uuid stringlengths 4 8 | template_uuid stringclasses 40
values | question stringlengths 13 193 | answer stringlengths 29 2.2k | benchmark_query stringlengths 133 622 | execution_results stringlengths 2 1.14M | query_type stringclasses 2
values | sql_category stringclasses 26
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Q59.1294 | Q59 | What is the genetic target of the small molecule drug Mecamylamine Hydrochloride, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Mecamylamine Hydrochloride: CHRNB4 and CHRNA3. Mecamylamine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%mecamylamine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%meca... | [{'UUID': 'DrugGeneTargets_v2_1272', 'drugName': 'Mecamylamine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRNB4 (ENSG00000117971), CHRNA3 (ENSG00000080644)', 'yearOfFirstApproval': 1956, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.683 | Q59 | What is the genetic target of the small molecule drug Tapinarof, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Tapinarof is AHR. Tapinarof reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tapinarof%" OR LOWER(tradeNames_string) LIKE "%tapinarof%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_192', 'drugName': 'Tapinarof', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'AHR (ENSG00000106546)', 'yearOfFirstApproval': 2022, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1677 | Q59 | What is the genetic target of the small molecule drug Erlotinib, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Erlotinib is EGFR. Erlotinib reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%erlotinib%" OR LOWER(tradeNames_string) LIKE "%erlotinib%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_137', 'drugName': 'Erlotinib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'EGFR (ENSG00000146648)', 'yearOfFirstApproval': 2004, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3145', 'drugName': 'Erlotinib Hydrochloride', 'drugMolec... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1055 | Q59 | What is the genetic target of the antibody drug Ruplizumab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Ruplizumab is CD40LG. Ruplizumab reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ruplizumab%" OR LOWER(tradeNames_string) LIKE "%ruplizumab%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_230', 'drugName': 'Ruplizumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'CD40LG (ENSG00000102245)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.777 | Q59 | What is the genetic target of the small molecule drug Gs-9667, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Gs-9667 is ADORA1. Gs-9667 reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%gs-9667%" OR LOWER(tradeNames_string) LIKE "%gs-9667%" OR LOWER(drug... | [{'UUID': 'DrugGeneTargets_v2_4180', 'drugName': 'Gs-9667', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADORA1 (ENSG00000163485)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1289 | Q59 | What is the genetic target of the protein drug Ceruletide, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Ceruletide is CCKAR. Ceruletide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ceruletide%" OR LOWER(tradeNames_string) LIKE "%ceruletide%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_3461', 'drugName': 'Ceruletide Diethylamine', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'CCKAR (ENSG00000163394)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3801', 'drugName': 'Ceruletide', 'drugMolecular... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1946 | Q59 | What is the genetic target of the small molecule drug Epinephrine, and what is its status in clinical trials and FDA approval? | There are 9 genetic targets of the small molecule drug Epinephrine: ADRA1A, ADRA2A, ADRB1, ADRB2, ADRA2C, ADRA1D, ADRA1B, ADRA2B, and ADRB3. Epinephrine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%epinephrine%" OR LOWER(tradeNames_string) LIKE "%epinephrine%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_1884', 'drugName': 'Epinephrine Bitartrate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRA1A (ENSG00000120907), ADRA2A (ENSG00000150594), ADRB1 (ENSG00000043591), ADRB2 (ENSG00000169252), ADRA2C (ENSG00000184160), ADRA1D (ENSG00000171873), ADRA1B (ENSG00000170214)... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1581 | Q59 | What is the genetic target of the small molecule drug Fluvoxamine Maleate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Fluvoxamine Maleate is SLC6A4. Fluvoxamine Maleate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%fluvoxamine maleate%" OR LOWER(tradeNames_string) LIKE "%fluvoxamine... | [{'UUID': 'DrugGeneTargets_v2_1759', 'drugName': 'Fluvoxamine Maleate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A4 (ENSG00000108576)', 'yearOfFirstApproval': 1994, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1490 | Q59 | What is the genetic target of the antibody drug Brolucizumab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Brolucizumab is VEGFA. Brolucizumab reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%brolucizumab%" OR LOWER(tradeNames_string) LIKE "%brolucizumab%" OR ... | [{'UUID': 'DrugGeneTargets_v2_2206', 'drugName': 'Brolucizumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'VEGFA (ENSG00000112715)', 'yearOfFirstApproval': 2019, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.410 | Q59 | What is the genetic target of the protein drug Peginesatide Acetate, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Peginesatide Acetate is EPOR. Peginesatide Acetate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%peginesatide acetate%" OR LOWER(tradeNames_string) LIKE "%peginesati... | [{'UUID': 'DrugGeneTargets_v2_5606', 'drugName': 'Peginesatide Acetate', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'EPOR (ENSG00000187266)', 'yearOfFirstApproval': 2012, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1728 | Q59 | What is the genetic target of the small molecule drug Indacaterol Maleate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Indacaterol Maleate is ADRB2. Indacaterol Maleate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%indacaterol maleate%" OR LOWER(tradeNames_string) LIKE "%indacaterol... | [{'UUID': 'DrugGeneTargets_v2_3427', 'drugName': 'Indacaterol Maleate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRB2 (ENSG00000169252)', 'yearOfFirstApproval': 2011, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1298 | Q59 | What is the genetic target of the small molecule drug Cal-263, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Cal-263: PIK3CD and PIK3CG. Cal-263 reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%cal-263%" OR LOWER(tradeNames_string) LIKE "%cal-263%" OR LOWER(drug... | [{'UUID': 'DrugGeneTargets_v2_4879', 'drugName': 'Cal-263', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PIK3CD (ENSG00000171608), PIK3CG (ENSG00000105851)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_4880', 'drugName': 'Cal-263', '... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1665 | Q59 | What is the genetic target of the small molecule drug Ambenonium, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Ambenonium is ACHE. Ambenonium reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ambenonium%" OR LOWER(tradeNames_string) LIKE "%ambenonium%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_150', 'drugName': 'Ambenonium Chloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ACHE (ENSG00000087085)', 'yearOfFirstApproval': 1956, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_253', 'drugName': 'Ambenonium', 'drugMolecular... