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Does Knockout of Cdk2ap2 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,286
Knockout
Cdk2ap2
cell proliferation
Mouse kidney carcinoma cell
Gene: Cdk2ap2 (cyclin dependent kinase 2 associated protein 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of G1/S transition of mitotic cell cycle, regulation of microtubule cytoskeleton organization, regulation of stem cell division; CC: NuRD com...
Does Knockout of Ecscr in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,259
Knockout
Ecscr
cell proliferation
Mouse kidney carcinoma cell
Gene: Ecscr (endothelial cell surface expressed chemotaxis and apoptosis regulator) Type: protein-coding Summary: Acts upstream of or within negative regulation of angiogenesis. Located in cytosol and plasma membrane. Is expressed in several structures, including cardiovascular system; gut; hemolymphoid...
Does Knockout of Racgap1 in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,263
Knockout
Racgap1
cell proliferation
Colonic Cancer Cell Line
Gene: Racgap1 (Rac GTPase-activating protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Rho protein signal transduction, actomyosin contractile ring assembly, cell differentiation, cell division, erythrocyte differentiation, mitotic cytokinesis, mitotic spindle mi...
Does Knockout of Adhfe1 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,279
Knockout
Adhfe1
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Adhfe1 (alcohol dehydrogenase, iron containing, 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: L-glutamate catabolic process via 2-hydroxyglutarate, lipid metabolic process; MF: alcohol dehydrogenase (NAD+) activity, hydroxyacid-oxoacid transhydrogenase activity...
Does Knockout of Zfp617 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,280
Knockout
Zfp617
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Zfp617 (zinc finger protein 617) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of transcription by RNA polymerase II, regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II; MF: DNA binding, DNA-binding tran...
Does Knockout of Magee2 in Microglial Cell Line causally result in protein/peptide accumulation?
0
1,399
Knockout
Magee2
protein/peptide accumulation
Microglial Cell Line
Gene: Magee2 (MAGE family member E2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: brain development, brain morphogenesis, negative regulation of transcription by RNA polymerase II Pathways: UniProt: Q8CBC3, Q52KG3 Entrez ID: 272790
Does Knockout of Plekhj1 in Regulatory T cell causally result in cell proliferation?
0
1,484
Knockout
Plekhj1
cell proliferation
Regulatory T cell
Gene: Plekhj1 (pleckstrin homology domain containing, family J member 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: endosome organization, receptor recycling, retrograde transport, endosome to Golgi; CC: cytosol, early endosome, recycling endosome, trans-Golgi networ...
Does Knockout of Fhit in Melanoma Cell Line causally result in cell proliferation?
0
1,282
Knockout
Fhit
cell proliferation
Melanoma Cell Line
Gene: Fhit (fragile histidine triad gene) Type: protein-coding Summary: This gene encodes a member of the HIT family of proteins that are characterized by the presence of a histidine triad sequence. The encoded protein is a diadenosine triphosphate hydrolase enzyme that cleaves the P(1)-P(3)-bis(5'-aden...
Does Knockout of Dmd in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,263
Knockout
Dmd
cell proliferation
Colonic Cancer Cell Line
Gene: Dmd (dystrophin, muscular dystrophy) Type: protein-coding Summary: This gene encodes a large, rod-like cytoskeletal protein which is found at the inner surface of muscle fibers in skeletal and cardiac muscles. The encoded protein, dystrophin, is part of the dystrophin-glycoprotein complex, which b...
Does Knockout of Sh2d2a in macrophage causally result in phagocytosis?
0
1,888
Knockout
Sh2d2a
phagocytosis
macrophage
Gene: Sh2d2a (SH2 domain containing 2A) Type: protein-coding Summary: Predicted to enable protein-macromolecule adaptor activity. Acts upstream of or within T cell proliferation. Predicted to be located in plasma membrane. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in...
Does Knockout of 1700013G24Rik in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
687
Knockout
1700013G24Rik
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: 1700013G24Rik (RIKEN cDNA 1700013G24 gene) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q9DAC6 Entrez ID: 69380
Does Knockout of Pabpn1l in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
161
Knockout
Pabpn1l
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Pabpn1l (poly(A)binding protein nuclear 1-like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: maternal-to-zygotic transition of gene expression, negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process, negative regulation of protein ...
Does Knockout of Aamp in breast epithelium causally result in cell cycle progression?
0
1,470
Knockout
Aamp
cell cycle progression
breast epithelium
Gene: Aamp (angio-associated migratory protein) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cell surface, cytoplasm, intercellular bridge, microtubule cytoskeleton, plasma membrane Pathways: Hemostasis, Immune System, Innate Immune System, NOD1/2 Signaling Pa...
Does Knockout of Flii in Melanoma Cell Line causally result in cell proliferation?
