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Does Knockout of Snx21 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,264
Knockout
Snx21
cell proliferation
Colonic Cancer Cell Line
Gene: Snx21 (sorting nexin family member 21) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, protein transport; MF: lipid binding, molecular_function, phosphatidylinositol binding, phosphatidylinositol phosphate binding, phosphatidylinositol-3-phosphat...
Does Knockout of Atpaf2 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,262
Knockout
Atpaf2
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Atpaf2 (ATP synthase mitochondrial F1 complex assembly factor 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial proton-transporting ATP synthase complex assembly, proton-transporting ATP synthase complex assembly; CC: cytosol, membrane, mitochondrial ...
Does Knockout of Flad1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Flad1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Flad1 (flavin adenine dinucleotide synthetase 1) Type: protein-coding Summary: Enables FMN adenylyltransferase activity. Involved in flavin adenine dinucleotide biosynthetic process and riboflavin metabolic process. Is active in cytosol. Orthologous to human FLAD1 (flavin adenine dinucleotide synt...
Does Knockout of Fbf1 in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
Fbf1
response to virus
Embryonic Fibroblast Cell Line
Gene: Fbf1 (Fas binding factor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apical junction assembly, cell projection organization, cilium assembly, establishment of epithelial cell polarity; CC: anchoring junction, apical junction complex, centriole, centrosome, ci...
Does Knockout of Hmga2 in Lymphoma Cell Line causally result in response to chemicals?
0
1,532
Knockout
Hmga2
response to chemicals
Lymphoma Cell Line
Gene: Hmga2 (high mobility group AT-hook 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: adipose tissue development, adrenal gland development, base-excision repair, cell division, cell proliferation in forebrain, chondrocyte differentiation, chondrocyte proliferation,...
Does Knockout of Tas2r125 in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Tas2r125
response to chemicals
Pancreatic Cancer Cell Line
Gene: Tas2r125 (taste receptor, type 2, member 125) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, detection of chemical stimulus involved in sensory perception of bitter taste, detection of chemical stimulus involved in sens...
Does Knockout of H2-M10.6 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,290
Knockout
H2-M10.6
cell proliferation
Mouse kidney carcinoma cell
Gene: H2-M10.6 (histocompatibility 2, M region locus 10.6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent, antigen processing and presentation of endogenous ...
Does Knockout of Csk in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,262
Knockout
Csk
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Csk (c-src tyrosine kinase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: adaptive immune response, adherens junction organization, cellular response to peptide hormone stimulus, immune system process, intracellular signal transduction, negative regulation of ERK1...
Does Knockout of Fhdc1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Fhdc1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Fhdc1 (FH2 domain containing 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Golgi ribbon formation, actin filament polymerization, cell projection organization, cilium assembly, stress fiber assembly; MF: actin binding, microtubule binding, protein binding; CC: ...
Does Knockout of Zfp474 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Zfp474
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Zfp474 (zinc finger protein 474) Type: protein-coding Summary: No summary available. Gene Ontology: MF: metal ion binding, molecular_function, zinc ion binding Pathways: UniProt: Q6V5K9 Entrez ID: 66758
Does Knockout of Fntb in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Fntb
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Fntb (farnesyltransferase, CAAX box, beta) Type: protein-coding Summary: No summary available. Gene Ontology: BP: lipid metabolic process, negative regulation of cell population proliferation, positive regulation of cell cycle, positive regulation of cell population proliferation, positiv...
Does Knockout of Frmd3 in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Frmd3
cell viability
Immortal mouse chromaffin cells
Gene: Frmd3 (FERM domain containing 3) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cytoskeleton, membrane Pathways: UniProt: Q8BHD4 Entrez ID: 242506
Does Knockout of L3hypdh in Embryonic Stem Cell Line causally result in cell proliferation?
0
578
Knockout
L3hypdh
cell proliferation
Embryonic Stem Cell Line
Gene: L3hypdh (L-3-hydroxyproline dehydratase (trans-)) Type: protein-coding Summary: No summary available. Gene Ontology: MF: hydro-lyase activity, lyase activity, proline racemase activity, trans-L-3-hydroxyproline dehydratase activity Pathways: Arginine and proline metabolism - Mus ...
