark cycles [ , ]. This domain forms an α-helical homodimer in ELF4 proteins. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF07011"
] | [
"Elf4"
] | [
2463
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00084336",
"PUB00084337"
] | [
"12214234",
"20357892"
] | [
"The ELF4 gene controls circadian rhythms and flowering time in Arabidopsis thaliana.",
"Integrating ELF4 into the circadian system through combined structural and functional studies."
] | [
2002,
2009
] | 2 | [] | [] | 0 | 0 | null | [
"Viridiplantae"
] | [
2463
] | 1 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
18,
10,
13
] | 3 | true | Domain | Protein EARLY FLOWERING 4 domain | Protein EARLY FLOWERING 4 domain | EARLY_FLOWERING_4_dom | 2 |
IPR009742 | 9,742 | Curlin associated | Curlin_rpt | Repeat | 4,897 | false | false | This entry represents a bacterial repeated motif of around 30 residues in length. These repeats are often found in multiple copies in the curlin proteins CsgA and CsgB. Curli fibres are thin aggregative surface fibres, connected with adhesion, which bind laminin, fibronectin, plasminogen, human contact phase proteins, ... | [
"GO:0007155",
"GO:0009289"
] | [
"cell adhesion",
"pilus"
] | [
"biological_process",
"cellular_component"
] | 2 | [
"PFAM"
] | [
"PF07012"
] | [
"Curlin_rpt"
] | [
4897
] | 1 | [
"REACTOME"
] | [
"R-HSA-9638630"
] | [
"REACTOME:R-HSA-9638630"
] | 1 | [
"8c50",
"8enq",
"8enr"
] | 3 | [
"PUB00012975"
] | [
"11254632"
] | [
"Curli fibers mediate internalization of Escherichia coli by eukaryotic cells."
] | [
2001
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Halobacteriales",
"Opisthokonta",
"ecological metagenomes",
"uncultured Caudovirales phage"
] | [
4867,
6,
5,
13,
6
] | 5 | [
"Escherichia coli (strain K12)"
] | [
3
] | 1 | true | Repeat | Curlin associated | Curlin associated | Curlin_rpt | 3 |
IPR009744 | 9,744 | VirC1 | VirC1 | Family | 1,778 | false | false | This family consists of several bacterial VirC1 proteins. In Agrobacterium tumefaciens, a cis-active 24-base-pair sequence adjacent to the right border of the T-DNA, called overdrive, stimulates tumour formation by increasing the level of T-DNA processing. It is thought that the virC operon, which enhances T-DNA proces... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF07015"
] | [
"VirC1"
] | [
1778
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00012977"
] | [
"2592351"
] | [
"The Agrobacterium tumefaciens virC1 gene product binds to overdrive, a T-DNA transfer enhancer."
] | [
1989
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Viruses",
"ecological metagenomes"
] | [
1762,
4,
2,
10
] | 4 | [] | [] | 0 | true | Family | VirC1 | VirC1 | VirC1 | 2 |
IPR009745 | 9,745 | Cysteine-rich, acidic integral membrane | CRAM_rpt | Repeat | 14 | false | false | This entry represents a 24 residue repeated motif from the Trypanosoma brucei cysteine-rich, acidic integral membrane protein precursor (CRAM). CRAM is concentrated in the flagellar pocket, an invagination of the cell surface of the trypanosome where endocytosis has been documented [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF07016"
] | [
"CRAM_rpt"
] | [
14
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00012978"
] | [
"1697030"
] | [
"Characterization of a cDNA encoding a cysteine-rich cell surface protein located in the flagellar pocket of the protozoan Trypanosoma brucei."
] | [
1990
] | 1 | [] | [] | 0 | 0 | null | [
"Eukaryota",
"Haloarcula rubripromontorii",
"Pseudomonadati"
] | [
8,
1,
5
] | 3 | [] | [] | 0 | true | Repeat | Cysteine-rich, acidic integral membrane | Cysteine-rich, acidic integral membrane | CRAM_rpt | 8 |
IPR009746 | 9,746 | Llipid A acylation PagP | LipidA_acyl_PagP | Family | 1,951 | false | false | This family consists of several bacterial lipid A acylation (PagP) proteins. The bacterial outer membrane enzyme PagP transfers a palmitate chain from a phospholipid to lipid A. In a number of pathogenic Gram-negative bacteria, PagP confers resistance to certain cationic antimicrobial peptides produced during the host ... | [] | [] | [] | 0 | [
"HAMAP",
"PFAM"
] | [
"MF_00837",
"PF07017"
] | [
"PagP_transferase",
"PagP"
] | [
1569,
1951
] | 2 | [
"EC"
] | [
"2.3.1.251"
] | [
"EC:2.3.1.251"
] | 1 | [
"1mm4",
"1mm5",
"1thq",
"3gp6"
] | 4 | [
"PUB00060660"
] | [
"11013210"
] | [
"Transfer of palmitate from phospholipids to lipid A in outer membranes of gram-negative bacteria."
] | [
2000
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Caudoviricetes",
"Opisthokonta",
"metagenomes"
] | [
1923,
3,
6,
19
] | 4 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Llipid A acylation PagP | Llipid A acylation PagP | LipidA_acyl_PagP | 3 |
IPR009748 | 9,748 | Orthopoxvirus C10L | Orthopox_C10L | Family | 63 | false | false | This family consists of several Orthopoxvirus C10L proteins. C10L viral protein, also known as OPG024 protein, can play an important role in vaccinia virus evasion of the host immune system. It may consist in the blockade of IL-1 receptors by the C10L protein, a homologue of the IL-1 Ra [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF07020"
] | [
"Orthopox_C10L"
] | [
63
] | 1 | [] | [] | [] | 0 | [
"7nuf"
] | 1 | [
"PUB00012982"
] | [
"12084512"
] | [
"The immunosuppressive activity of peptide fragments of vaccinia virus C10L protein and a hypothesis on the role of this protein in the viral invasion."
] | [
2002
] | 1 | [] | [] | 0 | 0 | null | [
"Chordopoxvirinae",
"Punica granatum"
] | [
62,
1
] | 2 | [] | [] | 0 | true | Family | Orthopoxvirus C10L | Orthopoxvirus C10L | Orthopox_C10L | 4 |
IPR009749 | 9,749 | Protein of unknown function DUF1315 | DUF1315 | Family | 3,419 | false | false | This family consists of several bacterial proteins of around 90 residues in length. The function of this family is unknown. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF07023"
] | [
"DUF1315"
] | [
3419
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"metagenomes"
] | [
3405,
5,
9
] | 3 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Protein of unknown function DUF1315 | Protein of unknown function DUF1315 | DUF1315 | 6 |
IPR009750 | 9,750 | Protein of unknown function DUF1317 | DUF1317 | Family | 396 | false | false | This family consists of several hypothetical bacterial and phage proteins. The function of this family is unknown. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF07026"
] | [
"DUF1317"
] | [
396
] | 1 | [
"GP"
] | [
"GenProp0208"
] | [
"GP:GenProp0208"
] | 1 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Caudoviricetes",
"Daphnia magna"
] | [
353,
42,
1
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF1317 | Protein of unknown function DUF1317 | DUF1317 | 6 |
IPR009751 | 9,751 | CryBP1 | CryBP1 | Family | 69 | false | false | This family consists of several CryBP1-like proteins from Bacillus and Paenibacillus species, including Bacillus thuringiensis and Paenibacillus popilliae. Members of this family are thought to be involved in the overall toxicity of the bacteria to their hosts [ , ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF07029"
] | [
"CryBP1"
] | [
69
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00013438",
"PUB00013439"
] | [
"7730255",
"9209052"
] | [
"Transcriptional regulation of the cryIVD gene operon from Bacillus thuringiensis subsp. israelensis.",
"Cloning and analysis of the first cry gene from Bacillus popilliae."
] | [
1995,
1997
] | 2 | [] | [] | 0 | 0 | null | [
"Bacillota"
] | [
69
] | 1 | [] | [] | 0 | true | Family | CryBP1 | CryBP1 | CryBP1 | 8 |
IPR009752 | 9,752 | Bacteriophage Mu, Gene product J | Phage_Mu_GpJ | Family | 2,656 | false | false | This entry represents the Gene product J from Escherichia phage Mu (GpJ, previously known as Gp36) and similar proteins found in tailed bacteriophages and in bacterial prophages. The structure of GpJ shows a characteristic aromatic hydrophobic core. This protein might interact directly with the Head-tail connector (Gp2... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF07030"
] | [
"Phage_Mu_Gp36"
] | [
2656
] | 1 | [
"GP"
] | [
"GenProp0208"
] | [
"GP:GenProp0208"
] | 1 | [
"5ydn",
"8rka",
"8rkb",
"8rqe",
"9khx",
"9knu"
] | 6 | [
"PUB00099987"
] | [
"29767456"
] | [
"Three-dimensional structures of bacteriophage neck subunits are shared in Podoviridae, Siphoviridae and Myoviridae."
] | [
2018
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Viruses",
"unclassified sequences"
] | [
2430,
9,
150,
67
] | 4 | [] | [] | 0 | true | Family | Bacteriophage Mu, Gene product J | Bacteriophage Mu, Gene product J | Phage_Mu_GpJ | 4 |
IPR009753 | 9,753 | Protein of unknown function DUF1322 | DUF1322 | Family | 148 | false | false | This entry represents a family of hypothetical Borrelia proteins of around 78 residues in length. The function of this family is unknown. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF07032"
] | [
"DUF1322"
] | [
148
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria"
] | [
148
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF1322 | Protein of unknown function DUF1322 | DUF1322 | 9 |
IPR009754 | 9,754 | Orthopoxvirus B11R | Orthopox_B11R | Family | 83 | false | false | This family consists of several Orthopoxvirus B11R proteins of around 70 residues in length. The function of this family is unknown. B11R is also known as Protein OPG197. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF07033"
] | [
"Orthopox_B11R"
] | [
83
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Orthopoxvirus"
] | [
83
] | 1 | [] | [] | 0 | true | Family | Orthopoxvirus B11R | Orthopoxvirus B11R | Orthopox_B11R | 8 |
IPR009755 | 9,755 | Regulator of MON1-CCZ1 complex, C-terminal | RMC1_C | Domain | 3,100 | false | false | This entry represents the α-helical C terminus (approximately 160 residues) of RMC1, which is a component of the CCZ1-MON1 RAB7A guanine exchange factor (GEF) [ ]. This domain serves as a scaffold for CCZ1-MON1 recruitment and bridges the membrane and GEF complex. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF07035"
] | [
"RMC1_C"
] | [
3100
] | 1 | [] | [] | [] | 0 | [
"8c7g",
"8jbe",
"9l0d"
] | 3 | [
"PUB00090867"
] | [
"29038162"
] | [
"Systematic analysis of human cells lacking ATG8 proteins uncovers roles for GABARAPs and the CCZ1/MON1 regulator C18orf8/RMC1 in macro and selective autophagic flux."