0
1,282
Knockout
Flii
cell proliferation
Melanoma Cell Line
Gene: Flii (flightless I actin binding protein) Type: protein-coding Summary: This gene encodes a protein with gelsolin-like repeats and an N-terminal leucine-rich repeat domain. The protein is similar to a Drosophila protein involved in early embryogenesis and the structural organization of indirect fl...
Does Knockout of Efcab5 in myoblast cell line causally result in protein/peptide distribution?
0
1,682
Knockout
Efcab5
protein/peptide distribution
myoblast cell line
Gene: Efcab5 (EF-hand calcium binding domain 5) Type: protein-coding Summary: No summary available. Gene Ontology: MF: calcium ion binding, metal ion binding, molecular_function Pathways: UniProt: A0JP43 Entrez ID: 319634
Does Knockout of Arsa in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Arsa
protein/peptide distribution
Microglial Cell Line
Gene: Arsa (arylsulfatase A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: autophagy, binding of sperm to zona pellucida, lipid metabolic process, response to estrogen, response to ethanol, response to methylmercury, response to nutrient, response to pH; MF: arylsulfata...
Does Knockout of Zc3hc1 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,262
Knockout
Zc3hc1
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Zc3hc1 (zinc finger, C3HC type 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell division, protein ubiquitination; MF: metal ion binding, protein kinase binding, zinc ion binding; CC: nuclear envelope, nuclear membrane, nuclear pore nuclear basket, nucleoplasm...
Does Knockout of Yrdc in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
Yrdc
protein/peptide accumulation
Mouse cell
Gene: Yrdc (yrdC domain containing (E.coli)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of transport, regulation of translational fidelity, tRNA threonylcarbamoyladenosine modification; MF: L-threonylcarbamoyladenylate synthase, double-stranded RN...
Does Knockout of Rasef in myoblast cell line causally result in protein/peptide distribution?
0
1,679
Knockout
Rasef
protein/peptide distribution
myoblast cell line
Gene: Rasef (RAS and EF hand domain containing) Type: protein-coding Summary: No summary available. Gene Ontology: BP: vesicle-mediated transport, zymogen granule exocytosis; MF: GDP binding, GTP binding, GTPase activity, identical protein binding, nucleotide binding; CC: Golgi apparatus, cytop...
Does Knockout of 2300009A05Rik in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
167
Knockout
2300009A05Rik
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: 2300009A05Rik (RIKEN cDNA 2300009A05 gene) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cellular_component, extracellular region Pathways: UniProt: Q0VG49 Entrez ID: 69478
Does Knockout of Mtfmt in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Mtfmt
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Mtfmt (mitochondrial methionyl-tRNA formyltransferase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: conversion of methionyl-tRNA to N-formyl-methionyl-tRNA, translation, translational initiation; MF: methionyl-tRNA formyltransferase activity, transferase activity...
Does Knockout of Cdkn2b in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Cdkn2b
cell viability
Immortal mouse chromaffin cells
Gene: Cdkn2b (cyclin dependent kinase inhibitor 2B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to cell-matrix adhesion, cellular response to nutrient, cellular senescence, megakaryocyte differentiation, negative regulation of G1/S transition of mito...
Does Knockout of Ndufaf8 in Melanoma Cell Line causally result in cell proliferation?
0
1,269
Knockout
Ndufaf8
cell proliferation
Melanoma Cell Line
Gene: Ndufaf8 (NADH:ubiquinone oxidoreductase complex assembly factor 8) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial respiratory chain complex I assembly; CC: mitochondrial matrix, mitochondrion Pathways: Aerobic respiration and respiratory elec...
Does Knockout of Gfra2 in Colonic Cancer Cell Line causally result in tumorigenicity?
0
2,181
Knockout
Gfra2
tumorigenicity
Colonic Cancer Cell Line
Gene: Gfra2 (glial cell line derived neurotrophic factor family receptor alpha 2) Type: protein-coding Summary: The protein encoded by this gene is part of the receptor complex that transduces glial cell-derived neurotrophic factor and neurturin signals by mediating autophosphorylation and activation of...
Does Knockout of Lrrc4 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
81
Knockout
Lrrc4
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Lrrc4 (leucine rich repeat containing 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: excitatory synapse assembly, modulation of chemical synaptic transmission, postsynaptic density protein 95 clustering, synapse organization, synaptic membrane adhesion; MF: cell...
Does Knockout of Nphs1 in Melanoma Cell Line causally result in cell proliferation?
0
1,269
Knockout
Nphs1
cell proliferation
Melanoma Cell Line
Gene: Nphs1 (nephrosis 1, nephrin) Type: protein-coding Summary: No summary available. Gene Ontology: BP: JNK cascade, MAPK cascade, cell adhesion, cell-cell adhesion, gene expression, glomerular basement membrane development, muscle organ development, myoblast fusion, podocyte development, pos...
