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Q59.1159
Q59
What is the genetic target of the small molecule drug Suprofen, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Suprofen: PTGS2 and PTGS1. Suprofen reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%suprofen%" OR LOWER(tradeNames_string) LIKE "%suprofen%" OR LOWER(dr...
[{'UUID': 'DrugGeneTargets_v2_792', 'drugName': 'Suprofen', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGS2 (ENSG00000073756), PTGS1 (ENSG00000095303)', 'yearOfFirstApproval': 1985, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.39
Q59
What is the genetic target of the small molecule drug Aripiprazole Lauroxil, and what is its status in clinical trials and FDA approval?
There are 3 genetic targets of the small molecule drug Aripiprazole Lauroxil: DRD2, HTR2A, and HTR1A. Aripiprazole Lauroxil reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%aripiprazole lauroxil%" OR LOWER(tradeNames_string) LIKE "%aripipraz...
[{'UUID': 'DrugGeneTargets_v2_4679', 'drugName': 'Aripiprazole Lauroxil', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DRD2 (ENSG00000149295), HTR2A (ENSG00000102468), HTR1A (ENSG00000178394)', 'yearOfFirstApproval': 2015, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTarg...
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Q59.720
Q59
What is the genetic target of the small molecule drug Ergotamine Tartrate, and what is its status in clinical trials and FDA approval?
There are 7 genetic targets of the small molecule drug Ergotamine Tartrate: ADRA1A, ADRA2A, ADRA2C, ADRA1D, ADRA1B, ADRA2B, and HTR1D. Ergotamine Tartrate reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%ergotamine tartrate%" OR LOWER(tradeNames_string) LIKE "%ergotamine ...
[{'UUID': 'DrugGeneTargets_v2_3552', 'drugName': 'Ergotamine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR1D (ENSG00000179546), ADRA1A (ENSG00000120907), ADRA2A (ENSG00000150594), ADRA2C (ENSG00000184160), ADRA1D (ENSG00000171873), ADRA1B (ENSG00000170214), ADRA2B (ENSG00000274286)', 'yearOfF...
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Q59.93
Q59
What is the genetic target of the small molecule drug Bezafibrate, and what is its status in clinical trials and FDA approval?
There are 3 genetic targets of the small molecule drug Bezafibrate: PPARG, PPARA, and PPARD. Bezafibrate reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%bezafibrate%" OR LOWER(tradeNames_string) LIKE "%bezafibrate%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_1564', 'drugName': 'Bezafibrate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PPARG (ENSG00000132170), PPARA (ENSG00000186951), PPARD (ENSG00000112033)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1937
Q59
What is the genetic target of the antibody drug Eculizumab, and what is its status in clinical trials and FDA approval?
The genetic target of the antibody drug Eculizumab is C5. Eculizumab reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%eculizumab%" OR LOWER(tradeNames_string) LIKE "%eculizumab%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_844', 'drugName': 'Eculizumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'C5 (ENSG00000106804)', 'yearOfFirstApproval': 2007, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1215
Q59
What is the genetic target of the small molecule drug Bismuth Subgallate, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Bismuth Subgallate is F12. Bismuth Subgallate reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%bismuth subgallate%" OR LOWER(tradeNames_string) LIKE "%bismuth subg...
[{'UUID': 'DrugGeneTargets_v2_5123', 'drugName': 'Bismuth Subgallate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'F12 (ENSG00000131187)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.882
Q59
What is the genetic target of the small molecule drug Ubrogepant, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Ubrogepant is CALCRL. Ubrogepant reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%ubrogepant%" OR LOWER(tradeNames_string) LIKE "%ubrogepant%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_528', 'drugName': 'Ubrogepant', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CALCRL (ENSG00000064989)', 'yearOfFirstApproval': 2019, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1353
Q59
What is the genetic target of the small molecule drug Allopurinol Sodium, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Allopurinol Sodium is XDH. Allopurinol Sodium reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%allopurinol sodium%" OR LOWER(tradeNames_string) LIKE "%allopurinol ...
