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Does Knockout of Ifna5 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Ifna5
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Ifna5 (interferon alpha 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: B cell activation involved in immune response, T cell activation involved in immune response, adaptive immune response, defense response, defense response to virus, humoral immune response, n...
Does Knockout of Tab2 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in cell proliferation?
1
2,142
Knockout
Tab2
cell proliferation
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Tab2 (TGF-beta activated kinase 1/MAP3K7 binding protein 2) Type: protein-coding Summary: Predicted to enable K63-linked polyubiquitin modification-dependent protein binding activity; molecular adaptor activity; and zinc ion binding activity. Predicted to be involved in several processes, includin...
Does Knockout of Cfap58 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,290
Knockout
Cfap58
cell proliferation
Mouse kidney carcinoma cell
Gene: Cfap58 (cilia and flagella associated protein 58) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Notch signaling pathway, cell projection organization, cilium assembly, flagellated sperm motility, protein localization to motile cilium, sperm axoneme assembly, sperm...
Does Knockout of Atp6v1c1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Atp6v1c1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Atp6v1c1 (ATPase, H+ transporting, lysosomal V1 subunit C1) Type: protein-coding Summary: Enables proton-transporting ATPase activity, rotational mechanism. Involved in synaptic vesicle lumen acidification. Located in plasma membrane. Part of proton-transporting V-type ATPase, V1 domain. Is expres...
Does Knockout of Zfp286 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,271
Knockout
Zfp286
cell proliferation
Mouse kidney carcinoma cell
Gene: Zfp286 (zinc finger protein 286) Type: protein-coding Summary: No summary available. Gene Ontology: BP: regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II; MF: DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, RNA ...
Does Knockout of Vps33b in Colonic Cancer Cell Line causally result in tumorigenicity?
0
2,181
Knockout
Vps33b
tumorigenicity
Colonic Cancer Cell Line
Gene: Vps33b (vacuolar protein sorting 33B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: collagen fibril organization, collagen metabolic process, endosome organization, intracellular protein transport, lysosome localization, megakaryocyte development, melanosome local...
Does Knockout of Sec11c in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Sec11c
protein/peptide distribution
myoblast cell line
Gene: Sec11c (SEC11 homolog C, signal peptidase complex subunit) Type: protein-coding Summary: Predicted to enable serine-type endopeptidase activity. Predicted to be involved in signal peptide processing. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of signal peptidas...
Does Knockout of Zfp335 in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
Zfp335
protein/peptide accumulation
Regulatory T cell
Gene: Zfp335 (zinc finger protein 335) Type: protein-coding Summary: No summary available. Gene Ontology: BP: brain development, brain morphogenesis, cerebral cortex neuron differentiation, epigenetic regulation of gene expression, in utero embryonic development, neuron projection morphogenesis...
Does Knockout of Asxl2 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Asxl2
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Asxl2 (ASXL transcriptional regulator 2) Type: protein-coding Summary: This gene encodes a homolog of the Drosophila Asx gene, which interacts with genes involved in axial patterning. Mice with mutations in this gene display abnormal patterning of the axial skeleton, suggesting a similar function ...
Does Knockout of Taf10 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Taf10
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Taf10 (TATA-box binding protein associated factor 10) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA-templated transcription initiation, G1/S transition of mitotic cell cycle, RNA polymerase II preinitiation complex assembly, SAGA complex assembly, allantois de...
Does Knockout of Nuggc in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,440
Knockout
Nuggc
protein/peptide accumulation
Embryonic Cell Line
Gene: Nuggc (nuclear GTPase, germinal center associated) Type: protein-coding Summary: Predicted to enable GTPase activity. Acts upstream of or within DNA damage response and somatic hypermutation of immunoglobulin genes. Located in nucleus. Orthologous to human NUGGC (nuclear GTPase, germinal center as...
Does Knockout of Foxd1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
165
Knockout
Foxd1
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Foxd1 (forkhead box D1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: anatomical structure morphogenesis, axon guidance, branching involved in ureteric bud morphogenesis, canonical Wnt signaling pathway, cell differentiation, dichotomous subdivision of terminal un...
Does Knockout of Kel in breast epithelium causally result in cell cycle progression?