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.107 | Q59 | What is the genetic target of the small molecule drug Rivaroxaban, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Rivaroxaban is F10. Rivaroxaban reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%rivaroxaban%" OR LOWER(tradeNames_string) LIKE "%rivaroxaban%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_816', 'drugName': 'Rivaroxaban', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'F10 (ENSG00000126218)', 'yearOfFirstApproval': 2011, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.695 | Q59 | What is the genetic target of the antibody drug Elotuzumab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Elotuzumab is SLAMF7. Elotuzumab reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%elotuzumab%" OR LOWER(tradeNames_string) LIKE "%elotuzumab%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_5815', 'drugName': 'Elotuzumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'SLAMF7 (ENSG00000026751)', 'yearOfFirstApproval': 2015, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1305 | Q59 | What is the genetic target of the small molecule drug Amphetamine Sulfate, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Amphetamine Sulfate: SLC6A3 and SLC6A2. Amphetamine Sulfate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%amphetamine sulfate%" OR LOWER(tradeNames_string) LIKE "%amphetamine... | [{'UUID': 'DrugGeneTargets_v2_1032', 'drugName': 'Dextroamphetamine Sulfate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A2 (ENSG00000103546), SLC6A3 (ENSG00000142319), SLC18A2 (ENSG00000165646)', 'yearOfFirstApproval': 1960, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'Dru... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.833 | Q59 | What is the genetic target of the small molecule drug Roflumilast, and what is its status in clinical trials and FDA approval? | There are 4 genetic targets of the small molecule drug Roflumilast: PDE4A, PDE4D, PDE4B, and PDE4C. Roflumilast reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%roflumilast%" OR LOWER(tradeNames_string) LIKE "%roflumilast%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_5055', 'drugName': 'Roflumilast', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PDE4A (ENSG00000065989), PDE4D (ENSG00000113448), PDE4B (ENSG00000184588), PDE4C (ENSG00000105650)', 'yearOfFirstApproval': 2011, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.64 | Q59 | What is the genetic target of the small molecule drug Acalabrutinib Maleate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Acalabrutinib Maleate is BTK. Acalabrutinib Maleate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%acalabrutinib maleate%" OR LOWER(tradeNames_string) LIKE "%acalabrut... | [{'UUID': 'DrugGeneTargets_v2_6297', 'drugName': 'Acalabrutinib Maleate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'BTK (ENSG00000010671)', 'yearOfFirstApproval': 2022, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.859 | Q59 | What is the genetic target of the small molecule drug Bazedoxifene Acetate, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Bazedoxifene Acetate: ESR2 and ESR1. Bazedoxifene Acetate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%bazedoxifene acetate%" OR LOWER(tradeNames_string) LIKE "%bazedoxife... | [{'UUID': 'DrugGeneTargets_v2_1341', 'drugName': 'Bazedoxifene Acetate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ESR2 (ENSG00000140009), ESR1 (ENSG00000091831)', 'yearOfFirstApproval': 2009, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1355 | Q59 | What is the genetic target of the small molecule drug Warfarin, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Warfarin is VKORC1. Warfarin reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%warfarin%" OR LOWER(tradeNames_string) LIKE "%warfarin%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_38', 'drugName': 'Warfarin Sodium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'VKORC1 (ENSG00000167397)', 'yearOfFirstApproval': 1954, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3808', 'drugName': 'Warfarin', 'drugMolecularType... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.226 | Q59 | What is the genetic target of the antibody drug Talacotuzumab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Talacotuzumab is IL3RA. Talacotuzumab reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%talacotuzumab%" OR LOWER(tradeNames_string) LIKE "%talacotuzumab%" O... | [{'UUID': 'DrugGeneTargets_v2_915', 'drugName': 'Talacotuzumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'IL3RA (ENSG00000185291)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.148 | Q59 | What is the genetic target of the small molecule drug Alvimopan, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Alvimopan is OPRM1. Alvimopan reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%alvimopan%" OR LOWER(tradeNames_string) LIKE "%alvimopan%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_4682', 'drugName': 'Alvimopan', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'OPRM1 (ENSG00000112038)', 'yearOfFirstApproval': 2008, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1097 | Q59 | What is the genetic target of the small molecule drug Moxonidine, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Moxonidine is NISCH. Moxonidine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%moxonidine%" OR LOWER(tradeNames_string) LIKE "%moxonidine%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_2347', 'drugName': 'Moxonidine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'NISCH (ENSG00000010322)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.379 | Q59 | What is the genetic target of the small molecule drug Gsk-610677, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Gsk-610677 is MAPK14. Gsk-610677 reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%gsk-610677%" OR LOWER(tradeNames_string) LIKE "%gsk-610677%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_4762', 'drugName': 'Gsk-610677', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'MAPK14 (ENSG00000112062)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1422 | Q59 | What is the genetic target of the protein drug Insulin Susp Isophane Semisynthetic Purified Human, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Insulin Susp Isophane Semisynthetic Purified Human is INSR. Insulin Susp Isophane Semisynthetic Purified Human reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%insulin susp isophane semisynthetic purified human%" OR LOWER(tradeN... | [{'UUID': 'DrugGeneTargets_v2_5849', 'drugName': 'Insulin Susp Isophane Semisynthetic Purified Human', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'INSR (ENSG00000171105)', 'yearOfFirstApproval': 1985, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1152 | Q59 | What is the genetic target of the small molecule drug Acetylcholine Chloride, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Acetylcholine Chloride is CHRM3. Acetylcholine Chloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%acetylcholine chloride%" OR LOWER(tradeNames_string) LIKE "%acetylch... | [{'UUID': 'DrugGeneTargets_v2_3911', 'drugName': 