uuid stringlengths 4 8 | template_uuid stringclasses 40 values | question stringlengths 13 193 | answer stringlengths 29 2.2k | benchmark_query stringlengths 138 627 | execution_results stringlengths 2 1.14M | query_type stringclasses 2 values | sql_category stringclasses 26 values | bio_category stringclasses 14 values |
|---|---|---|---|---|---|---|---|---|
Q11.1502 | Q11 | Are there any VAMP3 SNPs that have a statistically significant adjusted SMR p-value in association with Parkinson's Disease and what tissues are they significant in? | No, based on the Whole Brain, Whole Blood, Cortex, Caudate Basal Ganglia, Skeletal Muscle, Hippocampus and Multi Ancestry Whole Brain samples tested there are no SNPs within the gene VAMP3 that are significantly associated with Parkinson's Disease. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'VAMP3' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.370 | Q11 | Are there any RP11-421M1.8 SNPs that have a statistically significant adjusted SMR p-value in association with Frontotemporal Dementia and what tissues are they significant in? | No, based on the Whole Brain, Whole Blood, Frontal Cortex, Cerebellar Hemisphere, Prefrontal Cortex, Cortex, Caudate Basal Ganglia, Tibial Nerve, Hypothalamus, Cerebellum and Nucleus Accumbens Basal samples tested there are no SNPs within the gene RP11-421M1.8 that are significantly associated with Frontotemporal Dementia. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'FTD' AND Gene = 'RP11-421M1.8' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.1009 | Q11 | Are there any RP1-266L20.9 SNPs that have a statistically significant adjusted SMR p-value in association with Lewy Body Dementia and what tissues are they significant in? | No, based on the Whole Blood samples tested there are no SNPs within the gene RP1-266L20.9 that are significantly associated with Lewy Body Dementia. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'LBD' AND Gene = 'RP1-266L20.9' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.1239 | Q11 | Are there any POLR3B SNPs that have a statistically significant adjusted SMR p-value in association with Progressive supranuclear palsy and what tissues are they significant in? | No, based on the Whole Brain, Skeletal Muscle and Whole Blood samples tested there are no SNPs within the gene POLR3B that are significantly associated with Progressive supranuclear palsy. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'POLR3B' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.595 | Q11 | Are there any TBX10 SNPs that have a statistically significant adjusted SMR p-value in association with Alzheimer's Disease and what tissues are they significant in? | No, based on the Cerebellum, Whole Brain and Whole Blood samples tested there are no SNPs within the gene TBX10 that are significantly associated with Alzheimer's Disease. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'TBX10' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.728 | Q11 | Are there any TOB1-AS1 SNPs that have a statistically significant adjusted SMR p-value in association with Progressive supranuclear palsy and what tissues are they significant in? | No, based on the Cortex, Caudate Basal Ganglia, Tibial Nerve, Skeletal Muscle, Multi Ancestry Whole Brain, Whole Blood, Whole Brain, Cerebellum and Nucleus Accumbens Basal samples tested there are no SNPs within the gene TOB1-AS1 that are significantly associated with Progressive supranuclear palsy. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'TOB1-AS1' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.486 | Q11 | Are there any NAA30 SNPs that have a statistically significant adjusted SMR p-value in association with Alzheimer's Disease and what tissues are they significant in? | No, based on the Whole Brain and Whole Blood samples tested there are no SNPs within the gene NAA30 that are significantly associated with Alzheimer's Disease. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'NAA30' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.573 | Q11 | Are there any PCDH20 SNPs that have a statistically significant adjusted SMR p-value in association with Amyotrophic Lateral Sclerosis and what tissues are they significant in? | No, based on the Cerebellum, Whole Brain, Whole Blood and Prefrontal Cortex samples tested there are no SNPs within the gene PCDH20 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'PCDH20' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.74 | Q11 | Are there any BLMH SNPs that have a statistically significant adjusted SMR p-value in association with Lewy Body Dementia and what tissues are they significant in? | No, based on the Whole Brain, Whole Blood and Multi Ancestry Whole Brain samples tested there are no SNPs within the gene BLMH that are significantly associated with Lewy Body Dementia. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'LBD' AND Gene = 'BLMH' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.635 | Q11 | Are there any FAM215B SNPs that have a statistically significant adjusted SMR p-value in association with Alzheimer's Disease and what tissues are they significant in? | Yes, the FAM215B gene has 2 SNPs that are statistically significant in Alzheimer's Disease. Here are the SNPs along with their adjusted SMR p-values:
• rs2696466
• Prefrontal Cortex: Adjusted SMR multi-SNP P-value: 1.65e-07; HEIDI: 4.6279e-02
• rs55974014
• Cerebellum: Adjusted SMR multi-SNP P-value: 2.67e-06; HEIDI: 8.9359e-01
| SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'FAM215B' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1203022', 'Gene': 'FAM215B', 'topRSID': 'rs2696466', 'p_SMR_multi': 1.654759e-07, 'Omic_tissue': 'Prefrontal Cortex', 'p_HEIDI': 0.04627879}, {'UUID': 'NDD_SMR_genes_all_update_text_1690055', 'Gene': 'FAM215B', 'topRSID': 'rs55974014', 'p_SMR_multi': 2.668062e-06, 'Omic_tissue': 'Cerebellum', 'p_HEIDI': 0.8935862}] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.262 | Q11 | Are there any EI24 SNPs that have a statistically significant adjusted SMR p-value in association with Progressive supranuclear palsy and what tissues are they significant in? | No, based on the Whole Blood, Multi Ancestry Whole Brain and Whole Brain samples tested there are no SNPs within the gene EI24 that are significantly associated with Progressive supranuclear palsy. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'EI24' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.52 | Q11 | Are there any PTTG1 SNPs that have a statistically significant adjusted SMR p-value in association with Alzheimer's Disease and what tissues are they significant in? | No, based on the Cerebellum, Whole Brain, Whole Blood, Cortex, Skeletal Muscle and Multi Ancestry Whole Brain samples tested there are no SNPs within the gene PTTG1 that are significantly associated with Alzheimer's Disease. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'PTTG1' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.201 | Q11 | Are there any CEBPZ-AS1 SNPs that have a statistically significant adjusted SMR p-value in association with Parkinson's Disease and what tissues are they significant in? | No, based on the Whole Brain, Multi Ancestry Whole Brain and Whole Blood samples tested there are no SNPs within the gene CEBPZ-AS1 that are significantly associated with Parkinson's Disease. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'CEBPZ-AS1' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.432 | Q11 | Are there any KY SNPs that have a statistically significant adjusted SMR p-value in association with Progressive supranuclear palsy and what tissues are they significant in? | No, based on the Cerebellum, Cortex, Cerebellar Hemisphere and Whole Blood samples tested there are no SNPs within the gene KY that are significantly associated with Progressive supranuclear palsy. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'KY' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.1563 | Q11 | Are there any RND2 SNPs that have a statistically significant adjusted SMR p-value in association with Parkinson's Disease and what tissues are they significant in? | No, based on the Cerebellum, Whole Brain, Whole Blood, Tibial Nerve and Multi Ancestry Whole Brain samples tested there are no SNPs within the gene RND2 that are significantly associated with Parkinson's Disease. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'RND2' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.336 | Q11 | Are there any NSF SNPs that have a statistically significant adjusted SMR p-value in association with Parkinson's Disease and what tissues are they significant in? | Yes, the NSF gene has 2 SNPs that are statistically significant in Parkinson's Disease. Here are the SNPs along with their adjusted SMR p-values:
• rs62074125
• Whole Blood: Adjusted SMR multi-SNP P-value: 4.42e-10; HEIDI: 1.9028e-06
• rs3874943
• Prefrontal Cortex: Adjusted SMR multi-SNP P-value: 4.66e-08; HEIDI: 5.7680e-05
| SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'NSF' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1564795', 'Gene': 'NSF', 'topRSID': 'rs62074125', 'p_SMR_multi': 4.420217e-10, 'Omic_tissue': 'Whole Blood', 'p_HEIDI': 1.902752e-06}, {'UUID': 'NDD_SMR_genes_all_update_text_1242289', 'Gene': 'NSF', 'topRSID': 'rs3874943', 'p_SMR_multi': 4.658364e-08, 'Omic_tissue': 'Prefrontal Cortex', 'p_HEIDI': 5.767952e-05}] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.1557 | Q11 | Are there any PRR7 SNPs that have a statistically significant adjusted SMR p-value in association with Alzheimer's Disease and what tissues are they significant in? | No, based on the Whole Brain and Whole Blood samples tested there are no SNPs within the gene PRR7 that are significantly associated with Alzheimer's Disease. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'PRR7' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.1539 | Q11 | Are there any RDM1 SNPs that have a statistically significant adjusted SMR p-value in association with Alzheimer's Disease and what tissues are they significant in? | No, based on the Whole Brain, Whole Blood, Cortex and Prefrontal Cortex samples tested there are no SNPs within the gene RDM1 that are significantly associated with Alzheimer's Disease. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'RDM1' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.426 | Q11 | Are there any C12orf43 SNPs that have a statistically significant adjusted SMR p-value in association with Parkinson's Disease and what tissues are they significant in? | No, based on the Cerebellum, Whole Brain, Whole Blood, Cortex, Cerebellar Hemisphere, Prefrontal Cortex, Caudate Basal Ganglia, Tibial Nerve, Skeletal Muscle, Multi Ancestry Whole Brain, Anterior Cingulate Cortex BA24 and Nucleus Accumbens Basal samples tested there are no SNPs within the gene C12orf43 that are significantly associated with Parkinson's Disease. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'C12orf43' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.637 | Q11 | Are there any RP11-529H20.6 SNPs that have a statistically significant adjusted SMR p-value in association with Alzheimer's Disease and what tissues are they significant in? | No, based on the Prefrontal Cortex and Whole Blood samples tested there are no SNPs within the gene RP11-529H20.6 that are significantly associated with Alzheimer's Disease. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'RP11-529H20.6' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.941 | Q11 | Are there any C3orf54 SNPs that have a statistically significant adjusted SMR p-value in association with Lewy Body Dementia and what tissues are they significant in? | No, based on the Whole Blood samples tested there are no SNPs within the gene C3orf54 that are significantly associated with Lewy Body Dementia. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'LBD' AND Gene = 'C3orf54' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.993 | Q11 | Are there any CLPTM1L SNPs that have a statistically significant adjusted SMR p-value in association with Lewy Body Dementia and what tissues are they significant in? | No, based on the Whole Brain and Whole Blood samples tested there are no SNPs within the gene CLPTM1L that are significantly associated with Lewy Body Dementia. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'LBD' AND Gene = 'CLPTM1L' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.868 | Q11 | Are there any RELT SNPs that have a statistically significant adjusted SMR p-value in association with Frontotemporal Dementia and what tissues are they significant in? | No, based on the Whole Brain, Whole Blood, Cortex, Tibial Nerve, Skeletal Muscle and Multi Ancestry Whole Brain samples tested there are no SNPs within the gene RELT that are significantly associated with Frontotemporal Dementia. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'FTD' AND Gene = 'RELT' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.1951 | Q11 | Are there any CHRNA2 SNPs that have a statistically significant adjusted SMR p-value in association with Alzheimer's Disease and what tissues are they significant in? | Yes, the CHRNA2 gene has 1 SNP that is statistically significant in Alzheimer's Disease:
• rs2472554
• Cerebellum: Adjusted SMR multi-SNP P-value: 1.13e-07; HEIDI: 1.5797e-03 | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'CHRNA2' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_3683', 'Gene': 'CHRNA2', 'topRSID': 'rs2472554', 'p_SMR_multi': 1.132264e-07, 'Omic_tissue': 'Cerebellum', 'p_HEIDI': 0.001579673}] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.558 | Q11 | Are there any GRIN2C SNPs that have a statistically significant adjusted SMR p-value in association with Alzheimer's Disease and what tissues are they significant in? | No, based on the Whole Brain, Whole Blood, Cortex, Tibial Nerve and Multi Ancestry Whole Brain samples tested there are no SNPs within the gene GRIN2C that are significantly associated with Alzheimer's Disease. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'GRIN2C' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.433 | Q11 | Are there any AC009505.4 SNPs that have a statistically significant adjusted SMR p-value in association with Lewy Body Dementia and what tissues are they significant in? | No, based on the Whole Brain and Whole Blood samples tested there are no SNPs within the gene AC009505.4 that are significantly associated with Lewy Body Dementia. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'LBD' AND Gene = 'AC009505.4' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.1777 | Q11 | Are there any CPB2-AS1 SNPs that have a statistically significant adjusted SMR p-value in association with Progressive supranuclear palsy and what tissues are they significant in? | No, based on the Frontal Cortex, Cerebellar Hemisphere, Cortex, Caudate Basal Ganglia, Tibial Nerve, Hippocampus, Substantia nigra, Hypothalamus, Liver, Anterior Cingulate Cortex BA24, Putamen Basal Ganglia, Amygdala, Whole Brain, Cerebellum and Nucleus Accumbens Basal samples tested there are no SNPs within the gene CPB2-AS1 that are significantly associated with Progressive supranuclear palsy. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'CPB2-AS1' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.1834 | Q11 | Are there any RP11-196G11.4 SNPs that have a statistically significant adjusted SMR p-value in association with Parkinson's Disease and what tissues are they significant in? | Yes, the RP11-196G11.4 gene has 1 SNP that is statistically significant in Parkinson's Disease:
• rs4527034
• Whole Blood: Adjusted SMR multi-SNP P-value: 1.03e-06; HEIDI: 7.0901e-02 | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'RP11-196G11.4' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1563817', 'Gene': 'RP11-196G11.4', 'topRSID': 'rs4527034', 'p_SMR_multi': 1.034231e-06, 'Omic_tissue': 'Whole Blood', 'p_HEIDI': 0.07090143}] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.1977 | Q11 | Are there any GRIN3B SNPs that have a statistically significant adjusted SMR p-value in association with Alzheimer's Disease and what tissues are they significant in? | Yes, the GRIN3B gene has 3 SNPs that are statistically significant in Alzheimer's Disease. Here are the SNPs along with their adjusted SMR p-values:
• rs58342790
• Cortex: Adjusted SMR multi-SNP P-value: 2.31e-08; HEIDI: 3.2161e-06
• rs10401454
• Tibial Nerve: Adjusted SMR multi-SNP P-value: 4.16e-07; HEIDI: 1.4571e-04
• rs113337161
• Whole Blood: Adjusted SMR multi-SNP P-value: 1.68e-06; HEIDI: 3.1219e-06
| SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'GRIN3B' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1107629', 'Gene': 'GRIN3B', 'topRSID': 'rs58342790', 'p_SMR_multi': 2.312572e-08, 'Omic_tissue': 'Cortex', 'p_HEIDI': 3.21611e-06}, {'UUID': 'NDD_SMR_genes_all_update_text_1292157', 'Gene': 'GRIN3B', 'topRSID': 'rs10401454', 'p_SMR_multi': 4.157801e-07, 'Omic_tissue': 'Tibial Nerve', 'p_HEIDI': 0.0001457089}, {'UUID': 'NDD_SMR_genes_all_update_text_1503129', 'Gene': 'GRIN3B', 'topRSID': 'rs113337161', 'p_SMR_multi': 1.684956e-06, 'Omic_tissue': 'Whole Blood', 'p_HEIDI': 3.121865e-06}] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.1506 | Q11 | Are there any LRRC37A4P SNPs that have a statistically significant adjusted SMR p-value in association with Alzheimer's Disease and what tissues are they significant in? | Yes, the LRRC37A4P gene has 4 SNPs that are statistically significant in Alzheimer's Disease. Here are the SNPs along with their adjusted SMR p-values:
• rs112431991
• Whole Brain: Adjusted SMR multi-SNP P-value: 1.38e-07; HEIDI: 3.8022e-02
• rs62065450
• Multi Ancestry Whole Brain: Adjusted SMR multi-SNP P-value: 6.34e-07; HEIDI: 2.4679e-02
• rs2532276
• Prefrontal Cortex: Adjusted SMR multi-SNP P-value: 7.82e-07; HEIDI: 2.7052e-02
• rs1991556
• Cerebellum: Adjusted SMR multi-SNP P-value: 2.22e-06; HEIDI: 9.5106e-01
| SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'LRRC37A4P' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1610857', 'Gene': 'LRRC37A4P', 'topRSID': 'rs112431991', 'p_SMR_multi': 1.378159e-07, 'Omic_tissue': 'Whole Brain', 'p_HEIDI': 0.03802183}, {'UUID': 'NDD_SMR_genes_all_update_text_1396746', 'Gene': 'LRRC37A4P', 'topRSID': 'rs62065450', 'p_SMR_multi': 6.337944e-07, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'p_HEIDI': 0.02467926}, {'UUID': 'NDD_SMR_genes_all_update_text_1202998', 'Gene': 'LRRC37A4P', 'topRSID': 'rs2532276', 'p_SMR_multi': 7.822735e-07, 'Omic_tissue': 'Prefrontal Cortex', 'p_HEIDI': 0.02705218}, {'UUID': 'NDD_SMR_genes_all_update_text_1690038', 'Gene': 'LRRC37A4P', 'topRSID': 'rs1991556', 'p_SMR_multi': 2.216345e-06, 'Omic_tissue': 'Cerebellum', 'p_HEIDI': 0.9510566}] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.1622 | Q11 | Are there any PKP3 SNPs that have a statistically significant adjusted SMR p-value in association with Progressive supranuclear palsy and what tissues are they significant in? | No, based on the Cerebellum, Whole Brain, Whole Blood, Cortex, Tibial Nerve, Skeletal Muscle and Multi Ancestry Whole Brain samples tested there are no SNPs within the gene PKP3 that are significantly associated with Progressive supranuclear palsy. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'PKP3' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.404 | Q11 | Are there any KCNK7 SNPs that have a statistically significant adjusted SMR p-value in association with Alzheimer's Disease and what tissues are they significant in? | No, based on the Whole Brain, Whole Blood, Cortex and Multi Ancestry Whole Brain samples tested there are no SNPs within the gene KCNK7 that are significantly associated with Alzheimer's Disease. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'KCNK7' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.1791 | Q11 | Are there any FAM47E-STBD1 SNPs that have a statistically significant adjusted SMR p-value in association with Parkinson's Disease and what tissues are they significant in? | Yes, the FAM47E-STBD1 gene has 1 SNP that is statistically significant in Parkinson's Disease:
• rs56049812
• Whole Brain: Adjusted SMR multi-SNP P-value: 1.58e-06; HEIDI: 6.0158e-07 | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'FAM47E-STBD1' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_432141', 'Gene': 'FAM47E-STBD1', 'topRSID': 'rs56049812', 'p_SMR_multi': 1.584205e-06, 'Omic_tissue': 'Whole Brain', 'p_HEIDI': 6.015763e-07}] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.195 | Q11 | Are there any MREG SNPs that have a statistically significant adjusted SMR p-value in association with Alzheimer's Disease and what tissues are they significant in? | No, based on the Whole Brain, Whole Blood, Cortex, Prefrontal Cortex and Multi Ancestry Whole Brain samples tested there are no SNPs within the gene MREG that are significantly associated with Alzheimer's Disease. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'MREG' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.1281 | Q11 | Are there any KLC3 SNPs that have a statistically significant adjusted SMR p-value in association with Alzheimer's Disease and what tissues are they significant in? | Yes, the KLC3 gene has 1 SNP that is statistically significant in Alzheimer's Disease:
• rs9749618
• Whole Blood: Adjusted SMR multi-SNP P-value: 2.48e-06; HEIDI: 2.0080e-04 | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'KLC3' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1503919', 'Gene': 'KLC3', 'topRSID': 'rs9749618', 'p_SMR_multi': 2.478716e-06, 'Omic_tissue': 'Whole Blood', 'p_HEIDI': 0.0002007979}] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.1381 | Q11 | Are there any FBXL19 SNPs that have a statistically significant adjusted SMR p-value in association with Parkinson's Disease and what tissues are they significant in? | Yes, the FBXL19 gene has 1 SNP that is statistically significant in Parkinson's Disease:
• rs7200879
• Whole Blood: Adjusted SMR multi-SNP P-value: 2.68e-06; HEIDI: 7.5639e-02 | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'FBXL19' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_974661', 'Gene': 'FBXL19', 'topRSID': 'rs7200879', 'p_SMR_multi': 2.676196e-06, 'Omic_tissue': 'Whole Blood', 'p_HEIDI': 0.07563902}] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.677 | Q11 | Are there any CPSF3 SNPs that have a statistically significant adjusted SMR p-value in association with Alzheimer's Disease and what tissues are they significant in? | Yes, the CPSF3 gene has 1 SNP that is statistically significant in Alzheimer's Disease:
• rs7561588
• Whole Blood: Adjusted SMR multi-SNP P-value: 1.24e-06; HEIDI: 6.5355e-02 | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'CPSF3' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1491392', 'Gene': 'CPSF3', 'topRSID': 'rs7561588', 'p_SMR_multi': 1.236226e-06, 'Omic_tissue': 'Whole Blood', 'p_HEIDI': 0.06535516}] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.795 | Q11 | Are there any STX1B SNPs that have a statistically significant adjusted SMR p-value in association with Parkinson's Disease and what tissues are they significant in? | Yes, the STX1B gene has 5 SNPs that are statistically significant in Parkinson's Disease. Here are the SNPs along with their adjusted SMR p-values:
• rs9796794
• Whole Blood: Adjusted SMR multi-SNP P-value: 1.98e-07; HEIDI: 3.6011e-03
• rs58726213
• Tibial Nerve: Adjusted SMR multi-SNP P-value: 2.38e-07; HEIDI: 2.0596e-03
• rs13708
• Multi Ancestry Whole Brain: Adjusted SMR multi-SNP P-value: 4.40e-07; HEIDI: 7.6224e-07
• rs35961830
• Whole Blood: Adjusted SMR multi-SNP P-value: 1.40e-06; HEIDI: 9.6131e-03
• rs72800847
• Whole Blood: Adjusted SMR multi-SNP P-value: 1.51e-06; HEIDI: 3.0025e-02
| SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'STX1B' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_974667', 'Gene': 'STX1B', 'topRSID': 'rs9796794', 'p_SMR_multi': 1.979272e-07, 'Omic_tissue': 'Whole Blood', 'p_HEIDI': 0.003601113}, {'UUID': 'NDD_SMR_genes_all_update_text_1328405', 'Gene': 'STX1B', 'topRSID': 'rs58726213', 'p_SMR_multi': 2.384535e-07, 'Omic_tissue': 'Tibial Nerve', 'p_HEIDI': 0.002059639}, {'UUID': 'NDD_SMR_genes_all_update_text_1435343', 'Gene': 'STX1B', 'topRSID': 'rs13708', 'p_SMR_multi': 4.398435e-07, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'p_HEIDI': 7.622405e-07}, {'UUID': 'NDD_SMR_genes_all_update_text_974674', 'Gene': 'STX1B', 'topRSID': 'rs35961830', 'p_SMR_multi': 1.400111e-06, 'Omic_tissue': 'Whole Blood', 'p_HEIDI': 0.009613103}, {'UUID': 'NDD_SMR_genes_all_update_text_974671', 'Gene': 'STX1B', 'topRSID': 'rs72800847', 'p_SMR_multi': 1.509539e-06, 'Omic_tissue': 'Whole Blood', 'p_HEIDI': 0.03002522}] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.1463 | Q11 | Are there any RN7SL656P SNPs that have a statistically significant adjusted SMR p-value in association with Parkinson's Disease and what tissues are they significant in? | Yes, the RN7SL656P gene has 1 SNP that is statistically significant in Parkinson's Disease:
• rs2950694
• Prefrontal Cortex: Adjusted SMR multi-SNP P-value: 4.02e-10; HEIDI: 2.4462e-03 | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'RN7SL656P' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1242282', 'Gene': 'RN7SL656P', 'topRSID': 'rs2950694', 'p_SMR_multi': 4.017801e-10, 'Omic_tissue': 'Prefrontal Cortex', 'p_HEIDI': 0.002446177}] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.1457 | Q11 | Are there any VKORC1 SNPs that have a statistically significant adjusted SMR p-value in association with Parkinson's Disease and what tissues are they significant in? | Yes, the VKORC1 gene has 3 SNPs that are statistically significant in Parkinson's Disease. Here are the SNPs along with their adjusted SMR p-values:
• rs9923231
• Liver: Adjusted SMR multi-SNP P-value: 2.75e-08; HEIDI: 1.5184e-03
• rs2884737
• Multi Ancestry Whole Brain: Adjusted SMR multi-SNP P-value: 5.10e-07; HEIDI: 2.0564e-08
• Whole Blood: Adjusted SMR multi-SNP P-value: 2.03e-06; HEIDI: 1.2408e-02
• rs57434408
• Skeletal Muscle: Adjusted SMR multi-SNP P-value: 5.48e-07; HEIDI: 1.2806e-01
| SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'VKORC1' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1476296', 'Gene': 'VKORC1', 'topRSID': 'rs9923231', 'p_SMR_multi': 2.746395e-08, 'Omic_tissue': 'Liver', 'p_HEIDI': 0.001518397}, {'UUID': 'NDD_SMR_genes_all_update_text_1435347', 'Gene': 'VKORC1', 'topRSID': 'rs2884737', 'p_SMR_multi': 5.099183e-07, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'p_HEIDI': 2.056369e-08}, {'UUID': 'NDD_SMR_genes_all_update_text_1370182', 'Gene': 'VKORC1', 'topRSID': 'rs57434408', 'p_SMR_multi': 5.477439e-07, 'Omic_tissue': 'Skeletal Muscle', 'p_HEIDI': 0.1280606}, {'UUID': 'NDD_SMR_genes_all_update_text_1563815', 'Gene': 'VKORC1', 'topRSID': 'rs2884737', 'p_SMR_multi': 2.034428e-06, 'Omic_tissue': 'Whole Blood', 'p_HEIDI': 0.01240767}] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.144 | Q11 | Are there any RP11-386B13.4 SNPs that have a statistically significant adjusted SMR p-value in association with Amyotrophic Lateral Sclerosis and what tissues are they significant in? | No, based on the Whole Brain and Whole Blood samples tested there are no SNPs within the gene RP11-386B13.4 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'RP11-386B13.4' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.1188 | Q11 | Are there any ADSS SNPs that have a statistically significant adjusted SMR p-value in association with Amyotrophic Lateral Sclerosis and what tissues are they significant in? | No, based on the Whole Brain, Caudate Basal Ganglia, Tibial Nerve, Skeletal Muscle, Multi Ancestry Whole Brain and Whole Blood samples tested there are no SNPs within the gene ADSS that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'ADSS' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.3 | Q11 | Are there any AC023137.2 SNPs that have a statistically significant adjusted SMR p-value in association with Frontotemporal Dementia and what tissues are they significant in? | No, based on the Prefrontal Cortex samples tested there are no SNPs within the gene AC023137.2 that are significantly associated with Frontotemporal Dementia. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'FTD' AND Gene = 'AC023137.2' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.743 | Q11 | Are there any BCAM SNPs that have a statistically significant adjusted SMR p-value in association with Alzheimer's Disease and what tissues are they significant in? | Yes, the BCAM gene has 2 SNPs that are statistically significant in Alzheimer's Disease. Here are the SNPs along with their adjusted SMR p-values:
