uuid stringlengths 4 8 | template_uuid stringclasses 40
values | question stringlengths 13 193 | answer stringlengths 29 2.2k | benchmark_query stringlengths 133 622 | execution_results stringlengths 2 1.14M | query_type stringclasses 2
values | sql_category stringclasses 26
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Q59.871 | Q59 | What is the genetic target of the protein drug Cetrorelix Acetate, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Cetrorelix Acetate is GNRHR. Cetrorelix Acetate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%cetrorelix acetate%" OR LOWER(tradeNames_string) LIKE "%cetrorelix a... | [{'UUID': 'DrugGeneTargets_v2_3467', 'drugName': 'Cetrorelix Acetate', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'GNRHR (ENSG00000109163)', 'yearOfFirstApproval': 2000, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.427 | Q59 | What is the genetic target of the small molecule drug Alcaftadine, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Alcaftadine is HRH1. Alcaftadine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%alcaftadine%" OR LOWER(tradeNames_string) LIKE "%alcaftadine%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_5937', 'drugName': 'Alcaftadine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH1 (ENSG00000196639)', 'yearOfFirstApproval': 2010, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.643 | Q59 | What is the genetic target of the small molecule drug Oxatomide, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Oxatomide is HRH1. Oxatomide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%oxatomide%" OR LOWER(tradeNames_string) LIKE "%oxatomide%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_3368', 'drugName': 'Oxatomide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH1 (ENSG00000196639)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1408 | Q59 | What is the genetic target of the antibody drug Anrukinzumab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Anrukinzumab is IL13. Anrukinzumab reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%anrukinzumab%" OR LOWER(tradeNames_string) LIKE "%anrukinzumab%" OR ... | [{'UUID': 'DrugGeneTargets_v2_4273', 'drugName': 'Anrukinzumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'IL13 (ENSG00000169194)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.806 | Q59 | What is the genetic target of the protein drug Interferon Beta-1B, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the protein drug Interferon Beta-1B: IFNAR1 and IFNAR2. Interferon Beta-1B reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%interferon beta-1b%" OR LOWER(tradeNames_string) LIKE "%interferon b... | [{'UUID': 'DrugGeneTargets_v2_5120', 'drugName': 'Interferon Beta-1B', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'IFNAR1 (ENSG00000142166), IFNAR2 (ENSG00000159110)', 'yearOfFirstApproval': 1993, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1067 | Q59 | What is the genetic target of the small molecule drug Pf-00217830, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Pf-00217830 is DRD2. Pf-00217830 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%pf-00217830%" OR LOWER(tradeNames_string) LIKE "%pf-00217830%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_880', 'drugName': 'Pf-00217830', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DRD2 (ENSG00000149295)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.622 | Q59 | What is the genetic target of the small molecule drug Betaine Hydrochloride, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Betaine Hydrochloride: BHMT and BHMT2. Betaine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%betaine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%betaine h... | [{'UUID': 'DrugGeneTargets_v2_1270', 'drugName': 'Betaine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'BHMT (ENSG00000145692), BHMT2 (ENSG00000132840)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.298 | Q59 | What is the genetic target of the antibody drug Ralpancizumab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Ralpancizumab is PCSK9. Ralpancizumab reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ralpancizumab%" OR LOWER(tradeNames_string) LIKE "%ralpancizumab%" O... | [{'UUID': 'DrugGeneTargets_v2_4790', 'drugName': 'Ralpancizumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'PCSK9 (ENSG00000169174)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.912 | Q59 | What is the genetic target of the antibody drug Oregovomab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Oregovomab is MUC16. Oregovomab reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%oregovomab%" OR LOWER(tradeNames_string) LIKE "%oregovomab%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_3687', 'drugName': 'Oregovomab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'MUC16 (ENSG00000181143)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.917 | Q59 | What is the genetic target of the small molecule drug Selinexor, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Selinexor is XPO1. Selinexor reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%selinexor%" OR LOWER(tradeNames_string) LIKE "%selinexor%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_58', 'drugName': 'Selinexor', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'XPO1 (ENSG00000082898)', 'yearOfFirstApproval': 2019, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1903 | Q59 | What is the genetic target of the protein drug Saralasin, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Saralasin is AGTR1. Saralasin reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%saralasin%" OR LOWER(tradeNames_string) LIKE "%saralasin%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_3720', 'drugName': 'Saralasin', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'AGTR1 (ENSG00000144891)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4566', 'drugName': 'Saralasin Acetate', 'drugMolecularType': ... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.91 | Q59 | What is the genetic target of the small molecule drug Fruquintinib, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Fruquintinib: FLT1, FLT4, and KDR. Fruquintinib reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%fruquintinib%" OR LOWER(tradeNames_string) LIKE "%fruquintinib%" OR ... | [{'UUID': 'DrugGeneTargets_v2_1715', 'drugName': 'Fruquintinib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'FLT1 (ENSG00000102755), FLT4 (ENSG00000037280), KDR (ENSG00000128052)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.42 | Q59 | What is the genetic target of the small molecule drug Bimosiamose, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Bimosiamose: SELL, SELE, and SELP. Bimosiamose reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%bimosiamose%" OR LOWER(tradeNames_string) LIKE "%bimosiamose%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_1808', 'drugName': 'Bimosiamose', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SELL (ENSG00000188404), SELE (ENSG00000007908), SELP (ENSG00000174175)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1803 | Q59 | What is the genetic target of the small molecule drug Amg-208, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Amg-208 is MET. Amg-208 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%amg-208%" OR LOWER(tradeNames_string) LIKE "%amg-208%" OR LOWER(drug... | [{'UUID': 'DrugGeneTargets_v2_3939', 'drugName': 'Amg-208', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'MET (ENSG00000105976)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1934 | Q59 | What is the genetic target of the small molecule drug Rucaparib, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Rucaparib: PARP1, PARP3, and PARP2. Rucaparib reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%rucaparib%" OR LOWER(tradeNames_string) LIKE "%rucaparib%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_3166', 'drugName': 'Rucaparib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PARP1 (ENSG00000143799), PARP3 (ENSG00000041880), PARP2 (ENSG00000129484)', 'yearOfFirstApproval': 2016, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_6042... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.134 | Q59 | What is the genetic target of the small molecule drug Dexmedetomidine Hydrochloride, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Dexmedetomidine Hydrochloride: ADRA2A, ADRA2C, and ADRA2B. Dexmedetomidine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%dexmedetomidine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%d... | [{'UUID': 'DrugGeneTargets_v2_6083', 'drugName': 'Dexmedetomidine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRA2A (ENSG00000150594), ADRA2C (ENSG00000184160), ADRA2B (ENSG00000274286)', 'yearOfFirstApproval': 1999, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1566 | Q59 | What is the genetic target of the small molecule drug Edrophonium, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Edrophonium is ACHE. Edrophonium reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%edrophonium%" OR LOWER(tradeNames_string) LIKE "%edrophonium%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_5676', 'drugName': 'Edrophonium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ACHE (ENSG00000087085)', 'yearOfFirstApproval': 1951, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_5141', 'drugName': 'Edrophonium Chloride', 'drugMolec... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.977 | Q59 | What is the genetic target of the small molecule drug Onapristone, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Onapristone is PGR. Onapristone reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%onapristone%" OR LOWER(tradeNames_string) LIKE "%onapristone%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_3728', 'drugName': 'Onapristone', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PGR (ENSG00000082175)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1070 | Q59 | What is the genetic target of the small molecule drug Xylometazoline, and what is its status in clinical trials and FDA approval? | There are 6 genetic targets of the small molecule drug Xylometazoline: ADRA1A, ADRA2A, ADRA2C, ADRA1D, ADRA1B, and ADRA2B. Xylometazoline reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%xylometazoline%" OR LOWER(tradeNames_string) LIKE "%xylometazoline%"... | [{'UUID': 'DrugGeneTargets_v2_4494', 'drugName': 'Xylometazoline', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRA1A (ENSG00000120907), ADRA2A (ENSG00000150594), ADRA2C (ENSG00000184160), ADRA1D (ENSG00000171873), ADRA1B (ENSG00000170214), ADRA2B (ENSG00000274286)', 'yearOfFirstApproval': 0, 'ma... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1856 | Q59 | What is the genetic target of the small molecule drug Tolmetin, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Tolmetin: PTGS2 and PTGS1. Tolmetin reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tolmetin%" OR LOWER(tradeNames_string) LIKE "%tolmetin%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_5527', 'drugName': 'Tolmetin', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGS2 (ENSG00000073756), PTGS1 (ENSG00000095303)', 'yearOfFirstApproval': 1976, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1392', 'drugName': 'Tolmetin S... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1346 | Q59 | What is the genetic target of the small molecule drug Dronabinol, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Dronabinol is CNR1. Dronabinol reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%dronabinol%" OR LOWER(tradeNames_string) LIKE "%dronabinol%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_3038', 'drugName': 'Dronabinol', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CNR1 (ENSG00000118432)', 'yearOfFirstApproval': 1985, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1831 | Q59 | What is the genetic target of the small molecule drug Pramipexole, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Pramipexole: DRD2, DRD3, and DRD4. Pramipexole reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%pramipexole%" OR LOWER(tradeNames_string) LIKE "%pramipexole%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_980', 'drugName': 'Pramipexole', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DRD2 (ENSG00000149295), DRD3 (ENSG00000151577), DRD4 (ENSG00000069696)', 'yearOfFirstApproval': 1997, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_5763',... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.167 | Q59 | What is the genetic target of the antibody drug Daxdilimab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Daxdilimab is LILRA4. Daxdilimab reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%daxdilimab%" OR LOWER(tradeNames_string) LIKE "%daxdilimab%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_2096', 'drugName': 'Daxdilimab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'LILRA4 (ENSG00000239961)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.731 | Q59 | What is the genetic target of the small molecule drug Alfuzosin, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Alfuzosin: ADRA1A, ADRA1D, and ADRA1B. Alfuzosin reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%alfuzosin%" OR LOWER(tradeNames_string) LIKE "%alfuzosin%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_1235', 'drugName': 'Alfuzosin Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRA1A (ENSG00000120907), ADRA1D (ENSG00000171873), ADRA1B (ENSG00000170214)', 'yearOfFirstApproval': 2003, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGe... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.294 | Q59 | What is the genetic target of the antibody drug Medi-565, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the antibody drug Medi-565: CEACAM5 and CD3E. Medi-565 reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%medi-565%" OR LOWER(tradeNames_string) LIKE "%medi-565%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_6252', 'drugName': 'Medi-565', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'CEACAM5 (ENSG00000105388), CD3E (ENSG00000198851)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_6253', 'drugName': 'Medi-565', 'drugM... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1142 | Q59 | What is the genetic target of the small molecule drug Diphenoxylate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Diphenoxylate is OPRM1. Diphenoxylate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%diphenoxylate%" OR LOWER(tradeNames_string) LIKE "%diphenoxylate%" O... | [{'UUID': 'DrugGeneTargets_v2_248', 'drugName': 'Diphenoxylate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'OPRM1 (ENSG00000112038)', 'yearOfFirstApproval': 1960, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4164', 'drugName': 'Diphenoxylate Hydrochloride', '... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1536 | Q59 | What is the genetic target of the small molecule drug Mitapivat Sulfate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Mitapivat Sulfate is PKLR. Mitapivat Sulfate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%mitapivat sulfate%" OR LOWER(tradeNames_string) LIKE "%mitapivat sul... | [{'UUID': 'DrugGeneTargets_v2_2811', 'drugName': 'Mitapivat Sulfate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PKLR (ENSG00000143627)', 'yearOfFirstApproval': 2022, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1897 | Q59 | What is the genetic target of the small molecule drug Imidapril, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Imidapril is ACE. Imidapril reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%imidapril%" OR LOWER(tradeNames_string) LIKE "%imidapril%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_6038', 'drugName': 'Imidapril', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ACE (ENSG00000159640)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1006 | Q59 | What is the genetic target of the antibody drug Canakinumab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Canakinumab is IL1B. Canakinumab reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%canakinumab%" OR LOWER(tradeNames_string) LIKE "%canakinumab%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_5122', 'drugName': 'Canakinumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'IL1B (ENSG00000125538)', 'yearOfFirstApproval': 2009, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1421 | Q59 | What is the genetic target of the protein drug Insulin Susp Isophane Beef/Pork, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Insulin Susp Isophane Beef/Pork is INSR. Insulin Susp Isophane Beef/Pork reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%insulin susp isophane beef/pork%" OR LOWER(tradeNames_string) LIKE "... | [{'UUID': 'DrugGeneTargets_v2_1693', 'drugName': 'Insulin Susp Isophane Beef/Pork', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'INSR (ENSG00000171105)', 'yearOfFirstApproval': 1966, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.785 | Q59 | What is the genetic target of the small molecule drug Chlorpheniramine, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Chlorpheniramine is HRH1. Chlorpheniramine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%chlorpheniramine%" OR LOWER(tradeNames_string) LIKE "%chlorphenirami... | [{'UUID': 'DrugGeneTargets_v2_6213', 'drugName': 'Dexchlorpheniramine Maleate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH1 (ENSG00000196639)', 'yearOfFirstApproval': 1981, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4827', 'drugName': 'Chlorpheniramine'... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.846 | Q59 | What is the genetic target of the small molecule drug Nialamide, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Nialamide: MAOA and MAOB. Nialamide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%nialamide%" OR LOWER(tradeNames_string) LIKE "%nialamide%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_3121', 'drugName': 'Nialamide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'MAOA (ENSG00000189221), MAOB (ENSG00000069535)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.352 | Q59 | What is the genetic target of the small molecule drug Cyclizine Lactate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Cyclizine Lactate is HRH1. Cyclizine Lactate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%cyclizine lactate%" OR LOWER(tradeNames_string) LIKE "%cyclizine lac... | [{'UUID': 'DrugGeneTargets_v2_954', 'drugName': 'Cyclizine Lactate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH1 (ENSG00000196639)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1945 | Q59 | What is the genetic target of the small molecule drug Esmolol, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Esmolol: ADRB1 and ADRB2. Esmolol reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%esmolol%" OR LOWER(tradeNames_string) LIKE "%esmolol%" OR LOWER(drug... | [{'UUID': 'DrugGeneTargets_v2_5672', 'drugName': 'Esmolol', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRB1 (ENSG00000043591), ADRB2 (ENSG00000169252)', 'yearOfFirstApproval': 1986, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_5671', 'drugName': 'Esmolol', '... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.577 | Q59 | What is the genetic target of the small molecule drug Aurothioglucose, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Aurothioglucose is TXNRD1. Aurothioglucose reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%aurothioglucose%" OR LOWER(tradeNames_string) LIKE "%aurothioglucose... | [{'UUID': 'DrugGeneTargets_v2_4389', 'drugName': 'Palonosetron', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR3A (ENSG00000166736)', 'yearOfFirstApproval': 2003, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_5394', 'drugName': 'Aurothioglucose', 'drugMolecula... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1923 | Q59 | What is the genetic target of the small molecule drug Mp-412, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Mp-412: EGFR and ERBB2. Mp-412 reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%mp-412%" OR LOWER(tradeNames_string) LIKE "%mp-412%" OR LOWER(drugSy... | [{'UUID': 'DrugGeneTargets_v2_2946', 'drugName': 'Mp-412', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'EGFR (ENSG00000146648), ERBB2 (ENSG00000141736)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_2945', 'drugName': 'Mp-412', 'drugM... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1888 | Q59 | What is the genetic target of the small molecule drug Cavosonstat, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Cavosonstat is ADH5. Cavosonstat reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%cavosonstat%" OR LOWER(tradeNames_string) LIKE "%cavosonstat%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_197', 'drugName': 'Cavosonstat', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADH5 (ENSG00000197894)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1470 | Q59 | What is the genetic target of the oligonucleotide drug Mipomersen Sodium, and what is its status in clinical trials and FDA approval? | The genetic target of the oligonucleotide drug Mipomersen Sodium is APOB. Mipomersen Sodium reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%mipomersen sodium%" OR LOWER(tradeNames_string) LIKE "%mipomersen so... | [{'UUID': 'DrugGeneTargets_v2_3718', 'drugName': 'Mipomersen Sodium', 'drugMolecularType': 'Oligonucleotide', 'newLinkedTargets_string': 'APOB (ENSG00000084674)', 'yearOfFirstApproval': 2013, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1818 | Q59 | What is the genetic target of the protein drug Histrelin, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Histrelin is GNRHR. Histrelin reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%histrelin%" OR LOWER(tradeNames_string) LIKE "%histrelin%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_4630', 'drugName': 'Histrelin', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'GNRHR (ENSG00000109163)', 'yearOfFirstApproval': 1991, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3420', 'drugName': 'Histrelin Acetate', 'drugMolecularType': ... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1317 | Q59 | What is the genetic target of the small molecule drug Trazodone, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Trazodone: HTR2A, HTR2C, and SLC6A4. Trazodone reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%trazodone%" OR LOWER(tradeNames_string) LIKE "%trazodone%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_1293', 'drugName': 'Trazodone', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR2A (ENSG00000102468), HTR2C (ENSG00000147246), SLC6A4 (ENSG00000108576)', 'yearOfFirstApproval': 1981, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_497... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1501 | Q59 | What is the genetic target of the small molecule drug Arhalofenate, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Arhalofenate: PPARG and SLC22A12. Arhalofenate reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%arhalofenate%" OR LOWER(tradeNames_string) LIKE "%arhalofenate%" OR ... | [{'UUID': 'DrugGeneTargets_v2_3126', 'drugName': 'Arhalofenate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PPARG (ENSG00000132170), SLC22A12 (ENSG00000197891)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_3127', 'drugName': 'Arhal... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.464 | Q59 | What is the genetic target of the small molecule drug Methylnaltrexone Bromide, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Methylnaltrexone Bromide is OPRM1. Methylnaltrexone Bromide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%methylnaltrexone bromide%" OR LOWER(tradeNames_string) LIKE "%methyl... | [{'UUID': 'DrugGeneTargets_v2_2413', 'drugName': 'Methylnaltrexone Bromide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'OPRM1 (ENSG00000112038)', 'yearOfFirstApproval': 2008, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.381 | Q59 | What is the genetic target of the protein drug Insulin Susp Protamine Zinc Purified Beef, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Insulin Susp Protamine Zinc Purified Beef is INSR. Insulin Susp Protamine Zinc Purified Beef reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%insulin susp protamine zinc purified beef%" OR LOWER(tradeNames_stri... | [{'UUID': 'DrugGeneTargets_v2_3637', 'drugName': 'Insulin Susp Protamine Zinc Purified Beef', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'INSR (ENSG00000171105)', 'yearOfFirstApproval': 1980, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1344 | Q59 | What is the genetic target of the antibody drug Mdx-447, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the antibody drug Mdx-447: EGFR and FCGR1A. Mdx-447 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%mdx-447%" OR LOWER(tradeNames_string) LIKE "%mdx-447%" OR LOWER(drug... | [{'UUID': 'DrugGeneTargets_v2_4871', 'drugName': 'Mdx-447', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'EGFR (ENSG00000146648), FCGR1A (ENSG00000150337)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_4872', 'drugName': 'Mdx-447', 'drugMole... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.337 | Q59 | What is the genetic target of the antibody drug Relatlimab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Relatlimab is LAG3. Relatlimab reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%relatlimab%" OR LOWER(tradeNames_string) LIKE "%relatlimab%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_2446', 'drugName': 'Relatlimab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'LAG3 (ENSG00000089692)', 'yearOfFirstApproval': 2022, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1284 | Q59 | What is the genetic target of the oligonucleotide drug Cofirasersen, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the oligonucleotide drug Cofirasersen: SCNN1G, SCNN1A, and SCNN1B. Cofirasersen reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%cofirasersen%" OR LOWER(tradeNames_string) LIKE "%cofirasersen%" OR ... | [{'UUID': 'DrugGeneTargets_v2_1778', 'drugName': 'Cofirasersen', 'drugMolecularType': 'Oligonucleotide', 'newLinkedTargets_string': 'SCNN1G (ENSG00000166828), SCNN1A (ENSG00000111319), SCNN1B (ENSG00000168447)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1762 | Q59 | What is the genetic target of the small molecule drug Hydroxyurea, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Hydroxyurea: RRM1, RRM2B, and RRM2. Hydroxyurea reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%hydroxyurea%" OR LOWER(tradeNames_string) LIKE "%hydroxyurea%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_5698', 'drugName': 'Hydroxyurea', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'RRM1 (ENSG00000167325), RRM2B (ENSG00000048392), RRM2 (ENSG00000171848)', 'yearOfFirstApproval': 1967, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1459 | Q59 | What is the genetic target of the small molecule drug Bazedoxifene, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Bazedoxifene: ESR2 and ESR1. Bazedoxifene reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%bazedoxifene%" OR LOWER(tradeNames_string) LIKE "%bazedoxifene%" OR ... | [{'UUID': 'DrugGeneTargets_v2_1341', 'drugName': 'Bazedoxifene Acetate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ESR2 (ENSG00000140009), ESR1 (ENSG00000091831)', 'yearOfFirstApproval': 2009, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_5980', 'drugName': '... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.823 | Q59 | What is the genetic target of the protein drug Labradimil, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Labradimil is BDKRB2. Labradimil reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%labradimil%" OR LOWER(tradeNames_string) LIKE "%labradimil%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_548', 'drugName': 'Labradimil', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'BDKRB2 (ENSG00000168398)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1114 | Q59 | What is the genetic target of the small molecule drug Meclofenamate Sodium, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Meclofenamate Sodium: ALOX5, PTGS2, and PTGS1. Meclofenamate Sodium reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%meclofenamate sodium%" OR LOWER(tradeNames_string) LIKE "%meclofenam... | [{'UUID': 'DrugGeneTargets_v2_3724', 'drugName': 'Meclofenamate Sodium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ALOX5 (ENSG00000012779), PTGS2 (ENSG00000073756), PTGS1 (ENSG00000095303)', 'yearOfFirstApproval': 1980, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTarg... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1524 | Q59 | What is the genetic target of the small molecule drug Axitinib, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Axitinib: FLT1, FLT4, and KDR. Axitinib reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%axitinib%" OR LOWER(tradeNames_string) LIKE "%axitinib%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_4943', 'drugName': 'Axitinib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'FLT1 (ENSG00000102755), FLT4 (ENSG00000037280), KDR (ENSG00000128052)', 'yearOfFirstApproval': 2012, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1941 | Q59 | What is the genetic target of the oligonucleotide drug Edifoligide, and what is its status in clinical trials and FDA approval? | There are 8 genetic targets of the oligonucleotide drug Edifoligide: E2F1, E2F2, E2F3, E2F4, E2F5, E2F6, E2F7, and E2F8. Edifoligide reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%edifoligide%" OR LOWER(tradeNames_string) LIKE "%edifoligide%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_4614', 'drugName': 'Edifoligide Sodium', 'drugMolecularType': 'Oligonucleotide', 'newLinkedTargets_string': 'E2F1 (ENSG00000101412), E2F2 (ENSG00000007968), E2F3 (ENSG00000112242), E2F4 (ENSG00000205250), E2F5 (ENSG00000133740), E2F6 (ENSG00000169016), E2F7 (ENSG00000165891), E2F8 (ENSG000... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1616 | Q59 | What is the genetic target of the small molecule drug Lazertinib, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Lazertinib is EGFR. Lazertinib reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%lazertinib%" OR LOWER(tradeNames_string) LIKE "%lazertinib%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_4340', 'drugName': 'Lazertinib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'EGFR (ENSG00000146648)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1898 | Q59 | What is the genetic target of the small molecule drug Serdexmethylphenidate, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Serdexmethylphenidate: SLC6A3 and SLC6A2. Serdexmethylphenidate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%serdexmethylphenidate%" OR LOWER(tradeNames_string) LIKE "%serdexmet... | [{'UUID': 'DrugGeneTargets_v2_2117', 'drugName': 'Serdexmethylphenidate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A3 (ENSG00000142319), SLC6A2 (ENSG00000103546)', 'yearOfFirstApproval': 2021, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2116', 'drugNam... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.918 | Q59 | What is the genetic target of the small molecule drug Glipizide, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Glipizide: KCNJ11 and ABCC8. Glipizide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%glipizide%" OR LOWER(tradeNames_string) LIKE "%glipizide%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_1628', 'drugName': 'Glipizide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'KCNJ11 (ENSG00000187486), ABCC8 (ENSG00000006071)', 'yearOfFirstApproval': 1984, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1930 | Q59 | What is the genetic target of the small molecule drug Enzalutamide, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Enzalutamide is AR. Enzalutamide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%enzalutamide%" OR LOWER(tradeNames_string) LIKE "%enzalutamide%" OR ... | [{'UUID': 'DrugGeneTargets_v2_4352', 'drugName': 'Enzalutamide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'AR (ENSG00000169083)', 'yearOfFirstApproval': 2012, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1126 | Q59 | What is the genetic target of the small molecule drug Brequinar, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Brequinar is DHODH. Brequinar reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%brequinar%" OR LOWER(tradeNames_string) LIKE "%brequinar%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_371', 'drugName': 'Brequinar', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DHODH (ENSG00000102967)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.332 | Q59 | What is the genetic target of the small molecule drug Rosuvastatin, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Rosuvastatin is HMGCR. Rosuvastatin reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%rosuvastatin%" OR LOWER(tradeNames_string) LIKE "%rosuvastatin%" OR ... | [{'UUID': 'DrugGeneTargets_v2_5208', 'drugName': 'Rosuvastatin Calcium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HMGCR (ENSG00000113161)', 'yearOfFirstApproval': 2003, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_6280', 'drugName': 'Rosuvastatin', 'drugMol... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1036 | Q59 | What is the genetic target of the small molecule drug Pecavaptan, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Pecavaptan: AVPR1A and AVPR2. Pecavaptan reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%pecavaptan%" OR LOWER(tradeNames_string) LIKE "%pecavaptan%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_539', 'drugName': 'Pecavaptan', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'AVPR1A (ENSG00000166148), AVPR2 (ENSG00000126895)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_540', 'drugName': 'Pecavaptan'... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.322 | Q59 | What is the genetic target of the small molecule drug Balovaptan, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Balovaptan is AVPR1A. Balovaptan reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%balovaptan%" OR LOWER(tradeNames_string) LIKE "%balovaptan%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_695', 'drugName': 'Balovaptan', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'AVPR1A (ENSG00000166148)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1531 | Q59 | What is the genetic target of the small molecule drug Carprofen, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Carprofen is PTGS2. Carprofen reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%carprofen%" OR LOWER(tradeNames_string) LIKE "%carprofen%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_354', 'drugName': 'Carprofen', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGS2 (ENSG00000073756)', 'yearOfFirstApproval': 1987, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1360 | Q59 | What is the genetic target of the oligosaccharide drug Bemiparin Sodium, and what is its status in clinical trials and FDA approval? | The genetic target of the oligosaccharide drug Bemiparin Sodium is SERPINC1. Bemiparin Sodium reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%bemiparin sodium%" OR LOWER(tradeNames_string) LIKE "%bemiparin sodi... | [{'UUID': 'DrugGeneTargets_v2_2284', 'drugName': 'Bemiparin Sodium', 'drugMolecularType': 'Oligosaccharide', 'newLinkedTargets_string': 'SERPINC1 (ENSG00000117601)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1734 | Q59 | What is the genetic target of the small molecule drug Lenvatinib Mesylate, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Lenvatinib Mesylate: FLT1, FLT4, and KDR. Lenvatinib Mesylate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%lenvatinib mesylate%" OR LOWER(tradeNames_string) LIKE "%lenvatinib ... | [{'UUID': 'DrugGeneTargets_v2_3026', 'drugName': 'Lenvatinib Mesylate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'FLT1 (ENSG00000102755), FLT4 (ENSG00000037280), KDR (ENSG00000128052)', 'yearOfFirstApproval': 2015, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.170 | Q59 | What is the genetic target of the small molecule drug Azd-1080, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Azd-1080: GSK3A and GSK3B. Azd-1080 reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%azd-1080%" OR LOWER(tradeNames_string) LIKE "%azd-1080%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_815', 'drugName': 'Azd-1080', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'GSK3A (ENSG00000105723), GSK3B (ENSG00000082701)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.13 | Q59 | What is the genetic target of the protein drug Menotropins, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the protein drug Menotropins: LHCGR and FSHR. Menotropins reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%menotropins%" OR LOWER(tradeNames_string) LIKE "%menotropins%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_1661', 'drugName': 'Lh (Menotropins)', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'LHCGR (ENSG00000138039)', 'yearOfFirstApproval': 1975, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_206', 'drugName': 'Follitropin Alfa', 'drugMolecularTy... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1927 | Q59 | What is the genetic target of the protein drug Peginterferon Alfa-2B, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the protein drug Peginterferon Alfa-2B: IFNAR1 and IFNAR2. Peginterferon Alfa-2B reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%peginterferon alfa-2b%" OR LOWER(tradeNames_string) LIKE "%peginterf... | [{'UUID': 'DrugGeneTargets_v2_2953', 'drugName': 'Peginterferon Alfa-2B', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'IFNAR1 (ENSG00000142166), IFNAR2 (ENSG00000159110)', 'yearOfFirstApproval': 2001, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_5976', 'drugName': 'Ro... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.174 | Q59 | What is the genetic target of the small molecule drug Derazantinib, and what is its status in clinical trials and FDA approval? | There are 4 genetic targets of the small molecule drug Derazantinib: FGFR3, FGFR1, FGFR4, and FGFR2. Derazantinib reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%derazantinib%" OR LOWER(tradeNames_string) LIKE "%derazantinib%" OR ... | [{'UUID': 'DrugGeneTargets_v2_5518', 'drugName': 'Derazantinib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'FGFR3 (ENSG00000068078), FGFR1 (ENSG00000077782), FGFR4 (ENSG00000160867), FGFR2 (ENSG00000066468)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.656 | Q59 | What is the genetic target of the small molecule drug Verapamil, and what is its status in clinical trials and FDA approval? | There are 4 genetic targets of the small molecule drug Verapamil: CACNA1C, CACNA1S, CACNA1D, and CACNA1F. Verapamil reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%verapamil%" OR LOWER(tradeNames_string) LIKE "%verapamil%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_4356', 'drugName': 'Verapamil Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CACNA1C (ENSG00000151067), CACNA1S (ENSG00000081248), CACNA1D (ENSG00000157388), CACNA1F (ENSG00000102001)', 'yearOfFirstApproval': 1981, 'maxClinicalTrialPhase': 4, 'drugIsAppr... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1062 | Q59 | What is the genetic target of the protein drug Tm30339, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Tm30339 is NPY4R. Tm30339 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tm30339%" OR LOWER(tradeNames_string) LIKE "%tm30339%" OR LOWER(drug... | [{'UUID': 'DrugGeneTargets_v2_2735', 'drugName': 'Tm30339', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'NPY4R (ENSG00000204174)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.263 | Q59 | What is the genetic target of the small molecule drug Dabrafenib Mesylate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Dabrafenib Mesylate is BRAF. Dabrafenib Mesylate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%dabrafenib mesylate%" OR LOWER(tradeNames_string) LIKE "%dabrafenib ... | [{'UUID': 'DrugGeneTargets_v2_441', 'drugName': 'Dabrafenib Mesylate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'BRAF (ENSG00000157764)', 'yearOfFirstApproval': 2013, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1427 | Q59 | What is the genetic target of the small molecule drug Umbralisib, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Umbralisib: CSNK1E, PIK3CD, and ABL1. Umbralisib reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%umbralisib%" OR LOWER(tradeNames_string) LIKE "%umbralisib%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_5649', 'drugName': 'Umbralisib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CSNK1E (ENSG00000213923), PIK3CD (ENSG00000171608), ABL1 (ENSG00000097007)', 'yearOfFirstApproval': 2021, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_30... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1582 | Q59 | What is the genetic target of the protein drug Pegbelfermin, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the protein drug Pegbelfermin: FGF1 and KLB. Pegbelfermin reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%pegbelfermin%" OR LOWER(tradeNames_string) LIKE "%pegbelfermin%" OR ... | [{'UUID': 'DrugGeneTargets_v2_6330', 'drugName': 'Pegbelfermin', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'FGF1 (ENSG00000113578), KLB (ENSG00000134962)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.909 | Q59 | What is the genetic target of the small molecule drug Levonordefrin, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Levonordefrin: ADRA2A, ADRA2C, and ADRA2B. Levonordefrin reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%levonordefrin%" OR LOWER(tradeNames_string) LIKE "%levonordefrin%" O... | [{'UUID': 'DrugGeneTargets_v2_4563', 'drugName': 'Levonordefrin', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRA2A (ENSG00000150594), ADRA2C (ENSG00000184160), ADRA2B (ENSG00000274286)', 'yearOfFirstApproval': 1960, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.679 | Q59 | What is the genetic target of the small molecule drug Procainamide, and what is its status in clinical trials and FDA approval? | There are 10 genetic targets of the small molecule drug Procainamide: SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. Procainamide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%procainamide%" OR LOWER(tradeNames_string) LIKE "%procainamide%" OR ... | [{'UUID': 'DrugGeneTargets_v2_4967', 'drugName': 'Procainamide Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SCN1A (ENSG00000144285), SCN5A (ENSG00000183873), SCN4A (ENSG00000007314), SCN7A (ENSG00000136546), SCN2A (ENSG00000136531), SCN9A (ENSG00000169432), SCN3A (ENSG00000153253),... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.261 | Q59 | What is the genetic target of the small molecule drug Cangrelor, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Cangrelor is P2RY12. Cangrelor reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%cangrelor%" OR LOWER(tradeNames_string) LIKE "%cangrelor%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_1075', 'drugName': 'Cangrelor Tetrasodium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'P2RY12 (ENSG00000169313)', 'yearOfFirstApproval': 2015, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1523', 'drugName': 'Cangrelor', 'drugMole... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.851 | Q59 | What is the genetic target of the small molecule drug Fingolimod Lauryl Sulfate, and what is its status in clinical trials and FDA approval? | There are 5 genetic targets of the small molecule drug Fingolimod Lauryl Sulfate: S1PR5, S1PR2, S1PR4, S1PR3, and S1PR1. Fingolimod Lauryl Sulfate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%fingolimod lauryl sulfate%" OR LOWER(tradeNames_string) LIKE "%fingo... | [{'UUID': 'DrugGeneTargets_v2_5906', 'drugName': 'Fingolimod Lauryl Sulfate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'S1PR5 (ENSG00000180739), S1PR2 (ENSG00000267534), S1PR4 (ENSG00000125910), S1PR3 (ENSG00000213694), S1PR1 (ENSG00000170989)', 'yearOfFirstApproval': 2021, 'maxClinicalTrialPha... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.874 | Q59 | What is the genetic target of the small molecule drug Aliskiren Fumarate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Aliskiren Fumarate is REN. Aliskiren Fumarate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%aliskiren fumarate%" OR LOWER(tradeNames_string) LIKE "%aliskiren fu... | [{'UUID': 'DrugGeneTargets_v2_4221', 'drugName': 'Aliskiren Fumarate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'REN (ENSG00000143839)', 'yearOfFirstApproval': 2007, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1564 | Q59 | What is the genetic target of the small molecule drug Blonanserin, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Blonanserin: DRD2, DRD3, and HTR2A. Blonanserin reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%blonanserin%" OR LOWER(tradeNames_string) LIKE "%blonanserin%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_882', 'drugName': 'Blonanserin', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DRD2 (ENSG00000149295), DRD3 (ENSG00000151577), HTR2A (ENSG00000102468)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_883', '... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.141 | Q59 | What is the genetic target of the protein drug Angiotensin Ii, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Angiotensin Ii is AGTR1. Angiotensin Ii reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%angiotensin ii%" OR LOWER(tradeNames_string) LIKE "%angiotensin ii%"... | [{'UUID': 'DrugGeneTargets_v2_3311', 'drugName': 'Angiotensin Ii', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'AGTR1 (ENSG00000144891)', 'yearOfFirstApproval': 2017, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3664', 'drugName': 'Angiotensin Ii Acetate', 'drugMolecu... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.900 | Q59 | What is the genetic target of the small molecule drug Clomiphene, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Clomiphene is ESR1. Clomiphene reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%clomiphene%" OR LOWER(tradeNames_string) LIKE "%clomiphene%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_2969', 'drugName': 'Clomiphene', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ESR1 (ENSG00000091831)', 'yearOfFirstApproval': 1967, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_6194', 'drugName': 'Clomiphene Citrate', 'drugMolecula... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1839 | Q59 | What is the genetic target of the antibody drug Utomilumab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Utomilumab is TNFRSF9. Utomilumab reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%utomilumab%" OR LOWER(tradeNames_string) LIKE "%utomilumab%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_2445', 'drugName': 'Utomilumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'TNFRSF9 (ENSG00000049249)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.555 | Q59 | What is the genetic target of the small molecule drug Alosetron Hydrochloride, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Alosetron Hydrochloride is HTR3A. Alosetron Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%alosetron hydrochloride%" OR LOWER(tradeNames_string) LIKE "%alosetr... | [{'UUID': 'DrugGeneTargets_v2_5986', 'drugName': 'Alosetron Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR3A (ENSG00000166736)', 'yearOfFirstApproval': 2000, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.323 | Q59 | What is the genetic target of the small molecule drug Norethindrone Acetate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Norethindrone Acetate is PGR. Norethindrone Acetate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%norethindrone acetate%" OR LOWER(tradeNames_string) LIKE "%norethind... | [{'UUID': 'DrugGeneTargets_v2_2855', 'drugName': 'Norethindrone Acetate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PGR (ENSG00000082175)', 'yearOfFirstApproval': 1973, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1854 | Q59 | What is the genetic target of the small molecule drug Saf312, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Saf312 is TRPV1. Saf312 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%saf312%" OR LOWER(tradeNames_string) LIKE "%saf312%" OR LOWER(drugSy... | [{'UUID': 'DrugGeneTargets_v2_2870', 'drugName': 'Saf312', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TRPV1 (ENSG00000196689)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1235 | Q59 | What is the genetic target of the small molecule drug Abemaciclib, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Abemaciclib: CDK4 and CDK6. Abemaciclib reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%abemaciclib%" OR LOWER(tradeNames_string) LIKE "%abemaciclib%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_6006', 'drugName': 'Abemaciclib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CDK4 (ENSG00000135446), CDK6 (ENSG00000105810)', 'yearOfFirstApproval': 2017, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_6007', 'drugName': 'Abemacicl... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1726 | Q59 | What is the genetic target of the small molecule drug Pelabresib, and what is its status in clinical trials and FDA approval? | There are 4 genetic targets of the small molecule drug Pelabresib: BRD2, BRD4, BRDT, and BRD3. Pelabresib reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%pelabresib%" OR LOWER(tradeNames_string) LIKE "%pelabresib%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_866', 'drugName': 'Pelabresib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'BRD2 (ENSG00000204256), BRD4 (ENSG00000141867), BRDT (ENSG00000137948), BRD3 (ENSG00000169925)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.564 | Q59 | What is the genetic target of the small molecule drug Maralixibat, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Maralixibat is SLC10A2. Maralixibat reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%maralixibat%" OR LOWER(tradeNames_string) LIKE "%maralixibat%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_5944', 'drugName': 'Maralixibat Chloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC10A2 (ENSG00000125255)', 'yearOfFirstApproval': 2021, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_5835', 'drugName': 'Maralixibat', 'drugMo... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.142 | Q59 | What is the genetic target of the small molecule drug Hexafluorenium Bromide, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Hexafluorenium Bromide is ACHE. Hexafluorenium Bromide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%hexafluorenium bromide%" OR LOWER(tradeNames_string) LIKE "%hexafluo... | [{'UUID': 'DrugGeneTargets_v2_4592', 'drugName': 'Hexafluorenium Bromide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ACHE (ENSG00000087085)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1736 | Q59 | What is the genetic target of the small molecule drug Methdilazine Hydrochloride, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Methdilazine Hydrochloride is HRH1. Methdilazine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%methdilazine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%meth... | [{'UUID': 'DrugGeneTargets_v2_6240', 'drugName': 'Methdilazine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH1 (ENSG00000196639)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.537 | Q59 | What is the genetic target of the small molecule drug Idasanutlin, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Idasanutlin: TP53 and MDM2. Idasanutlin reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%idasanutlin%" OR LOWER(tradeNames_string) LIKE "%idasanutlin%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_3191', 'drugName': 'Idasanutlin', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TP53 (ENSG00000141510), MDM2 (ENSG00000135679)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.227 | Q59 | What is the genetic target of the small molecule drug Aliskiren, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Aliskiren is REN. Aliskiren reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%aliskiren%" OR LOWER(tradeNames_string) LIKE "%aliskiren%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_2731', 'drugName': 'Aliskiren', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'REN (ENSG00000143839)', 'yearOfFirstApproval': 2007, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4221', 'drugName': 'Aliskiren Fumarate', 'drugMolecularT... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.730 | Q59 | What is the genetic target of the small molecule drug Bromperidol, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Bromperidol is DRD2. Bromperidol reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%bromperidol%" OR LOWER(tradeNames_string) LIKE "%bromperidol%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_4284', 'drugName': 'Bromperidol', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DRD2 (ENSG00000149295)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.793 | Q59 | What is the genetic target of the small molecule drug Abiraterone, and what is its status in clinical trials and FDA approval? | There are 5 genetic targets of the small molecule drug Abiraterone: AR, CYP17A1, SRD5A1, SRD5A2, and SRD5A3. Abiraterone reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%abiraterone%" OR LOWER(tradeNames_string) LIKE "%abiraterone%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_6320', 'drugName': 'Abiraterone', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'AR (ENSG00000169083), CYP17A1 (ENSG00000148795), SRD5A1 (ENSG00000145545), SRD5A2 (ENSG00000277893), SRD5A3 (ENSG00000128039)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIs... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1718 | Q59 | What is the genetic target of the protein drug Eptacog Alfa (Activated), and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Eptacog Alfa (Activated) is F7. Eptacog Alfa (Activated) reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%eptacog alfa (activated)%" OR LOWER(tradeNames_string) LIKE "%eptaco... | [{'UUID': 'DrugGeneTargets_v2_2829', 'drugName': 'Eptacog Alfa (Activated)', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'F7 (ENSG00000057593)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_475', 'drugName': 'Eptacog Alfa', 'drugMolecularType... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.994 | Q59 | What is the genetic target of the small molecule drug Desoximetasone, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Desoximetasone is NR3C1. Desoximetasone reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%desoximetasone%" OR LOWER(tradeNames_string) LIKE "%desoximetasone%"... | [{'UUID': 'DrugGeneTargets_v2_5225', 'drugName': 'Desoximetasone', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'NR3C1 (ENSG00000113580)', 'yearOfFirstApproval': 1977, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.415 | Q59 | What is the genetic target of the small molecule drug Pravastatin, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Pravastatin is HMGCR. Pravastatin reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%pravastatin%" OR LOWER(tradeNames_string) LIKE "%pravastatin%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_5677', 'drugName': 'Pravastatin', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HMGCR (ENSG00000113161)', 'yearOfFirstApproval': 1991, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1605', 'drugName': 'Pravastatin Sodium', 'drugMolecu... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.329 | Q59 | What is the genetic target of the small molecule drug Dimethylcurcumin, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Dimethylcurcumin is AR. Dimethylcurcumin reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%dimethylcurcumin%" OR LOWER(tradeNames_string) LIKE "%dimethylcurcum... | [{'UUID': 'DrugGeneTargets_v2_5293', 'drugName': 'Dimethylcurcumin', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'AR (ENSG00000169083)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1098 | Q59 | What is the genetic target of the small molecule drug Osilodrostat Phosphate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Osilodrostat Phosphate is CYP11B1. Osilodrostat Phosphate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%osilodrostat phosphate%" OR LOWER(tradeNames_string) LIKE "%osilodro... | [{'UUID': 'DrugGeneTargets_v2_5216', 'drugName': 'Osilodrostat Phosphate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CYP11B1 (ENSG00000160882)', 'yearOfFirstApproval': 2020, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.303 | Q59 | What is the genetic target of the small molecule drug Tramiprosate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Tramiprosate is APP. Tramiprosate reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tramiprosate%" OR LOWER(tradeNames_string) LIKE "%tramiprosate%" OR ... | [{'UUID': 'DrugGeneTargets_v2_3123', 'drugName': 'Tramiprosate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'APP (ENSG00000142192)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_4034', 'drugName': 'Valiltramiprosate', 'drugMolecularT... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1259 | Q59 | What is the genetic target of the small molecule drug Dilevalol Hydrochloride, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Dilevalol Hydrochloride: ADRB2, ADRB1, and ADRB3. Dilevalol Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%dilevalol hydrochloride%" OR LOWER(tradeNames_string) LIKE "%dileval... | [{'UUID': 'DrugGeneTargets_v2_3364', 'drugName': 'Dilevalol Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRB2 (ENSG00000169252), ADRB1 (ENSG00000043591), ADRB3 (ENSG00000188778)', 'yearOfFirstApproval': 1990, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneT... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
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