uuid stringlengths 4 8 | template_uuid stringclasses 40
values | question stringlengths 13 193 | answer stringlengths 29 2.2k | benchmark_query stringlengths 133 622 | execution_results stringlengths 2 1.14M | query_type stringclasses 2
values | sql_category stringclasses 26
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Q59.1306 | Q59 | What is the genetic target of the small molecule drug Mk-0249, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Mk-0249 is HRH3. Mk-0249 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%mk-0249%" OR LOWER(tradeNames_string) LIKE "%mk-0249%" OR LOWER(drug... | [{'UUID': 'DrugGeneTargets_v2_2447', 'drugName': 'Mk-0249', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH3 (ENSG00000101180)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1088 | Q59 | What is the genetic target of the small molecule drug Valbenazine, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Valbenazine is SLC18A2. Valbenazine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%valbenazine%" OR LOWER(tradeNames_string) LIKE "%valbenazine%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_4522', 'drugName': 'Valbenazine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC18A2 (ENSG00000165646)', 'yearOfFirstApproval': 2017, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_5423', 'drugName': 'Valbenazine Tosylate', 'drugMo... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1889 | Q59 | What is the genetic target of the small molecule drug Trospium, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Trospium: CHRM3 and CHRM2. Trospium reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%trospium%" OR LOWER(tradeNames_string) LIKE "%trospium%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_6081', 'drugName': 'Trospium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRM3 (ENSG00000133019), CHRM2 (ENSG00000181072)', 'yearOfFirstApproval': 2004, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_6080', 'drugName': 'Trospium',... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.331 | Q59 | What is the genetic target of the antibody drug Efalizumab, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the antibody drug Efalizumab: ITGAL and ITGB2. Efalizumab reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%efalizumab%" OR LOWER(tradeNames_string) LIKE "%efalizumab%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_5558', 'drugName': 'Efalizumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'ITGAL (ENSG00000005844), ITGB2 (ENSG00000160255)', 'yearOfFirstApproval': 2003, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.448 | Q59 | What is the genetic target of the antibody drug Crizanlizumab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Crizanlizumab is SELP. Crizanlizumab reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%crizanlizumab%" OR LOWER(tradeNames_string) LIKE "%crizanlizumab%" O... | [{'UUID': 'DrugGeneTargets_v2_4256', 'drugName': 'Crizanlizumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'SELP (ENSG00000174175)', 'yearOfFirstApproval': 2019, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.766 | Q59 | What is the genetic target of the small molecule drug Caffeine, Citrated, and what is its status in clinical trials and FDA approval? | There are 4 genetic targets of the small molecule drug Caffeine, Citrated: ADORA1, ADORA2B, ADORA3, and ADORA2A. Caffeine, Citrated reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%caffeine, citrated%" OR LOWER(tradeNames_string) LIKE "%caffeine, ci... | [{'UUID': 'DrugGeneTargets_v2_6075', 'drugName': 'Caffeine, Citrated', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADORA1 (ENSG00000163485), ADORA2B (ENSG00000170425), ADORA3 (ENSG00000282608), ADORA2A (ENSG00000128271)', 'yearOfFirstApproval': 1999, 'maxClinicalTrialPhase': 4, 'drugIsApproved': ... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1844 | Q59 | What is the genetic target of the small molecule drug Diclofenac, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Diclofenac: PTGS2 and PTGS1. Diclofenac reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%diclofenac%" OR LOWER(tradeNames_string) LIKE "%diclofenac%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_3087', 'drugName': 'Diclofenac Epolamine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGS2 (ENSG00000073756), PTGS1 (ENSG00000095303)', 'yearOfFirstApproval': 2007, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2818', 'drugName':... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.913 | Q59 | What is the genetic target of the small molecule drug Olanzapine, and what is its status in clinical trials and FDA approval? | There are 5 genetic targets of the small molecule drug Olanzapine: DRD2, DRD3, DRD4, HTR2C, and HTR2A. Olanzapine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%olanzapine%" OR LOWER(tradeNames_string) LIKE "%olanzapine%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_1531', 'drugName': 'Olanzapine Pamoate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR2C (ENSG00000147246), HTR2A (ENSG00000102468), DRD2 (ENSG00000149295), DRD3 (ENSG00000151577), DRD4 (ENSG00000069696)', 'yearOfFirstApproval': 2009, 'maxClinicalTrialPhase': 4, 'd... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1141 | Q59 | What is the genetic target of the small molecule drug Exatecan, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Exatecan is TOP1. Exatecan reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%exatecan%" OR LOWER(tradeNames_string) LIKE "%exatecan%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_2342', 'drugName': 'Exatecan', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TOP1 (ENSG00000198900)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.180 | Q59 | What is the genetic target of the small molecule drug Azd-8055, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Azd-8055 is MTOR. Azd-8055 reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%azd-8055%" OR LOWER(tradeNames_string) LIKE "%azd-8055%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_5914', 'drugName': 'Azd-8055', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'MTOR (ENSG00000198793)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.729 | Q59 | What is the genetic target of the small molecule drug Capsaicin, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Capsaicin is TRPV1. Capsaicin reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%capsaicin%" OR LOWER(tradeNames_string) LIKE "%capsaicin%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_686', 'drugName': 'Capsaicin', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TRPV1 (ENSG00000196689)', 'yearOfFirstApproval': 2009, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_366', 'drugName': 'Zucapsaicin', 'drugMolecularType': '... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1273 | Q59 | What is the genetic target of the small molecule drug Metaproterenol Sulfate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Metaproterenol Sulfate is ADRB2. Metaproterenol Sulfate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%metaproterenol sulfate%" OR LOWER(tradeNames_string) LIKE "%metaprot... | [{'UUID': 'DrugGeneTargets_v2_5266', 'drugName': 'Metaproterenol Sulfate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRB2 (ENSG00000169252)', 'yearOfFirstApproval': 1973, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.89 | Q59 | What is the genetic target of the small molecule drug Thioridazine Hydrochloride, and what is its status in clinical trials and FDA approval? | There are 5 genetic targets of the small molecule drug Thioridazine Hydrochloride: HTR2C, HTR2A, DRD2, DRD3, and DRD4. Thioridazine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%thioridazine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%thio... | [{'UUID': 'DrugGeneTargets_v2_6304', 'drugName': 'Thioridazine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR2C (ENSG00000147246), HTR2A (ENSG00000102468), DRD2 (ENSG00000149295), DRD3 (ENSG00000151577), DRD4 (ENSG00000069696)', 'yearOfFirstApproval': 1962, 'maxClinicalTrialPhase... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1410 | Q59 | What is the genetic target of the small molecule drug Valsartan, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Valsartan is AGTR1. Valsartan reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%valsartan%" OR LOWER(tradeNames_string) LIKE "%valsartan%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_4486', 'drugName': 'Valsartan', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'AGTR1 (ENSG00000144891)', 'yearOfFirstApproval': 1996, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1900 | Q59 | What is the genetic target of the small molecule drug Brivaracetam, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Brivaracetam is SV2A. Brivaracetam reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%brivaracetam%" OR LOWER(tradeNames_string) LIKE "%brivaracetam%" OR ... | [{'UUID': 'DrugGeneTargets_v2_4908', 'drugName': 'Brivaracetam', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SV2A (ENSG00000159164)', 'yearOfFirstApproval': 2016, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.463 | Q59 | What is the genetic target of the small molecule drug Naratriptan, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Naratriptan: HTR1B and HTR1D. Naratriptan reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%naratriptan%" OR LOWER(tradeNames_string) LIKE "%naratriptan%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_4634', 'drugName': 'Naratriptan', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR1B (ENSG00000135312), HTR1D (ENSG00000179546)', 'yearOfFirstApproval': 1998, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4633', 'drugName': 'Naratri... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1830 | Q59 | What is the genetic target of the small molecule drug Nms-1116354, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Nms-1116354 is CDC7. Nms-1116354 reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%nms-1116354%" OR LOWER(tradeNames_string) LIKE "%nms-1116354%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_3994', 'drugName': 'Nms-1116354', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CDC7 (ENSG00000097046)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.55 | Q59 | What is the genetic target of the protein drug Denileukin Diftitox, and what is its status in clinical trials and FDA approval? | There are 4 genetic targets of the protein drug Denileukin Diftitox: IL2RA, IL2RG, IL2RB, and EEF2. Denileukin Diftitox reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%denileukin diftitox%" OR LOWER(tradeNames_string) LIKE "%denileukin ... | [{'UUID': 'DrugGeneTargets_v2_5633', 'drugName': 'Denileukin Diftitox', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'IL2RA (ENSG00000134460), IL2RG (ENSG00000147168), IL2RB (ENSG00000100385), EEF2 (ENSG00000167658)', 'yearOfFirstApproval': 1999, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1503 | Q59 | What is the genetic target of the antibody drug Depemokimab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Depemokimab is IL5. Depemokimab reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%depemokimab%" OR LOWER(tradeNames_string) LIKE "%depemokimab%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_2185', 'drugName': 'Depemokimab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'IL5 (ENSG00000113525)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.650 | Q59 | What is the genetic target of the protein drug Difelikefalin, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Difelikefalin is OPRK1. Difelikefalin reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%difelikefalin%" OR LOWER(tradeNames_string) LIKE "%difelikefalin%" O... | [{'UUID': 'DrugGeneTargets_v2_4408', 'drugName': 'Difelikefalin', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'OPRK1 (ENSG00000082556)', 'yearOfFirstApproval': 2021, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.684 | Q59 | What is the genetic target of the small molecule drug Krp203, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Krp203 is S1PR1. Krp203 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%krp203%" OR LOWER(tradeNames_string) LIKE "%krp203%" OR LOWER(drugSy... | [{'UUID': 'DrugGeneTargets_v2_2799', 'drugName': 'Krp203', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'S1PR1 (ENSG00000170989)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.224 | Q59 | What is the genetic target of the small molecule drug Clemastine Fumarate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Clemastine Fumarate is HRH1. Clemastine Fumarate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%clemastine fumarate%" OR LOWER(tradeNames_string) LIKE "%clemastine ... | [{'UUID': 'DrugGeneTargets_v2_1580', 'drugName': 'Clemastine Fumarate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH1 (ENSG00000196639)', 'yearOfFirstApproval': 1977, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.116 | Q59 | What is the genetic target of the small molecule drug Doxacurium Chloride, and what is its status in clinical trials and FDA approval? | There are 5 genetic targets of the small molecule drug Doxacurium Chloride: CHRNA1, CHRNG, CHRNB1, CHRND, and CHRNE. Doxacurium Chloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%doxacurium chloride%" OR LOWER(tradeNames_string) LIKE "%doxacurium ... | [{'UUID': 'DrugGeneTargets_v2_5531', 'drugName': 'Doxacurium Chloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRNA1 (ENSG00000138435), CHRNG (ENSG00000196811), CHRNB1 (ENSG00000170175), CHRND (ENSG00000135902), CHRNE (ENSG00000108556)', 'yearOfFirstApproval': 1991, 'maxClinicalTrialPhase':... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1552 | Q59 | What is the genetic target of the small molecule drug Norethynodrel, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Norethynodrel is PGR. Norethynodrel reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%norethynodrel%" OR LOWER(tradeNames_string) LIKE "%norethynodrel%" O... | [{'UUID': 'DrugGeneTargets_v2_1815', 'drugName': 'Norethynodrel', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PGR (ENSG00000082175)', 'yearOfFirstApproval': 1961, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1303 | Q59 | What is the genetic target of the small molecule drug Fenoprofen, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Fenoprofen: PTGS2 and PTGS1. Fenoprofen reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%fenoprofen%" OR LOWER(tradeNames_string) LIKE "%fenoprofen%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_4670', 'drugName': 'Fenoprofen', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGS2 (ENSG00000073756), PTGS1 (ENSG00000095303)', 'yearOfFirstApproval': 1976, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3093', 'drugName': 'Fenoprof... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.987 | Q59 | What is the genetic target of the small molecule drug Levalbuterol Hydrochloride, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Levalbuterol Hydrochloride is ADRB2. Levalbuterol Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%levalbuterol hydrochloride%" OR LOWER(tradeNames_string) LIKE "%leva... | [{'UUID': 'DrugGeneTargets_v2_1198', 'drugName': 'Levalbuterol Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRB2 (ENSG00000169252)', 'yearOfFirstApproval': 1999, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.177 | Q59 | What is the genetic target of the antibody drug Daclizumab, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the antibody drug Daclizumab: IL2RA, IL2RG, and IL2RB. Daclizumab reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%daclizumab%" OR LOWER(tradeNames_string) LIKE "%daclizumab%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_5681', 'drugName': 'Daclizumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'IL2RA (ENSG00000134460), IL2RG (ENSG00000147168), IL2RB (ENSG00000100385)', 'yearOfFirstApproval': 1997, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1650 | Q59 | What is the genetic target of the small molecule drug Lorcaserin Hydrochloride, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Lorcaserin Hydrochloride is HTR2C. Lorcaserin Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%lorcaserin hydrochloride%" OR LOWER(tradeNames_string) LIKE "%lorcas... | [{'UUID': 'DrugGeneTargets_v2_4924', 'drugName': 'Lorcaserin Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR2C (ENSG00000147246)', 'yearOfFirstApproval': 2012, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.596 | Q59 | What is the genetic target of the small molecule drug Carphenazine Maleate, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Carphenazine Maleate: HTR2C, DRD2, and HTR2A. Carphenazine Maleate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%carphenazine maleate%" OR LOWER(tradeNames_string) LIKE "%carphenazi... | [{'UUID': 'DrugGeneTargets_v2_3158', 'drugName': 'Carphenazine Maleate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR2C (ENSG00000147246), DRD2 (ENSG00000149295), HTR2A (ENSG00000102468)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTarge... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1560 | Q59 | What is the genetic target of the small molecule drug Clemastine, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Clemastine is HRH1. Clemastine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%clemastine%" OR LOWER(tradeNames_string) LIKE "%clemastine%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_1580', 'drugName': 'Clemastine Fumarate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH1 (ENSG00000196639)', 'yearOfFirstApproval': 1977, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_6183', 'drugName': 'Clemastine', 'drugMolecul... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.19 | Q59 | What is the genetic target of the small molecule drug Pradigastat, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Pradigastat is DGAT1. Pradigastat reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%pradigastat%" OR LOWER(tradeNames_string) LIKE "%pradigastat%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_3433', 'drugName': 'Pradigastat', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DGAT1 (ENSG00000185000)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.429 | Q59 | What is the genetic target of the small molecule drug Benzphetamine Hydrochloride, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Benzphetamine Hydrochloride: SLC6A2 and SLC18A2. Benzphetamine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%benzphetamine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%ben... | [{'UUID': 'DrugGeneTargets_v2_167', 'drugName': 'Benzphetamine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A2 (ENSG00000103546), SLC18A2 (ENSG00000165646)', 'yearOfFirstApproval': 1960, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_168', 'dr... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1345 | Q59 | What is the genetic target of the small molecule drug Isoetharine, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Isoetharine is ADRB2. Isoetharine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%isoetharine%" OR LOWER(tradeNames_string) LIKE "%isoetharine%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_3508', 'drugName': 'Isoetharine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRB2 (ENSG00000169252)', 'yearOfFirstApproval': 1979, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2925', 'drugName': 'Isoetharine Hydrochloride', 'dru... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.289 | Q59 | What is the genetic target of the small molecule drug Imipramine Pamoate, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Imipramine Pamoate: SLC6A4 and SLC6A2. Imipramine Pamoate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%imipramine pamoate%" OR LOWER(tradeNames_string) LIKE "%imipramine p... | [{'UUID': 'DrugGeneTargets_v2_654', 'drugName': 'Imipramine Pamoate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A4 (ENSG00000108576), SLC6A2 (ENSG00000103546)', 'yearOfFirstApproval': 1973, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_655', 'drugName': '... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1584 | Q59 | What is the genetic target of the small molecule drug Escitalopram, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Escitalopram is SLC6A4. Escitalopram reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%escitalopram%" OR LOWER(tradeNames_string) LIKE "%escitalopram%" OR ... | [{'UUID': 'DrugGeneTargets_v2_4125', 'drugName': 'Escitalopram Oxalate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A4 (ENSG00000108576)', 'yearOfFirstApproval': 2002, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_767', 'drugName': 'Escitalopram', 'drugMol... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.434 | Q59 | What is the genetic target of the small molecule drug Zonisamide, and what is its status in clinical trials and FDA approval? | There are 10 genetic targets of the small molecule drug Zonisamide: SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. Zonisamide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%zonisamide%" OR LOWER(tradeNames_string) LIKE "%zonisamide%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_315', 'drugName': 'Zonisamide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SCN1A (ENSG00000144285), SCN5A (ENSG00000183873), SCN4A (ENSG00000007314), SCN7A (ENSG00000136546), SCN2A (ENSG00000136531), SCN9A (ENSG00000169432), SCN3A (ENSG00000153253), SCN11A (ENSG0000... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1640 | Q59 | What is the genetic target of the small molecule drug Pf-03654746, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Pf-03654746 is HRH3. Pf-03654746 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%pf-03654746%" OR LOWER(tradeNames_string) LIKE "%pf-03654746%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_443', 'drugName': 'Pf-03654746', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH3 (ENSG00000101180)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1245 | Q59 | What is the genetic target of the small molecule drug Trimethadione, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Trimethadione: CACNA1H, CACNA1G, and CACNA1I. Trimethadione reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%trimethadione%" OR LOWER(tradeNames_string) LIKE "%trimethadione%" O... | [{'UUID': 'DrugGeneTargets_v2_4418', 'drugName': 'Trimethadione', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CACNA1H (ENSG00000196557), CACNA1G (ENSG00000006283), CACNA1I (ENSG00000100346)', 'yearOfFirstApproval': 1946, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.676 | Q59 | What is the genetic target of the small molecule drug Tropicamide, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Tropicamide is CHRM3. Tropicamide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tropicamide%" OR LOWER(tradeNames_string) LIKE "%tropicamide%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_1110', 'drugName': 'Tropicamide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRM3 (ENSG00000133019)', 'yearOfFirstApproval': 1960, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.32 | Q59 | What is the genetic target of the small molecule drug Ipratropium Bromide, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Ipratropium Bromide is CHRM3. Ipratropium Bromide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ipratropium bromide%" OR LOWER(tradeNames_string) LIKE "%ipratropium... | [{'UUID': 'DrugGeneTargets_v2_4927', 'drugName': 'Ipratropium Bromide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRM3 (ENSG00000133019)', 'yearOfFirstApproval': 1986, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.934 | Q59 | What is the genetic target of the small molecule drug Caficrestat, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Caficrestat is AKR1B1. Caficrestat reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%caficrestat%" OR LOWER(tradeNames_string) LIKE "%caficrestat%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_6263', 'drugName': 'Caficrestat', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'AKR1B1 (ENSG00000085662)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.982 | Q59 | What is the genetic target of the antibody drug Nivolumab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Nivolumab is PDCD1. Nivolumab reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%nivolumab%" OR LOWER(tradeNames_string) LIKE "%nivolumab%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_1668', 'drugName': 'Nivolumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'PDCD1 (ENSG00000188389)', 'yearOfFirstApproval': 2015, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.217 | Q59 | What is the genetic target of the small molecule drug Buprenorphine, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Buprenorphine: OPRM1 and OPRK1. Buprenorphine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%buprenorphine%" OR LOWER(tradeNames_string) LIKE "%buprenorphine%" O... | [{'UUID': 'DrugGeneTargets_v2_3501', 'drugName': 'Buprenorphine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'OPRM1 (ENSG00000112038), OPRK1 (ENSG00000082556)', 'yearOfFirstApproval': 1981, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3500', 'drugName': 'Bupre... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1130 | Q59 | What is the genetic target of the small molecule drug Cilazapril, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Cilazapril is ACE. Cilazapril reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%cilazapril%" OR LOWER(tradeNames_string) LIKE "%cilazapril%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_3862', 'drugName': 'Cilazapril', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ACE (ENSG00000159640)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.330 | Q59 | What is the genetic target of the small molecule drug Brinzolamide, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Brinzolamide is CA2. Brinzolamide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%brinzolamide%" OR LOWER(tradeNames_string) LIKE "%brinzolamide%" OR ... | [{'UUID': 'DrugGeneTargets_v2_3430', 'drugName': 'Brinzolamide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CA2 (ENSG00000104267)', 'yearOfFirstApproval': 1998, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.566 | Q59 | What is the genetic target of the small molecule drug Desipramine, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Desipramine is SLC6A2. Desipramine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%desipramine%" OR LOWER(tradeNames_string) LIKE "%desipramine%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_1435', 'drugName': 'Desipramine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A2 (ENSG00000103546)', 'yearOfFirstApproval': 1964, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3926', 'drugName': 'Desipramine Hydrochloride', 'dr... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1112 | Q59 | What is the genetic target of the small molecule drug Dextroamphetamine Adipate, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Dextroamphetamine Adipate: SLC18A2, SLC6A2, and SLC6A3. Dextroamphetamine Adipate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%dextroamphetamine adipate%" OR LOWER(tradeNames_string) LIKE "%dextr... | [{'UUID': 'DrugGeneTargets_v2_3241', 'drugName': 'Dextroamphetamine Adipate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC18A2 (ENSG00000165646), SLC6A2 (ENSG00000103546), SLC6A3 (ENSG00000142319)', 'yearOfFirstApproval': 1975, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'Dru... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.707 | Q59 | What is the genetic target of the small molecule drug Fenoprofen Calcium, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Fenoprofen Calcium: PTGS2 and PTGS1. Fenoprofen Calcium reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%fenoprofen calcium%" OR LOWER(tradeNames_string) LIKE "%fenoprofen c... | [{'UUID': 'DrugGeneTargets_v2_3093', 'drugName': 'Fenoprofen Calcium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGS2 (ENSG00000073756), PTGS1 (ENSG00000095303)', 'yearOfFirstApproval': 1976, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1979 | Q59 | What is the genetic target of the small molecule drug Idarubicin Hydrochloride, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Idarubicin Hydrochloride is TOP2A. Idarubicin Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%idarubicin hydrochloride%" OR LOWER(tradeNames_string) LIKE "%idarub... | [{'UUID': 'DrugGeneTargets_v2_5440', 'drugName': 'Idarubicin Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TOP2A (ENSG00000131747)', 'yearOfFirstApproval': 1990, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1189 | Q59 | What is the genetic target of the antibody drug Teneliximab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Teneliximab is CD40. Teneliximab reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%teneliximab%" OR LOWER(tradeNames_string) LIKE "%teneliximab%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_5569', 'drugName': 'Teneliximab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'CD40 (ENSG00000101017)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.345 | Q59 | What is the genetic target of the small molecule drug Rocuronium Bromide, and what is its status in clinical trials and FDA approval? | There are 5 genetic targets of the small molecule drug Rocuronium Bromide: CHRNA1, CHRNG, CHRNB1, CHRND, and CHRNE. Rocuronium Bromide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%rocuronium bromide%" OR LOWER(tradeNames_string) LIKE "%rocuronium b... | [{'UUID': 'DrugGeneTargets_v2_3086', 'drugName': 'Rocuronium Bromide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRNA1 (ENSG00000138435), CHRNG (ENSG00000196811), CHRNB1 (ENSG00000170175), CHRND (ENSG00000135902), CHRNE (ENSG00000108556)', 'yearOfFirstApproval': 1994, 'maxClinicalTrialPhase': ... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.636 | Q59 | What is the genetic target of the small molecule drug Clopidogrel, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Clopidogrel is P2RY12. Clopidogrel reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%clopidogrel%" OR LOWER(tradeNames_string) LIKE "%clopidogrel%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_5437', 'drugName': 'Clopidogrel Bisulfate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'P2RY12 (ENSG00000169313)', 'yearOfFirstApproval': 1997, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_6029', 'drugName': 'Clopidogrel', 'drugMo... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.150 | Q59 | What is the genetic target of the small molecule drug Perphenazine, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Perphenazine is DRD2. Perphenazine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%perphenazine%" OR LOWER(tradeNames_string) LIKE "%perphenazine%" OR ... | [{'UUID': 'DrugGeneTargets_v2_202', 'drugName': 'Perphenazine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DRD2 (ENSG00000149295)', 'yearOfFirstApproval': 1957, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1197 | Q59 | What is the genetic target of the small molecule drug Metocurine Iodide, and what is its status in clinical trials and FDA approval? | There are 5 genetic targets of the small molecule drug Metocurine Iodide: CHRNA1, CHRNG, CHRNB1, CHRND, and CHRNE. Metocurine Iodide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%metocurine iodide%" OR LOWER(tradeNames_string) LIKE "%metocurine io... | [{'UUID': 'DrugGeneTargets_v2_2699', 'drugName': 'Metocurine Iodide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRNA1 (ENSG00000138435), CHRNG (ENSG00000196811), CHRNB1 (ENSG00000170175), CHRND (ENSG00000135902), CHRNE (ENSG00000108556)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.365 | Q59 | What is the genetic target of the small molecule drug Difluprednate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Difluprednate is NR3C1. Difluprednate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%difluprednate%" OR LOWER(tradeNames_string) LIKE "%difluprednate%" O... | [{'UUID': 'DrugGeneTargets_v2_207', 'drugName': 'Difluprednate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'NR3C1 (ENSG00000113580)', 'yearOfFirstApproval': 2008, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.86 | Q59 | What is the genetic target of the small molecule drug Meperidine Hydrochloride, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Meperidine Hydrochloride is OPRM1. Meperidine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%meperidine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%meperi... | [{'UUID': 'DrugGeneTargets_v2_497', 'drugName': 'Meperidine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'OPRM1 (ENSG00000112038)', 'yearOfFirstApproval': 1942, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.49 | Q59 | What is the genetic target of the small molecule drug Isoxicam, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Isoxicam: PTGS2 and PTGS1. Isoxicam reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%isoxicam%" OR LOWER(tradeNames_string) LIKE "%isoxicam%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_1802', 'drugName': 'Isoxicam', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGS2 (ENSG00000073756), PTGS1 (ENSG00000095303)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.474 | Q59 | What is the genetic target of the small molecule drug Carbachol, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Carbachol is CHRM3. Carbachol reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%carbachol%" OR LOWER(tradeNames_string) LIKE "%carbachol%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_990', 'drugName': 'Carbachol', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRM3 (ENSG00000133019)', 'yearOfFirstApproval': 1972, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4597', 'drugName': 'Carbachol', 'drugMolecularType': 'S... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.158 | Q59 | What is the genetic target of the antibody drug Cobolimab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Cobolimab is HAVCR2. Cobolimab reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%cobolimab%" OR LOWER(tradeNames_string) LIKE "%cobolimab%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_5425', 'drugName': 'Cobolimab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'HAVCR2 (ENSG00000135077)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.764 | Q59 | What is the genetic target of the small molecule drug Edoxaban Tosylate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Edoxaban Tosylate is F10. Edoxaban Tosylate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%edoxaban tosylate%" OR LOWER(tradeNames_string) LIKE "%edoxaban tosy... | [{'UUID': 'DrugGeneTargets_v2_5025', 'drugName': 'Edoxaban Tosylate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'F10 (ENSG00000126218)', 'yearOfFirstApproval': 2015, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1027 | Q59 | What is the genetic target of the antibody drug Ahn-12, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Ahn-12 is PTPRC. Ahn-12 reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ahn-12%" OR LOWER(tradeNames_string) LIKE "%ahn-12%" OR LOWER(drugSy... | [{'UUID': 'DrugGeneTargets_v2_1374', 'drugName': 'Ahn-12', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'PTPRC (ENSG00000081237)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1200 | Q59 | What is the genetic target of the small molecule drug Hydroxychloroquine, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Hydroxychloroquine: TLR7 and TLR9. Hydroxychloroquine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%hydroxychloroquine%" OR LOWER(tradeNames_string) LIKE "%hydroxychlor... | [{'UUID': 'DrugGeneTargets_v2_963', 'drugName': 'Hydroxychloroquine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TLR7 (ENSG00000196664), TLR9 (ENSG00000239732)', 'yearOfFirstApproval': 1955, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_962', 'drugName': 'Hydr... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1404 | Q59 | What is the genetic target of the small molecule drug Rimegepant, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Rimegepant is CALCRL. Rimegepant reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%rimegepant%" OR LOWER(tradeNames_string) LIKE "%rimegepant%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_1056', 'drugName': 'Rimegepant', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CALCRL (ENSG00000064989)', 'yearOfFirstApproval': 2020, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3190', 'drugName': 'Rimegepant Sulfate', 'drugMolecu... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1202 | Q59 | What is the genetic target of the small molecule drug Galantamine, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Galantamine is ACHE. Galantamine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%galantamine%" OR LOWER(tradeNames_string) LIKE "%galantamine%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_1632', 'drugName': 'Galantamine Hydrobromide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ACHE (ENSG00000087085)', 'yearOfFirstApproval': 2001, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3143', 'drugName': 'Galantamine', 'drugM... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1631 | Q59 | What is the genetic target of the small molecule drug Benztropine, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Benztropine is CHRM1. Benztropine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%benztropine%" OR LOWER(tradeNames_string) LIKE "%benztropine%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_321', 'drugName': 'Benztropine Mesylate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRM1 (ENSG00000168539)', 'yearOfFirstApproval': 1954, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2039', 'drugName': 'Benztropine', 'drugMolec... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.506 | Q59 | What is the genetic target of the small molecule drug Canertinib Dihydrochloride, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Canertinib Dihydrochloride: EGFR, ERBB2, and ERBB4. Canertinib Dihydrochloride reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%canertinib dihydrochloride%" OR LOWER(tradeNames_string) LIKE "%cane... | [{'UUID': 'DrugGeneTargets_v2_4700', 'drugName': 'Canertinib Dihydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'EGFR (ENSG00000146648), ERBB2 (ENSG00000141736), ERBB4 (ENSG00000178568)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}, {'UUID': 'DrugGeneT... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1670 | Q59 | What is the genetic target of the antibody drug Inclacumab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Inclacumab is SELP. Inclacumab reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%inclacumab%" OR LOWER(tradeNames_string) LIKE "%inclacumab%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_4203', 'drugName': 'Inclacumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'SELP (ENSG00000174175)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.182 | Q59 | What is the genetic target of the small molecule drug Hexocyclium, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Hexocyclium: CHRM1 and CHRM3. Hexocyclium reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%hexocyclium%" OR LOWER(tradeNames_string) LIKE "%hexocyclium%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_3245', 'drugName': 'Hexocyclium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRM1 (ENSG00000168539), CHRM3 (ENSG00000133019)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3244', 'drugName': 'Hexocyc... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1419 | Q59 | What is the genetic target of the small molecule drug Mequinol, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Mequinol is TYR. Mequinol reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%mequinol%" OR LOWER(tradeNames_string) LIKE "%mequinol%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_5010', 'drugName': 'Mequinol', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TYR (ENSG00000077498)', 'yearOfFirstApproval': 1999, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1014 | Q59 | What is the genetic target of the small molecule drug Ruxolitinib Phosphate, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Ruxolitinib Phosphate: JAK1 and JAK2. Ruxolitinib Phosphate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ruxolitinib phosphate%" OR LOWER(tradeNames_string) LIKE "%ruxolitin... | [{'UUID': 'DrugGeneTargets_v2_1727', 'drugName': 'Ruxolitinib Phosphate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'JAK1 (ENSG00000162434), JAK2 (ENSG00000096968)', 'yearOfFirstApproval': 2011, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1728', 'drugName': ... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1978 | Q59 | What is the genetic target of the small molecule drug Pralidoxime Chloride, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Pralidoxime Chloride is ACHE. Pralidoxime Chloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%pralidoxime chloride%" OR LOWER(tradeNames_string) LIKE "%pralidoxim... | [{'UUID': 'DrugGeneTargets_v2_4265', 'drugName': 'Pralidoxime Chloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ACHE (ENSG00000087085)', 'yearOfFirstApproval': 1964, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.864 | Q59 | What is the genetic target of the small molecule drug Adapalene, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Adapalene: RARG, RARB, and RARA. Adapalene reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%adapalene%" OR LOWER(tradeNames_string) LIKE "%adapalene%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_1916', 'drugName': 'Adapalene', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'RARG (ENSG00000172819), RARB (ENSG00000077092), RARA (ENSG00000131759)', 'yearOfFirstApproval': 1996, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1620 | Q59 | What is the genetic target of the small molecule drug Torsemide, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Torsemide is SLC12A1. Torsemide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%torsemide%" OR LOWER(tradeNames_string) LIKE "%torsemide%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_4709', 'drugName': 'Torsemide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC12A1 (ENSG00000074803)', 'yearOfFirstApproval': 1993, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.534 | Q59 | What is the genetic target of the small molecule drug Frovatriptan, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Frovatriptan: HTR1D and HTR1B. Frovatriptan reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%frovatriptan%" OR LOWER(tradeNames_string) LIKE "%frovatriptan%" OR ... | [{'UUID': 'DrugGeneTargets_v2_3513', 'drugName': 'Frovatriptan', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR1D (ENSG00000179546), HTR1B (ENSG00000135312)', 'yearOfFirstApproval': 2001, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3512', 'drugName': 'Frovat... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.350 | Q59 | What is the genetic target of the small molecule drug Phenylbutazone, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Phenylbutazone: PTGS2 and PTGS1. Phenylbutazone reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%phenylbutazone%" OR LOWER(tradeNames_string) LIKE "%phenylbutazone%"... | [{'UUID': 'DrugGeneTargets_v2_4421', 'drugName': 'Phenylbutazone', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGS2 (ENSG00000073756), PTGS1 (ENSG00000095303)', 'yearOfFirstApproval': 1980, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1389 | Q59 | What is the genetic target of the small molecule drug Amp579, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Amp579: ADORA2A and ADORA1. Amp579 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%amp579%" OR LOWER(tradeNames_string) LIKE "%amp579%" OR LOWER(drugSy... | [{'UUID': 'DrugGeneTargets_v2_727', 'drugName': 'Amp579', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADORA2A (ENSG00000128271), ADORA1 (ENSG00000163485)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_728', 'drugName': 'Amp579', 'dru... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1961 | Q59 | What is the genetic target of the small molecule drug Fluvoxamine, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Fluvoxamine is SLC6A4. Fluvoxamine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%fluvoxamine%" OR LOWER(tradeNames_string) LIKE "%fluvoxamine%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_4665', 'drugName': 'Fluvoxamine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A4 (ENSG00000108576)', 'yearOfFirstApproval': 1994, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1759', 'drugName': 'Fluvoxamine Maleate', 'drugMole... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1301 | Q59 | What is the genetic target of the oligonucleotide drug Defibrotide Sodium, and what is its status in clinical trials and FDA approval? | The genetic target of the oligonucleotide drug Defibrotide Sodium is PLG. Defibrotide Sodium reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%defibrotide sodium%" OR LOWER(tradeNames_string) LIKE "%defibrotide ... | [{'UUID': 'DrugGeneTargets_v2_826', 'drugName': 'Defibrotide Sodium', 'drugMolecularType': 'Oligonucleotide', 'newLinkedTargets_string': 'PLG (ENSG00000122194)', 'yearOfFirstApproval': 2016, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1973 | Q59 | What is the genetic target of the small molecule drug Lanatoside C, and what is its status in clinical trials and FDA approval? | There are 8 genetic targets of the small molecule drug Lanatoside C: ATP1A1, ATP1B2, ATP1B1, ATP1A2, ATP1B3, ATP1A3, ATP1A4, and FXYD2. Lanatoside C reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%lanatoside c%" OR LOWER(tradeNames_string) LIKE "%lanatoside c%" OR ... | [{'UUID': 'DrugGeneTargets_v2_2987', 'drugName': 'Lanatoside C', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ATP1A1 (ENSG00000163399), ATP1B2 (ENSG00000129244), ATP1B1 (ENSG00000143153), ATP1A2 (ENSG00000018625), ATP1B3 (ENSG00000069849), ATP1A3 (ENSG00000105409), ATP1A4 (ENSG00000132681), FXYD2 ... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1980 | Q59 | What is the genetic target of the small molecule drug Tak-901, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Tak-901 is AURKB. Tak-901 reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tak-901%" OR LOWER(tradeNames_string) LIKE "%tak-901%" OR LOWER(drug... | [{'UUID': 'DrugGeneTargets_v2_122', 'drugName': 'Tak-901', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'AURKB (ENSG00000178999)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.608 | Q59 | What is the genetic target of the small molecule drug Dexchlorpheniramine Maleate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Dexchlorpheniramine Maleate is HRH1. Dexchlorpheniramine Maleate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%dexchlorpheniramine maleate%" OR LOWER(tradeNames_string) LIKE "%dex... | [{'UUID': 'DrugGeneTargets_v2_6213', 'drugName': 'Dexchlorpheniramine Maleate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH1 (ENSG00000196639)', 'yearOfFirstApproval': 1981, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1050 | Q59 | What is the genetic target of the small molecule drug Codeine Polistirex, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Codeine Polistirex: OPRK1, OPRD1, and OPRM1. Codeine Polistirex reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%codeine polistirex%" OR LOWER(tradeNames_string) LIKE "%codeine poli... | [{'UUID': 'DrugGeneTargets_v2_494', 'drugName': 'Codeine Polistirex', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'OPRK1 (ENSG00000082556), OPRD1 (ENSG00000116329), OPRM1 (ENSG00000112038)', 'yearOfFirstApproval': 1985, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.246 | Q59 | What is the genetic target of the small molecule drug Buclizine Hydrochloride, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Buclizine Hydrochloride is HRH1. Buclizine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%buclizine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%buclizi... | [{'UUID': 'DrugGeneTargets_v2_2564', 'drugName': 'Buclizine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH1 (ENSG00000196639)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1681 | Q59 | What is the genetic target of the small molecule drug Brivanib, and what is its status in clinical trials and FDA approval? | There are 7 genetic targets of the small molecule drug Brivanib: FLT1, FLT4, KDR, FGFR3, FGFR1, FGFR4, and FGFR2. Brivanib reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%brivanib%" OR LOWER(tradeNames_string) LIKE "%brivanib%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_415', 'drugName': 'Brivanib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'FLT1 (ENSG00000102755), FLT4 (ENSG00000037280), KDR (ENSG00000128052), FGFR3 (ENSG00000068078), FGFR1 (ENSG00000077782), FGFR4 (ENSG00000160867), FGFR2 (ENSG00000066468)', 'yearOfFirstApproval'... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1799 | Q59 | What is the genetic target of the protein drug Mecasermin Rinfabate, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Mecasermin Rinfabate is IGF1R. Mecasermin Rinfabate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%mecasermin rinfabate%" OR LOWER(tradeNames_string) LIKE "%mecasermin... | [{'UUID': 'DrugGeneTargets_v2_672', 'drugName': 'Mecasermin Rinfabate', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'IGF1R (ENSG00000140443)', 'yearOfFirstApproval': 2005, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1717 | Q59 | What is the genetic target of the small molecule drug Risedronate Sodium, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Risedronate Sodium is FDPS. Risedronate Sodium reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%risedronate sodium%" OR LOWER(tradeNames_string) LIKE "%risedronate ... | [{'UUID': 'DrugGeneTargets_v2_4717', 'drugName': 'Risedronate Sodium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'FDPS (ENSG00000160752)', 'yearOfFirstApproval': 1998, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.316 | Q59 | What is the genetic target of the small molecule drug Diphenylpyraline, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Diphenylpyraline is HRH1. Diphenylpyraline reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%diphenylpyraline%" OR LOWER(tradeNames_string) LIKE "%diphenylpyrali... | [{'UUID': 'DrugGeneTargets_v2_6116', 'drugName': 'Diphenylpyraline', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH1 (ENSG00000196639)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4165', 'drugName': 'Diphenylpyraline Hydrochlori... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.441 | Q59 | What is the genetic target of the small molecule drug Tazemetostat, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Tazemetostat is EZH2. Tazemetostat reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tazemetostat%" OR LOWER(tradeNames_string) LIKE "%tazemetostat%" OR ... | [{'UUID': 'DrugGeneTargets_v2_1211', 'drugName': 'Tazemetostat', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'EZH2 (ENSG00000106462)', 'yearOfFirstApproval': 2020, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4960', 'drugName': 'Tazemetostat Hydrobromide', 'dru... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1899 | Q59 | What is the genetic target of the small molecule drug Estradiol, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Estradiol is ESR1. Estradiol reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%estradiol%" OR LOWER(tradeNames_string) LIKE "%estradiol%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_4393', 'drugName': 'Estradiol Valerate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ESR1 (ENSG00000091831)', 'yearOfFirstApproval': 2010, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_223', 'drugName': 'Estriol', 'drugMolecularTyp... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1637 | Q59 | What is the genetic target of the small molecule drug Rabeprazole, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Rabeprazole: ATP4A and ATP4B. Rabeprazole reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%rabeprazole%" OR LOWER(tradeNames_string) LIKE "%rabeprazole%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_5144', 'drugName': 'Rabeprazole Sodium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ATP4A (ENSG00000105675), ATP4B (ENSG00000186009)', 'yearOfFirstApproval': 1999, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3572', 'drugName': '... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.312 | Q59 | What is the genetic target of the small molecule drug Radiprodil, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Radiprodil: GRIN1 and GRIN2B. Radiprodil reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%radiprodil%" OR LOWER(tradeNames_string) LIKE "%radiprodil%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_1000', 'drugName': 'Radiprodil', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'GRIN1 (ENSG00000176884), GRIN2B (ENSG00000273079)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.436 | Q59 | What is the genetic target of the antibody drug Ongericimab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Ongericimab is PCSK9. Ongericimab reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ongericimab%" OR LOWER(tradeNames_string) LIKE "%ongericimab%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_3754', 'drugName': 'Ongericimab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'PCSK9 (ENSG00000169174)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.667 | Q59 | What is the genetic target of the antibody drug Golimumab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Golimumab is TNF. Golimumab reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%golimumab%" OR LOWER(tradeNames_string) LIKE "%golimumab%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_393', 'drugName': 'Golimumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'TNF (ENSG00000232810)', 'yearOfFirstApproval': 2009, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.376 | Q59 | What is the genetic target of the small molecule drug Anlotinib, and what is its status in clinical trials and FDA approval? | There are 4 genetic targets of the small molecule drug Anlotinib: FLT4, KIT, PDGFRB, and KDR. Anlotinib reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%anlotinib%" OR LOWER(tradeNames_string) LIKE "%anlotinib%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_1261', 'drugName': 'Anlotinib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'FLT4 (ENSG00000037280), KIT (ENSG00000157404), PDGFRB (ENSG00000113721), KDR (ENSG00000128052)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}, {'UUID': 'Drug... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.572 | Q59 | What is the genetic target of the protein drug Insulin Zinc, Prompt, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Insulin Zinc, Prompt is INSR. Insulin Zinc, Prompt reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%insulin zinc, prompt%" OR LOWER(tradeNames_string) LIKE "%insulin zi... | [{'UUID': 'DrugGeneTargets_v2_3610', 'drugName': 'Insulin Zinc, Prompt', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'INSR (ENSG00000171105)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1226 | Q59 | What is the genetic target of the protein drug Asunercept, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Asunercept is FASLG. Asunercept reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%asunercept%" OR LOWER(tradeNames_string) LIKE "%asunercept%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_1223', 'drugName': 'Asunercept', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'FASLG (ENSG00000117560)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.184 | Q59 | What is the genetic target of the protein drug Abatacept, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the protein drug Abatacept: CD80 and CD86. Abatacept reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%abatacept%" OR LOWER(tradeNames_string) LIKE "%abatacept%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_3638', 'drugName': 'Abatacept', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'CD80 (ENSG00000121594), CD86 (ENSG00000114013)', 'yearOfFirstApproval': 2006, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3639', 'drugName': 'Abatacept', 'drugM... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1115 | Q59 | What is the genetic target of the small molecule drug Tezacaftor, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Tezacaftor is CFTR. Tezacaftor reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tezacaftor%" OR LOWER(tradeNames_string) LIKE "%tezacaftor%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_5304', 'drugName': 'Tezacaftor', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CFTR (ENSG00000001626)', 'yearOfFirstApproval': 2018, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.628 | Q59 | What is the genetic target of the small molecule drug Prednicarbate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Prednicarbate is NR3C1. Prednicarbate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%prednicarbate%" OR LOWER(tradeNames_string) LIKE "%prednicarbate%" O... | [{'UUID': 'DrugGeneTargets_v2_3323', 'drugName': 'Prednicarbate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'NR3C1 (ENSG00000113580)', 'yearOfFirstApproval': 1991, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1910 | Q59 | What is the genetic target of the small molecule drug Prazosin Hydrochloride, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Prazosin Hydrochloride: ADRA1A, ADRA1D, and ADRA1B. Prazosin Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%prazosin hydrochloride%" OR LOWER(tradeNames_string) LIKE "%prazosin... | [{'UUID': 'DrugGeneTargets_v2_5265', 'drugName': 'Prazosin Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRA1A (ENSG00000120907), ADRA1D (ENSG00000171873), ADRA1B (ENSG00000170214)', 'yearOfFirstApproval': 1976, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
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