uuid stringlengths 4 8 | template_uuid stringclasses 40
values | question stringlengths 13 193 | answer stringlengths 29 2.2k | benchmark_query stringlengths 133 622 | execution_results stringlengths 2 1.14M | query_type stringclasses 2
values | sql_category stringclasses 26
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Q59.1058 | Q59 | What is the genetic target of the antibody drug Zimberelimab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Zimberelimab is PDCD1. Zimberelimab reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%zimberelimab%" OR LOWER(tradeNames_string) LIKE "%zimberelimab%" OR ... | [{'UUID': 'DrugGeneTargets_v2_2231', 'drugName': 'Zimberelimab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'PDCD1 (ENSG00000188389)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.340 | Q59 | What is the genetic target of the antibody drug Bepranemab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Bepranemab is MAPT. Bepranemab reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%bepranemab%" OR LOWER(tradeNames_string) LIKE "%bepranemab%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_3673', 'drugName': 'Bepranemab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'MAPT (ENSG00000186868)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.48 | Q59 | What is the genetic target of the small molecule drug Decamethonium Bromide, and what is its status in clinical trials and FDA approval? | There are 5 genetic targets of the small molecule drug Decamethonium Bromide: CHRNA1, CHRNG, CHRNB1, CHRND, and CHRNE. Decamethonium Bromide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%decamethonium bromide%" OR LOWER(tradeNames_string) LIKE "%decametho... | [{'UUID': 'DrugGeneTargets_v2_5170', 'drugName': 'Decamethonium Bromide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRNA1 (ENSG00000138435), CHRNG (ENSG00000196811), CHRNB1 (ENSG00000170175), CHRND (ENSG00000135902), CHRNE (ENSG00000108556)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1481 | Q59 | What is the genetic target of the small molecule drug Alogliptin, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Alogliptin is DPP4. Alogliptin reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%alogliptin%" OR LOWER(tradeNames_string) LIKE "%alogliptin%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_6386', 'drugName': 'Alogliptin', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DPP4 (ENSG00000197635)', 'yearOfFirstApproval': 2013, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2469', 'drugName': 'Alogliptin Benzoate', 'drugMolecul... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.109 | Q59 | What is the genetic target of the oligonucleotide drug Patisiran, and what is its status in clinical trials and FDA approval? | The genetic target of the oligonucleotide drug Patisiran is TTR. Patisiran reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%patisiran%" OR LOWER(tradeNames_string) LIKE "%patisiran%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_4793', 'drugName': 'Patisiran', 'drugMolecularType': 'Oligonucleotide', 'newLinkedTargets_string': 'TTR (ENSG00000118271)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2512', 'drugName': 'Patisiran Sodium', 'drugMolecularType'... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.353 | Q59 | What is the genetic target of the small molecule drug Cetirizine, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Cetirizine is HRH1. Cetirizine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%cetirizine%" OR LOWER(tradeNames_string) LIKE "%cetirizine%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_2101', 'drugName': 'Cetirizine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH1 (ENSG00000196639)', 'yearOfFirstApproval': 1995, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_6377', 'drugName': 'Cetirizine Hydrochloride', 'drugMo... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.241 | Q59 | What is the genetic target of the protein drug Follitropin Alfa, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Follitropin Alfa is FSHR. Follitropin Alfa reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%follitropin alfa%" OR LOWER(tradeNames_string) LIKE "%follitropin al... | [{'UUID': 'DrugGeneTargets_v2_2306', 'drugName': 'Corifollitropin Alfa', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'FSHR (ENSG00000170820)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_206', 'drugName': 'Follitropin Alfa', 'drugMolecularTy... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.216 | Q59 | What is the genetic target of the small molecule drug Turofexorate Isopropyl, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Turofexorate Isopropyl is NR1H4. Turofexorate Isopropyl reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%turofexorate isopropyl%" OR LOWER(tradeNames_string) LIKE "%turofexo... | [{'UUID': 'DrugGeneTargets_v2_4186', 'drugName': 'Turofexorate Isopropyl', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'NR1H4 (ENSG00000012504)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1827 | Q59 | What is the genetic target of the small molecule drug Remoxipride Hydrochloride, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Remoxipride Hydrochloride is DRD2. Remoxipride Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%remoxipride hydrochloride%" OR LOWER(tradeNames_string) LIKE "%remox... | [{'UUID': 'DrugGeneTargets_v2_3071', 'drugName': 'Remoxipride Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DRD2 (ENSG00000149295)', 'yearOfFirstApproval': 1990, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1138 | Q59 | What is the genetic target of the small molecule drug Sacubitril, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Sacubitril is MME. Sacubitril reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%sacubitril%" OR LOWER(tradeNames_string) LIKE "%sacubitril%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_1487', 'drugName': 'Sacubitril', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'MME (ENSG00000196549)', 'yearOfFirstApproval': 2015, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.800 | Q59 | What is the genetic target of the protein drug Luspatercept, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the protein drug Luspatercept: TGFB1, TGFB2, and TGFB3. Luspatercept reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%luspatercept%" OR LOWER(tradeNames_string) LIKE "%luspatercept%" OR ... | [{'UUID': 'DrugGeneTargets_v2_6093', 'drugName': 'Luspatercept', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'TGFB1 (ENSG00000105329), TGFB2 (ENSG00000092969), TGFB3 (ENSG00000119699)', 'yearOfFirstApproval': 2019, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1123 | Q59 | What is the genetic target of the small molecule drug Bupivacaine Hydrochloride, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Bupivacaine Hydrochloride is SCN4A. Bupivacaine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%bupivacaine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%bupiv... | [{'UUID': 'DrugGeneTargets_v2_1687', 'drugName': 'Bupivacaine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SCN4A (ENSG00000007314)', 'yearOfFirstApproval': 1972, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4768', 'drugName': 'Levobupivacaine Hy... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1583 | Q59 | What is the genetic target of the small molecule drug Gemfibrozil, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Gemfibrozil is PPARA. Gemfibrozil reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%gemfibrozil%" OR LOWER(tradeNames_string) LIKE "%gemfibrozil%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_6015', 'drugName': 'Gemfibrozil', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PPARA (ENSG00000186951)', 'yearOfFirstApproval': 1981, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1672 | Q59 | What is the genetic target of the protein drug Calcitonin Human, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Calcitonin Human is CALCR. Calcitonin Human reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%calcitonin human%" OR LOWER(tradeNames_string) LIKE "%calcitonin hum... | [{'UUID': 'DrugGeneTargets_v2_1951', 'drugName': 'Calcitonin Human', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'CALCR (ENSG00000004948)', 'yearOfFirstApproval': 1986, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.529 | Q59 | What is the genetic target of the small molecule drug Tacrine, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Tacrine: BCHE and ACHE. Tacrine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tacrine%" OR LOWER(tradeNames_string) LIKE "%tacrine%" OR LOWER(drug... | [{'UUID': 'DrugGeneTargets_v2_2037', 'drugName': 'Tacrine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'BCHE (ENSG00000114200), ACHE (ENSG00000087085)', 'yearOfFirstApproval': 1993, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_6243', 'drugName': 'Tacrine Hydro... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.235 | Q59 | What is the genetic target of the small molecule drug Cimicoxib, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Cimicoxib is PTGS2. Cimicoxib reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%cimicoxib%" OR LOWER(tradeNames_string) LIKE "%cimicoxib%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_4452', 'drugName': 'Cimicoxib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGS2 (ENSG00000073756)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.651 | Q59 | What is the genetic target of the antibody drug Vilobelimab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Vilobelimab is C5. Vilobelimab reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%vilobelimab%" OR LOWER(tradeNames_string) LIKE "%vilobelimab%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_1024', 'drugName': 'Vilobelimab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'C5 (ENSG00000106804)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1509 | Q59 | What is the genetic target of the antibody drug Briakinumab, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the antibody drug Briakinumab: IL12B, IL23A, and IL12A. Briakinumab reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%briakinumab%" OR LOWER(tradeNames_string) LIKE "%briakinumab%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_1844', 'drugName': 'Briakinumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'IL12B (ENSG00000113302), IL23A (ENSG00000110944), IL12A (ENSG00000168811)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_1845', 'dr... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.539 | Q59 | What is the genetic target of the small molecule drug Fluoxetine Hydrochloride, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Fluoxetine Hydrochloride is SLC6A4. Fluoxetine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%fluoxetine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%fluoxe... | [{'UUID': 'DrugGeneTargets_v2_4711', 'drugName': 'Fluoxetine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A4 (ENSG00000108576)', 'yearOfFirstApproval': 1987, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1753 | Q59 | What is the genetic target of the small molecule drug Azd-7268, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Azd-7268 is OPRD1. Azd-7268 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%azd-7268%" OR LOWER(tradeNames_string) LIKE "%azd-7268%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_1019', 'drugName': 'Azd-7268', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'OPRD1 (ENSG00000116329)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.610 | Q59 | What is the genetic target of the small molecule drug Adc3680, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Adc3680 is PTGDR2. Adc3680 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%adc3680%" OR LOWER(tradeNames_string) LIKE "%adc3680%" OR LOWER(drug... | [{'UUID': 'DrugGeneTargets_v2_5282', 'drugName': 'Adc3680', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGDR2 (ENSG00000183134)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1780 | Q59 | What is the genetic target of the small molecule drug Loxoprofen, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Loxoprofen: PTGS2 and PTGS1. Loxoprofen reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%loxoprofen%" OR LOWER(tradeNames_string) LIKE "%loxoprofen%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_2702', 'drugName': 'Loxoprofen', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGS2 (ENSG00000073756), PTGS1 (ENSG00000095303)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1083 | Q59 | What is the genetic target of the small molecule drug Flumethasone Pivalate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Flumethasone Pivalate is NR3C1. Flumethasone Pivalate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%flumethasone pivalate%" OR LOWER(tradeNames_string) LIKE "%flumethas... | [{'UUID': 'DrugGeneTargets_v2_3762', 'drugName': 'Flumethasone Pivalate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'NR3C1 (ENSG00000113580)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1407 | Q59 | What is the genetic target of the small molecule drug Phenacemide, and what is its status in clinical trials and FDA approval? | There are 10 genetic targets of the small molecule drug Phenacemide: SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. Phenacemide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%phenacemide%" OR LOWER(tradeNames_string) LIKE "%phenacemide%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_6273', 'drugName': 'Phenacemide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SCN1A (ENSG00000144285), SCN5A (ENSG00000183873), SCN4A (ENSG00000007314), SCN7A (ENSG00000136546), SCN2A (ENSG00000136531), SCN9A (ENSG00000169432), SCN3A (ENSG00000153253), SCN11A (ENSG00... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.62 | Q59 | What is the genetic target of the small molecule drug Cisatracurium Besylate, and what is its status in clinical trials and FDA approval? | There are 5 genetic targets of the small molecule drug Cisatracurium Besylate: CHRNA1, CHRNG, CHRNB1, CHRND, and CHRNE. Cisatracurium Besylate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%cisatracurium besylate%" OR LOWER(tradeNames_string) LIKE "%cisatrac... | [{'UUID': 'DrugGeneTargets_v2_3676', 'drugName': 'Cisatracurium Besylate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRNA1 (ENSG00000138435), CHRNG (ENSG00000196811), CHRNB1 (ENSG00000170175), CHRND (ENSG00000135902), CHRNE (ENSG00000108556)', 'yearOfFirstApproval': 1995, 'maxClinicalTrialPhas... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1643 | Q59 | What is the genetic target of the small molecule drug Mirabegron, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Mirabegron is ADRB3. Mirabegron reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%mirabegron%" OR LOWER(tradeNames_string) LIKE "%mirabegron%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_1178', 'drugName': 'Mirabegron', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRB3 (ENSG00000188778)', 'yearOfFirstApproval': 2012, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.95 | Q59 | What is the genetic target of the small molecule drug Pevonedistat, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Pevonedistat: UBA3 and NAE1. Pevonedistat reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%pevonedistat%" OR LOWER(tradeNames_string) LIKE "%pevonedistat%" OR ... | [{'UUID': 'DrugGeneTargets_v2_3764', 'drugName': 'Pevonedistat', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'UBA3 (ENSG00000144744), NAE1 (ENSG00000159593)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.673 | Q59 | What is the genetic target of the small molecule drug Chenodiol, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Chenodiol is NR1H4. Chenodiol reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%chenodiol%" OR LOWER(tradeNames_string) LIKE "%chenodiol%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_976', 'drugName': 'Chenodiol', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'NR1H4 (ENSG00000012504)', 'yearOfFirstApproval': 1983, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.284 | Q59 | What is the genetic target of the small molecule drug Phentolamine Mesylate, and what is its status in clinical trials and FDA approval? | There are 6 genetic targets of the small molecule drug Phentolamine Mesylate: ADRA1A, ADRA2A, ADRA2C, ADRA1D, ADRA1B, and ADRA2B. Phentolamine Mesylate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%phentolamine mesylate%" OR LOWER(tradeNames_string) LIKE "%phentolam... | [{'UUID': 'DrugGeneTargets_v2_3568', 'drugName': 'Phentolamine Mesylate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRA1A (ENSG00000120907), ADRA2A (ENSG00000150594), ADRA2C (ENSG00000184160), ADRA1D (ENSG00000171873), ADRA1B (ENSG00000170214), ADRA2B (ENSG00000274286)', 'yearOfFirstApproval':... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1796 | Q59 | What is the genetic target of the protein drug Epoetin Delta, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Epoetin Delta is EPOR. Epoetin Delta reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%epoetin delta%" OR LOWER(tradeNames_string) LIKE "%epoetin delta%" O... | [{'UUID': 'DrugGeneTargets_v2_2704', 'drugName': 'Epoetin Delta', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'EPOR (ENSG00000187266)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.364 | Q59 | What is the genetic target of the small molecule drug Daridorexant, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Daridorexant: HCRTR1 and HCRTR2. Daridorexant reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%daridorexant%" OR LOWER(tradeNames_string) LIKE "%daridorexant%" OR ... | [{'UUID': 'DrugGeneTargets_v2_5696', 'drugName': 'Daridorexant Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HCRTR2 (ENSG00000137252), HCRTR1 (ENSG00000121764)', 'yearOfFirstApproval': 2022, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4411', 'dr... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1468 | Q59 | What is the genetic target of the small molecule drug Migalastat Hydrochloride, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Migalastat Hydrochloride is GLA. Migalastat Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%migalastat hydrochloride%" OR LOWER(tradeNames_string) LIKE "%migala... | [{'UUID': 'DrugGeneTargets_v2_549', 'drugName': 'Migalastat Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'GLA (ENSG00000102393)', 'yearOfFirstApproval': 2018, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1169 | Q59 | What is the genetic target of the antibody drug Faralimomab, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the antibody drug Faralimomab: IFNA1 and IFNA13. Faralimomab reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%faralimomab%" OR LOWER(tradeNames_string) LIKE "%faralimomab%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_928', 'drugName': 'Faralimomab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'IFNA1 (ENSG00000197919), IFNA13 (ENSG00000233816)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.854 | Q59 | What is the genetic target of the small molecule drug Tolbutamide, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Tolbutamide: KCNJ11 and ABCC8. Tolbutamide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tolbutamide%" OR LOWER(tradeNames_string) LIKE "%tolbutamide%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_427', 'drugName': 'Tolbutamide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'KCNJ11 (ENSG00000187486), ABCC8 (ENSG00000006071)', 'yearOfFirstApproval': 1961, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3569', 'drugName': 'Tolbuta... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1379 | Q59 | What is the genetic target of the small molecule drug Amrubicin, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Amrubicin is TOP2A. Amrubicin reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%amrubicin%" OR LOWER(tradeNames_string) LIKE "%amrubicin%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_3383', 'drugName': 'Amrubicin Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TOP2A (ENSG00000131747)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_3978', 'drugName': 'Amrubicin', 'drugMolec... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.113 | Q59 | What is the genetic target of the small molecule drug Terazosin Hydrochloride, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Terazosin Hydrochloride: ADRA1A, ADRA1D, and ADRA1B. Terazosin Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%terazosin hydrochloride%" OR LOWER(tradeNames_string) LIKE "%terazos... | [{'UUID': 'DrugGeneTargets_v2_1256', 'drugName': 'Terazosin Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRA1A (ENSG00000120907), ADRA1D (ENSG00000171873), ADRA1B (ENSG00000170214)', 'yearOfFirstApproval': 1987, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.43 | Q59 | What is the genetic target of the small molecule drug Alosetron, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Alosetron is HTR3A. Alosetron reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%alosetron%" OR LOWER(tradeNames_string) LIKE "%alosetron%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_4889', 'drugName': 'Alosetron', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR3A (ENSG00000166736)', 'yearOfFirstApproval': 2000, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_5986', 'drugName': 'Alosetron Hydrochloride', 'drugMol... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.128 | Q59 | What is the genetic target of the small molecule drug Selexipag, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Selexipag is PTGIR. Selexipag reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%selexipag%" OR LOWER(tradeNames_string) LIKE "%selexipag%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_5447', 'drugName': 'Selexipag', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGIR (ENSG00000160013)', 'yearOfFirstApproval': 2015, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.207 | Q59 | What is the genetic target of the small molecule drug Nortriptyline, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Nortriptyline: SLC6A4 and SLC6A2. Nortriptyline reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%nortriptyline%" OR LOWER(tradeNames_string) LIKE "%nortriptyline%" O... | [{'UUID': 'DrugGeneTargets_v2_598', 'drugName': 'Nortriptyline', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A4 (ENSG00000108576), SLC6A2 (ENSG00000103546)', 'yearOfFirstApproval': 1964, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_597', 'drugName': 'Nortr... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.53 | Q59 | What is the genetic target of the protein drug Insulin Susp Isophane Purified Pork, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Insulin Susp Isophane Purified Pork is INSR. Insulin Susp Isophane Purified Pork reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%insulin susp isophane purified pork%" OR LOWER(tradeNames_string) LI... | [{'UUID': 'DrugGeneTargets_v2_3326', 'drugName': 'Insulin Susp Isophane Purified Pork', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'INSR (ENSG00000171105)', 'yearOfFirstApproval': 1979, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.551 | Q59 | What is the genetic target of the small molecule drug Carphenazine, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Carphenazine: HTR2A, HTR2C, and DRD2. Carphenazine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%carphenazine%" OR LOWER(tradeNames_string) LIKE "%carphenazine%" OR ... | [{'UUID': 'DrugGeneTargets_v2_4893', 'drugName': 'Carphenazine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR2A (ENSG00000102468), HTR2C (ENSG00000147246), DRD2 (ENSG00000149295)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_31... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.71 | Q59 | What is the genetic target of the small molecule drug Nicardipine, and what is its status in clinical trials and FDA approval? | There are 4 genetic targets of the small molecule drug Nicardipine: CACNA1C, CACNA1S, CACNA1D, and CACNA1F. Nicardipine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%nicardipine%" OR LOWER(tradeNames_string) LIKE "%nicardipine%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_217', 'drugName': 'Nicardipine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CACNA1C (ENSG00000151067), CACNA1S (ENSG00000081248), CACNA1D (ENSG00000157388), CACNA1F (ENSG00000102001)', 'yearOfFirstApproval': 1988, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True},... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1816 | Q59 | What is the genetic target of the small molecule drug Phenelzine, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Phenelzine: MAOA and MAOB. Phenelzine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%phenelzine%" OR LOWER(tradeNames_string) LIKE "%phenelzine%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_351', 'drugName': 'Phenelzine Sulfate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'MAOA (ENSG00000189221), MAOB (ENSG00000069535)', 'yearOfFirstApproval': 1961, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4387', 'drugName': 'Phe... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1745 | Q59 | What is the genetic target of the small molecule drug Doxercalciferol, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Doxercalciferol is VDR. Doxercalciferol reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%doxercalciferol%" OR LOWER(tradeNames_string) LIKE "%doxercalciferol... | [{'UUID': 'DrugGeneTargets_v2_4241', 'drugName': 'Doxercalciferol', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'VDR (ENSG00000111424)', 'yearOfFirstApproval': 1999, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.186 | Q59 | What is the genetic target of the small molecule drug Levamlodipine Maleate, and what is its status in clinical trials and FDA approval? | There are 4 genetic targets of the small molecule drug Levamlodipine Maleate: CACNA1C, CACNA1S, CACNA1D, and CACNA1F. Levamlodipine Maleate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%levamlodipine maleate%" OR LOWER(tradeNames_string) LIKE "%levamlodi... | [{'UUID': 'DrugGeneTargets_v2_6132', 'drugName': 'Levamlodipine Maleate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CACNA1C (ENSG00000151067), CACNA1S (ENSG00000081248), CACNA1D (ENSG00000157388), CACNA1F (ENSG00000102001)', 'yearOfFirstApproval': 2019, 'maxClinicalTrialPhase': 4, 'drugIsApprov... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.140 | Q59 | What is the genetic target of the protein drug Frakefamide, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Frakefamide is OPRM1. Frakefamide reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%frakefamide%" OR LOWER(tradeNames_string) LIKE "%frakefamide%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_1644', 'drugName': 'Frakefamide', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'OPRM1 (ENSG00000112038)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.907 | Q59 | What is the genetic target of the gene drug Brexucabtagene Autoleucel, and what is its status in clinical trials and FDA approval? | The genetic target of the gene drug Brexucabtagene Autoleucel is CD19. Brexucabtagene Autoleucel reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%brexucabtagene autoleucel%" OR LOWER(tradeNames_string) LIKE "%brexu... | [{'UUID': 'DrugGeneTargets_v2_5372', 'drugName': 'Brexucabtagene Autoleucel', 'drugMolecularType': 'Gene', 'newLinkedTargets_string': 'CD19 (ENSG00000177455)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.803 | Q59 | What is the genetic target of the small molecule drug Haloperidol, and what is its status in clinical trials and FDA approval? | There are 4 genetic targets of the small molecule drug Haloperidol: DRD2, DRD3, DRD4, and HTR2A. Haloperidol reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%haloperidol%" OR LOWER(tradeNames_string) LIKE "%haloperidol%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_461', 'drugName': 'Haloperidol Decanoate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DRD2 (ENSG00000149295), DRD3 (ENSG00000151577), DRD4 (ENSG00000069696), HTR2A (ENSG00000102468)', 'yearOfFirstApproval': 1986, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, ... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.135 | Q59 | What is the genetic target of the small molecule drug Cabozantinib, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Cabozantinib: MET and KDR. Cabozantinib reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%cabozantinib%" OR LOWER(tradeNames_string) LIKE "%cabozantinib%" OR ... | [{'UUID': 'DrugGeneTargets_v2_3580', 'drugName': 'Cabozantinib S-Malate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'MET (ENSG00000105976), KDR (ENSG00000128052)', 'yearOfFirstApproval': 2012, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3579', 'drugName': 'C... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.83 | Q59 | What is the genetic target of the protein drug Ecallantide, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Ecallantide is KLKB1. Ecallantide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ecallantide%" OR LOWER(tradeNames_string) LIKE "%ecallantide%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_2279', 'drugName': 'Ecallantide', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'KLKB1 (ENSG00000164344)', 'yearOfFirstApproval': 2009, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1541 | Q59 | What is the genetic target of the small molecule drug Methixene, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Methixene: CHRM1 and HTR2C. Methixene reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%methixene%" OR LOWER(tradeNames_string) LIKE "%methixene%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_1167', 'drugName': 'Methixene', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRM1 (ENSG00000168539), HTR2C (ENSG00000147246)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1166', 'drugName': 'Methixene... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.547 | Q59 | What is the genetic target of the small molecule drug Entacapone, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Entacapone is COMT. Entacapone reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%entacapone%" OR LOWER(tradeNames_string) LIKE "%entacapone%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_3321', 'drugName': 'Entacapone', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'COMT (ENSG00000093010)', 'yearOfFirstApproval': 1999, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1596 | Q59 | What is the genetic target of the small molecule drug Asenapine, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Asenapine: HTR2A and DRD2. Asenapine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%asenapine%" OR LOWER(tradeNames_string) LIKE "%asenapine%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_4104', 'drugName': 'Asenapine Maleate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR2A (ENSG00000102468), DRD2 (ENSG00000149295)', 'yearOfFirstApproval': 2009, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4103', 'drugName': 'As... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.992 | Q59 | What is the genetic target of the small molecule drug Anatibant, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Anatibant is BDKRB2. Anatibant reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%anatibant%" OR LOWER(tradeNames_string) LIKE "%anatibant%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_297', 'drugName': 'Anatibant', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'BDKRB2 (ENSG00000168398)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.168 | Q59 | What is the genetic target of the small molecule drug Protriptyline, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Protriptyline: SLC6A2 and SLC6A4. Protriptyline reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%protriptyline%" OR LOWER(tradeNames_string) LIKE "%protriptyline%" O... | [{'UUID': 'DrugGeneTargets_v2_6366', 'drugName': 'Protriptyline', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A2 (ENSG00000103546), SLC6A4 (ENSG00000108576)', 'yearOfFirstApproval': 1967, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_6365', 'drugName': 'Pro... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.251 | Q59 | What is the genetic target of the small molecule drug Phenprocoumon, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Phenprocoumon is VKORC1. Phenprocoumon reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%phenprocoumon%" OR LOWER(tradeNames_string) LIKE "%phenprocoumon%" O... | [{'UUID': 'DrugGeneTargets_v2_1395', 'drugName': 'Phenprocoumon', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'VKORC1 (ENSG00000167397)', 'yearOfFirstApproval': 1957, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.452 | Q59 | What is the genetic target of the small molecule drug Estrogens, Conjugated, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Estrogens, Conjugated: ESR2 and ESR1. Estrogens, Conjugated reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%estrogens, conjugated%" OR LOWER(tradeNames_string) LIKE "%estrogens... | [{'UUID': 'DrugGeneTargets_v2_5682', 'drugName': 'Estrogens, Conjugated', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ESR2 (ENSG00000140009), ESR1 (ENSG00000091831)', 'yearOfFirstApproval': 1942, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_5680', 'drugName': ... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1148 | Q59 | What is the genetic target of the small molecule drug Mestranol, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Mestranol is ESR1. Mestranol reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%mestranol%" OR LOWER(tradeNames_string) LIKE "%mestranol%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_1659', 'drugName': 'Mestranol', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ESR1 (ENSG00000091831)', 'yearOfFirstApproval': 1961, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.865 | Q59 | What is the genetic target of the small molecule drug Prx-08066, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Prx-08066 is HTR2B. Prx-08066 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%prx-08066%" OR LOWER(tradeNames_string) LIKE "%prx-08066%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_3082', 'drugName': 'Prx-08066', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR2B (ENSG00000135914)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_4292', 'drugName': 'Prx-08066', 'drugMolecularType': 'Sm... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1233 | Q59 | What is the genetic target of the small molecule drug Rolapitant, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Rolapitant is TACR1. Rolapitant reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%rolapitant%" OR LOWER(tradeNames_string) LIKE "%rolapitant%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_3346', 'drugName': 'Rolapitant Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TACR1 (ENSG00000115353)', 'yearOfFirstApproval': 2015, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_5768', 'drugName': 'Rolapitant', 'drugM... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.100 | Q59 | What is the genetic target of the small molecule drug Tc-6987, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Tc-6987 is CHRNA7. Tc-6987 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tc-6987%" OR LOWER(tradeNames_string) LIKE "%tc-6987%" OR LOWER(drug... | [{'UUID': 'DrugGeneTargets_v2_5543', 'drugName': 'Tc-6987', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRNA7 (ENSG00000175344)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1974 | Q59 | What is the genetic target of the small molecule drug Thioridazine, and what is its status in clinical trials and FDA approval? | There are 5 genetic targets of the small molecule drug Thioridazine: DRD2, DRD3, DRD4, HTR2A, and HTR2C. Thioridazine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%thioridazine%" OR LOWER(tradeNames_string) LIKE "%thioridazine%" OR ... | [{'UUID': 'DrugGeneTargets_v2_6304', 'drugName': 'Thioridazine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR2C (ENSG00000147246), HTR2A (ENSG00000102468), DRD2 (ENSG00000149295), DRD3 (ENSG00000151577), DRD4 (ENSG00000069696)', 'yearOfFirstApproval': 1962, 'maxClinicalTrialPhase... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.744 | Q59 | What is the genetic target of the small molecule drug Upadacitinib, and what is its status in clinical trials and FDA approval? | There are 4 genetic targets of the small molecule drug Upadacitinib: JAK3, JAK1, JAK2, and TYK2. Upadacitinib reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%upadacitinib%" OR LOWER(tradeNames_string) LIKE "%upadacitinib%" OR ... | [{'UUID': 'DrugGeneTargets_v2_4653', 'drugName': 'Upadacitinib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'JAK3 (ENSG00000105639), JAK1 (ENSG00000162434), JAK2 (ENSG00000096968), TYK2 (ENSG00000105397)', 'yearOfFirstApproval': 2019, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1252 | Q59 | What is the genetic target of the small molecule drug Selgantolimod, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Selgantolimod is TLR8. Selgantolimod reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%selgantolimod%" OR LOWER(tradeNames_string) LIKE "%selgantolimod%" O... | [{'UUID': 'DrugGeneTargets_v2_3591', 'drugName': 'Selgantolimod', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TLR8 (ENSG00000101916)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.105 | Q59 | What is the genetic target of the small molecule drug Metocurine, and what is its status in clinical trials and FDA approval? | There are 5 genetic targets of the small molecule drug Metocurine: CHRNA1, CHRNG, CHRNB1, CHRND, and CHRNE. Metocurine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%metocurine%" OR LOWER(tradeNames_string) LIKE "%metocurine%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_2699', 'drugName': 'Metocurine Iodide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRNA1 (ENSG00000138435), CHRNG (ENSG00000196811), CHRNB1 (ENSG00000170175), CHRND (ENSG00000135902), CHRNE (ENSG00000108556)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.440 | Q59 | What is the genetic target of the small molecule drug Ibipinabant, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Ibipinabant is CNR1. Ibipinabant reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ibipinabant%" OR LOWER(tradeNames_string) LIKE "%ibipinabant%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_198', 'drugName': 'Ibipinabant', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CNR1 (ENSG00000118432)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.77 | Q59 | What is the genetic target of the oligosaccharide drug Idrabiotaparinux Sodium, and what is its status in clinical trials and FDA approval? | The genetic target of the oligosaccharide drug Idrabiotaparinux Sodium is F10. Idrabiotaparinux Sodium reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%idrabiotaparinux sodium%" OR LOWER(tradeNames_string) LIKE "%idrabio... | [{'UUID': 'DrugGeneTargets_v2_657', 'drugName': 'Idrabiotaparinux Sodium', 'drugMolecularType': 'Oligosaccharide', 'newLinkedTargets_string': 'F10 (ENSG00000126218)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1793 | Q59 | What is the genetic target of the small molecule drug Buclizine, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Buclizine is HRH1. Buclizine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%buclizine%" OR LOWER(tradeNames_string) LIKE "%buclizine%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_5050', 'drugName': 'Buclizine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH1 (ENSG00000196639)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2564', 'drugName': 'Buclizine Hydrochloride', 'drugMole... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1462 | Q59 | What is the genetic target of the small molecule drug Pl-225B, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Pl-225B is IGF1R. Pl-225B reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%pl-225b%" OR LOWER(tradeNames_string) LIKE "%pl-225b%" OR LOWER(drug... | [{'UUID': 'DrugGeneTargets_v2_4105', 'drugName': 'Pl-225B', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'IGF1R (ENSG00000140443)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.926 | Q59 | What is the genetic target of the oligonucleotide drug Olezarsen, and what is its status in clinical trials and FDA approval? | The genetic target of the oligonucleotide drug Olezarsen is APOC3. Olezarsen reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%olezarsen%" OR LOWER(tradeNames_string) LIKE "%olezarsen%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_2017', 'drugName': 'Olezarsen', 'drugMolecularType': 'Oligonucleotide', 'newLinkedTargets_string': 'APOC3 (ENSG00000110245)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1712 | Q59 | What is the genetic target of the oligosaccharide drug Heparin, and what is its status in clinical trials and FDA approval? | The genetic target of the oligosaccharide drug Heparin is SERPINC1. Heparin reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%heparin%" OR LOWER(tradeNames_string) LIKE "%heparin%" OR LOWER(drug... | [{'UUID': 'DrugGeneTargets_v2_4090', 'drugName': 'Heparin Sodium', 'drugMolecularType': 'Oligosaccharide', 'newLinkedTargets_string': 'SERPINC1 (ENSG00000117601)', 'yearOfFirstApproval': 1939, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_204', 'drugName': 'Dalteparin Sodium', 'drugM... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1671 | Q59 | What is the genetic target of the small molecule drug Testosterone Undecanoate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Testosterone Undecanoate is AR. Testosterone Undecanoate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%testosterone undecanoate%" OR LOWER(tradeNames_string) LIKE "%testos... | [{'UUID': 'DrugGeneTargets_v2_939', 'drugName': 'Testosterone Undecanoate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'AR (ENSG00000169083)', 'yearOfFirstApproval': 2014, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1621 | Q59 | What is the genetic target of the antibody drug Indatuximab Ravtansine, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Indatuximab Ravtansine is SDC1. Indatuximab Ravtansine reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%indatuximab ravtansine%" OR LOWER(tradeNames_string) LIKE "%indatuxi... | [{'UUID': 'DrugGeneTargets_v2_294', 'drugName': 'Indatuximab Ravtansine', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'SDC1 (ENSG00000115884)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.769 | Q59 | What is the genetic target of the small molecule drug Osimertinib Mesylate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Osimertinib Mesylate is EGFR. Osimertinib Mesylate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%osimertinib mesylate%" OR LOWER(tradeNames_string) LIKE "%osimertini... | [{'UUID': 'DrugGeneTargets_v2_649', 'drugName': 'Osimertinib Mesylate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'EGFR (ENSG00000146648)', 'yearOfFirstApproval': 2015, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.998 | Q59 | What is the genetic target of the small molecule drug Bepotastine, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Bepotastine is HRH1. Bepotastine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%bepotastine%" OR LOWER(tradeNames_string) LIKE "%bepotastine%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_3215', 'drugName': 'Bepotastine Besylate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH1 (ENSG00000196639)', 'yearOfFirstApproval': 2009, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_6339', 'drugName': 'Bepotastine', 'drugMolec... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.394 | Q59 | What is the genetic target of the small molecule drug Quinidine, and what is its status in clinical trials and FDA approval? | There are 10 genetic targets of the small molecule drug Quinidine: SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. Quinidine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%quinidine%" OR LOWER(tradeNames_string) LIKE "%quinidine%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_2256', 'drugName': 'Quinidine Gluconate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SCN1A (ENSG00000144285), SCN5A (ENSG00000183873), SCN4A (ENSG00000007314), SCN7A (ENSG00000136546), SCN2A (ENSG00000136531), SCN9A (ENSG00000169432), SCN3A (ENSG00000153253), SCN11A... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.238 | Q59 | What is the genetic target of the small molecule drug Rimiterol, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Rimiterol is ADRB2. Rimiterol reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%rimiterol%" OR LOWER(tradeNames_string) LIKE "%rimiterol%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_457', 'drugName': 'Rimiterol', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRB2 (ENSG00000169252)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1508 | Q59 | What is the genetic target of the small molecule drug Brompheniramine, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Brompheniramine is HRH1. Brompheniramine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%brompheniramine%" OR LOWER(tradeNames_string) LIKE "%brompheniramine... | [{'UUID': 'DrugGeneTargets_v2_6367', 'drugName': 'Brompheniramine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH1 (ENSG00000196639)', 'yearOfFirstApproval': 1957, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1014', 'drugName': 'Brompheniramine Maleate', 'dr... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.270 | Q59 | What is the genetic target of the small molecule drug Duloxetine Hydrochloride, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Duloxetine Hydrochloride: SLC6A4 and SLC6A2. Duloxetine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%duloxetine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%duloxe... | [{'UUID': 'DrugGeneTargets_v2_5702', 'drugName': 'Duloxetine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A4 (ENSG00000108576), SLC6A2 (ENSG00000103546)', 'yearOfFirstApproval': 2004, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_5703', 'drug... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1187 | Q59 | What is the genetic target of the small molecule drug Bethanidine Sulfate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Bethanidine Sulfate is SLC6A2. Bethanidine Sulfate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%bethanidine sulfate%" OR LOWER(tradeNames_string) LIKE "%bethanidine... | [{'UUID': 'DrugGeneTargets_v2_4786', 'drugName': 'Bethanidine Sulfate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A2 (ENSG00000103546)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.120 | Q59 | What is the genetic target of the antibody drug Batoclimab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Batoclimab is FCGRT. Batoclimab reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%batoclimab%" OR LOWER(tradeNames_string) LIKE "%batoclimab%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_4696', 'drugName': 'Batoclimab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'FCGRT (ENSG00000104870)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1607 | Q59 | What is the genetic target of the small molecule drug Dabigatran Etexilate Mesylate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Dabigatran Etexilate Mesylate is F2. Dabigatran Etexilate Mesylate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%dabigatran etexilate mesylate%" OR LOWER(tradeNames_string) LIKE "%d... | [{'UUID': 'DrugGeneTargets_v2_5711', 'drugName': 'Dabigatran Etexilate Mesylate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'F2 (ENSG00000180210)', 'yearOfFirstApproval': 2010, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.680 | Q59 | What is the genetic target of the antibody drug Denintuzumab Mafodotin, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Denintuzumab Mafodotin is CD19. Denintuzumab Mafodotin reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%denintuzumab mafodotin%" OR LOWER(tradeNames_string) LIKE "%denintuz... | [{'UUID': 'DrugGeneTargets_v2_4181', 'drugName': 'Denintuzumab Mafodotin', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'CD19 (ENSG00000177455)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.252 | Q59 | What is the genetic target of the protein drug Teriparatide, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Teriparatide is PTH1R. Teriparatide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%teriparatide%" OR LOWER(tradeNames_string) LIKE "%teriparatide%" OR ... | [{'UUID': 'DrugGeneTargets_v2_3571', 'drugName': 'Teriparatide Acetate', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'PTH1R (ENSG00000160801)', 'yearOfFirstApproval': 1987, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2407', 'drugName': 'Teriparatide', 'drugMolecularT... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1958 | Q59 | What is the genetic target of the small molecule drug Linerixibat, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Linerixibat is SLC10A2. Linerixibat reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%linerixibat%" OR LOWER(tradeNames_string) LIKE "%linerixibat%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_1185', 'drugName': 'Linerixibat', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC10A2 (ENSG00000125255)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1995 | Q59 | What is the genetic target of the small molecule drug Apomorphine Hydrochloride, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Apomorphine Hydrochloride: DRD2, DRD3, and DRD4. Apomorphine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%apomorphine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%apomo... | [{'UUID': 'DrugGeneTargets_v2_3300', 'drugName': 'Apomorphine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DRD2 (ENSG00000149295), DRD3 (ENSG00000151577), DRD4 (ENSG00000069696)', 'yearOfFirstApproval': 2004, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.97 | Q59 | What is the genetic target of the small molecule drug Lithium Citrate, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Lithium Citrate: IMPA1, GSK3A, and GSK3B. Lithium Citrate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%lithium citrate%" OR LOWER(tradeNames_string) LIKE "%lithium citrate... | [{'UUID': 'DrugGeneTargets_v2_2749', 'drugName': 'Lithium Citrate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'IMPA1 (ENSG00000133731), GSK3A (ENSG00000105723), GSK3B (ENSG00000082701)', 'yearOfFirstApproval': 1980, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.34 | Q59 | What is the genetic target of the small molecule drug Isoxsuprine, and what is its status in clinical trials and FDA approval? | There are 4 genetic targets of the small molecule drug Isoxsuprine: ADRB2, ADRA1A, ADRA1D, and ADRA1B. Isoxsuprine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%isoxsuprine%" OR LOWER(tradeNames_string) LIKE "%isoxsuprine%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_5346', 