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Does Knockout of Zdhhc14 in Embryonic Stem Cell Line causally result in cell proliferation?
0
579
Knockout
Zdhhc14
cell proliferation
Embryonic Stem Cell Line
Gene: Zdhhc14 (zinc finger, DHHC domain containing 14) Type: protein-coding Summary: No summary available. Gene Ontology: BP: peptidyl-L-cysteine S-palmitoylation, protein targeting to membrane; MF: acyltransferase activity, palmitoyltransferase activity, protein-cysteine S-palmitoyltransferase...
Does Knockout of Rhog in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Rhog
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Rhog (ras homolog family member G) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Rac protein signal transduction, Rho protein signal transduction, actin cytoskeleton organization, actin filament organization, activation of GTPase activity, cell chemotaxis, cortica...
Does Knockout of Upp2 in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Upp2
protein/peptide distribution
myoblast cell line
Gene: Upp2 (uridine phosphorylase 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: CMP catabolic process, UMP catabolic process, UMP salvage, dCMP catabolic process, nucleoside metabolic process, nucleotide catabolic process, uridine catabolic process; MF: catalytic act...
Does Knockout of Letm2 in macrophage causally result in phagocytosis?
0
1,888
Knockout
Letm2
phagocytosis
macrophage
Gene: Letm2 (leucine zipper-EF-hand containing transmembrane protein 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial calcium ion transmembrane transport, mitochondrion organization; MF: molecular_function, ribosome binding, transmembrane transporter activ...
Does Knockout of Kif1a in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Kif1a
response to chemicals
Pancreatic Cancer Cell Line
Gene: Kif1a (kinesin family member 1A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: anterograde axonal transport, anterograde dendritic transport, anterograde neuronal dense core vesicle transport, anterograde synaptic vesicle transport, dense core granule cytoskeletal...
Does Knockout of Hsf2 in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Hsf2
protein/peptide distribution
myoblast cell line
Gene: Hsf2 (heat shock factor 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of transcription by RNA polymerase II, regulation of DNA-templated transcription, spermatogenesis; MF: DNA binding, DNA-binding transcription activator activity, RNA polym...
Does Knockout of Dimt1 in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
Dimt1
protein/peptide accumulation
Regulatory T cell
Gene: Dimt1 (DIM1 rRNA methyltransferase and ribosome maturation factor) Type: protein-coding Summary: No summary available. Gene Ontology: BP: methylation, positive regulation of rRNA processing, rRNA methylation, rRNA modification, rRNA processing, ribosomal small subunit biogenesis; MF: 18S ...
Does Knockout of Rpp25 in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Rpp25
cell viability
Immortal mouse chromaffin cells
Gene: Rpp25 (ribonuclease P/MRP 25 subunit) Type: protein-coding Summary: No summary available. Gene Ontology: BP: rRNA processing, tRNA 5'-leader removal, tRNA processing; MF: RNA binding, nucleic acid binding, ribonuclease P RNA binding, ribonuclease P activity; CC: centriolar satellite, mult...
Does Knockout of Foxc1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Foxc1
cell proliferation
Mouse kidney carcinoma cell
Gene: Foxc1 (forkhead box C1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Notch signaling pathway, anatomical structure morphogenesis, angiogenesis, artery morphogenesis, blood vessel development, blood vessel diameter maintenance, blood vessel remodeling, brain devel...
Does Knockout of Ostm1 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Ostm1
cell proliferation
Embryonic Stem Cell Line
Gene: Ostm1 (osteopetrosis associated transmembrane protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: osteoclast differentiation, transepithelial chloride transport; CC: chloride channel complex, cytosol, lysosomal membrane, lysosome, membrane Pathways: ...
Does Knockout of Ccdc93 in Melanoma Cell Line causally result in cell proliferation?
0
2,492
Knockout
Ccdc93
cell proliferation
Melanoma Cell Line
Gene: Ccdc93 (coiled-coil domain containing 93) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Golgi to plasma membrane transport, endocytic recycling, protein transport; CC: early endosome, endosome Pathways: UniProt: Q7TQK5 Entrez ID: 70829
Does Knockout of Gemin2 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
1
2,307
Knockout
Gemin2
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Gemin2 (gem nuclear organelle associated protein 2) Type: protein-coding Summary: This gene encodes one of the proteins found in the survival of motor neuron (SMN) complex, which consists of the SMN protein and several gemin proteins. The SMN complex is localized to a subnuclear compartment called...
