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Q59.431
Q59
What is the genetic target of the small molecule drug Lornoxicam, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Lornoxicam: PTGS2 and PTGS1. Lornoxicam reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%lornoxicam%" OR LOWER(tradeNames_string) LIKE "%lornoxicam%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_5752', 'drugName': 'Lornoxicam', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGS2 (ENSG00000073756), PTGS1 (ENSG00000095303)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.657
Q59
What is the genetic target of the protein drug Somatropin, and what is its status in clinical trials and FDA approval?
The genetic target of the protein drug Somatropin is GHR. Somatropin reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%somatropin%" OR LOWER(tradeNames_string) LIKE "%somatropin%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_5635', 'drugName': 'Somatropin', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'GHR (ENSG00000112964)', 'yearOfFirstApproval': 1976, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3230', 'drugName': 'Somatrogon', 'drugMolecularType': 'Protein...
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Q59.1642
Q59
What is the genetic target of the small molecule drug Felbamate, and what is its status in clinical trials and FDA approval?
There are 7 genetic targets of the small molecule drug Felbamate: GRIN1, GRIN2A, GRIN2B, GRIN2D, GRIN3B, GRIN2C, and GRIN3A. Felbamate reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%felbamate%" OR LOWER(tradeNames_string) LIKE "%felbamate%" OR LOWER(...
[{'UUID': 'DrugGeneTargets_v2_758', 'drugName': 'Felbamate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'GRIN1 (ENSG00000176884), GRIN2A (ENSG00000183454), GRIN2B (ENSG00000273079), GRIN2D (ENSG00000105464), GRIN3B (ENSG00000116032), GRIN2C (ENSG00000161509), GRIN3A (ENSG00000198785)', 'yearOfFir...
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Q59.1318
Q59
What is the genetic target of the small molecule drug Pheniramine Maleate, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Pheniramine Maleate is HRH1. Pheniramine Maleate reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%pheniramine maleate%" OR LOWER(tradeNames_string) LIKE "%pheniramine...
[{'UUID': 'DrugGeneTargets_v2_463', 'drugName': 'Pheniramine Maleate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH1 (ENSG00000196639)', 'yearOfFirstApproval': 1994, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_221', 'drugName': 'Chlorpheniramine Maleate', ...
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Q59.1358
Q59
What is the genetic target of the protein drug .Alpha.1-Proteinase Inhibitor Human, and what is its status in clinical trials and FDA approval?
The genetic target of the protein drug .Alpha.1-Proteinase Inhibitor Human is ELANE. .Alpha.1-Proteinase Inhibitor Human reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%.alpha.1-proteinase inhibitor human%" OR LOWER(tradeNames_string) LI...
[{'UUID': 'DrugGeneTargets_v2_2772', 'drugName': '.Alpha.1-Proteinase Inhibitor Human', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'ELANE (ENSG00000197561)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.414
Q59
What is the genetic target of the small molecule drug Zoledronic Acid, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Zoledronic Acid is FDPS. Zoledronic Acid reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%zoledronic acid%" OR LOWER(tradeNames_string) LIKE "%zoledronic acid...
[{'UUID': 'DrugGeneTargets_v2_4706', 'drugName': 'Zoledronic Acid', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'FDPS (ENSG00000160752)', 'yearOfFirstApproval': 2001, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1615
Q59
What is the genetic target of the small molecule drug Crizotinib, and what is its status in clinical trials and FDA approval?
There are 4 genetic targets of the small molecule drug Crizotinib: MET, ALK, NPM1, and EML4. Crizotinib reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%crizotinib%" OR LOWER(tradeNames_string) LIKE "%crizotinib%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_5879', 'drugName': 'Crizotinib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'MET (ENSG00000105976), ALK (ENSG00000171094), NPM1 (ENSG00000181163), EML4 (ENSG00000143924)', 'yearOfFirstApproval': 2011, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'Dru...
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Q59.687
Q59
What is the genetic target of the small molecule drug Birinapant, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Birinapant: BIRC3 and BIRC2. Birinapant reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%birinapant%" OR LOWER(tradeNames_string) LIKE "%birinapant%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_267', 'drugName': 'Birinapant', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'BIRC3 (ENSG00000023445), BIRC2 (ENSG00000110330)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}]
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Q59.621
Q59
What is the genetic target of the small molecule drug Cediranib, and what is its status in clinical trials and FDA approval?
There are 6 genetic targets of the small molecule drug Cediranib: FLT1, FLT4, KDR, KIT, PDGFRB, and PDGFRA. Cediranib reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%cediranib%" OR LOWER(tradeNames_string) LIKE "%cediranib%" OR LOWER(...
[{'UUID': 'DrugGeneTargets_v2_948', 'drugName': 'Cediranib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'FLT1 (ENSG00000102755), FLT4 (ENSG00000037280), KDR (ENSG00000128052), KIT (ENSG00000157404), PDGFRB (ENSG00000113721), PDGFRA (ENSG00000134853)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPh...
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Q59.923
Q59
What is the genetic target of the small molecule drug Daunorubicin, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Daunorubicin is TOP2A. Daunorubicin reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%daunorubicin%" OR LOWER(tradeNames_string) LIKE "%daunorubicin%" OR ...
[{'UUID': 'DrugGeneTargets_v2_1919', 'drugName': 'Daunorubicin Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TOP2A (ENSG00000131747)', 'yearOfFirstApproval': 1979, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_484', 'drugName': 'Doxorubicin', 'dru...
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Q59.1199
Q59
What is the genetic target of the small molecule drug Bromfenac Sodium, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Bromfenac Sodium: PTGS2 and PTGS1. Bromfenac Sodium reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%bromfenac sodium%" OR LOWER(tradeNames_string) LIKE "%bromfenac sodi...
[{'UUID': 'DrugGeneTargets_v2_989', 'drugName': 'Bromfenac Sodium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGS2 (ENSG00000073756), PTGS1 (ENSG00000095303)', 'yearOfFirstApproval': 1997, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.839
Q59
What is the genetic target of the small molecule drug Irinotecan Hydrochloride, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Irinotecan Hydrochloride is TOP1. Irinotecan Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%irinotecan hydrochloride%" OR LOWER(tradeNames_string) LIKE "%irinot...
[{'UUID': 'DrugGeneTargets_v2_5193', 'drugName': 'Irinotecan Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TOP1 (ENSG00000198900)', 'yearOfFirstApproval': 1996, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1771
Q59
What is the genetic target of the small molecule drug Propantheline, and what is its status in clinical trials and FDA approval?