0
1,470
Knockout
Kel
cell cycle progression
breast epithelium
Gene: Kel (Kell blood group) Type: protein-coding Summary: No summary available. Gene Ontology: BP: establishment of localization in cell, intracellular calcium ion homeostasis, intracellular magnesium ion homeostasis, myelination, negative regulation of potassium ion transmembrane transport, p...
Does Knockout of Gba2 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
2,307
Knockout
Gba2
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Gba2 (glucosidase beta 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: bile acid metabolic process, carbohydrate metabolic process, central nervous system development, central nervous system neuron development, cholesterol metabolic process, glucosylceramide cata...
Does Knockout of Adgrg7 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
687
Knockout
Adgrg7
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Adgrg7 (adhesion G protein-coupled receptor G7) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, cell surface receptor signaling pathway, signal transduction; MF: G protein-coupled receptor activity, transmembrane signali...
Does Knockout of Haus1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,271
Knockout
Haus1
cell proliferation
Mouse kidney carcinoma cell
Gene: Haus1 (HAUS augmin-like complex, subunit 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell division, centrosome cycle, spindle assembly; CC: HAUS complex, centrosome, cytoplasm, cytoskeleton, cytosol, microtubule, mitotic spindle microtubule, spindle, spindle ...
Does Knockout of Cops6 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,265
Knockout
Cops6
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Cops6 (COP9 signalosome subunit 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: protein deneddylation; MF: metallopeptidase activity, peptidase activity, protein binding; CC: COP9 signalosome, cytoplasm, nucleoplasm, nucleus Pathways: Cargo recognition f...
Does Knockout of Mms22l in Embryonic Stem Cell Line causally result in cell proliferation?
1
578
Knockout
Mms22l
cell proliferation
Embryonic Stem Cell Line
Gene: Mms22l (MMS22-like, DNA repair protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, chromatin organization, double-strand break repair via homologous recombination, protein localization to chromatin, replication fork processing; ...
Does Knockout of Qrich1 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Qrich1
cell proliferation
Embryonic Stem Cell Line
Gene: Qrich1 (glutamine-rich 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: PERK-mediated unfolded protein response, endoplasmic reticulum unfolded protein response, integrated stress response signaling, intrinsic apoptotic signaling pathway in response to endoplasmic...
Does Knockout of Cycs in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
1
2,171
Knockout
Cycs
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Cycs (cytochrome c, somatic) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, hydrogen peroxide metabolic process, intrinsic apoptotic signaling pathway, mitochondrial electron transport, cytochrome c to oxygen, mitochondrial electron transport, ub...
Does Knockout of Rraga in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
1,130
Knockout
Rraga
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Rraga (Ras-related GTP binding A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: TORC1 signaling, apoptotic process, autophagosome assembly, cellular response to amino acid starvation, cellular response to amino acid stimulus, cellular response to methionine, cellu...
Does Knockout of Slamf8 in Embryonic Stem Cell Line causally result in cell proliferation?
0
578
Knockout
Slamf8
cell proliferation
Embryonic Stem Cell Line
Gene: Slamf8 (SLAM family member 8) Type: protein-coding Summary: Enables identical protein binding activity and signaling receptor activity. Involved in B-1 B cell lineage commitment and regulation of B cell differentiation. Acts upstream of or within several processes, including leukocyte chemotaxis i...
Does Knockout of Psg26 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Psg26
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Psg26 (pregnancy-specific beta-1-glycoprotein 26) Type: protein-coding Summary: Predicted to be involved in T cell activation and immune response. Predicted to be located in apical plasma membrane and cytosol. Predicted to be active in external side of plasma membrane. Orthologous to human CEACAM2...
Does Knockout of Ube2c in Embryonic Stem Cell Line causally result in cell proliferation?
1
579
Knockout
Ube2c
cell proliferation
Embryonic Stem Cell Line
Gene: Ube2c (ubiquitin-conjugating enzyme E2C) Type: protein-coding Summary: Predicted to enable ubiquitin conjugating enzyme activity and ubiquitin-like protein ligase binding activity. Predicted to contribute to ubiquitin-protein transferase activity. Predicted to be involved in several processes, inc...