Does Knockout of Cyb5r2 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Cyb5r2
protein/peptide distribution
myoblast cell line
Gene: Cyb5r2 (cytochrome b5 reductase 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: lipid metabolic process, steroid biosynthetic process, steroid metabolic process, sterol biosynthetic process; MF: FAD binding, cytochrome-b5 reductase activity, acting on NAD(P)H, ox...
Does Knockout of Ctcf in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Ctcf
cell proliferation
Colonic Cancer Cell Line
Gene: Ctcf (CCCTC-binding factor) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA methylation-dependent constitutive heterochromatin formation, cardiac muscle cell development, cardiac muscle cell differentiation, chromatin looping, chromatin organization, chromosome ...
Does Knockout of Lpcat2b in macrophage causally result in phagocytosis?
0
1,888
Knockout
Lpcat2b
phagocytosis
macrophage
Gene: Lpcat2b (lysophosphatidylcholine acyltransferase 2B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, glycerolipid metabolic process, lipid metabolic process, phospholipid biosynthetic process, phospholipid metabolic process; MF: 1-acylglycerophos...
Does Knockout of Vmn1r80 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Vmn1r80
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Vmn1r80 (vomeronasal 1 receptor 80) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, response to pheromone, sensory perception of chemical stimulus, signal transduction; MF: G protein-coupled receptor activity, pheromone ...
Does Knockout of Cnfn in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,286
Knockout
Cnfn
cell proliferation
Mouse kidney carcinoma cell
Gene: Cnfn (cornifelin) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, keratinization; CC: cornified envelope, cytoplasm Pathways: UniProt: Q6PCW6 Entrez ID: 72383
Does Knockout of Ppp1r1a in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
1,130
Knockout
Ppp1r1a
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Ppp1r1a (protein phosphatase 1, regulatory inhibitor subunit 1A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: glycogen metabolic process, intracellular signal transduction, signal transduction; MF: protein binding, protein phosphatase inhibitor activity; CC: cyto...
Does Knockout of Itga5 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,152
Knockout
Itga5
protein/peptide accumulation
Embryonic Cell Line
Gene: Itga5 (integrin alpha 5 (fibronectin receptor alpha)) Type: protein-coding Summary: The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain,...
Does Knockout of D630023F18Rik in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,265
Knockout
D630023F18Rik
cell proliferation
Mammary Gland Tumor Cell Line
Gene: D630023F18Rik (RIKEN cDNA D630023F18 gene) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q8C3M9 Entrez ID: 98303
Does Knockout of Zdhhc11 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,273
Knockout
Zdhhc11
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Zdhhc11 (zinc finger, DHHC domain containing 11) Type: protein-coding Summary: No summary available. Gene Ontology: BP: antiviral innate immune response, peptidyl-L-cysteine S-palmitoylation, positive regulation of defense response to virus by host, protein targeting to membrane; MF: acyl...
Does Knockout of Inpp5j in Melanoma Cell Line causally result in cell proliferation?
0
1,270
Knockout
Inpp5j
cell proliferation
Melanoma Cell Line
Gene: Inpp5j (inositol polyphosphate 5-phosphatase J) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of microtubule polymerization, negative regulation of neuron projection development, phosphatidylinositol dephosphorylation; MF: SH3 domain binding, h...
Does Knockout of Enpp1 in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Enpp1
protein/peptide distribution
myoblast cell line
Gene: Enpp1 (ectonucleotide pyrophosphatase/phosphodiesterase 1) Type: protein-coding Summary: This gene encodes a member of the nucleoside pyrophosphatase/phosphodiesterase family of enzymes that catalyzes the hydrolysis of pyrophosphate and phosphodiester bonds in nucleotide triphosphates and oligonuc...
Does Knockout of Alox12 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,280
Knockout
Alox12
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Alox12 (arachidonate 12-lipoxygenase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: arachidonate metabolic process, cellular response to lipid, establishment of skin barrier, fatty acid metabolic process, fatty acid oxidation, hepoxilin biosynthetic process, leuko...