There are 3 genetic targets of the small molecule drug Propantheline: CHRM1, CHRM2, and CHRM3. Propantheline reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%propantheline%" OR LOWER(tradeNames_string) LIKE "%propantheline%" O...
[{'UUID': 'DrugGeneTargets_v2_4311', 'drugName': 'Propantheline Bromide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRM3 (ENSG00000133019), CHRM1 (ENSG00000168539), CHRM2 (ENSG00000181072)', 'yearOfFirstApproval': 1953, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTar...
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Q59.953
Q59
What is the genetic target of the small molecule drug Miglustat, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Miglustat is UGCG. Miglustat reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%miglustat%" OR LOWER(tradeNames_string) LIKE "%miglustat%" OR LOWER(...
[{'UUID': 'DrugGeneTargets_v2_5675', 'drugName': 'Miglustat', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'UGCG (ENSG00000148154)', 'yearOfFirstApproval': 2003, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.185
Q59
What is the genetic target of the small molecule drug Nitrendipine, and what is its status in clinical trials and FDA approval?
There are 4 genetic targets of the small molecule drug Nitrendipine: CACNA1C, CACNA1S, CACNA1D, and CACNA1F. Nitrendipine reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%nitrendipine%" OR LOWER(tradeNames_string) LIKE "%nitrendipine%" OR ...
[{'UUID': 'DrugGeneTargets_v2_1575', 'drugName': 'Nitrendipine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CACNA1C (ENSG00000151067), CACNA1S (ENSG00000081248), CACNA1D (ENSG00000157388), CACNA1F (ENSG00000102001)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1072
Q59
What is the genetic target of the small molecule drug Hydromorphone, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Hydromorphone is OPRM1. Hydromorphone reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%hydromorphone%" OR LOWER(tradeNames_string) LIKE "%hydromorphone%" O...
[{'UUID': 'DrugGeneTargets_v2_245', 'drugName': 'Morphine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'OPRM1 (ENSG00000112038)', 'yearOfFirstApproval': 1984, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3034', 'drugName': 'Hydromorphone', 'drugMolecularType':...
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Q59.711
Q59
What is the genetic target of the small molecule drug Anileridine, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Anileridine: OPRM1 and OPRK1. Anileridine reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%anileridine%" OR LOWER(tradeNames_string) LIKE "%anileridine%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_4939', 'drugName': 'Anileridine Phosphate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'OPRM1 (ENSG00000112038), OPRK1 (ENSG00000082556)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1554', 'drugName'...
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Q59.173
Q59
What is the genetic target of the small molecule drug Sivelestat, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Sivelestat is ELANE. Sivelestat reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%sivelestat%" OR LOWER(tradeNames_string) LIKE "%sivelestat%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_3534', 'drugName': 'Sivelestat', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ELANE (ENSG00000197561)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}]
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Q59.296
Q59
What is the genetic target of the small molecule drug Promethazine Hydrochloride, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Promethazine Hydrochloride is HRH1. Promethazine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%promethazine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%prom...
[{'UUID': 'DrugGeneTargets_v2_4426', 'drugName': 'Promethazine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH1 (ENSG00000196639)', 'yearOfFirstApproval': 1951, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.554
Q59
What is the genetic target of the small molecule drug Fluphenazine Enanthate, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Fluphenazine Enanthate is DRD2. Fluphenazine Enanthate reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%fluphenazine enanthate%" OR LOWER(tradeNames_string) LIKE "%fluphena...
[{'UUID': 'DrugGeneTargets_v2_905', 'drugName': 'Fluphenazine Enanthate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DRD2 (ENSG00000149295)', 'yearOfFirstApproval': 1967, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.763
Q59
What is the genetic target of the oligonucleotide drug Inclisiran, and what is its status in clinical trials and FDA approval?
The genetic target of the oligonucleotide drug Inclisiran is PCSK9. Inclisiran reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%inclisiran%" OR LOWER(tradeNames_string) LIKE "%inclisiran%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_859', 'drugName': 'Inclisiran', 'drugMolecularType': 'Oligonucleotide', 'newLinkedTargets_string': 'PCSK9 (ENSG00000169174)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4738', 'drugName': 'Inclisiran Sodium', 'drugMolecularTy...
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Q59.304
Q59
What is the genetic target of the small molecule drug Levobunolol, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Levobunolol: ADRB2 and ADRB1. Levobunolol reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%levobunolol%" OR LOWER(tradeNames_string) LIKE "%levobunolol%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_1444', 'drugName': 'Levobunolol', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRB2 (ENSG00000169252), ADRB1 (ENSG00000043591)', 'yearOfFirstApproval': 1985, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1443', 'drugName': 'Levobun...
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Q59.1878
Q59
What is the genetic target of the small molecule drug Anagrelide Hydrochloride, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Anagrelide Hydrochloride: PDE3A and PDE3B. Anagrelide Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%anagrelide hydrochloride%" OR LOWER(tradeNames_string) LIKE "%anagre...
[{'UUID': 'DrugGeneTargets_v2_350', 'drugName': 'Anagrelide Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PDE3A (ENSG00000172572), PDE3B (ENSG00000152270)', 'yearOfFirstApproval': 1997, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1093
Q59
What is the genetic target of the small molecule drug Proparacaine, and what is its status in clinical trials and FDA approval?
There are 10 genetic targets of the small molecule drug Proparacaine: SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. Proparacaine reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%proparacaine%" OR LOWER(tradeNames_string) LIKE "%proparacaine%" OR ...
[{'UUID': 'DrugGeneTargets_v2_6139', 'drugName': 'Proparacaine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SCN1A (ENSG00000144285), SCN5A (ENSG00000183873), SCN4A (ENSG00000007314), SCN7A (ENSG00000136546), SCN2A (ENSG00000136531), SCN9A (ENSG00000169432), SCN3A (ENSG00000153253), SCN11A (ENSG0...
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Q59.1747
Q59
What is the genetic target of the small molecule drug Treprostinil, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Treprostinil is PTGIR. Treprostinil reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%treprostinil%" OR LOWER(tradeNames_string) LIKE "%treprostinil%" OR ...
[{'UUID': 'DrugGeneTargets_v2_1758', 'drugName': 'Treprostinil', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGIR (ENSG00000160013)', 'yearOfFirstApproval': 2002, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2433', 'drugName': 'Treprostinil Diolamine', 'drugM...
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Q59.1652
Q59
What is the genetic target of the protein drug Insulin Lispro, and what is its status in clinical trials and FDA approval?