Does Knockout of Gm815 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,286
Knockout
Gm815
cell proliferation
Mouse kidney carcinoma cell
Gene: Gm815 (predicted gene 815) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: A0A494BAC9, Q3UWS2 Entrez ID: 329047
Does Knockout of U2af1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
U2af1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: U2af1 (U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, mRNA processing, mRNA splicing, via spliceosome; MF: RNA binding, RS domain binding, metal ion binding, nucleic acid binding, pre-mRNA ...
Does Knockout of Jak2 in Melanoma Cell Line causally result in cell proliferation?
1
1,157
Knockout
Jak2
cell proliferation
Melanoma Cell Line
Gene: Jak2 (Janus kinase 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: T-helper 1 cell differentiation, activation of Janus kinase activity, adaptive immune response, apoptotic signaling pathway, axon regeneration, cell adhesion, cell differentiation, cell surface re...
Does Knockout of 1700020L24Rik in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
1700020L24Rik
cell proliferation
Embryonic Stem Cell Line
Gene: 1700020L24Rik (RIKEN cDNA 1700020L24 gene) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q8C1R3 Entrez ID: 66330
Does Knockout of Nub1 in Colonic Cancer Cell Line causally result in cell proliferation?
0
2,176
Knockout
Nub1
cell proliferation
Colonic Cancer Cell Line
Gene: Nub1 (negative regulator of ubiquitin-like proteins 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of proteasomal ubiquitin-dependent protein catabolic process, proteasomal protein catabolic process, protein ubiquitination, proteolysis involv...
Does Knockout of Crocc in Embryonic Fibroblast Cell Line causally result in response to virus?
1
1,133
Knockout
Crocc
response to virus
Embryonic Fibroblast Cell Line
Gene: Crocc (ciliary rootlet coiled-coil, rootletin) Type: protein-coding Summary: Enables actin binding activity; kinesin binding activity; and structural molecule activity. A structural constituent of cytoskeleton. Acts upstream of or within several processes, including ciliary basal body organization...
Does Knockout of Steap1 in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,044
Knockout
Steap1
autophagy
Embryonic Fibroblast Cell Line
Gene: Steap1 (six transmembrane epithelial antigen of the prostate 1) Type: protein-coding Summary: No summary available. Gene Ontology: MF: heme binding, metal ion binding; CC: endosome, endosome membrane, membrane, plasma membrane Pathways: Mineral absorption - Mus musculus (mouse) ...
Does Knockout of Ankrd52 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,273
Knockout
Ankrd52
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Ankrd52 (ankyrin repeat domain 52) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q8BTI7 Entrez ID: 237615
Does Knockout of Hikeshi in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Hikeshi
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Hikeshi (heat shock protein nuclear import factor) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Golgi organization, cellular response to heat, lung development, protein import into nucleus, protein transport; MF: Hsp70 protein binding, nuclear import signal recep...
Does Knockout of Cldn34b2 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Cldn34b2
protein/peptide distribution
myoblast cell line
Gene: Cldn34b2 (claudin 34B2) Type: protein-coding Summary: Predicted to be involved in bicellular tight junction assembly and cell adhesion. Predicted to be active in bicellular tight junction and plasma membrane. Orthologous to human CLDN34 (claudin 34). [provided by Alliance of Genome Resources, Jul ...
Does Knockout of Tmem88 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Tmem88
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Tmem88 (transmembrane protein 88) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Wnt signaling pathway, negative regulation of canonical Wnt signaling pathway, protein localization to plasma membrane, protein stabilization; MF: PDZ domain binding, protein binding; ...
Does Knockout of Vstm2l in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,262
Knockout
Vstm2l
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Vstm2l (V-set and transmembrane domain containing 2-like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of neuron apoptotic process; CC: cytoplasm, extracellular region, membrane Pathways: UniProt: Q6PDS0 Entrez ID: 2...
Does Knockout of Zfp697 in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Zfp697
cell viability
Immortal mouse chromaffin cells
Gene: Zfp697 (zinc finger protein 697) Type: protein-coding Summary: Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted t...