Does Knockout of Zeb2 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
165
Knockout
Zeb2
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Zeb2 (zinc finger E-box binding homeobox 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: astrocyte activation, cell proliferation in forebrain, central nervous system development, collateral sprouting, corpus callosum morphogenesis, corticospinal tract morphogene...
Does Knockout of Kcnb1 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,261
Knockout
Kcnb1
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Kcnb1 (potassium voltage gated channel, Shab-related subfamily, member 1) Type: protein-coding Summary: Enables delayed rectifier potassium channel activity. Involved in several processes, including cellular response to glucose stimulus; negative regulation of insulin secretion; and positive regul...
Does Knockout of Krtap19-4 in Melanoma Cell Line causally result in cell proliferation?
0
2,488
Knockout
Krtap19-4
cell proliferation
Melanoma Cell Line
Gene: Krtap19-4 (keratin associated protein 19-4) Type: protein-coding Summary: Predicted to be located in cytosol and intermediate filament. Orthologous to human KRTAP19-3 (keratin associated protein 19-3). [provided by Alliance of Genome Resources, Jul 2025] Gene Ontology: CC: cellular_compon...
Does Knockout of Fgf15 in Regulatory T cell causally result in cell proliferation?
0
1,484
Knockout
Fgf15
cell proliferation
Regulatory T cell
Gene: Fgf15 (fibroblast growth factor 15) Type: protein-coding Summary: No summary available. Gene Ontology: BP: fibroblast growth factor receptor signaling pathway, heart development, negative regulation of bile acid biosynthetic process, negative regulation of gene expression, neural crest ce...
Does Knockout of 2310057J18Rik in Microglial Cell Line causally result in response to virus?
0
2,429
Knockout
2310057J18Rik
response to virus
Microglial Cell Line
Gene: 2310057J18Rik (RIKEN cDNA 2310057J18 gene) Type: protein-coding Summary: No summary available. Gene Ontology: CC: extracellular region, extracellular space Pathways: UniProt: Q8C6C9 Entrez ID: 67719
Does Knockout of Bckdha in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,152
Knockout
Bckdha
protein/peptide accumulation
Embryonic Cell Line
Gene: Bckdha (branched chain ketoacid dehydrogenase E1, alpha polypeptide) Type: protein-coding Summary: No summary available. Gene Ontology: BP: branched-chain alpha-keto acid decarboxylation to branched-chain acyl-CoA, branched-chain amino acid catabolic process; MF: branched-chain 2-oxo acid...
Does Knockout of Rnf182 in Microglial Cell Line causally result in response to virus?
0
2,429
Knockout
Rnf182
response to virus
Microglial Cell Line
Gene: Rnf182 (ring finger protein 182) Type: protein-coding Summary: No summary available. Gene Ontology: BP: protein ubiquitination; MF: metal ion binding, transferase activity, ubiquitin protein ligase activity, ubiquitin-protein transferase activity, zinc ion binding; CC: cytoplasm, membrane...
Does Knockout of Tshb in renal medulla cell line causally result in response to bacteria?
0
2,049
Knockout
Tshb
response to bacteria
renal medulla cell line
Gene: Tshb (thyroid stimulating hormone, beta subunit) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cytoplasm, extracellular region, extracellular space Pathways: Autoimmune thyroid disease - Mus musculus (mouse), Neuroactive ligand-receptor interaction - Mus ...
Does Knockout of Zfp449 in Embryonic Stem Cell Line causally result in cell proliferation?
0
578
Knockout
Zfp449
cell proliferation
Embryonic Stem Cell Line
Gene: Zfp449 (zinc finger protein 449) Type: protein-coding Summary: No summary available. Gene Ontology: BP: regulation of transcription by RNA polymerase II, spermatogonial cell division; MF: DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, RNA polymerase II...
Does Knockout of Prl8a2 in macrophage causally result in phagocytosis?
0
1,888
Knockout
Prl8a2
phagocytosis
macrophage
Gene: Prl8a2 (prolactin family 8, subfamily a, member 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell surface receptor signaling pathway, female pregnancy, mammary gland development, maternal process involved in female pregnancy, positive regulation of lactation, ...
Does Knockout of Ccna1 in macrophage causally result in phagocytosis?
0
1,888
Knockout
Ccna1
phagocytosis
macrophage
Gene: Ccna1 (cyclin A1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G1/S transition of mitotic cell cycle, cell differentiation, cell division, meiotic cell cycle, spermatogenesis; MF: cyclin-dependent protein serine/threonine kinase regulator activity, protein bindin...