Does Knockout of Aplp1 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,265
Knockout
Aplp1
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Aplp1 (amyloid beta precursor like protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: animal organ development, apoptotic process, axonogenesis, cell adhesion, cellular response to norepinephrine stimulus, central nervous system development, cytosolic mRNA p...
Does Knockout of Glis1 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,273
Knockout
Glis1
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Glis1 (GLIS family zinc finger 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, fat cell differentiation, negative regulation of cell fate commitment, negative regulation of transcription by RNA polymerase II, osteoblast differentiation, posi...
Does Knockout of Ptpmt1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Ptpmt1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Ptpmt1 (protein tyrosine phosphatase, mitochondrial 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cardiolipin biosynthetic process, lipid metabolic process, negative regulation of insulin secretion involved in cellular response to glucose stimulus, phosphatidyl...
Does Knockout of Gata3 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,440
Knockout
Gata3
protein/peptide accumulation
Embryonic Cell Line
Gene: Gata3 (GATA binding protein 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: T cell differentiation, T cell differentiation in thymus, T cell receptor signaling pathway, T-helper 2 cell differentiation, TOR signaling, anatomical structure formation involved in mor...
Does Knockout of Krtap7-1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
82
Knockout
Krtap7-1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Krtap7-1 (keratin associated protein 7-1) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cellular_component, intermediate filament Pathways: UniProt: Q9D3I6 Entrez ID: 71363
Does Knockout of Pgap1 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
2,307
Knockout
Pgap1
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Pgap1 (post-GPI attachment to proteins 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: GPI anchor biosynthetic process, anterior/posterior axis specification, embryonic pattern specification, forebrain regionalization, head development, positive regulation of ER ...
Does Knockout of Poc1a in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,262
Knockout
Poc1a
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Poc1a (POC1 centriolar protein A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: bone development, cell projection organization, cilium assembly, growth plate cartilage chondrocyte development, mitotic spindle organization, non-motile cilium assembly, positive regu...
Does Knockout of Oxsr1 in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Oxsr1
cell proliferation
Colonic Cancer Cell Line
Gene: Oxsr1 (oxidative-stress responsive 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell volume homeostasis, cellular hyperosmotic response, cellular hypotonic response, cellular response to chemokine, chemokine (C-C motif) ligand 21 signaling pathway, chemokine (...
Does Knockout of Fam32a in Embryonic Stem Cell Line causally result in cell proliferation?
1
579
Knockout
Fam32a
cell proliferation
Embryonic Stem Cell Line
Gene: Fam32a (family with sequence similarity 32, member A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, biological_process; CC: nucleolus, nucleoplasm, nucleus Pathways: Metabolism of RNA, Processing of Capped Intron-Containing Pre-mRNA, mR...
Does Knockout of Nlrp1a in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
81
Knockout
Nlrp1a
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Nlrp1a (NLR family, pyrin domain containing 1A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: NLRP1 inflammasome complex assembly, activation of innate immune response, antiviral innate immune response, cellular response to UV-B, defense response, defense response...
Does Knockout of Sult3a2 in Regulatory T cell causally result in cell proliferation?
0
2,127
Knockout
Sult3a2
cell proliferation
Regulatory T cell
Gene: Sult3a2 (sulfotransferase family 3A, member 2) Type: protein-coding Summary: No summary available. Gene Ontology: MF: sulfotransferase activity, transferase activity; CC: cytoplasm Pathways: UniProt: G5E904 Entrez ID: 215895
Does Knockout of Sae1 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
1
2,307
Knockout
Sae1
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Sae1 (SUMO1 activating enzyme subunit 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of protein sumoylation, protein sumoylation; MF: ATP-dependent protein binding, SUMO activating enzyme activity, ligase activity, protein heterodimerization ...
Does Knockout of Rhox8 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Rhox8
protein/peptide distribution
myoblast cell line
Gene: Rhox8 (reproductive homeobox 8) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of transcription by RNA polymerase II, regulation of gene expression, regulation of transcription by RNA polymerase II, spermatogenesis; MF: DNA binding, DNA-binding ...
Does Knockout of Prrt1 in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Prrt1
response to chemicals
Pancreatic Cancer Cell Line
Gene: Prrt1 (proline-rich transmembrane protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: intracellular protein localization, learning or memory, long-term synaptic depression, long-term synaptic potentiation, protein localization to cell surface, protein phospho...
Does Knockout of Faap100 in Lymphoma Cell Line causally result in response to chemicals?