• rs7249750
• Whole Brain: Adjusted SMR multi-SNP P-value: 8.23e-07; HEIDI: 4.1871e-03
• rs28399647
• Multi Ancestry Whole Brain: Adjusted SMR multi-SNP P-value: 1.37e-06; HEIDI: 6.5505e-05
| SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'BCAM' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_122460', 'Gene': 'BCAM', 'topRSID': 'rs7249750', 'p_SMR_multi': 8.232666e-07, 'Omic_tissue': 'Whole Brain', 'p_HEIDI': 0.004187093}, {'UUID': 'NDD_SMR_genes_all_update_text_1397645', 'Gene': 'BCAM', 'topRSID': 'rs28399647', 'p_SMR_multi': 1.367791e-06, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'p_HEIDI': 6.550525e-05}] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.1871 | Q11 | Are there any RP11-164P12.4 SNPs that have a statistically significant adjusted SMR p-value in association with Amyotrophic Lateral Sclerosis and what tissues are they significant in? | No, based on the Whole Brain and Whole Blood samples tested there are no SNPs within the gene RP11-164P12.4 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'RP11-164P12.4' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.1516 | Q11 | Are there any CBLC SNPs that have a statistically significant adjusted SMR p-value in association with Alzheimer's Disease and what tissues are they significant in? | Yes, the CBLC gene has 1 SNP that is statistically significant in Alzheimer's Disease:
• rs2965118
• Whole Blood: Adjusted SMR multi-SNP P-value: 1.68e-08; HEIDI: 3.5269e-03 | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'CBLC' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_637417', 'Gene': 'CBLC', 'topRSID': 'rs2965118', 'p_SMR_multi': 1.680736e-08, 'Omic_tissue': 'Whole Blood', 'p_HEIDI': 0.003526909}] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.343 | Q11 | Are there any RP1-293L6.1 SNPs that have a statistically significant adjusted SMR p-value in association with Amyotrophic Lateral Sclerosis and what tissues are they significant in? | No, based on the Whole Blood, Frontal Cortex, Cerebellar Hemisphere, Prefrontal Cortex, Cortex, Caudate Basal Ganglia, Substantia nigra, Hypothalamus, Anterior Cingulate Cortex BA24, Putamen Basal Ganglia, Whole Brain, Cerebellum and Nucleus Accumbens Basal samples tested there are no SNPs within the gene RP1-293L6.1 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'RP1-293L6.1' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.626 | Q11 | Are there any CHRNE SNPs that have a statistically significant adjusted SMR p-value in association with Alzheimer's Disease and what tissues are they significant in? | Yes, the CHRNE gene has 4 SNPs that are statistically significant in Alzheimer's Disease. Here are the SNPs along with their adjusted SMR p-values:
• rs72835059
• Multi Ancestry Whole Brain: Adjusted SMR multi-SNP P-value: 2.58e-07; HEIDI: 5.8533e-03
• Whole Blood: Adjusted SMR multi-SNP P-value: 2.68e-07; HEIDI: 1.2962e-03
• Tibial Nerve: Adjusted SMR multi-SNP P-value: 2.26e-06; HEIDI: 3.4867e-03
• rs78767298
• Whole Blood: Adjusted SMR multi-SNP P-value: 6.80e-07; HEIDI: 1.3839e-02
• rs72835064
• Cortex: Adjusted SMR multi-SNP P-value: 7.87e-07; HEIDI: 6.4255e-03
• rs72835069
• Cortex: Adjusted SMR multi-SNP P-value: 2.70e-06; HEIDI: 4.3312e-02
| SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'CHRNE' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1396448', 'Gene': 'CHRNE', 'topRSID': 'rs72835059', 'p_SMR_multi': 2.576933e-07, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'p_HEIDI': 0.005853277}, {'UUID': 'NDD_SMR_genes_all_update_text_1501911', 'Gene': 'CHRNE', 'topRSID': 'rs72835059', 'p_SMR_multi': 2.678717e-07, 'Omic_tissue': 'Whole Blood', 'p_HEIDI': 0.001296214}, {'UUID': 'NDD_SMR_genes_all_update_text_589010', 'Gene': 'CHRNE', 'topRSID': 'rs78767298', 'p_SMR_multi': 6.797463e-07, 'Omic_tissue': 'Whole Blood', 'p_HEIDI': 0.01383914}, {'UUID': 'NDD_SMR_genes_all_update_text_1106579', 'Gene': 'CHRNE', 'topRSID': 'rs72835064', 'p_SMR_multi': 7.873601e-07, 'Omic_tissue': 'Cortex', 'p_HEIDI': 0.006425493}, {'UUID': 'NDD_SMR_genes_all_update_text_1291498', 'Gene': 'CHRNE', 'topRSID': 'rs72835059', 'p_SMR_multi': 2.261932e-06, 'Omic_tissue': 'Tibial Nerve', 'p_HEIDI': 0.003486666}, {'UUID': 'NDD_SMR_genes_all_update_text_1246971', 'Gene': 'CHRNE', 'topRSID': 'rs72835069', 'p_SMR_multi': 2.702617e-06, 'Omic_tissue': 'Cortex', 'p_HEIDI': 0.04331229}] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.484 | Q11 | Are there any KANSL1 SNPs that have a statistically significant adjusted SMR p-value in association with Parkinson's Disease and what tissues are they significant in? | Yes, the KANSL1 gene has 31 SNPs that are statistically significant in Parkinson's Disease. Here are the top 10 SNPs along with their adjusted SMR p-values:
• rs12150087
• Whole Brain: Adjusted SMR multi-SNP P-value: 8.11e-20; HEIDI: 9.0699e-03
• rs1966345
• Whole Brain: Adjusted SMR multi-SNP P-value: 2.28e-19; HEIDI: 6.5228e-02
• rs2732615
• Prefrontal Cortex: Adjusted SMR multi-SNP P-value: 1.93e-15; HEIDI: 1.6277e-04
• rs199447
• Multi Ancestry Whole Brain: Adjusted SMR multi-SNP P-value: 5.39e-15; HEIDI: 1.8003e-04
• rs169201
• Cortex: Adjusted SMR multi-SNP P-value: 8.23e-15; HEIDI: 1.5766e-06
• rs2532233
• Whole Blood: Adjusted SMR multi-SNP P-value: 1.02e-14; HEIDI: 2.9895e-05
• Whole Brain: Adjusted SMR multi-SNP P-value: 2.11e-11; HEIDI: 1.5985e-06
• rs571792649
• Whole Brain: Adjusted SMR multi-SNP P-value: 1.08e-13; HEIDI: -9.9990e+03
• rs17661015
• Whole Brain: Adjusted SMR multi-SNP P-value: 1.86e-11; HEIDI: 1.8741e-01
• rs62060852
• Whole Brain: Adjusted SMR multi-SNP P-value: 5.11e-11; HEIDI: 3.7325e-06
• rs12951057
• Whole Blood: Adjusted SMR multi-SNP P-value: 6.80e-11; HEIDI: 6.3608e-11
| SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'KANSL1' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_491139', 'Gene': 'KANSL1', 'topRSID': 'rs12150087', 'p_SMR_multi': 8.107128999999999e-20, 'Omic_tissue': 'Whole Brain', 'p_HEIDI': 0.009069932}, {'UUID': 'NDD_SMR_genes_all_update_text_491142', 'Gene': 'KANSL1', 'topRSID': 'rs1966345', 'p_SMR_multi': 2.276563e-19, 'Omic_tissue': 'Whole Brain', 'p_HEIDI': 0.06522781}, {'UUID': 'NDD_SMR_genes_all_update_text_491143', 'Gene': 'KANSL1', 'topRSID': 'rs1966345', 'p_SMR_multi': 4.679141e-19, 'Omic_tissue': 'Whole Brain', 'p_HEIDI': 0.09682033}, {'UUID': 'NDD_SMR_genes_all_update_text_1242276', 'Gene': 'KANSL1', 'topRSID': 'rs2732615', 'p_SMR_multi': 1.92913e-15, 'Omic_tissue': 'Prefrontal Cortex', 'p_HEIDI': 0.0001627713}, {'UUID': 'NDD_SMR_genes_all_update_text_491144', 'Gene': 'KANSL1', 'topRSID': 'rs1966345', 'p_SMR_multi': 2.370965e-15, 'Omic_tissue': 'Whole Brain', 'p_HEIDI': 0.2294804}, {'UUID': 'NDD_SMR_genes_all_update_text_491141', 'Gene': 'KANSL1', 'topRSID': 'rs1966345', 'p_SMR_multi': 3.504748e-15, 'Omic_tissue': 'Whole Brain', 'p_HEIDI': 0.06040555}, {'UUID': 'NDD_SMR_genes_all_update_text_1435917', 'Gene': 'KANSL1', 'topRSID': 'rs199447', 'p_SMR_multi': 5.393131e-15, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'p_HEIDI': 0.0001800316}, {'UUID': 'NDD_SMR_genes_all_update_text_1147256', 'Gene': 'KANSL1', 'topRSID': 'rs169201', 'p_SMR_multi': 8.230037e-15, 'Omic_tissue': 'Cortex', 'p_HEIDI': 1.576563e-06}, {'UUID': 'NDD_SMR_genes_all_update_text_948907', 'Gene': 'KANSL1', 'topRSID': 'rs2532233', 'p_SMR_multi': 1.024112e-14, 'Omic_tissue': 'Whole Blood', 'p_HEIDI': 2.989456e-05}, {'UUID': 'NDD_SMR_genes_all_update_text_491152', 'Gene': 'KANSL1', 'topRSID': 'rs571792649', 'p_SMR_multi': 1.08158e-13, 'Omic_tissue': 'Whole Brain', 'p_HEIDI': -9999.0}, {'UUID': 'NDD_SMR_genes_all_update_text_491140', 'Gene': 'KANSL1', 'topRSID': 'rs12150087', 'p_SMR_multi': 5.036561e-13, 'Omic_tissue': 'Whole Brain', 'p_HEIDI': 0.007535882}, {'UUID': 'NDD_SMR_genes_all_update_text_491138', 'Gene': 'KANSL1', 'topRSID': 'rs17661015', 'p_SMR_multi': 1.856985e-11, 'Omic_tissue': 'Whole Brain', 'p_HEIDI': 0.18741}, {'UUID': 'NDD_SMR_genes_all_update_text_1640221', 'Gene': 'KANSL1', 'topRSID': 'rs2532233', 'p_SMR_multi': 2.111139e-11, 'Omic_tissue': 'Whole Brain', 'p_HEIDI': 1.598528e-06}, {'UUID': 'NDD_SMR_genes_all_update_text_491136', 'Gene': 'KANSL1', 'topRSID': 'rs62060852', 'p_SMR_multi': 5.109934e-11, 'Omic_tissue': 'Whole Brain', 'p_HEIDI': 3.732509e-06}, {'UUID': 'NDD_SMR_genes_all_update_text_1564784', 'Gene': 'KANSL1', 'topRSID': 'rs12951057', 'p_SMR_multi': 6.804262e-11, 'Omic_tissue': 'Whole Blood', 'p_HEIDI': 6.360757e-11}, {'UUID': 'NDD_SMR_genes_all_update_text_491134', 'Gene': 'KANSL1', 'topRSID': 'rs8712', 'p_SMR_multi': 1.362111e-10, 'Omic_tissue': 'Whole Brain', 'p_HEIDI': 0.01710958}, {'UUID': 'NDD_SMR_genes_all_update_text_19647', 'Gene': 'KANSL1', 'topRSID': 'rs112995313', 'p_SMR_multi': 2.193847e-10, 'Omic_tissue': 'Cerebellum', 'p_HEIDI': 8.102405e-06}, {'UUID': 'NDD_SMR_genes_all_update_text_1370545', 'Gene': 'KANSL1', 'topRSID': 'rs2532345', 'p_SMR_multi': 3.631865e-10, 'Omic_tissue': 'Skeletal Muscle', 'p_HEIDI': 6.052526e-07}, {'UUID': 'NDD_SMR_genes_all_update_text_1679565', 'Gene': 'KANSL1', 'topRSID': 