Does Knockout of Spata2 in Microglial Cell Line causally result in protein/peptide accumulation?
0
1,398
Knockout
Spata2
protein/peptide accumulation
Microglial Cell Line
Gene: Spata2 (spermatogenesis associated 2) Type: protein-coding Summary: Predicted to enable signaling receptor complex adaptor activity and ubiquitin-specific protease binding activity. Involved in protein linear deubiquitination; regulation of necroptotic process; and regulation of tumor necrosis fac...
Does Knockout of Slc6a6 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,286
Knockout
Slc6a6
cell proliferation
Mouse kidney carcinoma cell
Gene: Slc6a6 (solute carrier family 6 (neurotransmitter transporter, taurine), member 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: alanine transport, amino acid import across plasma membrane, amino acid transport, gamma-aminobutyric acid import, gamma-aminobutyric a...
Does Knockout of Metrnl in Melanoma Cell Line causally result in cell proliferation?
0
1,281
Knockout
Metrnl
cell proliferation
Melanoma Cell Line
Gene: Metrnl (meteorin, glial cell differentiation regulator-like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: brown fat cell differentiation, energy homeostasis, fat cell differentiation, negative regulation of inflammatory response, positive regulation of brown fat ...
Does Knockout of Rpl32 in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
Rpl32
protein/peptide accumulation
Regulatory T cell
Gene: Rpl32 (ribosomal protein L32) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to dexamethasone stimulus, cytoplasmic translation, liver regeneration, translation, translation at postsynapse, translation at presynapse; MF: structural constituent of ...
Does Knockout of Gtpbp3 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
84
Knockout
Gtpbp3
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Gtpbp3 (GTP binding protein 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial tRNA wobble uridine modification, tRNA methylation, tRNA modification, tRNA processing, tRNA wobble uridine modification; MF: GTP binding, GTPase activity, hydrolase activit...
Does Knockout of Zcchc13 in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Zcchc13
response to chemicals
Pancreatic Cancer Cell Line
Gene: Zcchc13 (zinc finger, CCHC domain containing 13) Type: protein-coding Summary: No summary available. Gene Ontology: MF: DNA binding, mRNA binding, metal ion binding, nucleic acid binding, single-stranded RNA binding, translation regulator activity, zinc ion binding; CC: cytoplasm, endopla...
Does Knockout of Snap29 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,271
Knockout
Snap29
cell proliferation
Mouse kidney carcinoma cell
Gene: Snap29 (synaptosomal-associated protein 29) Type: protein-coding Summary: No summary available. Gene Ontology: BP: autophagosome maturation, autophagosome membrane docking, autophagy, cell projection organization, cilium assembly, exocytosis, protein transport, regulation of synaptic vesi...
Does Knockout of Corin in Microglial Cell Line causally result in protein/peptide accumulation?
0
1,399
Knockout
Corin
protein/peptide accumulation
Microglial Cell Line
Gene: Corin (corin, serine peptidase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: female pregnancy, neuron differentiation, peptide hormone processing, proteolysis, regulation of blood pressure, regulation of renal sodium excretion, regulation of systemic arterial blo...
Does Knockout of Mtx1 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,268
Knockout
Mtx1
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Mtx1 (metaxin 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrion organization, protein transport; CC: SAM complex, membrane, mitochondrial inner membrane, mitochondrial outer membrane, mitochondrion Pathways: UniProt: D3Z3F4, Q8R5C0,...
Does Knockout of Fbln5 in breast epithelium causally result in cell cycle progression?
0
1,469
Knockout
Fbln5
cell cycle progression
breast epithelium
Gene: Fbln5 (fibulin 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell adhesion, elastic fiber assembly, extracellular matrix organization, intramembranous bone growth, negative regulation of angiogenesis, negative regulation of transcription by RNA polymerase II, p...
Does Knockout of 4933430I17Rik in Immortal mouse chromaffin cells causally result in cell viability?
0
2,469
Knockout
4933430I17Rik
cell viability
Immortal mouse chromaffin cells
Gene: 4933430I17Rik (RIKEN cDNA 4933430I17 gene) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q8BHW4, F6UZS4, Q14AX1 Entrez ID: 214106
Does Knockout of Cel in Embryonic Fibroblast Cell Line causally result in cell proliferation?
0
345
Knockout
Cel
cell proliferation
Embryonic Fibroblast Cell Line
Gene: Cel (carboxyl ester lipase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ceramide catabolic process, intestinal cholesterol absorption, lipid catabolic process, lipid metabolic process, pancreatic juice secretion, retinol metabolic process; MF: acetylesterase act...
Does Knockout of Rack1 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,262
Knockout
Rack1
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Rack1 (receptor for activated C kinase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, cellular response to glucose stimulus, cellular response to growth factor stimulus, gastrulation, intracellular protein localization, intracellular signal tr...