[{'UUID': 'DrugGeneTargets_v2_3457', 'drugName': 'Allopurinol Sodium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'XDH (ENSG00000158125)', 'yearOfFirstApproval': 1996, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1891
Q59
What is the genetic target of the antibody drug Az9773, and what is its status in clinical trials and FDA approval?
The genetic target of the antibody drug Az9773 is TNF. Az9773 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%az9773%" OR LOWER(tradeNames_string) LIKE "%az9773%" OR LOWER(drugSy...
[{'UUID': 'DrugGeneTargets_v2_3954', 'drugName': 'Az9773', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'TNF (ENSG00000232810)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}]
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Q59.1102
Q59
What is the genetic target of the small molecule drug Bms-754807, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Bms-754807: IGF1R and INSR. Bms-754807 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%bms-754807%" OR LOWER(tradeNames_string) LIKE "%bms-754807%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_1288', 'drugName': 'Bms-754807', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'IGF1R (ENSG00000140443), INSR (ENSG00000171105)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_1289', 'drugName': 'Bms-754807'...
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Q59.1165
Q59
What is the genetic target of the antibody drug Imc-Eb10, and what is its status in clinical trials and FDA approval?
The genetic target of the antibody drug Imc-Eb10 is FLT3. Imc-Eb10 reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%imc-eb10%" OR LOWER(tradeNames_string) LIKE "%imc-eb10%" OR LOWER(dr...
[{'UUID': 'DrugGeneTargets_v2_1054', 'drugName': 'Imc-Eb10', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'FLT3 (ENSG00000122025)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}]
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Q59.1365
Q59
What is the genetic target of the small molecule drug Almotriptan, and what is its status in clinical trials and FDA approval?
There are 3 genetic targets of the small molecule drug Almotriptan: HTR1F, HTR1D, and HTR1B. Almotriptan reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%almotriptan%" OR LOWER(tradeNames_string) LIKE "%almotriptan%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_3460', 'drugName': 'Almotriptan Malate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR1F (ENSG00000179097), HTR1D (ENSG00000179546), HTR1B (ENSG00000135312)', 'yearOfFirstApproval': 2001, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTarget...
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Q59.1959
Q59
What is the genetic target of the small molecule drug Deslanoside, and what is its status in clinical trials and FDA approval?
There are 8 genetic targets of the small molecule drug Deslanoside: ATP1A1, ATP1B2, ATP1B1, ATP1A2, ATP1B3, ATP1A3, ATP1A4, and FXYD2. Deslanoside reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%deslanoside%" OR LOWER(tradeNames_string) LIKE "%deslanoside%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_1509', 'drugName': 'Deslanoside', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ATP1A1 (ENSG00000163399), ATP1B2 (ENSG00000129244), ATP1B1 (ENSG00000143153), ATP1A2 (ENSG00000018625), ATP1B3 (ENSG00000069849), ATP1A3 (ENSG00000105409), ATP1A4 (ENSG00000132681), FXYD2 (...
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Q59.505
Q59
What is the genetic target of the small molecule drug Ttp-607, and what is its status in clinical trials and FDA approval?
There are 3 genetic targets of the small molecule drug Ttp-607: AURKB, AURKC, and AURKA. Ttp-607 reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%ttp-607%" OR LOWER(tradeNames_string) LIKE "%ttp-607%" OR LOWER(drug...
[{'UUID': 'DrugGeneTargets_v2_4902', 'drugName': 'Ttp-607', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'AURKB (ENSG00000178999), AURKC (ENSG00000105146), AURKA (ENSG00000087586)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}]
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Q59.342
Q59
What is the genetic target of the small molecule drug Encorafenib, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Encorafenib is BRAF. Encorafenib reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%encorafenib%" OR LOWER(tradeNames_string) LIKE "%encorafenib%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_3616', 'drugName': 'Encorafenib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'BRAF (ENSG00000157764)', 'yearOfFirstApproval': 2018, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1198
Q59
What is the genetic target of the small molecule drug Clidinium Bromide, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Clidinium Bromide: CHRM3 and CHRM1. Clidinium Bromide reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%clidinium bromide%" OR LOWER(tradeNames_string) LIKE "%clidinium bro...