Does Knockout of Ttc14 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Ttc14
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Ttc14 (tetratricopeptide repeat domain 14) Type: protein-coding Summary: No summary available. Gene Ontology: MF: nucleic acid binding, protein binding Pathways: UniProt: Q9CSP9 Entrez ID: 67120
Does Knockout of Arpc1b in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Arpc1b
protein/peptide distribution
myoblast cell line
Gene: Arpc1b (actin related protein 2/3 complex, subunit 1B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Arp2/3 complex-mediated actin nucleation; MF: actin binding, actin filament binding, protein-containing complex binding, structural constituent of cytoskeleton; CC...
Does Knockout of Trim71 in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Trim71
protein/peptide distribution
Microglial Cell Line
Gene: Trim71 (tripartite motif-containing 71) Type: protein-coding Summary: No summary available. Gene Ontology: BP: 3'-UTR-mediated mRNA destabilization, G1/S transition of mitotic cell cycle, fibroblast growth factor receptor signaling pathway, miRNA processing, miRNA-mediated gene silencing ...
Does Knockout of Elavl1 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,289
Knockout
Elavl1
cell proliferation
Mouse kidney carcinoma cell
Gene: Elavl1 (ELAV like RNA binding protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: 3'-UTR-mediated mRNA stabilization, cell population proliferation, lncRNA-mediated post-transcriptional gene silencing, mRNA destabilization, mRNA stabilization, negative regula...
Does Knockout of Sergef in Melanoma Cell Line causally result in cell proliferation?
0
2,492
Knockout
Sergef
cell proliferation
Melanoma Cell Line
Gene: Sergef (secretion regulating guanine nucleotide exchange factor) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, negative regulation of protein secretion; MF: guanyl-nucleotide exchange factor activity, molecular_function; CC: cellular_component,...
Does Knockout of Otulin in Pancreatic Ductal Adenocarcinoma Cell Line causally result in cell proliferation?
1
2,141
Knockout
Otulin
cell proliferation
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Otulin (OTU deubiquitinase with linear linkage specificity) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Wnt signaling pathway, angiogenesis, immune system process, innate immune response, negative regulation of NF-kappaB transcription factor activity, negative r...
Does Knockout of Tex48 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
687
Knockout
Tex48
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Tex48 (testis expressed 48) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q9DA81 Entrez ID: 75524
Does Knockout of Zfp869 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Zfp869
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Zfp869 (zinc finger protein 869) Type: protein-coding Summary: No summary available. Gene Ontology: BP: regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II; MF: DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, RNA ...
Does Knockout of Rpl35a in myoblast cell line causally result in protein/peptide distribution?
0
1,684
Knockout
Rpl35a
protein/peptide distribution
myoblast cell line
Gene: Rpl35a (ribosomal protein L35A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cytoplasmic translation, rRNA processing, ribosomal large subunit biogenesis, translation, translation at postsynapse, translation at presynapse; MF: ribonucleoprotein complex binding, s...
Does Knockout of Trav19 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
1,130
Knockout
Trav19
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Trav19 (T cell receptor alpha variable 19) Type: other Summary: No summary available. Gene Ontology: BP: adaptive immune response, biological_process, immune system process; MF: molecular_function, peptide antigen binding; CC: T cell receptor complex, cellular_component Pathways:...
Does Knockout of Glra1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Glra1
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Glra1 (glycine receptor, alpha 1 subunit) Type: protein-coding Summary: No summary available. Gene Ontology: BP: acrosome reaction, adult walking behavior, cellular response to amino acid stimulus, cellular response to ethanol, cellular response to zinc ion, chemical synaptic transmission...
Does Knockout of Serpina1d in Colonic Cancer Cell Line causally result in tumorigenicity?
0
2,181
Knockout
Serpina1d
tumorigenicity
Colonic Cancer Cell Line
Gene: Serpina1d (serine (or cysteine) peptidase inhibitor, clade A, member 1D) Type: protein-coding Summary: No summary available. Gene Ontology: BP: response to chromate, response to cytokine, response to lead ion, response to methanol, response to peptide hormone; MF: endopeptidase inhibitor ...
Does Knockout of Zfp932 in myoblast cell line causally result in protein/peptide distribution?
0
1,679
Knockout
Zfp932
protein/peptide distribution
myoblast cell line
Gene: Zfp932 (zinc finger protein 932) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, negative regulation of DNA-binding transcription factor activity, negative regulation of cell differentiation, negative regulation of osteoblast differentiation, n...