Does Knockout of Defb34 in myoblast cell line causally result in protein/peptide distribution?
0
1,681
Knockout
Defb34
protein/peptide distribution
myoblast cell line
Gene: Defb34 (defensin beta 34) Type: protein-coding Summary: No summary available. Gene Ontology: BP: defense response, defense response to bacterium, innate immune response; MF: CCR2 chemokine receptor binding, heparin binding, lipopolysaccharide binding; CC: extracellular region, membrane, m...
Does Knockout of Spc24 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,289
Knockout
Spc24
cell proliferation
Mouse kidney carcinoma cell
Gene: Spc24 (SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: attachment of spindle microtubules to kinetochore, cell division, chromosome segregation, mitotic spindle assembly checkpoint signaling; CC: N...
Does Knockout of Cenpm in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Cenpm
cell proliferation
Colonic Cancer Cell Line
Gene: Cenpm (centromere protein M) Type: protein-coding Summary: This gene encodes a protein that is present in the nucleus of actively growing cells but is excluded from the nucleus during cell division or during growth arrest as a result of contact inhibition. In human, this protein is a component of ...
Does Knockout of Safb in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,289
Knockout
Safb
cell proliferation
Mouse kidney carcinoma cell
Gene: Safb (scaffold attachment factor B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: estrogen receptor signaling pathway, hormone metabolic process, positive regulation of transcription by RNA polymerase II, regulation of androgen receptor signaling pathway, regulati...
Does Knockout of Dcp2 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Dcp2
cell proliferation
Embryonic Stem Cell Line
Gene: Dcp2 (decapping mRNA 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: deadenylation-dependent decapping of nuclear-transcribed mRNA, histone mRNA catabolic process, mRNA catabolic process, negative regulation of telomere maintenance via telomerase, nuclear-transcr...
Does Knockout of Ranbp1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
82
Knockout
Ranbp1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Ranbp1 (RAN binding protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: nucleocytoplasmic transport, positive regulation of mitotic centrosome separation, spindle organization; MF: GTPase activator activity; CC: axon cytoplasm, centrosome, cytoplasm, cytosol,...
Does Knockout of Mir6960 in breast epithelium causally result in cell cycle progression?
0
1,468
Knockout
Mir6960
cell cycle progression
breast epithelium
Gene: Mir6960 (microRNA 6960) Type: ncRNA Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase...
Does Knockout of Jsrp1 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Jsrp1
protein/peptide distribution
myoblast cell line
Gene: Jsrp1 (junctional sarcoplasmic reticulum protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: protein localization to membrane, skeletal muscle contraction; CC: endoplasmic reticulum, endoplasmic reticulum membrane, membrane, sarcoplasmic reticulum, sarcoplasm...
Does Knockout of Eftud2 in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
Eftud2
response to virus
Embryonic Fibroblast Cell Line
Gene: Eftud2 (elongation factor Tu GTP binding domain containing 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, mRNA processing, mRNA splicing, via spliceosome; MF: GTP binding, GTPase activity, U5 snRNA binding, nucleotide binding, protein binding; CC: ...
Does Knockout of Hhla1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Hhla1
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Hhla1 (HERV-H LTR-associating 1) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cellular_component, extracellular region Pathways: UniProt: Q3TYV2 Entrez ID: 654498
Does Knockout of Vmn1r237 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,271
Knockout
Vmn1r237
cell proliferation
Mouse kidney carcinoma cell
Gene: Vmn1r237 (vomeronasal 1 receptor 237) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, response to pheromone, sensory perception of chemical stimulus, signal transduction; MF: G protein-coupled receptor activity, pheromon...
Does Knockout of Shc1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,289
Knockout
Shc1
cell proliferation
Mouse kidney carcinoma cell
Gene: Shc1 (src homology 2 domain-containing transforming protein C1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: B cell receptor signaling pathway, actin cytoskeleton organization, angiogenesis, cell-cell adhesion, cellular response to growth factor stimulus, defense...
Does Knockout of Tmprss11c in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,262
Knockout
Tmprss11c
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Tmprss11c (transmembrane protease, serine 11c) Type: protein-coding Summary: No summary available. Gene Ontology: BP: proteolysis, self proteolysis; MF: hydrolase activity, peptidase activity, serine-type endopeptidase activity, serine-type peptidase activity; CC: cell projection, dendrit...
