uuid stringlengths 4 8 | template_uuid stringclasses 40
values | question stringlengths 13 193 | answer stringlengths 29 2.2k | benchmark_query stringlengths 133 622 | execution_results stringlengths 2 1.14M | query_type stringclasses 2
values | sql_category stringclasses 26
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Q59.1192 | Q59 | What is the genetic target of the small molecule drug Hexocyclium Methylsulfate, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Hexocyclium Methylsulfate: CHRM1 and CHRM3. Hexocyclium Methylsulfate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%hexocyclium methylsulfate%" OR LOWER(tradeNames_string) LIKE "%hexoc... | [{'UUID': 'DrugGeneTargets_v2_2265', 'drugName': 'Hexocyclium Methylsulfate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRM1 (ENSG00000168539), CHRM3 (ENSG00000133019)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2266', 'drugN... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.940 | Q59 | What is the genetic target of the protein drug Goserelin, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Goserelin is GNRHR. Goserelin reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%goserelin%" OR LOWER(tradeNames_string) LIKE "%goserelin%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_246', 'drugName': 'Goserelin Acetate', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'GNRHR (ENSG00000109163)', 'yearOfFirstApproval': 1989, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2259', 'drugName': 'Goserelin', 'drugMolecularType': '... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1774 | Q59 | What is the genetic target of the small molecule drug Cedazuridine, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Cedazuridine is CDA. Cedazuridine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%cedazuridine%" OR LOWER(tradeNames_string) LIKE "%cedazuridine%" OR ... | [{'UUID': 'DrugGeneTargets_v2_2765', 'drugName': 'Cedazuridine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CDA (ENSG00000158825)', 'yearOfFirstApproval': 2020, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1842 | Q59 | What is the genetic target of the small molecule drug Guanabenz, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Guanabenz: ADRA2A, ADRA2C, and ADRA2B. Guanabenz reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%guanabenz%" OR LOWER(tradeNames_string) LIKE "%guanabenz%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_2810', 'drugName': 'Guanabenz', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRA2A (ENSG00000150594), ADRA2C (ENSG00000184160), ADRA2B (ENSG00000274286)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1331 | Q59 | What is the genetic target of the oligonucleotide drug Inotersen Sodium, and what is its status in clinical trials and FDA approval? | The genetic target of the oligonucleotide drug Inotersen Sodium is TTR. Inotersen Sodium reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%inotersen sodium%" OR LOWER(tradeNames_string) LIKE "%inotersen sodi... | [{'UUID': 'DrugGeneTargets_v2_3256', 'drugName': 'Inotersen Sodium', 'drugMolecularType': 'Oligonucleotide', 'newLinkedTargets_string': 'TTR (ENSG00000118271)', 'yearOfFirstApproval': 2018, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.300 | Q59 | What is the genetic target of the protein drug Darbepoetin Alfa, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Darbepoetin Alfa is EPOR. Darbepoetin Alfa reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%darbepoetin alfa%" OR LOWER(tradeNames_string) LIKE "%darbepoetin al... | [{'UUID': 'DrugGeneTargets_v2_4490', 'drugName': 'Darbepoetin Alfa', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'EPOR (ENSG00000187266)', 'yearOfFirstApproval': 2001, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1619 | Q59 | What is the genetic target of the small molecule drug Beloranib, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Beloranib is METAP2. Beloranib reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%beloranib%" OR LOWER(tradeNames_string) LIKE "%beloranib%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_2571', 'drugName': 'Beloranib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'METAP2 (ENSG00000111142)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.467 | Q59 | What is the genetic target of the small molecule drug Pioglitazone Hydrochloride, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Pioglitazone Hydrochloride is PPARG. Pioglitazone Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%pioglitazone hydrochloride%" OR LOWER(tradeNames_string) LIKE "%piog... | [{'UUID': 'DrugGeneTargets_v2_878', 'drugName': 'Pioglitazone Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PPARG (ENSG00000132170)', 'yearOfFirstApproval': 1999, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1302 | Q59 | What is the genetic target of the small molecule drug Metaraminol, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Metaraminol: ADRA1A, ADRA1D, and ADRA1B. Metaraminol reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%metaraminol%" OR LOWER(tradeNames_string) LIKE "%metaraminol%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_2338', 'drugName': 'Metaraminol', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRA1A (ENSG00000120907), ADRA1D (ENSG00000171873), ADRA1B (ENSG00000170214)', 'yearOfFirstApproval': 1954, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1250 | Q59 | What is the genetic target of the small molecule drug Rilmenidine, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Rilmenidine is NISCH. Rilmenidine reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%rilmenidine%" OR LOWER(tradeNames_string) LIKE "%rilmenidine%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_3253', 'drugName': 'Rilmenidine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'NISCH (ENSG00000010322)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.383 | Q59 | What is the genetic target of the small molecule drug Conivaptan Hydrochloride, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Conivaptan Hydrochloride: AVPR1A and AVPR2. Conivaptan Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%conivaptan hydrochloride%" OR LOWER(tradeNames_string) LIKE "%coniva... | [{'UUID': 'DrugGeneTargets_v2_3359', 'drugName': 'Conivaptan Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'AVPR1A (ENSG00000166148), AVPR2 (ENSG00000126895)', 'yearOfFirstApproval': 2005, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3360', 'drugN... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1768 | Q59 | What is the genetic target of the small molecule drug Triprolidine Hydrochloride, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Triprolidine Hydrochloride is HRH1. Triprolidine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%triprolidine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%trip... | [{'UUID': 'DrugGeneTargets_v2_2151', 'drugName': 'Triprolidine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH1 (ENSG00000196639)', 'yearOfFirstApproval': 1983, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.108 | Q59 | What is the genetic target of the small molecule drug Betamethasone Acetate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Betamethasone Acetate is NR3C1. Betamethasone Acetate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%betamethasone acetate%" OR LOWER(tradeNames_string) LIKE "%betametha... | [{'UUID': 'DrugGeneTargets_v2_4913', 'drugName': 'Betamethasone Acetate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'NR3C1 (ENSG00000113580)', 'yearOfFirstApproval': 1965, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.129 | Q59 | What is the genetic target of the small molecule drug Hydrocortamate Hydrochloride, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Hydrocortamate Hydrochloride is NR3C1. Hydrocortamate Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%hydrocortamate hydrochloride%" OR LOWER(tradeNames_string) LIKE "%hy... | [{'UUID': 'DrugGeneTargets_v2_5082', 'drugName': 'Hydrocortamate Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'NR3C1 (ENSG00000113580)', 'yearOfFirstApproval': 1956, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1131 | Q59 | What is the genetic target of the small molecule drug Procaine Hydrochloride, and what is its status in clinical trials and FDA approval? | There are 10 genetic targets of the small molecule drug Procaine Hydrochloride: SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. Procaine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%procaine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%procaine... | [{'UUID': 'DrugGeneTargets_v2_2951', 'drugName': 'Procaine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SCN1A (ENSG00000144285), SCN5A (ENSG00000183873), SCN4A (ENSG00000007314), SCN7A (ENSG00000136546), SCN2A (ENSG00000136531), SCN9A (ENSG00000169432), SCN3A (ENSG00000153253), SCN... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.872 | Q59 | What is the genetic target of the small molecule drug Methacholine Chloride, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Methacholine Chloride is CHRM3. Methacholine Chloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%methacholine chloride%" OR LOWER(tradeNames_string) LIKE "%methachol... | [{'UUID': 'DrugGeneTargets_v2_4509', 'drugName': 'Methacholine Chloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRM3 (ENSG00000133019)', 'yearOfFirstApproval': 1986, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.360 | Q59 | What is the genetic target of the small molecule drug Prucalopride Succinate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Prucalopride Succinate is HTR4. Prucalopride Succinate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%prucalopride succinate%" OR LOWER(tradeNames_string) LIKE "%prucalop... | [{'UUID': 'DrugGeneTargets_v2_2465', 'drugName': 'Prucalopride Succinate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR4 (ENSG00000164270)', 'yearOfFirstApproval': 2018, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1617 | Q59 | What is the genetic target of the small molecule drug Burixafor, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Burixafor is CXCR4. Burixafor reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%burixafor%" OR LOWER(tradeNames_string) LIKE "%burixafor%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_6324', 'drugName': 'Burixafor', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CXCR4 (ENSG00000121966)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.689 | Q59 | What is the genetic target of the small molecule drug Methylergonovine Maleate, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Methylergonovine Maleate: DRD1 and HTR2B. Methylergonovine Maleate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%methylergonovine maleate%" OR LOWER(tradeNames_string) LIKE "%methyl... | [{'UUID': 'DrugGeneTargets_v2_2336', 'drugName': 'Methylergonovine Maleate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DRD1 (ENSG00000184845), HTR2B (ENSG00000135914)', 'yearOfFirstApproval': 1946, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2337', 'drugNam... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1787 | Q59 | What is the genetic target of the oligonucleotide drug Vutrisiran, and what is its status in clinical trials and FDA approval? | The genetic target of the oligonucleotide drug Vutrisiran is TTR. Vutrisiran reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%vutrisiran%" OR LOWER(tradeNames_string) LIKE "%vutrisiran%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_2234', 'drugName': 'Vutrisiran', 'drugMolecularType': 'Oligonucleotide', 'newLinkedTargets_string': 'TTR (ENSG00000118271)', 'yearOfFirstApproval': 2022, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1467 | Q59 | What is the genetic target of the small molecule drug Dextromethorphan Hydrobromide, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Dextromethorphan Hydrobromide: GRIN2A and SIGMAR1. Dextromethorphan Hydrobromide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%dextromethorphan hydrobromide%" OR LOWER(tradeNames_string) LIKE "%d... | [{'UUID': 'DrugGeneTargets_v2_5995', 'drugName': 'Dextromethorphan Hydrobromide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'GRIN2A (ENSG00000183454), SIGMAR1 (ENSG00000147955)', 'yearOfFirstApproval': 1984, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_5996',... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.212 | Q59 | What is the genetic target of the antibody drug Necitumumab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Necitumumab is EGFR. Necitumumab reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%necitumumab%" OR LOWER(tradeNames_string) LIKE "%necitumumab%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_2498', 'drugName': 'Necitumumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'EGFR (ENSG00000146648)', 'yearOfFirstApproval': 2015, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.880 | Q59 | What is the genetic target of the small molecule drug Meclofenamic Acid, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Meclofenamic Acid: ALOX5, PTGS2, and PTGS1. Meclofenamic Acid reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%meclofenamic acid%" OR LOWER(tradeNames_string) LIKE "%meclofenamic ... | [{'UUID': 'DrugGeneTargets_v2_3725', 'drugName': 'Meclofenamate Sodium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ALOX5 (ENSG00000012779), PTGS2 (ENSG00000073756), PTGS1 (ENSG00000095303)', 'yearOfFirstApproval': 1980, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTarg... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.143 | Q59 | What is the genetic target of the small molecule drug Asapiprant, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Asapiprant is PTGDR. Asapiprant reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%asapiprant%" OR LOWER(tradeNames_string) LIKE "%asapiprant%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_2227', 'drugName': 'Asapiprant', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGDR (ENSG00000168229)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1439 | Q59 | What is the genetic target of the protein drug Secretin, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Secretin is SCTR. Secretin reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%secretin%" OR LOWER(tradeNames_string) LIKE "%secretin%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_4400', 'drugName': 'Secretin', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'SCTR (ENSG00000080293)', 'yearOfFirstApproval': 2002, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4712', 'drugName': 'Secretin Synthetic Human', 'drugMolecularTy... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1341 | Q59 | What is the genetic target of the small molecule drug Tebanicline Tosylate, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Tebanicline Tosylate: CHRNB2 and CHRNA4. Tebanicline Tosylate reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tebanicline tosylate%" OR LOWER(tradeNames_string) LIKE "%tebaniclin... | [{'UUID': 'DrugGeneTargets_v2_360', 'drugName': 'Tebanicline Tosylate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRNB2 (ENSG00000160716), CHRNA4 (ENSG00000101204)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1786 | Q59 | What is the genetic target of the small molecule drug Ivacaftor, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Ivacaftor is CFTR. Ivacaftor reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ivacaftor%" OR LOWER(tradeNames_string) LIKE "%ivacaftor%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_5639', 'drugName': 'Ivacaftor', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CFTR (ENSG00000001626)', 'yearOfFirstApproval': 2012, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1575 | Q59 | What is the genetic target of the small molecule drug Ribociclib, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Ribociclib: CDK4 and CDK6. Ribociclib reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ribociclib%" OR LOWER(tradeNames_string) LIKE "%ribociclib%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_3488', 'drugName': 'Ribociclib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CDK4 (ENSG00000135446), CDK6 (ENSG00000105810)', 'yearOfFirstApproval': 2017, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3487', 'drugName': 'Ribociclib... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1865 | Q59 | What is the genetic target of the small molecule drug Ebrotidine, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Ebrotidine is HRH2. Ebrotidine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ebrotidine%" OR LOWER(tradeNames_string) LIKE "%ebrotidine%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_4636', 'drugName': 'Ebrotidine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH2 (ENSG00000113749)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4637', 'drugName': 'Ebrotidine', 'drugMolecularType': 'Sm... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1749 | Q59 | What is the genetic target of the small molecule drug Dipyrone, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Dipyrone: PTGS2 and PTGS1. Dipyrone reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%dipyrone%" OR LOWER(tradeNames_string) LIKE "%dipyrone%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_2814', 'drugName': 'Dipyrone', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGS2 (ENSG00000073756), PTGS1 (ENSG00000095303)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4334', 'drugName': 'Dipyrone', 'd... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.718 | Q59 | What is the genetic target of the small molecule drug Ribociclib Succinate, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Ribociclib Succinate: CDK4 and CDK6. Ribociclib Succinate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ribociclib succinate%" OR LOWER(tradeNames_string) LIKE "%ribociclib... | [{'UUID': 'DrugGeneTargets_v2_2092', 'drugName': 'Ribociclib Succinate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CDK4 (ENSG00000135446), CDK6 (ENSG00000105810)', 'yearOfFirstApproval': 2017, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2093', 'drugName': '... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1936 | Q59 | What is the genetic target of the small molecule drug Isoflurophate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Isoflurophate is ACHE. Isoflurophate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%isoflurophate%" OR LOWER(tradeNames_string) LIKE "%isoflurophate%" O... | [{'UUID': 'DrugGeneTargets_v2_1803', 'drugName': 'Isoflurophate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ACHE (ENSG00000087085)', 'yearOfFirstApproval': 1957, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.852 | Q59 | What is the genetic target of the small molecule drug Dihydroergotamine Mesylate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Dihydroergotamine Mesylate is HTR1D. Dihydroergotamine Mesylate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%dihydroergotamine mesylate%" OR LOWER(tradeNames_string) LIKE "%dihy... | [{'UUID': 'DrugGeneTargets_v2_5316', 'drugName': 'Dihydroergotamine Mesylate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR1D (ENSG00000179546)', 'yearOfFirstApproval': 1946, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1938 | Q59 | What is the genetic target of the protein drug Insulin Aspart, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Insulin Aspart is INSR. Insulin Aspart reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%insulin aspart%" OR LOWER(tradeNames_string) LIKE "%insulin aspart%"... | [{'UUID': 'DrugGeneTargets_v2_4979', 'drugName': 'Insulin Aspart', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'INSR (ENSG00000171105)', 'yearOfFirstApproval': 2000, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1048', 'drugName': 'Insulin Aspart Protamine Recombinant'... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.11 | Q59 | What is the genetic target of the enzyme drug Human C1-Esterase Inhibitor, and what is its status in clinical trials and FDA approval? | There are 4 genetic targets of the enzyme drug Human C1-Esterase Inhibitor: C1S, F11, KLKB1, and F12. Human C1-Esterase Inhibitor reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%human c1-esterase inhibitor%" OR LOWER(tradeNames_string) LIKE "%hum... | [{'UUID': 'DrugGeneTargets_v2_2063', 'drugName': 'Human C1-Esterase Inhibitor', 'drugMolecularType': 'Enzyme', 'newLinkedTargets_string': 'C1S (ENSG00000182326), F11 (ENSG00000088926), KLKB1 (ENSG00000164344), F12 (ENSG00000131187)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID'... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1695 | Q59 | What is the genetic target of the small molecule drug Tazarotene, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Tazarotene: RARG, RARB, and RARA. Tazarotene reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tazarotene%" OR LOWER(tradeNames_string) LIKE "%tazarotene%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_5124', 'drugName': 'Tazarotene', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'RARG (ENSG00000172819), RARB (ENSG00000077092), RARA (ENSG00000131759)', 'yearOfFirstApproval': 1997, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1124 | Q59 | What is the genetic target of the small molecule drug Dextroamphetamine, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Dextroamphetamine: SLC6A3, SLC6A2, and SLC18A2. Dextroamphetamine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%dextroamphetamine%" OR LOWER(tradeNames_string) LIKE "%dextroampheta... | [{'UUID': 'DrugGeneTargets_v2_1033', 'drugName': 'Dextroamphetamine Sulfate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A2 (ENSG00000103546), SLC6A3 (ENSG00000142319), SLC18A2 (ENSG00000165646)', 'yearOfFirstApproval': 1960, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'Dru... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.286 | Q59 | What is the genetic target of the small molecule drug Esketamine, and what is its status in clinical trials and FDA approval? | There are 7 genetic targets of the small molecule drug Esketamine: GRIN1, GRIN2A, GRIN2B, GRIN2D, GRIN3B, GRIN2C, and GRIN3A. Esketamine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%esketamine%" OR LOWER(tradeNames_string) LIKE "%esketamine%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_4482', 'drugName': 'Esketamine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'GRIN1 (ENSG00000176884), GRIN2A (ENSG00000183454), GRIN2B (ENSG00000273079), GRIN2D (ENSG00000105464), GRIN3B (ENSG00000116032), GRIN2C (ENSG00000161509), GRIN3A (ENSG00000198785)', 'yearOfF... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.817 | Q59 | What is the genetic target of the small molecule drug Gt-0918, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Gt-0918 is AR. Gt-0918 reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%gt-0918%" OR LOWER(tradeNames_string) LIKE "%gt-0918%" OR LOWER(drug... | [{'UUID': 'DrugGeneTargets_v2_6298', 'drugName': 'Gt-0918', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'AR (ENSG00000169083)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1092 | Q59 | What is the genetic target of the protein drug Choriogonadotropin Alfa, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Choriogonadotropin Alfa is LHCGR. Choriogonadotropin Alfa reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%choriogonadotropin alfa%" OR LOWER(tradeNames_string) LIKE "%choriog... | [{'UUID': 'DrugGeneTargets_v2_1368', 'drugName': 'Choriogonadotropin Alfa', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'LHCGR (ENSG00000138039)', 'yearOfFirstApproval': 2000, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.295 | Q59 | What is the genetic target of the small molecule drug Lapatinib Ditosylate, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Lapatinib Ditosylate: EGFR and ERBB2. Lapatinib Ditosylate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%lapatinib ditosylate%" OR LOWER(tradeNames_string) LIKE "%lapatinib ... | [{'UUID': 'DrugGeneTargets_v2_2160', 'drugName': 'Lapatinib Ditosylate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'EGFR (ENSG00000146648), ERBB2 (ENSG00000141736)', 'yearOfFirstApproval': 2007, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2161', 'drugName': ... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.761 | Q59 | What is the genetic target of the protein drug Albinterferon Alfa-2B, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the protein drug Albinterferon Alfa-2B: IFNAR1 and IFNAR2. Albinterferon Alfa-2B reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%albinterferon alfa-2b%" OR LOWER(tradeNames_string) LIKE "%albinterf... | [{'UUID': 'DrugGeneTargets_v2_6085', 'drugName': 'Albinterferon Alfa-2B', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'IFNAR1 (ENSG00000142166), IFNAR2 (ENSG00000159110)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.633 | Q59 | What is the genetic target of the small molecule drug Desvenlafaxine Succinate, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Desvenlafaxine Succinate: SLC6A4 and SLC6A2. Desvenlafaxine Succinate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%desvenlafaxine succinate%" OR LOWER(tradeNames_string) LIKE "%desven... | [{'UUID': 'DrugGeneTargets_v2_735', 'drugName': 'Desvenlafaxine Succinate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A4 (ENSG00000108576), SLC6A2 (ENSG00000103546)', 'yearOfFirstApproval': 2008, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_736', 'drugNa... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.930 | Q59 | What is the genetic target of the small molecule drug Vodobatinib, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Vodobatinib: ABL1 and BCR. Vodobatinib reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%vodobatinib%" OR LOWER(tradeNames_string) LIKE "%vodobatinib%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_5367', 'drugName': 'Vodobatinib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ABL1 (ENSG00000097007), BCR (ENSG00000186716)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_5368', 'drugName': 'Vodobatinib'... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1019 | Q59 | What is the genetic target of the protein drug Pramlintide Acetate, and what is its status in clinical trials and FDA approval? | There are 4 genetic targets of the protein drug Pramlintide Acetate: CALCR, RAMP1, RAMP2, and RAMP3. Pramlintide Acetate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%pramlintide acetate%" OR LOWER(tradeNames_string) LIKE "%pramlintide... | [{'UUID': 'DrugGeneTargets_v2_2394', 'drugName': 'Pramlintide Acetate', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'CALCR (ENSG00000004948), RAMP1 (ENSG00000132329), RAMP2 (ENSG00000131477), RAMP3 (ENSG00000122679)', 'yearOfFirstApproval': 2005, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUI... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.132 | Q59 | What is the genetic target of the small molecule drug Pac-14028, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Pac-14028 is TRPV1. Pac-14028 reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%pac-14028%" OR LOWER(tradeNames_string) LIKE "%pac-14028%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_368', 'drugName': 'Pac-14028', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TRPV1 (ENSG00000196689)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1175 | Q59 | What is the genetic target of the small molecule drug Vildagliptin, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Vildagliptin is DPP4. Vildagliptin reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%vildagliptin%" OR LOWER(tradeNames_string) LIKE "%vildagliptin%" OR ... | [{'UUID': 'DrugGeneTargets_v2_4272', 'drugName': 'Vildagliptin', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DPP4 (ENSG00000197635)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.327 | Q59 | What is the genetic target of the small molecule drug Ro-4987655, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Ro-4987655: MAP2K2 and MAP2K1. Ro-4987655 reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ro-4987655%" OR LOWER(tradeNames_string) LIKE "%ro-4987655%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_2635', 'drugName': 'Ro-4987655', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'MAP2K2 (ENSG00000126934), MAP2K1 (ENSG00000169032)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_2636', 'drugName': 'Ro-49876... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1279 | Q59 | What is the genetic target of the small molecule drug Moricizine Hydrochloride, and what is its status in clinical trials and FDA approval? | There are 10 genetic targets of the small molecule drug Moricizine Hydrochloride: SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. Moricizine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%moricizine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%morici... | [{'UUID': 'DrugGeneTargets_v2_2214', 'drugName': 'Moricizine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SCN1A (ENSG00000144285), SCN5A (ENSG00000183873), SCN4A (ENSG00000007314), SCN7A (ENSG00000136546), SCN2A (ENSG00000136531), SCN9A (ENSG00000169432), SCN3A (ENSG00000153253), S... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1385 | Q59 | What is the genetic target of the antibody drug Maslimomab, and what is its status in clinical trials and FDA approval? | There are 4 genetic targets of the antibody drug Maslimomab: TRAV29DV5, TRAC, TRBV7-9, and TRGV3. Maslimomab reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%maslimomab%" OR LOWER(tradeNames_string) LIKE "%maslimomab%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_6249', 'drugName': 'Maslimomab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'TRAV29DV5 (ENSG00000211810), TRAC (ENSG00000277734), TRBV7-9 (ENSG00000278030), TRGV3 (ENSG00000211699)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.951 | Q59 | What is the genetic target of the small molecule drug Finasteride, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Finasteride is SRD5A2. Finasteride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%finasteride%" OR LOWER(tradeNames_string) LIKE "%finasteride%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_5461', 'drugName': 'Finasteride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SRD5A2 (ENSG00000277893)', 'yearOfFirstApproval': 1992, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1867 | Q59 | What is the genetic target of the small molecule drug Echothiophate Iodide, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Echothiophate Iodide is ACHE. Echothiophate Iodide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%echothiophate iodide%" OR LOWER(tradeNames_string) LIKE "%echothioph... | [{'UUID': 'DrugGeneTargets_v2_2129', 'drugName': 'Echothiophate Iodide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ACHE (ENSG00000087085)', 'yearOfFirstApproval': 1960, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1372 | Q59 | What is the genetic target of the small molecule drug Ly2624803, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Ly2624803 is HRH1. Ly2624803 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ly2624803%" OR LOWER(tradeNames_string) LIKE "%ly2624803%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_338', 'drugName': 'Ly2624803', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH1 (ENSG00000196639)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1520 | Q59 | What is the genetic target of the protein drug Voclosporin, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Voclosporin is PPP3CA. Voclosporin reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%voclosporin%" OR LOWER(tradeNames_string) LIKE "%voclosporin%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_3543', 'drugName': 'Voclosporin', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'PPP3CA (ENSG00000138814)', 'yearOfFirstApproval': 2021, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.702 | Q59 | What is the genetic target of the small molecule drug Pha-543613, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Pha-543613 is CHRNA7. Pha-543613 reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%pha-543613%" OR LOWER(tradeNames_string) LIKE "%pha-543613%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_2285', 'drugName': 'Pha-543613', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRNA7 (ENSG00000175344)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.218 | Q59 | What is the genetic target of the small molecule drug Milrinone, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Milrinone is PDE3A. Milrinone reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%milrinone%" OR LOWER(tradeNames_string) LIKE "%milrinone%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_2382', 'drugName': 'Milrinone', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PDE3A (ENSG00000172572)', 'yearOfFirstApproval': 1987, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3912', 'drugName': 'Milrinone Lactate', 'drugMolecular... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1043 | Q59 | What is the genetic target of the small molecule drug Bupropion, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Bupropion: SLC6A2 and SLC6A3. Bupropion reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%bupropion%" OR LOWER(tradeNames_string) LIKE "%bupropion%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_1807', 'drugName': 'Bupropion Hydrobromide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A3 (ENSG00000142319), SLC6A2 (ENSG00000103546)', 'yearOfFirstApproval': 2008, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1627', 'drugNa... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1815 | Q59 | What is the genetic target of the small molecule drug Rivastigmine, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Rivastigmine: BCHE and ACHE. Rivastigmine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%rivastigmine%" OR LOWER(tradeNames_string) LIKE "%rivastigmine%" OR ... | [{'UUID': 'DrugGeneTargets_v2_486', 'drugName': 'Rivastigmine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'BCHE (ENSG00000114200), ACHE (ENSG00000087085)', 'yearOfFirstApproval': 2000, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1705', 'drugName': 'Rivastigm... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.161 | Q59 | What is the genetic target of the small molecule drug Clozapine, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Clozapine: HTR2A and DRD2. Clozapine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%clozapine%" OR LOWER(tradeNames_string) LIKE "%clozapine%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_3784', 'drugName': 'Clozapine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR2A (ENSG00000102468), DRD2 (ENSG00000149295)', 'yearOfFirstApproval': 1989, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3785', 'drugName': 'Clozapine'... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1059 | Q59 | What is the genetic target of the small molecule drug Meprednisone, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Meprednisone is NR3C1. Meprednisone reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%meprednisone%" OR LOWER(tradeNames_string) LIKE "%meprednisone%" OR ... | [{'UUID': 'DrugGeneTargets_v2_5378', 'drugName': 'Meprednisone', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'NR3C1 (ENSG00000113580)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1243 | Q59 | What is the genetic target of the oligonucleotide drug Oblimersen Sodium, and what is its status in clinical trials and FDA approval? | The genetic target of the oligonucleotide drug Oblimersen Sodium is BCL2. Oblimersen Sodium reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%oblimersen sodium%" OR LOWER(tradeNames_string) LIKE "%oblimersen so... | [{'UUID': 'DrugGeneTargets_v2_5823', 'drugName': 'Oblimersen Sodium', 'drugMolecularType': 'Oligonucleotide', 'newLinkedTargets_string': 'BCL2 (ENSG00000171791)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.641 | Q59 | What is the genetic target of the small molecule drug Jnj-39220675, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Jnj-39220675 is HRH3. Jnj-39220675 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%jnj-39220675%" OR LOWER(tradeNames_string) LIKE "%jnj-39220675%" OR ... | [{'UUID': 'DrugGeneTargets_v2_840', 'drugName': 'Jnj-39220675', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH3 (ENSG00000101180)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.522 | Q59 | What is the genetic target of the small molecule drug Estradiol Acetate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Estradiol Acetate is ESR1. Estradiol Acetate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%estradiol acetate%" OR LOWER(tradeNames_string) LIKE "%estradiol ace... | [{'UUID': 'DrugGeneTargets_v2_3260', 'drugName': 'Estradiol Acetate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ESR1 (ENSG00000091831)', 'yearOfFirstApproval': 2003, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1624 | Q59 | What is the genetic target of the small molecule drug Troglitazone, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Troglitazone is PPARG. Troglitazone reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%troglitazone%" OR LOWER(tradeNames_string) LIKE "%troglitazone%" OR ... | [{'UUID': 'DrugGeneTargets_v2_1190', 'drugName': 'Troglitazone', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PPARG (ENSG00000132170)', 'yearOfFirstApproval': 1997, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1522 | Q59 | What is the genetic target of the small molecule drug Epinastine, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Epinastine is HRH1. Epinastine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%epinastine%" OR LOWER(tradeNames_string) LIKE "%epinastine%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_3833', 'drugName': 'Epinastine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH1 (ENSG00000196639)', 'yearOfFirstApproval': 2003, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_5985', 'drugName': 'Epinastine Hydrochloride', 'drugMo... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.604 | Q59 | What is the genetic target of the small molecule drug Articaine Hydrochloride, and what is its status in clinical trials and FDA approval? | There are 10 genetic targets of the small molecule drug Articaine Hydrochloride: SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. Articaine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%articaine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%articai... | [{'UUID': 'DrugGeneTargets_v2_1986', 'drugName': 'Articaine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SCN1A (ENSG00000144285), SCN5A (ENSG00000183873), SCN4A (ENSG00000007314), SCN7A (ENSG00000136546), SCN2A (ENSG00000136531), SCN9A (ENSG00000169432), SCN3A (ENSG00000153253), SC... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.198 | Q59 | What is the genetic target of the protein drug Insulin Zinc Susp Purified Beef/Pork, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Insulin Zinc Susp Purified Beef/Pork is INSR. Insulin Zinc Susp Purified Beef/Pork reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%insulin zinc susp purified beef/pork%" OR LOWER(tradeNames_string) L... | [{'UUID': 'DrugGeneTargets_v2_2821', 'drugName': 'Insulin Zinc Susp Purified Beef/Pork', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'INSR (ENSG00000171105)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1644 | Q59 | What is the genetic target of the antibody drug Itolizumab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Itolizumab is CD6. Itolizumab reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%itolizumab%" OR LOWER(tradeNames_string) LIKE "%itolizumab%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_4017', 'drugName': 'Itolizumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'CD6 (ENSG00000013725)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.961 | Q59 | What is the genetic target of the small molecule drug Modafinil, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Modafinil is SLC6A3. Modafinil reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%modafinil%" OR LOWER(tradeNames_string) LIKE "%modafinil%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_5145', 'drugName': 'Modafinil', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A3 (ENSG00000142319)', 'yearOfFirstApproval': 1998, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2926', 'drugName': 'Armodafinil', 'drugMolecularType'... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.416 | Q59 | What is the genetic target of the small molecule drug Perindopril Erbumine, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Perindopril Erbumine is ACE. Perindopril Erbumine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%perindopril erbumine%" OR LOWER(tradeNames_string) LIKE "%perindopri... | [{'UUID': 'DrugGeneTargets_v2_1718', 'drugName': 'Perindopril Erbumine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ACE (ENSG00000159640)', 'yearOfFirstApproval': 1993, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.99 | Q59 | What is the genetic target of the small molecule drug Afegostat Tartrate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Afegostat Tartrate is GBA1. Afegostat Tartrate reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%afegostat tartrate%" OR LOWER(tradeNames_string) LIKE "%afegostat ta... | [{'UUID': 'DrugGeneTargets_v2_3843', 'drugName': 'Afegostat Tartrate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'GBA1 (ENSG00000177628)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.988 | Q59 | What is the genetic target of the small molecule drug Suvecaltamide, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Suvecaltamide: CACNA1H, CACNA1G, and CACNA1I. Suvecaltamide reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%suvecaltamide%" OR LOWER(tradeNames_string) LIKE "%suvecaltamide%" O... | [{'UUID': 'DrugGeneTargets_v2_2591', 'drugName': 'Suvecaltamide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CACNA1H (ENSG00000196557), CACNA1G (ENSG00000006283), CACNA1I (ENSG00000100346)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.933 | Q59 | What is the genetic target of the small molecule drug Alendronic Acid, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Alendronic Acid is FDPS. Alendronic Acid reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%alendronic acid%" OR LOWER(tradeNames_string) LIKE "%alendronic acid... | [{'UUID': 'DrugGeneTargets_v2_4741', 'drugName': 'Alendronate Sodium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'FDPS (ENSG00000160752)', 'yearOfFirstApproval': 1995, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_5882', 'drugName': 'Alendronic Acid', 'drugMol... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.159 | Q59 | What is the genetic target of the antibody drug Burosumab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Burosumab is FGF23. Burosumab reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%burosumab%" OR LOWER(tradeNames_string) LIKE "%burosumab%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_4495', 'drugName': 'Burosumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'FGF23 (ENSG00000118972)', 'yearOfFirstApproval': 2018, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.425 | Q59 | What is the genetic target of the small molecule drug Nepafenac, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Nepafenac: PTGS2 and PTGS1. Nepafenac reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%nepafenac%" OR LOWER(tradeNames_string) LIKE "%nepafenac%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_5261', 'drugName': 'Nepafenac', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGS2 (ENSG00000073756), PTGS1 (ENSG00000095303)', 'yearOfFirstApproval': 2005, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1804 | Q59 | What is the genetic target of the small molecule drug Tiagabine, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Tiagabine is SLC6A1. Tiagabine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tiagabine%" OR LOWER(tradeNames_string) LIKE "%tiagabine%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_4422', 'drugName': 'Tiagabine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A1 (ENSG00000157103)', 'yearOfFirstApproval': 1997, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3768', 'drugName': 'Tiagabine Hydrochloride', 'drugMo... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.483 | Q59 | What is the genetic target of the small molecule drug Norgestrel, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Norgestrel is PGR. Norgestrel reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%norgestrel%" OR LOWER(tradeNames_string) LIKE "%norgestrel%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_6188', 'drugName': 'Norgestrel', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PGR (ENSG00000082175)', 'yearOfFirstApproval': 1968, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2857', 'drugName': 'Levonorgestrel', 'drugMolecularType... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1512 | Q59 | What is the genetic target of the small molecule drug Rivipansel, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Rivipansel: SELE, SELP, and SELL. Rivipansel reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%rivipansel%" OR LOWER(tradeNames_string) LIKE "%rivipansel%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_2473', 'drugName': 'Rivipansel', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SELE (ENSG00000007908), SELP (ENSG00000174175), SELL (ENSG00000188404)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_2474', '... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.675 | Q59 | What is the genetic target of the small molecule drug Cobicistat, and what is its status in clinical trials and FDA approval? | There are 4 genetic targets of the small molecule drug Cobicistat: CYP3A4, CYP3A5, CYP3A43, and CYP3A7. Cobicistat reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%cobicistat%" OR LOWER(tradeNames_string) LIKE "%cobicistat%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_4493', 'drugName': 'Cobicistat', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CYP3A4 (ENSG00000160868), CYP3A5 (ENSG00000106258), CYP3A43 (ENSG00000021461), CYP3A7 (ENSG00000160870)', 'yearOfFirstApproval': 2012, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1238 | Q59 | What is the genetic target of the small molecule drug Codeine Sulfate, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Codeine Sulfate: OPRK1, OPRD1, and OPRM1. Codeine Sulfate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%codeine sulfate%" OR LOWER(tradeNames_string) LIKE "%codeine sulfate... | [{'UUID': 'DrugGeneTargets_v2_3666', 'drugName': 'Codeine Sulfate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'OPRK1 (ENSG00000082556), OPRD1 (ENSG00000116329), OPRM1 (ENSG00000112038)', 'yearOfFirstApproval': 2009, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1873 | Q59 | What is the genetic target of the small molecule drug Tolterodine, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Tolterodine: CHRM2 and CHRM3. Tolterodine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tolterodine%" OR LOWER(tradeNames_string) LIKE "%tolterodine%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_1507', 'drugName': 'Tolterodine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRM2 (ENSG00000181072), CHRM3 (ENSG00000133019)', 'yearOfFirstApproval': 1998, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1506', 'drugName': 'Toltero... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1299 | Q59 | What is the genetic target of the small molecule drug Tecadenoson, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Tecadenoson is ADORA1. Tecadenoson reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tecadenoson%" OR LOWER(tradeNames_string) LIKE "%tecadenoson%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_275', 'drugName': 'Tecadenoson', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADORA1 (ENSG00000163485)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.453 | Q59 | What is the genetic target of the small molecule drug Ceritinib, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Ceritinib: ALK, EML4, and NPM1. Ceritinib reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ceritinib%" OR LOWER(tradeNames_string) LIKE "%ceritinib%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_2434', 'drugName': 'Ceritinib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ALK (ENSG00000171094), EML4 (ENSG00000143924), NPM1 (ENSG00000181163)', 'yearOfFirstApproval': 2014, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2435', '... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.559 | Q59 | What is the genetic target of the small molecule drug Isoxsuprine Hydrochloride, and what is its status in clinical trials and FDA approval? | There are 4 genetic targets of the small molecule drug Isoxsuprine Hydrochloride: ADRB2, ADRA1A, ADRA1D, and ADRA1B. Isoxsuprine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%isoxsuprine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%isoxs... | [{'UUID': 'DrugGeneTargets_v2_2488', 'drugName': 'Isoxsuprine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRB2 (ENSG00000169252), ADRA1A (ENSG00000120907), ADRA1D (ENSG00000171873), ADRA1B (ENSG00000170214)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved':... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.181 | Q59 | What is the genetic target of the small molecule drug Betazole, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Betazole is HRH2. Betazole reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%betazole%" OR LOWER(tradeNames_string) LIKE "%betazole%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_1660', 'drugName': 'Betazole', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH2 (ENSG00000113749)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3149', 'drugName': 'Betazole Hydrochloride', 'drugMolecu... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.396 | Q59 | What is the genetic target of the small molecule drug Tridihexethyl, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Tridihexethyl: CHRM3 and CHRM1. Tridihexethyl reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tridihexethyl%" OR LOWER(tradeNames_string) LIKE "%tridihexethyl%" O... | [{'UUID': 'DrugGeneTargets_v2_5885', 'drugName': 'Tridihexethyl', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRM3 (ENSG00000133019), CHRM1 (ENSG00000168539)', 'yearOfFirstApproval': 1954, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_5884', 'drugName': 'Tridi... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.584 | Q59 | What is the genetic target of the small molecule drug Sufentanil Citrate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Sufentanil Citrate is OPRM1. Sufentanil Citrate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%sufentanil citrate%" OR LOWER(tradeNames_string) LIKE "%sufentanil c... | [{'UUID': 'DrugGeneTargets_v2_3984', 'drugName': 'Sufentanil Citrate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'OPRM1 (ENSG00000112038)', 'yearOfFirstApproval': 1984, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.995 | Q59 | What is the genetic target of the antibody drug Patritumab Deruxtecan, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the antibody drug Patritumab Deruxtecan: ERBB3 and TOP1. Patritumab Deruxtecan reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%patritumab deruxtecan%" OR LOWER(tradeNames_string) LIKE "%patrituma... | [{'UUID': 'DrugGeneTargets_v2_1952', 'drugName': 'Patritumab Deruxtecan', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'ERBB3 (ENSG00000065361), TOP1 (ENSG00000198900)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_1953', 'drugName': 'Patrit... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1707 | Q59 | What is the genetic target of the antibody drug Emapalumab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Emapalumab is IFNG. Emapalumab reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%emapalumab%" OR LOWER(tradeNames_string) LIKE "%emapalumab%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_3856', 'drugName': 'Emapalumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'IFNG (ENSG00000111537)', 'yearOfFirstApproval': 2018, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1285 | Q59 | What is the genetic target of the small molecule drug Carbimazole, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Carbimazole is TPO. Carbimazole reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%carbimazole%" OR LOWER(tradeNames_string) LIKE "%carbimazole%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_2546', 'drugName': 'Carbimazole', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TPO (ENSG00000115705)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1645 | Q59 | What is the genetic target of the small molecule drug Theophylline Sodium Glycinate, and what is its status in clinical trials and FDA approval? | There are 10 genetic targets of the small molecule drug Theophylline Sodium Glycinate: PDE4A, PDE4D, PDE4B, PDE4C, PDE3A, PDE3B, ADORA1, ADORA2B, ADORA3, and ADORA2A. Theophylline Sodium Glycinate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%theophylline sodium glycinate%" OR LOWER(tradeNames_string) LIKE "%t... | [{'UUID': 'DrugGeneTargets_v2_955', 'drugName': 'Theophylline Sodium Glycinate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PDE4A (ENSG00000065989), PDE4D (ENSG00000113448), PDE4B (ENSG00000184588), PDE4C (ENSG00000105650), PDE3A (ENSG00000172572), PDE3B (ENSG00000152270), ADORA1 (ENSG0000016348... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.886 | Q59 | What is the genetic target of the small molecule drug Sepetaprost, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Sepetaprost: PTGER3 and PTGFR. Sepetaprost reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%sepetaprost%" OR LOWER(tradeNames_string) LIKE "%sepetaprost%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_2979', 'drugName': 'Sepetaprost', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGER3 (ENSG00000050628), PTGFR (ENSG00000122420)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_2980', 'drugName': 'Sepetapr... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.827 | Q59 | What is the genetic target of the small molecule drug Neboglamine, and what is its status in clinical trials and FDA approval? | There are 7 genetic targets of the small molecule drug Neboglamine: GRIN1, GRIN2A, GRIN2B, GRIN2D, GRIN3B, GRIN2C, and GRIN3A. Neboglamine reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%neboglamine%" OR LOWER(tradeNames_string) LIKE "%neboglamine%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_3366', 'drugName': 'Neboglamine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'GRIN1 (ENSG00000176884), GRIN2A (ENSG00000183454), GRIN2B (ENSG00000273079), GRIN2D (ENSG00000105464), GRIN3B (ENSG00000116032), GRIN2C (ENSG00000161509), GRIN3A (ENSG00000198785)', 'yearOf... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1660 | Q59 | What is the genetic target of the small molecule drug Enalapril, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Enalapril is ACE. Enalapril reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%enalapril%" OR LOWER(tradeNames_string) LIKE "%enalapril%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_6274', 'drugName': 'Enalapril Maleate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ACE (ENSG00000159640)', 'yearOfFirstApproval': 1985, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2276', 'drugName': 'Enalaprilat', 'drugMolecular... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.972 | Q59 | What is the genetic target of the small molecule drug Firategrast, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Firategrast: ITGB1, ITGA4, and ITGB7. Firategrast reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%firategrast%" OR LOWER(tradeNames_string) LIKE "%firategrast%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_2077', 'drugName': 'Firategrast', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ITGB1 (ENSG00000150093), ITGA4 (ENSG00000115232), ITGB7 (ENSG00000139626)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_2078... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1049 | Q59 | What is the genetic target of the small molecule drug Rofecoxib, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Rofecoxib is PTGS2. Rofecoxib reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%rofecoxib%" OR LOWER(tradeNames_string) LIKE "%rofecoxib%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_3942', 'drugName': 'Rofecoxib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGS2 (ENSG00000073756)', 'yearOfFirstApproval': 1999, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.671 | Q59 | What is the genetic target of the protein drug Interferon Alfa-2A, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the protein drug Interferon Alfa-2A: IFNAR1 and IFNAR2. Interferon Alfa-2A reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%interferon alfa-2a%" OR LOWER(tradeNames_string) LIKE "%interferon a... | [{'UUID': 'DrugGeneTargets_v2_4676', 'drugName': 'Interferon Alfa-2A', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'IFNAR1 (ENSG00000142166), IFNAR2 (ENSG00000159110)', 'yearOfFirstApproval': 1986, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3511', 'drugName': 'Pegin... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.145 | Q59 | What is the genetic target of the small molecule drug Rilapladib, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Rilapladib is PLA2G7. Rilapladib reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%rilapladib%" OR LOWER(tradeNames_string) LIKE "%rilapladib%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_3181', 'drugName': 'Rilapladib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PLA2G7 (ENSG00000146070)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1518 | Q59 | What is the genetic target of the small molecule drug Betamethasone Benzoate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Betamethasone Benzoate is NR3C1. Betamethasone Benzoate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%betamethasone benzoate%" OR LOWER(tradeNames_string) LIKE "%betameth... | [{'UUID': 'DrugGeneTargets_v2_6074', 'drugName': 'Betamethasone Benzoate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'NR3C1 (ENSG00000113580)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1999 | Q59 | What is the genetic target of the small molecule drug Mirtazapine, and what is its status in clinical trials and FDA approval? | There are 5 genetic targets of the small molecule drug Mirtazapine: ADRA2A, ADRA2C, ADRA2B, HTR2C, and HTR2A. Mirtazapine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%mirtazapine%" OR LOWER(tradeNames_string) LIKE "%mirtazapine%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_4968', 'drugName': 'Mirtazapine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRA2A (ENSG00000150594), ADRA2C (ENSG00000184160), ADRA2B (ENSG00000274286), HTR2C (ENSG00000147246), HTR2A (ENSG00000102468)', 'yearOfFirstApproval': 1996, 'maxClinicalTrialPhase': 4, 'dr... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
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