] | [
2017
] | 1 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
3100
] | 1 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Zea mays"
] | [
8,
3,
1,
1,
6,
6,
6,
5,
3
] | 9 | true | Domain | Regulator of MON1-CCZ1 complex, C-terminal | Regulator of MON1-CCZ1 complex, C-terminal | RMC1_C | 9 |
IPR009757 | 9,757 | Circovirus 2, anti-apoptotic ORF4 | Circovirus2_Orf4 | Family | 14 | false | false | This family represents the anti-apoptotic ORF4 protein from Circovirus 2, which antagonises host cell apoptosis by interacting with host ferritin heavy chain (FHC). This protein physically binds host FHC, resulting in the reduction of FHC protein levels in host cells. The reduction of FHC concentration further inhibits... | [
"GO:0052150"
] | [
"symbiont-mediated perturbation of host apoptosis"
] | [
"biological_process"
] | 1 | [
"PFAM"
] | [
"PF07038"
] | [
"Circovir2_Orf4"
] | [
14
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00097765"
] | [
"27030984"
] | [
"The ORF4 protein of porcine circovirus type 2 antagonizes apoptosis by stabilizing the concentration of ferritin heavy chain through physical interaction."
] | [
2016
] | 1 | [] | [] | 0 | 0 | null | [
"Lymnaea stagnalis",
"Porcine circovirus 2"
] | [
1,
13
] | 2 | [] | [] | 0 | true | Family | Circovirus 2, anti-apoptotic ORF4 | Circovirus 2, anti-apoptotic ORF4 | Circovirus2_Orf4 | 8 |
IPR009758 | 9,758 | Protein of unknown function DUF1326 | DUF1326 | Family | 2,193 | false | false | This family consists of several hypothetical bacterial proteins and some uncharacterised archaeal proteins. Members of this family contain 5 highly conserved cysteine residues at their N-terminal. The function of this family is unknown. They contain a structure similar to a β-barrel fold. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF07040"
] | [
"DUF1326"
] | [
2193
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [
"IPR014581"
] | 0 | 1 | 0 | [
"Archaea",
"Bacteria",
"Geodia barretti",
"unclassified sequences"
] | [
70,
2047,
3,
73
] | 4 | [] | [] | 0 | true | Family | Protein of unknown function DUF1326 | Protein of unknown function DUF1326 | DUF1326 | 7 |
IPR009759 | 9,759 | Bacteriophage ES18, Gp24 | Phage_ES18_Gp24 | Family | 390 | false | false | This entry is represented by Bacteriophage ES18, Gp24. The characteristics of the protein distribution suggest prophage matches in addition to the phage matches. This family consists of several hypothetical bacterial proteins of around 115 residues in length, which seem to be specific to Escherichia coli. The function ... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF07041"
] | [
"DUF1327"
] | [
390
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Caudoviricetes",
"Panagrolaimus sp. ES5"
] | [
383,
6,
1
] | 3 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Bacteriophage ES18, Gp24 | Bacteriophage ES18, Gp24 | Phage_ES18_Gp24 | 2 |
IPR009760 | 9,760 | Protein of unknown function DUF1328 | DUF1328 | Family | 8,981 | false | false | This entry represents several hypothetical bacterial proteins of around 50 residues in length. The function of this family is unknown but is thought to be a membrane protein. | [
"GO:0005886"
] | [
"plasma membrane"
] | [
"cellular_component"
] | 1 | [
"HAMAP",
"PFAM",
"PIRSF"
] | [
"MF_01361",
"PF07043",
"PIRSF036466"
] | [
"UPF0391",
"DUF1328",
"UCP036466"
] | [
8894,
8806,
8476
] | 3 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Caudoviricetes",
"Eukaryota",
"Stenosarchaea group",
"unclassified sequences"
] | [
8597,
6,
5,
344,
29
] | 5 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Protein of unknown function DUF1328 | Protein of unknown function DUF1328 | DUF1328 | 1 |
IPR009762 | 9,762 | Circovirus 2, Orf10 | Circovirus2_Orf10 | Family | 10 | false | false | This family consists of several Circovirus proteins of around 35 residues in length. Members of this family are described as Orf10 proteins and their function is unknown. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF07048"
] | [
"DUF1331"
] | [
10
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Porcine circovirus 2"
] | [
10
] | 1 | [] | [] | 0 | true | Family | Circovirus 2, Orf10 | Circovirus 2, Orf10 | Circovirus2_Orf10 | 5 |
IPR009764 | 9,764 | Ovarian carcinoma immunoreactive antigen domain | OCIA_dom | Domain | 2,575 | false | false | This domain can be found in several ovarian carcinoma immunoreactive antigen (OCIA) and related eukaryotic sequences. The function of these proteins is unknown [ , ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF07051"
] | [
"OCIA"
] | [
2575
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00013440",
"PUB00013441"
] | [
"11162530",
"12445744"
] | [
"Molecular cloning of a novel human gene on chromosome 4p11 by immunoscreening of an ovarian carcinoma cDNA library.",
"Molecular cloning, identification and analysis of lung squamous cell carcinoma-related genes."
] | [
2001,
2002
] | 2 | [] | [] | 0 | 0 | null | [
"Metazoa"
] | [
2575
] | 1 | [
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
12,
2,
18,
8,
18
] | 5 | true | Domain | Ovarian carcinoma immunoreactive antigen domain | Ovarian carcinoma immunoreactive antigen domain | OCIA_dom | 3 |
IPR009765 | 9,765 | Pericardin-like repeat | Pericardin-like_rpt | Repeat | 115 | false | false | This entry represents a repeated sequence of around 34 residues in length, which is found in multiple copies in Drosophila pericardin and other extracellular matrix proteins [ , ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF07054"
] | [
"Pericardin_rpt"
] | [
115
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00020069",
"PUB00020070"
] | [
"12070098",
"1445780"
] | [
"Pericardin, a Drosophila type IV collagen-like protein is involved in the morphogenesis and maintenance of the heart epithelium during dorsal ectoderm closure.",
"Isolation and characterization of cDNA encoding a spicule matrix protein in Hemicentrotus pulcherrimus micromeres."
] | [
2002,
1992
] | 2 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota"
] | [
36,
79
] | 2 | [
"Drosophila melanogaster"
] | [
3
] | 1 | true | Repeat | Pericardin-like repeat | Pericardin-like repeat | Pericardin-like_rpt | 5 |
IPR009767 | 9,767 | DNA helicase, TraI type, C-terminal | DNA_helicase_TraI_C | Domain | 1,333 | false | false | This entry represents the C-terminal domain of the bacterial DNA helicase TraI. TraI is a bifunctional protein that catalyses the unwinding of duplex DNA as well as acts as a sequence-specific DNA trans-esterase, providing the site- and strand-specific nick required to initiate DNA transfer [ , , ]. This domain is esse... | [
"GO:0003677",
"GO:0003678",
"GO:0005524",
"GO:0016818"
] | [
"DNA binding",
"DNA helicase activity",
"ATP binding",
"hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"
] | [
"molecular_function",
"molecular_function",
"molecular_function",
"molecular_function"
] | 4 | [
"PFAM"
] | [
"PF07057"
] | [
"TraI_C"
] | [
1333
] | 1 | [
"EC",
"EC"
] | [
"5.6.2.-",
"5.6.2.3"
] | [
"EC:5.6.2.-",
"EC:5.6.2.3"
] | 2 | [
"3fld",
"5n8o",
"9f0x",
"9f0y",
"9f10",
"9f11",
"9f12"
] | 7 | [
"PUB00012990",
"PUB00051992",
"PUB00091215"
] | [
"11054423",
"19136009",
"28457609"
] | [
"F plasmid conjugative DNA transfer: the TraI helicase activity is essential for DNA strand transfer.",
"A novel fold in the TraI relaxase-helicase c-terminal domain is essential for conjugative DNA transfer.",
"Cryo-EM Structure of a Relaxase Reveals the Molecular Basis of DNA Unwinding during Bacterial Conjug... | [
2001,
2009,
2017
] | 3 | [] | [] | 0 | 0 | null | [
"Ecdysozoa",
"Gammaproteobacteria"
] | [
4,
1329
] | 2 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Domain | DNA helicase, TraI type, C-terminal | DNA helicase, TraI type, C-terminal | DNA_helicase_TraI_C | 5 |
IPR009769 | 9,769 | Protein ENHANCED DISEASE RESISTANCE 2, C-terminal | EDR2_C | Domain | 10,055 | false | false | This entry represents the C terminus of protein ENHANCED DISEASE RESISTANCE 2 (EDR2) from plants. EDR2 is a negative regulator of the salicylic acid- (SA-) mediated resistance to pathogens, including the biotrophic powdery mildew pathogens Golovinomyces cichoracearum and Blumeria graminis, and the downy mildew pathogen... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF07059"
] | [
"EDR2_C"
] | [
10055
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00078901",
"PUB00095635"
] | [
"16212604",
"17612410"
] | [
"Regulation of plant defense responses in Arabidopsis by EDR2, a PH and START domain-containing protein.",
"EDR2 negatively regulates salicylic acid-based defenses and cell death during powdery mildew infections of Arabidopsis thaliana."