Does Knockout of Foxi1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Foxi1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Foxi1 (forkhead box I1) Type: protein-coding Summary: Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts ups...
Does Knockout of Dhrs9 in Embryonic Stem Cell Line causally result in cell proliferation?
0
2,477
Knockout
Dhrs9
cell proliferation
Embryonic Stem Cell Line
Gene: Dhrs9 (dehydrogenase/reductase 9) Type: protein-coding Summary: No summary available. Gene Ontology: BP: 9-cis-retinoic acid biosynthetic process, androgen metabolic process, lipid metabolic process, progesterone metabolic process, retinoic acid biosynthetic process, steroid metabolic pro...
Does Knockout of Egr2 in myoblast cell line causally result in protein/peptide distribution?
0
1,681
Knockout
Egr2
protein/peptide distribution
myoblast cell line
Gene: Egr2 (early growth response 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Schwann cell differentiation, aorta development, brain segmentation, facial nerve structural organization, fat cell differentiation, gene expression, motor neuron axon guidance, myelinati...
Does Knockout of Phf20l1 in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Phf20l1
cell viability
Immortal mouse chromaffin cells
Gene: Phf20l1 (PHD finger protein 20-like 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of proteasomal ubiquitin-dependent protein catabolic process, negative regulation of protein catabolic process, regulation of transcription by RNA polymerase I...
Does Knockout of Ifi209 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Ifi209
protein/peptide distribution
myoblast cell line
Gene: Ifi209 (interferon activated gene 209) Type: protein-coding Summary: No summary available. Gene Ontology: BP: activation of innate immune response, cellular response to interferon-beta; CC: cytosol, nucleoplasm, nucleus Pathways: UniProt: Q8BV49 Entrez ID: 23631...
Does Knockout of Lrrc30 in Embryonic Stem Cell Line causally result in cell proliferation?
0
2,477
Knockout
Lrrc30
cell proliferation
Embryonic Stem Cell Line
Gene: Lrrc30 (leucine rich repeat containing 30) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q3UV48 Entrez ID: 240131
Does Knockout of Gm10413 in macrophage causally result in phagocytosis?
1
1,888
Knockout
Gm10413
phagocytosis
macrophage
Gene: Gm10413 (predicted gene 10413) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: E9PZN8, Q497R9, L7N2C6 Entrez ID: 100041774
Does Knockout of Vapb in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Vapb
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Vapb (vesicle-associated membrane protein, associated protein B and C) Type: protein-coding Summary: No summary available. Gene Ontology: BP: COPII-coated vesicle budding, IRE1-mediated unfolded protein response, cholesterol transport, endoplasmic reticulum membrane organization, endoplas...
Does Knockout of Sell in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
83
Knockout
Sell
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Sell (selectin, lymphocyte) Type: protein-coding Summary: No summary available. Gene Ontology: BP: calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules, cell adhesion, heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules, heterotypic cell...
Does Knockout of Pmaip1 in myoblast cell line causally result in protein/peptide distribution?
0
1,679
Knockout
Pmaip1
protein/peptide distribution
myoblast cell line
Gene: Pmaip1 (phorbol-12-myristate-13-acetate-induced protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, T cell homeostasis, apoptotic process, cellular response to glucose starvation, defense response to virus, intrinsic apoptotic signaling p...
Does Knockout of 4930550C14Rik in Embryonic Fibroblast Cell Line causally result in response to virus?
1
1,133
Knockout
4930550C14Rik
response to virus
Embryonic Fibroblast Cell Line
Gene: 4930550C14Rik (RIKEN cDNA 4930550C14 gene) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of mitochondrial fission, negative regulation of protein targeting to mitochondrion; CC: cytoplasm, cytosol, membrane, mitochondrial outer membrane, mitoch...
Does Knockout of Fnbp4 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,262
Knockout
Fnbp4
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Fnbp4 (formin binding protein 4) Type: protein-coding Summary: Predicted to be located in nucleoplasm. Is expressed in endolymphatic appendage and otocyst. Orthologous to human FNBP4 (formin binding protein 4). [provided by Alliance of Genome Resources, Jul 2025] Gene Ontology: ...
