uuid stringlengths 4 8 | template_uuid stringclasses 40
values | question stringlengths 13 193 | answer stringlengths 29 2.2k | benchmark_query stringlengths 133 622 | execution_results stringlengths 2 1.14M | query_type stringclasses 2
values | sql_category stringclasses 26
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Q59.826 | Q59 | What is the genetic target of the small molecule drug Zaleplon, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Zaleplon: GABRA1, GABRG2, and GABRB1. Zaleplon reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%zaleplon%" OR LOWER(tradeNames_string) LIKE "%zaleplon%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_3395', 'drugName': 'Zaleplon', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'GABRA1 (ENSG00000022355), GABRG2 (ENSG00000113327), GABRB1 (ENSG00000163288)', 'yearOfFirstApproval': 1999, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1143 | Q59 | What is the genetic target of the small molecule drug Nalbuphine, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Nalbuphine: OPRK1, OPRD1, and OPRM1. Nalbuphine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%nalbuphine%" OR LOWER(tradeNames_string) LIKE "%nalbuphine%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_1326', 'drugName': 'Nalbuphine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'OPRK1 (ENSG00000082556), OPRD1 (ENSG00000116329), OPRM1 (ENSG00000112038)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1991',... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.313 | Q59 | What is the genetic target of the small molecule drug Methylprednisolone Sodium Succinate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Methylprednisolone Sodium Succinate is NR3C1. Methylprednisolone Sodium Succinate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%methylprednisolone sodium succinate%" OR LOWER(tradeNames_string) LI... | [{'UUID': 'DrugGeneTargets_v2_5705', 'drugName': 'Methylprednisolone Sodium Succinate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'NR3C1 (ENSG00000113580)', 'yearOfFirstApproval': 1959, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.229 | Q59 | What is the genetic target of the small molecule drug Brensocatib, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Brensocatib is CTSC. Brensocatib reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%brensocatib%" OR LOWER(tradeNames_string) LIKE "%brensocatib%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_1902', 'drugName': 'Brensocatib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CTSC (ENSG00000109861)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1699 | Q59 | What is the genetic target of the protein drug Filgrastim, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Filgrastim is CSF3R. Filgrastim reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%filgrastim%" OR LOWER(tradeNames_string) LIKE "%filgrastim%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_4822', 'drugName': 'Lipegfilgrastim', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'CSF3R (ENSG00000119535)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_5318', 'drugName': 'Filgrastim', 'drugMolecularType': 'Pro... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1451 | Q59 | What is the genetic target of the small molecule drug Xl-418, and what is its status in clinical trials and FDA approval? | There are 5 genetic targets of the small molecule drug Xl-418: AKT2, AKT3, AKT1, RPS6KB2, and RPS6KB1. Xl-418 reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%xl-418%" OR LOWER(tradeNames_string) LIKE "%xl-418%" OR LOWER(drugSy... | [{'UUID': 'DrugGeneTargets_v2_2168', 'drugName': 'Xl-418', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'AKT2 (ENSG00000105221), AKT3 (ENSG00000117020), AKT1 (ENSG00000142208), RPS6KB2 (ENSG00000175634), RPS6KB1 (ENSG00000108443)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApprov... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1976 | Q59 | What is the genetic target of the small molecule drug Molibresib, and what is its status in clinical trials and FDA approval? | There are 4 genetic targets of the small molecule drug Molibresib: BRD2, BRD4, BRDT, and BRD3. Molibresib reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%molibresib%" OR LOWER(tradeNames_string) LIKE "%molibresib%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_6242', 'drugName': 'Molibresib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'BRD2 (ENSG00000204256), BRD4 (ENSG00000141867), BRDT (ENSG00000137948), BRD3 (ENSG00000169925)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.814 | Q59 | What is the genetic target of the protein drug Octreotide Acetate, and what is its status in clinical trials and FDA approval? | There are 5 genetic targets of the protein drug Octreotide Acetate: SSTR5, SSTR2, SSTR4, SSTR1, and SSTR3. Octreotide Acetate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%octreotide acetate%" OR LOWER(tradeNames_string) LIKE "%octreotide a... | [{'UUID': 'DrugGeneTargets_v2_759', 'drugName': 'Octreotide Acetate', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'SSTR5 (ENSG00000162009), SSTR2 (ENSG00000180616), SSTR4 (ENSG00000132671), SSTR1 (ENSG00000139874), SSTR3 (ENSG00000278195)', 'yearOfFirstApproval': 1988, 'maxClinicalTrialPhase': 4, 'drugIs... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1847 | Q59 | What is the genetic target of the small molecule drug Merethoxylline Procaine, and what is its status in clinical trials and FDA approval? | There are 10 genetic targets of the small molecule drug Merethoxylline Procaine: SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. Merethoxylline Procaine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%merethoxylline procaine%" OR LOWER(tradeNames_string) LIKE "%meretho... | [{'UUID': 'DrugGeneTargets_v2_3148', 'drugName': 'Merethoxylline Procaine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SCN1A (ENSG00000144285), SCN5A (ENSG00000183873), SCN4A (ENSG00000007314), SCN7A (ENSG00000136546), SCN2A (ENSG00000136531), SCN9A (ENSG00000169432), SCN3A (ENSG00000153253), SC... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.151 | Q59 | What is the genetic target of the small molecule drug Milvexian, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Milvexian is F11. Milvexian reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%milvexian%" OR LOWER(tradeNames_string) LIKE "%milvexian%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_6387', 'drugName': 'Milvexian', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'F11 (ENSG00000088926)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.781 | Q59 | What is the genetic target of the small molecule drug Armodafinil, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Armodafinil is SLC6A3. Armodafinil reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%armodafinil%" OR LOWER(tradeNames_string) LIKE "%armodafinil%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_2926', 'drugName': 'Armodafinil', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A3 (ENSG00000142319)', 'yearOfFirstApproval': 2007, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.727 | Q59 | What is the genetic target of the small molecule drug Danthron, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Danthron