uuid stringlengths 4 8 | template_uuid stringclasses 40
values | question stringlengths 13 193 | answer stringlengths 29 2.2k | benchmark_query stringlengths 133 622 | execution_results stringlengths 2 1.14M | query_type stringclasses 2
values | sql_category stringclasses 26
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Q59.422 | Q59 | What is the genetic target of the small molecule drug Desoxycorticosterone Pivalate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Desoxycorticosterone Pivalate is NR3C2. Desoxycorticosterone Pivalate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%desoxycorticosterone pivalate%" OR LOWER(tradeNames_string) LIKE "%d... | [{'UUID': 'DrugGeneTargets_v2_3356', 'drugName': 'Desoxycorticosterone Pivalate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'NR3C2 (ENSG00000151623)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1935 | Q59 | What is the genetic target of the small molecule drug Dorzolamide, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Dorzolamide is CA2. Dorzolamide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%dorzolamide%" OR LOWER(tradeNames_string) LIKE "%dorzolamide%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_333', 'drugName': 'Dorzolamide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CA2 (ENSG00000104267)', 'yearOfFirstApproval': 1994, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1719', 'drugName': 'Dorzolamide Hydrochloride', 'drugMo... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1532 | Q59 | What is the genetic target of the small molecule drug Sibutramine Hydrochloride, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Sibutramine Hydrochloride: SLC6A4, SLC6A3, and SLC6A2. Sibutramine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%sibutramine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%sibut... | [{'UUID': 'DrugGeneTargets_v2_2809', 'drugName': 'Sibutramine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A4 (ENSG00000108576), SLC6A3 (ENSG00000142319), SLC6A2 (ENSG00000103546)', 'yearOfFirstApproval': 1997, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1580 | Q59 | What is the genetic target of the small molecule drug Evogliptin, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Evogliptin is DPP4. Evogliptin reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%evogliptin%" OR LOWER(tradeNames_string) LIKE "%evogliptin%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_1447', 'drugName': 'Evogliptin', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DPP4 (ENSG00000197635)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1659 | Q59 | What is the genetic target of the small molecule drug Doxycycline Calcium, and what is its status in clinical trials and FDA approval? | There are 4 genetic targets of the small molecule drug Doxycycline Calcium: MMP1, MMP13, MMP7, and MMP8. Doxycycline Calcium reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%doxycycline calcium%" OR LOWER(tradeNames_string) LIKE "%doxycycline... | [{'UUID': 'DrugGeneTargets_v2_5150', 'drugName': 'Doxycycline Calcium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'MMP1 (ENSG00000196611), MMP13 (ENSG00000137745), MMP7 (ENSG00000137673), MMP8 (ENSG00000118113)', 'yearOfFirstApproval': 1974, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1116 | Q59 | What is the genetic target of the small molecule drug Sertraline, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Sertraline is SLC6A4. Sertraline reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%sertraline%" OR LOWER(tradeNames_string) LIKE "%sertraline%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_464', 'drugName': 'Sertraline Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A4 (ENSG00000108576)', 'yearOfFirstApproval': 1991, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_514', 'drugName': 'Sertraline', 'drugMo... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.722 | Q59 | What is the genetic target of the small molecule drug Mivavotinib Citrate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Mivavotinib Citrate is SYK. Mivavotinib Citrate reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%mivavotinib citrate%" OR LOWER(tradeNames_string) LIKE "%mivavotinib... | [{'UUID': 'DrugGeneTargets_v2_4579', 'drugName': 'Mivavotinib Citrate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SYK (ENSG00000165025)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1247 | Q59 | What is the genetic target of the small molecule drug Pseudoephedrine, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Pseudoephedrine is SLC6A2. Pseudoephedrine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%pseudoephedrine%" OR LOWER(tradeNames_string) LIKE "%pseudoephedrine... | [{'UUID': 'DrugGeneTargets_v2_1353', 'drugName': 'Pseudoephedrine Sulfate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A2 (ENSG00000103546)', 'yearOfFirstApproval': 1963, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_5086', 'drugName': 'Pseudoephedrine', '... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1236 | Q59 | What is the genetic target of the small molecule drug Estropipate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Estropipate is ESR1. Estropipate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%estropipate%" OR LOWER(tradeNames_string) LIKE "%estropipate%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_2257', 'drugName': 'Estropipate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ESR1 (ENSG00000091831)', 'yearOfFirstApproval': 1977, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1076 | Q59 | What is the genetic target of the small molecule drug Samidorphan, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Samidorphan: OPRK1, OPRM1, and OPRD1. Samidorphan reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%samidorphan%" OR LOWER(tradeNames_string) LIKE "%samidorphan%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_4533', 'drugName': 'Samidorphan', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'OPRK1 (ENSG00000082556), OPRM1 (ENSG00000112038), OPRD1 (ENSG00000116329)', 'yearOfFirstApproval': 2021, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_45... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1907 | Q59 | What is the genetic target of the small molecule drug Drf-10945, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Drf-10945 is PPARA. Drf-10945 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%drf-10945%" OR LOWER(tradeNames_string) LIKE "%drf-10945%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_627', 'drugName': 'Drf-10945', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PPARA (ENSG00000186951)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.264 | Q59 | What is the genetic target of the antibody drug Pimurutamab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Pimurutamab is EGFR. Pimurutamab reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%pimurutamab%" OR LOWER(tradeNames_string) LIKE "%pimurutamab%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_2484', 'drugName': 'Pimurutamab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'EGFR (ENSG00000146648)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1437 | Q59 | What is the genetic target of the small molecule drug Pentaerythritol Tetranitrate, and what is its status in clinical trials and FDA approval? | There are 4 genetic targets of the small molecule drug Pentaerythritol Tetranitrate: GUCY1B1, GUCY1B2, GUCY1A2, and GUCY1A1. Pentaerythritol Tetranitrate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%pentaerythritol tetranitrate%" OR LOWER(tradeNames_string) LIKE "%pe... | [{'UUID': 'DrugGeneTargets_v2_31', 'drugName': 'Pentaerythritol Tetranitrate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'GUCY1B1 (ENSG00000061918), GUCY1B2 (ENSG00000123201), GUCY1A2 (ENSG00000152402), GUCY1A1 (ENSG00000164116)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsAppr... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1339 | Q59 | What is the genetic target of the small molecule drug Histamine, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Histamine is HRH1. Histamine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%histamine%" OR LOWER(tradeNames_string) LIKE "%histamine%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_2616', 'drugName': 'Histamine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH1 (ENSG00000196639)', 'yearOfFirstApproval': 1939, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2637', 'drugName': 'Terfenadine', 'drugMolecularType': ... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.243 | Q59 | What is the genetic target of the antibody drug Omalizumab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Omalizumab is IGHE. Omalizumab reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%omalizumab%" OR LOWER(tradeNames_string) LIKE "%omalizumab%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_6216', 'drugName': 'Omalizumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'IGHE (ENSG00000211891)', 'yearOfFirstApproval': 2003, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1010 | Q59 | What is the genetic target of the small molecule drug Mycophenolate Sodium, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Mycophenolate Sodium: IMPDH1 and IMPDH2. Mycophenolate Sodium reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%mycophenolate sodium%" OR LOWER(tradeNames_string) LIKE "%mycophenol... | [{'UUID': 'DrugGeneTargets_v2_2561', 'drugName': 'Mycophenolate Sodium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'IMPDH1 (ENSG00000106348), IMPDH2 (ENSG00000178035)', 'yearOfFirstApproval': 2004, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.685 | Q59 | What is the genetic target of the antibody drug Cdp-850, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Cdp-850 is SELE. Cdp-850 reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%cdp-850%" OR LOWER(tradeNames_string) LIKE "%cdp-850%" OR LOWER(drug... | [{'UUID': 'DrugGeneTargets_v2_5392', 'drugName': 'Cdp-850', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'SELE (ENSG00000007908)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1268 | Q59 | What is the genetic target of the protein drug Pegcetacoplan, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Pegcetacoplan is C3. Pegcetacoplan reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%pegcetacoplan%" OR LOWER(tradeNames_string) LIKE "%pegcetacoplan%" O... | [{'UUID': 'DrugGeneTargets_v2_4931', 'drugName': 'Pegcetacoplan', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'C3 (ENSG00000125730)', 'yearOfFirstApproval': 2021, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1475 | Q59 | What is the genetic target of the small molecule drug Parecoxib Sodium, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Parecoxib Sodium is PTGS2. Parecoxib Sodium reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%parecoxib sodium%" OR LOWER(tradeNames_string) LIKE "%parecoxib sodi... | [{'UUID': 'DrugGeneTargets_v2_2672', 'drugName': 'Parecoxib Sodium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGS2 (ENSG00000073756)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1502 | Q59 | What is the genetic target of the small molecule drug Betazole Hydrochloride, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Betazole Hydrochloride is HRH2. Betazole Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%betazole hydrochloride%" OR LOWER(tradeNames_string) LIKE "%betazole... | [{'UUID': 'DrugGeneTargets_v2_3149', 'drugName': 'Betazole Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH2 (ENSG00000113749)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.370 | Q59 | What is the genetic target of the small molecule drug Procainamide Hydrochloride, and what is its status in clinical trials and FDA approval? | There are 10 genetic targets of the small molecule drug Procainamide Hydrochloride: SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. Procainamide Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%procainamide hydrochloride%" OR LOWER(tradeNames_string) LIKE "%proc... | [{'UUID': 'DrugGeneTargets_v2_4967', 'drugName': 'Procainamide Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SCN1A (ENSG00000144285), SCN5A (ENSG00000183873), SCN4A (ENSG00000007314), SCN7A (ENSG00000136546), SCN2A (ENSG00000136531), SCN9A (ENSG00000169432), SCN3A (ENSG00000153253),... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1009 | Q59 | What is the genetic target of the small molecule drug Bucindolol Hydrochloride, and what is its status in clinical trials and FDA approval? | There are 5 genetic targets of the small molecule drug Bucindolol Hydrochloride: ADRB1, ADRA1A, ADRA1D, ADRA1B, and ADRB2. Bucindolol Hydrochloride reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%bucindolol hydrochloride%" OR LOWER(tradeNames_string) LIKE "%bucind... | [{'UUID': 'DrugGeneTargets_v2_4949', 'drugName': 'Bucindolol Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRB1 (ENSG00000043591), ADRA1A (ENSG00000120907), ADRA1D (ENSG00000171873), ADRA1B (ENSG00000170214), ADRB2 (ENSG00000169252)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhas... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1239 | Q59 | What is the genetic target of the small molecule drug Pentolinium, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Pentolinium: CHRNB4 and CHRNA3. Pentolinium reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%pentolinium%" OR LOWER(tradeNames_string) LIKE "%pentolinium%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_4468', 'drugName': 'Pentolinium Tartrate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRNB4 (ENSG00000117971), CHRNA3 (ENSG00000080644)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4982', 'drugName... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.595 | Q59 | What is the genetic target of the small molecule drug Serabelisib, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Serabelisib is PIK3CA. Serabelisib reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%serabelisib%" OR LOWER(tradeNames_string) LIKE "%serabelisib%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_5452', 'drugName': 'Serabelisib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PIK3CA (ENSG00000121879)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.728 | Q59 | What is the genetic target of the protein drug Insulin Zinc Susp Prompt Beef, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Insulin Zinc Susp Prompt Beef is INSR. Insulin Zinc Susp Prompt Beef reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%insulin zinc susp prompt beef%" OR LOWER(tradeNames_string) LIKE "%i... | [{'UUID': 'DrugGeneTargets_v2_3871', 'drugName': 'Insulin Zinc Susp Prompt Beef', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'INSR (ENSG00000171105)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.486 | Q59 | What is the genetic target of the oligonucleotide drug Casimersen, and what is its status in clinical trials and FDA approval? | The genetic target of the oligonucleotide drug Casimersen is DMD. Casimersen reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%casimersen%" OR LOWER(tradeNames_string) LIKE "%casimersen%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_4498', 'drugName': 'Casimersen', 'drugMolecularType': 'Oligonucleotide', 'newLinkedTargets_string': 'DMD (ENSG00000198947)', 'yearOfFirstApproval': 2021, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.573 | Q59 | What is the genetic target of the small molecule drug Bicalutamide, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Bicalutamide is AR. Bicalutamide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%bicalutamide%" OR LOWER(tradeNames_string) LIKE "%bicalutamide%" OR ... | [{'UUID': 'DrugGeneTargets_v2_2718', 'drugName': 'Bicalutamide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'AR (ENSG00000169083)', 'yearOfFirstApproval': 1995, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.74 | Q59 | What is the genetic target of the small molecule drug Ramipril, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Ramipril is ACE. Ramipril reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ramipril%" OR LOWER(tradeNames_string) LIKE "%ramipril%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_6072', 'drugName': 'Ramipril', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ACE (ENSG00000159640)', 'yearOfFirstApproval': 1991, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.635 | Q59 | What is the genetic target of the small molecule drug Odevixibat, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Odevixibat is SLC10A2. Odevixibat reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%odevixibat%" OR LOWER(tradeNames_string) LIKE "%odevixibat%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_1281', 'drugName': 'Odevixibat', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC10A2 (ENSG00000125255)', 'yearOfFirstApproval': 2021, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.262 | Q59 | What is the genetic target of the protein drug Avexitide, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Avexitide is GLP1R. Avexitide reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%avexitide%" OR LOWER(tradeNames_string) LIKE "%avexitide%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_1357', 'drugName': 'Avexitide', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'GLP1R (ENSG00000112164)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.52 | Q59 | What is the genetic target of the small molecule drug Meloxicam, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Meloxicam is PTGS2. Meloxicam reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%meloxicam%" OR LOWER(tradeNames_string) LIKE "%meloxicam%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_988', 'drugName': 'Meloxicam', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGS2 (ENSG00000073756)', 'yearOfFirstApproval': 2000, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.201 | Q59 | What is the genetic target of the small molecule drug Rg-547, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Rg-547: CDK2, CDK4, and CDK1. Rg-547 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%rg-547%" OR LOWER(tradeNames_string) LIKE "%rg-547%" OR LOWER(drugSy... | [{'UUID': 'DrugGeneTargets_v2_4371', 'drugName': 'Rg-547', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CDK2 (ENSG00000123374), CDK4 (ENSG00000135446), CDK1 (ENSG00000170312)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_4372', 'drug... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.432 | Q59 | What is the genetic target of the small molecule drug Tak-593, and what is its status in clinical trials and FDA approval? | There are 5 genetic targets of the small molecule drug Tak-593: PDGFRB, PDGFRA, FLT1, FLT4, and KDR. Tak-593 reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tak-593%" OR LOWER(tradeNames_string) LIKE "%tak-593%" OR LOWER(drug... | [{'UUID': 'DrugGeneTargets_v2_3813', 'drugName': 'Tak-593', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PDGFRB (ENSG00000113721), PDGFRA (ENSG00000134853), FLT1 (ENSG00000102755), FLT4 (ENSG00000037280), KDR (ENSG00000128052)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1563 | Q59 | What is the genetic target of the small molecule drug Benzphetamine, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Benzphetamine: SLC6A2 and SLC18A2. Benzphetamine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%benzphetamine%" OR LOWER(tradeNames_string) LIKE "%benzphetamine%" O... | [{'UUID': 'DrugGeneTargets_v2_168', 'drugName': 'Benzphetamine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A2 (ENSG00000103546), SLC18A2 (ENSG00000165646)', 'yearOfFirstApproval': 1960, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_167', 'dr... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.336 | Q59 | What is the genetic target of the small molecule drug Ns-2359, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Ns-2359: SLC6A4, SLC6A3, and SLC6A2. Ns-2359 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ns-2359%" OR LOWER(tradeNames_string) LIKE "%ns-2359%" OR LOWER(drug... | [{'UUID': 'DrugGeneTargets_v2_5369', 'drugName': 'Ns-2359', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A4 (ENSG00000108576), SLC6A3 (ENSG00000142319), SLC6A2 (ENSG00000103546)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1557 | Q59 | What is the genetic target of the antibody drug Ontuxizumab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Ontuxizumab is CD248. Ontuxizumab reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ontuxizumab%" OR LOWER(tradeNames_string) LIKE "%ontuxizumab%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_2763', 'drugName': 'Ontuxizumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'CD248 (ENSG00000174807)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1539 | Q59 | What is the genetic target of the small molecule drug Ethopropazine Hydrochloride, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Ethopropazine Hydrochloride is CHRM1. Ethopropazine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ethopropazine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%eth... | [{'UUID': 'DrugGeneTargets_v2_3507', 'drugName': 'Ethopropazine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRM1 (ENSG00000168539)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.426 | Q59 | What is the genetic target of the antibody drug Khk-2866, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Khk-2866 is HBEGF. Khk-2866 reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%khk-2866%" OR LOWER(tradeNames_string) LIKE "%khk-2866%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_5685', 'drugName': 'Khk-2866', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'HBEGF (ENSG00000113070)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.637 | Q59 | What is the genetic target of the small molecule drug Mipsagargin, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Mipsagargin: ATP2A3, ATP2A1, and ATP2A2. Mipsagargin reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%mipsagargin%" OR LOWER(tradeNames_string) LIKE "%mipsagargin%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_3997', 'drugName': 'Mipsagargin', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ATP2A3 (ENSG00000074370), ATP2A1 (ENSG00000196296), ATP2A2 (ENSG00000174437)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.941 | Q59 | What is the genetic target of the antibody drug Lumretuzumab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Lumretuzumab is ERBB3. Lumretuzumab reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%lumretuzumab%" OR LOWER(tradeNames_string) LIKE "%lumretuzumab%" OR ... | [{'UUID': 'DrugGeneTargets_v2_3820', 'drugName': 'Lumretuzumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'ERBB3 (ENSG00000065361)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.993 | Q59 | What is the genetic target of the antibody drug Galcanezumab, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the antibody drug Galcanezumab: CALCA and CALCB. Galcanezumab reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%galcanezumab%" OR LOWER(tradeNames_string) LIKE "%galcanezumab%" OR ... | [{'UUID': 'DrugGeneTargets_v2_1901', 'drugName': 'Galcanezumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'CALCA (ENSG00000110680), CALCB (ENSG00000175868)', 'yearOfFirstApproval': 2018, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.868 | Q59 | What is the genetic target of the small molecule drug Rg7342, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Rg7342 is GRM5. Rg7342 reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%rg7342%" OR LOWER(tradeNames_string) LIKE "%rg7342%" OR LOWER(drugSy... | [{'UUID': 'DrugGeneTargets_v2_2228', 'drugName': 'Rg7342', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'GRM5 (ENSG00000168959)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1951 | Q59 | What is the genetic target of the small molecule drug Tulobuterol, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Tulobuterol is ADRB2. Tulobuterol reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tulobuterol%" OR LOWER(tradeNames_string) LIKE "%tulobuterol%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_6208', 'drugName': 'Tulobuterol', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRB2 (ENSG00000169252)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.558 | Q59 | What is the genetic target of the small molecule drug Irx-4204, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Irx-4204: RXRB, RXRG, and RXRA. Irx-4204 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%irx-4204%" OR LOWER(tradeNames_string) LIKE "%irx-4204%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_633', 'drugName': 'Irx-4204', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'RXRB (ENSG00000204231), RXRG (ENSG00000143171), RXRA (ENSG00000186350)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.433 | Q59 | What is the genetic target of the small molecule drug Dexamethasone Acetate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Dexamethasone Acetate is NR3C1. Dexamethasone Acetate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%dexamethasone acetate%" OR LOWER(tradeNames_string) LIKE "%dexametha... | [{'UUID': 'DrugGeneTargets_v2_4777', 'drugName': 'Dexamethasone Acetate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'NR3C1 (ENSG00000113580)', 'yearOfFirstApproval': 1973, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1777 | Q59 | What is the genetic target of the small molecule drug Carboprost Tromethamine, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Carboprost Tromethamine is PTGFR. Carboprost Tromethamine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%carboprost tromethamine%" OR LOWER(tradeNames_string) LIKE "%carbopr... | [{'UUID': 'DrugGeneTargets_v2_2928', 'drugName': 'Carboprost Tromethamine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGFR (ENSG00000122420)', 'yearOfFirstApproval': 1979, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1834 | Q59 | What is the genetic target of the small molecule drug Samotolisib, and what is its status in clinical trials and FDA approval? | There are 9 genetic targets of the small molecule drug Samotolisib: MTOR, PIK3R1, PIK3CB, PIK3CG, PIK3CA, PIK3R2, PIK3CD, PIK3R5, and PIK3R3. Samotolisib reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%samotolisib%" OR LOWER(tradeNames_string) LIKE "%samotolisib%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_2319', 'drugName': 'Samotolisib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'MTOR (ENSG00000198793), PIK3R1 (ENSG00000145675), PIK3CB (ENSG00000051382), PIK3CG (ENSG00000105851), PIK3CA (ENSG00000121879), PIK3R2 (ENSG00000105647), PIK3CD (ENSG00000171608), PIK3R5 (E... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1977 | Q59 | What is the genetic target of the small molecule drug Nalbuphine Hydrochloride, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Nalbuphine Hydrochloride: OPRK1, OPRD1, and OPRM1. Nalbuphine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%nalbuphine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%nalbup... | [{'UUID': 'DrugGeneTargets_v2_1991', 'drugName': 'Nalbuphine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'OPRK1 (ENSG00000082556), OPRD1 (ENSG00000116329), OPRM1 (ENSG00000112038)', 'yearOfFirstApproval': 1979, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1506 | Q59 | What is the genetic target of the protein drug Epoetin Beta, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Epoetin Beta is EPOR. Epoetin Beta reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%epoetin beta%" OR LOWER(tradeNames_string) LIKE "%epoetin beta%" OR ... | [{'UUID': 'DrugGeneTargets_v2_4530', 'drugName': 'Methoxy Polyethylene Glycol-Epoetin Beta', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'EPOR (ENSG00000187266)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3185', 'drugName': 'Epoetin Beta',... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1622 | Q59 | What is the genetic target of the small molecule drug Palonosetron, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Palonosetron is HTR3A. Palonosetron reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%palonosetron%" OR LOWER(tradeNames_string) LIKE "%palonosetron%" OR ... | [{'UUID': 'DrugGeneTargets_v2_4389', 'drugName': 'Palonosetron', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR3A (ENSG00000166736)', 'yearOfFirstApproval': 2003, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3577', 'drugName': 'Palonosetron Hydrochloride', 'd... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.404 | Q59 | What is the genetic target of the small molecule drug Pexidartinib, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Pexidartinib: FLT3, KIT, and CSF1R. Pexidartinib reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%pexidartinib%" OR LOWER(tradeNames_string) LIKE "%pexidartinib%" OR ... | [{'UUID': 'DrugGeneTargets_v2_4379', 'drugName': 'Pexidartinib Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'KIT (ENSG00000157404), FLT3 (ENSG00000122025), CSF1R (ENSG00000182578)', 'yearOfFirstApproval': 2019, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneT... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1791 | Q59 | What is the genetic target of the small molecule drug Bimatoprost, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Bimatoprost is PTGFR. Bimatoprost reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%bimatoprost%" OR LOWER(tradeNames_string) LIKE "%bimatoprost%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_704', 'drugName': 'Bimatoprost', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGFR (ENSG00000122420)', 'yearOfFirstApproval': 2001, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.195 | Q59 | What is the genetic target of the protein drug Angiotensin Ii Acetate, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Angiotensin Ii Acetate is AGTR1. Angiotensin Ii Acetate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%angiotensin ii acetate%" OR LOWER(tradeNames_string) LIKE "%angioten... | [{'UUID': 'DrugGeneTargets_v2_3664', 'drugName': 'Angiotensin Ii Acetate', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'AGTR1 (ENSG00000144891)', 'yearOfFirstApproval': 2017, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1281 | Q59 | What is the genetic target of the small molecule drug Lasmiditan, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Lasmiditan is HTR1F. Lasmiditan reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%lasmiditan%" OR LOWER(tradeNames_string) LIKE "%lasmiditan%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_4144', 'drugName': 'Lasmiditan', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR1F (ENSG00000179097)', 'yearOfFirstApproval': 2020, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1894', 'drugName': 'Lasmiditan Succinate', 'drugMolec... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1381 | Q59 | What is the genetic target of the small molecule drug Acemetacin, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Acemetacin: PTGS2 and PTGS1. Acemetacin reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%acemetacin%" OR LOWER(tradeNames_string) LIKE "%acemetacin%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_3840', 'drugName': 'Acemetacin', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGS2 (ENSG00000073756), PTGS1 (ENSG00000095303)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.677 | Q59 | What is the genetic target of the small molecule drug Liothyronine Sodium, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Liothyronine Sodium: THRA and THRB. Liothyronine Sodium reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%liothyronine sodium%" OR LOWER(tradeNames_string) LIKE "%liothyronin... | [{'UUID': 'DrugGeneTargets_v2_4914', 'drugName': 'Liothyronine Sodium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'THRA (ENSG00000126351), THRB (ENSG00000151090)', 'yearOfFirstApproval': 1956, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.795 | Q59 | What is the genetic target of the small molecule drug Trilostane, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Trilostane is HSD3B2. Trilostane reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%trilostane%" OR LOWER(tradeNames_string) LIKE "%trilostane%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_2278', 'drugName': 'Trilostane', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HSD3B2 (ENSG00000203859)', 'yearOfFirstApproval': 1984, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1463 | Q59 | What is the genetic target of the small molecule drug Aclidinium, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Aclidinium is CHRM3. Aclidinium reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%aclidinium%" OR LOWER(tradeNames_string) LIKE "%aclidinium%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_6136', 'drugName': 'Aclidinium Bromide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRM3 (ENSG00000133019)', 'yearOfFirstApproval': 2012, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4890', 'drugName': 'Aclidinium', 'drugMolecul... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1457 | Q59 | What is the genetic target of the small molecule drug Midodrine, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Midodrine: ADRA1A, ADRA1D, and ADRA1B. Midodrine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%midodrine%" OR LOWER(tradeNames_string) LIKE "%midodrine%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_5117', 'drugName': 'Midodrine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRA1A (ENSG00000120907), ADRA1D (ENSG00000171873), ADRA1B (ENSG00000170214)', 'yearOfFirstApproval': 1996, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGe... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.144 | Q59 | What is the genetic target of the small molecule drug Meperidine, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Meperidine is OPRM1. Meperidine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%meperidine%" OR LOWER(tradeNames_string) LIKE "%meperidine%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_497', 'drugName': 'Meperidine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'OPRM1 (ENSG00000112038)', 'yearOfFirstApproval': 1942, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1463', 'drugName': 'Meperidine', 'drugMo... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1188 | Q59 | What is the genetic target of the small molecule drug Tramadol, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Tramadol is OPRM1. Tramadol reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tramadol%" OR LOWER(tradeNames_string) LIKE "%tramadol%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_5530', 'drugName': 'Tramadol', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'OPRM1 (ENSG00000112038)', 'yearOfFirstApproval': 1995, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3268', 'drugName': 'Tramadol Hydrochloride', 'drugMolec... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.3 | Q59 | What is the genetic target of the small molecule drug Avanafil, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Avanafil is PDE5A. Avanafil reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%avanafil%" OR LOWER(tradeNames_string) LIKE "%avanafil%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_5497', 'drugName': 'Avanafil', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PDE5A (ENSG00000138735)', 'yearOfFirstApproval': 2011, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.743 | Q59 | What is the genetic target of the small molecule drug Lofexidine Hydrochloride, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Lofexidine Hydrochloride: ADRA2A, ADRA2C, and ADRA2B. Lofexidine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%lofexidine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%lofexi... | [{'UUID': 'DrugGeneTargets_v2_3056', 'drugName': 'Lofexidine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRA2A (ENSG00000150594), ADRA2C (ENSG00000184160), ADRA2B (ENSG00000274286)', 'yearOfFirstApproval': 2018, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1871 | Q59 | What is the genetic target of the protein drug Ctce-9908, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Ctce-9908 is CXCR4. Ctce-9908 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ctce-9908%" OR LOWER(tradeNames_string) LIKE "%ctce-9908%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_626', 'drugName': 'Ctce-9908', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'CXCR4 (ENSG00000121966)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1516 | Q59 | What is the genetic target of the small molecule drug Fluphenazine Decanoate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Fluphenazine Decanoate is DRD2. Fluphenazine Decanoate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%fluphenazine decanoate%" OR LOWER(tradeNames_string) LIKE "%fluphena... | [{'UUID': 'DrugGeneTargets_v2_432', 'drugName': 'Fluphenazine Decanoate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DRD2 (ENSG00000149295)', 'yearOfFirstApproval': 1972, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.343 | Q59 | What is the genetic target of the small molecule drug Galicaftor, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Galicaftor is CFTR. Galicaftor reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%galicaftor%" OR LOWER(tradeNames_string) LIKE "%galicaftor%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_5544', 'drugName': 'Galicaftor', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CFTR (ENSG00000001626)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.626 | Q59 | What is the genetic target of the antibody drug Sgn-30, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Sgn-30 is TNFRSF8. Sgn-30 reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%sgn-30%" OR LOWER(tradeNames_string) LIKE "%sgn-30%" OR LOWER(drugSy... | [{'UUID': 'DrugGeneTargets_v2_1085', 'drugName': 'Brentuximab Vedotin', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'TNFRSF8 (ENSG00000120949), TUBB4B (ENSG00000188229), TUBB1 (ENSG00000101162), TUBA3C (ENSG00000198033), TUBA4A (ENSG00000127824), TUBB3 (ENSG00000258947), TUBA1A (ENSG00000167552), TUBB4A... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.484 | Q59 | What is the genetic target of the small molecule drug Codeine, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Codeine: OPRK1, OPRD1, and OPRM1. Codeine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%codeine%" OR LOWER(tradeNames_string) LIKE "%codeine%" OR LOWER(drug... | [{'UUID': 'DrugGeneTargets_v2_3666', 'drugName': 'Codeine Sulfate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'OPRK1 (ENSG00000082556), OPRD1 (ENSG00000116329), OPRM1 (ENSG00000112038)', 'yearOfFirstApproval': 2009, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.532 | Q59 | What is the genetic target of the antibody drug Domvanalimab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Domvanalimab is TIGIT. Domvanalimab reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%domvanalimab%" OR LOWER(tradeNames_string) LIKE "%domvanalimab%" OR ... | [{'UUID': 'DrugGeneTargets_v2_2184', 'drugName': 'Domvanalimab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'TIGIT (ENSG00000181847)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.268 | Q59 | What is the genetic target of the small molecule drug Lubiprostone, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Lubiprostone is CLCN2. Lubiprostone reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%lubiprostone%" OR LOWER(tradeNames_string) LIKE "%lubiprostone%" OR ... | [{'UUID': 'DrugGeneTargets_v2_3388', 'drugName': 'Lubiprostone', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CLCN2 (ENSG00000114859)', 'yearOfFirstApproval': 2006, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1390 | Q59 | What is the genetic target of the small molecule drug Ethylestrenol, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Ethylestrenol is AR. Ethylestrenol reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ethylestrenol%" OR LOWER(tradeNames_string) LIKE "%ethylestrenol%" O... | [{'UUID': 'DrugGeneTargets_v2_3566', 'drugName': 'Ethylestrenol', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'AR (ENSG00000169083)', 'yearOfFirstApproval': 1964, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.681 | Q59 | What is the genetic target of the small molecule drug Bilastine, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Bilastine is HRH1. Bilastine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%bilastine%" OR LOWER(tradeNames_string) LIKE "%bilastine%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_1236', 'drugName': 'Bilastine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH1 (ENSG00000196639)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.492 | Q59 | What is the genetic target of the small molecule drug Azaribine, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Azaribine is UMPS. Azaribine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%azaribine%" OR LOWER(tradeNames_string) LIKE "%azaribine%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_5699', 'drugName': 'Azaribine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'UMPS (ENSG00000114491)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.445 | Q59 | What is the genetic target of the protein drug Lypressin, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the protein drug Lypressin: AVPR2, AVPR1A, and AVPR1B. Lypressin reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%lypressin%" OR LOWER(tradeNames_string) LIKE "%lypressin%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_5948', 'drugName': 'Terlipressin', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'AVPR1A (ENSG00000166148), AVPR1B (ENSG00000198049), AVPR2 (ENSG00000126895)', 'yearOfFirstApproval': 2022, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3226',... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.274 | Q59 | What is the genetic target of the small molecule drug Dinaciclib, and what is its status in clinical trials and FDA approval? | There are 4 genetic targets of the small molecule drug Dinaciclib: CDK5, CDK1, CDK9, and CDK2. Dinaciclib reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%dinaciclib%" OR LOWER(tradeNames_string) LIKE "%dinaciclib%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_47', 'drugName': 'Dinaciclib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CDK5 (ENSG00000164885), CDK1 (ENSG00000170312), CDK9 (ENSG00000136807), CDK2 (ENSG00000123374)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}, {'UUID': 'DrugG... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.187 | Q59 | What is the genetic target of the small molecule drug Gsk-461364, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Gsk-461364 is PLK1. Gsk-461364 reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%gsk-461364%" OR LOWER(tradeNames_string) LIKE "%gsk-461364%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_2668', 'drugName': 'Gsk-461364', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PLK1 (ENSG00000166851)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.950 | Q59 | What is the genetic target of the antibody drug Bapineuzumab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Bapineuzumab is APP. Bapineuzumab reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%bapineuzumab%" OR LOWER(tradeNames_string) LIKE "%bapineuzumab%" OR ... | [{'UUID': 'DrugGeneTargets_v2_3737', 'drugName': 'Bapineuzumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'APP (ENSG00000142192)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.247 | Q59 | What is the genetic target of the small molecule drug Vibegron, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Vibegron is ADRB3. Vibegron reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%vibegron%" OR LOWER(tradeNames_string) LIKE "%vibegron%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_9', 'drugName': 'Vibegron', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRB3 (ENSG00000188778)', 'yearOfFirstApproval': 2020, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1100 | Q59 | What is the genetic target of the small molecule drug Enarodustat, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Enarodustat is EGLN1. Enarodustat reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%enarodustat%" OR LOWER(tradeNames_string) LIKE "%enarodustat%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_2978', 'drugName': 'Enarodustat', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'EGLN1 (ENSG00000135766)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1018 | Q59 | What is the genetic target of the small molecule drug Protriptyline Hydrochloride, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Protriptyline Hydrochloride: SLC6A2 and SLC6A4. Protriptyline Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%protriptyline hydrochloride%" OR LOWER(tradeNames_string) LIKE "%pro... | [{'UUID': 'DrugGeneTargets_v2_5492', 'drugName': 'Protriptyline Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A2 (ENSG00000103546), SLC6A4 (ENSG00000108576)', 'yearOfFirstApproval': 1967, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_5493', 'd... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.590 | Q59 | What is the genetic target of the small molecule drug Tranexamic Acid, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Tranexamic Acid is PLG. Tranexamic Acid reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tranexamic acid%" OR LOWER(tradeNames_string) LIKE "%tranexamic acid... | [{'UUID': 'DrugGeneTargets_v2_5780', 'drugName': 'Tranexamic Acid', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PLG (ENSG00000122194)', 'yearOfFirstApproval': 1986, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1629 | Q59 | What is the genetic target of the small molecule drug Hydroxychloroquine Sulfate, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Hydroxychloroquine Sulfate: TLR9 and TLR7. Hydroxychloroquine Sulfate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%hydroxychloroquine sulfate%" OR LOWER(tradeNames_string) LIKE "%hydr... | [{'UUID': 'DrugGeneTargets_v2_3878', 'drugName': 'Hydroxychloroquine Sulfate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TLR9 (ENSG00000239732), TLR7 (ENSG00000196664)', 'yearOfFirstApproval': 1955, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3879', 'drugNa... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.535 | Q59 | What is the genetic target of the small molecule drug Anisotropine Methylbromide, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Anisotropine Methylbromide: CHRM1 and CHRM3. Anisotropine Methylbromide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%anisotropine methylbromide%" OR LOWER(tradeNames_string) LIKE "%anis... | [{'UUID': 'DrugGeneTargets_v2_6145', 'drugName': 'Anisotropine Methylbromide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRM1 (ENSG00000168539), CHRM3 (ENSG00000133019)', 'yearOfFirstApproval': 1962, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_6146', 'drug... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.899 | Q59 | What is the genetic target of the small molecule drug Lesinurad, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Lesinurad is SLC22A12. Lesinurad reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%lesinurad%" OR LOWER(tradeNames_string) LIKE "%lesinurad%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_1001', 'drugName': 'Lesinurad', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC22A12 (ENSG00000197891)', 'yearOfFirstApproval': 2015, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1483 | Q59 | What is the genetic target of the small molecule drug Mevidalen, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Mevidalen is DRD1. Mevidalen reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%mevidalen%" OR LOWER(tradeNames_string) LIKE "%mevidalen%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_5395', 'drugName': 'Mevidalen', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DRD1 (ENSG00000184845)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1109 | Q59 | What is the genetic target of the small molecule drug Fentanyl Citrate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Fentanyl Citrate is OPRM1. Fentanyl Citrate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%fentanyl citrate%" OR LOWER(tradeNames_string) LIKE "%fentanyl citra... | [{'UUID': 'DrugGeneTargets_v2_733', 'drugName': 'Fentanyl Citrate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'OPRM1 (ENSG00000112038)', 'yearOfFirstApproval': 1968, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.421 | Q59 | What is the genetic target of the small molecule drug Tolvaptan, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Tolvaptan is AVPR2. Tolvaptan reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tolvaptan%" OR LOWER(tradeNames_string) LIKE "%tolvaptan%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_5028', 'drugName': 'Tolvaptan', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'AVPR2 (ENSG00000126895)', 'yearOfFirstApproval': 2009, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.277 | Q59 | What is the genetic target of the small molecule drug Ergotamine, and what is its status in clinical trials and FDA approval? | There are 7 genetic targets of the small molecule drug Ergotamine: HTR1D, ADRA1A, ADRA2A, ADRA2C, ADRA1D, ADRA1B, and ADRA2B. Ergotamine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ergotamine%" OR LOWER(tradeNames_string) LIKE "%ergotamine%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_3132', 'drugName': 'Ergotamine Tartrate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRA1A (ENSG00000120907), ADRA2A (ENSG00000150594), ADRA2C (ENSG00000184160), ADRA1D (ENSG00000171873), ADRA1B (ENSG00000170214), ADRA2B (ENSG00000274286), HTR1D (ENSG00000179546)',... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1174 | Q59 | What is the genetic target of the small molecule drug Etoricoxib, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Etoricoxib is PTGS2. Etoricoxib reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%etoricoxib%" OR LOWER(tradeNames_string) LIKE "%etoricoxib%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_1741', 'drugName': 'Etoricoxib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGS2 (ENSG00000073756)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1487 | Q59 | What is the genetic target of the small molecule drug Rabeprazole Sodium, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Rabeprazole Sodium: ATP4A and ATP4B. Rabeprazole Sodium reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%rabeprazole sodium%" OR LOWER(tradeNames_string) LIKE "%rabeprazole ... | [{'UUID': 'DrugGeneTargets_v2_5144', 'drugName': 'Rabeprazole Sodium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ATP4A (ENSG00000105675), ATP4B (ENSG00000186009)', 'yearOfFirstApproval': 1999, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1456 | Q59 | What is the genetic target of the small molecule drug Firsocostat, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Firsocostat: ACACA and ACACB. Firsocostat reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%firsocostat%" OR LOWER(tradeNames_string) LIKE "%firsocostat%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_2565', 'drugName': 'Firsocostat', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ACACA (ENSG00000278540), ACACB (ENSG00000076555)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.253 | Q59 | What is the genetic target of the small molecule drug Pemetrexed Disodium, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Pemetrexed Disodium: TYMS, DHFR, and GART. Pemetrexed Disodium reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%pemetrexed disodium%" OR LOWER(tradeNames_string) LIKE "%pemetrexed ... | [{'UUID': 'DrugGeneTargets_v2_3690', 'drugName': 'Pemetrexed Disodium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TYMS (ENSG00000176890), DHFR (ENSG00000228716), GART (ENSG00000159131)', 'yearOfFirstApproval': 2004, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.419 | Q59 | What is the genetic target of the antibody drug Tositumomab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Tositumomab is MS4A1. Tositumomab reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tositumomab%" OR LOWER(tradeNames_string) LIKE "%tositumomab%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_5886', 'drugName': 'Tositumomab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'MS4A1 (ENSG00000156738)', 'yearOfFirstApproval': 2003, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2569', 'drugName': 'Tositumomab 131I', 'drugMolecularType'... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1590 | Q59 | What is the genetic target of the small molecule drug Selpercatinib, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Selpercatinib: RET, CCDC6, and KIF5B. Selpercatinib reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%selpercatinib%" OR LOWER(tradeNames_string) LIKE "%selpercatinib%" O... | [{'UUID': 'DrugGeneTargets_v2_896', 'drugName': 'Selpercatinib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'RET (ENSG00000165731), CCDC6 (ENSG00000108091), KIF5B (ENSG00000170759)', 'yearOfFirstApproval': 2020, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_897... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1895 | Q59 | What is the genetic target of the small molecule drug Iloprost, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Iloprost is PTGIR. Iloprost reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%iloprost%" OR LOWER(tradeNames_string) LIKE "%iloprost%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_1577', 'drugName': 'Iloprost', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGIR (ENSG00000160013)', 'yearOfFirstApproval': 2004, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.582 | Q59 | What is the genetic target of the antibody drug Cdp-860, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Cdp-860 is PDGFRB. Cdp-860 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%cdp-860%" OR LOWER(tradeNames_string) LIKE "%cdp-860%" OR LOWER(drug... | [{'UUID': 'DrugGeneTargets_v2_556', 'drugName': 'Cdp-860', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'PDGFRB (ENSG00000113721)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.314 | Q59 | What is the genetic target of the small molecule drug Netupitant, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Netupitant is TACR1. Netupitant reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%netupitant%" OR LOWER(tradeNames_string) LIKE "%netupitant%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_1207', 'drugName': 'Netupitant', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TACR1 (ENSG00000115353)', 'yearOfFirstApproval': 2014, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1941', 'drugName': 'Fosnetupitant', 'drugMolecularTyp... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1962 | Q59 | What is the genetic target of the antibody drug Intetumumab, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the antibody drug Intetumumab: ITGAV, ITGB5, and ITGB3. Intetumumab reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%intetumumab%" OR LOWER(tradeNames_string) LIKE "%intetumumab%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_3000', 'drugName': 'Intetumumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'ITGAV (ENSG00000138448), ITGB5 (ENSG00000082781), ITGB3 (ENSG00000259207)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_3001', 'dr... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.387 | Q59 | What is the genetic target of the small molecule drug Phentermine Hydrochloride, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Phentermine Hydrochloride is SLC6A2. Phentermine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%phentermine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%phent... | [{'UUID': 'DrugGeneTargets_v2_5704', 'drugName': 'Phentermine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A2 (ENSG00000103546)', 'yearOfFirstApproval': 1973, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4353', 'drugName': 'Chlorphentermine ... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.541 | Q59 | What is the genetic target of the protein drug Insulin Pork, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Insulin Pork is INSR. Insulin Pork reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%insulin pork%" OR LOWER(tradeNames_string) LIKE "%insulin pork%" OR ... | [{'UUID': 'DrugGeneTargets_v2_5466', 'drugName': 'Insulin Pork', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'INSR (ENSG00000171105)', 'yearOfFirstApproval': 1966, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
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