The genetic target of the protein drug Insulin Lispro is INSR. Insulin Lispro reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%insulin lispro%" OR LOWER(tradeNames_string) LIKE "%insulin lispro%"...
[{'UUID': 'DrugGeneTargets_v2_578', 'drugName': 'Insulin Lispro', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'INSR (ENSG00000171105)', 'yearOfFirstApproval': 1996, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_5121', 'drugName': 'Insulin Lispro Protamine Recombinant',...
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Q59.914
Q59
What is the genetic target of the protein drug Insulin Lispro Protamine Recombinant, and what is its status in clinical trials and FDA approval?
The genetic target of the protein drug Insulin Lispro Protamine Recombinant is INSR. Insulin Lispro Protamine Recombinant reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%insulin lispro protamine recombinant%" OR LOWER(tradeNames_string) L...
[{'UUID': 'DrugGeneTargets_v2_5121', 'drugName': 'Insulin Lispro Protamine Recombinant', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'INSR (ENSG00000171105)', 'yearOfFirstApproval': 1999, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1932
Q59
What is the genetic target of the antibody drug Natalizumab, and what is its status in clinical trials and FDA approval?
There are 3 genetic targets of the antibody drug Natalizumab: ITGA4, ITGB7, and ITGB1. Natalizumab reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%natalizumab%" OR LOWER(tradeNames_string) LIKE "%natalizumab%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_5015', 'drugName': 'Natalizumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'ITGA4 (ENSG00000115232), ITGB7 (ENSG00000139626), ITGB1 (ENSG00000150093)', 'yearOfFirstApproval': 2004, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_5016', '...
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Q59.275
Q59
What is the genetic target of the small molecule drug Dersimelagon, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Dersimelagon is MC1R. Dersimelagon reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%dersimelagon%" OR LOWER(tradeNames_string) LIKE "%dersimelagon%" OR ...
[{'UUID': 'DrugGeneTargets_v2_935', 'drugName': 'Dersimelagon', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'MC1R (ENSG00000258839)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}]
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Q59.1147
Q59
What is the genetic target of the small molecule drug Triamcinolone, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Triamcinolone is NR3C1. Triamcinolone reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%triamcinolone%" OR LOWER(tradeNames_string) LIKE "%triamcinolone%" O...
[{'UUID': 'DrugGeneTargets_v2_4745', 'drugName': 'Triamcinolone Diacetate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'NR3C1 (ENSG00000113580)', 'yearOfFirstApproval': 1959, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2041', 'drugName': 'Triamcinolone', 'dru...
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Q59.1589
Q59
What is the genetic target of the small molecule drug Asp-3026, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Asp-3026 is ALK. Asp-3026 reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%asp-3026%" OR LOWER(tradeNames_string) LIKE "%asp-3026%" OR LOWER(dr...
[{'UUID': 'DrugGeneTargets_v2_3702', 'drugName': 'Asp-3026', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ALK (ENSG00000171094)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}]
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Q59.700
Q59
What is the genetic target of the small molecule drug Hexafluorenium, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Hexafluorenium is ACHE. Hexafluorenium reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%hexafluorenium%" OR LOWER(tradeNames_string) LIKE "%hexafluorenium%"...
[{'UUID': 'DrugGeneTargets_v2_4011', 'drugName': 'Hexafluorenium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ACHE (ENSG00000087085)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4592', 'drugName': 'Hexafluorenium Bromide', 'drug...
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Q59.1765
Q59
What is the genetic target of the small molecule drug Dipivefrin Hydrochloride, and what is its status in clinical trials and FDA approval?
There are 9 genetic targets of the small molecule drug Dipivefrin Hydrochloride: ADRA1A, ADRA2A, ADRB1, ADRB2, ADRA2C, ADRA1D, ADRA1B, ADRA2B, and ADRB3. Dipivefrin Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%dipivefrin hydrochloride%" OR LOWER(tradeNames_string) LIKE "%dipive...
[{'UUID': 'DrugGeneTargets_v2_1692', 'drugName': 'Dipivefrin Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRA1A (ENSG00000120907), ADRA2A (ENSG00000150594), ADRB1 (ENSG00000043591), ADRB2 (ENSG00000169252), ADRA2C (ENSG00000184160), ADRA1D (ENSG00000171873), ADRA1B (ENSG0000017021...
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Q59.488
Q59
What is the genetic target of the small molecule drug Betaxolol Hydrochloride, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Betaxolol Hydrochloride is ADRB1. Betaxolol Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%betaxolol hydrochloride%" OR LOWER(tradeNames_string) LIKE "%betaxol...
[{'UUID': 'DrugGeneTargets_v2_3151', 'drugName': 'Betaxolol Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRB1 (ENSG00000043591)', 'yearOfFirstApproval': 1985, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2237', 'drugName': 'Levobetaxolol Hydroc...
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Q59.428
Q59
What is the genetic target of the small molecule drug Vonoprazan Fumarate, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Vonoprazan Fumarate: ATP4A and ATP4B. Vonoprazan Fumarate reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%vonoprazan fumarate%" OR LOWER(tradeNames_string) LIKE "%vonoprazan ...
[{'UUID': 'DrugGeneTargets_v2_5640', 'drugName': 'Vonoprazan Fumarate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ATP4A (ENSG00000105675), ATP4B (ENSG00000186009)', 'yearOfFirstApproval': 2022, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.377
Q59
What is the genetic target of the small molecule drug Fexofenadine Hydrochloride, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Fexofenadine Hydrochloride is HRH1. Fexofenadine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%fexofenadine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%fexo...
[{'UUID': 'DrugGeneTargets_v2_1045', 'drugName': 'Fexofenadine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH1 (ENSG00000196639)', 'yearOfFirstApproval': 1996, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1008
Q59
What is the genetic target of the antibody drug Rituximab, and what is its status in clinical trials and FDA approval?
The genetic target of the antibody drug Rituximab is MS4A1. Rituximab reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%rituximab%" OR LOWER(tradeNames_string) LIKE "%rituximab%" OR LOWER(...
[{'UUID': 'DrugGeneTargets_v2_4195', 'drugName': 'Rituximab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'MS4A1 (ENSG00000156738)', 'yearOfFirstApproval': 1997, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1003
Q59
What is the genetic target of the oligonucleotide drug Lumasiran, and what is its status in clinical trials and FDA approval?
The genetic target of the oligonucleotide drug Lumasiran is HAO1. Lumasiran reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%lumasiran%" OR LOWER(tradeNames_string) LIKE "%lumasiran%" OR LOWER(...