is RXRA. Danthron reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%danthron%" OR LOWER(tradeNames_string) LIKE "%danthron%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_2100', 'drugName': 'Danthron', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'RXRA (ENSG00000186350)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.820 | Q59 | What is the genetic target of the small molecule drug Selumetinib Sulfate, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Selumetinib Sulfate: MAP2K2 and MAP2K1. Selumetinib Sulfate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%selumetinib sulfate%" OR LOWER(tradeNames_string) LIKE "%selumetinib... | [{'UUID': 'DrugGeneTargets_v2_3990', 'drugName': 'Selumetinib Sulfate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'MAP2K2 (ENSG00000126934), MAP2K1 (ENSG00000169032)', 'yearOfFirstApproval': 2020, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1636 | Q59 | What is the genetic target of the small molecule drug Eplerenone, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Eplerenone is NR3C2. Eplerenone reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%eplerenone%" OR LOWER(tradeNames_string) LIKE "%eplerenone%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_4937', 'drugName': 'Eplerenone', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'NR3C2 (ENSG00000151623)', 'yearOfFirstApproval': 2002, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.825 | Q59 | What is the genetic target of the protein drug Mecasermin, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Mecasermin is IGF1R. Mecasermin reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%mecasermin%" OR LOWER(tradeNames_string) LIKE "%mecasermin%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_672', 'drugName': 'Mecasermin Rinfabate', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'IGF1R (ENSG00000140443)', 'yearOfFirstApproval': 2005, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2750', 'drugName': 'Mecasermin', 'drugMolecularType... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.581 | Q59 | What is the genetic target of the small molecule drug Tirofiban, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Tirofiban: ITGB3 and ITGA2B. Tirofiban reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tirofiban%" OR LOWER(tradeNames_string) LIKE "%tirofiban%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_2127', 'drugName': 'Tirofiban', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ITGB3 (ENSG00000259207), ITGA2B (ENSG00000005961)', 'yearOfFirstApproval': 1998, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2897', 'drugName': 'Tirofiba... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.563 | Q59 | What is the genetic target of the antibody drug Alirocumab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Alirocumab is PCSK9. Alirocumab reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%alirocumab%" OR LOWER(tradeNames_string) LIKE "%alirocumab%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_1637', 'drugName': 'Alirocumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'PCSK9 (ENSG00000169174)', 'yearOfFirstApproval': 2015, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1758 | Q59 | What is the genetic target of the small molecule drug Celiprolol, and what is its status in clinical trials and FDA approval? | There are 5 genetic targets of the small molecule drug Celiprolol: ADRB1, ADRA2A, ADRA2C, ADRA2B, and ADRB2. Celiprolol reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%celiprolol%" OR LOWER(tradeNames_string) LIKE "%celiprolol%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_6117', 'drugName': 'Celiprolol', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRB1 (ENSG00000043591), ADRA2A (ENSG00000150594), ADRA2C (ENSG00000184160), ADRA2B (ENSG00000274286), ADRB2 (ENSG00000169252)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIs... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1727 | Q59 | What is the genetic target of the small molecule drug Chlorpheniramine Polistirex, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Chlorpheniramine Polistirex is HRH1. Chlorpheniramine Polistirex reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%chlorpheniramine polistirex%" OR LOWER(tradeNames_string) LIKE "%chl... | [{'UUID': 'DrugGeneTargets_v2_706', 'drugName': 'Chlorpheniramine Polistirex', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH1 (ENSG00000196639)', 'yearOfFirstApproval': 1984, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1349 | Q59 | What is the genetic target of the small molecule drug Amlodipine Maleate, and what is its status in clinical trials and FDA approval? | There are 4 genetic targets of the small molecule drug Amlodipine Maleate: CACNA1C, CACNA1S, CACNA1D, and CACNA1F. Amlodipine Maleate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%amlodipine maleate%" OR LOWER(tradeNames_string) LIKE "%amlodipine m... | [{'UUID': 'DrugGeneTargets_v2_352', 'drugName': 'Amlodipine Maleate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CACNA1C (ENSG00000151067), CACNA1S (ENSG00000081248), CACNA1D (ENSG00000157388), CACNA1F (ENSG00000102001)', 'yearOfFirstApproval': 2003, 'maxClinicalTrialPhase': 4, 'drugIsApproved':... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1161 | Q59 | What is the genetic target of the small molecule drug Bay-1125976, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Bay-1125976: AKT1 and AKT2. Bay-1125976 reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%bay-1125976%" OR LOWER(tradeNames_string) LIKE "%bay-1125976%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_481', 'drugName': 'Bay-1125976', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'AKT1 (ENSG00000142208), AKT2 (ENSG00000105221)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_482', 'drugName': 'Bay-1125976',... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.945 | Q59 | What is the genetic target of the small molecule drug Mifamurtide, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Mifamurtide is NOD2. Mifamurtide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%mifamurtide%" OR LOWER(tradeNames_string) LIKE "%mifamurtide%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_1449', 'drugName': 'Mifamurtide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'NOD2 (ENSG00000167207)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4474', 'drugName': 'Mifamurtide', 'drugMolecularType': '... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.290 | Q59 | What is the genetic target of the small molecule drug Ephedrine Sulfate, and what is its status in clinical trials and FDA approval? | There are 9 genetic targets of the small molecule drug Ephedrine Sulfate: ADRA1A, ADRA2A, ADRB1, ADRB2, ADRA2C, ADRA1D, ADRA1B, ADRA2B, and ADRB3. Ephedrine Sulfate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ephedrine sulfate%" OR LOWER(tradeNames_string) LIKE "%ephedrine sul... | [{'UUID': 'DrugGeneTargets_v2_1353', 'drugName': 'Pseudoephedrine Sulfate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A2 (ENSG00000103546)', 'yearOfFirstApproval': 1963, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4865', 'drugName': 'Ephedrine Sulfate',... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1947 | Q59 | What is the genetic target of the small molecule drug Fispemifene, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Fispemifene: ESR2 and ESR1. Fispemifene reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%fispemifene%" OR LOWER(tradeNames_string) LIKE "%fispemifene%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_2079', 'drugName': 'Fispemifene', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ESR2 (ENSG00000140009), ESR1 (ENSG00000091831)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.973 | Q59 | What is the genetic target of the small molecule drug Perampanel, and what is its status in clinical trials and FDA approval? | There are 4 genetic targets of the small molecule drug Perampanel: GRIA4, GRIA3, GRIA2, and GRIA1. Perampanel reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%perampanel%" OR LOWER(tradeNames_string) LIKE "%perampanel%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_2165', 'drugName': 'Perampanel', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'GRIA4 (ENSG00000152578), GRIA3 (ENSG00000125675), GRIA2 (ENSG00000120251), GRIA1 (ENSG00000155511)', 'yearOfFirstApproval': 2012, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.605 | Q59 | What is the genetic target of the small molecule drug Betamethasone Valerate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Betamethasone Valerate is NR3C1. Betamethasone Valerate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%betamethasone valerate%" OR LOWER(tradeNames_string) LIKE "%betameth... | [{'UUID': 'DrugGeneTargets_v2_5710', 'drugName': 'Betamethasone Valerate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'NR3C1 (ENSG00000113580)', 'yearOfFirstApproval': 1967, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1312 | Q59 | What is the genetic target of the small molecule drug Cenisertib, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Cenisertib: AURKB, AURKC, and AURKA. Cenisertib reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%cenisertib%" OR LOWER(tradeNames_string) LIKE "%cenisertib%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_1559', 'drugName': 'Cenisertib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'AURKB (ENSG00000178999), AURKC (ENSG00000105146), AURKA (ENSG00000087586)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1244 | Q59 | What is the genetic target of the small molecule drug Alverine, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Alverine: HTR1A and HNF4A. Alverine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%alverine%" OR LOWER(tradeNames_string) LIKE "%alverine%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_4846', 'drugName': 'Alverine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR1A (ENSG00000178394), HNF4A (ENSG00000101076)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4847', 'drugName': 'Alverine', 'd... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1638 | Q59 | What is the genetic target of the small molecule drug Cerivastatin, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Cerivastatin is HMGCR. Cerivastatin reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%cerivastatin%" OR LOWER(tradeNames_string) LIKE "%cerivastatin%" OR ... | [{'UUID': 'DrugGeneTargets_v2_877', 'drugName': 'Cerivastatin', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HMGCR (ENSG00000113161)', 'yearOfFirstApproval': 1997, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3117', 'drugName': 'Cerivastatin Sodium', 'drugMolec... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1588 | Q59 | What is the genetic target of the small molecule drug Meclizine, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Meclizine is HRH1. Meclizine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%meclizine%" OR LOWER(tradeNames_string) LIKE "%meclizine%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_5400', 'drugName': 'Meclizine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH1 (ENSG00000196639)', 'yearOfFirstApproval': 1957, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_5753', 'drugName': 'Meclizine', 'drugMole... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1316 | Q59 | What is the genetic target of the small molecule drug Candesartan Cilexetil, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Candesartan Cilexetil is AGTR1. Candesartan Cilexetil reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%candesartan cilexetil%" OR LOWER(tradeNames_string) LIKE "%candesart... | [{'UUID': 'DrugGeneTargets_v2_2579', 'drugName': 'Candesartan Cilexetil', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'AGTR1 (ENSG00000144891)', 'yearOfFirstApproval': 1998, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3868', 'drugName': 'Candesartan', 'drugMol... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1779 | Q59 | What is the genetic target of the small molecule drug Mk-0773, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Mk-0773 is AR. Mk-0773 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%mk-0773%" OR LOWER(tradeNames_string) LIKE "%mk-0773%" OR LOWER(drug... | [{'UUID': 'DrugGeneTargets_v2_3617', 'drugName': 'Mk-0773', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'AR (ENSG00000169083)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1647 | Q59 | What is the genetic target of the small molecule drug Loxapine Succinate, and what is its status in clinical trials and FDA approval? | There are 5 genetic targets of the small molecule drug Loxapine Succinate: HTR2C, HTR2A, DRD2, DRD3, and DRD4. Loxapine Succinate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%loxapine succinate%" OR LOWER(tradeNames_string) LIKE "%loxapine suc... | [{'UUID': 'DrugGeneTargets_v2_488', 'drugName': 'Loxapine Succinate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR2C (ENSG00000147246), HTR2A (ENSG00000102468), DRD2 (ENSG00000149295), DRD3 (ENSG00000151577), DRD4 (ENSG00000069696)', 'yearOfFirstApproval': 1975, 'maxClinicalTrialPhase': 4, 'dr... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1255 | Q59 | What is the genetic target of the protein drug Insulin Susp Isophane Purified Beef, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Insulin Susp Isophane Purified Beef is INSR. Insulin Susp Isophane Purified Beef reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%insulin susp isophane purified beef%" OR LOWER(tradeNames_string) LI... | [{'UUID': 'DrugGeneTargets_v2_4804', 'drugName': 'Insulin Susp Isophane Purified Beef', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'INSR (ENSG00000171105)', 'yearOfFirstApproval': 1980, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1675 | Q59 | What is the genetic target of the antibody drug Epitumomab Cituxetan, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Epitumomab Cituxetan is MUC1. Epitumomab Cituxetan reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%epitumomab cituxetan%" OR LOWER(tradeNames_string) LIKE "%epitumomab... | [{'UUID': 'DrugGeneTargets_v2_781', 'drugName': 'Epitumomab Cituxetan', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'MUC1 (ENSG00000185499)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1801 | Q59 | What is the genetic target of the small molecule drug Tlc-388, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Tlc-388 is TOP1. Tlc-388 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tlc-388%" OR LOWER(tradeNames_string) LIKE "%tlc-388%" OR LOWER(drug... | [{'UUID': 'DrugGeneTargets_v2_1007', 'drugName': 'Tlc-388', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TOP1 (ENSG00000198900)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.759 | Q59 | What is the genetic target of the small molecule drug Canrenoate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Canrenoate is NR3C2. Canrenoate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%canrenoate%" OR LOWER(tradeNames_string) LIKE "%canrenoate%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_82', 'drugName': 'Canrenoate Potassium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'NR3C2 (ENSG00000151623)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4944', 'drugName': 'Canrenoate', 'drugMolecularT... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.616 | Q59 | What is the genetic target of the small molecule drug Iptacopan, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Iptacopan is CFB. Iptacopan reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%iptacopan%" OR LOWER(tradeNames_string) LIKE "%iptacopan%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_3164', 'drugName': 'Iptacopan', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CFB (ENSG00000243649)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1045 | Q59 | What is the genetic target of the antibody drug Siltuximab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Siltuximab is IL6. Siltuximab reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%siltuximab%" OR LOWER(tradeNames_string) LIKE "%siltuximab%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_2074', 'drugName': 'Siltuximab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'IL6 (ENSG00000136244)', 'yearOfFirstApproval': 2014, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.788 | Q59 | What is the genetic target of the small molecule drug Filgotinib, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Filgotinib is JAK1. Filgotinib reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%filgotinib%" OR LOWER(tradeNames_string) LIKE "%filgotinib%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_3779', 'drugName': 'Filgotinib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'JAK1 (ENSG00000162434)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1690 | Q59 | What is the genetic target of the small molecule drug Osi-7904, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Osi-7904 is TYMS. Osi-7904 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%osi-7904%" OR LOWER(tradeNames_string) LIKE "%osi-7904%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_5813', 'drugName': 'Osi-7904', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TYMS (ENSG00000176890)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.997 | Q59 | What is the genetic target of the oligosaccharide drug Idraparinux, and what is its status in clinical trials and FDA approval? | The genetic target of the oligosaccharide drug Idraparinux is F10. Idraparinux reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%idraparinux%" OR LOWER(tradeNames_string) LIKE "%idraparinux%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_938', 'drugName': 'Idraparinux', 'drugMolecularType': 'Oligosaccharide', 'newLinkedTargets_string': 'F10 (ENSG00000126218)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_6379', 'drugName': 'Idraparinux Sodium', 'drugMolecularT... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.499 | Q59 | What is the genetic target of the small molecule drug Incb-9471, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Incb-9471 is CCR5. Incb-9471 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%incb-9471%" OR LOWER(tradeNames_string) LIKE "%incb-9471%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_738', 'drugName': 'Incb-9471', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CCR5 (ENSG00000160791)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1320 | Q59 | What is the genetic target of the antibody drug Gemtuzumab Ozogamicin, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Gemtuzumab Ozogamicin is CD33. Gemtuzumab Ozogamicin reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%gemtuzumab ozogamicin%" OR LOWER(tradeNames_string) LIKE "%gemtuzuma... | [{'UUID': 'DrugGeneTargets_v2_6112', 'drugName': 'Gemtuzumab Ozogamicin', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'CD33 (ENSG00000105383)', 'yearOfFirstApproval': 2000, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.281 | Q59 | What is the genetic target of the small molecule drug Trazpiroben, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Trazpiroben: DRD3 and DRD2. Trazpiroben reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%trazpiroben%" OR LOWER(tradeNames_string) LIKE "%trazpiroben%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_2839', 'drugName': 'Trazpiroben', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DRD3 (ENSG00000151577), DRD2 (ENSG00000149295)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_2840', 'drugName': 'Trazpiroben... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1848 | Q59 | What is the genetic target of the small molecule drug Methacholine, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Methacholine is CHRM3. Methacholine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%methacholine%" OR LOWER(tradeNames_string) LIKE "%methacholine%" OR ... | [{'UUID': 'DrugGeneTargets_v2_4350', 'drugName': 'Methacholine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRM3 (ENSG00000133019)', 'yearOfFirstApproval': 1986, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4509', 'drugName': 'Methacholine Chloride', 'drugMo... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.363 | Q59 | What is the genetic target of the small molecule drug Ziprasidone Mesylate, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Ziprasidone Mesylate: HTR2A, DRD2, and HTR2C. Ziprasidone Mesylate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ziprasidone mesylate%" OR LOWER(tradeNames_string) LIKE "%ziprasidon... | [{'UUID': 'DrugGeneTargets_v2_4286', 'drugName': 'Ziprasidone Mesylate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR2A (ENSG00000102468), DRD2 (ENSG00000149295), HTR2C (ENSG00000147246)', 'yearOfFirstApproval': 2002, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTarge... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1179 | Q59 | What is the genetic target of the small molecule drug Tenapanor, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Tenapanor is SLC9A3. Tenapanor reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tenapanor%" OR LOWER(tradeNames_string) LIKE "%tenapanor%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_4791', 'drugName': 'Tenapanor', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC9A3 (ENSG00000066230)', 'yearOfFirstApproval': 2019, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3816', 'drugName': 'Tenapanor Hydrochloride', 'drugMo... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.239 | Q59 | What is the genetic target of the small molecule drug Oxprenolol, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Oxprenolol: ADRB1 and ADRB2. Oxprenolol reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%oxprenolol%" OR LOWER(tradeNames_string) LIKE "%oxprenolol%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_3598', 'drugName': 'Oxprenolol', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRB1 (ENSG00000043591), ADRB2 (ENSG00000169252)', 'yearOfFirstApproval': 1983, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3597', 'drugName': 'Oxprenol... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.557 | Q59 | What is the genetic target of the antibody drug Humax-Il8, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Humax-Il8 is CXCL8. Humax-Il8 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%humax-il8%" OR LOWER(tradeNames_string) LIKE "%humax-il8%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_4247', 'drugName': 'Humax-Il8', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'CXCL8 (ENSG00000169429)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1870 | Q59 | What is the genetic target of the small molecule drug Citalopram, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Citalopram is SLC6A4. Citalopram reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%citalopram%" OR LOWER(tradeNames_string) LIKE "%citalopram%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_1197', 'drugName': 'Citalopram Hydrobromide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A4 (ENSG00000108576)', 'yearOfFirstApproval': 1998, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_5074', 'drugName': 'Citalopram', 'drugM... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1915 | Q59 | What is the genetic target of the small molecule drug Ly-2090314, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Ly-2090314: GSK3B and GSK3A. Ly-2090314 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ly-2090314%" OR LOWER(tradeNames_string) LIKE "%ly-2090314%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_2361', 'drugName': 'Ly-2090314', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'GSK3B (ENSG00000082701), GSK3A (ENSG00000105723)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_2362', 'drugName': 'Ly-2090314... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.211 | Q59 | What is the genetic target of the antibody drug Eldelumab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Eldelumab is CXCL10. Eldelumab reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%eldelumab%" OR LOWER(tradeNames_string) LIKE "%eldelumab%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_850', 'drugName': 'Eldelumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'CXCL10 (ENSG00000169245)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1922 | Q59 | What is the genetic target of the protein drug Ganirelix Acetate, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Ganirelix Acetate is GNRHR. Ganirelix Acetate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ganirelix acetate%" OR LOWER(tradeNames_string) LIKE "%ganirelix ace... | [{'UUID': 'DrugGeneTargets_v2_113', 'drugName': 'Ganirelix Acetate', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'GNRHR (ENSG00000109163)', 'yearOfFirstApproval': 1999, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1561 | Q59 | What is the genetic target of the oligosaccharide drug Ardeparin Sodium, and what is its status in clinical trials and FDA approval? | The genetic target of the oligosaccharide drug Ardeparin Sodium is SERPINC1. Ardeparin Sodium reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ardeparin sodium%" OR LOWER(tradeNames_string) LIKE "%ardeparin sodi... | [{'UUID': 'DrugGeneTargets_v2_2927', 'drugName': 'Ardeparin Sodium', 'drugMolecularType': 'Oligosaccharide', 'newLinkedTargets_string': 'SERPINC1 (ENSG00000117601)', 'yearOfFirstApproval': 1997, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.60 | Q59 | What is the genetic target of the small molecule drug Temsirolimus, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Temsirolimus is FKBP1A. Temsirolimus reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%temsirolimus%" OR LOWER(tradeNames_string) LIKE "%temsirolimus%" OR ... | [{'UUID': 'DrugGeneTargets_v2_5750', 'drugName': 'Temsirolimus', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'FKBP1A (ENSG00000088832)', 'yearOfFirstApproval': 2007, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1835 | Q59 | What is the genetic target of the antibody drug Mepolizumab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Mepolizumab is IL5. Mepolizumab reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%mepolizumab%" OR LOWER(tradeNames_string) LIKE "%mepolizumab%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_1703', 'drugName': 'Mepolizumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'IL5 (ENSG00000113525)', 'yearOfFirstApproval': 2015, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1906 | Q59 | What is the genetic target of the small molecule drug Linifanib, and what is its status in clinical trials and FDA approval? | There are 7 genetic targets of the small molecule drug Linifanib: FLT3, PDGFRB, PDGFRA, CSF1R, FLT1, FLT4, and KDR. Linifanib reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%linifanib%" OR LOWER(tradeNames_string) LIKE "%linifanib%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_1027', 'drugName': 'Linifanib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'FLT3 (ENSG00000122025), PDGFRB (ENSG00000113721), PDGFRA (ENSG00000134853), CSF1R (ENSG00000182578), FLT1 (ENSG00000102755), FLT4 (ENSG00000037280), KDR (ENSG00000128052)', 'yearOfFirstApprov... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1578 | Q59 | What is the genetic target of the small molecule drug Abivertinib Maleate, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Abivertinib Maleate: BTK and EGFR. Abivertinib Maleate reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%abivertinib maleate%" OR LOWER(tradeNames_string) LIKE "%abivertinib... | [{'UUID': 'DrugGeneTargets_v2_419', 'drugName': 'Abivertinib Maleate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'BTK (ENSG00000010671), EGFR (ENSG00000146648)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_420', 'drugName': 'Abiver... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.368 | Q59 | What is the genetic target of the small molecule drug Buprenorphine Hydrochloride, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Buprenorphine Hydrochloride: OPRM1 and OPRK1. Buprenorphine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%buprenorphine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%bup... | [{'UUID': 'DrugGeneTargets_v2_2028', 'drugName': 'Buprenorphine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'OPRM1 (ENSG00000112038), OPRK1 (ENSG00000082556)', 'yearOfFirstApproval': 1981, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2029', 'dru... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.511 | Q59 | What is the genetic target of the small molecule drug Vilazodone, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Vilazodone: HTR1A and SLC6A4. Vilazodone reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%vilazodone%" OR LOWER(tradeNames_string) LIKE "%vilazodone%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_5197', 'drugName': 'Vilazodone', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR1A (ENSG00000178394), SLC6A4 (ENSG00000108576)', 'yearOfFirstApproval': 2011, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_5196', 'drugName': 'Vilazod... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.815 | Q59 | What is the genetic target of the antibody drug Onartuzumab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Onartuzumab is MET. Onartuzumab reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%onartuzumab%" OR LOWER(tradeNames_string) LIKE "%onartuzumab%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_5019', 'drugName': 'Onartuzumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'MET (ENSG00000105976)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1122 | Q59 | What is the genetic target of the small molecule drug Rosiglitazone, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Rosiglitazone is PPARG. Rosiglitazone reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%rosiglitazone%" OR LOWER(tradeNames_string) LIKE "%rosiglitazone%" O... | [{'UUID': 'DrugGeneTargets_v2_4628', 'drugName': 'Rosiglitazone Maleate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PPARG (ENSG00000132170)', 'yearOfFirstApproval': 1999, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_6144', 'drugName': 'Rosiglitazone', 'drugM... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1731 | Q59 | What is the genetic target of the small molecule drug Bms-777607, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Bms-777607 is MET. Bms-777607 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%bms-777607%" OR LOWER(tradeNames_string) LIKE "%bms-777607%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_5979', 'drugName': 'Bms-777607', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'MET (ENSG00000105976)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1216 | Q59 | What is the genetic target of the small molecule drug Brimonidine, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Brimonidine: ADRA2A, ADRA2C, and ADRA2B. Brimonidine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%brimonidine%" OR LOWER(tradeNames_string) LIKE "%brimonidine%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_4923', 'drugName': 'Brimonidine Tartrate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRA2A (ENSG00000150594), ADRA2C (ENSG00000184160), ADRA2B (ENSG00000274286)', 'yearOfFirstApproval': 1996, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneT... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1212 | Q59 | What is the genetic target of the small molecule drug Pki-166, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Pki-166 is EGFR. Pki-166 reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%pki-166%" OR LOWER(tradeNames_string) LIKE "%pki-166%" OR LOWER(drug... | [{'UUID': 'DrugGeneTargets_v2_5854', 'drugName': 'Pki-166', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'EGFR (ENSG00000146648)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.971 | Q59 | What is the genetic target of the small molecule drug Estradiol Cypionate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Estradiol Cypionate is ESR1. Estradiol Cypionate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%estradiol cypionate%" OR LOWER(tradeNames_string) LIKE "%estradiol c... | [{'UUID': 'DrugGeneTargets_v2_612', 'drugName': 'Estradiol Cypionate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ESR1 (ENSG00000091831)', 'yearOfFirstApproval': 1979, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.805 | Q59 | What is the genetic target of the small molecule drug Sar425899, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Sar425899 is GCGR. Sar425899 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%sar425899%" OR LOWER(tradeNames_string) LIKE "%sar425899%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_5952', 'drugName': 'Sar425899', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'GCGR (ENSG00000215644)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.121 | Q59 | What is the genetic target of the small molecule drug Btrx-335140, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Btrx-335140 is OPRK1. Btrx-335140 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%btrx-335140%" OR LOWER(tradeNames_string) LIKE "%btrx-335140%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_5108', 'drugName': 'Btrx-335140', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'OPRK1 (ENSG00000082556)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1322 | Q59 | What is the genetic target of the small molecule drug Testosterone Propionate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Testosterone Propionate is AR. Testosterone Propionate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%testosterone propionate%" OR LOWER(tradeNames_string) LIKE "%testost... | [{'UUID': 'DrugGeneTargets_v2_2128', 'drugName': 'Testosterone Propionate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'AR (ENSG00000169083)', 'yearOfFirstApproval': 1974, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1221 | Q59 | What is the genetic target of the small molecule drug Pentostatin, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Pentostatin is ADA. Pentostatin reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%pentostatin%" OR LOWER(tradeNames_string) LIKE "%pentostatin%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_251', 'drugName': 'Pentostatin', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADA (ENSG00000196839)', 'yearOfFirstApproval': 1991, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.528 | Q59 | What is the genetic target of the small molecule drug Diflorasone Diacetate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Diflorasone Diacetate is NR3C1. Diflorasone Diacetate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%diflorasone diacetate%" OR LOWER(tradeNames_string) LIKE "%difloraso... | [{'UUID': 'DrugGeneTargets_v2_4747', 'drugName': 'Diflorasone Diacetate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'NR3C1 (ENSG00000113580)', 'yearOfFirstApproval': 1977, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.519 | Q59 | What is the genetic target of the small molecule drug Ono-8539, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Ono-8539 is PTGER1. Ono-8539 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ono-8539%" OR LOWER(tradeNames_string) LIKE "%ono-8539%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_5243', 'drugName': 'Ono-8539', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGER1 (ENSG00000160951)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.84 | Q59 | What is the genetic target of the small molecule drug Pf-00477736, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Pf-00477736 is CHEK1. Pf-00477736 reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%pf-00477736%" OR LOWER(tradeNames_string) LIKE "%pf-00477736%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_5280', 'drugName': 'Pf-00477736', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHEK1 (ENSG00000149554)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.717 | Q59 | What is the genetic target of the antibody drug Etokimab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Etokimab