1
1,537
Knockout
Faap100
response to chemicals
Lymphoma Cell Line
Gene: Faap100 (Fanconi anemia core complex associated protein 100) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, interstrand cross-link repair; MF: DNA binding, molecular_function; CC: Fanconi anaemia nuclear complex, chromatin, cytosol,...
Does Knockout of Insl3 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
161
Knockout
Insl3
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Insl3 (insulin-like 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway, in utero embryonic development, male gonad development, negative regulation of apoptotic process, negative regulation of...
Does Knockout of Cdc42 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Cdc42
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Cdc42 (cell division cycle 42) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Golgi organization, Rho protein signal transduction, actin cytoskeleton organization, actin filament branching, actin filament organization, adherens junction organization, anatomical str...
Does Knockout of Padi4 in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Padi4
cell proliferation
Melanoma Cell Line
Gene: Padi4 (peptidyl arginine deiminase, type IV) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chromatin organization, chromatin remodeling, immune system process, innate immune response, nucleosome assembly, post-translational protein modification, stem cell populati...
Does Knockout of Nde1 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,264
Knockout
Nde1
cell proliferation
Colonic Cancer Cell Line
Gene: Nde1 (nudE neurodevelopment protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, cell division, cell migration, centrosome duplication, centrosome localization, cerebral cortex development, chromosome localization, chromosome segregation,...
Does Knockout of Tmem165 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,265
Knockout
Tmem165
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Tmem165 (transmembrane protein 165) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Golgi calcium ion homeostasis, Golgi calcium ion transport, calcium ion transmembrane transport, calcium ion transport, intracellular calcium ion homeostasis, manganese ion transmemb...
Does Knockout of Rdh7 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Rdh7
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Rdh7 (retinol dehydrogenase 7) Type: protein-coding Summary: No summary available. Gene Ontology: BP: retinol metabolic process, steroid metabolic process; MF: all-trans-retinol dehydrogenase (NAD+) activity, androstan-3-alpha,17-beta-diol dehydrogenase (NAD+) activity, androsterone dehyd...
Does Knockout of Eif2ak2 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,174
Knockout
Eif2ak2
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Eif2ak2 (eukaryotic translation initiation factor 2-alpha kinase 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: antiviral innate immune response, cellular response to amino acid starvation, defense response to virus, endoplasmic reticulum unfolded protein respon...
Does Knockout of Tmed5 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
81
Knockout
Tmed5
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Tmed5 (transmembrane p24 trafficking protein 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Golgi ribbon formation, endoplasmic reticulum to Golgi vesicle-mediated transport, intracellular protein transport, protein transport; CC: COPII-coated ER to Golgi transp...
Does Knockout of Pgs1 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
1
2,172
Knockout
Pgs1
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Pgs1 (phosphatidylglycerophosphate synthase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cardiolipin biosynthetic process, diacylglycerol metabolic process, lipid metabolic process, phosphatidylglycerol biosynthetic process, phospholipid biosynthetic process; ...
Does Knockout of Rala in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Rala
cell proliferation
Embryonic Stem Cell Line
Gene: Rala (v-ral simian leukemia viral oncogene A (ras related)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Ras protein signal transduction, cell division, establishment of protein localization to mitochondrion, exocytosis, membrane raft localization, neural tube cl...
Does Knockout of Cd101 in Embryonic Stem Cell Line causally result in cell proliferation?
0
578
Knockout
Cd101
cell proliferation
Embryonic Stem Cell Line
Gene: Cd101 (CD101 antigen) Type: protein-coding Summary: No summary available. Gene Ontology: CC: membrane Pathways: Adaptive Immune System, Generation of second messenger molecules, Immune System, TCR signaling UniProt: A8E0Y8 Entrez ID: 630146
Does Knockout of Pdcd5 in Acute Myeloid Leukemia Cell Line causally result in cell proliferation?
1
684
Knockout
Pdcd5
cell proliferation
Acute Myeloid Leukemia Cell Line
Gene: Pdcd5 (programmed cell death 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, cellular response to transforming growth factor beta stimulus, negative regulation of protein folding, positive regulation of apoptotic process, positive regulation of...