'rs2532345', 'p_SMR_multi': 1.445017e-09, 'Omic_tissue': 'Whole Blood', 'p_HEIDI': 3.439324e-07}, {'UUID': 'NDD_SMR_genes_all_update_text_948901', 'Gene': 'KANSL1', 'topRSID': 'rs199529', 'p_SMR_multi': 3.416427e-09, 'Omic_tissue': 'Whole Blood', 'p_HEIDI': 0.003856081}, {'UUID': 'NDD_SMR_genes_all_update_text_948911', 'Gene': 'KANSL1', 'topRSID': 'rs17692129', 'p_SMR_multi': 4.741722e-09, 'Omic_tissue': 'Whole Blood', 'p_HEIDI': 3.860039e-05}, {'UUID': 'NDD_SMR_genes_all_update_text_948903', 'Gene': 'KANSL1', 'topRSID': 'rs199525', 'p_SMR_multi': 1.584326e-08, 'Omic_tissue': 'Whole Blood', 'p_HEIDI': 5.032854e-06}, {'UUID': 'NDD_SMR_genes_all_update_text_491147', 'Gene': 'KANSL1', 'topRSID': 'rs2316955', 'p_SMR_multi': 2.081418e-08, 'Omic_tissue': 'Whole Brain', 'p_HEIDI': 8.753545e-09}, {'UUID': 'NDD_SMR_genes_all_update_text_948906', 'Gene': 'KANSL1', 'topRSID': 'rs2532233', 'p_SMR_multi': 2.335339e-08, 'Omic_tissue': 'Whole Blood', 'p_HEIDI': 0.0002406445}, {'UUID': 'NDD_SMR_genes_all_update_text_948900', 'Gene': 'KANSL1', 'topRSID': 'rs62074125', 'p_SMR_multi': 3.272916e-08, 'Omic_tissue': 'Whole Blood', 'p_HEIDI': 0.0002885019}, {'UUID': 'NDD_SMR_genes_all_update_text_491148', 'Gene': 'KANSL1', 'topRSID': 'rs545648705', 'p_SMR_multi': 4.17127e-08, 'Omic_tissue': 'Whole Brain', 'p_HEIDI': 0.7180818}, {'UUID': 'NDD_SMR_genes_all_update_text_948910', 'Gene': 'KANSL1', 'topRSID': 'rs62057144', 'p_SMR_multi': 6.236973e-08, 'Omic_tissue': 'Whole Blood', 'p_HEIDI': 0.09405019}, {'UUID': 'NDD_SMR_genes_all_update_text_491151', 'Gene': 'KANSL1', 'topRSID': 'rs2668665', 'p_SMR_multi': 6.875006e-08, 'Omic_tissue': 'Whole Brain', 'p_HEIDI': -9999.0}, {'UUID': 'NDD_SMR_genes_all_update_text_948904', 'Gene': 'KANSL1', 'topRSID': 'rs17692129', 'p_SMR_multi': 1.268598e-07, 'Omic_tissue': 'Whole Blood', 'p_HEIDI': 0.000163555}, {'UUID': 'NDD_SMR_genes_all_update_text_33014', 'Gene': 'KANSL1', 'topRSID': 'rs79730878', 'p_SMR_multi': 1.517388e-07, 'Omic_tissue': 'Hippocampus', 'p_HEIDI': 0.007037855}, {'UUID': 'NDD_SMR_genes_all_update_text_948914', 'Gene': 'KANSL1', 'topRSID': 'rs111273167', 'p_SMR_multi': 1.546877e-07, 'Omic_tissue': 'Whole Blood', 'p_HEIDI': 0.0004057759}, {'UUID': 'NDD_SMR_genes_all_update_text_948902', 'Gene': 'KANSL1', 'topRSID': 'rs112197756', 'p_SMR_multi': 1.845403e-07, 'Omic_tissue': 'Whole Blood', 'p_HEIDI': 0.0008704151}, {'UUID': 'NDD_SMR_genes_all_update_text_491135', 'Gene': 'KANSL1', 'topRSID': 'rs41374248', 'p_SMR_multi': 2.075434e-07, 'Omic_tissue': 'Whole Brain', 'p_HEIDI': 0.7473406}, {'UUID': 'NDD_SMR_genes_all_update_text_948905', 'Gene': 'KANSL1', 'topRSID': 'rs117913167', 'p_SMR_multi': 2.610539e-07, 'Omic_tissue': 'Whole Blood', 'p_HEIDI': 0.001894197}, {'UUID': 'NDD_SMR_genes_all_update_text_491150', 'Gene': 'KANSL1', 'topRSID': 'rs551913443', 'p_SMR_multi': 8.29812e-07, 'Omic_tissue': 'Whole Brain', 'p_HEIDI': 0.005142257}, {'UUID': 'NDD_SMR_genes_all_update_text_30028', 'Gene': 'KANSL1', 'topRSID': 'rs199451', 'p_SMR_multi': 1.277333e-06, 'Omic_tissue': 'Spinalcord', 'p_HEIDI': 0.01301229}, {'UUID': 'NDD_SMR_genes_all_update_text_948915', 'Gene': 'KANSL1', 'topRSID': 'rs35937770', 'p_SMR_multi': 1.34252e-06, 'Omic_tissue': 'Whole Blood', 'p_HEIDI': 0.001908699}, {'UUID': 'NDD_SMR_genes_all_update_text_491145', 'Gene': 'KANSL1', 'topRSID': 'rs2696610', 'p_SMR_multi': 2.040211e-06, 'Omic_tissue': 'Whole Brain', 'p_HEIDI': 0.6005164}, {'UUID': 'NDD_SMR_genes_all_update_text_27182', 'Gene': 'KANSL1', 'topRSID': 'rs6503453', 'p_SMR_multi': 2.349001e-06, 'Omic_tissue': 'Basal Ganglia', 'p_HEIDI': 0.0001370049}] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.532 | Q11 | Are there any PRSS50 SNPs that have a statistically significant adjusted SMR p-value in association with Lewy Body Dementia and what tissues are they significant in? | No, based on the Whole Brain and Whole Blood samples tested there are no SNPs within the gene PRSS50 that are significantly associated with Lewy Body Dementia. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'LBD' AND Gene = 'PRSS50' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.268 | Q11 | Are there any RP11-169E6.4 SNPs that have a statistically significant adjusted SMR p-value in association with Frontotemporal Dementia and what tissues are they significant in? | No, based on the Whole Blood samples tested there are no SNPs within the gene RP11-169E6.4 that are significantly associated with Frontotemporal Dementia. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'FTD' AND Gene = 'RP11-169E6.4' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.1390 | Q11 | Are there any EMBP1 SNPs that have a statistically significant adjusted SMR p-value in association with Amyotrophic Lateral Sclerosis and what tissues are they significant in? | No, based on the Cerebellar Hemisphere, Whole Blood and Cerebellum samples tested there are no SNPs within the gene EMBP1 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'EMBP1' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.681 | Q11 | Are there any FAM215B SNPs that have a statistically significant adjusted SMR p-value in association with Parkinson's Disease and what tissues are they significant in? | Yes, the FAM215B gene has 5 SNPs that are statistically significant in Parkinson's Disease. Here are the SNPs along with their adjusted SMR p-values:
• rs3874943
• Prefrontal Cortex: Adjusted SMR multi-SNP P-value: 4.32e-11; HEIDI: 2.6539e-08
• rs55974014
• Cerebellum: Adjusted SMR multi-SNP P-value: 1.45e-10; HEIDI: 1.3937e-02
• rs9896243
• Cerebellar Hemisphere: Adjusted SMR multi-SNP P-value: 8.12e-09; HEIDI: 6.1615e-02
• rs7218567
• Whole Brain: Adjusted SMR multi-SNP P-value: 2.53e-08; HEIDI: 4.3155e-03
• rs17698176
• Whole Blood: Adjusted SMR multi-SNP P-value: 3.15e-08; HEIDI: 2.8201e-09
• Tibial Nerve: Adjusted SMR multi-SNP P-value: 6.10e-08; HEIDI: 2.3994e-05
| SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'FAM215B' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1242287', 'Gene': 'FAM215B', 'topRSID': 'rs3874943', 'p_SMR_multi': 4.320919e-11, 'Omic_tissue': 'Prefrontal Cortex', 'p_HEIDI': 2.653919e-08}, {'UUID': 'NDD_SMR_genes_all_update_text_1710359', 'Gene': 'FAM215B', 'topRSID': 'rs55974014', 'p_SMR_multi': 1.449976e-10, 'Omic_tissue': 'Cerebellum', 'p_HEIDI': 0.01393696}, {'UUID': 'NDD_SMR_genes_all_update_text_1191181', 'Gene': 'FAM215B', 'topRSID': 'rs9896243', 'p_SMR_multi': 8.116734e-09, 'Omic_tissue': 'Cerebellar Hemisphere', 'p_HEIDI': 0.06161497}, {'UUID': 'NDD_SMR_genes_all_update_text_1640231', 'Gene': 'FAM215B', 'topRSID': 'rs7218567', 'p_SMR_multi': 2.52907e-08, 'Omic_tissue': 'Whole Brain', 'p_HEIDI': 0.00431549}, {'UUID': 'NDD_SMR_genes_all_update_text_1564794', 'Gene': 'FAM215B', 'topRSID': 'rs17698176', 'p_SMR_multi': 3.149567e-08, 'Omic_tissue': 'Whole Blood', 'p_HEIDI': 2.820072e-09}, {'UUID': 'NDD_SMR_genes_all_update_text_1328943', 'Gene': 'FAM215B', 'topRSID': 'rs17698176', 'p_SMR_multi': 6.104463e-08, 'Omic_tissue': 'Tibial Nerve', 'p_HEIDI': 2.399358e-05}] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.492 | Q11 | Are there any FAM209B SNPs that have a statistically significant adjusted SMR p-value in association with Alzheimer's Disease and what tissues are they significant in? | Yes, the FAM209B gene has 1 SNP that is statistically significant in Alzheimer's Disease:
• rs56104586
• Whole Blood: Adjusted SMR multi-SNP P-value: 5.44e-07; HEIDI: 1.0512e-04 | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'FAM209B' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1504675', 'Gene': 'FAM209B', 'topRSID': 'rs56104586', 'p_SMR_multi': 5.439246e-07, 'Omic_tissue': 'Whole Blood', 'p_HEIDI': 0.0001051177}] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.445 | Q11 | Are there any RAD51AP1 SNPs that have a statistically significant adjusted SMR p-value in association with Lewy Body Dementia and what tissues are they significant in? | No, based on the Whole Brain and Whole Blood samples tested there are no SNPs within the gene RAD51AP1 that are significantly associated with Lewy Body Dementia. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'LBD' AND Gene = 'RAD51AP1' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.274 | Q11 | Are there any NUP85 SNPs that have a statistically significant adjusted SMR p-value in association with Amyotrophic Lateral Sclerosis and what tissues are they significant in? | No, based on the Cerebellum, Basal Ganglia, Spinalcord, Whole Brain, Whole Blood, Cortex, Frontal Cortex, Cerebellar Hemisphere, Prefrontal Cortex, Caudate Basal Ganglia, Tibial Nerve, Skeletal Muscle, Hippocampus, Multi Ancestry Whole Brain, Substantia nigra, Hypothalamus, Liver, Anterior Cingulate Cortex BA24, Putamen Basal Ganglia, Amygdala and Nucleus Accumbens Basal samples tested there are no SNPs within the gene NUP85 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'NUP85' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.187 | Q11 | Are there any PIWIL3 SNPs that have a statistically significant adjusted SMR p-value in association with Progressive supranuclear palsy and what tissues are they significant in? | No, based on the Whole Brain and Whole Blood samples tested there are no SNPs within the gene PIWIL3 that are significantly associated with Progressive supranuclear palsy. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'PIWIL3' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.950 | Q11 | Are there any FGFRL1 SNPs that have a statistically significant adjusted SMR p-value in association with Parkinson's Disease and what tissues are they significant in? | Yes, the FGFRL1 gene has 2 SNPs that are statistically significant in Parkinson's Disease. Here are the SNPs along with their adjusted SMR p-values:
• rs74921869
• Whole Blood: Adjusted SMR multi-SNP P-value: 1.86e-07; HEIDI: 1.4964e-05
• rs6812278
• Whole Blood: Adjusted SMR multi-SNP P-value: 6.32e-07; HEIDI: 1.5741e-03
| SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'FGFRL1' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_996326', 'Gene': 'FGFRL1', 'topRSID': 'rs74921869', 'p_SMR_multi': 1.862031e-07, 'Omic_tissue': 'Whole Blood', 'p_HEIDI': 1.496361e-05}, {'UUID': 'NDD_SMR_genes_all_update_text_996328', 'Gene': 'FGFRL1', 'topRSID': 'rs6812278', 'p_SMR_multi': 6.316275e-07, 'Omic_tissue': 'Whole Blood', 'p_HEIDI': 0.001574098}] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.247 | Q11 | Are there any RFFL SNPs that have a statistically significant adjusted SMR p-value in association with Amyotrophic Lateral Sclerosis and what tissues are they significant in? | No, based on the Cortex, Prefrontal Cortex, Tibial Nerve, Skeletal Muscle, Multi Ancestry Whole Brain, Whole Blood, Whole Brain and Nucleus Accumbens Basal samples tested there are no SNPs within the gene RFFL that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'RFFL' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.1100 | Q11 | Are there any RBPMS2 SNPs that have a statistically significant adjusted SMR p-value in association with Frontotemporal Dementia and what tissues are they significant in? | No, based on the Whole Brain, Whole Blood, Cortex, Frontal Cortex, Prefrontal Cortex, Multi Ancestry Whole Brain and Anterior Cingulate Cortex BA24 samples tested there are no SNPs within the gene RBPMS2 that are significantly associated with Frontotemporal Dementia. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'FTD' AND Gene = 'RBPMS2' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.1018 | Q11 | Are there any CPLX1 SNPs that have a statistically significant adjusted SMR p-value in association with Progressive supranuclear palsy and what tissues are they significant in? | No, based on the Whole Brain, Whole Blood, Tibial Nerve, Skeletal Muscle and Multi Ancestry Whole Brain samples tested there are no SNPs within the gene CPLX1 that are significantly associated with Progressive supranuclear palsy. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'CPLX1' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.590 | Q11 | Are there any MIR3939 SNPs that have a statistically significant adjusted SMR p-value in association with Alzheimer's Disease and what tissues are they significant in? | No, based on the Whole Brain and Whole Blood samples tested there are no SNPs within the gene MIR3939 that are significantly associated with Alzheimer's Disease. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'MIR3939' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.1629 | Q11 | Are there any CASS4 SNPs that have a statistically significant adjusted SMR p-value in association with Alzheimer's Disease and what tissues are they significant in? | Yes, the CASS4 gene has 2 SNPs that are statistically significant in Alzheimer's Disease. Here are the SNPs along with their adjusted SMR p-values:
• rs6014722
• Whole Blood: Adjusted SMR multi-SNP P-value: 9.72e-09; HEIDI: 3.0445e-02
• rs718022
• Prefrontal Cortex: Adjusted SMR multi-SNP P-value: 7.21e-07; HEIDI: 6.7046e-03
| SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'CASS4' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1504670', 'Gene': 'CASS4', 'topRSID': 'rs6014722', 'p_SMR_multi': 9.717309e-09, 'Omic_tissue': 'Whole Blood', 'p_HEIDI': 0.03044452}, {'UUID': 'NDD_SMR_genes_all_update_text_1653496', 'Gene': 'CASS4', 'topRSID': 'rs6014722', 'p_SMR_multi': 2.493025e-07, 'Omic_tissue': 'Whole Blood', 'p_HEIDI': 0.2014311}, {'UUID': 'NDD_SMR_genes_all_update_text_1204217', 'Gene': 'CASS4', 'topRSID': 'rs718022', 'p_SMR_multi': 7.206564e-07, 'Omic_tissue': 'Prefrontal Cortex', 'p_HEIDI': 0.00670464}] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.535 | Q11 | Are there any CR1 SNPs that have a statistically significant adjusted SMR p-value in association with Parkinson's Disease and what tissues are they significant in? | No, based on the Cerebellum, Basal Ganglia, Whole Brain, Whole Blood, Cortex, Prefrontal Cortex, Caudate Basal Ganglia and Multi Ancestry Whole Brain samples tested there are no SNPs within the gene CR1 that are significantly associated with Parkinson's Disease. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'CR1' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.899 | Q11 | Are there any CTB-161M19.2 SNPs that have a statistically significant adjusted SMR p-value in association with Parkinson's Disease and what tissues are they significant in? | No, based on the Prefrontal Cortex samples tested there are no SNPs within the gene CTB-161M19.2 that are significantly associated with Parkinson's Disease. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'CTB-161M19.2' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.1483 | Q11 | Are there any TRMT5 SNPs that have a statistically significant adjusted SMR p-value in association with Alzheimer's Disease and what tissues are they significant in? | No, based on the Multi Ancestry Whole Brain and Whole Blood samples tested there are no SNPs within the gene TRMT5 that are significantly associated with Alzheimer's Disease. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'TRMT5' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.1109 | Q11 | Are there any GPX4 SNPs that have a statistically significant adjusted SMR p-value in association with Alzheimer's Disease and what tissues are they significant in? | Yes, the GPX4 gene has 1 SNP that is statistically significant in Alzheimer's Disease:
• rs8103188
• Whole Blood: Adjusted SMR multi-SNP P-value: 6.03e-13; HEIDI: 1.9815e-04 | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'GPX4' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1503135', 'Gene': 'GPX4', 'topRSID': 'rs8103188', 'p_SMR_multi': 6.033717e-13, 'Omic_tissue': 'Whole Blood', 'p_HEIDI': 0.0001981533}] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.421 | Q11 | Are there any AC093627.10 SNPs that have a statistically significant adjusted SMR p-value in association with Parkinson's Disease and what tissues are they significant in? | No, based on the Whole Brain, Whole Blood, Frontal Cortex, Cerebellar Hemisphere, Prefrontal Cortex, Cortex, Caudate Basal Ganglia, Tibial Nerve, Skeletal Muscle, Hippocampus, Multi Ancestry Whole Brain, Hypothalamus, Anterior Cingulate Cortex BA24, Cerebellum and Nucleus Accumbens Basal samples tested there are no SNPs within the gene AC093627.10 that are significantly associated with Parkinson's Disease. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'AC093627.10' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.277 | Q11 | Are there any RP11-71H17.9 SNPs that have a statistically significant adjusted SMR p-value in association with Frontotemporal Dementia and what tissues are they significant in? | No, based on the Prefrontal Cortex and Whole Brain samples tested there are no SNPs within the gene RP11-71H17.9 that are significantly associated with Frontotemporal Dementia. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'FTD' AND Gene = 'RP11-71H17.9' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.1174 | Q11 | Are there any CR1 SNPs that have a statistically significant adjusted SMR p-value in association with Alzheimer's Disease and what tissues are they significant in? | Yes, the CR1 gene has 4 SNPs that are statistically significant in Alzheimer's Disease. Here are the SNPs along with their adjusted SMR p-values:
• rs679515
• Multi Ancestry Whole Brain: Adjusted SMR multi-SNP P-value: 2.09e-15; HEIDI: 9.0925e-08
• Prefrontal Cortex: Adjusted SMR multi-SNP P-value: 1.08e-12; HEIDI: 2.8394e-03
• Whole Brain: Adjusted SMR multi-SNP P-value: 2.10e-12; HEIDI: 2.5685e-01
• Cortex: Adjusted SMR multi-SNP P-value: 4.46e-08; HEIDI: 9.5634e-01
• rs1830763
• Cortex: Adjusted SMR multi-SNP P-value: 3.83e-15; HEIDI: 6.0285e-02
• Cerebellum: Adjusted SMR multi-SNP P-value: 1.72e-08; HEIDI: 1.0919e-01
• rs6697005
• Basal Ganglia: Adjusted SMR multi-SNP P-value: 2.48e-08; HEIDI: 7.8615e-02
• rs2093760
• Caudate Basal Ganglia: Adjusted SMR multi-SNP P-value: 3.25e-08; HEIDI: 5.3293e-01
| SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'CR1' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1389608', 'Gene': 'CR1', 'topRSID': 'rs679515', 'p_SMR_multi': 2.085436e-15, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'p_HEIDI': 9.09245e-08}, {'UUID': 'NDD_SMR_genes_all_update_text_1105231', 'Gene': 'CR1', 'topRSID': 'rs1830763', 'p_SMR_multi': 3.826448e-15, 'Omic_tissue': 'Cortex', 'p_HEIDI': 0.06028479}, {'UUID': 'NDD_SMR_genes_all_update_text_1195476', 'Gene': 'CR1', 'topRSID': 'rs679515', 'p_SMR_multi': 1.077391e-12, 'Omic_tissue': 'Prefrontal Cortex', 'p_HEIDI': 0.002839407}, {'UUID': 'NDD_SMR_genes_all_update_text_1605472', 'Gene': 'CR1', 'topRSID': 'rs679515', 'p_SMR_multi': 2.099284e-12, 'Omic_tissue': 'Whole Brain', 'p_HEIDI': 0.2568474}, {'UUID': 'NDD_SMR_genes_all_update_text_2441', 'Gene': 'CR1', 'topRSID': 'rs1830763', 'p_SMR_multi': 1.723238e-08, 'Omic_tissue': 'Cerebellum', 'p_HEIDI': 0.1091882}, {'UUID': 'NDD_SMR_genes_all_update_text_24520', 'Gene': 'CR1', 'topRSID': 'rs6697005', 'p_SMR_multi': 2.479933e-08, 'Omic_tissue': 'Basal Ganglia', 'p_HEIDI': 0.07861539}, {'UUID': 'NDD_SMR_genes_all_update_text_1265685', 'Gene': 'CR1', 'topRSID': 'rs2093760', 'p_SMR_multi': 3.250883e-08, 'Omic_tissue': 'Caudate Basal Ganglia', 'p_HEIDI': 0.5329306}, {'UUID': 'NDD_SMR_genes_all_update_text_1244290', 'Gene': 'CR1', 'topRSID': 'rs679515', 'p_SMR_multi': 4.463872e-08, 'Omic_tissue': 'Cortex', 'p_HEIDI': 0.9563398}] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.1487 | Q11 | Are there any AC005281.2 SNPs that have a statistically significant adjusted SMR p-value in association with Alzheimer's Disease and what tissues are they significant in? | No, based on the Whole Brain and Whole Blood samples tested there are no SNPs within the gene AC005281.2 that are significantly associated with Alzheimer's Disease. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'AC005281.2' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.1456 | Q11 | Are there any DND1P1 SNPs that have a statistically significant adjusted SMR p-value in association with Alzheimer's Disease and what tissues are they significant in? | Yes, the DND1P1 gene has 3 SNPs that are statistically significant in Alzheimer's Disease. Here are the SNPs along with their adjusted SMR p-values:
• rs451737
• Whole Brain: Adjusted SMR multi-SNP P-value: 1.11e-06; HEIDI: 9.4314e-01
• rs55974014
• Whole Blood: Adjusted SMR multi-SNP P-value: 1.32e-06; HEIDI: -9.9990e+03
• Tibial Nerve: Adjusted SMR multi-SNP P-value: 1.59e-06; HEIDI: -9.9990e+03
• Skeletal Muscle: Adjusted SMR multi-SNP P-value: 1.92e-06; HEIDI: -9.9990e+03
• rs199447
• Whole Blood: Adjusted SMR multi-SNP P-value: 1.52e-06; HEIDI: 1.0162e-01
| SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'DND1P1' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_115145', 'Gene': 'DND1P1', 'topRSID': 'rs451737', 'p_SMR_multi': 1.11147e-06, 'Omic_tissue': 'Whole Brain', 'p_HEIDI': 0.9431384}, {'UUID': 'NDD_SMR_genes_all_update_text_1652495', 'Gene': 'DND1P1', 'topRSID': 'rs55974014', 'p_SMR_multi': 1.320859e-06, 'Omic_tissue': 'Whole Blood', 'p_HEIDI': -9999.0}, {'UUID': 'NDD_SMR_genes_all_update_text_591167', 'Gene': 'DND1P1', 'topRSID': 'rs199447', 'p_SMR_multi': 1.52052e-06, 'Omic_tissue': 'Whole Blood', 'p_HEIDI': 0.1016157}, {'UUID': 'NDD_SMR_genes_all_update_text_1291754', 'Gene': 'DND1P1', 'topRSID': 'rs55974014', 'p_SMR_multi': 1.593695e-06, 'Omic_tissue': 'Tibial Nerve', 'p_HEIDI': -9999.0}, {'UUID': 'NDD_SMR_genes_all_update_text_1343149', 'Gene': 'DND1P1', 'topRSID': 'rs55974014', 'p_SMR_multi': 1.91696e-06, 'Omic_tissue': 'Skeletal Muscle', 'p_HEIDI': -9999.0}] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.253 | Q11 | Are there any RP11-180C16.1 SNPs that have a statistically significant adjusted SMR p-value in association with Lewy Body Dementia and what tissues are they significant in? | No, based on the Prefrontal Cortex samples tested there are no SNPs within the gene RP11-180C16.1 that are significantly associated with Lewy Body Dementia. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'LBD' AND Gene = 'RP11-180C16.1' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.419 | Q11 | Are there any CTD-2020K17.4 SNPs that have a statistically significant adjusted SMR p-value in association with Alzheimer's Disease and what tissues are they significant in? | No, based on the Whole Brain, Whole Blood, Cerebellar Hemisphere, Prefrontal Cortex and Liver samples tested there are no SNPs within the gene CTD-2020K17.4 that are significantly associated with Alzheimer's Disease. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'CTD-2020K17.4' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.1590 | Q11 | Are there any RP11-114H24.5 SNPs that have a statistically significant adjusted SMR p-value in association with Frontotemporal Dementia and what tissues are they significant in? | No, based on the Tibial Nerve samples tested there are no SNPs within the gene RP11-114H24.5 that are significantly associated with Frontotemporal Dementia. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'FTD' AND Gene = 'RP11-114H24.5' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.1895 | Q11 | Are there any MMP15 SNPs that have a statistically significant adjusted SMR p-value in association with Parkinson's Disease and what tissues are they significant in? | No, based on the Whole Brain and Whole Blood samples tested there are no SNPs within the gene MMP15 that are significantly associated with Parkinson's Disease. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'MMP15' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.582 | Q11 | Are there any RP1-122P22.2 SNPs that have a statistically significant adjusted SMR p-value in association with Alzheimer's Disease and what tissues are they significant in? | No, based on the Whole Brain, Whole Blood and Skeletal Muscle samples tested there are no SNPs within the gene RP1-122P22.2 that are significantly associated with Alzheimer's Disease. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'RP1-122P22.2' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.314 | Q11 | Are there any BTBD7 SNPs that have a statistically significant adjusted SMR p-value in association with Frontotemporal Dementia and what tissues are they significant in? | No, based on the Whole Brain, Whole Blood, Prefrontal Cortex and Multi Ancestry Whole Brain samples tested there are no SNPs within the gene BTBD7 that are significantly associated with Frontotemporal Dementia. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'FTD' AND Gene = 'BTBD7' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.1962 | Q11 | Are there any FMNL1 SNPs that have a statistically significant adjusted SMR p-value in association with Parkinson's Disease and what tissues are they significant in? | Yes, the FMNL1 gene has 3 SNPs that are statistically significant in Parkinson's Disease. Here are the SNPs along with their adjusted SMR p-values:
• rs62063276
• Multi Ancestry Whole Brain: Adjusted SMR multi-SNP P-value: 1.99e-11; HEIDI: -9.9990e+03
• Cerebellum: Adjusted SMR multi-SNP P-value: 1.14e-10; HEIDI: -9.9990e+03
• rs12150464
• Cerebellum: Adjusted SMR multi-SNP P-value: 2.16e-10; HEIDI: -9.9990e+03
• rs62062283
• Cerebellar Hemisphere: Adjusted SMR multi-SNP P-value: 8.61e-10; HEIDI: -9.9990e+03
| SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'FMNL1' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1435910', 'Gene': 'FMNL1', 'topRSID': 'rs62063276', 'p_SMR_multi': 1.990946e-11, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'p_HEIDI': -9999.0}, {'UUID': 'NDD_SMR_genes_all_update_text_1710337', 'Gene': 'FMNL1', 'topRSID': 'rs62063276', 'p_SMR_multi': 1.14186e-10, 'Omic_tissue': 'Cerebellum', 'p_HEIDI': -9999.0}, {'UUID': 'NDD_SMR_genes_all_update_text_19643', 'Gene': 'FMNL1', 'topRSID': 'rs12150464', 'p_SMR_multi': 2.164011e-10, 'Omic_tissue': 'Cerebellum', 'p_HEIDI': -9999.0}, {'UUID': 'NDD_SMR_genes_all_update_text_1191159', 'Gene': 'FMNL1', 'topRSID': 'rs62062283', 'p_SMR_multi': 8.610321e-10, 'Omic_tissue': 'Cerebellar Hemisphere', 'p_HEIDI': -9999.0}] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.387 | Q11 | Are there any ARHGAP12 SNPs that have a statistically significant adjusted SMR p-value in association with Alzheimer's Disease and what tissues are they significant in? | No, based on the Whole Brain, Whole Blood, Cortex, Prefrontal Cortex, Tibial Nerve and Multi Ancestry Whole Brain samples tested there are no SNPs within the gene ARHGAP12 that are significantly associated with Alzheimer's Disease. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'ARHGAP12' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.541 | Q11 | Are there any C11orf85 SNPs that have a statistically significant adjusted SMR p-value in association with Alzheimer's Disease and what tissues are they significant in? | No, based on the Whole Brain and Whole Blood samples tested there are no SNPs within the gene C11orf85 that are significantly associated with Alzheimer's Disease. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'C11orf85' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.431 | Q11 | Are there any ACMSD SNPs that have a statistically significant adjusted SMR p-value in association with Parkinson's Disease and what tissues are they significant in? | Yes, the ACMSD gene has 1 SNP that is statistically significant in Parkinson's Disease:
• rs4953936