[{'UUID': 'DrugGeneTargets_v2_5459', 'drugName': 'Umeclidinium Bromide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRM3 (ENSG00000133019)', 'yearOfFirstApproval': 2013, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_6136', 'drugName': 'Aclidinium Bromide', 'd...
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Q59.29
Q59
What is the genetic target of the small molecule drug Prednisolone Phosphoric Acid, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Prednisolone Phosphoric Acid is NR3C1. Prednisolone Phosphoric Acid reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%prednisolone phosphoric acid%" OR LOWER(tradeNames_string) LIKE "%pr...
[{'UUID': 'DrugGeneTargets_v2_5936', 'drugName': 'Prednisolone Phosphoric Acid', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'NR3C1 (ENSG00000113580)', 'yearOfFirstApproval': 1973, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1227
Q59
What is the genetic target of the small molecule drug Neostigmine, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Neostigmine is ACHE. Neostigmine reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%neostigmine%" OR LOWER(tradeNames_string) LIKE "%neostigmine%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_6228', 'drugName': 'Neostigmine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ACHE (ENSG00000087085)', 'yearOfFirstApproval': 2013, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1766', 'drugName': 'Neostigmine Methylsulfate', 'drug...
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Q59.1434
Q59
What is the genetic target of the small molecule drug Enobosarm, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Enobosarm is AR. Enobosarm reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%enobosarm%" OR LOWER(tradeNames_string) LIKE "%enobosarm%" OR LOWER(...
[{'UUID': 'DrugGeneTargets_v2_1611', 'drugName': 'Enobosarm', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'AR (ENSG00000169083)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}]
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Q59.1954
Q59
What is the genetic target of the small molecule drug Minopafant, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Minopafant is PTAFR. Minopafant reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%minopafant%" OR LOWER(tradeNames_string) LIKE "%minopafant%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_2350', 'drugName': 'Minopafant', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTAFR (ENSG00000169403)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}]
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Q59.954
Q59
What is the genetic target of the small molecule drug Hydroxyprogesterone Caproate, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Hydroxyprogesterone Caproate is PGR. Hydroxyprogesterone Caproate reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%hydroxyprogesterone caproate%" OR LOWER(tradeNames_string) LIKE "%hy...
[{'UUID': 'DrugGeneTargets_v2_4832', 'drugName': 'Hydroxyprogesterone Caproate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PGR (ENSG00000082175)', 'yearOfFirstApproval': 1975, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.172
Q59
What is the genetic target of the small molecule drug Brimonidine Tartrate, and what is its status in clinical trials and FDA approval?
There are 3 genetic targets of the small molecule drug Brimonidine Tartrate: ADRA2A, ADRA2C, and ADRA2B. Brimonidine Tartrate reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%brimonidine tartrate%" OR LOWER(tradeNames_string) LIKE "%brimonidin...
[{'UUID': 'DrugGeneTargets_v2_4923', 'drugName': 'Brimonidine Tartrate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRA2A (ENSG00000150594), ADRA2C (ENSG00000184160), ADRA2B (ENSG00000274286)', 'yearOfFirstApproval': 1996, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1406
Q59
What is the genetic target of the small molecule drug Ly2881835, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Ly2881835 is FFAR1. Ly2881835 reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%ly2881835%" OR LOWER(tradeNames_string) LIKE "%ly2881835%" OR LOWER(...
[{'UUID': 'DrugGeneTargets_v2_5831', 'drugName': 'Ly2881835', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'FFAR1 (ENSG00000126266)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}]
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Q59.1207
Q59
What is the genetic target of the small molecule drug Perhexiline, and what is its status in clinical trials and FDA approval?