Does Knockout of Fntb in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Fntb
cell proliferation
Melanoma Cell Line
Gene: Fntb (farnesyltransferase, CAAX box, beta) Type: protein-coding Summary: No summary available. Gene Ontology: BP: lipid metabolic process, negative regulation of cell population proliferation, positive regulation of cell cycle, positive regulation of cell population proliferation, positiv...
Does Knockout of Snrnp70 in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
Snrnp70
response to virus
Embryonic Fibroblast Cell Line
Gene: Snrnp70 (small nuclear ribonucleoprotein 70 (U1)) Type: protein-coding Summary: This gene encodes a subunit of the U1 snRNP (small nuclear ribonucleic particle), one of at least five snRNPs to comprise the spliceosome, which functions in processing of pre-mRNAs. The U1 snRNP has been shown to be i...
Does Knockout of Pus3 in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Pus3
cell proliferation
Melanoma Cell Line
Gene: Pus3 (pseudouridine synthase 3) Type: protein-coding Summary: Enables pseudouridine synthase activity. Acts upstream of or within tRNA pseudouridine synthesis. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; heart ventricle; pharyng...
Does Knockout of Ola1 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,267
Knockout
Ola1
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Ola1 (Obg-like ATPase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ATP metabolic process; MF: ATP binding, ATP hydrolysis activity, GTP binding, hydrolase activity, metal ion binding, nucleotide binding, ribosomal large subunit binding, ribosome binding; CC: c...
Does Knockout of Brd2 in Acute Myeloid Leukemia Cell Line causally result in cell proliferation?
1
684
Knockout
Brd2
cell proliferation
Acute Myeloid Leukemia Cell Line
Gene: Brd2 (bromodomain containing 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell surface receptor signaling pathway via JAK-STAT, chromatin looping, chromatin organization, chromatin remodeling, neural tube closure, nucleosome assembly, positive regulation of T-...
Does Knockout of Vasn in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,286
Knockout
Vasn
cell proliferation
Mouse kidney carcinoma cell
Gene: Vasn (vasorin) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to hypoxia, cellular response to redox state, negative regulation of epithelial to mesenchymal transition, negative regulation of transforming growth factor beta receptor signaling path...
Does Knockout of Dynlt1a in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
165
Knockout
Dynlt1a
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Dynlt1a (dynein light chain Tctex-type 1A) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: Immune System, Innate Immune System, Neutrophil degranulation, Salmonella infection - Mus musculus (mouse) UniProt: P51807 Entrez ID: 10031087...
Does Knockout of Ypel5 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Ypel5
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Ypel5 (yippee like 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, cell population proliferation; MF: metal ion binding, molecular_function; CC: centrosome, cytoplasm, cytoskeleton, midbody, mitotic spindle pole, nucleus, spindle pole, ubiquit...
Does Knockout of Zbtb8os in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,265
Knockout
Zbtb8os
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Zbtb8os (zinc finger and BTB domain containing 8 opposite strand) Type: protein-coding Summary: No summary available. Gene Ontology: BP: tRNA processing, tRNA splicing, via endonucleolytic cleavage and ligation; MF: metal ion binding, molecular_function; CC: tRNA-splicing ligase complex ...
Does Knockout of Slc17a8 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
1,130
Knockout
Slc17a8
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Slc17a8 (solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8) Type: protein-coding Summary: No summary available. Gene Ontology: BP: L-glutamate import, L-glutamate transmembrane transport, chloride transmembrane transport, chloride transport, cochlea d...
Does Knockout of Reg3d in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
83
Knockout
Reg3d
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Reg3d (regenerating islet-derived 3 delta) Type: protein-coding Summary: Predicted to enable oligosaccharide binding activity; peptidoglycan binding activity; and signaling receptor activity. Predicted to be involved in antimicrobial humoral immune response mediated by antimicrobial peptide; posit...
Does Knockout of Tmem145 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,290
Knockout
Tmem145
cell proliferation
Mouse kidney carcinoma cell
Gene: Tmem145 (transmembrane protein 145) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, biological_process, response to pheromone; CC: cellular_component, membrane Pathways: UniProt: Q8C4U2 Entrez ...
Does Knockout of Nfkbie in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,290
Knockout
Nfkbie
cell proliferation
Mouse kidney carcinoma cell
Gene: Nfkbie (nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon) Type: protein-coding Summary: No summary available. Gene Ontology: BP: D-serine transmembrane transport, negative regulation of DNA-templated transcription; MF: protein binding, protein sequeste...