[{'UUID': 'DrugGeneTargets_v2_1382', 'drugName': 'Lumasiran', 'drugMolecularType': 'Oligonucleotide', 'newLinkedTargets_string': 'HAO1 (ENSG00000101323)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1071', 'drugName': 'Lumasiran Sodium', 'drugMolecularType...
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Q59.1940
Q59
What is the genetic target of the protein drug Calcitonin Salmon Recombinant, and what is its status in clinical trials and FDA approval?
The genetic target of the protein drug Calcitonin Salmon Recombinant is CALCR. Calcitonin Salmon Recombinant reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%calcitonin salmon recombinant%" OR LOWER(tradeNames_string) LIKE "%c...
[{'UUID': 'DrugGeneTargets_v2_4748', 'drugName': 'Calcitonin Salmon Recombinant', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'CALCR (ENSG00000004948)', 'yearOfFirstApproval': 2005, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.714
Q59
What is the genetic target of the small molecule drug Canagliflozin, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Canagliflozin is SLC5A2. Canagliflozin reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%canagliflozin%" OR LOWER(tradeNames_string) LIKE "%canagliflozin%" O...
[{'UUID': 'DrugGeneTargets_v2_4559', 'drugName': 'Canagliflozin', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC5A2 (ENSG00000140675)', 'yearOfFirstApproval': 2011, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_6346', 'drugName': 'Canagliflozin', 'drugMolecula...
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Q59.1335
Q59
What is the genetic target of the small molecule drug Bitolterol, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Bitolterol is ADRB2. Bitolterol reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%bitolterol%" OR LOWER(tradeNames_string) LIKE "%bitolterol%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_5529', 'drugName': 'Bitolterol', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRB2 (ENSG00000169252)', 'yearOfFirstApproval': 1984, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3535', 'drugName': 'Bitolterol Mesylate', 'drugMolecu...
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Q59.1156
Q59
What is the genetic target of the small molecule drug Bi-811283, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Bi-811283 is AURKB. Bi-811283 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%bi-811283%" OR LOWER(tradeNames_string) LIKE "%bi-811283%" OR LOWER(...
[{'UUID': 'DrugGeneTargets_v2_1351', 'drugName': 'Bi-811283', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'AURKB (ENSG00000178999)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}]
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Q59.338
Q59
What is the genetic target of the small molecule drug Butorphanol Tartrate, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Butorphanol Tartrate: OPRM1 and OPRK1. Butorphanol Tartrate reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%butorphanol tartrate%" OR LOWER(tradeNames_string) LIKE "%butorphano...
[{'UUID': 'DrugGeneTargets_v2_1672', 'drugName': 'Butorphanol Tartrate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'OPRM1 (ENSG00000112038), OPRK1 (ENSG00000082556)', 'yearOfFirstApproval': 1978, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1673', 'drugName':...
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Q59.1343
Q59
What is the genetic target of the small molecule drug Melatonin, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Melatonin: MTNR1A and MTNR1B. Melatonin reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%melatonin%" OR LOWER(tradeNames_string) LIKE "%melatonin%" OR LOWER(...
[{'UUID': 'DrugGeneTargets_v2_5737', 'drugName': 'Melatonin', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'MTNR1A (ENSG00000168412), MTNR1B (ENSG00000134640)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1593
Q59
What is the genetic target of the small molecule drug Cr-6086, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Cr-6086 is PTGER4. Cr-6086 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%cr-6086%" OR LOWER(tradeNames_string) LIKE "%cr-6086%" OR LOWER(drug...
[{'UUID': 'DrugGeneTargets_v2_4531', 'drugName': 'Cr-6086', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGER4 (ENSG00000171522)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}]
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Q59.1993
Q59
What is the genetic target of the small molecule drug Ropinirole Hydrochloride, and what is its status in clinical trials and FDA approval?
There are 3 genetic targets of the small molecule drug Ropinirole Hydrochloride: DRD2, DRD3, and DRD4. Ropinirole Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%ropinirole hydrochloride%" OR LOWER(tradeNames_string) LIKE "%ropini...
[{'UUID': 'DrugGeneTargets_v2_1840', 'drugName': 'Ropinirole Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DRD2 (ENSG00000149295), DRD3 (ENSG00000151577), DRD4 (ENSG00000069696)', 'yearOfFirstApproval': 1997, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.598
Q59
What is the genetic target of the antibody drug Tb-403, and what is its status in clinical trials and FDA approval?
The genetic target of the antibody drug Tb-403 is PGF. Tb-403 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%tb-403%" OR LOWER(tradeNames_string) LIKE "%tb-403%" OR LOWER(drugSy...
[{'UUID': 'DrugGeneTargets_v2_3688', 'drugName': 'Tb-403', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'PGF (ENSG00000119630)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}]
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Q59.16
Q59
What is the genetic target of the small molecule drug Baricitinib, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Baricitinib: JAK2 and JAK1. Baricitinib reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%baricitinib%" OR LOWER(tradeNames_string) LIKE "%baricitinib%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_1303', 'drugName': 'Baricitinib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'JAK2 (ENSG00000096968), JAK1 (ENSG00000162434)', 'yearOfFirstApproval': 2018, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1304', 'drugName': 'Baricitin...
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Q59.1855
Q59
What is the genetic target of the small molecule drug Silodosin, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Silodosin is ADRA1A. Silodosin reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%silodosin%" OR LOWER(tradeNames_string) LIKE "%silodosin%" OR LOWER(...
[{'UUID': 'DrugGeneTargets_v2_557', 'drugName': 'Silodosin', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRA1A (ENSG00000120907)', 'yearOfFirstApproval': 2008, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1634
Q59
What is the genetic target of the small molecule drug Molindone, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Molindone: HTR2A and DRD2. Molindone reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%molindone%" OR LOWER(tradeNames_string) LIKE "%molindone%" OR LOWER(...
[{'UUID': 'DrugGeneTargets_v2_789', 'drugName': 'Molindone', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR2A (ENSG00000102468), DRD2 (ENSG00000149295)', 'yearOfFirstApproval': 1974, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_788', 'drugName': 'Molindone', ...
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Q59.1686
Q59
What is the genetic target of the small molecule drug Acetyldigitoxin, and what is its status in clinical trials and FDA approval?
There are 8 genetic targets of the small molecule drug Acetyldigitoxin: ATP1A1, ATP1B2, ATP1B1, ATP1A2, ATP1B3, ATP1A3, ATP1A4, and FXYD2. Acetyldigitoxin reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%acetyldigitoxin%" OR LOWER(tradeNames_string) LIKE "%acetyldigitoxin...