There are 3 genetic targets of the small molecule drug Perhexiline: MTOR, CPT2, and CPT1B. Perhexiline reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%perhexiline%" OR LOWER(tradeNames_string) LIKE "%perhexiline%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_1726', 'drugName': 'Perhexiline Maleate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'MTOR (ENSG00000198793), CPT2 (ENSG00000157184), CPT1B (ENSG00000205560)', 'yearOfFirstApproval': 1974, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets...
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Q59.1263
Q59
What is the genetic target of the small molecule drug Moxisylyte, and what is its status in clinical trials and FDA approval?
There are 6 genetic targets of the small molecule drug Moxisylyte: ADRA1A, ADRA2A, ADRA2C, ADRA1D, ADRA1B, and ADRA2B. Moxisylyte reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%moxisylyte%" OR LOWER(tradeNames_string) LIKE "%moxisylyte%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_770', 'drugName': 'Moxisylyte', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRA1A (ENSG00000120907), ADRA2A (ENSG00000150594), ADRA2C (ENSG00000184160), ADRA1D (ENSG00000171873), ADRA1B (ENSG00000170214), ADRA2B (ENSG00000274286)', 'yearOfFirstApproval': 0, 'maxClin...
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Q59.1400
Q59
What is the genetic target of the small molecule drug Febuxostat, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Febuxostat is XDH. Febuxostat reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%febuxostat%" OR LOWER(tradeNames_string) LIKE "%febuxostat%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_1230', 'drugName': 'Febuxostat', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'XDH (ENSG00000158125)', 'yearOfFirstApproval': 2009, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.920
Q59
What is the genetic target of the small molecule drug Leq506, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Leq506 is SMO. Leq506 reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%leq506%" OR LOWER(tradeNames_string) LIKE "%leq506%" OR LOWER(drugSy...
[{'UUID': 'DrugGeneTargets_v2_688', 'drugName': 'Leq506', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SMO (ENSG00000128602)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}]
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Q59.497
Q59
What is the genetic target of the antibody drug Spesolimab, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the antibody drug Spesolimab: IL1RL2 and IL1RAP. Spesolimab reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%spesolimab%" OR LOWER(tradeNames_string) LIKE "%spesolimab%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_2421', 'drugName': 'Spesolimab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'IL1RL2 (ENSG00000115598), IL1RAP (ENSG00000196083)', 'yearOfFirstApproval': 2022, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.962
Q59
What is the genetic target of the small molecule drug Ethacrynic Acid, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Ethacrynic Acid is SLC12A1. Ethacrynic Acid reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%ethacrynic acid%" OR LOWER(tradeNames_string) LIKE "%ethacrynic acid...
[{'UUID': 'DrugGeneTargets_v2_3791', 'drugName': 'Ethacrynic Acid', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC12A1 (ENSG00000074803)', 'yearOfFirstApproval': 1967, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3044', 'drugName': 'Ethacrynate Sodium', 'drug...
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Q59.1106
Q59
What is the genetic target of the small molecule drug Spirapril, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Spirapril is ACE. Spirapril reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%spirapril%" OR LOWER(tradeNames_string) LIKE "%spirapril%" OR LOWER(...
[{'UUID': 'DrugGeneTargets_v2_2773', 'drugName': 'Spirapril', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ACE (ENSG00000159640)', 'yearOfFirstApproval': 1994, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4466', 'drugName': 'Spirapril Hydrochloride', 'drugMolec...
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Q59.1041
Q59
What is the genetic target of the small molecule drug Glyburide, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Glyburide: KCNJ11 and ABCC8. Glyburide reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%glyburide%" OR LOWER(tradeNames_string) LIKE "%glyburide%" OR LOWER(...