'drugName': 'Isoxsuprine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRB2 (ENSG00000169252), ADRA1A (ENSG00000120907), ADRA1D (ENSG00000171873), ADRA1B (ENSG00000170214)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1465 | Q59 | What is the genetic target of the small molecule drug Lasofoxifene, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Lasofoxifene: ESR2 and ESR1. Lasofoxifene reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%lasofoxifene%" OR LOWER(tradeNames_string) LIKE "%lasofoxifene%" OR ... | [{'UUID': 'DrugGeneTargets_v2_5303', 'drugName': 'Lasofoxifene', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ESR2 (ENSG00000140009), ESR1 (ENSG00000091831)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1668 | Q59 | What is the genetic target of the small molecule drug Pirbuterol, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Pirbuterol is ADRB2. Pirbuterol reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%pirbuterol%" OR LOWER(tradeNames_string) LIKE "%pirbuterol%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_6175', 'drugName': 'Pirbuterol', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRB2 (ENSG00000169252)', 'yearOfFirstApproval': 1986, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3043', 'drugName': 'Pirbuterol Acetate', 'drugMolecul... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.454 | Q59 | What is the genetic target of the small molecule drug Remifentanil Hydrochloride, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Remifentanil Hydrochloride is OPRM1. Remifentanil Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%remifentanil hydrochloride%" OR LOWER(tradeNames_string) LIKE "%remi... | [{'UUID': 'DrugGeneTargets_v2_577', 'drugName': 'Remifentanil Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'OPRM1 (ENSG00000112038)', 'yearOfFirstApproval': 1996, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.723 | Q59 | What is the genetic target of the small molecule drug Mivacurium Chloride, and what is its status in clinical trials and FDA approval? | There are 5 genetic targets of the small molecule drug Mivacurium Chloride: CHRNA1, CHRNG, CHRNB1, CHRND, and CHRNE. Mivacurium Chloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%mivacurium chloride%" OR LOWER(tradeNames_string) LIKE "%mivacurium ... | [{'UUID': 'DrugGeneTargets_v2_3976', 'drugName': 'Mivacurium Chloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRNA1 (ENSG00000138435), CHRNG (ENSG00000196811), CHRNB1 (ENSG00000170175), CHRND (ENSG00000135902), CHRNE (ENSG00000108556)', 'yearOfFirstApproval': 1992, 'maxClinicalTrialPhase':... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1261 | Q59 | What is the genetic target of the small molecule drug Fluphenazine Hydrochloride, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Fluphenazine Hydrochloride is DRD2. Fluphenazine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%fluphenazine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%flup... | [{'UUID': 'DrugGeneTargets_v2_5319', 'drugName': 'Fluphenazine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DRD2 (ENSG00000149295)', 'yearOfFirstApproval': 1959, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1598 | Q59 | What is the genetic target of the small molecule drug Siremadlin, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Siremadlin: TP53 and MDM2. Siremadlin reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%siremadlin%" OR LOWER(tradeNames_string) LIKE "%siremadlin%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_3936', 'drugName': 'Siremadlin', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TP53 (ENSG00000141510), MDM2 (ENSG00000135679)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1 | Q59 | What is the genetic target of the small molecule drug Masupirdine, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Masupirdine is HTR6. Masupirdine reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%masupirdine%" OR LOWER(tradeNames_string) LIKE "%masupirdine%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_4255', 'drugName': 'Masupirdine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR6 (ENSG00000158748)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1377 | Q59 | What is the genetic target of the small molecule drug Omeprazole, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Omeprazole: ATP4A and ATP4B. Omeprazole reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%omeprazole%" OR LOWER(tradeNames_string) LIKE "%omeprazole%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_3369', 'drugName': 'Omeprazole Magnesium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ATP4A (ENSG00000105675), ATP4B (ENSG00000186009)', 'yearOfFirstApproval': 2003, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2162', 'drugName':... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1110 | Q59 | What is the genetic target of the small molecule drug Fosphenytoin, and what is its status in clinical trials and FDA approval? | There are 10 genetic targets of the small molecule drug Fosphenytoin: SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. Fosphenytoin reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%fosphenytoin%" OR LOWER(tradeNames_string) LIKE "%fosphenytoin%" OR ... | [{'UUID': 'DrugGeneTargets_v2_993', 'drugName': 'Fosphenytoin', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SCN1A (ENSG00000144285), SCN5A (ENSG00000183873), SCN4A (ENSG00000007314), SCN7A (ENSG00000136546), SCN2A (ENSG00000136531), SCN9A (ENSG00000169432), SCN3A (ENSG00000153253), SCN11A (ENSG00... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1117 | Q59 | What is the genetic target of the antibody drug Demcizumab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Demcizumab is DLL4. Demcizumab reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%demcizumab%" OR LOWER(tradeNames_string) LIKE "%demcizumab%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_3542', 'drugName': 'Demcizumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'DLL4 (ENSG00000128917)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1591 | Q59 | What is the genetic target of the small molecule drug Amrubicin Hydrochloride, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Amrubicin Hydrochloride is TOP2A. Amrubicin Hydrochloride reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%amrubicin hydrochloride%" OR LOWER(tradeNames_string) LIKE "%amrubic... | [{'UUID': 'DrugGeneTargets_v2_3383', 'drugName': 'Amrubicin Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TOP2A (ENSG00000131747)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.85 | Q59 | What is the genetic target of the small molecule drug Azd-4547, and what is its status in clinical trials and FDA approval? | There are 4 genetic targets of the small molecule drug Azd-4547: FGFR3, FGFR1, FGFR4, and FGFR2. Azd-4547 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%azd-4547%" OR LOWER(tradeNames_string) LIKE "%azd-4547%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_3850', 'drugName': 'Azd-4547', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'FGFR3 (ENSG00000068078), FGFR1 (ENSG00000077782), FGFR4 (ENSG00000160867), FGFR2 (ENSG00000066468)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
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