Does Knockout of Zfp735 in macrophage causally result in phagocytosis?
0
1,888
Knockout
Zfp735
phagocytosis
macrophage
Gene: Zfp735 (zinc finger protein 735) Type: protein-coding Summary: No summary available. Gene Ontology: BP: regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II; MF: metal ion binding, zinc ion binding; CC: nucleus Pathways: Gene expression (Tra...
Does Knockout of Ncoa5 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
1
2,307
Knockout
Ncoa5
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Ncoa5 (nuclear receptor coactivator 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: glucose homeostasis, negative regulation of insulin receptor signaling pathway, regulation of signal transduction; CC: actin cytoskeleton, nucleoplasm, nucleus Pathways: ...
Does Knockout of Hmgn2 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,262
Knockout
Hmgn2
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Hmgn2 (high mobility group nucleosomal binding domain 2) Type: protein-coding Summary: Predicted to enable chromatin binding activity. Acts upstream of or within negative regulation of transcription by RNA polymerase II and regulation of development, heterochronic. Located in female germ cell nucl...
Does Knockout of N6amt1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
N6amt1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: N6amt1 (N-6 adenine-specific DNA methyltransferase 1 (putative)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: arsonoacetate metabolic process, chromatin organization, methylation, negative regulation of gene expression, epigenetic, peptidyl-glutamine methylation,...
Does Knockout of Ezh2 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
1,130
Knockout
Ezh2
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Ezh2 (enhancer of zeste 2 polycomb repressive complex 2 subunit) Type: protein-coding Summary: No summary available. Gene Ontology: BP: B cell differentiation, DNA methylation-dependent constitutive heterochromatin formation, G1 to G0 transition, cardiac muscle hypertrophy in response to ...
Does Knockout of Otof in myoblast cell line causally result in protein/peptide distribution?
0
1,679
Knockout
Otof
protein/peptide distribution
myoblast cell line
Gene: Otof (otoferlin) Type: protein-coding Summary: Enables AP-2 adaptor complex binding activity and calcium ion binding activity. Involved in synaptic vesicle priming. Located in endoplasmic reticulum and presynaptic active zone membrane. Is active in cochlear hair cell ribbon synapse and synaptic ve...
Does Knockout of Ythdf1 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,290
Knockout
Ythdf1
cell proliferation
Mouse kidney carcinoma cell
Gene: Ythdf1 (YTH N6-methyladenosine RNA binding protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: immune system process, learning, mRNA destabilization, memory, organelle assembly, positive regulation of translation, positive regulation of translational initiati...
Does Knockout of Fpr2 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
688
Knockout
Fpr2
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Fpr2 (formyl peptide receptor 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway, astrocyte activation, calcium-mediated signaling, cell surface r...
Does Knockout of Zzef1 in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Zzef1
protein/peptide distribution
myoblast cell line
Gene: Zzef1 (zinc finger, ZZ-type with EF hand domain 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: neuroblast proliferation, protein ubiquitination, regulation of synaptic plasticity, synaptic transmission, glutamatergic, visual learning; MF: calcium ion binding, hi...
Does Knockout of Kcnh5 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,280
Knockout
Kcnh5
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Kcnh5 (potassium voltage-gated channel, subfamily H (eag-related), member 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: monoatomic ion transmembrane transport, monoatomic ion transport, potassium ion transmembrane transport, potassium ion transport, regulation ...
Does Knockout of Paip2b in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,265
Knockout
Paip2b
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Paip2b (poly(A) binding protein interacting protein 2B) Type: protein-coding Summary: Predicted to enable mRNA regulatory element binding translation repressor activity and poly(A) binding activity. Predicted to be involved in negative regulation of translational initiation. Predicted to be active...
Does Knockout of Lonrf2 in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Lonrf2
cell viability
Immortal mouse chromaffin cells
Gene: Lonrf2 (LON peptidase N-terminal domain and ring finger 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: motor behavior, negative regulation of neuron apoptotic process, neuromuscular process, neuron apoptotic process, neuron projection development, protein qualit...
Does Knockout of Atxn1l in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
2,173
Knockout
Atxn1l
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Atxn1l (ataxin 1-like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: brain development, extracellular matrix organization, learning, lung alveolus development, memory, negative regulation of transcription by RNA polymerase II, positive regulation of hematopoietic ...