• Whole Blood: Adjusted SMR multi-SNP P-value: 2.78e-06; HEIDI: 9.9891e-02 | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'ACMSD' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1019156', 'Gene': 'ACMSD', 'topRSID': 'rs4953936', 'p_SMR_multi': 2.77516e-06, 'Omic_tissue': 'Whole Blood', 'p_HEIDI': 0.09989063}] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.657 | Q11 | Are there any MT2A SNPs that have a statistically significant adjusted SMR p-value in association with Parkinson's Disease and what tissues are they significant in? | No, based on the Whole Brain, Whole Blood and Cortex samples tested there are no SNPs within the gene MT2A that are significantly associated with Parkinson's Disease. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'MT2A' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.1642 | Q11 | Are there any PRR22 SNPs that have a statistically significant adjusted SMR p-value in association with Progressive supranuclear palsy and what tissues are they significant in? | No, based on the Whole Brain, Multi Ancestry Whole Brain and Whole Blood samples tested there are no SNPs within the gene PRR22 that are significantly associated with Progressive supranuclear palsy. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'PRR22' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.1318 | Q11 | Are there any PILRA SNPs that have a statistically significant adjusted SMR p-value in association with Frontotemporal Dementia and what tissues are they significant in? | No, based on the Cerebellum, Basal Ganglia, Hippocampus, Whole Brain, Cortex, Frontal Cortex, Cerebellar Hemisphere, Prefrontal Cortex, Caudate Basal Ganglia, Tibial Nerve, Skeletal Muscle, Multi Ancestry Whole Brain, Substantia nigra, Hypothalamus, Liver, Anterior Cingulate Cortex BA24, Whole Blood, Putamen Basal Ganglia, Amygdala and Nucleus Accumbens Basal samples tested there are no SNPs within the gene PILRA that are significantly associated with Frontotemporal Dementia. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'FTD' AND Gene = 'PILRA' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.1358 | Q11 | Are there any SRCAP SNPs that have a statistically significant adjusted SMR p-value in association with Parkinson's Disease and what tissues are they significant in? | Yes, the SRCAP gene has 1 SNP that is statistically significant in Parkinson's Disease:
• rs3747481
• Whole Blood: Adjusted SMR multi-SNP P-value: 1.15e-06; HEIDI: 2.5088e-02 | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'SRCAP' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_974653', 'Gene': 'SRCAP', 'topRSID': 'rs3747481', 'p_SMR_multi': 1.154869e-06, 'Omic_tissue': 'Whole Blood', 'p_HEIDI': 0.02508775}] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.414 | Q11 | Are there any MAMDC4 SNPs that have a statistically significant adjusted SMR p-value in association with Parkinson's Disease and what tissues are they significant in? | No, based on the Whole Blood samples tested there are no SNPs within the gene MAMDC4 that are significantly associated with Parkinson's Disease. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'MAMDC4' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.1615 | Q11 | Are there any IQCD SNPs that have a statistically significant adjusted SMR p-value in association with Frontotemporal Dementia and what tissues are they significant in? | No, based on the Whole Blood, Cortex and Multi Ancestry Whole Brain samples tested there are no SNPs within the gene IQCD that are significantly associated with Frontotemporal Dementia. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'FTD' AND Gene = 'IQCD' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.687 | Q11 | Are there any AC012442.6 SNPs that have a statistically significant adjusted SMR p-value in association with Lewy Body Dementia and what tissues are they significant in? | No, based on the Whole Blood samples tested there are no SNPs within the gene AC012442.6 that are significantly associated with Lewy Body Dementia. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'LBD' AND Gene = 'AC012442.6' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.621 | Q11 | Are there any RNASEH1-AS1 SNPs that have a statistically significant adjusted SMR p-value in association with Frontotemporal Dementia and what tissues are they significant in? | No, based on the Multi Ancestry Whole Brain and Whole Blood samples tested there are no SNPs within the gene RNASEH1-AS1 that are significantly associated with Frontotemporal Dementia. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'FTD' AND Gene = 'RNASEH1-AS1' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.923 | Q11 | Are there any SLC4A2 SNPs that have a statistically significant adjusted SMR p-value in association with Alzheimer's Disease and what tissues are they significant in? | No, based on the Whole Brain, Whole Blood and Cerebellar Hemisphere samples tested there are no SNPs within the gene SLC4A2 that are significantly associated with Alzheimer's Disease. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'SLC4A2' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.1199 | Q11 | Are there any GNGT2 SNPs that have a statistically significant adjusted SMR p-value in association with Alzheimer's Disease and what tissues are they significant in? | Yes, the GNGT2 gene has 1 SNP that is statistically significant in Alzheimer's Disease:
• rs4794029
• Whole Blood: Adjusted SMR multi-SNP P-value: 7.74e-07; HEIDI: 5.8511e-06 | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'GNGT2' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1502503', 'Gene': 'GNGT2', 'topRSID': 'rs4794029', 'p_SMR_multi': 7.742807e-07, 'Omic_tissue': 'Whole Blood', 'p_HEIDI': 5.851104e-06}] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.839 | Q11 | Are there any RP11-366M4.11 SNPs that have a statistically significant adjusted SMR p-value in association with Parkinson's Disease and what tissues are they significant in? | No, based on the Prefrontal Cortex, Caudate Basal Ganglia, Tibial Nerve, Whole Blood and Nucleus Accumbens Basal samples tested there are no SNPs within the gene RP11-366M4.11 that are significantly associated with Parkinson's Disease. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'RP11-366M4.11' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.1771 | Q11 | Are there any SLC6A5 SNPs that have a statistically significant adjusted SMR p-value in association with Alzheimer's Disease and what tissues are they significant in? | No, based on the Whole Brain, Whole Blood and Cortex samples tested there are no SNPs within the gene SLC6A5 that are significantly associated with Alzheimer's Disease. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'SLC6A5' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.953 | Q11 | Are there any LILRA3 SNPs that have a statistically significant adjusted SMR p-value in association with Alzheimer's Disease and what tissues are they significant in? | Yes, the LILRA3 gene has 1 SNP that is statistically significant in Alzheimer's Disease:
• rs367070
• Whole Blood: Adjusted SMR multi-SNP P-value: 1.33e-06; HEIDI: 3.0232e-04 | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'LILRA3' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1504180', 'Gene': 'LILRA3', 'topRSID': 'rs367070', 'p_SMR_multi': 1.334091e-06, 'Omic_tissue': 'Whole Blood', 'p_HEIDI': 0.0003023186}] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.185 | Q11 | Are there any RGS2 SNPs that have a statistically significant adjusted SMR p-value in association with Amyotrophic Lateral Sclerosis and what tissues are they significant in? | No, based on the Whole Brain, Whole Blood and Tibial Nerve samples tested there are no SNPs within the gene RGS2 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'RGS2' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.1072 | Q11 | Are there any DFFB SNPs that have a statistically significant adjusted SMR p-value in association with Lewy Body Dementia and what tissues are they significant in? | No, based on the Cerebellum, Whole Brain, Whole Blood, Cortex, Frontal Cortex, Cerebellar Hemisphere, Prefrontal Cortex, Caudate Basal Ganglia, Tibial Nerve, Skeletal Muscle, Hippocampus, Multi Ancestry Whole Brain, Hypothalamus, Liver, Anterior Cingulate Cortex BA24, Putamen Basal Ganglia and Nucleus Accumbens Basal samples tested there are no SNPs within the gene DFFB that are significantly associated with Lewy Body Dementia. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'LBD' AND Gene = 'DFFB' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.711 | Q11 | Are there any DYNLRB2 SNPs that have a statistically significant adjusted SMR p-value in association with Lewy Body Dementia and what tissues are they significant in? | No, based on the Whole Brain samples tested there are no SNPs within the gene DYNLRB2 that are significantly associated with Lewy Body Dementia. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'LBD' AND Gene = 'DYNLRB2' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.173 | Q11 | Are there any C20orf194 SNPs that have a statistically significant adjusted SMR p-value in association with Progressive supranuclear palsy and what tissues are they significant in? | No, based on the Hippocampus, Whole Brain, Whole Blood, Cortex, Tibial Nerve, Skeletal Muscle, Multi Ancestry Whole Brain, Putamen Basal Ganglia and Nucleus Accumbens Basal samples tested there are no SNPs within the gene C20orf194 that are significantly associated with Progressive supranuclear palsy. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'C20orf194' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
Q11.296 | Q11 | Are there any ZNF222 SNPs that have a statistically significant adjusted SMR p-value in association with Amyotrophic Lateral Sclerosis and what tissues are they significant in? | No, based on the Whole Brain samples tested there are no SNPs within the gene ZNF222 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT UUID, Gene, topRSID, p_SMR_multi, Omic_tissue, p_HEIDI
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'ZNF222' AND p_SMR_multi < 2.95e-6
ORDER BY p_SMR_multi
LIMIT 100 | [] | refined | Select, Order By, Multi-Filter, Threshold | SMR Significance |
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