[{'UUID': 'DrugGeneTargets_v2_934', 'drugName': 'Glyburide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'KCNJ11 (ENSG00000187486), ABCC8 (ENSG00000006071)', 'yearOfFirstApproval': 1984, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.594
Q59
What is the genetic target of the small molecule drug Lansoprazole, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Lansoprazole: ATP4A and ATP4B. Lansoprazole reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%lansoprazole%" OR LOWER(tradeNames_string) LIKE "%lansoprazole%" OR ...
[{'UUID': 'DrugGeneTargets_v2_2720', 'drugName': 'Lansoprazole', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ATP4A (ENSG00000105675), ATP4B (ENSG00000186009)', 'yearOfFirstApproval': 1995, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_908', 'drugName': 'Dexlans...
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Q59.757
Q59
What is the genetic target of the protein drug Leuprolide Mesylate, and what is its status in clinical trials and FDA approval?
The genetic target of the protein drug Leuprolide Mesylate is GNRHR. Leuprolide Mesylate reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%leuprolide mesylate%" OR LOWER(tradeNames_string) LIKE "%leuprolide ...
[{'UUID': 'DrugGeneTargets_v2_483', 'drugName': 'Leuprolide Mesylate', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'GNRHR (ENSG00000109163)', 'yearOfFirstApproval': 2021, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.664
Q59
What is the genetic target of the small molecule drug Doxacurium, and what is its status in clinical trials and FDA approval?
There are 5 genetic targets of the small molecule drug Doxacurium: CHRNA1, CHRNG, CHRNB1, CHRND, and CHRNE. Doxacurium reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%doxacurium%" OR LOWER(tradeNames_string) LIKE "%doxacurium%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_4981', 'drugName': 'Doxacurium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRNA1 (ENSG00000138435), CHRNG (ENSG00000196811), CHRNB1 (ENSG00000170175), CHRND (ENSG00000135902), CHRNE (ENSG00000108556)', 'yearOfFirstApproval': 1991, 'maxClinicalTrialPhase': 4, 'drug...
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Q59.237
Q59
What is the genetic target of the small molecule drug Tetrahydrozoline Hydrochloride, and what is its status in clinical trials and FDA approval?
There are 6 genetic targets of the small molecule drug Tetrahydrozoline Hydrochloride: ADRA1A, ADRA2A, ADRA2C, ADRA1D, ADRA1B, and ADRA2B. Tetrahydrozoline Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%tetrahydrozoline hydrochloride%" OR LOWER(tradeNames_string) LIKE "%...
[{'UUID': 'DrugGeneTargets_v2_1295', 'drugName': 'Tetrahydrozoline Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRA1A (ENSG00000120907), ADRA2A (ENSG00000150594), ADRA2C (ENSG00000184160), ADRA1D (ENSG00000171873), ADRA1B (ENSG00000170214), ADRA2B (ENSG00000274286)', 'yearOfFirstA...
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Q59.739
Q59
What is the genetic target of the small molecule drug Pindolol, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Pindolol: ADRB1 and ADRB2. Pindolol reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%pindolol%" OR LOWER(tradeNames_string) LIKE "%pindolol%" OR LOWER(dr...
[{'UUID': 'DrugGeneTargets_v2_4457', 'drugName': 'Pindolol', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRB1 (ENSG00000043591), ADRB2 (ENSG00000169252)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4458', 'drugName': 'Pindolol',...
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Q59.1989
Q59
What is the genetic target of the small molecule drug Methyltestosterone, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Methyltestosterone is AR. Methyltestosterone reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%methyltestosterone%" OR LOWER(tradeNames_string) LIKE "%methyltestos...
[{'UUID': 'DrugGeneTargets_v2_2216', 'drugName': 'Methyltestosterone', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'AR (ENSG00000169083)', 'yearOfFirstApproval': 1973, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1633
Q59
What is the genetic target of the small molecule drug Cangrelor Tetrasodium, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Cangrelor Tetrasodium is P2RY12. Cangrelor Tetrasodium reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%cangrelor tetrasodium%" OR LOWER(tradeNames_string) LIKE "%cangrelor...