] | [
2005,
2007
] | 2 | [] | [] | 0 | 0 | null | [
"Eukaryota",
"Kistimonas scapharcae",
"marine metagenome"
] | [
10053,
1,
1
] | 3 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
77,
37,
126
] | 3 | true | Domain | Protein ENHANCED DISEASE RESISTANCE 2, C-terminal | Protein ENHANCED DISEASE RESISTANCE 2, C-terminal | EDR2_C | 1 |
IPR009771 | 9,771 | RIC1, C-terminal alpha solenoid region | RIC1_C | Domain | 4,998 | false | false | This entry represents the C-terminal α-helical solenoid region of RIC1. This entry represents RIC1 (Ribosomal control protein1) and has been identified in yeast as a Golgi protein involved in retrograde transport to the cis-Golgi network. It forms a heterodimer with Rgp1 and functions as a guanyl-nucleotide exchange fa... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF07064"
] | [
"RIC1"
] | [
4998
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-CEL-6811438",
"R-CEL-6811440",
"R-CEL-8876198",
"R-DME-6811440",
"R-DME-8876198",
"R-DRE-6811438",
"R-HSA-6811438",
"R-HSA-6811440",
"R-HSA-8876198",
"R-MMU-6811438",
"R-MMU-6811440",
"R-MMU-8876198",
"R-SCE-6811440",
"R-SCE-8876198",
"R-SPO-6811440",
"R-SPO-8876198"
] | [
"REACTOME:R-CEL-6811438",
"REACTOME:R-CEL-6811440",
"REACTOME:R-CEL-8876198",
"REACTOME:R-DME-6811440",
"REACTOME:R-DME-8876198",
"REACTOME:R-DRE-6811438",
"REACTOME:R-HSA-6811438",
"REACTOME:R-HSA-6811440",
"REACTOME:R-HSA-8876198",
"REACTOME:R-MMU-6811438",
"REACTOME:R-MMU-6811440",
"REACTOM... | 16 | [
"9ayr"
] | 1 | [
"PUB00035455",
"PUB00053774",
"PUB00053775"
] | [
"10990452",
"11689439",
"11160819"
] | [
"Ric1p and Rgp1p form a complex that catalyses nucleotide exchange on Ypt6p.",
"An effector of Ypt6p binds the SNARE Tlg1p and mediates selective fusion of vesicles with late Golgi membranes.",
"Ric1p and the Ypt6p GTPase function in a common pathway required for localization of trans-Golgi network membrane pro... | [
2000,
2001,
2001
] | 3 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
4998
] | 1 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Saccharomyces cerevisiae (strai... | [
14,
1,
2,
1,
3,
4,
1,
3,
4,
1,
1,
52
] | 12 | true | Domain | RIC1, C-terminal alpha solenoid region | RIC1, C-terminal alpha solenoid region | RIC1_C | 3 |
IPR009772 | 9,772 | Cell division cycle protein 123 | CDC123 | Family | 5,319 | false | false | This entry represents the eukaryotic cell division cycle 123 (Cdc123) family, also known as the translation initiation factor eIF2 assembly family. These proteins are approximately 330 residues long. Budding yeast Cdc123 regulates the cell cycle in a nutrient dependent manner [ ]. Cdc123 is member of the ATP grasp fami... | [] | [] | [] | 0 | [
"PFAM",
"PIRSF",
"PANTHER"
] | [
"PF07065",
"PIRSF007807",
"PTHR15323"
] | [
"D123",
"Cdc123",
""
] | [
5309,
829,
5007
] | 3 | [] | [] | [] | 0 | [
"4zgn",
"4zgo",
"4zgp",
"4zgq",
"8phd",
"8phv"
] | 6 | [
"PUB00012992",
"PUB00019384",
"PUB00153159",
"PUB00153160"
] | [
"11699637",
"15319434",
"35031321",
"37507029"
] | [
"Reversion of temperature-sensitive mutation by inhibition of proteasome-mediated degradation of mutated D123 protein.",
"Cdc123 and checkpoint forkhead associated with RING proteins control the cell cycle by controlling eIF2gamma abundance.",
"Stepwise assembly of the eukaryotic translation initiation factor 2... | [
2001,
2004,
2022,
2023
] | 4 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Viruses",
"metagenomes"
] | [
80,
5174,
60,
5
] | 4 | [
"Arabidopsis thaliana",
"Danio rerio",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)",
"Schizosaccharomyces pombe (st... | [
6,
2,
5,
2,
1,
1,
6,
1,
1,
4
] | 10 | true | Family | Cell division cycle protein 123 | Cell division cycle protein 123 | CDC123 | 4 |
IPR009773 | 9,773 | Lactococcus phage 712, M3 | Lactococcus_phage_712_M3 | Family | 273 | false | false | This family consists of several Lactococcus bacteriophage 712, middle-3 (M3) proteins of around 160 residues in length. The characteristics of the protein distribution suggest prophage matches in addition to the phage matches. The function of this family is unknown. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF07066"
] | [
"DUF3882"
] | [
273
] | 1 | [
"GP"
] | [
"GenProp0208"
] | [
"GP:GenProp0208"
] | 1 | [
"4ktw",
"4ktz"
] | 2 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Caudoviricetes"
] | [
31,
242
] | 2 | [] | [] | 0 | true | Family | Lactococcus phage 712, M3 | Lactococcus phage 712, M3 | Lactococcus_phage_712_M3 | 4 |
IPR009774 | 9,774 | Streptococcus phage 7201, Orf18 | Phage_7201_Orf18 | Family | 150 | false | false | This family consists of several hypothetical Streptococcus thermophilus bacteriophage proteins of around 235 residues in length. The function of this family is unknown. | [] | [] | [] | 0 | [
"PFAM",
"PIRSF"
] | [
"PF07067",
"PIRSF024009"
] | [
"DUF1340",
"DUF1340"
] | [
150,
59
] | 2 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Viruses"
] | [
8,
142
] | 2 | [] | [] | 0 | true | Family | Streptococcus phage 7201, Orf18 | Streptococcus phage 7201, Orf18 | Phage_7201_Orf18 | 7 |
IPR009775 | 9,775 | Envelope small membrane protein | GP2b | Family | 425 | false | false | This entry includes a group of envelope small membrane protein, including GP2b (also known as protein E) from Porcine reproductive and respiratory syndrome virus. It may function as a viroporin in the virion envelope that facilitates uncoating of the virus in order to release the genomic RNA into the cytoplasm for subs... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF07069"
] | [
"PRRSV_2b"
] | [
425
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00074859"
] | [
"16904148"
] | [
"The small envelope protein of porcine reproductive and respiratory syndrome virus possesses ion channel protein-like properties."
] | [
2006
] | 1 | [] | [] | 0 | 0 | null | [
"Arteriviridae"
] | [
425
] | 1 | [] | [] | 0 | true | Family | Envelope small membrane protein | Envelope small membrane protein | GP2b | 3 |
IPR009776 | 9,776 | Sporulation stage 0, protein M | Spore_0_M | Family | 5,967 | false | false | This family consists of several bacterial SpoOM proteins which are thought to control sporulation in Bacillus subtilis.Spo0M exerts certain negative effects on sporulation and its gene expression is controlled by sigmaH [ ]. | [] | [] | [] | 0 | [
"PFAM",
"PANTHER"
] | [
"PF07070",
"PTHR40053"
] | [
"Spo0M",
""
] | [
5964,
5702
] | 2 | [] | [] | [] | 0 | [
"5cl2"
] | 1 | [
"PUB00012994"
] | [
"9795118"
] | [
"A novel sporulation-control gene (spo0M) of Bacillus subtilis with a sigmaH-regulated promoter."
] | [
1998
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Halobacteriales",
"ecological metagenomes",
"uncultured Caudovirales phage"
] | [
5849,
2,
105,
7,
4
] | 5 | [] | [] | 0 | true | Family | Sporulation stage 0, protein M | Sporulation stage 0, protein M | Spore_0_M | 4 |
IPR009777 | 9,777 | Cell division protein ZapD | ZapD | Family | 3,909 | false | false | Cell division protein ZapD enhances FtsZ-ring assembly. It directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity [ ]. | [] | [] | [] | 0 | [
"HAMAP",
"PFAM",
"PANTHER"
] | [
"MF_01092",
"PF07072",
"PTHR39455"
] | [
"ZapD",
"ZapD",
""
] | [
3727,
3905,
3902
] | 3 | [] | [] | [] | 0 | [
"2oez",
"5dko",
"5gnp",
"5imj",
"5koa"
] | 5 | [
"PUB00060570"
] | [
"22505682"
] | [
"Identification of ZapD as a cell division factor that promotes the assembly of FtsZ in Escherichia coli."
] | [
2012
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"unclassified sequences"
] | [
3849,
7,
53
] | 3 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Cell division protein ZapD | Cell division protein ZapD | ZapD | 8 |
IPR009778 | 9,778 | Modulator of Rho-dependent transcription termination | ROF | Family | 2,021 | false | false | This family consists of several bacterial modulator of Rho-dependent transcription termination (ROF) proteins. ROF binds transcription termination factor Rho and inhibits Rho-dependent termination in vivo [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF07073"
] | [
"ROF"
] | [
2021
] | 1 | [] | [] | [] | 0 | [
"1sg5",
"6jie",
"8ptm",
"8ptn",
"8pto",
"8ptp",
"8w8d"
] | 7 | [
"PUB00012995"
] | [
"9723924"
] | [
"An Escherichia coli gene (yaeO) suppresses temperature-sensitive mutations in essential genes by modulating Rho-dependent transcription termination."
] | [
1998
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Ecdysozoa",
"ecological metagenomes"
] | [
2013,
3,
5
] | 3 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Modulator of Rho-dependent transcription termination | Modulator of Rho-dependent transcription termination | ROF | 1 |
IPR009779 | 9,779 | Translocon-associated protein subunit gamma | SSR3 | Family | 2,548 | false | false | The translocon-associated protein (TRAP, also known as the signal sequence receptor) complex is required for the efficient translocation of secretory and membrane proteins in the endoplasmic reticulum, and is also involved in the endoplasmic reticulum stress-mediated unfolded protein response pathway. This entry repres... | [
"GO:0006614",
"GO:0016020"
] | [
"SRP-dependent cotranslational protein targeting to membrane",
"membrane"
] | [
"biological_process",
"cellular_component"
] | 2 | [
"PFAM"
] | [
"PF07074"
] | [
"TRAP-gamma"
] | [
2548
] | 1 | [
"REACTOME"
] | [
"R-HSA-1799339"
] | [
"REACTOME:R-HSA-1799339"
] | 1 | [
"8b5l",
"8b6l",
"8bf9",
"8btk",
"8rjc",
"8rjd"
] | 6 | [
"PUB00077045"
] | [
"21246656"
] | [
"Translocon-associated protein subunit Trap-γ/Ssr3 is required for vascular network formation in the mouse placenta."
] | [
2011
] | 1 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
2548
] | 1 | [
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
1,
1,
1,
3,
3,
4
] | 6 | true | Family | Translocon-associated protein subunit gamma | Translocon-associated protein subunit gamma | SSR3 | 8 |
IPR009780 | 9,780 | Protein of unknown function DUF1344 | DUF1344 | Family | 849 | false | false | This family consists of several short, hypothetical bacterial proteins of around 80 residues in length. Members of this family are found in rhizobacteria. The function of this family is unknown. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF07076"
] | [
"DUF1344"
] | [
849
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"ecological metagenomes"
] | [
845,
4
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function DUF1344 | Protein of unknown function DUF1344 | DUF1344 | 6 |
IPR009781 | 9,781 | Virulence factor BPSS1818 | BPSS1818 | Domain | 5,483 | false | false | This entry represents BPSS1818, a virulence factor required for full Burkholderia pseudomallei pathogenesis in vivo. BPSS1818 is involved in indirect modulation of mammalian host cell tubulin, probably in concert with other bacterial components [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF07077"
] | [
"DUF1345"
] | [
5483
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00159059"
] | [
"33772012"
] | [
"The Burkholderia pseudomallei intracellular 'TRANSITome'."