Does Knockout of Emx1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
165
Knockout
Emx1
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Emx1 (empty spiracles homeobox 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: brain development, brain morphogenesis, central nervous system development, cerebral cortex development, cerebral cortex neuron differentiation, cerebral cortex regionalization, homeos...
Does Knockout of Tatdn2 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,273
Knockout
Tatdn2
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Tatdn2 (TatD DNase domain containing 2) Type: protein-coding Summary: Is expressed in several structures, including brain; cardiovascular system; genitourinary system; gut; and hemolymphoid system. Orthologous to human TATDN2 (TatD DNase domain containing 2). [provided by Alliance of Genome Resour...
Does Knockout of Mgl2 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,289
Knockout
Mgl2
cell proliferation
Mouse kidney carcinoma cell
Gene: Mgl2 (macrophage galactose N-acetyl-galactosamine specific lectin 2) Type: protein-coding Summary: No summary available. Gene Ontology: MF: D-mannose binding, carbohydrate binding, fucose binding, pattern recognition receptor activity; CC: external side of plasma membrane, membrane ...
Does Knockout of Asb5 in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Asb5
protein/peptide distribution
myoblast cell line
Gene: Asb5 (ankyrin repeat and SOCs box-containing 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: intracellular signal transduction, positive regulation of protein catabolic process, protein ubiquitination Pathways: Adaptive Immune System, Antigen processing:...
Does Knockout of Abca5 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,440
Knockout
Abca5
protein/peptide accumulation
Embryonic Cell Line
Gene: Abca5 (ATP-binding cassette, sub-family A member 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cholesterol efflux, cholesterol homeostasis, cholesterol metabolic process, high-density lipoprotein particle remodeling, lipid transport, negative regulation of macr...
Does Knockout of Ebf3 in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Ebf3
protein/peptide distribution
myoblast cell line
Gene: Ebf3 (early B cell factor 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of DNA-templated transcription, positive regulation of transcription by RNA polymerase II, regulation of DNA-templated transcription, regulation of transcription by RNA ...
Does Knockout of Nkx1-2 in myoblast cell line causally result in protein/peptide distribution?
0
1,681
Knockout
Nkx1-2
protein/peptide distribution
myoblast cell line
Gene: Nkx1-2 (NK1 homeobox 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II; MF: DNA binding, DNA-binding transcription factor activity, RNA polymerase II-s...
Does Knockout of Hdgfl1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,286
Knockout
Hdgfl1
cell proliferation
Mouse kidney carcinoma cell
Gene: Hdgfl1 (HDGF like 1) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q2VPR5 Entrez ID: 15192
Does Knockout of Gpr26 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,280
Knockout
Gpr26
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Gpr26 (G protein-coupled receptor 26) Type: protein-coding Summary: Predicted to enable G protein-coupled receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Is expressed in central ne...
Does Knockout of Mettl14 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
1
2,172
Knockout
Mettl14
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Mettl14 (methyltransferase 14, N6-adenosine-methyltransferase subunit) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA methylation, cell differentiation, forebrain radial glial cell differentiation, gliogenesis, mRNA destabilization, mRNA export from nucleus, mR...
Does Knockout of Eftud2 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Eftud2
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Eftud2 (elongation factor Tu GTP binding domain containing 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, mRNA processing, mRNA splicing, via spliceosome; MF: GTP binding, GTPase activity, U5 snRNA binding, nucleotide binding, protein binding; CC: ...
Does Knockout of Sgf29 in Microglial Cell Line causally result in response to virus?
1
2,429
Knockout
Sgf29
response to virus
Microglial Cell Line
Gene: Sgf29 (SAGA complex associated factor 29) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chromatin organization, negative regulation of DNA repair, negative regulation of transcription by RNA polymerase II, positive regulation of DNA-templated transcription, regula...
Does Knockout of Dcaf6 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Dcaf6
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Dcaf6 (DDB1 and CUL4 associated factor 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of transcription by RNA polymerase II, protein ubiquitination; MF: transcription coactivator activity; CC: Cul4-RING E3 ubiquitin ligase complex, cytoplasm,...
Does Knockout of Ndc80 in Acute Myeloid Leukemia Cell Line causally result in cell proliferation?