[{'UUID': 'DrugGeneTargets_v2_1075', 'drugName': 'Cangrelor Tetrasodium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'P2RY12 (ENSG00000169313)', 'yearOfFirstApproval': 2015, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1166
Q59
What is the genetic target of the small molecule drug Mepenzolate, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Mepenzolate: CHRM3 and CHRM1. Mepenzolate reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%mepenzolate%" OR LOWER(tradeNames_string) LIKE "%mepenzolate%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_3596', 'drugName': 'Mepenzolate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRM3 (ENSG00000133019), CHRM1 (ENSG00000168539)', 'yearOfFirstApproval': 1956, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3595', 'drugName': 'Mepenzo...
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Q59.1471
Q59
What is the genetic target of the antibody drug Gevokizumab, and what is its status in clinical trials and FDA approval?
The genetic target of the antibody drug Gevokizumab is IL1B. Gevokizumab reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%gevokizumab%" OR LOWER(tradeNames_string) LIKE "%gevokizumab%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_4946', 'drugName': 'Gevokizumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'IL1B (ENSG00000125538)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}]
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Q59.1913
Q59
What is the genetic target of the small molecule drug Ivabradine, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Ivabradine is HCN4. Ivabradine reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%ivabradine%" OR LOWER(tradeNames_string) LIKE "%ivabradine%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_32', 'drugName': 'Ivabradine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HCN4 (ENSG00000138622)', 'yearOfFirstApproval': 2015, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1183', 'drugName': 'Ivabradine Hydrochloride', 'drugMole...
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Q59.1628
Q59
What is the genetic target of the small molecule drug Merimepodib, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Merimepodib is IMPDH1. Merimepodib reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%merimepodib%" OR LOWER(tradeNames_string) LIKE "%merimepodib%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_4814', 'drugName': 'Merimepodib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'IMPDH1 (ENSG00000106348)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}]
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Q59.943
Q59
What is the genetic target of the protein drug Bulevirtide, and what is its status in clinical trials and FDA approval?
The genetic target of the protein drug Bulevirtide is SLC10A1. Bulevirtide reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%bulevirtide%" OR LOWER(tradeNames_string) LIKE "%bulevirtide%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_1428', 'drugName': 'Bulevirtide', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'SLC10A1 (ENSG00000100652)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1219
Q59
What is the genetic target of the small molecule drug Ospemifene, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Ospemifene: ESR2 and ESR1. Ospemifene reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%ospemifene%" OR LOWER(tradeNames_string) LIKE "%ospemifene%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_3057', 'drugName': 'Ospemifene', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ESR2 (ENSG00000140009), ESR1 (ENSG00000091831)', 'yearOfFirstApproval': 2013, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1074
Q59
What is the genetic target of the small molecule drug Zucapsaicin, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Zucapsaicin is TRPV1. Zucapsaicin reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%zucapsaicin%" OR LOWER(tradeNames_string) LIKE "%zucapsaicin%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_366', 'drugName': 'Zucapsaicin', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TRPV1 (ENSG00000196689)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}]
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Q59.111
Q59
What is the genetic target of the small molecule drug Methsuximide, and what is its status in clinical trials and FDA approval?
There are 3 genetic targets of the small molecule drug Methsuximide: CACNA1H, CACNA1G, and CACNA1I. Methsuximide reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%methsuximide%" OR LOWER(tradeNames_string) LIKE "%methsuximide%" OR ...
[{'UUID': 'DrugGeneTargets_v2_4085', 'drugName': 'Methsuximide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CACNA1H (ENSG00000196557), CACNA1G (ENSG00000006283), CACNA1I (ENSG00000100346)', 'yearOfFirstApproval': 1957, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1944
Q59
What is the genetic target of the oligonucleotide drug Tofersen, and what is its status in clinical trials and FDA approval?
The genetic target of the oligonucleotide drug Tofersen is SOD1. Tofersen reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%tofersen%" OR LOWER(tradeNames_string) LIKE "%tofersen%" OR LOWER(dr...