] | [
2021
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"ecological metagenomes"
] | [
5458,
2,
23
] | 3 | [] | [] | 0 | true | Domain | Virulence factor BPSS1818 | Virulence factor BPSS1818 | BPSS1818 | 7 |
IPR009782 | 9,782 | UAP56-interacting factor | FYTTD1 | Family | 1,203 | false | false | UAP56-interacting factor, also known as UIF, is a mRNA export adaptor that works together with adaptor REF/ALY. It is required for mRNA export from the nucleus to the cytoplasm [ ]. | [
"GO:0003729",
"GO:0006406"
] | [
"mRNA binding",
"mRNA export from nucleus"
] | [
"molecular_function",
"biological_process"
] | 2 | [
"PANTHER"
] | [
"PTHR21038"
] | [
""
] | [
1203
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-BTA-159236",
"R-BTA-72187",
"R-BTA-73856",
"R-GGA-72187",
"R-GGA-73856",
"R-HSA-159236",
"R-HSA-72187",
"R-HSA-73856",
"R-MMU-159236",
"R-MMU-72187",
"R-MMU-73856",
"R-RNO-159236",
"R-RNO-72187",
"R-RNO-73856"
] | [
"REACTOME:R-BTA-159236",
"REACTOME:R-BTA-72187",
"REACTOME:R-BTA-73856",
"REACTOME:R-GGA-72187",
"REACTOME:R-GGA-73856",
"REACTOME:R-HSA-159236",
"REACTOME:R-HSA-72187",
"REACTOME:R-HSA-73856",
"REACTOME:R-MMU-159236",
"REACTOME:R-MMU-72187",
"REACTOME:R-MMU-73856",
"REACTOME:R-RNO-159236",
... | 14 | [] | 0 | [
"PUB00074858"
] | [
"19836239"
] | [
"UIF, a New mRNA export adaptor that works together with REF/ALY, requires FACT for recruitment to mRNA."
] | [
2009
] | 1 | [] | [] | 0 | 0 | null | [
"Eumetazoa"
] | [
1203
] | 1 | [
"Danio rerio",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
1,
4,
2,
8
] | 4 | true | Family | UAP56-interacting factor | UAP56-interacting factor | FYTTD1 | 5 |
IPR009783 | 9,783 | Protein of unknown function DUF1348 | DUF1348 | Family | 7,766 | false | false | This family consists of several highly conserved hypothetical proteins of around 150 residues in length. The function of this family is unknown. | [] | [] | [] | 0 | [
"PFAM",
"PANTHER"
] | [
"PF07080",
"PTHR31757"
] | [
"DUF1348",
""
] | [
7765,
7727
] | 2 | [] | [] | [] | 0 | [
"2imj"
] | 1 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"metagenomes"
] | [
8,
6435,
1304,
19
] | 4 | [
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)"
] | [
1
] | 1 | true | Family | Protein of unknown function DUF1348 | Protein of unknown function DUF1348 | DUF1348 | 5 |
IPR009784 | 9,784 | Protein of unknown function DUF1349 | DUF1349 | Family | 7,426 | false | false | This family consists of several hypothetical bacterial proteins but contains one sequence Ree1 ( ) from Saccharomyces cerevisiae [ ]. Members of this family are typically around 200 residues in length. The function of this family is unknown. | [] | [] | [] | 0 | [
"PFAM",
"PANTHER"
] | [
"PF07081",
"PTHR35332"
] | [
"DUF1349",
""
] | [
7412,
7031
] | 2 | [] | [] | [] | 0 | [
"3mep",
"3o12"
] | 2 | [
"PUB00086893"
] | [
"18851946"
] | [
"Novel Ree1 regulates the expression of ENO1 via the Snf1 complex pathway in Saccharomyces cerevisiae."
] | [
2008
] | 1 | [] | [
"IPR015987"
] | 0 | 1 | 0 | [
"Bacteria",
"Eukaryota",
"Siphoviridae sp. ctcfw7",
"Stenosarchaea group",
"metagenomes"
] | [
5199,
2178,
1,
16,
32
] | 5 | [
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)"
] | [
1,
1
] | 2 | true | Family | Protein of unknown function DUF1349 | Protein of unknown function DUF1349 | DUF1349 | 8 |
IPR009785 | 9,785 | Lactobacillus prophage Lj928, Orf309 | Prophage_Lj928_Orf309 | Family | 913 | false | false | This entry is represented by Lactobacillus prophage Lj928, Orf309. The characteristics of the protein distribution suggest prophage matches in addition to the phage matches. This family consists of several bacterial and phage proteins of around 230 residues in length. The function of this family is unknown. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF07083"
] | [
"DUF1351"
] | [
913
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Viruses",
"metagenomes"
] | [
713,
198,
2
] | 3 | [] | [] | 0 | true | Family | Lactobacillus prophage Lj928, Orf309 | Lactobacillus prophage Lj928, Orf309 | Prophage_Lj928_Orf309 | 6 |
IPR009786 | 9,786 | Spot 14 family | Spot_14 | Family | 2,617 | false | false | The Spot 14 family includes thyroid hormone-inducible hepatic protein (Spot 14), Mid1-interacting protein and related sequneces. Mainly expressed in tissues that synthesise triglycerides, the mRNA coding for Spot 14 has been shown to be increased in rat liver by insulin, dietary carbohydrates, glucose in hepatocyte cul... | [] | [] | [] | 0 | [
"PFAM",
"PANTHER"
] | [
"PF07084",
"PTHR14315"
] | [
"Spot_14",
""
] | [
2614,
2566
] | 2 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-DRE-200425",
"R-HSA-200425",
"R-HSA-9841922",
"R-MMU-200425",
"R-RNO-200425"
] | [
"REACTOME:R-DRE-200425",
"REACTOME:R-HSA-200425",
"REACTOME:R-HSA-9841922",
"REACTOME:R-MMU-200425",
"REACTOME:R-RNO-200425"
] | 5 | [
"3ont"
] | 1 | [
"PUB00012997",
"PUB00012998",
"PUB00054284"
] | [
"9003802",
"11564699",
"15070402"
] | [
"Cloning and initial characterization of human and mouse Spot 14 genes.",
"Spot 14 gene deletion increases hepatic de novo lipogenesis.",
"Mig12, a novel Opitz syndrome gene product partner, is expressed in the embryonic ventral midline and co-operates with Mid1 to bundle and stabilize microtubules."
] | [
1997,
2001,
2004
] | 3 | [] | [] | 0 | 0 | null | [
"Eumetazoa",
"Paenibacillus sediminis"
] | [
2616,
1
] | 2 | [
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
6,
2,
2,
7,
8
] | 5 | true | Family | Spot 14 family | Spot 14 family | Spot_14 | 4 |
IPR009787 | 9,787 | Protein jagunal | Jagunal | Family | 2,397 | false | false | Protein jagunal is required for endoplasmic reticulum organisation and proper vesicular traffic during Drosophila oogenesis [ ]. | [
"GO:0007029",
"GO:0005789"
] | [
"endoplasmic reticulum organization",
"endoplasmic reticulum membrane"
] | [
"biological_process",
"cellular_component"
] | 2 | [
"PFAM",
"PANTHER"
] | [
"PF07086",
"PTHR20955"
] | [
"Jagunal",
""
] | [
2292,
2287
] | 2 | [] | [] | [] | 0 | [
"6wvd"
] | 1 | [
"PUB00068041"
] | [
"17389229"
] | [
"Jagunal is required for reorganizing the endoplasmic reticulum during Drosophila oogenesis."
] | [
2007
] | 1 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
2397
] | 1 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Zea mays"
] | [
2,
1,
2,
2,
3,
2,
5,
2,
4
] | 9 | true | Family | Protein jagunal | Protein jagunal | Jagunal | 2 |
IPR009790 | 9,790 | Transmembrane protein 106 | TMEM106 | Family | 3,229 | false | false | This family includes Transmembrane protein 106A/B/C, type II transmembrane proteins which have homology to the late embryogenesis abundant-2 (LEA-2) domain [ ]. TMEM106A has been identified as a key factor to regulate macrophage activation and a tumour suppressor in gastric, renal cancer and nonsmall-cell lung carcinom... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR28556"
] | [
""
] | [
3229
] | 1 | [] | [] | [] | 0 | [
"7qvc",
"7qvf",
"7qwg",
"7qwl",
"7qwm",
"7saq",
"7sar",
"7sas",
"7tmc",
"7u10",
"7u11",
"7u12",
"7u13",
"7u14",
"7u15",
"7u16",
"7u17",
"7u18",
"7x83",
"7x84",
"8b7d",
"8f9k",
"8j7n",
"8j7p",
"8otd",
"8ote",
"8x5h",
"9fnb"
] | 28 | [
"PUB00070924",
"PUB00100166",
"PUB00100167",
"PUB00100168",
"PUB00100169"
] | [
"24357581",
"34347309",
"29131025",
"30456879",
"23136129"
] | [
"The FTLD risk factor TMEM106B and MAP6 control dendritic trafficking of lysosomes.",
"TMEM106B in humans and Vac7 and Tag1 in yeast are predicted to be lipid transfer proteins.",
"TMEM106a is a Novel Tumor Suppressor in Human Renal Cancer.",
"TMEM106A inhibits cell proliferation, migration, and induces apopt... | [
2014,
2022,
2017,
2018,
2013
] | 5 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
3229
] | 1 | [
"Danio rerio",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
11,
24,
12,
11
] | 4 | true | Family | Transmembrane protein 106 | Transmembrane protein 106 | TMEM106 | 3 |
IPR009791 | 9,791 | Protein of unknown function DUF1357 | DUF1357 | Family | 191 | false | false | This entry represents a family of hypothetical proteins of around 225 residues in length found in Borrelia species. The function of this family is unknown. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF07094"
] | [
"DUF1357"
] | [
191
] | 1 | [] | [] | [] | 0 | [
"8php",
"8phq",
"8phr",
"8phs",
"8pht",
"8phu",
"8pkh",
"8qo0",
"8qo1"
] | 9 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Borreliaceae"
] | [
191
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF1357 | Protein of unknown function DUF1357 | DUF1357 | 1 |
IPR009792 | 9,792 | Transmembrane protein 242 | TMEM242 | Family | 1,567 | false | false | This family consists of several hypothetical eukaryotic proteins of around 125 residues in length. The function of this family is unknown. | [] | [] | [] | 0 | [
"PFAM",
"PANTHER"
] | [
"PF07096",
"PTHR13141"
] | [
"DUF1358",
""
] | [
1529,
1457
] | 2 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Acidaminococcus fermentans",
"Eukaryota"
] | [
2,
1565
] | 2 | [
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
1,
1,
4,
2,
1,
4
] | 6 | true | Family | Transmembrane protein 242 | Transmembrane protein 242 | TMEM242 | 6 |
IPR009793 | 9,793 | Protein of unknown function DUF1361 | DUF1361 | Family | 2,490 | false | false | This family consists of several hypothetical bacterial proteins of around 200 residues in length. The function of this family is unknown although some members are annotated as being putative integral membrane proteins. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF07099"
] | [
"DUF1361"
] | [
2490
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"ecological metagenomes"
] | [
2486,
4
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function DUF1361 | Protein of unknown function DUF1361 | DUF1361 | 3 |
IPR009794 | 9,794 | Anabaena sensory rhodopsin transducer | ASRT | Family | 958 | false | false | This entry represents a family of proteins found in bacteria and some archaeal species, including the Anabaena sensory rhodopsin transducer (ASRT) and the hypothetical protein TM1070 from Thermotoga maritima. ASRT, likely to bind sugars or related metabolites, is comprised of a single globular domain with an eight-stra... | [] | [] | [] | 0 | [
"PFAM",
"PIRSF"
] | [
"PF07100",
"PIRSF008711"
] | [
"ASRT",
"UCP008711"
] | [
958,
779
] | 2 | [] | [] | [] | 0 | [
"1nc7",
"2ii7",
"2ii8",
"2ii9",
"2iia"
] | 5 | [
"PUB00041719",
"PUB00100872",
"PUB00100873"
] | [
"17289074",
"12622809",
"19682383"
] | [
"Crystal structure of the Anabaena sensory rhodopsin transducer.",
"Demonstration of a sensory rhodopsin in eubacteria.",
"The Anabaena sensory rhodopsin transducer defines a novel superfamily of prokaryotic small-molecule binding domains."