Does Knockout of Lsr in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,152
Knockout
Lsr
protein/peptide accumulation
Embryonic Cell Line
Gene: Lsr (lipolysis stimulated lipoprotein receptor) Type: protein-coding Summary: No summary available. Gene Ontology: BP: epithelial structure maintenance, establishment of blood-brain barrier, establishment of skin barrier, lipoprotein transport, liver development, protein localization to t...
Does Knockout of Il12rb1 in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Il12rb1
protein/peptide distribution
myoblast cell line
Gene: Il12rb1 (interleukin 12 receptor, beta 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: T-helper 1 cell differentiation, cellular response to type II interferon, cytokine-mediated signaling pathway, interleukin-12-mediated signaling pathway, interleukin-23-mediate...
Does Knockout of Cdk5 in Colonic Cancer Cell Line causally result in tumorigenicity?
0
2,181
Knockout
Cdk5
tumorigenicity
Colonic Cancer Cell Line
Gene: Cdk5 (cyclin dependent kinase 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, Schwann cell development, apoptotic process, associative learning, axonogenesis, behavioral response to cocaine, calcium ion import, cell division, cell migration, ...
Does Knockout of Ajap1 in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Ajap1
protein/peptide distribution
Microglial Cell Line
Gene: Ajap1 (adherens junction associated protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell adhesion, negative regulation of cell-matrix adhesion, negative regulation of wound healing, regulation of polarized epithelial cell differentiation; MF: beta-catenin...
Does Knockout of Zfp459 in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
Zfp459
response to virus
Embryonic Fibroblast Cell Line
Gene: Zfp459 (zinc finger protein 459) Type: protein-coding Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcrip...
Does Knockout of Ptar1 in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,275
Knockout
Ptar1
cell proliferation
Colonic Cancer Cell Line
Gene: Ptar1 (protein prenyltransferase alpha subunit repeat containing 1) Type: protein-coding Summary: No summary available. Gene Ontology: MF: Rab geranylgeranyltransferase activity, prenyltransferase activity, protein prenyltransferase activity Pathways: UniProt: Q8C3P5, A...
Does Knockout of Akt1 in Microglial Cell Line causally result in response to virus?
1
2,429
Knockout
Akt1
response to virus
Microglial Cell Line
Gene: Akt1 (thymoma viral proto-oncogene 1) Type: protein-coding Summary: This gene encodes the founding member of the Akt serine-threonine protein kinase gene family that also includes Akt2 and Akt3. This kinase is a major downstream effector of the phosphatidylinositol 3-kinase (PI3K) pathway that med...
Does Knockout of Prl8a8 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
165
Knockout
Prl8a8
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Prl8a8 (prolactin family 8, subfamily a, member 81) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell surface receptor signaling pathway, female pregnancy, mammary gland development, positive regulation of lactation, positive regulation of receptor signaling path...
Does Knockout of Nup54 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Nup54
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Nup54 (nucleoporin 54) Type: protein-coding Summary: No summary available. Gene Ontology: BP: NLS-bearing protein import into nucleus, mRNA transport, nuclear pore organization, nucleocytoplasmic transport, protein localization to nuclear inner membrane, protein targeting, protein transpo...
Does Knockout of Pprc1 in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Pprc1
cell proliferation
Colonic Cancer Cell Line
Gene: Pprc1 (peroxisome proliferative activated receptor, gamma, coactivator-related 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: energy homeostasis, positive regulation of transcription by RNA polymerase II; MF: RNA binding, nucleic acid binding, transcription coac...
Does Knockout of Nelfa in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,265
Knockout
Nelfa
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Nelfa (negative elongation factor complex member A, Whsc2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of transcription elongation by RNA polymerase II, positive regulation of transcription by RNA polymerase II; MF: chromatin binding, molecul...
Does Knockout of Brca1 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,289
Knockout
Brca1
cell proliferation
Mouse kidney carcinoma cell
Gene: Brca1 (breast cancer 1, early onset) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA recombination, DNA repair, DNA strand resection involved in replication fork processing, cellular response to indole-3-methanol, cellular response to ionizi...