Does Knockout of Cox8a in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,264
Knockout
Cox8a
cell proliferation
Colonic Cancer Cell Line
Gene: Cox8a (cytochrome c oxidase subunit 8A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial electron transport, cytochrome c to oxygen, oxidative phosphorylation; CC: membrane, mitochondrial inner membrane, mitochondrial membrane, mitochondrion, respirator...
Does Knockout of Nfyc in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Nfyc
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Nfyc (nuclear transcription factor-Y gamma) Type: protein-coding Summary: Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Contributes to transcription cis-regulatory region binding ...
Does Knockout of Trim30a in Embryonic Fibroblast Cell Line causally result in cell proliferation?
0
345
Knockout
Trim30a
cell proliferation
Embryonic Fibroblast Cell Line
Gene: Trim30a (tripartite motif-containing 30A) Type: protein-coding Summary: Predicted to enable several functions, including protein homodimerization activity; transcription coactivator activity; and ubiquitin protein ligase activity. Involved in several processes, including negative regulation of cyt...
Does Knockout of Pla2g12b in Melanoma Cell Line causally result in protein/peptide accumulation?
0
1,839
Knockout
Pla2g12b
protein/peptide accumulation
Melanoma Cell Line
Gene: Pla2g12b (phospholipase A2, group XIIB) Type: protein-coding Summary: No summary available. Gene Ontology: BP: arachidonate secretion, cholesterol homeostasis, lipid catabolic process, low-density lipoprotein particle remodeling, phospholipid metabolic process, triglyceride homeostasis; M...
Does Knockout of Pim1 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,280
Knockout
Pim1
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Pim1 (proviral integration site 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, cellular detoxification, cellular response to amino acid starvation, cellular response to nutrient levels, cellular response to type II interferon, cytolysis in ano...
Does Knockout of Cep135 in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
Cep135
protein/peptide accumulation
Regulatory T cell
Gene: Cep135 (centrosomal protein 135) Type: protein-coding Summary: No summary available. Gene Ontology: BP: centriole replication, centriole-centriole cohesion, positive regulation of establishment of protein localization, positive regulation of non-motile cilium assembly; MF: identical prote...
Does Knockout of Epcam in breast epithelium causally result in cell cycle progression?
0
1,468
Knockout
Epcam
cell cycle progression
breast epithelium
Gene: Epcam (epithelial cell adhesion molecule) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell-cell adhesion, cell-cell adhesion via plasma-membrane adhesion molecules, negative regulation of apoptotic process, negative regulation of cell-cell adhesion mediated by c...
Does Knockout of Mif in pro-B-lymphocyte causally result in response to chemicals?
0
1,720
Knockout
Mif
response to chemicals
pro-B-lymphocyte
Gene: Mif (macrophage migration inhibitory factor (glycosylation-inhibiting factor)) Type: protein-coding Summary: Enables cytokine activity; phenylpyruvate tautomerase activity; and protease binding activity. Involved in several processes, including positive regulation of cytokine production; positive ...
Does Knockout of Atg16l1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
165
Knockout
Atg16l1
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Atg16l1 (autophagy related 16 like 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: autophagosome assembly, autophagy, axonal transport, corpus callosum development, defense response to virus, dendrite arborization, hippocampus development, macroautophagy, microau...
Does Knockout of Col4a2 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,152
Knockout
Col4a2
protein/peptide accumulation
Embryonic Cell Line
Gene: Col4a2 (collagen, type IV, alpha 2) Type: protein-coding Summary: This gene encodes the alpha-2 subunit of the type IV collagens, an essential component of basement membranes. The encoded protein forms a triple helical heterotrimer comprised of alpha-1 and alpha-2 subunits that assembles into a ty...
Does Knockout of Tcirg1 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,277
Knockout
Tcirg1
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Tcirg1 (T cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: B cell differentiation, T cell differentiation, T cell homeostasis, T-helper 1 cell activation, apoptotic process, autophagosome ass...
Does Knockout of Mmp9 in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
Mmp9
response to virus
Embryonic Fibroblast Cell Line
Gene: Mmp9 (matrix metallopeptidase 9) Type: protein-coding Summary: This gene encodes a member of the matrix metalloproteinase family of extracellular matrix-degrading enzymes that are involved in tissue remodeling, wound repair, progression of atherosclerosis and tumor invasion. The encoded preproprot...
Does Knockout of Gps2 in Immortal mouse chromaffin cells causally result in cell viability?
0
2,469
Knockout
Gps2
cell viability
Immortal mouse chromaffin cells
Gene: Gps2 (G protein pathway suppressor 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: B cell differentiation, negative regulation of B cell receptor signaling pathway, negative regulation of JNK cascade, negative regulation of fat cell differentiation, negative regu...