1
684
Knockout
Ndc80
cell proliferation
Acute Myeloid Leukemia Cell Line
Gene: Ndc80 (NDC80 kinetochore complex component) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G2/MI transition of meiotic cell cycle, attachment of mitotic spindle microtubules to kinetochore, attachment of spindle microtubules to kinetochore, cell division, centrosom...
Does Knockout of Ctr9 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,262
Knockout
Ctr9
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Ctr9 (CTR9 homolog, Paf1/RNA polymerase II complex component) Type: protein-coding Summary: Enables SH2 domain binding activity. Involved in several processes, including cell surface receptor signaling pathway; cellular response to lipopolysaccharide; and endodermal cell fate commitment. Acts upst...
Does Knockout of Rbm26 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Rbm26
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Rbm26 (RNA binding motif protein 26) Type: protein-coding Summary: Predicted to enable RNA binding activity. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; sensory organ; and submandibular gland. Ortho...
Does Knockout of 4930455H04Rik in macrophage causally result in phagocytosis?
0
1,888
Knockout
4930455H04Rik
phagocytosis
macrophage
Gene: 4930455H04Rik (RIKEN cDNA 4930455H04 gene) Type: ncRNA Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID: 74654
Does Knockout of Trim43a in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,152
Knockout
Trim43a
protein/peptide accumulation
Embryonic Cell Line
Gene: Trim43a (tripartite motif-containing 43A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: innate immune response, regulation of gene expression; MF: metal ion binding, protein kinase binding, ubiquitin protein ligase activity, zinc ion binding Pathways: ...
Does Knockout of St6galnac2 in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
St6galnac2
protein/peptide accumulation
Regulatory T cell
Gene: St6galnac2 (ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: carbohydrate derivative biosynthetic process, protein O-linked glycosylation, protein glycosyla...
Does Knockout of Sphk2 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Sphk2
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Sphk2 (sphingosine kinase 2) Type: protein-coding Summary: This gene encodes a kinase that phosphorylates sphingosine into sphingosine-1-phosphate, which is involved in cell differentiation, motility, and apoptosis. The encoded protein plays a role in maintaining cellular levels of sphingosine-1-p...
Does Knockout of Lin9 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,265
Knockout
Lin9
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Lin9 (lin-9 DREAM MuvB core complex component) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA biosynthetic process, DNA-templated transcription, regulation of cell cycle, regulation of transcription by RNA polymerase II; CC: nucleoplasm, nucleus, transcription ...
Does Knockout of Foxi1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Foxi1
cell proliferation
Mouse kidney carcinoma cell
Gene: Foxi1 (forkhead box I1) Type: protein-coding Summary: Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts ups...
Does Knockout of Klrc1 in Embryonic Stem Cell Line causally result in cell proliferation?
0
2,477
Knockout
Klrc1
cell proliferation
Embryonic Stem Cell Line
Gene: Klrc1 (killer cell lectin-like receptor subfamily C, member 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: adaptive immune response, immune response-regulating cell surface receptor signaling pathway, immune system process, innate immune response, positive regul...
Does Knockout of Vil1 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,280
Knockout
Vil1
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Vil1 (villin 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: actin filament capping, actin filament depolymerization, actin filament polymerization, actin filament severing, actin polymerization or depolymerization, apoptotic process, barbed-end actin filament ca...
Does Knockout of Pbrm1 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Pbrm1
protein/peptide distribution
myoblast cell line
Gene: Pbrm1 (polybromo 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: blastocyst formation, blood vessel remodeling, cardiac vascular smooth muscle cell development, chromatin organization, chromatin remodeling, epicardium-derived cardiac endothelial cell differentiat...
Does Knockout of Mia2 in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Mia2
protein/peptide distribution
myoblast cell line
Gene: Mia2 (MIA SH3 domain ER export factor 2) Type: protein-coding Summary: This gene encodes a protein that is involved in endoplasmic reticulum-to-Golgi trafficking and regulation of cholesterol metabolism. Three major classes of transcripts are generated from this gene- melanoma inhibitory activity ...