Does Knockout of Lrr1 in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Lrr1
cell proliferation
Colonic Cancer Cell Line
Gene: Lrr1 (leucine rich repeat protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: intracellular signal transduction, protein ubiquitination Pathways: Adaptive Immune System, Antigen processing: Ubiquitination & Proteasome degradation, Class I MHC mediate...
Does Knockout of Zkscan4 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
1,130
Knockout
Zkscan4
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Zkscan4 (zinc finger with KRAB and SCAN domains 4) Type: protein-coding Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and identical protein binding activity. Predic...
Does Knockout of Edf1 in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Edf1
protein/peptide distribution
myoblast cell line
Gene: Edf1 (endothelial differentiation-related factor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, positive regulation of DNA-templated transcription; MF: DNA binding, TFIID-class transcription factor complex binding, calmodulin binding, trans...
Does Knockout of Isoc2a in Melanoma Cell Line causally result in cell proliferation?
0
2,492
Knockout
Isoc2a
cell proliferation
Melanoma Cell Line
Gene: Isoc2a (isochorismatase domain containing 2a) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cytoplasm, mitochondrion, nucleus Pathways: UniProt: P85094 Entrez ID: 664994
Does Knockout of Ddit3 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
1,130
Knockout
Ddit3
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Ddit3 (DNA-damage inducible transcript 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ER overload response, GDF15-GFRAL signaling pathway, HRI-mediated signaling, Wnt signaling pathway, anterior/posterior axis specification, apoptotic process, artery development...
Does Knockout of Cdk7 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Cdk7
protein/peptide distribution
myoblast cell line
Gene: Cdk7 (cyclin dependent kinase 7) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, RNA polymerase II promoter clearance, RNA polymerase II transcription initiation surveillance, cell division, positive regulation of transcription by RN...
Does Knockout of Bicd2 in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
Bicd2
protein/peptide accumulation
Mouse cell
Gene: Bicd2 (BICD cargo adaptor 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: centrosome localization, mRNA transport, microtubule anchoring at microtubule organizing center, microtubule-based movement, minus-end-directed organelle transport along microtubule, protei...
Does Knockout of Tap2 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in cell proliferation?
1
2,141
Knockout
Tap2
cell proliferation
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Tap2 (transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)) Type: protein-coding Summary: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular...
Does Knockout of Apoc2 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
Apoc2
protein/peptide accumulation
Embryonic Cell Line
Gene: Apoc2 (apolipoprotein C2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cholesterol efflux, chylomicron remnant clearance, chylomicron remodeling, high-density lipoprotein particle clearance, lipid catabolic process, lipid metabolic process, lipid transport, lipop...
Does Knockout of Zc2hc1b in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Zc2hc1b
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Zc2hc1b (zinc finger, C2HC-type containing 1B) Type: protein-coding Summary: Predicted to enable zinc ion binding activity. Orthologous to human ZC2HC1B (zinc finger C2HC-type containing 1B). [provided by Alliance of Genome Resources, Jul 2025] Gene Ontology: MF: metal ion binding, molecu...
Does Knockout of Rhoj in macrophage causally result in phagocytosis?
0
1,888
Knockout
Rhoj
phagocytosis
macrophage
Gene: Rhoj (ras homolog family member J) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Rho protein signal transduction, actin cytoskeleton organization, actin filament organization, angiogenesis, endocytosis, establishment of cell polarity, positive regulation of cell m...
Does Knockout of Mrpl42 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,265
Knockout
Mrpl42
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Mrpl42 (mitochondrial ribosomal protein L42) Type: protein-coding Summary: No summary available. Gene Ontology: CC: mitochondrial inner membrane, mitochondrial large ribosomal subunit, mitochondrial small ribosomal subunit, mitochondrion, plasma membrane, ribonucleoprotein complex, riboso...
Does Knockout of Serpinf2 in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Serpinf2
protein/peptide distribution
Microglial Cell Line
Gene: Serpinf2 (serine (or cysteine) peptidase inhibitor, clade F, member 2) Type: protein-coding Summary: Predicted to enable protease binding activity; protein homodimerization activity; and serine-type endopeptidase inhibitor activity. Involved in several processes, including collagen fibril organiza...
Does Knockout of Sema4c in Regulatory T cell causally result in cell proliferation?