] | [
2007,
2003,
2009
] | 3 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Stenosarchaea group",
"ecological metagenomes"
] | [
906,
2,
44,
6
] | 4 | [] | [] | 0 | true | Family | Anabaena sensory rhodopsin transducer | Anabaena sensory rhodopsin transducer | ASRT | 2 |
IPR009795 | 9,795 | Protein of unknown function DUF1363 | DUF1363 | Family | 14 | false | false | This family consists of several Trypanosoma brucei putative variant specific antigen proteins of around 80 residues in length. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF07101"
] | [
"DUF1363"
] | [
14
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Trypanosoma brucei"
] | [
14
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF1363 | Protein of unknown function DUF1363 | DUF1363 | 3 |
IPR009796 | 9,796 | Protein of unknown function DUF1366 | DUF1366 | Family | 311 | false | false | This family consists of several hypothetical Streptococcus bacteriophage proteins of around 130 residues in length. One of the sequences in this family, from phage Sfi11 ( ) is known as Gp149. The function of this family is unknown. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF07104"
] | [
"DUF1366"
] | [
311
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Viruses"
] | [
177,
134
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function DUF1366 | Protein of unknown function DUF1366 | DUF1366 | 8 |
IPR009797 | 9,797 | Protein of unknown function DUF1367 | DUF1367 | Family | 2,090 | false | false | This family consists of several highly conserved, hypothetical bacterial and phage proteins of around 200 resides in length. The function of this family is unknown. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF07105"
] | [
"DUF1367"
] | [
2090
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Neoptera",
"Viruses",
"metagenomes"
] | [
2018,
2,
48,
22
] | 4 | [] | [] | 0 | true | Family | Protein of unknown function DUF1367 | Protein of unknown function DUF1367 | DUF1367 | 5 |
IPR009798 | 9,798 | Wound-induced protein Wun1-like | Wun1-like | Family | 1,693 | false | false | This entry consists of several plant wound-induced protein sequences related to WI12 from Mesembryanthemum crystallinum (Common ice plant) ( ). Wounding, methyl jasmonate, and pathogen infection is known to induce local WI12 expression. WI12 expression is also thought to be developmentally controlled in the placenta an... | [] | [] | [] | 0 | [
"PFAM",
"PANTHER"
] | [
"PF07107",
"PTHR33703"
] | [
"WI12",
""
] | [
1670,
1665
] | 2 | [] | [] | [] | 0 | [] | 0 | [
"PUB00013002"
] | [
"11598226"
] | [
"Environmental and developmental regulation of the wound-induced cell wall protein WI12 in the halophyte ice plant."
] | [
2001
] | 1 | [] | [
"IPR016533"
] | 0 | 1 | 0 | [
"Embryophyta"
] | [
1693
] | 1 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
7,
11,
12
] | 3 | true | Family | Wound-induced protein Wun1-like | Wound-induced protein Wun1-like | Wun1-like | 4 |
IPR009799 | 9,799 | EthD domain | EthD_dom | Domain | 12,408 | false | false | This domain is found in several bacterial and fungal sequences which are related to the EthD (Ethyl tert-butyl ether degradation) protein of Rhodococcus ruber . In Rhodococcus ruber, EthD is thought to be involved in the degradation of ethyl tert-butyl ether (ETBE) [ ]. In Aspergillus terreus, EthD is part of the Pks1 ... | [
"GO:0016491"
] | [
"oxidoreductase activity"
] | [
"molecular_function"
] | 1 | [
"PFAM",
"NCBIFAM"
] | [
"PF07110",
"TIGR02118"
] | [
"EthD",
""
] | [
10919,
6889
] | 2 | [
"EC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC"... | [
"4.1.1.-",
"PWY-3385",
"PWY-3542",
"PWY-5113",
"PWY-5163",
"PWY-5706",
"PWY-5826",
"PWY-5870",
"PWY-5871",
"PWY-5872",
"PWY-5873",
"PWY-5956",
"PWY-6055",
"PWY-6262",
"PWY-6309",
"PWY-6322",
"PWY-6340",
"PWY-6627",
"PWY-6633",
"PWY-6935",
"PWY-6959",
"PWY-7007",
"PWY-7154... | [
"EC:4.1.1.-",
"METACYC:PWY-3385",
"METACYC:PWY-3542",
"METACYC:PWY-5113",
"METACYC:PWY-5163",
"METACYC:PWY-5706",
"METACYC:PWY-5826",
"METACYC:PWY-5870",
"METACYC:PWY-5871",
"METACYC:PWY-5872",
"METACYC:PWY-5873",
"METACYC:PWY-5956",
"METACYC:PWY-6055",
"METACYC:PWY-6262",
"METACYC:PWY-6... | 43 | [
"2ftr",
"3bf4",
"9iku",
"9ilo",
"9im9",
"9ipr",
"9ir1",
"9iwu"
] | 8 | [
"PUB00015565",
"PUB00081405",
"PUB00095152",
"PUB00095154",
"PUB00095157",
"PUB00163294"
] | [
"11673424",
"24009710",
"19549600",
"7665560",
"28447400",
"31028901"
] | [
"Cloning of a genetically unstable cytochrome P-450 gene cluster involved in degradation of the pollutant ethyl tert-butyl ether by Rhodococcus ruber.",
"Heterologous reconstitution of the intact geodin gene cluster in Aspergillus nidulans through a simple and versatile PCR based approach.",
"Physically discret... | [
2001,
2013,
2009,
1995,
2017,
2019
] | 6 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"metagenomes"
] | [
255,
6379,
5627,
147
] | 4 | [
"Arabidopsis thaliana"
] | [
1
] | 1 | true | Domain | EthD domain | EthD domain | EthD_dom | 9 |
IPR009800 | 9,800 | Coiled-coil alpha-helical rod protein 1 | HCR | Family | 1,123 | false | false | This entry represents the coiled-coil α-helical rod protein 1 (HCR) from animals. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation [ ]. | [
"GO:0030154"
] | [
"cell differentiation"
] | [
"biological_process"
] | 1 | [
"PFAM",
"PANTHER"
] | [
"PF07111",
"PTHR46822"
] | [
"HCR",
""
] | [
1076,
1094
] | 2 | [] | [] | [] | 0 | [] | 0 | [
"PUB00013005"
] | [
"11875053"
] | [
"Coding haplotype analysis supports HCR as the putative susceptibility gene for psoriasis at the MHC PSORS1 locus."
] | [
2002
] | 1 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
1123
] | 1 | [
"Danio rerio",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
2,
96,
3,
7
] | 4 | true | Family | Coiled-coil alpha-helical rod protein 1 | Coiled-coil alpha-helical rod protein 1 | HCR | 1 |
IPR009801 | 9,801 | Transmembrane protein 126 | TMEM126 | Family | 1,628 | false | false | This entry includes the transmembrane protein 126 A/B (TMEM126A/B) from animals. Human TMEM126B participates in constructing the membrane arm of mitochondrial respiratory complex I [ ]. | [] | [] | [] | 0 | [
"PFAM",
"PANTHER"
] | [
"PF07114",
"PTHR16296"
] | [
"TMEM126",
""
] | [
1621,
1599
] | 2 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-DME-6799198",
"R-HSA-6799198",
"R-MMU-6799198",
"R-RNO-6799198"
] | [
"REACTOME:R-DME-6799198",
"REACTOME:R-HSA-6799198",
"REACTOME:R-MMU-6799198",
"REACTOME:R-RNO-6799198"
] | 4 | [] | 0 | [
"PUB00077052"
] | [
"24191001"
] | [
"Assembly factors for the membrane arm of human complex I."
] | [
2013
] | 1 | [] | [] | 0 | 0 | null | [
"Eumetazoa"
] | [
1628
] | 1 | [
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
1,
1,
6,
4,
5
] | 5 | true | Family | Transmembrane protein 126 | Transmembrane protein 126 | TMEM126 | 9 |
IPR009803 | 9,803 | Protein of unknown function DUF1373 | DUF1373 | Family | 262 | false | false | This family consists of several hypothetical proteins which seem to be specific to Oryzias latipes (Japanese ricefish). Members of this family are typically around 200 residues in length. The function of this family is unknown. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF07117"
] | [
"DUF1373"
] | [
262
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Euteleosteomorpha"
] | [
262
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF1373 | Protein of unknown function DUF1373 | DUF1373 | 8 |
IPR009804 | 9,804 | Sulfolobus islandicus filamentous virus, Orf14 | SIFV_Orf14 | Family | 55 | false | false | This family consists of several hypothetical Sulfolobus virus proteins of around 100 residues in length. The function of this family is unknown. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF07118"
] | [
"DUF1374"
] | [
55
] | 1 | [] | [] | [] | 0 | [
"2h36",
"3df6",
"3djw",
"6exp",
"6thh"
] | 5 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Oryza sativa subsp. indica",
"Viruses",
"marine sediment metagenome"
] | [
21,
1,
32,
1
] | 4 | [] | [] | 0 | true | Family | Sulfolobus islandicus filamentous virus, Orf14 | Sulfolobus islandicus filamentous virus, Orf14 | SIFV_Orf14 | 1 |
IPR009805 | 9,805 | Variable length PCR target | Variable_length_PCR_target | Repeat | 46 | false | false | This entry represents a 29 residue repeated sequence which seem to be specific to the Ehrlichia chaffeensis variable length PCR target (VLPT) protein. E. chaffeensis is a tick-transmitted rickettsial agent and is responsible for human monocytic ehrlichiosis (HME). The function of this family is unknown [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF07122"
] | [
"VLPT"
] | [
46
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00013006"
] | [
"12496165"
] | [
"Molecular heterogeneity of Ehrlichia chaffeensis isolates determined by sequence analysis of the 28-kilodalton outer membrane protein genes and other regions of the genome."