Does Knockout of Gatb in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Gatb
cell proliferation
Colonic Cancer Cell Line
Gene: Gatb (glutamyl-tRNA amidotransferase subunit B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: glutaminyl-tRNAGln biosynthesis via transamidation, mitochondrial translation, translation; MF: ATP binding, carbon-nitrogen ligase activity, with glutamine as amido-N-do...
Does Knockout of Acd in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Acd
cell proliferation
Melanoma Cell Line
Gene: Acd (adrenocortical dysplasia) Type: protein-coding Summary: No summary available. Gene Ontology: BP: embryonic limb morphogenesis, establishment of protein localization to telomere, intracellular protein transport, negative regulation of telomere maintenance via telomerase, positive regu...
Does Knockout of Gemin6 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Gemin6
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Gemin6 (gem nuclear organelle associated protein 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, mRNA processing, spliceosomal complex assembly, spliceosomal snRNP assembly; MF: RNA binding, protein binding; CC: Gemini of Cajal bodies, SMN complex, ...
Does Knockout of Tmem225 in Embryonic Stem Cell Line causally result in cell proliferation?
0
578
Knockout
Tmem225
cell proliferation
Embryonic Stem Cell Line
Gene: Tmem225 (transmembrane protein 225) Type: protein-coding Summary: Enables protein phosphatase 1 binding activity and protein phosphatase inhibitor activity. Involved in negative regulation of phosphatase activity. Located in inner acrosomal membrane and outer acrosomal membrane. Orthologous to hum...
Does Knockout of Rnf2 in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Rnf2
cell viability
Immortal mouse chromaffin cells
Gene: Rnf2 (ring finger protein 2) Type: protein-coding Summary: Enables chromatin binding activity and histone H2AK119 ubiquitin ligase activity. Involved in germ cell development and negative regulation of transcription by RNA polymerase II. Acts upstream of or within with a positive effect on chromat...
Does Knockout of Cd8a in Melanoma Cell Line causally result in cell proliferation?
0
1,270
Knockout
Cd8a
cell proliferation
Melanoma Cell Line
Gene: Cd8a (CD8 subunit alpha) Type: protein-coding Summary: No summary available. Gene Ontology: BP: T cell activation, T cell mediated immunity, T cell receptor signaling pathway, adaptive immune response, cell surface receptor signaling pathway, cytotoxic T cell differentiation, defense resp...
Does Knockout of Lrrn2 in myoblast cell line causally result in protein/peptide distribution?
0
1,679
Knockout
Lrrn2
protein/peptide distribution
myoblast cell line
Gene: Lrrn2 (leucine rich repeat protein 2, neuronal) Type: protein-coding Summary: Predicted to be active in extracellular matrix and extracellular space. Is expressed in several structures, including adrenal medulla; gut; nervous system; optic cup; and urinary system. Orthologous to human LRRN2 (leuci...
Does Knockout of Cinp in Lymphoma Cell Line causally result in response to chemicals?
1
1,530
Knockout
Cinp
response to chemicals
Lymphoma Cell Line
Gene: Cinp (cyclin dependent kinase 2 interacting protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, DNA replication, biological_process, cell division, ribosomal large subunit biogenesis, ribosome biogenesis; MF: molecular_function,...
Does Knockout of Mcts1 in Acute Myeloid Leukemia Cell Line causally result in cell proliferation?
1
684
Knockout
Mcts1
cell proliferation
Acute Myeloid Leukemia Cell Line
Gene: Mcts1 (malignant T cell amplified sequence 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, IRES-dependent viral translational initiation, formation of translation preinitiation complex, ribosome disassembly, translation, translation reinitiat...
Does Knockout of Elovl2 in myoblast cell line causally result in protein/peptide distribution?
0
1,684
Knockout
Elovl2
protein/peptide distribution
myoblast cell line
Gene: Elovl2 (ELOVL fatty acid elongase 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: alpha-linolenic acid metabolic process, fatty acid biosynthetic process, fatty acid derivative biosynthetic process, fatty acid elongation, monounsaturated fatty acid, fatty acid el...
Does Knockout of Mrpl52 in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Mrpl52
cell proliferation
Colonic Cancer Cell Line
Gene: Mrpl52 (mitochondrial ribosomal protein L52) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial translation, translation; MF: structural constituent of ribosome; CC: mitochondrial inner membrane, mitochondrial large ribosomal subunit, mitochondrion, nucle...