0
2,127
Knockout
Sema4c
cell proliferation
Regulatory T cell
Gene: Sema4c (sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C) Type: protein-coding Summary: This gene encodes a member of the semaphorin family of proteins that have diverse functions in neuronal development, heart morphogenesis, vascular...
Does Knockout of Psme3 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Psme3
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Psme3 (proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki)) Type: protein-coding Summary: Predicted to enable several functions, including MDM2/MDM4 family protein binding activity; endopeptidase activator activity; and p53 binding activity. Predicted to be involved in negative r...
Does Knockout of Mplkip in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
Mplkip
response to virus
Embryonic Fibroblast Cell Line
Gene: Mplkip (M-phase specific PLK1 intereacting protein) Type: protein-coding Summary: No summary available. Gene Ontology: CC: Golgi apparatus, centrosome, cytoplasm, cytoskeleton, midbody, nucleoplasm, nucleus Pathways: UniProt: Q9D011 Entrez ID: 66308
Does Knockout of Eva1a in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,275
Knockout
Eva1a
cell proliferation
Colonic Cancer Cell Line
Gene: Eva1a (eva-1 homolog A, regulator of programmed cell death) Type: protein-coding Summary: No summary available. Gene Ontology: BP: TOR signaling, apoptotic process, autophagy, biological_process, cardiac left ventricle morphogenesis, connective tissue replacement, energy reserve metabolic...
Does Knockout of Supt7l in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Supt7l
cell proliferation
Colonic Cancer Cell Line
Gene: Supt7l (SPT7-like, STAGA complex gamma subunit) Type: protein-coding Summary: No summary available. Gene Ontology: BP: maintenance of protein location in nucleus, positive regulation of DNA-templated transcription, regulation of DNA repair, regulation of RNA splicing; MF: protein heterodi...
Does Knockout of Stx17 in Immortal mouse chromaffin cells causally result in cell viability?
0
2,469
Knockout
Stx17
cell viability
Immortal mouse chromaffin cells
Gene: Stx17 (syntaxin 17) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Golgi organization, autophagosome maturation, autophagosome membrane docking, autophagosome-lysosome fusion, autophagy, endoplasmic reticulum to Golgi vesicle-mediated transport, endoplasmic reticul...
Does Knockout of Top2b in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Top2b
protein/peptide distribution
myoblast cell line
Gene: Top2b (topoisomerase (DNA) II beta) Type: protein-coding Summary: No summary available. Gene Ontology: BP: B cell differentiation, DNA metabolic process, DNA topological change, axonogenesis, cellular response to ATP, cellular response to hydrogen peroxide, cellular senescence, forebrain ...
Does Knockout of Plpp1 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Plpp1
protein/peptide distribution
myoblast cell line
Gene: Plpp1 (phospholipid phosphatase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ceramide metabolic process, diacylglycerol biosynthetic process, lipid metabolic process, phospholipid dephosphorylation, phospholipid metabolic process, signal transduction, sphingos...
Does Knockout of Usp25 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Usp25
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Usp25 (ubiquitin specific peptidase 25) Type: protein-coding Summary: Predicted to enable SUMO binding activity; cysteine-type deubiquitinase activity; and enzyme binding activity. Involved in several processes, including interleukin-17-mediated signaling pathway; intracellular signal transduction...
Does Knockout of Ano1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
82
Knockout
Ano1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Ano1 (anoctamin 1, calcium activated chloride channel) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to heat, cellular response to peptide, chloride transmembrane transport, chloride transport, detection of mechanical stimulus involved in sensory...
Does Knockout of Ndufa2 in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Ndufa2
cell proliferation
Melanoma Cell Line
Gene: Ndufa2 (NADH:ubiquinone oxidoreductase subunit A2) Type: protein-coding Summary: This gene encodes a subunit of the NADH-ubiquinone oxidoreductase (complex I) enzyme, which is a large, multimeric protein. It is the first enzyme complex in the mitochondrial electron transport chain and catalyzes th...
Does Knockout of Crtc2 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
165
Knockout
Crtc2
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Crtc2 (CREB regulated transcription coactivator 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to cAMP, gluconeogenesis, glucose homeostasis, positive regulation of CREB transcription factor activity, positive regulation of transcription by RNA...