Does Knockout of Hbq1b in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Hbq1b
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Hbq1b (hemoglobin, theta 1B) Type: protein-coding Summary: This gene is one of two mouse theta-globin genes found in the alpha-globin gene cluster on chromosome 11. This gene represents the T1 (or 5') theta-globin gene described in PMIDs 18245844 and 11157800, respectively. [provided by RefSeq, Ap...
Does Knockout of Dmap1 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,289
Knockout
Dmap1
cell proliferation
Mouse kidney carcinoma cell
Gene: Dmap1 (DNA methyltransferase 1-associated protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA repair, chromatin organization, chromatin remodeling, negative regulation of DNA-templated transcription, negative regulation of transcription by RNA polymerase ...
Does Knockout of Lrrc56 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
688
Knockout
Lrrc56
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Lrrc56 (leucine rich repeat containing 56) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, cell projection organization; CC: cell projection, cellular_component, cilium Pathways: UniProt: Q8K375 Entrez ID: 70552
Does Knockout of Gm14151 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Gm14151
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Gm14151 (predicted gene 14151) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, cellular response to glucose starvation; MF: ATP binding, kinase activity, molecular_function, nucleotide binding, protein kinase activity, protein serine/threonine ki...
Does Knockout of Atp6v1g1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Atp6v1g1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Atp6v1g1 (ATPase, H+ transporting, lysosomal V1 subunit G1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to increased oxygen levels, intracellular iron ion homeostasis, monoatomic ion transport, proton transmembrane transport, synaptic vesicle l...
Does Knockout of Qtrt2 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,262
Knockout
Qtrt2
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Qtrt2 (queuine tRNA-ribosyltransferase accessory subunit 2) Type: protein-coding Summary: Predicted to enable protein heterodimerization activity; protein homodimerization activity; and tRNA binding activity. Involved in tRNA-guanine transglycosylation. Located in cytoplasmic side of mitochondrial...
Does Knockout of Adprh in myoblast cell line causally result in protein/peptide distribution?
0
1,682
Knockout
Adprh
protein/peptide distribution
myoblast cell line
Gene: Adprh (ADP-ribosylarginine hydrolase) Type: protein-coding Summary: Enables ADP-ribosylarginine hydrolase activity. Involved in protein modification process. Predicted to be located in extracellular space. Is expressed in cerebral cortex. Orthologous to human ADPRH (ADP-ribosylarginine hydrolase)....
Does Knockout of Lcp1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Lcp1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Lcp1 (lymphocyte cytosolic protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: T cell activation involved in immune response, actin cytoskeleton organization, actin filament bundle assembly, actin filament network formation, animal organ regeneration, cell mi...
Does Knockout of Fst in Regulatory T cell causally result in cell proliferation?
0
2,127
Knockout
Fst
cell proliferation
Regulatory T cell
Gene: Fst (follistatin) Type: protein-coding Summary: The protein encoded by this gene binds to and negatively regulates activin, as well as other members of the transforming growth factor beta family, and acts to prevent uncontrolled cellular proliferation. This protein also contains a heparin-binding ...
Does Knockout of Oaz1 in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
Oaz1
response to virus
Embryonic Fibroblast Cell Line
Gene: Oaz1 (ornithine decarboxylase antizyme 1) Type: protein-coding Summary: The protein encoded by this gene belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamine levels. Expression of antizymes requires +1 rib...
Does Knockout of Trappc4 in Embryonic Stem Cell Line causally result in cell proliferation?
1
579
Knockout
Trappc4
cell proliferation
Embryonic Stem Cell Line
Gene: Trappc4 (trafficking protein particle complex 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: COPII vesicle coating, autophagy, dendrite development, endoplasmic reticulum to Golgi vesicle-mediated transport, vesicle coating, vesicle tethering, vesicle-mediated t...
Does Knockout of Txnl4a in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Txnl4a
cell proliferation
Embryonic Stem Cell Line
Gene: Txnl4a (thioredoxin-like 4A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, cell division, mRNA processing, mRNA splicing, via spliceosome; MF: molecular_function, protein-N-terminal amino-acid acetyltransferase activity; CC: Golgi apparatus, NatA com...
Does Knockout of Dpys in myoblast cell line causally result in protein/peptide distribution?