] | [
2003
] | 1 | [] | [] | 0 | 0 | null | [
"Ehrlichia chaffeensis"
] | [
46
] | 1 | [] | [] | 0 | true | Repeat | Variable length PCR target | Variable length PCR target | Variable_length_PCR_target | 8 |
IPR009806 | 9,806 | Photosystem II PsbW, class 2 | PSII_PsbW_class2 | Family | 1,116 | false | false | This family represents the low molecular weight transmembrane protein PsbW found in PSII, where it is a subunit of the oxygen-evolving complex. PsbW appears to have several roles, including guiding PSII biogenesis and assembly, stabilising dimeric PSII [ ], and facilitating PSII repair after photo-inhibition [ ]. There... | [
"GO:0015979",
"GO:0009507",
"GO:0009523"
] | [
"photosynthesis",
"chloroplast",
"photosystem II"
] | [
"biological_process",
"cellular_component",
"cellular_component"
] | 3 | [
"PFAM",
"PANTHER"
] | [
"PF07123",
"PTHR34552"
] | [
"PsbW",
""
] | [
1116,
1029
] | 2 | [
"GP"
] | [
"GenProp0661"
] | [
"GP:GenProp0661"
] | 1 | [
"3jcu",
"5mdx",
"5xnl",
"5xnm",
"6kac",
"6kad",
"6kaf",
"6yp7",
"7oui",
"7pi0",
"7pi5",
"7pin",
"7piw",
"7pnk",
"8bd3",
"8c29",
"8z9d",
"9gnw",
"9hd7",
"9is4",
"9le7",
"9le8",
"9lk4",
"9lk5"
] | 24 | [
"PUB00015357",
"PUB00015358",
"PUB00015359",
"PUB00015376",
"PUB00015377",
"PUB00097583",
"PUB00152828"
] | [
"12518057",
"15100025",
"14871485",
"10950961",
"9335523",
"30076221",
"33846594"
] | [
"Crystal structure of oxygen-evolving photosystem II from Thermosynechococcus vulcanus at 3.7-A resolution.",
"The evolutionary development of the protein complement of photosystem 2.",
"The low molecular mass subunits of the photosynthetic supracomplex, photosystem II.",
"The low molecular mass PsbW protein ... | [
2003,
2004,
2004,
2000,
1997,
2018,
2021
] | 7 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota"
] | [
9,
1107
] | 2 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
4,
2,
10
] | 3 | true | Family | Photosystem II PsbW, class 2 | Photosystem II PsbW, class 2 | PSII_PsbW_class2 | 4 |
IPR009807 | 9,807 | Phytoreovirus outer capsid P8 | Phytoreo_P8 | Family | 14 | false | false | This family consists of several Phytoreovirus outer capsid protein P8 sequences [ ]. | [
"GO:0005198",
"GO:0019028"
] | [
"structural molecule activity",
"viral capsid"
] | [
"molecular_function",
"cellular_component"
] | 2 | [
"PFAM"
] | [
"PF07124"
] | [
"Phytoreo_P8"
] | [
14
] | 1 | [] | [] | [] | 0 | [
"1uf2"
] | 1 | [
"PUB00013008"
] | [
"9343255"
] | [
"Details of the arrangement of the outer capsid of rice dwarf phytoreovirus, as visualized by two-dimensional crystallography."
] | [
1997
] | 1 | [] | [] | 0 | 0 | null | [
"Phytoreovirus"
] | [
14
] | 1 | [] | [] | 0 | true | Family | Phytoreovirus outer capsid P8 | Phytoreovirus outer capsid P8 | Phytoreo_P8 | 6 |
IPR009808 | 9,808 | Protein of unknown function, DUF1378 | DUF1378 | Family | 216 | false | false | This family consists of hypothetical bacterial and phage proteins of around 59 residues in length. Bacterial members of this family seem to be specific to Enterobacteria. The function of this family is unknown. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF07125"
] | [
"DUF1378"
] | [
216
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Pseudomonadati",
"Viruses"
] | [
157,
59
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function, DUF1378 | Protein of unknown function, DUF1378 | DUF1378 | 4 |
IPR009809 | 9,809 | Cell division protein ZapC | ZapC | Family | 1,785 | false | false | ZapC (Z-associated protein C) contributes to the efficiency of the cell division process by in maintaining FtsZ ring stability during cell division [ , ]. It consists of a N-terminal α/β domain which contains a pocket, termed the N-domain pocket, lined with residues important for ZapC function as an FtsZ bundler and a ... | [] | [] | [] | 0 | [
"HAMAP",
"PIRSF"
] | [
"MF_00906",
"PIRSF010252"
] | [
"ZapC",
"ZapC"
] | [
1722,
1763
] | 2 | [] | [] | [] | 0 | [
"5e1l",
"5fo3"
] | 2 | [
"PUB00060666",
"PUB00060667",
"PUB00101038",
"PUB00101039"
] | [
"21216997",
"21216995",
"26655719",
"26619764"
] | [
"Identification of Escherichia coli ZapC (YcbW) as a component of the division apparatus that binds and bundles FtsZ polymers.",
"Identification and characterization of ZapC, a stabilizer of the FtsZ ring in Escherichia coli.",
"Structural and Functional Analyses Reveal Insights into the Molecular Properties of... | [
2011,
2011,
2016,
2015
] | 4 | [] | [] | 0 | 0 | null | [
"Bacteria",
"marine sediment metagenome"
] | [
1784,
1
] | 2 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Cell division protein ZapC | Cell division protein ZapC | ZapC | 9 |
IPR009810 | 9,810 | Late nodulin domain | Nodulin_late_dom | Domain | 1,410 | false | false | This entry represents a domain found in a group of plant proteins, including late nodulin sequences which are homologous to the Pisum sativum (Garden pea) ENOD3 protein. ENOD3 is expressed in the late stages of root nodule formation and contains two pairs of cysteine residues toward the proteins C terminus which may be... | [
"GO:0046872"
] | [
"metal ion binding"
] | [
"molecular_function"
] | 1 | [
"PFAM"
] | [
"PF07127"
] | [
"Nodulin_late"
] | [
1410
] | 1 | [] | [] | [] | 0 | [
"7th8",
"8ulm"
] | 2 | [
"PUB00013009"
] | [
"2152123"
] | [
"Sequential induction of nodulin gene expression in the developing pea nodule."
] | [
1990
] | 1 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
1410
] | 1 | [
"Arabidopsis thaliana"
] | [
2
] | 1 | true | Domain | Late nodulin domain | Late nodulin domain | Nodulin_late_dom | 1 |
IPR009811 | 9,811 | Protein of unknown function DUF1380 | DUF1380 | Family | 1,285 | false | false | This family consists of several hypothetical bacterial proteins of around 140 residues in length. Members of this family seem to be specific to Enterobacteria. The function of this family is unknown. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF07128"
] | [
"DUF1380"
] | [
1285
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Clonorchis sinensis",
"human gut metagenome"
] | [
1283,
1,
1
] | 3 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Protein of unknown function DUF1380 | Protein of unknown function DUF1380 | DUF1380 | 1 |
IPR009812 | 9,812 | Protein of unknown function DUF1381 | DUF1381 | Family | 290 | false | false | This family consists of several hypothetical Staphylococcus and bacteriophage proteins of around 65 residues in length. The function of this family is unknown. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF07129"
] | [
"DUF1381"
] | [
290
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Viruses"
] | [
171,
119
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function DUF1381 | Protein of unknown function DUF1381 | DUF1381 | 2 |
IPR009813 | 9,813 | Uncharacterised protein family YebG | YebG | Family | 2,761 | false | false | This family consists of several bacterial YebG proteins. YebG is a DNA damage-inducible protein belonging to the SOS regulon in Escherichia coli. Its expression is regulated by LexA and RecA and is induced following DNA damage, such as that caused by mitomycin C treatment [ ]. Additionally, induction of the yebG gene o... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF07130"
] | [
"YebG"
] | [
2761
] | 1 | [] | [] | [] | 0 | [
"3erm"
] | 1 | [
"PUB00013010",
"PUB00163238"
] | [
"10474193",
"9368369"
] | [
"Identification of genetic factors altering the SOS induction of DNA damage-inducible yebG gene in Escherichia coli.",
"Identification of yebG as a DNA damage-inducible Escherichia coli gene."
] | [
1999,
1997
] | 2 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Opisthokonta",
"metagenomes"
] | [
2751,
2,
8
] | 3 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Uncharacterised protein family YebG | Uncharacterised protein family YebG | YebG | 7 |
IPR009814 | 9,814 | Bacteriophage lambda, Xis (Q38267) | Phage_lambda_Xis_Q38267 | Family | 386 | false | false | This entry is represented by Bacteriophage lambda, Xis. This entry overlaps with IPR009750, both representing lambda Xis. The characteristics of the protein distribution suggest prophage matches in addition to the phage matches. This family consists of several hypothetical Escherichia coli and Bacteriophage lambda-like... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF07131"
] | [
"DUF1382"
] | [
386
] | 1 | [] | [] | [] | 0 | [
"8dsb"
] | 1 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Viruses",
"metagenomes"
] | [
295,
89,
2
] | 3 | [] | [] | 0 | true | Family | Bacteriophage lambda, Xis (Q38267) | Bacteriophage lambda, Xis (Q38267) | Phage_lambda_Xis_Q38267 | 9 |
IPR009815 | 9,815 | Baculovirus protein AC11 | AcMNPV_AC11 | Family | 66 | false | false | This family of baculovirus proteins is represented by Autographa californica nuclear polyhedrosis virus (AcMNPV) protein AC11 (Orf11). ac11 is an early gene essential for budded-virus production and occlusion-derived-virus envelopment [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF07138"
] | [
"AcMNPV_AC11"
] | [
66
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00082613"
] | [
"25320313"
] | [
"Autographa californica multiple nucleopolyhedrovirus ORF11 is essential for budded-virus production and occlusion-derived-virus envelopment."