Does Knockout of Ddost in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,265
Knockout
Ddost
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Ddost (dolichyl-di-phosphooligosaccharide-protein glycotransferase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: T cell activation, protein N-linked glycosylation, protein N-linked glycosylation via asparagine, protein glycosylation, regulation of protein stabili...
Does Knockout of Mypn in Embryonic Stem Cell Line causally result in cell proliferation?
0
2,477
Knockout
Mypn
cell proliferation
Embryonic Stem Cell Line
Gene: Mypn (myopalladin) Type: protein-coding Summary: No summary available. Gene Ontology: BP: axon guidance, dendrite self-avoidance, homophilic cell adhesion via plasma membrane adhesion molecules, sarcomere organization; MF: SH3 domain binding, actin binding, cell-cell adhesion mediator act...
Does Knockout of Naa38 in Embryonic Stem Cell Line causally result in cell proliferation?
1
579
Knockout
Naa38
cell proliferation
Embryonic Stem Cell Line
Gene: Naa38 (N(alpha)-acetyltransferase 38, NatC auxiliary subunit) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of apoptotic process; MF: RNA binding, molecular_function; CC: NatC complex, cytoplasm, nucleoplasm, nucleus Pathways: ...
Does Knockout of Psma5 in Colonic Cancer Cell Line causally result in cell proliferation?
0
2,176
Knockout
Psma5
cell proliferation
Colonic Cancer Cell Line
Gene: Psma5 (proteasome subunit alpha 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: proteasome-mediated ubiquitin-dependent protein catabolic process, proteolysis involved in protein catabolic process, ubiquitin-dependent protein catabolic process; CC: cytoplasm, cyt...
Does Knockout of P3h1 in Embryonic Stem Cell Line causally result in cell proliferation?
0
579
Knockout
P3h1
cell proliferation
Embryonic Stem Cell Line
Gene: P3h1 (prolyl 3-hydroxylase 1) Type: protein-coding Summary: Predicted to enable procollagen-proline 3-dioxygenase activity. Acts upstream of or within collagen fibril organization; negative regulation of cell growth; and regulation of ossification. Predicted to be located in basement membrane; cyt...
Does Knockout of Enpp3 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Enpp3
cell proliferation
Mouse kidney carcinoma cell
Gene: Enpp3 (ectonucleotide pyrophosphatase/phosphodiesterase 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ATP metabolic process, basophil activation involved in immune response, negative regulation of cGAS/STING signaling pathway, negative regulation of inflammator...
Does Knockout of Nrip2 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,280
Knockout
Nrip2
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Nrip2 (nuclear receptor interacting protein 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Notch signaling pathway, negative regulation of transcription by RNA polymerase II; CC: cytoplasm, nucleus Pathways: UniProt: Q9JHR9 Entrez ID: ...
Does Knockout of Fam98b in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,289
Knockout
Fam98b
cell proliferation
Mouse kidney carcinoma cell
Gene: Fam98b (family with sequence similarity 98, member B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of cell population proliferation, positive regulation of gene expression, protein methylation; MF: identical protein binding, protein methyltran...
Does Knockout of Gas6 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Gas6
protein/peptide distribution
myoblast cell line
Gene: Gas6 (growth arrest specific 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: B cell chemotaxis, activation of protein kinase B activity, animal organ regeneration, apoptotic cell clearance, blood coagulation, calcium ion transmembrane transport, cell differentiat...
Does Knockout of Gpn2 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Gpn2
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Gpn2 (GPN-loop GTPase 2) Type: protein-coding Summary: No summary available. Gene Ontology: MF: GTP binding, GTPase activity, hydrolase activity, nucleotide binding Pathways: UniProt: Q8VEJ1 Entrez ID: 100210
Does Knockout of Cxcl10 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,171
Knockout
Cxcl10
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Cxcl10 (C-X-C motif chemokine ligand 10) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, T cell chemotaxis, adenylate cyclase-activating G protein-coupled receptor signaling pathway, antimicrobial humoral immune response...
Does Knockout of Trpc6 in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Trpc6
cell viability
Immortal mouse chromaffin cells
Gene: Trpc6 (transient receptor potential cation channel, subfamily C, member 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: calcium ion transmembrane transport, calcium ion transport, cellular response to hydrogen peroxide, cellular response to hypoxia, monoatomic io...