Does Knockout of Gpm6b in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,263
Knockout
Gpm6b
cell proliferation
Colonic Cancer Cell Line
Gene: Gpm6b (glycoprotein m6b) Type: protein-coding Summary: No summary available. Gene Ontology: BP: axon development, central nervous system myelination, extracellular matrix assembly, negative regulation of protein localization to cell surface, negative regulation of serotonin uptake, ossifi...
Does Knockout of Hinfp in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
Hinfp
protein/peptide accumulation
Mouse cell
Gene: Hinfp (histone H4 transcription factor) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage checkpoint signaling, DNA repair, DNA-templated transcription, G1/S transition of mitotic cell cycle, cell cycle G1/S phase transition, establishment of protein locali...
Does Knockout of Art2b in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,265
Knockout
Art2b
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Art2b (ADP-ribosyltransferase 2b) Type: protein-coding Summary: No summary available. Gene Ontology: MF: NAD+ nucleosidase activity, NAD+ poly-ADP-ribosyltransferase activity, NAD+-protein-arginine ADP-ribosyltransferase activity, glycosyltransferase activity, hydrolase activity, hydrolas...
Does Knockout of Park7 in Neuroblastoma Cell Line causally result in response to virus?
0
1,422
Knockout
Park7
response to virus
Neuroblastoma Cell Line
Gene: Park7 (Parkinson disease (autosomal recessive, early onset) 7) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, adult locomotory behavior, androgen receptor signaling pathway, autophagy, cellular detoxification of aldehyde, cellular d...
Does Knockout of Acaa1b in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
165
Knockout
Acaa1b
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Acaa1b (acetyl-Coenzyme A acyltransferase 1B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: alpha-linolenic acid metabolic process, bile acid metabolic process, fatty acid beta-oxidation, fatty acid beta-oxidation using acyl-CoA oxidase, fatty acid derivative bios...
Does Knockout of Syt8 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,272
Knockout
Syt8
cell proliferation
Mouse kidney carcinoma cell
Gene: Syt8 (synaptotagmin VIII) Type: protein-coding Summary: Enables calcium-dependent protein binding activity. Involved in acrosome reaction. Located in cytoplasm and vesicle. Is expressed in bladder. Orthologous to human SYT8 (synaptotagmin 8). [provided by Alliance of Genome Resources, Jul 2025] ...
Does Knockout of Slc39a10 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,287
Knockout
Slc39a10
cell proliferation
Mouse kidney carcinoma cell
Gene: Slc39a10 (solute carrier family 39 (zinc transporter), member 10) Type: protein-coding Summary: No summary available. Gene Ontology: BP: bicarbonate transport, epithelial to mesenchymal transition, intracellular monoatomic cation homeostasis, intracellular zinc ion homeostasis, metal ion ...
Does Knockout of Tars2 in breast epithelium causally result in cell cycle progression?
0
1,470
Knockout
Tars2
cell cycle progression
breast epithelium
Gene: Tars2 (threonyl-tRNA synthetase 2, mitochondrial (putative)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: aminoacyl-tRNA metabolism involved in translational fidelity, tRNA aminoacylation, tRNA aminoacylation for protein translation, threonyl-tRNA aminoacylation,...
Does Knockout of Ribc2 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,263
Knockout
Ribc2
cell proliferation
Colonic Cancer Cell Line
Gene: Ribc2 (RIB43A domain with coiled-coils 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, flagellated sperm motility; CC: axonemal A tubule inner sheath, axonemal microtubule, cell projection, cilium, cytoplasm, cytoskeleton, motile cilium, sperm...
Does Knockout of BC024139 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,152
Knockout
BC024139
protein/peptide accumulation
Embryonic Cell Line
Gene: BC024139 (cDNA sequence BC024139) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cytoplasm, cytoskeleton Pathways: UniProt: E9PXU3, Q8BVJ3, E9Q3A6 Entrez ID: 271278
Does Knockout of Ggcx in Melanoma Cell Line causally result in cell proliferation?
0
1,269
Knockout
Ggcx
cell proliferation
Melanoma Cell Line
Gene: Ggcx (gamma-glutamyl carboxylase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to insulin stimulus, glucose homeostasis, negative regulation of bone development, negative regulation of neurotransmitter secretion, negative regulation of testoster...
Does Knockout of Ube2dnl2 in myoblast cell line causally result in protein/peptide distribution?
0
1,685
Knockout
Ube2dnl2
protein/peptide distribution
myoblast cell line
Gene: Ube2dnl2 (ubiquitin-conjugating enzyme E2D N-terminal like 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: protein polyubiquitination, ubiquitin-dependent protein catabolic process; MF: ATP binding, nucleotide binding, transferase activity, ubiquitin conjugating ...