0
1,679
Knockout
Dpys
protein/peptide distribution
myoblast cell line
Gene: Dpys (dihydropyrimidinase) Type: protein-coding Summary: Enables dihydropyrimidinase activity and phosphoprotein binding activity. Involved in pyrimidine nucleoside monophosphate catabolic process. Is active in cytosol. Is expressed in cranium. Human ortholog(s) of this gene implicated in dihydrop...
Does Knockout of Abhd1 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Abhd1
protein/peptide distribution
myoblast cell line
Gene: Abhd1 (abhydrolase domain containing 1) Type: protein-coding Summary: Predicted to enable acetylesterase activity and monoacylglycerol lipase activity. Predicted to be involved in medium-chain fatty acid biosynthetic process and medium-chain fatty acid catabolic process. Predicted to be located in...
Does Knockout of Dhrs13 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Dhrs13
protein/peptide distribution
myoblast cell line
Gene: Dhrs13 (dehydrogenase/reductase 13) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q5SS80 Entrez ID: 70451
Does Knockout of Atp4b in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Atp4b
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Atp4b (ATPase, H+/K+ exchanging, beta polypeptide) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell adhesion, intracellular potassium ion homeostasis, intracellular sodium ion homeostasis, monoatomic ion transport, pH reduction, potassium ion import across plasm...
Does Knockout of Apaf1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
81
Knockout
Apaf1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Apaf1 (apoptotic peptidase activating factor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, apoptotic signaling pathway, brain development, cardiac muscle cell apoptotic process, cell differentiation, cellular response to transforming growth f...
Does Knockout of Krtap26-1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,286
Knockout
Krtap26-1
cell proliferation
Mouse kidney carcinoma cell
Gene: Krtap26-1 (keratin associated protein 26-1) Type: protein-coding Summary: No summary available. Gene Ontology: MF: molecular_function, structural molecule activity; CC: cellular_component, cytosol, intermediate filament, keratin filament Pathways: UniProt: Q9D7N2 ...
Does Knockout of Ncl in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Ncl
cell proliferation
Colonic Cancer Cell Line
Gene: Ncl (nucleolin) Type: protein-coding Summary: No summary available. Gene Ontology: BP: angiogenesis, cellular response to epidermal growth factor stimulus, cellular response to leukemia inhibitory factor, cellular response to lipopolysaccharide, endocytosis, negative regulation of apoptot...
Does Knockout of Sgce in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
2,307
Knockout
Sgce
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Sgce (sarcoglycan, epsilon) Type: protein-coding Summary: No summary available. Gene Ontology: CC: Golgi apparatus, cell projection, cytoplasm, cytoskeleton, dendrite, dendrite membrane, dystrophin-associated glycoprotein complex, membrane, plasma membrane, sarcoglycan complex, sarcolemma...
Does Knockout of Fthl17a in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Fthl17a
cell proliferation
Embryonic Stem Cell Line
Gene: Fthl17a (ferritin, heavy polypeptide-like 17, member A) Type: protein-coding Summary: Predicted to enable ferric iron binding activity and ferrous iron binding activity. Predicted to be active in cytoplasm. Orthologous to several human genes including FTHL17 (ferritin heavy chain like 17). [provid...
Does Knockout of Prpf8 in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Prpf8
cell proliferation
Melanoma Cell Line
Gene: Prpf8 (pre-mRNA processing factor 8) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, cellular response to lipopolysaccharide, cellular response to tumor necrosis factor, mRNA processing, mRNA splicing, via spliceosome, spliceosomal tri-snRNP complex as...
Does Knockout of Dock8 in myoblast cell line causally result in protein/peptide distribution?
0
1,684
Knockout
Dock8
protein/peptide distribution
myoblast cell line
Gene: Dock8 (dedicator of cytokinesis 8) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to chemokine, dendritic cell migration, immunological synapse formation, memory T cell proliferation, negative regulation of T cell apoptotic process, positive regul...
Does Knockout of Brap in Embryonic Stem Cell Line causally result in cell proliferation?
1
579
Knockout
Brap
cell proliferation
Embryonic Stem Cell Line
Gene: Brap (BRCA1 associated protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: MAPK cascade, Ras protein signal transduction, negative regulation of signal transduction, protein ubiquitination; MF: identical protein binding, metal ion binding, nuclear localization ...