Does Knockout of Lama4 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Lama4
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Lama4 (laminin, alpha 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: blood vessel development, brown fat cell differentiation, cell adhesion, negative regulation of cold-induced thermogenesis, regulation of cell adhesion, regulation of cell migration, regulation...
Does Knockout of Gins1 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Gins1
cell proliferation
Embryonic Stem Cell Line
Gene: Gins1 (GINS complex subunit 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA replication, DNA strand elongation involved in mitotic DNA replication, inner cell mass cell proliferation; CC: CMG complex, GINS complex, chromosome, cytoplasm, nucleus Path...
Does Knockout of Pbx2 in breast epithelium causally result in cell cycle progression?
0
1,470
Knockout
Pbx2
cell cycle progression
breast epithelium
Gene: Pbx2 (pre B cell leukemia homeobox 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: animal organ morphogenesis, brain development, embryonic limb morphogenesis, embryonic organ development, eye development, neuron development, positive regulation of transcription ...
Does Knockout of Ankrd49 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Ankrd49
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Ankrd49 (ankyrin repeat domain 49) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, positive regulation of DNA-templated transcription, spermatogenesis Pathways: UniProt: Q8VE42 Entrez ID: 56503
Does Knockout of Slc15a4 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,280
Knockout
Slc15a4
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Slc15a4 (solute carrier family 15, member 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: L-histidine transmembrane export from vacuole, dipeptide import across plasma membrane, histidine transport, immune system process, innate immune response, mast cell homeost...
Does Knockout of A630076J17Rik in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,262
Knockout
A630076J17Rik
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: A630076J17Rik (RIKEN cDNA A630076J17 gene) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID: 319929
Does Knockout of Xrn2 in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Xrn2
cell proliferation
Melanoma Cell Line
Gene: Xrn2 (5'-3' exoribonuclease 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA recombination, DNA repair, DNA-templated transcription termination, RNA metabolic process, hippocampus development, mRNA processing, microtubule-based process, neuron differentiation,...
Does Knockout of Rilpl1 in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Rilpl1
protein/peptide distribution
Microglial Cell Line
Gene: Rilpl1 (Rab interacting lysosomal protein-like 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cilium assembly, epithelial cell morphogenesis, nitric oxide mediated signal transduction, protein transport, protein transport from ciliary membrane to plasma membrane...
Does Knockout of Idi1 in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Idi1
cell proliferation
Melanoma Cell Line
Gene: Idi1 (isopentenyl-diphosphate delta isomerase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cholesterol biosynthetic process, cholesterol biosynthetic process via desmosterol, cholesterol biosynthetic process via lathosterol, cholesterol metabolic process, dimeth...
Does Knockout of Alkbh6 in Melanoma Cell Line causally result in cell proliferation?
0
2,492
Knockout
Alkbh6
cell proliferation
Melanoma Cell Line
Gene: Alkbh6 (alkB homolog 6) Type: protein-coding Summary: No summary available. Gene Ontology: MF: 2-oxoglutarate-dependent dioxygenase activity, dioxygenase activity, metal ion binding, oxidoreductase activity; CC: cytoplasm, focal adhesion, nucleoplasm, nucleus Pathways: ...
Does Knockout of Accsl in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Accsl
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Accsl (1-aminocyclopropane-1-carboxylate synthase (inactive)-like) Type: protein-coding Summary: Predicted to enable transaminase activity. Predicted to be involved in amino acid metabolic process. Orthologous to human ACCSL (1-aminocyclopropane-1-carboxylate synthase homolog (inactive) like). [pr...
Does Knockout of Tspear in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Tspear
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Tspear (thrombospondin type laminin G domain and EAR repeats) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Notch signaling pathway, hair cycle process, regulation of Notch signaling pathway, sensory perception of sound, signal transduction, tooth mineralization; ...
Does Knockout of Myo16 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Myo16
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Myo16 (myosin XVI) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cerebellum development, negative regulation of G1/S transition of mitotic cell cycle, negative regulation of cell population proliferation, neuron projection morphogenesis, phosphatidylinositol 3-kin...
Does Knockout of Recql4 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,267
Knockout
Recql4
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Recql4 (RecQ protein-like 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA recombination, DNA replication, chromosome organization, double-strand break repair via homologous recombination, negative regulation of sister chromatid cohesion, pigmentation, positiv...