[{'UUID': 'DrugGeneTargets_v2_1212', 'drugName': 'Acetyldigitoxin', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ATP1A1 (ENSG00000163399), ATP1B2 (ENSG00000129244), ATP1B1 (ENSG00000143153), ATP1A2 (ENSG00000018625), ATP1B3 (ENSG00000069849), ATP1A3 (ENSG00000105409), ATP1A4 (ENSG00000132681), FXY...
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Q59.600
Q59
What is the genetic target of the protein drug Plecanatide, and what is its status in clinical trials and FDA approval?
The genetic target of the protein drug Plecanatide is GUCY2C. Plecanatide reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%plecanatide%" OR LOWER(tradeNames_string) LIKE "%plecanatide%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_5758', 'drugName': 'Plecanatide', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'GUCY2C (ENSG00000070019)', 'yearOfFirstApproval': 2017, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.924
Q59
What is the genetic target of the small molecule drug Sitaxentan Sodium, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Sitaxentan Sodium: EDNRB and EDNRA. Sitaxentan Sodium reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%sitaxentan sodium%" OR LOWER(tradeNames_string) LIKE "%sitaxentan so...
[{'UUID': 'DrugGeneTargets_v2_5500', 'drugName': 'Sitaxentan Sodium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'EDNRB (ENSG00000136160), EDNRA (ENSG00000151617)', 'yearOfFirstApproval': 2006, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.471
Q59
What is the genetic target of the small molecule drug Propoxycaine Hydrochloride, and what is its status in clinical trials and FDA approval?
There are 10 genetic targets of the small molecule drug Propoxycaine Hydrochloride: SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. Propoxycaine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%propoxycaine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%prop...
[{'UUID': 'DrugGeneTargets_v2_1701', 'drugName': 'Propoxycaine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SCN1A (ENSG00000144285), SCN5A (ENSG00000183873), SCN4A (ENSG00000007314), SCN7A (ENSG00000136546), SCN2A (ENSG00000136531), SCN9A (ENSG00000169432), SCN3A (ENSG00000153253),...
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Q59.202
Q59
What is the genetic target of the small molecule drug Ticlopidine, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Ticlopidine is P2RY12. Ticlopidine reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%ticlopidine%" OR LOWER(tradeNames_string) LIKE "%ticlopidine%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_3795', 'drugName': 'Ticlopidine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'P2RY12 (ENSG00000169313)', 'yearOfFirstApproval': 1991, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1201', 'drugName': 'Ticlopidine Hydrochloride', 'dr...
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Q59.1206
Q59
What is the genetic target of the protein drug Tesamorelin, and what is its status in clinical trials and FDA approval?
The genetic target of the protein drug Tesamorelin is GHRHR. Tesamorelin reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%tesamorelin%" OR LOWER(tradeNames_string) LIKE "%tesamorelin%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_2825', 'drugName': 'Tesamorelin', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'GHRHR (ENSG00000106128)', 'yearOfFirstApproval': 2010, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4100', 'drugName': 'Tesamorelin Acetate', 'drugMolecularTyp...
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Q59.1056
Q59
What is the genetic target of the small molecule drug Qaf805, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Qaf805: ADORA3 and ADORA2B. Qaf805 reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%qaf805%" OR LOWER(tradeNames_string) LIKE "%qaf805%" OR LOWER(drugSy...
[{'UUID': 'DrugGeneTargets_v2_5644', 'drugName': 'Qaf805', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADORA3 (ENSG00000282608), ADORA2B (ENSG00000170425)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_5645', 'drugName': 'Qaf805', 'd...
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Q59.1195
Q59
What is the genetic target of the small molecule drug Sertraline Hydrochloride, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Sertraline Hydrochloride is SLC6A4. Sertraline Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%sertraline hydrochloride%" OR LOWER(tradeNames_string) LIKE "%sertra...
[{'UUID': 'DrugGeneTargets_v2_464', 'drugName': 'Sertraline Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A4 (ENSG00000108576)', 'yearOfFirstApproval': 1991, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1300
Q59
What is the genetic target of the small molecule drug Fenoldopam Mesylate, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Fenoldopam Mesylate is DRD1. Fenoldopam Mesylate reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%fenoldopam mesylate%" OR LOWER(tradeNames_string) LIKE "%fenoldopam ...
[{'UUID': 'DrugGeneTargets_v2_4006', 'drugName': 'Fenoldopam Mesylate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DRD1 (ENSG00000184845)', 'yearOfFirstApproval': 1997, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1276
Q59
What is the genetic target of the small molecule drug Ketamine Hydrochloride, and what is its status in clinical trials and FDA approval?
There are 7 genetic targets of the small molecule drug Ketamine Hydrochloride: GRIN1, GRIN2A, GRIN2B, GRIN2D, GRIN3B, GRIN2C, and GRIN3A. Ketamine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%ketamine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%ketamine...
[{'UUID': 'DrugGeneTargets_v2_1959', 'drugName': 'Ketamine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'GRIN1 (ENSG00000176884), GRIN2A (ENSG00000183454), GRIN2B (ENSG00000273079), GRIN2D (ENSG00000105464), GRIN3B (ENSG00000116032), GRIN2C (ENSG00000161509), GRIN3A (ENSG00000198785...
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Q59.1814
Q59
What is the genetic target of the antibody drug Tomaralimab, and what is its status in clinical trials and FDA approval?
The genetic target of the antibody drug Tomaralimab is TLR2. Tomaralimab reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%tomaralimab%" OR LOWER(tradeNames_string) LIKE "%tomaralimab%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_5402', 'drugName': 'Tomaralimab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'TLR2 (ENSG00000137462)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}]
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Q59.1402
Q59
What is the genetic target of the small molecule drug Piroxicam, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Piroxicam: PTGS2 and PTGS1. Piroxicam reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%piroxicam%" OR LOWER(tradeNames_string) LIKE "%piroxicam%" OR LOWER(...
[{'UUID': 'DrugGeneTargets_v2_2069', 'drugName': 'Piroxicam', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGS2 (ENSG00000073756), PTGS1 (ENSG00000095303)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1807
Q59
What is the genetic target of the small molecule drug Hydrocodone Bitartrate, and what is its status in clinical trials and FDA approval?
There are 3 genetic targets of the small molecule drug Hydrocodone Bitartrate: OPRK1, OPRD1, and OPRM1. Hydrocodone Bitartrate reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%hydrocodone bitartrate%" OR LOWER(tradeNames_string) LIKE "%hydrocod...
