uuid stringlengths 4 8 | template_uuid stringclasses 40
values | question stringlengths 13 193 | answer stringlengths 29 2.2k | benchmark_query stringlengths 133 622 | execution_results stringlengths 2 1.14M | query_type stringclasses 2
values | sql_category stringclasses 26
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Q59.701 | Q59 | What is the genetic target of the small molecule drug Abt-288, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Abt-288 is HRH3. Abt-288 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%abt-288%" OR LOWER(tradeNames_string) LIKE "%abt-288%" OR LOWER(drug... | [{'UUID': 'DrugGeneTargets_v2_1247', 'drugName': 'Abt-288', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH3 (ENSG00000101180)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.61 | Q59 | What is the genetic target of the small molecule drug Tafamidis Meglumine, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Tafamidis Meglumine is TTR. Tafamidis Meglumine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tafamidis meglumine%" OR LOWER(tradeNames_string) LIKE "%tafamidis m... | [{'UUID': 'DrugGeneTargets_v2_8', 'drugName': 'Tafamidis Meglumine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TTR (ENSG00000118271)', 'yearOfFirstApproval': 2019, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.843 | Q59 | What is the genetic target of the antibody drug Domagrozumab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Domagrozumab is MSTN. Domagrozumab reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%domagrozumab%" OR LOWER(tradeNames_string) LIKE "%domagrozumab%" OR ... | [{'UUID': 'DrugGeneTargets_v2_5421', 'drugName': 'Domagrozumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'MSTN (ENSG00000138379)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1356 | Q59 | What is the genetic target of the protein drug Serelaxin, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the protein drug Serelaxin: RXFP1 and RXFP2. Serelaxin reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%serelaxin%" OR LOWER(tradeNames_string) LIKE "%serelaxin%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_3540', 'drugName': 'Serelaxin', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'RXFP1 (ENSG00000171509), RXFP2 (ENSG00000133105)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_3541', 'drugName': 'Serelaxin', 'drugM... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.76 | Q59 | What is the genetic target of the small molecule drug Dipivefrin, and what is its status in clinical trials and FDA approval? | There are 9 genetic targets of the small molecule drug Dipivefrin: ADRA1A, ADRA2A, ADRB1, ADRB2, ADRA2C, ADRA1D, ADRA1B, ADRA2B, and ADRB3. Dipivefrin reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%dipivefrin%" OR LOWER(tradeNames_string) LIKE "%dipivefrin%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_842', 'drugName': 'Dipivefrin', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRA1A (ENSG00000120907), ADRA2A (ENSG00000150594), ADRB1 (ENSG00000043591), ADRB2 (ENSG00000169252), ADRA2C (ENSG00000184160), ADRA1D (ENSG00000171873), ADRA1B (ENSG00000170214), ADRA2B (ENS... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.165 | Q59 | What is the genetic target of the antibody drug A33 131I, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug A33 131I is GPA33. A33 131I reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%a33 131i%" OR LOWER(tradeNames_string) LIKE "%a33 131i%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_2310', 'drugName': 'A33 131I', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'GPA33 (ENSG00000143167)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.576 | Q59 | What is the genetic target of the small molecule drug Apazone, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Apazone: PTGS2 and PTGS1. Apazone reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%apazone%" OR LOWER(tradeNames_string) LIKE "%apazone%" OR LOWER(drug... | [{'UUID': 'DrugGeneTargets_v2_3917', 'drugName': 'Apazone', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGS2 (ENSG00000073756), PTGS1 (ENSG00000095303)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.959 | Q59 | What is the genetic target of the small molecule drug Raltitrexed, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Raltitrexed is TYMS. Raltitrexed reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%raltitrexed%" OR LOWER(tradeNames_string) LIKE "%raltitrexed%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_721', 'drugName': 'Raltitrexed', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TYMS (ENSG00000176890)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1540 | Q59 | What is the genetic target of the small molecule drug Loperamide Hydrochloride, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Loperamide Hydrochloride is OPRM1. Loperamide Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%loperamide hydrochloride%" OR LOWER(tradeNames_string) LIKE "%lopera... | [{'UUID': 'DrugGeneTargets_v2_6052', 'drugName': 'Loperamide Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'OPRM1 (ENSG00000112038)', 'yearOfFirstApproval': 1976, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1046 | Q59 | What is the genetic target of the small molecule drug Apalutamide, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Apalutamide is AR. Apalutamide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%apalutamide%" OR LOWER(tradeNames_string) LIKE "%apalutamide%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_6164', 'drugName': 'Apalutamide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'AR (ENSG00000169083)', 'yearOfFirstApproval': 2018, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1706 | Q59 | What is the genetic target of the small molecule drug Benzydamine Hydrochloride, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Benzydamine Hydrochloride: PTGS2 and PTGS1. Benzydamine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%benzydamine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%benzy... | [{'UUID': 'DrugGeneTargets_v2_3576', 'drugName': 'Benzydamine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGS2 (ENSG00000073756), PTGS1 (ENSG00000095303)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.513 | Q59 | What is the genetic target of the small molecule drug Saxagliptin, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Saxagliptin is DPP4. Saxagliptin reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%saxagliptin%" OR LOWER(tradeNames_string) LIKE "%saxagliptin%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_6010', 'drugName': 'Saxagliptin', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DPP4 (ENSG00000197635)', 'yearOfFirstApproval': 2009, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2239', 'drugName': 'Saxagliptin Hydrochloride', 'drug... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.46 | Q59 | What is the genetic target of the small molecule drug Methscopolamine Bromide, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Methscopolamine Bromide: CHRM1 and CHRM3. Methscopolamine Bromide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%methscopolamine bromide%" OR LOWER(tradeNames_string) LIKE "%methsco... | [{'UUID': 'DrugGeneTargets_v2_2695', 'drugName': 'Methscopolamine Bromide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRM1 (ENSG00000168539), CHRM3 (ENSG00000133019)', 'yearOfFirstApproval': 1953, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2696', 'drugNam... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.946 | Q59 | What is the genetic target of the protein drug Scy 635, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Scy 635 is PPIA. Scy 635 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%scy 635%" OR LOWER(tradeNames_string) LIKE "%scy 635%" OR LOWER(drug... | [{'UUID': 'DrugGeneTargets_v2_5084', 'drugName': 'Scy 635', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'PPIA (ENSG00000196262)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.366 | Q59 | What is the genetic target of the small molecule drug Sunitinib, and what is its status in clinical trials and FDA approval? | There are 9 genetic targets of the small molecule drug Sunitinib: RET, FLT1, FLT4, KDR, CSF1R, FLT3, KIT, PDGFRB, and PDGFRA. Sunitinib reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%sunitinib%" OR LOWER(tradeNames_string) LIKE "%sunitinib%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_3923', 'drugName': 'Sunitinib Malate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PDGFRB (ENSG00000113721), PDGFRA (ENSG00000134853), RET (ENSG00000165731), FLT1 (ENSG00000102755), FLT4 (ENSG00000037280), KDR (ENSG00000128052), CSF1R (ENSG00000182578), FLT3 (ENSG000... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.540 | Q59 | What is the genetic target of the small molecule drug Olumacostat Glasaretil, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Olumacostat Glasaretil: ACACA and ACACB. Olumacostat Glasaretil reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%olumacostat glasaretil%" OR LOWER(tradeNames_string) LIKE "%olumacos... | [{'UUID': 'DrugGeneTargets_v2_1425', 'drugName': 'Olumacostat Glasaretil', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ACACA (ENSG00000278540), ACACB (ENSG00000076555)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.79 | Q59 | What is the genetic target of the small molecule drug Mercaptopurine, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Mercaptopurine is PPAT. Mercaptopurine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%mercaptopurine%" OR LOWER(tradeNames_string) LIKE "%mercaptopurine%"... | [{'UUID': 'DrugGeneTargets_v2_2137', 'drugName': 'Mercaptopurine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PPAT (ENSG00000128059)', 'yearOfFirstApproval': 1953, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_5406', 'drugName': 'Mercaptopurine', 'drugMolecula... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1917 | Q59 | What is the genetic target of the small molecule drug Pramipexole Dihydrochloride, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Pramipexole Dihydrochloride: DRD2, DRD3, and DRD4. Pramipexole Dihydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%pramipexole dihydrochloride%" OR LOWER(tradeNames_string) LIKE "%pra... | [{'UUID': 'DrugGeneTargets_v2_5763', 'drugName': 'Pramipexole Dihydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DRD2 (ENSG00000149295), DRD3 (ENSG00000151577), DRD4 (ENSG00000069696)', 'yearOfFirstApproval': 1997, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1416 | Q59 | What is the genetic target of the small molecule drug Tropisetron, and what is its status in clinical trials and FDA approval? | There are 5 genetic targets of the small molecule drug Tropisetron: HTR3A, HTR3E, HTR3B, HTR3D, and HTR3C. Tropisetron reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tropisetron%" OR LOWER(tradeNames_string) LIKE "%tropisetron%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_3083', 'drugName': 'Tropisetron', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR3A (ENSG00000166736), HTR3E (ENSG00000186038), HTR3B (ENSG00000149305), HTR3D (ENSG00000186090), HTR3C (ENSG00000178084)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsAp... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.586 | Q59 | What is the genetic target of the small molecule drug Lacidipine, and what is its status in clinical trials and FDA approval? | There are 4 genetic targets of the small molecule drug Lacidipine: CACNA1C, CACNA1S, CACNA1D, and CACNA1F. Lacidipine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%lacidipine%" OR LOWER(tradeNames_string) LIKE "%lacidipine%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_575', 'drugName': 'Lacidipine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CACNA1C (ENSG00000151067), CACNA1S (ENSG00000081248), CACNA1D (ENSG00000157388), CACNA1F (ENSG00000102001)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1795 | Q59 | What is the genetic target of the small molecule drug Verdiperstat, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Verdiperstat is MPO. Verdiperstat reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%verdiperstat%" OR LOWER(tradeNames_string) LIKE "%verdiperstat%" OR ... | [{'UUID': 'DrugGeneTargets_v2_1006', 'drugName': 'Verdiperstat', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'MPO (ENSG00000005381)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.771 | Q59 | What is the genetic target of the small molecule drug Levocabastine, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Levocabastine is HRH1. Levocabastine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%levocabastine%" OR LOWER(tradeNames_string) LIKE "%levocabastine%" O... | [{'UUID': 'DrugGeneTargets_v2_396', 'drugName': 'Levocabastine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH1 (ENSG00000196639)', 'yearOfFirstApproval': 1993, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_674', 'drugName': 'Levocabastine Hydrochloride', 'dr... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.371 | Q59 | What is the genetic target of the small molecule drug Tecalcet Hydrochloride, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Tecalcet Hydrochloride is CASR. Tecalcet Hydrochloride reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tecalcet hydrochloride%" OR LOWER(tradeNames_string) LIKE "%tecalcet... | [{'UUID': 'DrugGeneTargets_v2_622', 'drugName': 'Tecalcet Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CASR (ENSG00000036828)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.809 | Q59 | What is the genetic target of the small molecule drug Cisapride, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Cisapride is HTR4. Cisapride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%cisapride%" OR LOWER(tradeNames_string) LIKE "%cisapride%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_3176', 'drugName': 'Cisapride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR4 (ENSG00000164270)', 'yearOfFirstApproval': 1993, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.31 | Q59 | What is the genetic target of the small molecule drug Rimegepant Sulfate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Rimegepant Sulfate is CALCRL. Rimegepant Sulfate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%rimegepant sulfate%" OR LOWER(tradeNames_string) LIKE "%rimegepant s... | [{'UUID': 'DrugGeneTargets_v2_3190', 'drugName': 'Rimegepant Sulfate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CALCRL (ENSG00000064989)', 'yearOfFirstApproval': 2020, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1960 | Q59 | What is the genetic target of the small molecule drug Segesterone Acetate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Segesterone Acetate is PGR. Segesterone Acetate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%segesterone acetate%" OR LOWER(tradeNames_string) LIKE "%segesterone... | [{'UUID': 'DrugGeneTargets_v2_692', 'drugName': 'Segesterone Acetate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PGR (ENSG00000082175)', 'yearOfFirstApproval': 2018, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1742 | Q59 | What is the genetic target of the small molecule drug Asciminib, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Asciminib: ABL1 and BCR. Asciminib reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%asciminib%" OR LOWER(tradeNames_string) LIKE "%asciminib%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_3412', 'drugName': 'Asciminib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ABL1 (ENSG00000097007), BCR (ENSG00000186716)', 'yearOfFirstApproval': 2021, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3413', 'drugName': 'Asciminib', ... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1577 | Q59 | What is the genetic target of the antibody drug Medi-578, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Medi-578 is NGF. Medi-578 reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%medi-578%" OR LOWER(tradeNames_string) LIKE "%medi-578%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_3953', 'drugName': 'Medi-578', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'NGF (ENSG00000134259)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.794 | Q59 | What is the genetic target of the small molecule drug Eflornithine, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Eflornithine is ODC1. Eflornithine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%eflornithine%" OR LOWER(tradeNames_string) LIKE "%eflornithine%" OR ... | [{'UUID': 'DrugGeneTargets_v2_1880', 'drugName': 'Eflornithine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ODC1 (ENSG00000115758)', 'yearOfFirstApproval': 1990, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_6018', 'drugName': 'Eflornithine', 'dr... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1249 | Q59 | What is the genetic target of the small molecule drug Tafamidis, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Tafamidis is TTR. Tafamidis reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tafamidis%" OR LOWER(tradeNames_string) LIKE "%tafamidis%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_8', 'drugName': 'Tafamidis Meglumine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TTR (ENSG00000118271)', 'yearOfFirstApproval': 2019, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3770', 'drugName': 'Tafamidis', 'drugMolecularTyp... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.501 | Q59 | What is the genetic target of the small molecule drug Camizestrant, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Camizestrant is ESR1. Camizestrant reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%camizestrant%" OR LOWER(tradeNames_string) LIKE "%camizestrant%" OR ... | [{'UUID': 'DrugGeneTargets_v2_1982', 'drugName': 'Camizestrant', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ESR1 (ENSG00000091831)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1551 | Q59 | What is the genetic target of the protein drug Lanreotide Acetate, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the protein drug Lanreotide Acetate: SSTR5 and SSTR2. Lanreotide Acetate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%lanreotide acetate%" OR LOWER(tradeNames_string) LIKE "%lanreotide a... | [{'UUID': 'DrugGeneTargets_v2_2626', 'drugName': 'Lanreotide Acetate', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'SSTR5 (ENSG00000162009), SSTR2 (ENSG00000180616)', 'yearOfFirstApproval': 2007, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2627', 'drugName': 'Lanreot... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1568 | Q59 | What is the genetic target of the small molecule drug Disopyramide, and what is its status in clinical trials and FDA approval? | There are 10 genetic targets of the small molecule drug Disopyramide: SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. Disopyramide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%disopyramide%" OR LOWER(tradeNames_string) LIKE "%disopyramide%" OR ... | [{'UUID': 'DrugGeneTargets_v2_2879', 'drugName': 'Disopyramide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SCN1A (ENSG00000144285), SCN5A (ENSG00000183873), SCN4A (ENSG00000007314), SCN7A (ENSG00000136546), SCN2A (ENSG00000136531), SCN9A (ENSG00000169432), SCN3A (ENSG00000153253), SCN11A (ENSG0... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.991 | Q59 | What is the genetic target of the small molecule drug Loxapine Hydrochloride, and what is its status in clinical trials and FDA approval? | There are 5 genetic targets of the small molecule drug Loxapine Hydrochloride: HTR2A, HTR2C, DRD2, DRD3, and DRD4. Loxapine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%loxapine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%loxapine... | [{'UUID': 'DrugGeneTargets_v2_5988', 'drugName': 'Loxapine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR2A (ENSG00000102468), HTR2C (ENSG00000147246), DRD2 (ENSG00000149295), DRD3 (ENSG00000151577), DRD4 (ENSG00000069696)', 'yearOfFirstApproval': 1976, 'maxClinicalTrialPhase': 4... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1574 | Q59 | What is the genetic target of the small molecule drug Dydrogesterone, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Dydrogesterone is PGR. Dydrogesterone reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%dydrogesterone%" OR LOWER(tradeNames_string) LIKE "%dydrogesterone%"... | [{'UUID': 'DrugGeneTargets_v2_4940', 'drugName': 'Dydrogesterone', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PGR (ENSG00000082175)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.45 | Q59 | What is the genetic target of the small molecule drug Amg-319, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Amg-319 is PIK3CD. Amg-319 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%amg-319%" OR LOWER(tradeNames_string) LIKE "%amg-319%" OR LOWER(drug... | [{'UUID': 'DrugGeneTargets_v2_4652', 'drugName': 'Amg-319', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PIK3CD (ENSG00000171608)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1608 | Q59 | What is the genetic target of the small molecule drug As-602868, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug As-602868: IKBKB and FLT3. As-602868 reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%as-602868%" OR LOWER(tradeNames_string) LIKE "%as-602868%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_1504', 'drugName': 'As-602868', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'IKBKB (ENSG00000104365), FLT3 (ENSG00000122025)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_1505', 'drugName': 'As-602868', ... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.171 | Q59 | What is the genetic target of the small molecule drug Chlorphenoxamine, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Chlorphenoxamine is HRH1. Chlorphenoxamine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%chlorphenoxamine%" OR LOWER(tradeNames_string) LIKE "%chlorphenoxami... | [{'UUID': 'DrugGeneTargets_v2_6059', 'drugName': 'Chlorphenoxamine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH1 (ENSG00000196639)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.307 | Q59 | What is the genetic target of the protein drug Argipressin Tannate, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the protein drug Argipressin Tannate: AVPR2, AVPR1A, and AVPR1B. Argipressin Tannate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%argipressin tannate%" OR LOWER(tradeNames_string) LIKE "%argipressin... | [{'UUID': 'DrugGeneTargets_v2_5273', 'drugName': 'Argipressin Tannate', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'AVPR2 (ENSG00000126895), AVPR1A (ENSG00000166148), AVPR1B (ENSG00000198049)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1957 | Q59 | What is the genetic target of the antibody drug Muromonab-Cd3, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the antibody drug Muromonab-Cd3: CD3E, CD3G, and CD3D. Muromonab-Cd3 reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%muromonab-cd3%" OR LOWER(tradeNames_string) LIKE "%muromonab-cd3%" O... | [{'UUID': 'DrugGeneTargets_v2_3214', 'drugName': 'Muromonab-Cd3', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'CD3E (ENSG00000198851), CD3G (ENSG00000160654), CD3D (ENSG00000167286)', 'yearOfFirstApproval': 1986, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1105 | Q59 | What is the genetic target of the small molecule drug Rocuronium, and what is its status in clinical trials and FDA approval? | There are 5 genetic targets of the small molecule drug Rocuronium: CHRNA1, CHRNG, CHRNB1, CHRND, and CHRNE. Rocuronium reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%rocuronium%" OR LOWER(tradeNames_string) LIKE "%rocuronium%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_1958', 'drugName': 'Rocuronium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRNA1 (ENSG00000138435), CHRNG (ENSG00000196811), CHRNB1 (ENSG00000170175), CHRND (ENSG00000135902), CHRNE (ENSG00000108556)', 'yearOfFirstApproval': 1994, 'maxClinicalTrialPhase': 4, 'drug... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1925 | Q59 | What is the genetic target of the small molecule drug Clomipramine Hydrochloride, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Clomipramine Hydrochloride is SLC6A4. Clomipramine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%clomipramine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%clom... | [{'UUID': 'DrugGeneTargets_v2_1137', 'drugName': 'Clomipramine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A4 (ENSG00000108576)', 'yearOfFirstApproval': 1989, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1038 | Q59 | What is the genetic target of the protein drug Insulin Aspart Protamine Recombinant, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Insulin Aspart Protamine Recombinant is INSR. Insulin Aspart Protamine Recombinant reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%insulin aspart protamine recombinant%" OR LOWER(tradeNames_string) L... | [{'UUID': 'DrugGeneTargets_v2_1048', 'drugName': 'Insulin Aspart Protamine Recombinant', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'INSR (ENSG00000171105)', 'yearOfFirstApproval': 2001, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.658 | Q59 | What is the genetic target of the protein drug Lerodalcibep, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Lerodalcibep is PCSK9. Lerodalcibep reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%lerodalcibep%" OR LOWER(tradeNames_string) LIKE "%lerodalcibep%" OR ... | [{'UUID': 'DrugGeneTargets_v2_6016', 'drugName': 'Lerodalcibep', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'PCSK9 (ENSG00000169174)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.373 | Q59 | What is the genetic target of the small molecule drug Amlodipine, and what is its status in clinical trials and FDA approval? | There are 4 genetic targets of the small molecule drug Amlodipine: CACNA1C, CACNA1S, CACNA1D, and CACNA1F. Amlodipine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%amlodipine%" OR LOWER(tradeNames_string) LIKE "%amlodipine%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_6132', 'drugName': 'Levamlodipine Maleate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CACNA1C (ENSG00000151067), CACNA1S (ENSG00000081248), CACNA1D (ENSG00000157388), CACNA1F (ENSG00000102001)', 'yearOfFirstApproval': 2019, 'maxClinicalTrialPhase': 4, 'drugIsApprov... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1661 | Q59 | What is the genetic target of the small molecule drug Bay-1082439, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Bay-1082439: PIK3CA and PIK3CB. Bay-1082439 reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%bay-1082439%" OR LOWER(tradeNames_string) LIKE "%bay-1082439%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_5191', 'drugName': 'Bay-1082439', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PIK3CA (ENSG00000121879), PIK3CB (ENSG00000051382)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_5192', 'drugName': 'Bay-108... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1513 | Q59 | What is the genetic target of the protein drug Protirelin, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Protirelin is TRHR. Protirelin reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%protirelin%" OR LOWER(tradeNames_string) LIKE "%protirelin%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_4776', 'drugName': 'Protirelin', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'TRHR (ENSG00000174417)', 'yearOfFirstApproval': 1976, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.778 | Q59 | What is the genetic target of the small molecule drug Racecadotril, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Racecadotril is MME. Racecadotril reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%racecadotril%" OR LOWER(tradeNames_string) LIKE "%racecadotril%" OR ... | [{'UUID': 'DrugGeneTargets_v2_5090', 'drugName': 'Racecadotril', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'MME (ENSG00000196549)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.328 | Q59 | What is the genetic target of the small molecule drug Probenecid, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Probenecid: SLC22A8, SLC22A6, and SLC22A11. Probenecid reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%probenecid%" OR LOWER(tradeNames_string) LIKE "%probenecid%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_1876', 'drugName': 'Probenecid', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC22A8 (ENSG00000149452), SLC22A6 (ENSG00000197901), SLC22A11 (ENSG00000168065)', 'yearOfFirstApproval': 1951, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1988 | Q59 | What is the genetic target of the small molecule drug Tamsulosin, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Tamsulosin: ADRA1A, ADRA1D, and ADRA1B. Tamsulosin reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tamsulosin%" OR LOWER(tradeNames_string) LIKE "%tamsulosin%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_1013', 'drugName': 'Tamsulosin', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRA1A (ENSG00000120907), ADRA1D (ENSG00000171873), ADRA1B (ENSG00000170214)', 'yearOfFirstApproval': 1997, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1924 | Q59 | What is the genetic target of the small molecule drug Ethacrynate Sodium, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Ethacrynate Sodium is SLC12A1. Ethacrynate Sodium reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ethacrynate sodium%" OR LOWER(tradeNames_string) LIKE "%ethacrynate ... | [{'UUID': 'DrugGeneTargets_v2_3044', 'drugName': 'Ethacrynate Sodium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC12A1 (ENSG00000074803)', 'yearOfFirstApproval': 1967, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.931 | Q59 | What is the genetic target of the small molecule drug Metoprolol Tartrate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Metoprolol Tartrate is ADRB1. Metoprolol Tartrate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%metoprolol tartrate%" OR LOWER(tradeNames_string) LIKE "%metoprolol ... | [{'UUID': 'DrugGeneTargets_v2_1301', 'drugName': 'Metoprolol Tartrate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRB1 (ENSG00000043591)', 'yearOfFirstApproval': 1978, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.188 | Q59 | What is the genetic target of the small molecule drug Sufugolix, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Sufugolix is GNRHR. Sufugolix reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%sufugolix%" OR LOWER(tradeNames_string) LIKE "%sufugolix%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_4059', 'drugName': 'Sufugolix', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'GNRHR (ENSG00000109163)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1595 | Q59 | What is the genetic target of the small molecule drug R-343, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug R-343 is SYK. R-343 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%r-343%" OR LOWER(tradeNames_string) LIKE "%r-343%" OR LOWER(drugSyno... | [{'UUID': 'DrugGeneTargets_v2_5761', 'drugName': 'R-343', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SYK (ENSG00000165025)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_21', 'drugName': 'R-343', 'drugMolecularType': 'Small molecule... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.772 | Q59 | What is the genetic target of the small molecule drug Codeine Phosphate, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Codeine Phosphate: OPRK1, OPRD1, and OPRM1. Codeine Phosphate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%codeine phosphate%" OR LOWER(tradeNames_string) LIKE "%codeine phosp... | [{'UUID': 'DrugGeneTargets_v2_4198', 'drugName': 'Dihydrocodeine Bitartrate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'OPRM1 (ENSG00000112038)', 'yearOfFirstApproval': 1983, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1990', 'drugName': 'Codeine Phosphate'... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1203 | Q59 | What is the genetic target of the small molecule drug Metoprolol Fumarate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Metoprolol Fumarate is ADRB1. Metoprolol Fumarate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%metoprolol fumarate%" OR LOWER(tradeNames_string) LIKE "%metoprolol ... | [{'UUID': 'DrugGeneTargets_v2_3227', 'drugName': 'Metoprolol Fumarate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRB1 (ENSG00000043591)', 'yearOfFirstApproval': 1989, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.500 | Q59 | What is the genetic target of the small molecule drug Ondansetron, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Ondansetron is HTR3A. Ondansetron reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ondansetron%" OR LOWER(tradeNames_string) LIKE "%ondansetron%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_4955', 'drugName': 'Ondansetron Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR3A (ENSG00000166736)', 'yearOfFirstApproval': 1991, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4695', 'drugName': 'Ondansetron', 'dru... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1064 | Q59 | What is the genetic target of the small molecule drug Pitolisant, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Pitolisant is HRH3. Pitolisant reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%pitolisant%" OR LOWER(tradeNames_string) LIKE "%pitolisant%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_1748', 'drugName': 'Pitolisant', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH3 (ENSG00000101180)', 'yearOfFirstApproval': 2019, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1676', 'drugName': 'Pitolisant Hydrochloride', 'drugMo... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1111 | Q59 | What is the genetic target of the protein drug Nafarelin Acetate, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Nafarelin Acetate is GNRHR. Nafarelin Acetate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%nafarelin acetate%" OR LOWER(tradeNames_string) LIKE "%nafarelin ace... | [{'UUID': 'DrugGeneTargets_v2_669', 'drugName': 'Nafarelin Acetate', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'GNRHR (ENSG00000109163)', 'yearOfFirstApproval': 1990, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.536 | Q59 | What is the genetic target of the small molecule drug Uproleselan, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Uproleselan is SELE. Uproleselan reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%uproleselan%" OR LOWER(tradeNames_string) LIKE "%uproleselan%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_2418', 'drugName': 'Uproleselan', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SELE (ENSG00000007908)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1601 | Q59 | What is the genetic target of the small molecule drug Spirapril Hydrochloride, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Spirapril Hydrochloride is ACE. Spirapril Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%spirapril hydrochloride%" OR LOWER(tradeNames_string) LIKE "%spirapr... | [{'UUID': 'DrugGeneTargets_v2_4466', 'drugName': 'Spirapril Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ACE (ENSG00000159640)', 'yearOfFirstApproval': 1994, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.752 | Q59 | What is the genetic target of the small molecule drug Phentolamine, and what is its status in clinical trials and FDA approval? | There are 6 genetic targets of the small molecule drug Phentolamine: ADRA1A, ADRA2A, ADRA2C, ADRA1D, ADRA1B, and ADRA2B. Phentolamine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%phentolamine%" OR LOWER(tradeNames_string) LIKE "%phentolamine%" OR ... | [{'UUID': 'DrugGeneTargets_v2_2547', 'drugName': 'Phentolamine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRA1A (ENSG00000120907), ADRA2A (ENSG00000150594), ADRA2C (ENSG00000184160), ADRA1D (ENSG00000171873), ADRA1B (ENSG00000170214), ADRA2B (ENSG00000274286)', 'yearOfFirstApproval': 1952, 'm... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1933 | Q59 | What is the genetic target of the small molecule drug Chloroprocaine, and what is its status in clinical trials and FDA approval? | There are 10 genetic targets of the small molecule drug Chloroprocaine: SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. Chloroprocaine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%chloroprocaine%" OR LOWER(tradeNames_string) LIKE "%chloroprocaine%"... | [{'UUID': 'DrugGeneTargets_v2_1606', 'drugName': 'Chloroprocaine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SCN1A (ENSG00000144285), SCN5A (ENSG00000183873), SCN4A (ENSG00000007314), SCN7A (ENSG00000136546), SCN2A (ENSG00000136531), SCN9A (ENSG00000169432), SCN3A (ENSG00000153253), SCN11A (ENS... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1367 | Q59 | What is the genetic target of the small molecule drug Naquotinib, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Naquotinib is EGFR. Naquotinib reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%naquotinib%" OR LOWER(tradeNames_string) LIKE "%naquotinib%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_3137', 'drugName': 'Naquotinib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'EGFR (ENSG00000146648)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1444 | Q59 | What is the genetic target of the small molecule drug Cinacalcet, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Cinacalcet is CASR. Cinacalcet reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%cinacalcet%" OR LOWER(tradeNames_string) LIKE "%cinacalcet%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_841', 'drugName': 'Cinacalcet Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CASR (ENSG00000036828)', 'yearOfFirstApproval': 2004, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_247', 'drugName': 'Cinacalcet', 'drugMole... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.178 | Q59 | What is the genetic target of the small molecule drug Amphetamine Adipate, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Amphetamine Adipate: SLC6A2 and SLC6A3. Amphetamine Adipate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%amphetamine adipate%" OR LOWER(tradeNames_string) LIKE "%amphetamine... | [{'UUID': 'DrugGeneTargets_v2_3242', 'drugName': 'Dextroamphetamine Adipate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC18A2 (ENSG00000165646), SLC6A2 (ENSG00000103546), SLC6A3 (ENSG00000142319)', 'yearOfFirstApproval': 1975, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'Dru... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.470 | Q59 | What is the genetic target of the small molecule drug Tamsulosin Hydrochloride, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Tamsulosin Hydrochloride: ADRA1A, ADRA1D, and ADRA1B. Tamsulosin Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tamsulosin hydrochloride%" OR LOWER(tradeNames_string) LIKE "%tamsul... | [{'UUID': 'DrugGeneTargets_v2_5784', 'drugName': 'Tamsulosin Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRA1A (ENSG00000120907), ADRA1D (ENSG00000171873), ADRA1B (ENSG00000170214)', 'yearOfFirstApproval': 1997, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1337 | Q59 | What is the genetic target of the oligosaccharide drug Heparin Sodium, and what is its status in clinical trials and FDA approval? | The genetic target of the oligosaccharide drug Heparin Sodium is SERPINC1. Heparin Sodium reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%heparin sodium%" OR LOWER(tradeNames_string) LIKE "%heparin sodium%"... | [{'UUID': 'DrugGeneTargets_v2_4090', 'drugName': 'Heparin Sodium', 'drugMolecularType': 'Oligosaccharide', 'newLinkedTargets_string': 'SERPINC1 (ENSG00000117601)', 'yearOfFirstApproval': 1939, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1611 | Q59 | What is the genetic target of the small molecule drug Etodolac, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Etodolac is PTGS2. Etodolac reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%etodolac%" OR LOWER(tradeNames_string) LIKE "%etodolac%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_916', 'drugName': 'Etodolac', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGS2 (ENSG00000073756)', 'yearOfFirstApproval': 1991, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4358', 'drugName': 'Sdx-101', 'drugMolecularType': 'Smal... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.126 | Q59 | What is the genetic target of the small molecule drug Cp-459632, and what is its status in clinical trials and FDA approval? | There are 8 genetic targets of the small molecule drug Cp-459632: TIE1, FLT1, FLT4, KDR, FGFR3, FGFR1, FGFR4, and FGFR2. Cp-459632 reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%cp-459632%" OR LOWER(tradeNames_string) LIKE "%cp-459632%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_1414', 'drugName': 'Cp-459632', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TIE1 (ENSG00000066056), FLT1 (ENSG00000102755), FLT4 (ENSG00000037280), KDR (ENSG00000128052), FGFR3 (ENSG00000068078), FGFR1 (ENSG00000077782), FGFR4 (ENSG00000160867), FGFR2 (ENSG0000006646... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.355 | Q59 | What is the genetic target of the small molecule drug Nomifensine Maleate, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Nomifensine Maleate: SLC6A4, SLC6A3, and SLC6A2. Nomifensine Maleate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%nomifensine maleate%" OR LOWER(tradeNames_string) LIKE "%nomifensine... | [{'UUID': 'DrugGeneTargets_v2_2665', 'drugName': 'Nomifensine Maleate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A4 (ENSG00000108576), SLC6A3 (ENSG00000142319), SLC6A2 (ENSG00000103546)', 'yearOfFirstApproval': 1984, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.388 | Q59 | What is the genetic target of the small molecule drug Nintedanib Esylate, and what is its status in clinical trials and FDA approval? | There are 9 genetic targets of the small molecule drug Nintedanib Esylate: FLT1, FLT4, KDR, FGFR3, FGFR1, FGFR4, FGFR2, PDGFRB, and PDGFRA. Nintedanib Esylate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%nintedanib esylate%" OR LOWER(tradeNames_string) LIKE "%nintedanib e... | [{'UUID': 'DrugGeneTargets_v2_4523', 'drugName': 'Nintedanib Esylate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'FLT1 (ENSG00000102755), FLT4 (ENSG00000037280), KDR (ENSG00000128052), FGFR3 (ENSG00000068078), FGFR1 (ENSG00000077782), FGFR4 (ENSG00000160867), FGFR2 (ENSG00000066468), PDGFRB (ENS... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1435 | Q59 | What is the genetic target of the small molecule drug Nomegestrol, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Nomegestrol is PGR. Nomegestrol reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%nomegestrol%" OR LOWER(tradeNames_string) LIKE "%nomegestrol%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_3771', 'drugName': 'Nomegestrol', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PGR (ENSG00000082175)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1760', 'drugName': 'Nomegestrol Acetate', 'drugMolecularT... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1007 | Q59 | What is the genetic target of the small molecule drug Pf-04447943, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Pf-04447943 is PDE9A. Pf-04447943 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%pf-04447943%" OR LOWER(tradeNames_string) LIKE "%pf-04447943%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_3337', 'drugName': 'Pf-04447943', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PDE9A (ENSG00000160191)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.894 | Q59 | What is the genetic target of the small molecule drug Propranolol, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Propranolol: ADRB2 and ADRB1. Propranolol reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%propranolol%" OR LOWER(tradeNames_string) LIKE "%propranolol%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_4719', 'drugName': 'Propranolol Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRB2 (ENSG00000169252), ADRB1 (ENSG00000043591)', 'yearOfFirstApproval': 1967, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4718', 'drugN... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1495 | Q59 | What is the genetic target of the antibody drug Tildrakizumab, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the antibody drug Tildrakizumab: IL12B and IL23A. Tildrakizumab reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tildrakizumab%" OR LOWER(tradeNames_string) LIKE "%tildrakizumab%" O... | [{'UUID': 'DrugGeneTargets_v2_1373', 'drugName': 'Tildrakizumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'IL12B (ENSG00000113302), IL23A (ENSG00000110944)', 'yearOfFirstApproval': 2018, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.335 | Q59 | What is the genetic target of the small molecule drug Dihydroergotamine, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Dihydroergotamine is HTR1D. Dihydroergotamine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%dihydroergotamine%" OR LOWER(tradeNames_string) LIKE "%dihydroergota... | [{'UUID': 'DrugGeneTargets_v2_6027', 'drugName': 'Dihydroergotamine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR1D (ENSG00000179546)', 'yearOfFirstApproval': 1946, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_5316', 'drugName': 'Dihydroergotamine Mesylate... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.975 | Q59 | What is the genetic target of the small molecule drug Axomadol, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Axomadol: OPRM1, OPRD1, and OPRK1. Axomadol reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%axomadol%" OR LOWER(tradeNames_string) LIKE "%axomadol%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_1313', 'drugName': 'Axomadol', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'OPRM1 (ENSG00000112038), OPRD1 (ENSG00000116329), OPRK1 (ENSG00000082556)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_1314', ... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.197 | Q59 | What is the genetic target of the small molecule drug Fosaprepitant Dimeglumine, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Fosaprepitant Dimeglumine is TACR1. Fosaprepitant Dimeglumine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%fosaprepitant dimeglumine%" OR LOWER(tradeNames_string) LIKE "%fosap... | [{'UUID': 'DrugGeneTargets_v2_5495', 'drugName': 'Fosaprepitant Dimeglumine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TACR1 (ENSG00000115353)', 'yearOfFirstApproval': 2008, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.520 | Q59 | What is the genetic target of the small molecule drug Trandolapril, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Trandolapril is ACE. Trandolapril reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%trandolapril%" OR LOWER(tradeNames_string) LIKE "%trandolapril%" OR ... | [{'UUID': 'DrugGeneTargets_v2_3055', 'drugName': 'Trandolapril', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ACE (ENSG00000159640)', 'yearOfFirstApproval': 1996, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.459 | Q59 | What is the genetic target of the small molecule drug Begacestat, and what is its status in clinical trials and FDA approval? | There are 6 genetic targets of the small molecule drug Begacestat: APH1A, PSENEN, APH1B, PSEN1, NCSTN, and PSEN2. Begacestat reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%begacestat%" OR LOWER(tradeNames_string) LIKE "%begacestat%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_6270', 'drugName': 'Begacestat', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'APH1A (ENSG00000117362), PSENEN (ENSG00000205155), APH1B (ENSG00000138613), PSEN1 (ENSG00000080815), NCSTN (ENSG00000162736), PSEN2 (ENSG00000143801)', 'yearOfFirstApproval': 0, 'maxClinical... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1714 | Q59 | What is the genetic target of the small molecule drug Epinephrine Bitartrate, and what is its status in clinical trials and FDA approval? | There are 9 genetic targets of the small molecule drug Epinephrine Bitartrate: ADRA1A, ADRA2A, ADRB1, ADRB2, ADRA2C, ADRA1D, ADRA1B, ADRA2B, and ADRB3. Epinephrine Bitartrate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%epinephrine bitartrate%" OR LOWER(tradeNames_string) LIKE "%epinephr... | [{'UUID': 'DrugGeneTargets_v2_1843', 'drugName': 'Norepinephrine Bitartrate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRA1A (ENSG00000120907), ADRA2A (ENSG00000150594), ADRB1 (ENSG00000043591), ADRB2 (ENSG00000169252), ADRA2C (ENSG00000184160), ADRA1D (ENSG00000171873), ADRA1B (ENSG000001702... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.326 | Q59 | What is the genetic target of the small molecule drug Dexamethasone Phosphoric Acid, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Dexamethasone Phosphoric Acid is NR3C1. Dexamethasone Phosphoric Acid reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%dexamethasone phosphoric acid%" OR LOWER(tradeNames_string) LIKE "%d... | [{'UUID': 'DrugGeneTargets_v2_4269', 'drugName': 'Dexamethasone Phosphoric Acid', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'NR3C1 (ENSG00000113580)', 'yearOfFirstApproval': 1959, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1323 | Q59 | What is the genetic target of the protein drug Txa127, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Txa127 is MAS1. Txa127 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%txa127%" OR LOWER(tradeNames_string) LIKE "%txa127%" OR LOWER(drugSy... | [{'UUID': 'DrugGeneTargets_v2_2902', 'drugName': 'Txa127', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'MAS1 (ENSG00000130368)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.269 | Q59 | What is the genetic target of the small molecule drug Alectinib Hydrochloride, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Alectinib Hydrochloride: ALK, RET, and EML4. Alectinib Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%alectinib hydrochloride%" OR LOWER(tradeNames_string) LIKE "%alectin... | [{'UUID': 'DrugGeneTargets_v2_1249', 'drugName': 'Alectinib Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ALK (ENSG00000171094), RET (ENSG00000165731), EML4 (ENSG00000143924)', 'yearOfFirstApproval': 2015, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTarget... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.799 | Q59 | What is the genetic target of the small molecule drug Nitrefazole, and what is its status in clinical trials and FDA approval? | There are 7 genetic targets of the small molecule drug Nitrefazole: ADH1A, ADH4, ADH1B, ADH1C, ADH7, ADH5, and ADH6. Nitrefazole reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%nitrefazole%" OR LOWER(tradeNames_string) LIKE "%nitrefazole%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_6344', 'drugName': 'Nitrefazole', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADH1A (ENSG00000187758), ADH4 (ENSG00000198099), ADH1B (ENSG00000196616), ADH1C (ENSG00000248144), ADH7 (ENSG00000196344), ADH5 (ENSG00000197894), ADH6 (ENSG00000172955)', 'yearOfFirstAppro... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1432 | Q59 | What is the genetic target of the small molecule drug Isoproterenol Sulfate, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Isoproterenol Sulfate: ADRB1, ADRB2, and ADRB3. Isoproterenol Sulfate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%isoproterenol sulfate%" OR LOWER(tradeNames_string) LIKE "%isoproter... | [{'UUID': 'DrugGeneTargets_v2_5769', 'drugName': 'Isoproterenol Sulfate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRB1 (ENSG00000043591), ADRB2 (ENSG00000169252), ADRB3 (ENSG00000188778)', 'yearOfFirstApproval': 1956, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.70 | Q59 | What is the genetic target of the small molecule drug Levobetaxolol, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Levobetaxolol is ADRB1. Levobetaxolol reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%levobetaxolol%" OR LOWER(tradeNames_string) LIKE "%levobetaxolol%" O... | [{'UUID': 'DrugGeneTargets_v2_2237', 'drugName': 'Levobetaxolol Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRB1 (ENSG00000043591)', 'yearOfFirstApproval': 2000, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_6023', 'drugName': 'Levobetaxolol', ... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.938 | Q59 | What is the genetic target of the small molecule drug Fenofibric Acid, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Fenofibric Acid is PPARA. Fenofibric Acid reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%fenofibric acid%" OR LOWER(tradeNames_string) LIKE "%fenofibric acid... | [{'UUID': 'DrugGeneTargets_v2_347', 'drugName': 'Fenofibric Acid', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PPARA (ENSG00000186951)', 'yearOfFirstApproval': 2008, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4196', 'drugName': 'Choline Fenofibrate', 'drugMo... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1447 | Q59 | What is the genetic target of the small molecule drug Estetrol, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Estetrol: ESR2 and ESR1. Estetrol reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%estetrol%" OR LOWER(tradeNames_string) LIKE "%estetrol%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_4568', 'drugName': 'Estetrol', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ESR2 (ENSG00000140009), ESR1 (ENSG00000091831)', 'yearOfFirstApproval': 2021, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1782 | Q59 | What is the genetic target of the oligonucleotide drug Imetelstat Sodium, and what is its status in clinical trials and FDA approval? | The genetic target of the oligonucleotide drug Imetelstat Sodium is TERT. Imetelstat Sodium reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%imetelstat sodium%" OR LOWER(tradeNames_string) LIKE "%imetelstat so... | [{'UUID': 'DrugGeneTargets_v2_403', 'drugName': 'Imetelstat Sodium', 'drugMolecularType': 'Oligonucleotide', 'newLinkedTargets_string': 'TERT (ENSG00000164362)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.468 | Q59 | What is the genetic target of the small molecule drug Fenfluramine, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Fenfluramine: HTR1D, SIGMAR1, and HTR2C. Fenfluramine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%fenfluramine%" OR LOWER(tradeNames_string) LIKE "%fenfluramine%" OR ... | [{'UUID': 'DrugGeneTargets_v2_3888', 'drugName': 'Fenfluramine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR2C (ENSG00000147246), HTR1D (ENSG00000179546), SIGMAR1 (ENSG00000147955)', 'yearOfFirstApproval': 2020, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'Drug... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1396 | Q59 | What is the genetic target of the small molecule drug Setipiprant, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Setipiprant is PTGDR2. Setipiprant reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%setipiprant%" OR LOWER(tradeNames_string) LIKE "%setipiprant%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_3585', 'drugName': 'Setipiprant', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGDR2 (ENSG00000183134)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1614 | Q59 | What is the genetic target of the small molecule drug Penbutolol, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Penbutolol: ADRB1 and ADRB2. Penbutolol reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%penbutolol%" OR LOWER(tradeNames_string) LIKE "%penbutolol%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_3766', 'drugName': 'Penbutolol', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRB1 (ENSG00000043591), ADRB2 (ENSG00000169252)', 'yearOfFirstApproval': 1987, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3765', 'drugName': 'Penbutol... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.549 | Q59 | What is the genetic target of the small molecule drug Cp-195543, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Cp-195543: LTB4R2 and LTB4R. Cp-195543 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%cp-195543%" OR LOWER(tradeNames_string) LIKE "%cp-195543%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_193', 'drugName': 'Cp-195543', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'LTB4R2 (ENSG00000213906), LTB4R (ENSG00000213903)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.538 | Q59 | What is the genetic target of the protein drug Insulin Zinc Susp Purified Beef, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Insulin Zinc Susp Purified Beef is INSR. Insulin Zinc Susp Purified Beef reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%insulin zinc susp purified beef%" OR LOWER(tradeNames_string) LIKE "... | [{'UUID': 'DrugGeneTargets_v2_2997', 'drugName': 'Insulin Zinc Susp Purified Beef', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'INSR (ENSG00000171105)', 'yearOfFirstApproval': 1980, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2821', 'drugName': 'Insulin Zinc Susp Pu... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1230 | Q59 | What is the genetic target of the small molecule drug Benazepril Hydrochloride, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Benazepril Hydrochloride is ACE. Benazepril Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%benazepril hydrochloride%" OR LOWER(tradeNames_string) LIKE "%benaze... | [{'UUID': 'DrugGeneTargets_v2_5353', 'drugName': 'Benazepril Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ACE (ENSG00000159640)', 'yearOfFirstApproval': 1991, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.957 | Q59 | What is the genetic target of the small molecule drug Tak-653, and what is its status in clinical trials and FDA approval? | There are 4 genetic targets of the small molecule drug Tak-653: GRIA4, GRIA3, GRIA2, and GRIA1. Tak-653 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tak-653%" OR LOWER(tradeNames_string) LIKE "%tak-653%" OR LOWER(drug... | [{'UUID': 'DrugGeneTargets_v2_2292', 'drugName': 'Tak-653', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'GRIA4 (ENSG00000152578), GRIA3 (ENSG00000125675), GRIA2 (ENSG00000120251), GRIA1 (ENSG00000155511)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1635 | Q59 | What is the genetic target of the antibody drug Amg-888, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Amg-888 is ERBB3. Amg-888 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%amg-888%" OR LOWER(tradeNames_string) LIKE "%amg-888%" OR LOWER(drug... | [{'UUID': 'DrugGeneTargets_v2_3653', 'drugName': 'Amg-888', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'ERBB3 (ENSG00000065361)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1418 | Q59 | What is the genetic target of the small molecule drug Sotorasib, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Sotorasib is KRAS. Sotorasib reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%sotorasib%" OR LOWER(tradeNames_string) LIKE "%sotorasib%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_1834', 'drugName': 'Sotorasib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'KRAS (ENSG00000133703)', 'yearOfFirstApproval': 2021, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
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