'Acetylcholine Chloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRM3 (ENSG00000133019)', 'yearOfFirstApproval': 1973, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1828 | Q59 | What is the genetic target of the small molecule drug Olorinab, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Olorinab is CNR2. Olorinab reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%olorinab%" OR LOWER(tradeNames_string) LIKE "%olorinab%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_2012', 'drugName': 'Olorinab', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CNR2 (ENSG00000188822)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1496 | Q59 | What is the genetic target of the protein drug Terlipressin, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the protein drug Terlipressin: AVPR1A, AVPR1B, and AVPR2. Terlipressin reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%terlipressin%" OR LOWER(tradeNames_string) LIKE "%terlipressin%" OR ... | [{'UUID': 'DrugGeneTargets_v2_5948', 'drugName': 'Terlipressin', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'AVPR1A (ENSG00000166148), AVPR1B (ENSG00000198049), AVPR2 (ENSG00000126895)', 'yearOfFirstApproval': 2022, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_5949',... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1602 | Q59 | What is the genetic target of the small molecule drug Fosnetupitant, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Fosnetupitant is TACR1. Fosnetupitant reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%fosnetupitant%" OR LOWER(tradeNames_string) LIKE "%fosnetupitant%" O... | [{'UUID': 'DrugGeneTargets_v2_1941', 'drugName': 'Fosnetupitant', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TACR1 (ENSG00000115353)', 'yearOfFirstApproval': 2018, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4376', 'drugName': 'Fosnetupitant Chloride Hydroch... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1759 | Q59 | What is the genetic target of the antibody drug Trc-093, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Trc-093 is COL4A4. Trc-093 reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%trc-093%" OR LOWER(tradeNames_string) LIKE "%trc-093%" OR LOWER(drug... | [{'UUID': 'DrugGeneTargets_v2_1022', 'drugName': 'Trc-093', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'COL4A4 (ENSG00000081052)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.10 | Q59 | What is the genetic target of the small molecule drug Argatroban, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Argatroban is F2. Argatroban reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%argatroban%" OR LOWER(tradeNames_string) LIKE "%argatroban%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_2622', 'drugName': 'Argatroban', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'F2 (ENSG00000180210)', 'yearOfFirstApproval': 2000, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.455 | Q59 | What is the genetic target of the small molecule drug Talnetant, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Talnetant is TACR3. Talnetant reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%talnetant%" OR LOWER(tradeNames_string) LIKE "%talnetant%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_317', 'drugName': 'Talnetant', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TACR3 (ENSG00000169836)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.715 | Q59 | What is the genetic target of the small molecule drug Polyestradiol Phosphate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Polyestradiol Phosphate is ESR1. Polyestradiol Phosphate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%polyestradiol phosphate%" OR LOWER(tradeNames_string) LIKE "%polyest... | [{'UUID': 'DrugGeneTargets_v2_5051', 'drugName': 'Polyestradiol Phosphate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ESR1 (ENSG00000091831)', 'yearOfFirstApproval': 1957, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.258 | Q59 | What is the genetic target of the small molecule drug Epoprostenol Sodium, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Epoprostenol Sodium is PTGIR. Epoprostenol Sodium reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%epoprostenol sodium%" OR LOWER(tradeNames_string) LIKE "%epoprosteno... | [{'UUID': 'DrugGeneTargets_v2_1500', 'drugName': 'Epoprostenol Sodium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGIR (ENSG00000160013)', 'yearOfFirstApproval': 1995, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.889 | Q59 | What is the genetic target of the small molecule drug Mitoxantrone Hydrochloride, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Mitoxantrone Hydrochloride is TOP2A. Mitoxantrone Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%mitoxantrone hydrochloride%" OR LOWER(tradeNames_string) LIKE "%mito... | [{'UUID': 'DrugGeneTargets_v2_4715', 'drugName': 'Mitoxantrone Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TOP2A (ENSG00000131747)', 'yearOfFirstApproval': 1987, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.395 | Q59 | What is the genetic target of the small molecule drug Paroxetine Hydrochloride, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Paroxetine Hydrochloride is SLC6A4. Paroxetine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%paroxetine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%paroxe... | [{'UUID': 'DrugGeneTargets_v2_4720', 'drugName': 'Paroxetine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A4 (ENSG00000108576)', 'yearOfFirstApproval': 1992, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3442', 'drugName': 'Paroxetine Hydroch... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.916 | Q59 | What is the genetic target of the small molecule drug Moexipril Hydrochloride, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Moexipril Hydrochloride is ACE. Moexipril Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%moexipril hydrochloride%" OR LOWER(tradeNames_string) LIKE "%moexipr... | [{'UUID': 'DrugGeneTargets_v2_517', 'drugName': 'Moexipril Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ACE (ENSG00000159640)', 'yearOfFirstApproval': 1995, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.932 | Q59 | What is the genetic target of the small molecule drug Sar-125844, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Sar-125844 is MET. Sar-125844 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%sar-125844%" OR LOWER(tradeNames_string) LIKE "%sar-125844%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_5030', 'drugName': 'Sar-125844', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'MET (ENSG00000105976)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1704 | Q59 | What is the genetic target of the protein drug Pramlintide, and what is its status in clinical trials and FDA approval? | There are 4 genetic targets of the protein drug Pramlintide: CALCR, RAMP1, RAMP2, and RAMP3. Pramlintide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%pramlintide%" OR LOWER(tradeNames_string) LIKE "%pramlintide%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_359', 'drugName': 'Pramlintide', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'CALCR (ENSG00000004948), RAMP1 (ENSG00000132329), RAMP2 (ENSG00000131477), RAMP3 (ENSG00000122679)', 'yearOfFirstApproval': 2005, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'Drug... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1231 | Q59 | What is the genetic target of the small molecule drug Mbx-2044, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Mbx-2044 is PPARG. Mbx-2044 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%mbx-2044%" OR LOWER(tradeNames_string) LIKE "%mbx-2044%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_5830', 'drugName': 'Mbx-2044', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PPARG (ENSG00000132170)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.466 | Q59 | What is the genetic target of the small molecule drug Bupropion Hydrobromide, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Bupropion Hydrobromide: SLC6A3 and SLC6A2. Bupropion Hydrobromide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%bupropion hydrobromide%" OR LOWER(tradeNames_string) LIKE "%bupropio... | [{'UUID': 'DrugGeneTargets_v2_1806', 'drugName': 'Bupropion Hydrobromide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A3 (ENSG00000142319), SLC6A2 (ENSG00000103546)', 'yearOfFirstApproval': 2008, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1807', 'drugNa... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1967 | Q59 | What is the genetic target of the small molecule drug Safinamide, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Safinamide is MAOB. Safinamide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%safinamide%" OR LOWER(tradeNames_string) LIKE "%safinamide%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_4183', 'drugName': 'Safinamide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'MAOB (ENSG00000069535)', 'yearOfFirstApproval': 2017, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1874', 'drugName': 'Safinamide Mesylate', 'drugMolecul... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1178 | Q59 | What is the genetic target of the small molecule drug Clocortolone Pivalate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Clocortolone Pivalate is NR3C1. Clocortolone Pivalate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%clocortolone pivalate%" OR LOWER(tradeNames_string) LIKE "%clocortol... | [{'UUID': 'DrugGeneTargets_v2_4803', 'drugName': 'Clocortolone Pivalate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'NR3C1 (ENSG00000113580)', 'yearOfFirstApproval': 1977, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.967 | Q59 | What is the genetic target of the small molecule drug Tirofiban Hydrochloride, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Tirofiban Hydrochloride: ITGB3 and ITGA2B. Tirofiban Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tirofiban hydrochloride%" OR LOWER(tradeNames_string) LIKE "%tirofib... | [{'UUID': 'DrugGeneTargets_v2_2897', 'drugName': 'Tirofiban Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ITGB3 (ENSG00000259207), ITGA2B (ENSG00000005961)', 'yearOfFirstApproval': 1998, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.507 | Q59 | What is the genetic target of the small molecule drug Fesoterodine, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Fesoterodine: CHRM3 and CHRM2. Fesoterodine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%fesoterodine%" OR LOWER(tradeNames_string) LIKE "%fesoterodine%" OR ... | [{'UUID': 'DrugGeneTargets_v2_1582', 'drugName': 'Fesoterodine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRM3 (ENSG00000133019), CHRM2 (ENSG00000181072)', 'yearOfFirstApproval': 2008, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1581', 'drugName': 'Fesote... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.746 | Q59 | What is the genetic target of the protein drug Insulin Glulisine, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Insulin Glulisine is INSR. Insulin Glulisine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%insulin glulisine%" OR LOWER(tradeNames_string) LIKE "%insulin gluli... | [{'UUID': 'DrugGeneTargets_v2_5441', 'drugName': 'Insulin Glulisine', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'INSR (ENSG00000171105)', 'yearOfFirstApproval': 2004, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1851 | Q59 | What is the genetic target of the protein drug Carbetocin, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Carbetocin is OXTR. Carbetocin reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%carbetocin%" OR LOWER(tradeNames_string) LIKE "%carbetocin%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_6062', 'drugName': 'Carbetocin', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'OXTR (ENSG00000180914)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.875 | Q59 | What is the genetic target of the small molecule drug Vipivotide Tetraxetan Lutetium, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Vipivotide Tetraxetan Lutetium is FOLH1. Vipivotide Tetraxetan Lutetium reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%vipivotide tetraxetan lutetium%" OR LOWER(tradeNames_string) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_5373', 'drugName': 'Vipivotide Tetraxetan Lutetium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'FOLH1 (ENSG00000086205)', 'yearOfFirstApproval': 2022, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_5876', 'drugName': 'Lutetium Lu 1... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.738 | Q59 | What is the genetic target of the small molecule drug Ephedrine Hydrochloride, and what is its status in clinical trials and FDA approval? | There are 9 genetic targets of the small molecule drug Ephedrine Hydrochloride: ADRA1A, ADRA2A, ADRB1, ADRB2, ADRA2C, ADRA1D, ADRA1B, ADRA2B, and ADRB3. Ephedrine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ephedrine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%ephedri... | [{'UUID': 'DrugGeneTargets_v2_5557', 'drugName': 'Methamphetamine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A4 (ENSG00000108576), SLC6A3 (ENSG00000142319), SLC6A2 (ENSG00000103546)', 'yearOfFirstApproval': 1943, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': '... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.545 | Q59 | What is the genetic target of the small molecule drug Rimexolone, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Rimexolone is NR3C1. Rimexolone reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%rimexolone%" OR LOWER(tradeNames_string) LIKE "%rimexolone%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_5317', 'drugName': 'Rimexolone', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'NR3C1 (ENSG00000113580)', 'yearOfFirstApproval': 1994, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1211 | Q59 | What is the genetic target of the small molecule drug Decamethonium, and what is its status in clinical trials and FDA approval? | There are 5 genetic targets of the small molecule drug Decamethonium: CHRNA1, CHRNG, CHRNB1, CHRND, and CHRNE. Decamethonium reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%decamethonium%" OR LOWER(tradeNames_string) LIKE "%decamethonium%" O... | [{'UUID': 'DrugGeneTargets_v2_922', 'drugName': 'Decamethonium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRNA1 (ENSG00000138435), CHRNG (ENSG00000196811), CHRNB1 (ENSG00000170175), CHRND (ENSG00000135902), CHRNE (ENSG00000108556)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'dr... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.704 | Q59 | What is the genetic target of the small molecule drug Ralimetinib, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Ralimetinib is MAPK14. Ralimetinib reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ralimetinib%" OR LOWER(tradeNames_string) LIKE "%ralimetinib%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_5096', 'drugName': 'Ralimetinib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'MAPK14 (ENSG00000112062)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1394 | Q59 | What is the genetic target of the small molecule drug Mavacamten, and what is its status in clinical trials and FDA approval? | There are 7 genetic targets of the small molecule drug Mavacamten: MYH7, MYH6, MYH7B, MYL3, MYL2, MYL7, and MYL4. Mavacamten reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%mavacamten%" OR LOWER(tradeNames_string) LIKE "%mavacamten%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_1036', 'drugName': 'Mavacamten', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'MYH7 (ENSG00000092054), MYH6 (ENSG00000197616), MYH7B (ENSG00000078814), MYL3 (ENSG00000160808), MYL2 (ENSG00000111245), MYL7 (ENSG00000106631), MYL4 (ENSG00000198336)', 'yearOfFirstApproval... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1783 | Q59 | What is the genetic target of the small molecule drug Decoglurant, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Decoglurant: GRM2 and GRM3. Decoglurant reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%decoglurant%" OR LOWER(tradeNames_string) LIKE "%decoglurant%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_6286', 'drugName': 'Decoglurant', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'GRM2 (ENSG00000164082), GRM3 (ENSG00000198822)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_6287', 'drugName': 'Decoglurant... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1155 | Q59 | What is the genetic target of the small molecule drug Cenicriviroc, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Cenicriviroc: CCR2 and CCR5. Cenicriviroc reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%cenicriviroc%" OR LOWER(tradeNames_string) LIKE "%cenicriviroc%" OR ... | [{'UUID': 'DrugGeneTargets_v2_3740', 'drugName': 'Cenicriviroc', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CCR2 (ENSG00000121807), CCR5 (ENSG00000160791)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_3741', 'drugName': 'Cenicrivir... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1040 | Q59 | What is the genetic target of the antibody drug Fremanezumab, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the antibody drug Fremanezumab: CALCA and CALCB. Fremanezumab reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%fremanezumab%" OR LOWER(tradeNames_string) LIKE "%fremanezumab%" OR ... | [{'UUID': 'DrugGeneTargets_v2_5545', 'drugName': 'Fremanezumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'CALCA (ENSG00000110680), CALCB (ENSG00000175868)', 'yearOfFirstApproval': 2018, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.378 | Q59 | What is the genetic target of the antibody drug Ebdarokimab, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the antibody drug Ebdarokimab: IL12B, IL12A, and IL23A. Ebdarokimab reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ebdarokimab%" OR LOWER(tradeNames_string) LIKE "%ebdarokimab%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_344', 'drugName': 'Ebdarokimab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'IL12B (ENSG00000113302), IL12A (ENSG00000168811), IL23A (ENSG00000110944)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_345', 'drug... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.674 | Q59 | What is the genetic target of the small molecule drug Desloratadine, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Desloratadine is HRH1. Desloratadine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%desloratadine%" OR LOWER(tradeNames_string) LIKE "%desloratadine%" O... | [{'UUID': 'DrugGeneTargets_v2_3239', 'drugName': 'Desloratadine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH1 (ENSG00000196639)', 'yearOfFirstApproval': 2001, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1527 | Q59 | What is the genetic target of the small molecule drug Chlorzoxazone, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Chlorzoxazone is KCNN4. Chlorzoxazone reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%chlorzoxazone%" OR LOWER(tradeNames_string) LIKE "%chlorzoxazone%" O... | [{'UUID': 'DrugGeneTargets_v2_326', 'drugName': 'Chlorzoxazone', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'KCNN4 (ENSG00000104783)', 'yearOfFirstApproval': 1958, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.362 | Q59 | What is the genetic target of the small molecule drug Procyclidine Hydrochloride, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Procyclidine Hydrochloride is CHRM1. Procyclidine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%procyclidine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%proc... | [{'UUID': 'DrugGeneTargets_v2_4919', 'drugName': 'Procyclidine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRM1 (ENSG00000168539)', 'yearOfFirstApproval': 1955, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.976 | Q59 | What is the genetic target of the small molecule drug Levorphanol, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Levorphanol is OPRM1. Levorphanol reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%levorphanol%" OR LOWER(tradeNames_string) LIKE "%levorphanol%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_4300', 'drugName': 'Levorphanol', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'OPRM1 (ENSG00000112038)', 'yearOfFirstApproval': 1991, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_5454', 'drugName': 'Levorphanol Tartrate', 'drugMole... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.790 | Q59 | What is the genetic target of the small molecule drug Cobimetinib Fumarate, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Cobimetinib Fumarate: MAP2K1 and MAP2K2. Cobimetinib Fumarate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%cobimetinib fumarate%" OR LOWER(tradeNames_string) LIKE "%cobimetini... | [{'UUID': 'DrugGeneTargets_v2_6004', 'drugName': 'Cobimetinib Fumarate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'MAP2K1 (ENSG00000169032), MAP2K2 (ENSG00000126934)', 'yearOfFirstApproval': 2015, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_6005', 'drugName... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.742 | Q59 | What is the genetic target of the small molecule drug Selegiline Hydrochloride, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Selegiline Hydrochloride is MAOB. Selegiline Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%selegiline hydrochloride%" OR LOWER(tradeNames_string) LIKE "%selegi... | [{'UUID': 'DrugGeneTargets_v2_991', 'drugName': 'Selegiline Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'MAOB (ENSG00000069535)', 'yearOfFirstApproval': 1989, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1044 | Q59 | What is the genetic target of the small molecule drug Dabigatran Etexilate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Dabigatran Etexilate is F2. Dabigatran Etexilate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%dabigatran etexilate%" OR LOWER(tradeNames_string) LIKE "%dabigatran... | [{'UUID': 'DrugGeneTargets_v2_5711', 'drugName': 'Dabigatran Etexilate Mesylate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'F2 (ENSG00000180210)', 'yearOfFirstApproval': 2010, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_952', 'drugName': 'Dabigatran Etexila... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.979 | Q59 | What is the genetic target of the small molecule drug Arzoxifene, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Arzoxifene: ESR2 and ESR1. Arzoxifene reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%arzoxifene%" OR LOWER(tradeNames_string) LIKE "%arzoxifene%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_645', 'drugName': 'Arzoxifene', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ESR2 (ENSG00000140009), ESR1 (ENSG00000091831)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1526 | Q59 | What is the genetic target of the small molecule drug Doxepin, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Doxepin is SLC6A2. Doxepin reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%doxepin%" OR LOWER(tradeNames_string) LIKE "%doxepin%" OR LOWER(drug... | [{'UUID': 'DrugGeneTargets_v2_2495', 'drugName': 'Doxepin Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A2 (ENSG00000103546)', 'yearOfFirstApproval': 1969, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1761', 'drugName': 'Doxepin', 'drugMolecu... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1488 | Q59 | What is the genetic target of the small molecule drug Brompheniramine Maleate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Brompheniramine Maleate is HRH1. Brompheniramine Maleate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%brompheniramine maleate%" OR LOWER(tradeNames_string) LIKE "%bromphe... | [{'UUID': 'DrugGeneTargets_v2_1014', 'drugName': 'Brompheniramine Maleate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH1 (ENSG00000196639)', 'yearOfFirstApproval': 1957, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_431', 'drugName': 'Dexbrompheniramine Mal... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1525 | Q59 | What is the genetic target of the small molecule drug Ticagrelor, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Ticagrelor is P2RY12. Ticagrelor reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ticagrelor%" OR LOWER(tradeNames_string) LIKE "%ticagrelor%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_4496', 'drugName': 'Ticagrelor', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'P2RY12 (ENSG00000169313)', 'yearOfFirstApproval': 2011, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1492 | Q59 | What is the genetic target of the antibody drug Aducanumab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Aducanumab is APP. Aducanumab reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%aducanumab%" OR LOWER(tradeNames_string) LIKE "%aducanumab%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_4177', 'drugName': 'Aducanumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'APP (ENSG00000142192)', 'yearOfFirstApproval': 2021, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1694 | Q59 | What is the genetic target of the small molecule drug Tecalcet, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Tecalcet is CASR. Tecalcet reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tecalcet%" OR LOWER(tradeNames_string) LIKE "%tecalcet%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_622', 'drugName': 'Tecalcet Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CASR (ENSG00000036828)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_3281', 'drugName': 'Tecalcet', 'drugMolecular... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1716 | Q59 | What is the genetic target of the antibody drug Denosumab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Denosumab is TNFSF11. Denosumab reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%denosumab%" OR LOWER(tradeNames_string) LIKE "%denosumab%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_1723', 'drugName': 'Denosumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'TNFSF11 (ENSG00000120659)', 'yearOfFirstApproval': 2010, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1246 | Q59 | What is the genetic target of the small molecule drug Tranylcypromine, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Tranylcypromine: MAOA and MAOB. Tranylcypromine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tranylcypromine%" OR LOWER(tradeNames_string) LIKE "%tranylcypromine... | [{'UUID': 'DrugGeneTargets_v2_3703', 'drugName': 'Tranylcypromine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'MAOA (ENSG00000189221), MAOB (ENSG00000069535)', 'yearOfFirstApproval': 1961, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1424', 'drugName': 'Trany... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.892 | Q59 | What is the genetic target of the small molecule drug Halobetasol Propionate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Halobetasol Propionate is NR3C1. Halobetasol Propionate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%halobetasol propionate%" OR LOWER(tradeNames_string) LIKE "%halobeta... | [{'UUID': 'DrugGeneTargets_v2_1442', 'drugName': 'Halobetasol Propionate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'NR3C1 (ENSG00000113580)', 'yearOfFirstApproval': 1990, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.82 | Q59 | What is the genetic target of the small molecule drug Sertindole, and what is its status in clinical trials and FDA approval? | There are 6 genetic targets of the small molecule drug Sertindole: HTR2A, HTR2C, ADRA1A, ADRA1D, ADRA1B, and DRD2. Sertindole reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%sertindole%" OR LOWER(tradeNames_string) LIKE "%sertindole%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_5174', 'drugName': 'Sertindole', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR2A (ENSG00000102468), HTR2C (ENSG00000147246), ADRA1A (ENSG00000120907), ADRA1D (ENSG00000171873), ADRA1B (ENSG00000170214), DRD2 (ENSG00000149295)', 'yearOfFirstApproval': 0, 'maxClinica... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1182 | Q59 | What is the genetic target of the small molecule drug Tolazoline Hydrochloride, and what is its status in clinical trials and FDA approval? | There are 8 genetic targets of the small molecule drug Tolazoline Hydrochloride: HRH1, HRH2, ADRA1A, ADRA2A, ADRA2C, ADRA1D, ADRA1B, and ADRA2B. Tolazoline Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tolazoline hydrochloride%" OR LOWER(tradeNames_string) LIKE "%tolazo... | [{'UUID': 'DrugGeneTargets_v2_2553', 'drugName': 'Tolazoline Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH1 (ENSG00000196639), HRH2 (ENSG00000113749), ADRA1A (ENSG00000120907), ADRA2A (ENSG00000150594), ADRA2C (ENSG00000184160), ADRA1D (ENSG00000171873), ADRA1B (ENSG00000170214)... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.821 | Q59 | What is the genetic target of the small molecule drug Crenolanib, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Crenolanib: FLT3, PDGFRB, and PDGFRA. Crenolanib reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%crenolanib%" OR LOWER(tradeNames_string) LIKE "%crenolanib%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_3476', 'drugName': 'Crenolanib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'FLT3 (ENSG00000122025), PDGFRB (ENSG00000113721), PDGFRA (ENSG00000134853)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_3477... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1283 | Q59 | What is the genetic target of the small molecule drug Phenylephrine, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Phenylephrine: ADRA1A, ADRA1D, and ADRA1B. Phenylephrine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%phenylephrine%" OR LOWER(tradeNames_string) LIKE "%phenylephrine%" O... | [{'UUID': 'DrugGeneTargets_v2_6113', 'drugName': 'Phenylephrine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRA1A (ENSG00000120907), ADRA1D (ENSG00000171873), ADRA1B (ENSG00000170214)', 'yearOfFirstApproval': 1952, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.678 | Q59 | What is the genetic target of the small molecule drug Disulfiram, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Disulfiram is ALDH2. Disulfiram reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%disulfiram%" OR LOWER(tradeNames_string) LIKE "%disulfiram%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_5934', 'drugName': 'Disulfiram', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ALDH2 (ENSG00000111275)', 'yearOfFirstApproval': 1951, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1533 | Q59 | What is the genetic target of the small molecule drug Tiotropium, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Tiotropium is CHRM3. Tiotropium reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tiotropium%" OR LOWER(tradeNames_string) LIKE "%tiotropium%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_4878', 'drugName': 'Tiotropium Bromide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRM3 (ENSG00000133019)', 'yearOfFirstApproval': 2004, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_547', 'drugName': 'Tiotropium', 'drugMolecula... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.59 | Q59 | What is the genetic target of the small molecule drug Berotralstat, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Berotralstat is KLKB1. Berotralstat reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%berotralstat%" OR LOWER(tradeNames_string) LIKE "%berotralstat%" OR ... | [{'UUID': 'DrugGeneTargets_v2_1536', 'drugName': 'Berotralstat', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'KLKB1 (ENSG00000164344)', 'yearOfFirstApproval': 2020, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4296', 'drugName': 'Berotralstat Hydrochloride', 'd... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.136 | Q59 | What is the genetic target of the small molecule drug Diltiazem Hydrochloride, and what is its status in clinical trials and FDA approval? | There are 4 genetic targets of the small molecule drug Diltiazem Hydrochloride: CACNA1C, CACNA1S, CACNA1D, and CACNA1F. Diltiazem Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%diltiazem hydrochloride%" OR LOWER(tradeNames_string) LIKE "%diltiaz... | [{'UUID': 'DrugGeneTargets_v2_927', 'drugName': 'Diltiazem Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CACNA1C (ENSG00000151067), CACNA1S (ENSG00000081248), CACNA1D (ENSG00000157388), CACNA1F (ENSG00000102001)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsAppro... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1150 | Q59 | What is the genetic target of the small molecule drug Isopropamide, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Isopropamide: CHRM3 and CHRM1. Isopropamide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%isopropamide%" OR LOWER(tradeNames_string) LIKE "%isopropamide%" OR ... | [{'UUID': 'DrugGeneTargets_v2_3463', 'drugName': 'Isopropamide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRM3 (ENSG00000133019), CHRM1 (ENSG00000168539)', 'yearOfFirstApproval': 1957, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3462', 'drugName': 'Isopro... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.942 | Q59 | What is the genetic target of the small molecule drug Etoposide, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Etoposide: TOP2A and TOP2B. Etoposide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%etoposide%" OR LOWER(tradeNames_string) LIKE "%etoposide%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_2949', 'drugName': 'Etoposide Phosphate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TOP2A (ENSG00000131747)', 'yearOfFirstApproval': 1996, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4763', 'drugName': 'Etoposide', 'drugMolecul... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1685 | Q59 | What is the genetic target of the small molecule drug Avacopan, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Avacopan is C5AR1. Avacopan reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%avacopan%" OR LOWER(tradeNames_string) LIKE "%avacopan%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_5921', 'drugName': 'Avacopan', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'C5AR1 (ENSG00000197405)', 'yearOfFirstApproval': 2021, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.830 | Q59 | What is the genetic target of the small molecule drug Levamlodipine, and what is its status in clinical trials and FDA approval? | There are 4 genetic targets of the small molecule drug Levamlodipine: CACNA1C, CACNA1S, CACNA1D, and CACNA1F. Levamlodipine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%levamlodipine%" OR LOWER(tradeNames_string) LIKE "%levamlodipine%" O... | [{'UUID': 'DrugGeneTargets_v2_4057', 'drugName': 'Levamlodipine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CACNA1C (ENSG00000151067), CACNA1S (ENSG00000081248), CACNA1D (ENSG00000157388), CACNA1F (ENSG00000102001)', 'yearOfFirstApproval': 2019, 'maxClinicalTrialPhase': 4, 'drugIsApproved': Tru... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1224 | Q59 | What is the genetic target of the small molecule drug Doxycycline, and what is its status in clinical trials and FDA approval? | There are 4 genetic targets of the small molecule drug Doxycycline: MMP1, MMP13, MMP8, and MMP7. Doxycycline reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%doxycycline%" OR LOWER(tradeNames_string) LIKE "%doxycycline%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_285', 'drugName': 'Doxycycline Anhydrous', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'MMP13 (ENSG00000137745), MMP8 (ENSG00000118113), MMP7 (ENSG00000137673), MMP1 (ENSG00000196611)', 'yearOfFirstApproval': 1967, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, ... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.510 | Q59 | What is the genetic target of the small molecule drug Ethotoin, and what is its status in clinical trials and FDA approval? | There are 10 genetic targets of the small molecule drug Ethotoin: SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. Ethotoin reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ethotoin%" OR LOWER(tradeNames_string) LIKE "%ethotoin%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_2992', 'drugName': 'Ethotoin', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SCN1A (ENSG00000144285), SCN5A (ENSG00000183873), SCN4A (ENSG00000007314), SCN7A (ENSG00000136546), SCN2A (ENSG00000136531), SCN9A (ENSG00000169432), SCN3A (ENSG00000153253), SCN11A (ENSG00000... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1776 | Q59 | What is the genetic target of the antibody drug Pertuzumab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Pertuzumab is ERBB2. Pertuzumab reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%pertuzumab%" OR LOWER(tradeNames_string) LIKE "%pertuzumab%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_1613', 'drugName': 'Pertuzumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'ERBB2 (ENSG00000141736)', 'yearOfFirstApproval': 2012, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.351 | Q59 | What is the genetic target of the small molecule drug Imiquimod, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Imiquimod is TLR7. Imiquimod reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%imiquimod%" OR LOWER(tradeNames_string) LIKE "%imiquimod%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_1394', 'drugName': 'Imiquimod', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TLR7 (ENSG00000196664)', 'yearOfFirstApproval': 1997, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.392 | Q59 | What is the genetic target of the small molecule drug Bardoxolone Methyl, and what is its status in clinical trials and FDA approval? | There are 4 genetic targets of the small molecule drug Bardoxolone Methyl: NFE2L2, KEAP1, PPARG, and IKBKB. Bardoxolone Methyl reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%bardoxolone methyl%" OR LOWER(tradeNames_string) LIKE "%bardoxolone ... | [{'UUID': 'DrugGeneTargets_v2_4920', 'drugName': 'Bardoxolone Methyl', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'NFE2L2 (ENSG00000116044), KEAP1 (ENSG00000079999), PPARG (ENSG00000132170), IKBKB (ENSG00000104365)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}, ... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1033 | Q59 | What is the genetic target of the small molecule drug Levorphanol Tartrate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Levorphanol Tartrate is OPRM1. Levorphanol Tartrate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%levorphanol tartrate%" OR LOWER(tradeNames_string) LIKE "%levorphano... | [{'UUID': 'DrugGeneTargets_v2_5454', 'drugName': 'Levorphanol Tartrate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'OPRM1 (ENSG00000112038)', 'yearOfFirstApproval': 1991, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.901 | Q59 | What is the genetic target of the small molecule drug Lusutrombopag, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Lusutrombopag is MPL. Lusutrombopag reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%lusutrombopag%" OR LOWER(tradeNames_string) LIKE "%lusutrombopag%" O... | [{'UUID': 'DrugGeneTargets_v2_362', 'drugName': 'Lusutrombopag', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'MPL (ENSG00000117400)', 'yearOfFirstApproval': 2018, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.835 | Q59 | What is the genetic target of the small molecule drug Thiothixene Hydrochloride, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Thiothixene Hydrochloride: HTR2A and DRD2. Thiothixene Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%thiothixene hydrochloride%" OR LOWER(tradeNames_string) LIKE "%thiot... | [{'UUID': 'DrugGeneTargets_v2_2207', 'drugName': 'Thiothixene Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR2A (ENSG00000102468), DRD2 (ENSG00000149295)', 'yearOfFirstApproval': 1970, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2208', 'drugNa... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1894 | Q59 | What is the genetic target of the small molecule drug Panulisib, and what is its status in clinical trials and FDA approval? | There are 10 genetic targets of the small molecule drug Panulisib: ACVRL1, MTOR, PIK3R1, PIK3CB, PIK3CG, PIK3CA, PIK3R2, PIK3CD, PIK3R5, and PIK3R3. Panulisib reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%panulisib%" OR LOWER(tradeNames_string) LIKE "%panulisib%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_2425', 'drugName': 'Panulisib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ACVRL1 (ENSG00000139567), MTOR (ENSG00000198793), PIK3R1 (ENSG00000145675), PIK3CB (ENSG00000051382), PIK3CG (ENSG00000105851), PIK3CA (ENSG00000121879), PIK3R2 (ENSG00000105647), PIK3CD (ENS... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.481 | Q59 | What is the genetic target of the small molecule drug Krn-633, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Krn-633: FLT1, FLT4, and KDR. Krn-633 reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%krn-633%" OR LOWER(tradeNames_string) LIKE "%krn-633%" OR LOWER(drug... | [{'UUID': 'DrugGeneTargets_v2_2095', 'drugName': 'Krn-633', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'FLT1 (ENSG00000102755), FLT4 (ENSG00000037280), KDR (ENSG00000128052)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1472 | Q59 | What is the genetic target of the antibody drug Frovocimab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Frovocimab is PCSK9. Frovocimab reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%frovocimab%" OR LOWER(tradeNames_string) LIKE "%frovocimab%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_4159', 'drugName': 'Frovocimab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'PCSK9 (ENSG00000169174)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1887 | Q59 | What is the genetic target of the antibody drug Ravulizumab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Ravulizumab is C5. Ravulizumab reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ravulizumab%" OR LOWER(tradeNames_string) LIKE "%ravulizumab%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_629', 'drugName': 'Ravulizumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'C5 (ENSG00000106804)', 'yearOfFirstApproval': 2018, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1398 | Q59 | What is the genetic target of the small molecule drug Triflupromazine, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Triflupromazine is DRD2. Triflupromazine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%triflupromazine%" OR LOWER(tradeNames_string) LIKE "%triflupromazine... | [{'UUID': 'DrugGeneTargets_v2_203', 'drugName': 'Triflupromazine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DRD2 (ENSG00000149295)', 'yearOfFirstApproval': 1957, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4009', 'drugName': 'Triflupromazine Hydrochloride'... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.659 | Q59 | What is the genetic target of the oligosaccharide drug Dalteparin Sodium, and what is its status in clinical trials and FDA approval? | The genetic target of the oligosaccharide drug Dalteparin Sodium is SERPINC1. Dalteparin Sodium reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%dalteparin sodium%" OR LOWER(tradeNames_string) LIKE "%dalteparin so... | [{'UUID': 'DrugGeneTargets_v2_204', 'drugName': 'Dalteparin Sodium', 'drugMolecularType': 'Oligosaccharide', 'newLinkedTargets_string': 'SERPINC1 (ENSG00000117601)', 'yearOfFirstApproval': 1994, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.175 | Q59 | What is the genetic target of the small molecule drug Tocainide, and what is its status in clinical trials and FDA approval? | There are 10 genetic targets of the small molecule drug Tocainide: SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. Tocainide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tocainide%" OR LOWER(tradeNames_string) LIKE "%tocainide%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_5269', 'drugName': 'Tocainide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SCN1A (ENSG00000144285), SCN5A (ENSG00000183873), SCN4A (ENSG00000007314), SCN7A (ENSG00000136546), SCN2A (ENSG00000136531), SCN9A (ENSG00000169432), SCN3A (ENSG00000153253), SCN11A (ENSG0000... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
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