[{'UUID': 'DrugGeneTargets_v2_2476', 'drugName': 'Hydrocodone Bitartrate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'OPRK1 (ENSG00000082556), OPRD1 (ENSG00000116329), OPRM1 (ENSG00000112038)', 'yearOfFirstApproval': 1943, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.661
Q59
What is the genetic target of the small molecule drug Propoxyphene, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Propoxyphene is OPRM1. Propoxyphene reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%propoxyphene%" OR LOWER(tradeNames_string) LIKE "%propoxyphene%" OR ...
[{'UUID': 'DrugGeneTargets_v2_1331', 'drugName': 'Propoxyphene', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'OPRM1 (ENSG00000112038)', 'yearOfFirstApproval': 1957, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3834', 'drugName': 'Propoxyphene Hydrochloride', 'd...
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Q59.560
Q59
What is the genetic target of the small molecule drug Oglemilast, and what is its status in clinical trials and FDA approval?
There are 4 genetic targets of the small molecule drug Oglemilast: PDE4A, PDE4D, PDE4B, and PDE4C. Oglemilast reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%oglemilast%" OR LOWER(tradeNames_string) LIKE "%oglemilast%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_2650', 'drugName': 'Oglemilast', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PDE4A (ENSG00000065989), PDE4D (ENSG00000113448), PDE4B (ENSG00000184588), PDE4C (ENSG00000105650)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}]
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Q59.44
Q59
What is the genetic target of the small molecule drug Trilaciclib, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Trilaciclib: CDK6 and CDK4. Trilaciclib reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%trilaciclib%" OR LOWER(tradeNames_string) LIKE "%trilaciclib%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_171', 'drugName': 'Trilaciclib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CDK6 (ENSG00000105810), CDK4 (ENSG00000135446)', 'yearOfFirstApproval': 2021, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_170', 'drugName': 'Trilaciclib...
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Q59.278
Q59
What is the genetic target of the small molecule drug Dantrolene, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Dantrolene: RYR3 and RYR1. Dantrolene reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%dantrolene%" OR LOWER(tradeNames_string) LIKE "%dantrolene%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_4505', 'drugName': 'Dantrolene Sodium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'RYR3 (ENSG00000198838), RYR1 (ENSG00000196218)', 'yearOfFirstApproval': 1974, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4504', 'drugName': 'Dan...
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Q59.1096
Q59
What is the genetic target of the small molecule drug Paxalisib, and what is its status in clinical trials and FDA approval?
There are 8 genetic targets of the small molecule drug Paxalisib: PIK3R1, PIK3CB, PIK3CG, PIK3CA, PIK3R2, PIK3CD, PIK3R5, and PIK3R3. Paxalisib reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%paxalisib%" OR LOWER(tradeNames_string) LIKE "%paxalisib%" OR LOWER(...
[{'UUID': 'DrugGeneTargets_v2_1740', 'drugName': 'Paxalisib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PIK3R1 (ENSG00000145675), PIK3CB (ENSG00000051382), PIK3CG (ENSG00000105851), PIK3CA (ENSG00000121879), PIK3R2 (ENSG00000105647), PIK3CD (ENSG00000171608), PIK3R5 (ENSG00000141506), PIK3R3 (E...
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Q59.104
Q59
What is the genetic target of the small molecule drug Zolpidem, and what is its status in clinical trials and FDA approval?
There are 3 genetic targets of the small molecule drug Zolpidem: GABRA1, GABRG2, and GABRB1. Zolpidem reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%zolpidem%" OR LOWER(tradeNames_string) LIKE "%zolpidem%" OR LOWER(dr...
[{'UUID': 'DrugGeneTargets_v2_4503', 'drugName': 'Zolpidem', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'GABRA1 (ENSG00000022355), GABRG2 (ENSG00000113327), GABRB1 (ENSG00000163288)', 'yearOfFirstApproval': 1992, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_59...
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Q59.856
Q59
What is the genetic target of the protein drug Gonadorelin Hydrochloride, and what is its status in clinical trials and FDA approval?
The genetic target of the protein drug Gonadorelin Hydrochloride is GNRHR. Gonadorelin Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%gonadorelin hydrochloride%" OR LOWER(tradeNames_string) LIKE "%gonad...
[{'UUID': 'DrugGeneTargets_v2_5262', 'drugName': 'Gonadorelin Hydrochloride', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'GNRHR (ENSG00000109163)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.985
Q59
What is the genetic target of the small molecule drug Ertugliflozin, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Ertugliflozin is SLC5A2. Ertugliflozin reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%ertugliflozin%" OR LOWER(tradeNames_string) LIKE "%ertugliflozin%" O...
[{'UUID': 'DrugGeneTargets_v2_3216', 'drugName': 'Ertugliflozin', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC5A2 (ENSG00000140675)', 'yearOfFirstApproval': 2017, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.948
Q59
What is the genetic target of the small molecule drug Azd-4017, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Azd-4017 is HSD11B1. Azd-4017 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%azd-4017%" OR LOWER(tradeNames_string) LIKE "%azd-4017%" OR LOWER(dr...
[{'UUID': 'DrugGeneTargets_v2_3096', 'drugName': 'Azd-4017', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HSD11B1 (ENSG00000117594)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}]
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Q59.110
Q59
What is the genetic target of the small molecule drug Diflunisal, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Diflunisal: PTGS2 and PTGS1. Diflunisal reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%diflunisal%" OR LOWER(tradeNames_string) LIKE "%diflunisal%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_602', 'drugName': 'Diflunisal', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGS2 (ENSG00000073756), PTGS1 (ENSG00000095303)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1296
Q59
What is the genetic target of the small molecule drug Dolasetron Mesylate, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Dolasetron Mesylate is HTR3A. Dolasetron Mesylate reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%dolasetron mesylate%" OR LOWER(tradeNames_string) LIKE "%dolasetron ...
[{'UUID': 'DrugGeneTargets_v2_2936', 'drugName': 'Dolasetron Mesylate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR3A (ENSG00000166736)', 'yearOfFirstApproval': 1997, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.503
Q59
What is the genetic target of the small molecule drug Methantheline, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Methantheline is HRH2. Methantheline reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%methantheline%" OR LOWER(tradeNames_string) LIKE "%methantheline%" O...
[{'UUID': 'DrugGeneTargets_v2_3052', 'drugName': 'Methantheline', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH2 (ENSG00000113749)', 'yearOfFirstApproval': 1951, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3603', 'drugName': 'Methantheline Bromide', 'drugMo...