Does Knockout of Scn2b in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,440
Knockout
Scn2b
protein/peptide accumulation
Embryonic Cell Line
Gene: Scn2b (sodium channel, voltage-gated, type II, beta) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cardiac conduction, cardiac muscle cell action potential involved in contraction, cardiac muscle contraction, gene expression, membrane depolarization during action ...
Does Knockout of Zfp61 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Zfp61
protein/peptide distribution
myoblast cell line
Gene: Zfp61 (zinc finger protein 61) Type: protein-coding Summary: No summary available. Gene Ontology: MF: DNA binding, metal ion binding, zinc ion binding Pathways: Gene expression (Transcription), Generic Transcription Pathway, Herpes simplex virus 1 infection - Mus musculus (mouse)...
Does Knockout of Gxylt1 in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,044
Knockout
Gxylt1
autophagy
Embryonic Fibroblast Cell Line
Gene: Gxylt1 (glucoside xylosyltransferase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: protein O-linked glycosylation via N-acetyl-galactosamine, protein O-linked glycosylation via glucose; MF: UDP-D-xylose:beta-D-glucoside alpha-1,3-D-xylosyltransferase activity, ...
Does Knockout of Qrich1 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,289
Knockout
Qrich1
cell proliferation
Mouse kidney carcinoma cell
Gene: Qrich1 (glutamine-rich 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: PERK-mediated unfolded protein response, endoplasmic reticulum unfolded protein response, integrated stress response signaling, intrinsic apoptotic signaling pathway in response to endoplasmic...
Does Knockout of Catsperd in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,275
Knockout
Catsperd
cell proliferation
Colonic Cancer Cell Line
Gene: Catsperd (cation channel sperm associated auxiliary subunit delta) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, flagellated sperm motility, sperm capacitation, spermatogenesis; CC: CatSper complex, cell projection, cilium, membrane, motile c...
Does Knockout of N4bp1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,287
Knockout
N4bp1
cell proliferation
Mouse kidney carcinoma cell
Gene: N4bp1 (NEDD4 binding protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to UV, immune system process, innate immune response, negative regulation of cytokine production, negative regulation of proteasomal ubiquitin-dependent protein catabol...
Does Knockout of Psmb7 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Psmb7
cell proliferation
Embryonic Stem Cell Line
Gene: Psmb7 (proteasome (prosome, macropain) subunit, beta type 7) Type: protein-coding Summary: No summary available. Gene Ontology: BP: proteasome-mediated ubiquitin-dependent protein catabolic process, proteolysis, proteolysis involved in protein catabolic process; MF: endopeptidase activity...
Does Knockout of Uba2 in myoblast cell line causally result in protein/peptide distribution?
0
1,682
Knockout
Uba2
protein/peptide distribution
myoblast cell line
Gene: Uba2 (ubiquitin-like modifier activating enzyme 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of protein sumoylation, protein sumoylation; MF: ATP binding, SUMO activating enzyme activity, SUMO binding, magnesium ion binding, metal ion bindi...
Does Knockout of Polr2l in Embryonic Stem Cell Line causally result in cell proliferation?
1
579
Knockout
Polr2l
cell proliferation
Embryonic Stem Cell Line
Gene: Polr2l (polymerase (RNA) II (DNA directed) polypeptide L) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA-templated transcription, tRNA transcription by RNA polymerase III, transcription by RNA polymerase I, transcription by RNA polymerase II; MF: DNA binding, D...
Does Knockout of Nip7 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Nip7
cell proliferation
Embryonic Stem Cell Line
Gene: Nip7 (NIP7, nucleolar pre-rRNA processing protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ribosomal large subunit biogenesis, ribosome assembly, ribosome biogenesis; CC: cytoplasm, cytosol, nucleolus, nucleoplasm, nucleus, preribosome, large subunit precurs...
Does Knockout of Vmn1r46 in myoblast cell line causally result in protein/peptide distribution?
0
1,682
Knockout
Vmn1r46
protein/peptide distribution
myoblast cell line
Gene: Vmn1r46 (vomeronasal 1 receptor 46) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, response to pheromone, sensory perception of chemical stimulus, signal transduction; MF: G protein-coupled receptor activity, pheromone ...