uuid stringlengths 4 8 | template_uuid stringclasses 40
values | question stringlengths 13 193 | answer stringlengths 29 2.2k | benchmark_query stringlengths 133 622 | execution_results stringlengths 2 1.14M | query_type stringclasses 2
values | sql_category stringclasses 26
values | bio_category stringclasses 14
values |
|---|---|---|---|---|---|---|---|---|
Q59.1996 | Q59 | What is the genetic target of the small molecule drug Remifentanil, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Remifentanil is OPRM1. Remifentanil reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%remifentanil%" OR LOWER(tradeNames_string) LIKE "%remifentanil%" OR ... | [{'UUID': 'DrugGeneTargets_v2_1391', 'drugName': 'Remifentanil', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'OPRM1 (ENSG00000112038)', 'yearOfFirstApproval': 1996, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_577', 'drugName': 'Remifentanil Hydrochloride', 'dr... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.26 | Q59 | What is the genetic target of the small molecule drug Eluxadoline, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Eluxadoline is OPRM1. Eluxadoline reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%eluxadoline%" OR LOWER(tradeNames_string) LIKE "%eluxadoline%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_6255', 'drugName': 'Eluxadoline', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'OPRM1 (ENSG00000112038)', 'yearOfFirstApproval': 2015, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1860 | Q59 | What is the genetic target of the protein drug Somatrem, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Somatrem is GHR. Somatrem reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%somatrem%" OR LOWER(tradeNames_string) LIKE "%somatrem%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_959', 'drugName': 'Somatrem', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'GHR (ENSG00000112964)', 'yearOfFirstApproval': 1985, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.721 | Q59 | What is the genetic target of the small molecule drug Maralixibat Chloride, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Maralixibat Chloride is SLC10A2. Maralixibat Chloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%maralixibat chloride%" OR LOWER(tradeNames_string) LIKE "%maralixiba... | [{'UUID': 'DrugGeneTargets_v2_5944', 'drugName': 'Maralixibat Chloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC10A2 (ENSG00000125255)', 'yearOfFirstApproval': 2021, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.996 | Q59 | What is the genetic target of the small molecule drug Pargyline, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Pargyline: MAOA and MAOB. Pargyline reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%pargyline%" OR LOWER(tradeNames_string) LIKE "%pargyline%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_5670', 'drugName': 'Pargyline', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'MAOA (ENSG00000189221), MAOB (ENSG00000069535)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1196', 'drugName': 'Pargyline H... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.196 | Q59 | What is the genetic target of the small molecule drug Chlormadinone Acetate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Chlormadinone Acetate is PGR. Chlormadinone Acetate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%chlormadinone acetate%" OR LOWER(tradeNames_string) LIKE "%chlormadi... | [{'UUID': 'DrugGeneTargets_v2_3940', 'drugName': 'Chlormadinone Acetate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PGR (ENSG00000082175)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.446 | Q59 | What is the genetic target of the small molecule drug Ibufenac, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Ibufenac: PTGS2 and PTGS1. Ibufenac reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ibufenac%" OR LOWER(tradeNames_string) LIKE "%ibufenac%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_3586', 'drugName': 'Ibufenac', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGS2 (ENSG00000073756), PTGS1 (ENSG00000095303)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.579 | Q59 | What is the genetic target of the small molecule drug Anacetrapib, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Anacetrapib is CETP. Anacetrapib reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%anacetrapib%" OR LOWER(tradeNames_string) LIKE "%anacetrapib%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_2858', 'drugName': 'Anacetrapib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CETP (ENSG00000087237)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.955 | Q59 | What is the genetic target of the antibody drug Neihulizumab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Neihulizumab is SELPLG. Neihulizumab reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%neihulizumab%" OR LOWER(tradeNames_string) LIKE "%neihulizumab%" OR ... | [{'UUID': 'DrugGeneTargets_v2_3018', 'drugName': 'Neihulizumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'SELPLG (ENSG00000110876)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.509 | Q59 | What is the genetic target of the antibody drug Labetuzumab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Labetuzumab is CEACAM5. Labetuzumab reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%labetuzumab%" OR LOWER(tradeNames_string) LIKE "%labetuzumab%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_4444', 'drugName': 'Labetuzumab Govitecan', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'CEACAM5 (ENSG00000105388)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_4322', 'drugName': 'Labetuzumab', 'drugMolecular... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.612 | Q59 | What is the genetic target of the protein drug Albiglutide, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Albiglutide is GLP1R. Albiglutide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%albiglutide%" OR LOWER(tradeNames_string) LIKE "%albiglutide%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_1615', 'drugName': 'Albiglutide', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'GLP1R (ENSG00000112164)', 'yearOfFirstApproval': 2014, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1864 | Q59 | What is the genetic target of the small molecule drug Vortioxetine, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Vortioxetine: HTR1A, SLC6A4, and HTR3A. Vortioxetine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%vortioxetine%" OR LOWER(tradeNames_string) LIKE "%vortioxetine%" OR ... | [{'UUID': 'DrugGeneTargets_v2_778', 'drugName': 'Vortioxetine Hydrobromide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A4 (ENSG00000108576), HTR3A (ENSG00000166736), HTR1A (ENSG00000178394)', 'yearOfFirstApproval': 2013, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGen... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1725 | Q59 | What is the genetic target of the small molecule drug Parecoxib, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Parecoxib is PTGS2. Parecoxib reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%parecoxib%" OR LOWER(tradeNames_string) LIKE "%parecoxib%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_2672', 'drugName': 'Parecoxib Sodium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGS2 (ENSG00000073756)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_5993', 'drugName': 'Parecoxib', 'drugMolecularType... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1885 | Q59 | What is the genetic target of the small molecule drug Arformoterol Tartrate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Arformoterol Tartrate is ADRB2. Arformoterol Tartrate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%arformoterol tartrate%" OR LOWER(tradeNames_string) LIKE "%arformote... | [{'UUID': 'DrugGeneTargets_v2_440', 'drugName': 'Arformoterol Tartrate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRB2 (ENSG00000169252)', 'yearOfFirstApproval': 2006, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.853 | Q59 | What is the genetic target of the small molecule drug Donepezil, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Donepezil is ACHE. Donepezil reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%donepezil%" OR LOWER(tradeNames_string) LIKE "%donepezil%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_795', 'drugName': 'Donepezil Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ACHE (ENSG00000087085)', 'yearOfFirstApproval': 1996, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4037', 'drugName': 'Donepezil', 'drugMolec... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.4 | Q59 | What is the genetic target of the protein drug Desmopressin Acetate, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the protein drug Desmopressin Acetate: AVPR2, AVPR1A, and AVPR1B. Desmopressin Acetate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%desmopressin acetate%" OR LOWER(tradeNames_string) LIKE "%desmopress... | [{'UUID': 'DrugGeneTargets_v2_2993', 'drugName': 'Desmopressin Acetate', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'AVPR2 (ENSG00000126895), AVPR1A (ENSG00000166148), AVPR1B (ENSG00000198049)', 'yearOfFirstApproval': 1978, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1569 | Q59 | What is the genetic target of the small molecule drug Aminoglutethimide, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Aminoglutethimide: CYP19A1 and CYP11A1. Aminoglutethimide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%aminoglutethimide%" OR LOWER(tradeNames_string) LIKE "%aminoglutethi... | [{'UUID': 'DrugGeneTargets_v2_2691', 'drugName': 'Aminoglutethimide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CYP19A1 (ENSG00000137869), CYP11A1 (ENSG00000140459)', 'yearOfFirstApproval': 1980, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2692', 'drugName'... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1461 | Q59 | What is the genetic target of the small molecule drug Diphemanil Methylsulfate, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Diphemanil Methylsulfate: CHRM3 and CHRM1. Diphemanil Methylsulfate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%diphemanil methylsulfate%" OR LOWER(tradeNames_string) LIKE "%diphem... | [{'UUID': 'DrugGeneTargets_v2_1327', 'drugName': 'Diphemanil Methylsulfate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRM3 (ENSG00000133019), CHRM1 (ENSG00000168539)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1328', 'drugNa... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.473 | Q59 | What is the genetic target of the small molecule drug Eltrombopag, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Eltrombopag is MPL. Eltrombopag reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%eltrombopag%" OR LOWER(tradeNames_string) LIKE "%eltrombopag%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_2769', 'drugName': 'Eltrombopag Olamine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'MPL (ENSG00000117400)', 'yearOfFirstApproval': 2008, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1104', 'drugName': 'Eltrombopag', 'drugMolecul... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.325 | Q59 | What is the genetic target of the small molecule drug Samidorphan L-Malate, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Samidorphan L-Malate: OPRK1, OPRM1, and OPRD1. Samidorphan L-Malate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%samidorphan l-malate%" OR LOWER(tradeNames_string) LIKE "%samidorpha... | [{'UUID': 'DrugGeneTargets_v2_2889', 'drugName': 'Samidorphan L-Malate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'OPRK1 (ENSG00000082556), OPRM1 (ENSG00000112038), OPRD1 (ENSG00000116329)', 'yearOfFirstApproval': 2021, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTarg... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.6 | Q59 | What is the genetic target of the small molecule drug Alectinib, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Alectinib: ALK, RET, and EML4. Alectinib reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%alectinib%" OR LOWER(tradeNames_string) LIKE "%alectinib%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_1251', 'drugName': 'Alectinib Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ALK (ENSG00000171094), RET (ENSG00000165731), EML4 (ENSG00000143924)', 'yearOfFirstApproval': 2015, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTarget... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.225 | Q59 | What is the genetic target of the small molecule drug Azd8683, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Azd8683 is CHRM3. Azd8683 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%azd8683%" OR LOWER(tradeNames_string) LIKE "%azd8683%" OR LOWER(drug... | [{'UUID': 'DrugGeneTargets_v2_3899', 'drugName': 'Azd8683', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRM3 (ENSG00000133019)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1376 | Q59 | What is the genetic target of the antibody drug Sarilumab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Sarilumab is IL6R. Sarilumab reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%sarilumab%" OR LOWER(tradeNames_string) LIKE "%sarilumab%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_3005', 'drugName': 'Sarilumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'IL6R (ENSG00000160712)', 'yearOfFirstApproval': 2017, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.553 | Q59 | What is the genetic target of the small molecule drug Triflupromazine Hydrochloride, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Triflupromazine Hydrochloride is DRD2. Triflupromazine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%triflupromazine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%t... | [{'UUID': 'DrugGeneTargets_v2_4009', 'drugName': 'Triflupromazine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DRD2 (ENSG00000149295)', 'yearOfFirstApproval': 1957, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.231 | Q59 | What is the genetic target of the small molecule drug Grc-17536, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Grc-17536 is TRPA1. Grc-17536 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%grc-17536%" OR LOWER(tradeNames_string) LIKE "%grc-17536%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_5484', 'drugName': 'Grc-17536', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TRPA1 (ENSG00000104321)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.40 | Q59 | What is the genetic target of the small molecule drug Riociguat, and what is its status in clinical trials and FDA approval? | There are 4 genetic targets of the small molecule drug Riociguat: GUCY1B1, GUCY1B2, GUCY1A2, and GUCY1A1. Riociguat reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%riociguat%" OR LOWER(tradeNames_string) LIKE "%riociguat%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_3991', 'drugName': 'Riociguat', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'GUCY1B1 (ENSG00000061918), GUCY1B2 (ENSG00000123201), GUCY1A2 (ENSG00000152402), GUCY1A1 (ENSG00000164116)', 'yearOfFirstApproval': 2013, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.548 | Q59 | What is the genetic target of the oligonucleotide drug Oblimersen, and what is its status in clinical trials and FDA approval? | The genetic target of the oligonucleotide drug Oblimersen is BCL2. Oblimersen reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%oblimersen%" OR LOWER(tradeNames_string) LIKE "%oblimersen%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_5823', 'drugName': 'Oblimersen Sodium', 'drugMolecularType': 'Oligonucleotide', 'newLinkedTargets_string': 'BCL2 (ENSG00000171791)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_5570', 'drugName': 'Oblimersen', 'drugMolecularT... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.245 | Q59 | What is the genetic target of the antibody drug Ramucirumab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Ramucirumab is KDR. Ramucirumab reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ramucirumab%" OR LOWER(tradeNames_string) LIKE "%ramucirumab%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_1170', 'drugName': 'Ramucirumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'KDR (ENSG00000128052)', 'yearOfFirstApproval': 2014, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.905 | Q59 | What is the genetic target of the small molecule drug Dextromoramide, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Dextromoramide: OPRK1, OPRD1, and OPRM1. Dextromoramide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%dextromoramide%" OR LOWER(tradeNames_string) LIKE "%dextromoramide%"... | [{'UUID': 'DrugGeneTargets_v2_2904', 'drugName': 'Dextromoramide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'OPRK1 (ENSG00000082556), OPRD1 (ENSG00000116329), OPRM1 (ENSG00000112038)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1429 | Q59 | What is the genetic target of the oligonucleotide drug Viltolarsen, and what is its status in clinical trials and FDA approval? | The genetic target of the oligonucleotide drug Viltolarsen is DMD. Viltolarsen reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%viltolarsen%" OR LOWER(tradeNames_string) LIKE "%viltolarsen%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_2014', 'drugName': 'Viltolarsen', 'drugMolecularType': 'Oligonucleotide', 'newLinkedTargets_string': 'DMD (ENSG00000198947)', 'yearOfFirstApproval': 2020, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.139 | Q59 | What is the genetic target of the small molecule drug Rolofylline, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Rolofylline is ADORA1. Rolofylline reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%rolofylline%" OR LOWER(tradeNames_string) LIKE "%rolofylline%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_1264', 'drugName': 'Rolofylline', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADORA1 (ENSG00000163485)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1191 | Q59 | What is the genetic target of the small molecule drug Neramexane, and what is its status in clinical trials and FDA approval? | There are 9 genetic targets of the small molecule drug Neramexane: GRIN1, GRIN2A, GRIN2B, GRIN2D, GRIN3B, GRIN2C, GRIN3A, CHRNA9, and CHRNA10. Neramexane reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%neramexane%" OR LOWER(tradeNames_string) LIKE "%neramexane%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_3405', 'drugName': 'Neramexane', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'GRIN1 (ENSG00000176884), GRIN2A (ENSG00000183454), GRIN2B (ENSG00000273079), GRIN2D (ENSG00000105464), GRIN3B (ENSG00000116032), GRIN2C (ENSG00000161509), GRIN3A (ENSG00000198785), CHRNA9 (E... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1757 | Q59 | What is the genetic target of the small molecule drug Resmetirom, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Resmetirom is THRB. Resmetirom reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%resmetirom%" OR LOWER(tradeNames_string) LIKE "%resmetirom%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_3851', 'drugName': 'Resmetirom', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'THRB (ENSG00000151090)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1573 | Q59 | What is the genetic target of the protein drug Bremelanotide, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Bremelanotide is MC4R. Bremelanotide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%bremelanotide%" OR LOWER(tradeNames_string) LIKE "%bremelanotide%" O... | [{'UUID': 'DrugGeneTargets_v2_177', 'drugName': 'Bremelanotide Acetate', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'MC4R (ENSG00000166603)', 'yearOfFirstApproval': 2019, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4990', 'drugName': 'Bremelanotide', 'drugMolecularT... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1443 | Q59 | What is the genetic target of the small molecule drug Edralbrutinib, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Edralbrutinib is BTK. Edralbrutinib reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%edralbrutinib%" OR LOWER(tradeNames_string) LIKE "%edralbrutinib%" O... | [{'UUID': 'DrugGeneTargets_v2_242', 'drugName': 'Edralbrutinib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'BTK (ENSG00000010671)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.836 | Q59 | What is the genetic target of the small molecule drug Propiomazine Hydrochloride, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Propiomazine Hydrochloride is HRH1. Propiomazine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%propiomazine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%prop... | [{'UUID': 'DrugGeneTargets_v2_3422', 'drugName': 'Propiomazine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH1 (ENSG00000196639)', 'yearOfFirstApproval': 1960, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.451 | Q59 | What is the genetic target of the small molecule drug Triprolidine, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Triprolidine is HRH1. Triprolidine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%triprolidine%" OR LOWER(tradeNames_string) LIKE "%triprolidine%" OR ... | [{'UUID': 'DrugGeneTargets_v2_2151', 'drugName': 'Triprolidine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH1 (ENSG00000196639)', 'yearOfFirstApproval': 1983, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4462', 'drugName': 'Triprolidine', 'dr... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.849 | Q59 | What is the genetic target of the small molecule drug Prochlorperazine Edisylate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Prochlorperazine Edisylate is DRD2. Prochlorperazine Edisylate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%prochlorperazine edisylate%" OR LOWER(tradeNames_string) LIKE "%proc... | [{'UUID': 'DrugGeneTargets_v2_3536', 'drugName': 'Prochlorperazine Edisylate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DRD2 (ENSG00000149295)', 'yearOfFirstApproval': 1957, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1087 | Q59 | What is the genetic target of the small molecule drug Antazoline Phosphate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Antazoline Phosphate is HRH1. Antazoline Phosphate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%antazoline phosphate%" OR LOWER(tradeNames_string) LIKE "%antazoline... | [{'UUID': 'DrugGeneTargets_v2_4047', 'drugName': 'Antazoline Phosphate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH1 (ENSG00000196639)', 'yearOfFirstApproval': 1994, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1420 | Q59 | What is the genetic target of the small molecule drug Diethylstilbestrol Diphosphate, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Diethylstilbestrol Diphosphate: ESR2 and ESR1. Diethylstilbestrol Diphosphate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%diethylstilbestrol diphosphate%" OR LOWER(tradeNames_string) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_4127', 'drugName': 'Diethylstilbestrol Diphosphate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ESR2 (ENSG00000140009), ESR1 (ENSG00000091831)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1154 | Q59 | What is the genetic target of the small molecule drug Marimastat, and what is its status in clinical trials and FDA approval? | There are 6 genetic targets of the small molecule drug Marimastat: MMP9, MMP3, MMP7, MMP1, MMP2, and MMP12. Marimastat reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%marimastat%" OR LOWER(tradeNames_string) LIKE "%marimastat%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_5864', 'drugName': 'Marimastat', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'MMP9 (ENSG00000100985), MMP3 (ENSG00000149968), MMP7 (ENSG00000137673), MMP1 (ENSG00000196611), MMP2 (ENSG00000087245), MMP12 (ENSG00000262406)', 'yearOfFirstApproval': 0, 'maxClinicalTrialP... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1826 | Q59 | What is the genetic target of the small molecule drug Mycophenolate Mofetil Hydrochloride, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Mycophenolate Mofetil Hydrochloride: IMPDH1 and IMPDH2. Mycophenolate Mofetil Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%mycophenolate mofetil hydrochloride%" OR LOWER(tradeNames_string) LI... | [{'UUID': 'DrugGeneTargets_v2_4489', 'drugName': 'Mycophenolate Mofetil Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'IMPDH1 (ENSG00000106348), IMPDH2 (ENSG00000178035)', 'yearOfFirstApproval': 1998, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.588 | Q59 | What is the genetic target of the antibody drug Temelimab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Temelimab is ERVW-1. Temelimab reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%temelimab%" OR LOWER(tradeNames_string) LIKE "%temelimab%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_1980', 'drugName': 'Temelimab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'ERVW-1 (ENSG00000242950)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1892 | Q59 | What is the genetic target of the small molecule drug Alfuzosin Hydrochloride, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Alfuzosin Hydrochloride: ADRA1A, ADRA1D, and ADRA1B. Alfuzosin Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%alfuzosin hydrochloride%" OR LOWER(tradeNames_string) LIKE "%alfuzos... | [{'UUID': 'DrugGeneTargets_v2_1235', 'drugName': 'Alfuzosin Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRA1A (ENSG00000120907), ADRA1D (ENSG00000171873), ADRA1B (ENSG00000170214)', 'yearOfFirstApproval': 2003, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1970 | Q59 | What is the genetic target of the small molecule drug Paliperidone Palmitate, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Paliperidone Palmitate: DRD2 and HTR2A. Paliperidone Palmitate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%paliperidone palmitate%" OR LOWER(tradeNames_string) LIKE "%paliperi... | [{'UUID': 'DrugGeneTargets_v2_5388', 'drugName': 'Paliperidone Palmitate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DRD2 (ENSG00000149295), HTR2A (ENSG00000102468)', 'yearOfFirstApproval': 2009, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_5389', 'drugName'... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.668 | Q59 | What is the genetic target of the small molecule drug Eprotirome, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Eprotirome is THRB. Eprotirome reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%eprotirome%" OR LOWER(tradeNames_string) LIKE "%eprotirome%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_1020', 'drugName': 'Eprotirome', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'THRB (ENSG00000151090)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.442 | Q59 | What is the genetic target of the small molecule drug Pemetrexed Tromethamine, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Pemetrexed Tromethamine: DHFR and GART. Pemetrexed Tromethamine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%pemetrexed tromethamine%" OR LOWER(tradeNames_string) LIKE "%pemetre... | [{'UUID': 'DrugGeneTargets_v2_1187', 'drugName': 'Pemetrexed Tromethamine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DHFR (ENSG00000228716), GART (ENSG00000159131)', 'yearOfFirstApproval': 2022, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1188', 'drugName'... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1857 | Q59 | What is the genetic target of the small molecule drug Tamoxifen Citrate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Tamoxifen Citrate is ESR1. Tamoxifen Citrate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tamoxifen citrate%" OR LOWER(tradeNames_string) LIKE "%tamoxifen cit... | [{'UUID': 'DrugGeneTargets_v2_5201', 'drugName': 'Tamoxifen Citrate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ESR1 (ENSG00000091831)', 'yearOfFirstApproval': 1977, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.382 | Q59 | What is the genetic target of the small molecule drug Celecoxib, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Celecoxib is PTGS2. Celecoxib reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%celecoxib%" OR LOWER(tradeNames_string) LIKE "%celecoxib%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_5116', 'drugName': 'Celecoxib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGS2 (ENSG00000073756)', 'yearOfFirstApproval': 1998, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1478 | Q59 | What is the genetic target of the small molecule drug Sgx-523, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Sgx-523 is MET. Sgx-523 reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%sgx-523%" OR LOWER(tradeNames_string) LIKE "%sgx-523%" OR LOWER(drug... | [{'UUID': 'DrugGeneTargets_v2_438', 'drugName': 'Sgx-523', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'MET (ENSG00000105976)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.974 | Q59 | What is the genetic target of the small molecule drug Sitaxentan, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Sitaxentan: EDNRB and EDNRA. Sitaxentan reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%sitaxentan%" OR LOWER(tradeNames_string) LIKE "%sitaxentan%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_1670', 'drugName': 'Sitaxentan', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'EDNRB (ENSG00000136160), EDNRA (ENSG00000151617)', 'yearOfFirstApproval': 2006, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_5500', 'drugName': 'Sitaxent... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1210 | Q59 | What is the genetic target of the small molecule drug Ar-67, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Ar-67 is TOP1. Ar-67 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ar-67%" OR LOWER(tradeNames_string) LIKE "%ar-67%" OR LOWER(drugSyno... | [{'UUID': 'DrugGeneTargets_v2_1067', 'drugName': 'Ar-67', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TOP1 (ENSG00000198900)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.318 | Q59 | What is the genetic target of the small molecule drug Telcagepant, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Telcagepant is CALCRL. Telcagepant reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%telcagepant%" OR LOWER(tradeNames_string) LIKE "%telcagepant%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_2002', 'drugName': 'Telcagepant', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CALCRL (ENSG00000064989)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.698 | Q59 | What is the genetic target of the small molecule drug Balsalazide, and what is its status in clinical trials and FDA approval? | There are 4 genetic targets of the small molecule drug Balsalazide: PPARG, PTGS2, PTGS1, and ALOX5. Balsalazide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%balsalazide%" OR LOWER(tradeNames_string) LIKE "%balsalazide%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_1298', 'drugName': 'Balsalazide Disodium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PPARG (ENSG00000132170), PTGS2 (ENSG00000073756), PTGS1 (ENSG00000095303), ALOX5 (ENSG00000012779)', 'yearOfFirstApproval': 2000, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1505 | Q59 | What is the genetic target of the small molecule drug Atropine Sulfate, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Atropine Sulfate: CHRM1, CHRM3, and CHRM2. Atropine Sulfate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%atropine sulfate%" OR LOWER(tradeNames_string) LIKE "%atropine sulfa... | [{'UUID': 'DrugGeneTargets_v2_2047', 'drugName': 'Atropine Sulfate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRM1 (ENSG00000168539), CHRM3 (ENSG00000133019), CHRM2 (ENSG00000181072)', 'yearOfFirstApproval': 1960, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.430 | Q59 | What is the genetic target of the small molecule drug Apremilast, and what is its status in clinical trials and FDA approval? | There are 4 genetic targets of the small molecule drug Apremilast: PDE4A, PDE4D, PDE4B, and PDE4C. Apremilast reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%apremilast%" OR LOWER(tradeNames_string) LIKE "%apremilast%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_2487', 'drugName': 'Apremilast', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PDE4A (ENSG00000065989), PDE4D (ENSG00000113448), PDE4B (ENSG00000184588), PDE4C (ENSG00000105650)', 'yearOfFirstApproval': 2014, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.601 | Q59 | What is the genetic target of the small molecule drug Pamidronic Acid, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Pamidronic Acid is FDPS. Pamidronic Acid reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%pamidronic acid%" OR LOWER(tradeNames_string) LIKE "%pamidronic acid... | [{'UUID': 'DrugGeneTargets_v2_4461', 'drugName': 'Pamidronic Acid', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'FDPS (ENSG00000160752)', 'yearOfFirstApproval': 1991, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1964 | Q59 | What is the genetic target of the small molecule drug Methazolamide, and what is its status in clinical trials and FDA approval? | There are 4 genetic targets of the small molecule drug Methazolamide: CA1, CA2, CA7, and CA4. Methazolamide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%methazolamide%" OR LOWER(tradeNames_string) LIKE "%methazolamide%" O... | [{'UUID': 'DrugGeneTargets_v2_5021', 'drugName': 'Methazolamide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CA1 (ENSG00000133742), CA2 (ENSG00000104267), CA7 (ENSG00000168748), CA4 (ENSG00000167434)', 'yearOfFirstApproval': 1959, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'Dr... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.629 | Q59 | What is the genetic target of the small molecule drug Edrophonium Chloride, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Edrophonium Chloride is ACHE. Edrophonium Chloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%edrophonium chloride%" OR LOWER(tradeNames_string) LIKE "%edrophoniu... | [{'UUID': 'DrugGeneTargets_v2_5141', 'drugName': 'Edrophonium Chloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ACHE (ENSG00000087085)', 'yearOfFirstApproval': 1951, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1170 | Q59 | What is the genetic target of the small molecule drug Monomethyl Fumarate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Monomethyl Fumarate is KEAP1. Monomethyl Fumarate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%monomethyl fumarate%" OR LOWER(tradeNames_string) LIKE "%monomethyl ... | [{'UUID': 'DrugGeneTargets_v2_313', 'drugName': 'Monomethyl Fumarate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'KEAP1 (ENSG00000079999)', 'yearOfFirstApproval': 2020, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1254 | Q59 | What is the genetic target of the oligonucleotide drug Cenersen Sodium, and what is its status in clinical trials and FDA approval? | The genetic target of the oligonucleotide drug Cenersen Sodium is TP53. Cenersen Sodium reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%cenersen sodium%" OR LOWER(tradeNames_string) LIKE "%cenersen sodium... | [{'UUID': 'DrugGeneTargets_v2_444', 'drugName': 'Cenersen Sodium', 'drugMolecularType': 'Oligonucleotide', 'newLinkedTargets_string': 'TP53 (ENSG00000141510)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.230 | Q59 | What is the genetic target of the small molecule drug Methysergide, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Methysergide: HTR2C, HTR2B, and HTR1A. Methysergide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%methysergide%" OR LOWER(tradeNames_string) LIKE "%methysergide%" OR ... | [{'UUID': 'DrugGeneTargets_v2_2808', 'drugName': 'Methysergide Maleate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR2C (ENSG00000147246), HTR2B (ENSG00000135914), HTR1A (ENSG00000178394)', 'yearOfFirstApproval': 1962, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTarg... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1180 | Q59 | What is the genetic target of the small molecule drug Benzquinamide, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Benzquinamide is DRD2. Benzquinamide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%benzquinamide%" OR LOWER(tradeNames_string) LIKE "%benzquinamide%" O... | [{'UUID': 'DrugGeneTargets_v2_384', 'drugName': 'Benzquinamide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DRD2 (ENSG00000149295)', 'yearOfFirstApproval': 1974, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1440', 'drugName': 'Benzquinamide Hydrochloride', 'd... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1332 | Q59 | What is the genetic target of the small molecule drug Proglumide, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Proglumide: CCKBR and CCKAR. Proglumide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%proglumide%" OR LOWER(tradeNames_string) LIKE "%proglumide%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_5575', 'drugName': 'Proglumide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CCKBR (ENSG00000110148), CCKAR (ENSG00000163394)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1587 | Q59 | What is the genetic target of the small molecule drug Montelukast, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Montelukast is CYSLTR1. Montelukast reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%montelukast%" OR LOWER(tradeNames_string) LIKE "%montelukast%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_2453', 'drugName': 'Montelukast Sodium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CYSLTR1 (ENSG00000173198)', 'yearOfFirstApproval': 1998, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2189', 'drugName': 'Montelukast', 'drugMole... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.69 | Q59 | What is the genetic target of the small molecule drug Fluorometholone Acetate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Fluorometholone Acetate is NR3C1. Fluorometholone Acetate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%fluorometholone acetate%" OR LOWER(tradeNames_string) LIKE "%fluorom... | [{'UUID': 'DrugGeneTargets_v2_873', 'drugName': 'Fluorometholone Acetate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'NR3C1 (ENSG00000113580)', 'yearOfFirstApproval': 1986, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.25 | Q59 | What is the genetic target of the small molecule drug Sovleplenib, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Sovleplenib is SYK. Sovleplenib reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%sovleplenib%" OR LOWER(tradeNames_string) LIKE "%sovleplenib%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_3827', 'drugName': 'Sovleplenib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SYK (ENSG00000165025)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.147 | Q59 | What is the genetic target of the small molecule drug Digitoxin, and what is its status in clinical trials and FDA approval? | There are 8 genetic targets of the small molecule drug Digitoxin: ATP1A1, ATP1B2, ATP1B1, ATP1A2, ATP1B3, ATP1A3, ATP1A4, and FXYD2. Digitoxin reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%digitoxin%" OR LOWER(tradeNames_string) LIKE "%digitoxin%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_4877', 'drugName': 'Digitoxin', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ATP1A1 (ENSG00000163399), ATP1B2 (ENSG00000129244), ATP1B1 (ENSG00000143153), ATP1A2 (ENSG00000018625), ATP1B3 (ENSG00000069849), ATP1A3 (ENSG00000105409), ATP1A4 (ENSG00000132681), FXYD2 (EN... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.542 | Q59 | What is the genetic target of the small molecule drug Dexlansoprazole, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Dexlansoprazole: ATP4A and ATP4B. Dexlansoprazole reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%dexlansoprazole%" OR LOWER(tradeNames_string) LIKE "%dexlansoprazole... | [{'UUID': 'DrugGeneTargets_v2_908', 'drugName': 'Dexlansoprazole', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ATP4A (ENSG00000105675), ATP4B (ENSG00000186009)', 'yearOfFirstApproval': 2009, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.818 | Q59 | What is the genetic target of the small molecule drug Danicopan, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Danicopan is CFD. Danicopan reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%danicopan%" OR LOWER(tradeNames_string) LIKE "%danicopan%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_3017', 'drugName': 'Danicopan', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CFD (ENSG00000197766)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1120 | Q59 | What is the genetic target of the small molecule drug Naldemedine Tosylate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Naldemedine Tosylate is OPRM1. Naldemedine Tosylate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%naldemedine tosylate%" OR LOWER(tradeNames_string) LIKE "%naldemedin... | [{'UUID': 'DrugGeneTargets_v2_1003', 'drugName': 'Naldemedine Tosylate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'OPRM1 (ENSG00000112038)', 'yearOfFirstApproval': 2017, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.88 | Q59 | What is the genetic target of the small molecule drug Brexpiprazole, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Brexpiprazole: HTR2A, DRD2, and HTR1A. Brexpiprazole reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%brexpiprazole%" OR LOWER(tradeNames_string) LIKE "%brexpiprazole%" O... | [{'UUID': 'DrugGeneTargets_v2_6348', 'drugName': 'Brexpiprazole', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR2A (ENSG00000102468), DRD2 (ENSG00000149295), HTR1A (ENSG00000178394)', 'yearOfFirstApproval': 2015, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_6... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1183 | Q59 | What is the genetic target of the small molecule drug Alprostadil, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Alprostadil: PTGER2 and PTGER1. Alprostadil reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%alprostadil%" OR LOWER(tradeNames_string) LIKE "%alprostadil%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_4035', 'drugName': 'Alprostadil', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGER2 (ENSG00000125384), PTGER1 (ENSG00000160951)', 'yearOfFirstApproval': 1981, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4036', 'drugName': 'Alpro... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1333 | Q59 | What is the genetic target of the small molecule drug Ns-018, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Ns-018 is JAK2. Ns-018 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ns-018%" OR LOWER(tradeNames_string) LIKE "%ns-018%" OR LOWER(drugSy... | [{'UUID': 'DrugGeneTargets_v2_5451', 'drugName': 'Ns-018', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'JAK2 (ENSG00000096968)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1806 | Q59 | What is the genetic target of the small molecule drug Nelotanserin, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Nelotanserin is HTR2A. Nelotanserin reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%nelotanserin%" OR LOWER(tradeNames_string) LIKE "%nelotanserin%" OR ... | [{'UUID': 'DrugGeneTargets_v2_2036', 'drugName': 'Nelotanserin', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR2A (ENSG00000102468)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1819 | Q59 | What is the genetic target of the small molecule drug Disopyramide Phosphate, and what is its status in clinical trials and FDA approval? | There are 10 genetic targets of the small molecule drug Disopyramide Phosphate: SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. Disopyramide Phosphate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%disopyramide phosphate%" OR LOWER(tradeNames_string) LIKE "%disopyra... | [{'UUID': 'DrugGeneTargets_v2_6051', 'drugName': 'Disopyramide Phosphate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SCN1A (ENSG00000144285), SCN5A (ENSG00000183873), SCN4A (ENSG00000007314), SCN7A (ENSG00000136546), SCN2A (ENSG00000136531), SCN9A (ENSG00000169432), SCN3A (ENSG00000153253), SCN... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1374 | Q59 | What is the genetic target of the antibody drug Tafasitamab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Tafasitamab is CD19. Tafasitamab reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tafasitamab%" OR LOWER(tradeNames_string) LIKE "%tafasitamab%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_3753', 'drugName': 'Tafasitamab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'CD19 (ENSG00000177455)', 'yearOfFirstApproval': 2020, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1144 | Q59 | What is the genetic target of the small molecule drug Valproate Sodium, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Valproate Sodium is ALDH5A1. Valproate Sodium reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%valproate sodium%" OR LOWER(tradeNames_string) LIKE "%valproate sodi... | [{'UUID': 'DrugGeneTargets_v2_1604', 'drugName': 'Valproate Sodium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ALDH5A1 (ENSG00000112294)', 'yearOfFirstApproval': 1996, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.367 | Q59 | What is the genetic target of the small molecule drug Mk-0767, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Mk-0767: PPARA and PPARG. Mk-0767 reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%mk-0767%" OR LOWER(tradeNames_string) LIKE "%mk-0767%" OR LOWER(drug... | [{'UUID': 'DrugGeneTargets_v2_6202', 'drugName': 'Mk-0767', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PPARA (ENSG00000186951), PPARG (ENSG00000132170)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_6203', 'drugName': 'Mk-0767', 'dr... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1790 | Q59 | What is the genetic target of the antibody drug Adalimumab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Adalimumab is TNF. Adalimumab reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%adalimumab%" OR LOWER(tradeNames_string) LIKE "%adalimumab%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_3802', 'drugName': 'Adalimumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'TNF (ENSG00000232810)', 'yearOfFirstApproval': 2002, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1208 | Q59 | What is the genetic target of the small molecule drug Omidenepag Isopropyl, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Omidenepag Isopropyl is PTGER2. Omidenepag Isopropyl reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%omidenepag isopropyl%" OR LOWER(tradeNames_string) LIKE "%omidenepag... | [{'UUID': 'DrugGeneTargets_v2_2182', 'drugName': 'Omidenepag Isopropyl', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGER2 (ENSG00000125384)', 'yearOfFirstApproval': 2022, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1035 | Q59 | What is the genetic target of the small molecule drug Sulfinpyrazone, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Sulfinpyrazone is SLC22A12. Sulfinpyrazone reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%sulfinpyrazone%" OR LOWER(tradeNames_string) LIKE "%sulfinpyrazone%"... | [{'UUID': 'DrugGeneTargets_v2_378', 'drugName': 'Sulfinpyrazone', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC22A12 (ENSG00000197891)', 'yearOfFirstApproval': 1959, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1039 | Q59 | What is the genetic target of the small molecule drug Becocalcidiol, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Becocalcidiol is VDR. Becocalcidiol reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%becocalcidiol%" OR LOWER(tradeNames_string) LIKE "%becocalcidiol%" O... | [{'UUID': 'DrugGeneTargets_v2_5125', 'drugName': 'Becocalcidiol', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'VDR (ENSG00000111424)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1761 | Q59 | What is the genetic target of the small molecule drug Tofacitinib Citrate, and what is its status in clinical trials and FDA approval? | There are 4 genetic targets of the small molecule drug Tofacitinib Citrate: JAK3, JAK1, JAK2, and TYK2. Tofacitinib Citrate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tofacitinib citrate%" OR LOWER(tradeNames_string) LIKE "%tofacitinib... | [{'UUID': 'DrugGeneTargets_v2_3515', 'drugName': 'Tofacitinib Citrate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'JAK3 (ENSG00000105639), JAK1 (ENSG00000162434), JAK2 (ENSG00000096968), TYK2 (ENSG00000105397)', 'yearOfFirstApproval': 2012, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1357 | Q59 | What is the genetic target of the small molecule drug Paliperidone, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Paliperidone: DRD2 and HTR2A. Paliperidone reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%paliperidone%" OR LOWER(tradeNames_string) LIKE "%paliperidone%" OR ... | [{'UUID': 'DrugGeneTargets_v2_3644', 'drugName': 'Paliperidone', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DRD2 (ENSG00000149295), HTR2A (ENSG00000102468)', 'yearOfFirstApproval': 2006, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3643', 'drugName': 'Paliper... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1875 | Q59 | What is the genetic target of the small molecule drug Ezetimibe, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Ezetimibe is NPC1L1. Ezetimibe reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ezetimibe%" OR LOWER(tradeNames_string) LIKE "%ezetimibe%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_4425', 'drugName': 'Ezetimibe', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'NPC1L1 (ENSG00000015520)', 'yearOfFirstApproval': 2002, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.672 | Q59 | What is the genetic target of the small molecule drug Fonadelpar, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Fonadelpar is PPARD. Fonadelpar reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%fonadelpar%" OR LOWER(tradeNames_string) LIKE "%fonadelpar%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_2940', 'drugName': 'Fonadelpar', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PPARD (ENSG00000112033)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.369 | Q59 | What is the genetic target of the small molecule drug Stanozolol, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Stanozolol is AR. Stanozolol reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%stanozolol%" OR LOWER(tradeNames_string) LIKE "%stanozolol%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_5791', 'drugName': 'Stanozolol', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'AR (ENSG00000169083)', 'yearOfFirstApproval': 1962, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.80 | Q59 | What is the genetic target of the small molecule drug Daprodustat, and what is its status in clinical trials and FDA approval? | There are 4 genetic targets of the small molecule drug Daprodustat: EGLN2, P4HTM, EGLN1, and EGLN3. Daprodustat reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%daprodustat%" OR LOWER(tradeNames_string) LIKE "%daprodustat%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_2677', 'drugName': 'Daprodustat', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'EGLN2 (ENSG00000269858), P4HTM (ENSG00000178467), EGLN1 (ENSG00000135766), EGLN3 (ENSG00000129521)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.28 | Q59 | What is the genetic target of the small molecule drug Amineptine, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Amineptine: DRD2 and DRD1. Amineptine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%amineptine%" OR LOWER(tradeNames_string) LIKE "%amineptine%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_2419', 'drugName': 'Amineptine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DRD2 (ENSG00000149295), DRD1 (ENSG00000184845)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1438 | Q59 | What is the genetic target of the protein drug Teduglutide, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Teduglutide is GLP2R. Teduglutide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%teduglutide%" OR LOWER(tradeNames_string) LIKE "%teduglutide%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_1614', 'drugName': 'Teduglutide', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'GLP2R (ENSG00000065325)', 'yearOfFirstApproval': 2012, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.531 | Q59 | What is the genetic target of the small molecule drug Hydroxyzine Pamoate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Hydroxyzine Pamoate is HRH1. Hydroxyzine Pamoate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%hydroxyzine pamoate%" OR LOWER(tradeNames_string) LIKE "%hydroxyzine... | [{'UUID': 'DrugGeneTargets_v2_1501', 'drugName': 'Hydroxyzine Pamoate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH1 (ENSG00000196639)', 'yearOfFirstApproval': 1959, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1836 | Q59 | What is the genetic target of the small molecule drug Methdilazine, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Methdilazine is HRH1. Methdilazine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%methdilazine%" OR LOWER(tradeNames_string) LIKE "%methdilazine%" OR ... | [{'UUID': 'DrugGeneTargets_v2_2195', 'drugName': 'Methdilazine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH1 (ENSG00000196639)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_6240', 'drugName': 'Methdilazine Hydrochloride', 'dr... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.56 | Q59 | What is the genetic target of the antibody drug Lebrikizumab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Lebrikizumab is IL13. Lebrikizumab reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%lebrikizumab%" OR LOWER(tradeNames_string) LIKE "%lebrikizumab%" OR ... | [{'UUID': 'DrugGeneTargets_v2_2381', 'drugName': 'Lebrikizumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'IL13 (ENSG00000169194)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.645 | Q59 | What is the genetic target of the antibody drug Imsidolimab, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the antibody drug Imsidolimab: IL1RL2 and IL1RAP. Imsidolimab reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%imsidolimab%" OR LOWER(tradeNames_string) LIKE "%imsidolimab%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_102', 'drugName': 'Imsidolimab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'IL1RL2 (ENSG00000115598), IL1RAP (ENSG00000196083)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.306 | Q59 | What is the genetic target of the small molecule drug Enmd-2076, and what is its status in clinical trials and FDA approval? | There are 7 genetic targets of the small molecule drug Enmd-2076: KIT, KDR, FLT3, FGFR3, AURKB, CSF1R, and AURKA. Enmd-2076 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%enmd-2076%" OR LOWER(tradeNames_string) LIKE "%enmd-2076%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_5432', 'drugName': 'Enmd-2076', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'KIT (ENSG00000157404), KDR (ENSG00000128052), FLT3 (ENSG00000122025), FGFR3 (ENSG00000068078), AURKB (ENSG00000178999), CSF1R (ENSG00000182578), AURKA (ENSG00000087586)', 'yearOfFirstApproval... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.725 | Q59 | What is the genetic target of the small molecule drug Dexmethylphenidate, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Dexmethylphenidate: SLC6A2 and SLC6A3. Dexmethylphenidate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%dexmethylphenidate%" OR LOWER(tradeNames_string) LIKE "%dexmethylphe... | [{'UUID': 'DrugGeneTargets_v2_2117', 'drugName': 'Serdexmethylphenidate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A3 (ENSG00000142319), SLC6A2 (ENSG00000103546)', 'yearOfFirstApproval': 2021, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4161', 'drugNam... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.631 | Q59 | What is the genetic target of the small molecule drug Carbidopa, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Carbidopa is DDC. Carbidopa reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%carbidopa%" OR LOWER(tradeNames_string) LIKE "%carbidopa%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_3213', 'drugName': 'Carbidopa', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DDC (ENSG00000132437)', 'yearOfFirstApproval': 1975, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4465', 'drugName': 'Carbidopa', 'drugMolecularType': 'Sm... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.8 | Q59 | What is the genetic target of the small molecule drug Ph-797804, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Ph-797804 is MAPK14. Ph-797804 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ph-797804%" OR LOWER(tradeNames_string) LIKE "%ph-797804%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_4541', 'drugName': 'Ph-797804', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'MAPK14 (ENSG00000112062)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.810 | Q59 | What is the genetic target of the small molecule drug Asenapine Maleate, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Asenapine Maleate: HTR2A and DRD2. Asenapine Maleate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%asenapine maleate%" OR LOWER(tradeNames_string) LIKE "%asenapine mal... | [{'UUID': 'DrugGeneTargets_v2_4103', 'drugName': 'Asenapine Maleate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR2A (ENSG00000102468), DRD2 (ENSG00000149295)', 'yearOfFirstApproval': 2009, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4104', 'drugName': 'As... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.