] | [
2015
] | 1 | [] | [] | 0 | 0 | null | [
"Baculoviridae"
] | [
66
] | 1 | [] | [] | 0 | true | Family | Baculovirus protein AC11 | Baculovirus protein AC11 | AcMNPV_AC11 | 6 |
IPR009818 | 9,818 | PAM2 motif | PAM2_motif | Conserved_site | 15,065 | false | false | The PABP-interacting motif PAM2 has been identified in various eukaryotic proteins as an important binding site for . It has been found in a wide range of eukaryotic proteins [ , , ]. Strikingly, this motif appears to occur solely outside of globular domains [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF07145"
] | [
"PAM2"
] | [
15065
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-HSA-429947",
"R-HSA-5656169",
"R-HSA-5689880",
"R-HSA-72764",
"R-HSA-9010553",
"R-HSA-975956",
"R-HSA-975957",
"R-HSA-9820841",
"R-HSA-9820865",
"R-MMU-429947",
"R-MMU-5656169",
"R-MMU-5689880",
"R-MMU-72764",
"R-MMU-975956",
"R-MMU-975957",
"R-RNO-5656169",
"R-RNO-5689880"
] | [
"REACTOME:R-HSA-429947",
"REACTOME:R-HSA-5656169",
"REACTOME:R-HSA-5689880",
"REACTOME:R-HSA-72764",
"REACTOME:R-HSA-9010553",
"REACTOME:R-HSA-975956",
"REACTOME:R-HSA-975957",
"REACTOME:R-HSA-9820841",
"REACTOME:R-HSA-9820865",
"REACTOME:R-MMU-429947",
"REACTOME:R-MMU-5656169",
"REACTOME:R-MM... | 17 | [
"1jgn",
"1jh4",
"2rqg",
"3ktr",
"3kui",
"3kuj",
"3kus",
"3kut",
"3ntw",
"5lzt",
"8s6u"
] | 11 | [
"PUB00012812",
"PUB00012813",
"PUB00012814",
"PUB00019987",
"PUB00026383",
"PUB00077680",
"PUB00077681",
"PUB00090910",
"PUB00103331",
"PUB00151918"
] | [
"9339681",
"12812977",
"9462862",
"15003521",
"14685257",
"18602463",
"8896555",
"11172725",
"26224628",
"20740007"
] | [
"The expansion of the CAG repeat in ataxin-2 is a frequent cause of autosomal dominant spinocerebellar ataxia.",
"Expansion of the polyQ repeat in ataxin-2 alters its Golgi localization, disrupts the Golgi complex and causes cell death.",
"Ataxin-2, global regulators of bacterial gene expression, and spliceosom... | [
1997,
2003,
1998,
2004,
2004,
2008,
1996,
2001,
2015,
2010
] | 10 | [] | [] | 0 | 0 | null | [
"Eukaryota",
"Pseudomonadati",
"viral metagenome"
] | [
15056,
8,
1
] | 3 | [
"Arabidopsis thaliana",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Schizosaccharomyces pombe (strain 972 / ATCC 24843)",
"Ze... | [
47,
39,
10,
35,
32,
1,
29,
41,
1,
110
] | 10 | true | Conserved_site | PAM2 motif | PAM2 motif | PAM2_motif | 1 |
IPR009819 | 9,819 | Pes-10 | Pes-10 | Family | 58 | false | false | This family consists of several Caenorhabditis elegans pes-10 and related proteins. Members of this family are typically around 400 residues in length. The function of this family is unknown. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF07149"
] | [
"Pes-10"
] | [
58
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
58
] | 1 | [
"Caenorhabditis elegans"
] | [
6
] | 1 | true | Family | Pes-10 | Pes-10 | Pes-10 | 8 |
IPR009820 | 9,820 | Protein of unknown function DUF1390 | DUF1390 | Family | 64 | false | false | This family consists of several Paramecium bursaria chlorella virus 1 (PBCV-1) proteins of around 250 residues in length. The function of this family is unknown. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF07150"
] | [
"DUF1390"
] | [
64
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Chlorovirus"
] | [
64
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF1390 | Protein of unknown function DUF1390 | DUF1390 | 7 |
IPR009821 | 9,821 | Protein of unknown function DUF1391 | DUF1391 | Family | 503 | false | false | This family consists of several Enterobacterial proteins of around 50 residues in length. Members of this family are found in Escherichia coli and Salmonella typhi where they are often known as YdfA. The function of this family is unknown. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF07151"
] | [
"DUF1391"
] | [
503
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Caudoviricetes",
"Pseudomonadati",
"human gut metagenome"
] | [
3,
499,
1
] | 3 | [
"Escherichia coli (strain K12)"
] | [
2
] | 1 | true | Family | Protein of unknown function DUF1391 | Protein of unknown function DUF1391 | DUF1391 | 3 |
IPR009822 | 9,822 | YaeQ | YaeQ | Family | 5,875 | false | false | This family consists of several hypothetical bacterial proteins of around 180 residues in length, which are often known as YaeQ. YaeQ is homologous to RfaH, a specialised transcription elongation protein and YaeQ is known to compensate for loss of RfaH function [ ]. However, YaeQ does not appear to affect transcription... | [] | [] | [] | 0 | [
"PFAM",
"PIRSF",
"SMART"
] | [
"PF07152",
"PIRSF011484",
"SM01322"
] | [
"YaeQ",
"YaeQ",
"YaeQ"
] | [
5875,
5566,
5846
] | 3 | [] | [] | [] | 0 | [
"2g3w",
"2ot9",
"3c0u",
"7tcb"
] | 4 | [
"PUB00013018",
"PUB00047490",
"PUB00056830"
] | [
"9604894",
"17623842",
"15503145"
] | [
"A gene, yaeQ, that suppresses reduced operon expression caused by mutations in the transcription elongation gene rfaH in Escherichia coli and Salmonella typhimurium.",
"Structure of Xanthomonas axonopodis pv. citri YaeQ reveals a new compact protein fold built around a variation of the PD-(D/E)XK nuclease motif.... | [
1998,
2007,
2004
] | 3 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"metagenomes"
] | [
5815,
7,
53
] | 3 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | YaeQ | YaeQ | YaeQ | 6 |
IPR009823 | 9,823 | Herpesvirus SORF3 | Herpes_SORF3 | Family | 30 | false | false | This family consists of several SORF3 proteins from the Marek's disease-like viruses (Meleagrid herpesvirus 1, also known as Gallid herpesvirus 2) and other Herpesvirus. Members of this family are around 350 residues in length. The function of this family is unknown. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF07153"
] | [
"Marek_SORF3"
] | [
30
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Alphaherpesvirinae"
] | [
30
] | 1 | [] | [] | 0 | true | Family | Herpesvirus SORF3 | Herpesvirus SORF3 | Herpes_SORF3 | 8 |
IPR009824 | 9,824 | Protein of unknown function DUF1392 | DUF1392 | Family | 203 | false | false | This family consists of several hypothetical cyanobacterial proteins of around 150 residues in length. The function of this family is unknown. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF07154"
] | [
"DUF1392"
] | [
203
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Nostocales"
] | [
203
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF1392 | Protein of unknown function DUF1392 | DUF1392 | 7 |
IPR009825 | 9,825 | ECF transporter, substrate-specific component-like | ECF_substrate-spec-like | Family | 7,827 | false | false | This family consists of several bacterial proteins of around 180 residues in length that appear to be multi-pass membrane proteins. Many family members are functionally uncharacterised. Others appear to be substrate specific components of an energy-coupling factor (ECF) type transport system, such as Thiamine precursor... | [
"GO:0016020"
] | [
"membrane"
] | [
"cellular_component"
] | 1 | [
"PFAM"
] | [
"PF07155"
] | [
"ECF-ribofla_trS"
] | [
7827
] | 1 | [
"GP"
] | [
"GenProp1094"
] | [
"GP:GenProp1094"
] | 1 | [
"4hzu"
] | 1 | [
"PUB00056838"
] | [
"21135102"
] | [
"Quaternary structure and functional unit of energy coupling factor (ECF)-type transporters."
] | [
2011
] | 1 | [] | [
"IPR022914",
"IPR023812"
] | 0 | 2 | 0 | [
"Archaea",
"Bacteria",
"Inoviridae sp. ctO6A5",
"Rhizophagus irregularis",
"unclassified sequences"
] | [
174,
7535,
1,
1,
116
] | 5 | [] | [] | 0 | true | Family | ECF transporter, substrate-specific component-like | ECF transporter, substrate-specific component-like | ECF_substrate-spec-like | 9 |
IPR009827 | 9,827 | Dicarboxylate carrier MatC N-terminal | MatC_N | Domain | 2,695 | false | false | This entry represents the N-terminal region of the bacterial dicarboxylate carrier protein MatC. The MatC protein is an integral membrane protein that could function as a malonate carrier [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF07158"
] | [
"MatC_N"
] | [
2695
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00013021"
] | [
"9826185"
] | [
"A gene cluster encoding malonyl-CoA decarboxylase (MatA), malonyl-CoA synthetase (MatB) and a putative dicarboxylate carrier protein (MatC) in Rhizobium trifolii--cloning, sequencing, and expression of the enzymes in Escherichia coli."
] | [
1998
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Knufia peltigerae",
"metagenomes"
] | [
2685,
1,
9
] | 3 | [] | [] | 0 | true | Domain | Dicarboxylate carrier MatC N-terminal | Dicarboxylate carrier MatC N-terminal | MatC_N | 8 |
IPR009828 | 9,828 | CYRIA/CYRIB, Rac1 binding domain | CYRIA/CYRIB_Rac1-bd | Domain | 8,863 | false | false | This domain has been annotated as Rac1-binding domain [ , ]. It can be found in human CYRIA/CYRIB and at the N terminus of CYFIP1/2 [ ]. CYFIP proteins are known RAC1 effectors that stimulate actin polymerization [ ]. CYRIA/B are also localised to early macropinosomes and act to modulate their formation by regulating R... | [
"GO:0031267"
] | [
"small GTPase binding"
] | [
"molecular_function"
] | 1 | [
"PFAM"
] | [
"PF07159"
] | [
"CYRIA-B_Rac1-bd"
] | [
8863
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOM... | [
"R-BTA-114608",
"R-CEL-2029482",
"R-CEL-5663213",
"R-CEL-6798695",
"R-CEL-9013149",
"R-CEL-9013404",
"R-CEL-9013408",
"R-CEL-9013423",
"R-DDI-114608",
"R-DDI-2029482",
"R-DDI-5663213",
"R-DDI-6798695",
"R-DDI-9013149",
"R-DDI-9013404",
"R-DDI-9013408",
"R-DDI-9013423",
"R-DME-2029482... | [
"REACTOME:R-BTA-114608",
"REACTOME:R-CEL-2029482",
"REACTOME:R-CEL-5663213",
"REACTOME:R-CEL-6798695",
"REACTOME:R-CEL-9013149",
"REACTOME:R-CEL-9013404",
"REACTOME:R-CEL-9013408",
"REACTOME:R-CEL-9013423",
"REACTOME:R-DDI-114608",
"REACTOME:R-DDI-2029482",
"REACTOME:R-DDI-5663213",
"REACTOME:... | 45 | [
"3p8c",
"4n78",
"6yjj",
"6yjk",
"7ajk",
"7ajl",
"7usc",
"7usd",
"7use"
] | 9 | [
"PUB00093955",
"PUB00093956",
"PUB00093957",
"PUB00100503"
] | [
"30250061",
"31413787",
"31285585",
"34165494"
] | [
"Fam49/CYRI interacts with Rac1 and locally suppresses protrusions.",
"CYRI/ Fam49 Proteins Represent a New Class of Rac1 Interactors.",
"CYRI/FAM49B negatively regulates RAC1-driven cytoskeletal remodelling and protects against bacterial infection.",
"CYRI-A limits invasive migration through macropinosome fo... | [
2018,
2019,
2019,
2021
] | 4 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
8863
] | 1 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Zea mays"
] | [
6,
2,
30,
3,
32,
12,
2,
13,
4
] | 9 | true | Domain | CYRIA/CYRIB, Rac1 binding domain | CYRIA/CYRIB, Rac1 binding domain | CYRIA/CYRIB_Rac1-bd | 4 |
IPR009829 | 9,829 | Spindle and kinetochore-associated protein 1 | SKA1 | Family | 2,070 | false | false | Spindle and kinetochore-associated protein 1 (SKA1, also known as SKA complex subunit 1) is a component of the SKA1 complex (consists of Ska1, Ska2, and Ska3/Rama1), a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation [ ]. It is required for timely anaphase onse... | [
"GO:0008017",
"GO:0007059",
"GO:0051301"
] | [
"microtubule binding",
"chromosome segregation",
"cell division"
] | [
"molecular_function",
"biological_process",
"biological_process"
] | 3 | [
"PFAM",
"PANTHER"
] | [
"PF07160",
"PTHR28573"
] | [
"SKA1",
""
] | [
2061,
1940
] | 2 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOM... | [
"R-HSA-141444",
"R-HSA-2467813",
"R-HSA-2500257",
"R-HSA-5663220",
"R-HSA-68877",
"R-HSA-9648025",
"R-MMU-141444",
"R-MMU-2467813",
"R-MMU-2500257",
"R-MMU-5663220",
"R-MMU-68877",
"R-MMU-9648025",
"R-RNO-141444",
"R-RNO-2467813",
"R-RNO-2500257",
"R-RNO-5663220",
"R-RNO-68877",
"R... | [
"REACTOME:R-HSA-141444",
"REACTOME:R-HSA-2467813",
"REACTOME:R-HSA-2500257",
"REACTOME:R-HSA-5663220",
"REACTOME:R-HSA-68877",
"REACTOME:R-HSA-9648025",
"REACTOME:R-MMU-141444",
"REACTOME:R-MMU-2467813",
"REACTOME:R-MMU-2500257",
"REACTOME:R-MMU-5663220",
"REACTOME:R-MMU-68877",
"REACTOME:R-MM... | 24 | [
"2lyc",
"4aj5",
"4c9y",
"4ca0"
] | 4 | [
"PUB00061771",
"PUB00061805",
"PUB00077600"
] | [
"17093495",
"22483620",
"24413531"
] | [
"Timely anaphase onset requires a novel spindle and kinetochore complex comprising Ska1 and Ska2.",
"Structural and functional organization of the Ska complex, a key component of the kinetochore-microtubule interface.",
"Structural basis for microtubule recognition by the human kinetochore Ska complex."