Does Knockout of Ces2h in renal medulla cell line causally result in response to bacteria?
0
2,049
Knockout
Ces2h
response to bacteria
renal medulla cell line
Gene: Ces2h (carboxylesterase 2H) Type: protein-coding Summary: No summary available. Gene Ontology: MF: carboxylesterase activity, carboxylic ester hydrolase activity, hydrolase activity Pathways: Drug metabolism - other enzymes - Mus musculus (mouse) UniProt: F6Z9B9 ...
Does Knockout of Ifne in Embryonic Stem Cell Line causally result in cell proliferation?
0
578
Knockout
Ifne
cell proliferation
Embryonic Stem Cell Line
Gene: Ifne (interferon epsilon) Type: protein-coding Summary: No summary available. Gene Ontology: BP: B cell activation involved in immune response, T cell activation involved in immune response, adaptive immune response, defense response, defense response to bacterium, defense response to vir...
Does Knockout of Tax1bp3 in Mouse Embryonic Stem Cell causally result in protein/peptide accumulation?
0
1,077
Knockout
Tax1bp3
protein/peptide accumulation
Mouse Embryonic Stem Cell
Gene: Tax1bp3 (Tax1 (human T cell leukemia virus type I) binding protein 3) Type: protein-coding Summary: Enables beta-catenin binding activity. Involved in negative regulation of Wnt signaling pathway. Acts upstream of or within negative regulation of cell population proliferation. Located in cytoplasm...
Does Knockout of Asxl2 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Asxl2
protein/peptide distribution
myoblast cell line
Gene: Asxl2 (ASXL transcriptional regulator 2) Type: protein-coding Summary: This gene encodes a homolog of the Drosophila Asx gene, which interacts with genes involved in axial patterning. Mice with mutations in this gene display abnormal patterning of the axial skeleton, suggesting a similar function ...
Does Knockout of Cog2 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,274
Knockout
Cog2
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Cog2 (component of oligomeric golgi complex 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Golgi organization, glycosylation, intra-Golgi vesicle-mediated transport, protein transport, retrograde transport, vesicle recycling within Golgi; MF: protein-containing ...
Does Knockout of Chga in macrophage causally result in phagocytosis?
0
1,890
Knockout
Chga
phagocytosis
macrophage
Gene: Chga (chromogranin A) Type: protein-coding Summary: This gene encodes a member of the granin family of acidic secretory glycoproteins that are expressed in endocrine cells and neurons. The encoded preproprotein undergoes proteolytic processing to generate multiple functions peptides including panc...
Does Knockout of Umod in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Umod
response to chemicals
Pancreatic Cancer Cell Line
Gene: Umod (uromodulin) Type: protein-coding Summary: This gene encodes a glycoprotein that is the most abundant protein in mammalian urine under physiological conditions. It is synthesized in the kidney as a glycosyl-phosphatidylinositol anchored protein and released into urine as a soluble form by pro...
Does Knockout of Cep170b in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,280
Knockout
Cep170b
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Cep170b (centrosomal protein 170B) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cellular_component, cytoplasm, cytoskeleton, microtubule Pathways: UniProt: Q80U49 Entrez ID: 217882
Does Knockout of Apba3 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,266
Knockout
Apba3
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Apba3 (amyloid beta precursor protein binding family A member 3) Type: protein-coding Summary: Predicted to enable amyloid-beta binding activity; enzyme binding activity; and enzyme inhibitor activity. Acts upstream of or within chemical synaptic transmission; in utero embryonic development; and r...
Does Knockout of Hepacam2 in Regulatory T cell causally result in cell proliferation?
0
1,483
Knockout
Hepacam2
cell proliferation
Regulatory T cell
Gene: Hepacam2 (HEPACAM family member 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell division, centrosome cycle; CC: Golgi apparatus, Golgi membrane, centrosome, cytoplasm, cytoskeleton, membrane, midbody, mitotic spindle, nucleoplasm, spindle Pathways: ...
Does Knockout of Vmn2r105 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,289
Knockout
Vmn2r105
cell proliferation
Mouse kidney carcinoma cell
Gene: Vmn2r105 (vomeronasal 2, receptor 105) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, signal transduction; MF: G protein-coupled receptor activity; CC: membrane, plasma membrane Pathways: UniProt: A0A...
Does Knockout of Vmn2r1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,283
Knockout
Vmn2r1
cell proliferation
Mouse kidney carcinoma cell
Gene: Vmn2r1 (vomeronasal 2, receptor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, detection of chemical stimulus involved in sensory perception of smell, neuron differentiation, response to pheromone, signal transductio...