is IL33. Etokimab reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%etokimab%" OR LOWER(tradeNames_string) LIKE "%etokimab%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_2323', 'drugName': 'Etokimab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'IL33 (ENSG00000137033)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1185 | Q59 | What is the genetic target of the small molecule drug Ozanimod Hydrochloride, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Ozanimod Hydrochloride is S1PR1. Ozanimod Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ozanimod hydrochloride%" OR LOWER(tradeNames_string) LIKE "%ozanimod... | [{'UUID': 'DrugGeneTargets_v2_5399', 'drugName': 'Ozanimod Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'S1PR1 (ENSG00000170989)', 'yearOfFirstApproval': 2020, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.386 | Q59 | What is the genetic target of the small molecule drug Ibutilide Fumarate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Ibutilide Fumarate is KCNH2. Ibutilide Fumarate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ibutilide fumarate%" OR LOWER(tradeNames_string) LIKE "%ibutilide fu... | [{'UUID': 'DrugGeneTargets_v2_5277', 'drugName': 'Ibutilide Fumarate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'KCNH2 (ENSG00000055118)', 'yearOfFirstApproval': 1995, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1022 | Q59 | What is the genetic target of the small molecule drug Alcuronium, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Alcuronium is CHRM2. Alcuronium reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%alcuronium%" OR LOWER(tradeNames_string) LIKE "%alcuronium%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_4023', 'drugName': 'Alcuronium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRM2 (ENSG00000181072)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1689 | Q59 | What is the genetic target of the small molecule drug Sibutramine, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Sibutramine: SLC6A4, SLC6A3, and SLC6A2. Sibutramine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%sibutramine%" OR LOWER(tradeNames_string) LIKE "%sibutramine%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_5637', 'drugName': 'Sibutramine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A4 (ENSG00000108576), SLC6A3 (ENSG00000142319), SLC6A2 (ENSG00000103546)', 'yearOfFirstApproval': 1997, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.87 | Q59 | What is the genetic target of the small molecule drug Palomid-529, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Palomid-529 is MTOR. Palomid-529 reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%palomid-529%" OR LOWER(tradeNames_string) LIKE "%palomid-529%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_3689', 'drugName': 'Palomid-529', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'MTOR (ENSG00000198793)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1684 | Q59 | What is the genetic target of the small molecule drug Glpg0492, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Glpg0492 is AR. Glpg0492 reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%glpg0492%" OR LOWER(tradeNames_string) LIKE "%glpg0492%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_1004', 'drugName': 'Glpg0492', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'AR (ENSG00000169083)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.333 | Q59 | What is the genetic target of the antibody drug Abx-Ma1, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Abx-Ma1 is MCAM. Abx-Ma1 reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%abx-ma1%" OR LOWER(tradeNames_string) LIKE "%abx-ma1%" OR LOWER(drug... | [{'UUID': 'DrugGeneTargets_v2_5969', 'drugName': 'Abx-Ma1', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'MCAM (ENSG00000076706)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.7 | Q59 | What is the genetic target of the small molecule drug Phenoxybenzamine, and what is its status in clinical trials and FDA approval? | There are 6 genetic targets of the small molecule drug Phenoxybenzamine: ADRA1A, ADRA2A, ADRA2C, ADRA1D, ADRA1B, and ADRA2B. Phenoxybenzamine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%phenoxybenzamine%" OR LOWER(tradeNames_string) LIKE "%phenoxybenzami... | [{'UUID': 'DrugGeneTargets_v2_5463', 'drugName': 'Phenoxybenzamine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRA1A (ENSG00000120907), ADRA2A (ENSG00000150594), ADRA2C (ENSG00000184160), ADRA1D (ENSG00000171873), ADRA1B (ENSG00000170214), ADRA2B (ENSG00000274286)', 'yearOfFirstApproval': 1953... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.737 | Q59 | What is the genetic target of the small molecule drug Dbpr-108, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Dbpr-108 is DPP4. Dbpr-108 reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%dbpr-108%" OR LOWER(tradeNames_string) LIKE "%dbpr-108%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_2194', 'drugName': 'Dbpr-108', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DPP4 (ENSG00000197635)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.750 | Q59 | What is the genetic target of the small molecule drug Cyclofenil, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Cyclofenil: ESR2 and ESR1. Cyclofenil reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%cyclofenil%" OR LOWER(tradeNames_string) LIKE "%cyclofenil%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_1475', 'drugName': 'Cyclofenil', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ESR2 (ENSG00000140009), ESR1 (ENSG00000091831)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1414 | Q59 | What is the genetic target of the cell drug Amg553, and what is its status in clinical trials and FDA approval? | The genetic target of the cell drug Amg553 is FLT3. Amg553 reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%amg553%" OR LOWER(tradeNames_string) LIKE "%amg553%" OR LOWER(drugSy... | [{'UUID': 'DrugGeneTargets_v2_5110', 'drugName': 'Amg553', 'drugMolecularType': 'Cell', 'newLinkedTargets_string': 'FLT3 (ENSG00000122025)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1751 | Q59 | What is the genetic target of the small molecule drug Duvelisib, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Duvelisib: PIK3CG and PIK3CD. Duvelisib reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%duvelisib%" OR LOWER(tradeNames_string) LIKE "%duvelisib%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_1892', 'drugName': 'Duvelisib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PIK3CG (ENSG00000105851), PIK3CD (ENSG00000171608)', 'yearOfFirstApproval': 2018, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1893', 'drugName': 'Duvelis... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.457 | Q59 | What is the genetic target of the small molecule drug Hydrocortisone Acetate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Hydrocortisone Acetate is NR3C1. Hydrocortisone Acetate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%hydrocortisone acetate%" OR LOWER(tradeNames_string) LIKE "%hydrocor... | [{'UUID': 'DrugGeneTargets_v2_71', 'drugName': 'Hydrocortisone Acetate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'NR3C1 (ENSG00000113580)', 'yearOfFirstApproval': 1951, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1393', 'drugName': 'Fludrocortisone Acetate... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.496 | Q59 | What is the genetic target of the small molecule drug Darifenacin, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Darifenacin: CHRM2 and CHRM3. Darifenacin reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%darifenacin%" OR LOWER(tradeNames_string) LIKE "%darifenacin%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_4015', 'drugName': 'Darifenacin', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRM2 (ENSG00000181072), CHRM3 (ENSG00000133019)', 'yearOfFirstApproval': 2004, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4014', 'drugName': 'Darifen... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1482 | Q59 | What is the genetic target of the small molecule drug Bumetanide, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Bumetanide is SLC12A1. Bumetanide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%bumetanide%" OR LOWER(tradeNames_string) LIKE "%bumetanide%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_2656', 'drugName': 'Bumetanide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC12A1 (ENSG00000074803)', 'yearOfFirstApproval': 1983, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.291 | Q59 | What is the genetic target of the small molecule drug Quinidine Gluconate, and what is its status in clinical trials and FDA approval? | There are 10 genetic targets of the small molecule drug Quinidine Gluconate: SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. Quinidine Gluconate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%quinidine gluconate%" OR LOWER(tradeNames_string) LIKE "%quinidine g... | [{'UUID': 'DrugGeneTargets_v2_2256', 'drugName': 'Quinidine Gluconate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SCN1A (ENSG00000144285), SCN5A (ENSG00000183873), SCN4A (ENSG00000007314), SCN7A (ENSG00000136546), SCN2A (ENSG00000136531), SCN9A (ENSG00000169432), SCN3A (ENSG00000153253), SCN11A... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1817 | Q59 | What is the genetic target of the small molecule drug Petesicatib, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Petesicatib is CTSS. Petesicatib reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%petesicatib%" OR LOWER(tradeNames_string) LIKE "%petesicatib%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_1222', 'drugName': 'Petesicatib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CTSS (ENSG00000163131)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1986 | Q59 | What is the genetic target of the small molecule drug Balsalazide Disodium, and what is its status in clinical trials and FDA approval? | There are 4 genetic targets of the small molecule drug Balsalazide Disodium: PPARG, PTGS2, PTGS1, and ALOX5. Balsalazide Disodium reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%balsalazide disodium%" OR LOWER(tradeNames_string) LIKE "%balsalazid... | [{'UUID': 'DrugGeneTargets_v2_1296', 'drugName': 'Balsalazide Disodium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PPARG (ENSG00000132170), PTGS2 (ENSG00000073756), PTGS1 (ENSG00000095303), ALOX5 (ENSG00000012779)', 'yearOfFirstApproval': 2000, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1370 | Q59 | What is the genetic target of the small molecule drug Migalastat, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Migalastat is GLA. Migalastat reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%migalastat%" OR LOWER(tradeNames_string) LIKE "%migalastat%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_3147', 'drugName': 'Migalastat', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'GLA (ENSG00000102393)', 'yearOfFirstApproval': 2018, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_549', 'drugName': 'Migalastat Hydrochloride', 'drugMole... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.893 | Q59 | What is the genetic target of the antibody drug Daratumumab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Daratumumab is CD38. Daratumumab reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%daratumumab%" OR LOWER(tradeNames_string) LIKE "%daratumumab%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_4167', 'drugName': 'Daratumumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'CD38 (ENSG00000004468)', 'yearOfFirstApproval': 2015, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1063 | Q59 | What is the genetic target of the antibody drug Obinutuzumab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Obinutuzumab is MS4A1. Obinutuzumab reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%obinutuzumab%" OR LOWER(tradeNames_string) LIKE "%obinutuzumab%" OR ... | [{'UUID': 'DrugGeneTargets_v2_847', 'drugName': 'Obinutuzumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'MS4A1 (ENSG00000156738)', 'yearOfFirstApproval': 2013, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1846 | Q59 | What is the genetic target of the small molecule drug Neostigmine Methylsulfate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Neostigmine Methylsulfate is ACHE. Neostigmine Methylsulfate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%neostigmine methylsulfate%" OR LOWER(tradeNames_string) LIKE "%neost... | [{'UUID': 'DrugGeneTargets_v2_1766', 'drugName': 'Neostigmine Methylsulfate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ACHE (ENSG00000087085)', 'yearOfFirstApproval': 2013, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1982 | Q59 | What is the genetic target of the small molecule drug Adomeglivant, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Adomeglivant is GCGR. Adomeglivant reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%adomeglivant%" OR LOWER(tradeNames_string) LIKE "%adomeglivant%" OR ... | [{'UUID': 'DrugGeneTargets_v2_6357', 'drugName': 'Adomeglivant', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'GCGR (ENSG00000215644)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.789 | Q59 | What is the genetic target of the small molecule drug Dienestrol, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Dienestrol is ESR1. Dienestrol reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%dienestrol%" OR LOWER(tradeNames_string) LIKE "%dienestrol%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_5260', 'drugName': 'Dienestrol', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ESR1 (ENSG00000091831)', 'yearOfFirstApproval': 1947, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.866 | Q59 | What is the genetic target of the small molecule drug Naloxone, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Naloxone: OPRK1, OPRD1, and OPRM1. Naloxone reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%naloxone%" OR LOWER(tradeNames_string) LIKE "%naloxone%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_3927', 'drugName': 'Naloxone Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'OPRK1 (ENSG00000082556), OPRD1 (ENSG00000116329), OPRM1 (ENSG00000112038)', 'yearOfFirstApproval': 1971, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTa... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
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