] | [
2006,
2012,
2014
] | 3 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
2070
] | 1 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Homo sapiens",
"Mus musculus",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Zea mays"
] | [
8,
1,
2,
3,
2,
1,
4,
6
] | 8 | true | Family | Spindle and kinetochore-associated protein 1 | Spindle and kinetochore-associated protein 1 | SKA1 | 2 |
IPR009830 | 9,830 | LppX/LprAFG lipoprotein family | LppX/LprAFG | Family | 2,009 | false | false | This entry consists of several lipoproteins mainly from Mycobacterium species, collectively known as the LppX/LprAFG family. Proteins in this entry include: LprG ( ) from Mycobacterium tuberculosis: an immunogenic 27kDa membrane-associated lipoprotein [ ]. Expression of the LprG protein is essential for the growth of M... | [] | [] | [] | 0 | [
"PFAM",
"CDD"
] | [
"PF07161",
"cd16334"
] | [
"LppX_LprAFG",
"LppX-like"
] | [
2009,
1597
] | 2 | [
"REACTOME"
] | [
"R-HSA-9636383"
] | [
"REACTOME:R-HSA-9636383"
] | 1 | [
"2byo",
"3mh8",
"3mh9",
"3mha",
"4qa8",
"4zra"
] | 6 | [
"PUB00020730",
"PUB00020731",
"PUB00020732",
"PUB00020734",
"PUB00039808",
"PUB00076900"
] | [
"9387238",
"14998516",
"15294983",
"12581360",
"16541102",
"16785538"
] | [
"A novel 27 kDa lipoprotein antigen from Mycobacterium bovis.",
"The knockout of the lprG-Rv1410 operon produces strong attenuation of Mycobacterium tuberculosis.",
"Mycobacterium tuberculosis LprG (Rv1411c): a novel TLR-2 ligand that inhibits human macrophage class II MHC antigen processing.",
"Interaction o... | [
1997,
2004,
2004,
2003,
2006,
2006
] | 6 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Rhynchospora breviuscula",
"metagenomes"
] | [
1993,
1,
15
] | 3 | [] | [] | 0 | true | Family | LppX/LprAFG lipoprotein family | LppX/LprAFG lipoprotein family | LppX/LprAFG | 3 |
IPR009832 | 9,832 | Protein of unknown function DUF1397 | DUF1397 | Family | 1,168 | false | false | This entry consists of several insect specific 27kDa Haemolymph glycoprotein precursors. The function of this family is unknown [ ]. | [] | [] | [] | 0 | [
"PFAM",
"PANTHER"
] | [
"PF07165",
"PTHR20997"
] | [
"DUF1397",
""
] | [
1167,
967
] | 2 | [] | [] | [] | 0 | [] | 0 | [
"PUB00013024"
] | [
"7742978"
] | [
"Isolation, cloning and deduced amino acid sequence of a novel glycoprotein from the haemolymph of the hawkmoth Manduca sexta."
] | [
1995
] | 1 | [] | [] | 0 | 0 | null | [
"Actinomycetes",
"Protostomia"
] | [
2,
1166
] | 2 | [
"Drosophila melanogaster"
] | [
11
] | 1 | true | Family | Protein of unknown function DUF1397 | Protein of unknown function DUF1397 | DUF1397 | 7 |
IPR009833 | 9,833 | Uncharacterised protein DUF1398 | DUF1398 | Family | 2,173 | false | false | This family consists of several hypothetical bacterial proteins of around 130 residues in length. The function of this family is unknown. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF07166"
] | [
"DUF1398"
] | [
2173
] | 1 | [] | [] | [] | 0 | [
"2hh8"
] | 1 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Caudoviricetes",
"Eukaryota",
"metagenomes"
] | [
2130,
6,
31,
6
] | 4 | [
"Escherichia coli (strain K12)"
] | [
3
] | 1 | true | Family | Uncharacterised protein DUF1398 | Uncharacterised protein DUF1398 | DUF1398 | 2 |
IPR009834 | 9,834 | Ureide permease | Ureide_permease | Family | 2,369 | false | false | This entry represents Ureide permease 1-5 from Arabidopsis thaliana and similar proteins from plants and bacteria. UPS transports a wide spectrum of oxo derivatives of heterocyclic nitrogen compounds, including allantoin, uric acid and xanthine, but not adenine. Transport is dependent on glucose and a proton gradient [... | [
"GO:0071705",
"GO:0016020"
] | [
"nitrogen compound transport",
"membrane"
] | [
"biological_process",
"cellular_component"
] | 2 | [
"PFAM"
] | [
"PF07168"
] | [
"Ureide_permease"
] | [
2369
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00053931",
"PUB00071885",
"PUB00071886",
"PUB00100036",
"PUB00100037"
] | [
"11971139",
"15308648",
"16738859",
"27209043",
"31862838"
] | [
"A novel superfamily of transporters for allantoin and other oxo derivatives of nitrogen heterocyclic compounds in Arabidopsis.",
"UPS1 and UPS2 from Arabidopsis mediate high affinity transport of uracil and 5-fluorouracil.",
"Comparative studies on Ureide Permeases in Arabidopsis thaliana and analysis of two a... | [
2002,
2004,
2006,
2016,
2020
] | 5 | [] | [
"IPR030189"
] | 0 | 1 | 0 | [
"Bacteria",
"Eukaryota",
"metagenomes"
] | [
553,
1792,
24
] | 3 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
33,
17,
24
] | 3 | true | Family | Ureide permease | Ureide permease | Ureide_permease | 7 |
IPR009835 | 9,835 | Sortase B family | SrtB | Family | 3,805 | false | false | Members of this transpeptidase family are, in most cases, designated sortase B, product of the srtB gene. This protein shows only distant similarity to the sortase A family, for which there may be several members in a single bacterial genome. Typical SrtB substrate motifs include NAKTN, NPKSS, etc, and otherwise resemb... | [] | [] | [] | 0 | [
"NCBIFAM",
"CDD"
] | [
"TIGR03064",
"cd05826"
] | [
"sortase_srtB",
"Sortase_B"
] | [
2578,
3805
] | 2 | [
"GP"
] | [
"GenProp0664"
] | [
"GP:GenProp0664"
] | 1 | [
"1ng5",
"1qwz",
"1qx6",
"1qxa",
"1rz2",
"2oqw",
"2oqz",
"3psq",
"4lfd",
"4ux7",
"4y4q",
"5b23",
"5gyj",
"5jcv",
"5yfk",
"6kyc",
"6kyd"
] | 17 | [
"PUB00014494",
"PUB00029054",
"PUB00030423",
"PUB00045370",
"PUB00081158",
"PUB00081159",
"PUB00081160",
"PUB00081162",
"PUB00081163",
"PUB00081164"
] | [
"11401711",
"15242591",
"14725770",
"17012401",
"15718231",
"16524923",
"15808931",
"17200112",
"16041044",
"15028680"
] | [
"Sortase-catalysed anchoring of surface proteins to the cell wall of Staphylococcus aureus.",
"Structures of sortase B from Staphylococcus aureus and Bacillus anthracis reveal catalytic amino acid triad in the active site.",
"The structure of sortase B, a cysteine transpeptidase that tethers surface protein to ... | [
2001,
2004,
2004,
2006,
2005,
2006,
2005,
2007,
2005,
2004
] | 10 | [
"IPR005754"
] | [
"IPR015986"
] | 1 | 1 | 0 | [
"Bacteria",
"Hemiptera",
"Siphoviridae sp. ctHip2",
"metagenomes"
] | [
3763,
2,
1,
39
] | 4 | [] | [] | 0 | true | Family | Sortase B family | Sortase B family | SrtB | 4 |
IPR009836 | 9,836 | GRDP1/2 domain | GRDP1/2_dom | Domain | 6,503 | false | false | This entry represents a domain found towards the N-terminal end of Arabidopsis Glycine-rich domain-containing protein 1 and 2 (GRDP1/2) and in similar eukaryotic proteins. Glycine-rich domain-containing proteins (GRDPs) play a regulatory role in abscisic acid (ABA) signalling and tolerance to abiotic stress during germ... | [] | [] | [] | 0 | [
"PFAM",
"PANTHER"
] | [
"PF07173",
"PTHR34365"
] | [
"GRDP-like",
""
] | [
5857,
6322
] | 2 | [] | [] | [] | 0 | [] | 0 | [
"PUB00077560",
"PUB00096853",
"PUB00160499"
] | [
"25653657",
"28285133",
"29568308"
] | [
"Overexpression of AtGRDP2, a novel glycine-rich domain protein, accelerates plant growth and improves stress tolerance.",
"Modification of AtGRDP1 gene expression affects silique and seed development in Arabidopsis thaliana.",
"Plant Glycine-Rich Proteins in Stress Response: An Emerging, Still Prospective Stor... | [
2014,
2017,
2018
] | 3 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Megaviricetes",
"ecological metagenomes"
] | [
215,
6277,
3,
8
] | 4 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
24,
2,
1,
6,
22
] | 5 | true | Domain | GRDP1/2 domain | GRDP1/2 domain | GRDP1/2_dom | 1 |
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