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Q59.1981
Q59
What is the genetic target of the small molecule drug Naratriptan Hydrochloride, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Naratriptan Hydrochloride: HTR1B and HTR1D. Naratriptan Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%naratriptan hydrochloride%" OR LOWER(tradeNames_string) LIKE "%narat...
[{'UUID': 'DrugGeneTargets_v2_5845', 'drugName': 'Naratriptan Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR1B (ENSG00000135312), HTR1D (ENSG00000179546)', 'yearOfFirstApproval': 1998, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_5846', 'drugN...
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Q59.869
Q59
What is the genetic target of the small molecule drug Cetirizine Hydrochloride, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Cetirizine Hydrochloride is HRH1. Cetirizine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%cetirizine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%cetiri...
[{'UUID': 'DrugGeneTargets_v2_6377', 'drugName': 'Cetirizine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH1 (ENSG00000196639)', 'yearOfFirstApproval': 1995, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_5631', 'drugName': 'Levocetirizine Dihyd...
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Q59.748
Q59
What is the genetic target of the small molecule drug Oxyphenbutazone, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Oxyphenbutazone: PTGS2 and PTGS1. Oxyphenbutazone reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%oxyphenbutazone%" OR LOWER(tradeNames_string) LIKE "%oxyphenbutazone...
[{'UUID': 'DrugGeneTargets_v2_4669', 'drugName': 'Oxyphenbutazone', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGS2 (ENSG00000073756), PTGS1 (ENSG00000095303)', 'yearOfFirstApproval': 1960, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_172', 'drugName': 'Oxyp...
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Q59.1015
Q59
What is the genetic target of the small molecule drug Propylthiouracil, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Propylthiouracil: TPO and DIO1. Propylthiouracil reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%propylthiouracil%" OR LOWER(tradeNames_string) LIKE "%propylthiourac...
[{'UUID': 'DrugGeneTargets_v2_394', 'drugName': 'Propylthiouracil', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TPO (ENSG00000115705), DIO1 (ENSG00000211452)', 'yearOfFirstApproval': 1947, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_395', 'drugName': 'Propylt...
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Q59.1315
Q59
What is the genetic target of the small molecule drug Fluocinonide, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Fluocinonide is NR3C1. Fluocinonide reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%fluocinonide%" OR LOWER(tradeNames_string) LIKE "%fluocinonide%" OR ...
[{'UUID': 'DrugGeneTargets_v2_4918', 'drugName': 'Fluocinonide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'NR3C1 (ENSG00000113580)', 'yearOfFirstApproval': 1971, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1297
Q59
What is the genetic target of the small molecule drug Capmatinib Hydrochloride, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Capmatinib Hydrochloride is MET. Capmatinib Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%capmatinib hydrochloride%" OR LOWER(tradeNames_string) LIKE "%capmat...
[{'UUID': 'DrugGeneTargets_v2_568', 'drugName': 'Capmatinib Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'MET (ENSG00000105976)', 'yearOfFirstApproval': 2020, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.609
Q59
What is the genetic target of the small molecule drug Encainide, and what is its status in clinical trials and FDA approval?
There are 10 genetic targets of the small molecule drug Encainide: SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. Encainide reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%encainide%" OR LOWER(tradeNames_string) LIKE "%encainide%" OR LOWER(...
[{'UUID': 'DrugGeneTargets_v2_4728', 'drugName': 'Encainide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SCN1A (ENSG00000144285), SCN5A (ENSG00000183873), SCN4A (ENSG00000007314), SCN7A (ENSG00000136546), SCN2A (ENSG00000136531), SCN9A (ENSG00000169432), SCN3A (ENSG00000153253), SCN11A (ENSG0000...
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Q59.1362
Q59
What is the genetic target of the small molecule drug Dextroamphetamine Sulfate, and what is its status in clinical trials and FDA approval?
There are 3 genetic targets of the small molecule drug Dextroamphetamine Sulfate: SLC6A2, SLC6A3, and SLC18A2. Dextroamphetamine Sulfate reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%dextroamphetamine sulfate%" OR LOWER(tradeNames_string) LIKE "%dextr...
[{'UUID': 'DrugGeneTargets_v2_1031', 'drugName': 'Dextroamphetamine Sulfate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A2 (ENSG00000103546), SLC6A3 (ENSG00000142319), SLC18A2 (ENSG00000165646)', 'yearOfFirstApproval': 1960, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'Dru...
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Q59.75
Q59
What is the genetic target of the small molecule drug Alclofenac, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Alclofenac is PTGS1. Alclofenac reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%alclofenac%" OR LOWER(tradeNames_string) LIKE "%alclofenac%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_3320', 'drugName': 'Alclofenac', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGS1 (ENSG00000095303)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1082
Q59
What is the genetic target of the small molecule drug Quetiapine Fumarate, and what is its status in clinical trials and FDA approval?
There are 3 genetic targets of the small molecule drug Quetiapine Fumarate: HTR2A, HTR2C, and DRD2. Quetiapine Fumarate reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%quetiapine fumarate%" OR LOWER(tradeNames_string) LIKE "%quetiapine ...
[{'UUID': 'DrugGeneTargets_v2_4441', 'drugName': 'Quetiapine Fumarate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR2A (ENSG00000102468), HTR2C (ENSG00000147246), DRD2 (ENSG00000149295)', 'yearOfFirstApproval': 1997, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTarget...
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Q59.1214
Q59
What is the genetic target of the small molecule drug Budesonide, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Budesonide is NR3C1. Budesonide reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%budesonide%" OR LOWER(tradeNames_string) LIKE "%budesonide%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_3329', 'drugName': 'Budesonide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'NR3C1 (ENSG00000113580)', 'yearOfFirstApproval': 1994, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1167
Q59
What is the genetic target of the small molecule drug Dichlorobenzyl Alcohol, and what is its status in clinical trials and FDA approval?
There are 10 genetic targets of the small molecule drug Dichlorobenzyl Alcohol: SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. Dichlorobenzyl Alcohol reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%dichlorobenzyl alcohol%" OR LOWER(tradeNames_string) LIKE "%dichloro...
[{'UUID': 'DrugGeneTargets_v2_5003', 'drugName': 'Dichlorobenzyl Alcohol', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SCN1A (ENSG00000144285), SCN5A (ENSG00000183873), SCN4A (ENSG00000007314), SCN7A (ENSG00000136546), SCN2A (ENSG00000136531), SCN9A (ENSG00000169432), SCN3A (ENSG00000153253), SCN...