Does Knockout of Icos in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
Icos
response to virus
Embryonic Fibroblast Cell Line
Gene: Icos (inducible T cell co-stimulator) Type: protein-coding Summary: No summary available. Gene Ontology: BP: T cell costimulation, T cell tolerance induction, T follicular helper cell differentiation, cell-cell adhesion; MF: protein binding, signaling receptor activity; CC: external side ...
Does Knockout of Myo16 in Embryonic Stem Cell Line causally result in cell proliferation?
0
578
Knockout
Myo16
cell proliferation
Embryonic Stem Cell Line
Gene: Myo16 (myosin XVI) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cerebellum development, negative regulation of G1/S transition of mitotic cell cycle, negative regulation of cell population proliferation, neuron projection morphogenesis, phosphatidylinositol 3-kin...
Does Knockout of Mrpl14 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
1
2,307
Knockout
Mrpl14
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Mrpl14 (mitochondrial ribosomal protein L14) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial translation, translation; CC: mitochondrial inner membrane, mitochondrial large ribosomal subunit, mitochondrion, ribonucleoprotein complex, ribosome ...
Does Knockout of Ruvbl2 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
163
Knockout
Ruvbl2
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Ruvbl2 (RuvB-like AAA ATPase 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA recombination, DNA repair, box C/D snoRNP assembly, cellular response to UV, cellular response to estradiol stimulus, chromatin organization, chromatin remodelin...
Does Knockout of Slc27a5 in Colonic Cancer Cell Line causally result in tumorigenicity?
0
2,180
Knockout
Slc27a5
tumorigenicity
Colonic Cancer Cell Line
Gene: Slc27a5 (solute carrier family 27 (fatty acid transporter), member 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: bile acid biosynthetic process, bile acid metabolic process, establishment of localization in cell, fatty acid metabolic process, fatty acid transpo...
Does Knockout of Ghrh in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
84
Knockout
Ghrh
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Ghrh (growth hormone releasing hormone) Type: protein-coding Summary: This gene encodes a hormone that has stimulatory effects on pituitary growth hormone synthesis and release, and somatotrope expansion. The encoded preproprotein undergoes proteolytic processing to generate the mature peptide tha...
Does Knockout of Prss3 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
81
Knockout
Prss3
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Prss3 (serine protease 3) Type: protein-coding Summary: Enables serine-type peptidase activity. Predicted to be involved in proteolysis. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in pancreatitis. Orthol...
Does Knockout of Slc5a10 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
1,130
Knockout
Slc5a10
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Slc5a10 (solute carrier family 5 (sodium/glucose cotransporter), member 10) Type: protein-coding Summary: No summary available. Gene Ontology: BP: carbohydrate transmembrane transport, fructose transmembrane transport, hexose transmembrane transport, mannose transmembrane transport, monoa...
Does Knockout of Adrm1 in macrophage causally result in phagocytosis?
0
1,890
Knockout
Adrm1
phagocytosis
macrophage
Gene: Adrm1 (adhesion regulating molecule 1 26S proteasome ubiquitin receptor) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Sertoli cell development, adipose tissue development, follicle-stimulating hormone signaling pathway, oogenesis, ovarian follicle development, po...
Does Knockout of Txnrd1 in Regulatory T cell causally result in protein/peptide accumulation?
0
1,481
Knockout
Txnrd1
protein/peptide accumulation
Regulatory T cell
Gene: Txnrd1 (thioredoxin reductase 1) Type: protein-coding Summary: The protein encoded by this gene belongs to the pyridine nucleotide-disulfide oxidoreductase family, and is a member of the thioredoxin (Trx) system. Three thioredoxin reductase (TrxR) isozymes are found in mammals. TrxRs are selenocys...
Does Knockout of Retnlb in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,260
Knockout
Retnlb
cell proliferation
Mouse kidney carcinoma cell
Gene: Retnlb (resistin like beta) Type: protein-coding Summary: No summary available. Gene Ontology: BP: response to bacterium, signal transduction; CC: extracellular region, extracellular space Pathways: UniProt: Q99P86 Entrez ID: 57263
Does Knockout of Gps2 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,261
Knockout
Gps2
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Gps2 (G protein pathway suppressor 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: B cell differentiation, negative regulation of B cell receptor signaling pathway, negative regulation of JNK cascade, negative regulation of fat cell differentiation, negative regu...
Does Knockout of Ndst3 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Ndst3
cell proliferation
Mouse kidney carcinoma cell
Gene: Ndst3 (N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3) Type: protein-coding Summary: Enables N-acetylglucosamine deacetylase activity and heparan sulfate N-sulfotransferase activity. Involved in heparan sulfate proteoglycan biosynthetic process. Predicted to be located in Golgi membrane...