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Q59.625
Q59
What is the genetic target of the antibody drug Budigalimab, and what is its status in clinical trials and FDA approval?
The genetic target of the antibody drug Budigalimab is PDCD1. Budigalimab reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%budigalimab%" OR LOWER(tradeNames_string) LIKE "%budigalimab%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_6333', 'drugName': 'Budigalimab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'PDCD1 (ENSG00000188389)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}]
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Q59.487
Q59
What is the genetic target of the small molecule drug Diltiazem, and what is its status in clinical trials and FDA approval?
There are 4 genetic targets of the small molecule drug Diltiazem: CACNA1C, CACNA1S, CACNA1D, and CACNA1F. Diltiazem reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%diltiazem%" OR LOWER(tradeNames_string) LIKE "%diltiazem%" OR LOWER(...
[{'UUID': 'DrugGeneTargets_v2_927', 'drugName': 'Diltiazem Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CACNA1C (ENSG00000151067), CACNA1S (ENSG00000081248), CACNA1D (ENSG00000157388), CACNA1F (ENSG00000102001)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsAppro...
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Q59.1579
Q59
What is the genetic target of the small molecule drug Gimatecan, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Gimatecan is TOP1. Gimatecan reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%gimatecan%" OR LOWER(tradeNames_string) LIKE "%gimatecan%" OR LOWER(...
[{'UUID': 'DrugGeneTargets_v2_1470', 'drugName': 'Gimatecan', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TOP1 (ENSG00000198900)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}]
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Q59.512
Q59
What is the genetic target of the small molecule drug Benziodarone, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Benziodarone is CALM1. Benziodarone reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%benziodarone%" OR LOWER(tradeNames_string) LIKE "%benziodarone%" OR ...
[{'UUID': 'DrugGeneTargets_v2_1971', 'drugName': 'Benziodarone', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CALM1 (ENSG00000198668)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.740
Q59
What is the genetic target of the small molecule drug Viloxazine Hydrochloride, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Viloxazine Hydrochloride is SLC6A2. Viloxazine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%viloxazine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%viloxa...
[{'UUID': 'DrugGeneTargets_v2_5502', 'drugName': 'Viloxazine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A2 (ENSG00000103546)', 'yearOfFirstApproval': 2021, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.762
Q59
What is the genetic target of the small molecule drug Cinnarizine, and what is its status in clinical trials and FDA approval?
There are 5 genetic targets of the small molecule drug Cinnarizine: HRH1, CACNA1C, CACNA1S, CACNA1D, and CACNA1F. Cinnarizine reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%cinnarizine%" OR LOWER(tradeNames_string) LIKE "%cinnarizine%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_4535', 'drugName': 'Cinnarizine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH1 (ENSG00000196639), CACNA1C (ENSG00000151067), CACNA1S (ENSG00000081248), CACNA1D (ENSG00000157388), CACNA1F (ENSG00000102001)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'd...
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Q59.1990
Q59
What is the genetic target of the small molecule drug Pantoprazole Sodium, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Pantoprazole Sodium: ATP4A and ATP4B. Pantoprazole Sodium reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%pantoprazole sodium%" OR LOWER(tradeNames_string) LIKE "%pantoprazol...
[{'UUID': 'DrugGeneTargets_v2_1903', 'drugName': 'Pantoprazole Sodium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ATP4A (ENSG00000105675), ATP4B (ENSG00000186009)', 'yearOfFirstApproval': 2000, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.784
Q59
What is the genetic target of the small molecule drug Lorlatinib, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Lorlatinib: ALK and EML4. Lorlatinib reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%lorlatinib%" OR LOWER(tradeNames_string) LIKE "%lorlatinib%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_236', 'drugName': 'Lorlatinib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ALK (ENSG00000171094), EML4 (ENSG00000143924)', 'yearOfFirstApproval': 2018, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_237', 'drugName': 'Lorlatinib', ...
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Q59.1763
Q59
What is the genetic target of the small molecule drug Thiothixene, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Thiothixene: DRD2 and HTR2A. Thiothixene reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%thiothixene%" OR LOWER(tradeNames_string) LIKE "%thiothixene%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_2625', 'drugName': 'Thiothixene', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DRD2 (ENSG00000149295), HTR2A (ENSG00000102468)', 'yearOfFirstApproval': 1967, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2624', 'drugName': 'Thiothix...
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Q59.848
Q59
What is the genetic target of the small molecule drug Tarafenacin, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Tarafenacin is CHRM3. Tarafenacin reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%tarafenacin%" OR LOWER(tradeNames_string) LIKE "%tarafenacin%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_2787', 'drugName': 'Tarafenacin', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRM3 (ENSG00000133019)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}]
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Q59.315
Q59
What is the genetic target of the small molecule drug Lamotrigine, and what is its status in clinical trials and FDA approval?
There are 10 genetic targets of the small molecule drug Lamotrigine: SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. Lamotrigine reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%lamotrigine%" OR LOWER(tradeNames_string) LIKE "%lamotrigine%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_5462', 'drugName': 'Lamotrigine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SCN1A (ENSG00000144285), SCN5A (ENSG00000183873), SCN4A (ENSG00000007314), SCN7A (ENSG00000136546), SCN2A (ENSG00000136531), SCN9A (ENSG00000169432), SCN3A (ENSG00000153253), SCN11A (ENSG00...
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Q59.816
Q59
What is the genetic target of the small molecule drug Nefazodone, and what is its status in clinical trials and FDA approval?
There are 4 genetic targets of the small molecule drug Nefazodone: HTR2C, SLC6A4, SLC6A2, and HTR2A. Nefazodone reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%nefazodone%" OR LOWER(tradeNames_string) LIKE "%nefazodone%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_4082', 'drugName': 'Nefazodone', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR2C (ENSG00000147246), SLC6A4 (ENSG00000108576), SLC6A2 (ENSG00000103546), HTR2A (ENSG00000102468)', 'yearOfFirstApproval': 1994, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUI...
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Q59.411
Q59
What is the genetic target of the protein drug Corifollitropin Alfa, and what is its status in clinical trials and FDA approval?
The genetic target of the protein drug Corifollitropin Alfa is FSHR. Corifollitropin Alfa reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%corifollitropin alfa%" OR LOWER(tradeNames_string) LIKE "%corifollit...
[{'UUID': 'DrugGeneTargets_v2_2306', 'drugName': 'Corifollitropin Alfa', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'FSHR (ENSG00000170820)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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