[{'UUID': 'DrugGeneTargets_v2_651', 'drugName': 'Tofersen', 'drugMolecularType': 'Oligonucleotide', 'newLinkedTargets_string': 'SOD1 (ENSG00000142168)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}]
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Q59.574
Q59
What is the genetic target of the small molecule drug Ergocalciferol, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Ergocalciferol is VDR. Ergocalciferol reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%ergocalciferol%" OR LOWER(tradeNames_string) LIKE "%ergocalciferol%"...
[{'UUID': 'DrugGeneTargets_v2_356', 'drugName': 'Ergocalciferol', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'VDR (ENSG00000111424)', 'yearOfFirstApproval': 1941, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4241', 'drugName': 'Doxercalciferol', 'drugMolecular...
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Q59.1177
Q59
What is the genetic target of the small molecule drug Mk-1029, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Mk-1029 is PTGDR2. Mk-1029 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%mk-1029%" OR LOWER(tradeNames_string) LIKE "%mk-1029%" OR LOWER(drug...
[{'UUID': 'DrugGeneTargets_v2_6289', 'drugName': 'Mk-1029', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGDR2 (ENSG00000183134)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}]
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Q59.1184
Q59
What is the genetic target of the small molecule drug Tepotinib, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Tepotinib is MET. Tepotinib reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%tepotinib%" OR LOWER(tradeNames_string) LIKE "%tepotinib%" OR LOWER(...
[{'UUID': 'DrugGeneTargets_v2_1379', 'drugName': 'Tepotinib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'MET (ENSG00000105976)', 'yearOfFirstApproval': 2021, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1908', 'drugName': 'Tepotinib Hydrochloride', 'drugMolec...
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Q59.897
Q59
What is the genetic target of the small molecule drug Masitinib, and what is its status in clinical trials and FDA approval?
There are 4 genetic targets of the small molecule drug Masitinib: KIT, PDGFRB, PDGFRA, and FGFR3. Masitinib reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%masitinib%" OR LOWER(tradeNames_string) LIKE "%masitinib%" OR LOWER(...
[{'UUID': 'DrugGeneTargets_v2_4752', 'drugName': 'Masitinib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'KIT (ENSG00000157404), PDGFRB (ENSG00000113721), PDGFRA (ENSG00000134853), FGFR3 (ENSG00000068078)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'D...
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Q59.956
Q59
What is the genetic target of the small molecule drug Imatinib Mesylate, and what is its status in clinical trials and FDA approval?
There are 4 genetic targets of the small molecule drug Imatinib Mesylate: ABL1, PDGFRB, KIT, and BCR. Imatinib Mesylate reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%imatinib mesylate%" OR LOWER(tradeNames_string) LIKE "%imatinib mesy...
[{'UUID': 'DrugGeneTargets_v2_3270', 'drugName': 'Imatinib Mesylate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ABL1 (ENSG00000097007), PDGFRB (ENSG00000113721), KIT (ENSG00000157404), BCR (ENSG00000186716)', 'yearOfFirstApproval': 2001, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UU...
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Q59.1057
Q59
What is the genetic target of the antibody drug Rg-7652, and what is its status in clinical trials and FDA approval?
The genetic target of the antibody drug Rg-7652 is PCSK9. Rg-7652 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%rg-7652%" OR LOWER(tradeNames_string) LIKE "%rg-7652%" OR LOWER(drug...
[{'UUID': 'DrugGeneTargets_v2_1023', 'drugName': 'Rg-7652', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'PCSK9 (ENSG00000169174)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}]
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Q59.1354
Q59
What is the genetic target of the small molecule drug Paroxetine, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Paroxetine is SLC6A4. Paroxetine reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%paroxetine%" OR LOWER(tradeNames_string) LIKE "%paroxetine%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_4720', 'drugName': 'Paroxetine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A4 (ENSG00000108576)', 'yearOfFirstApproval': 1992, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_5200', 'drugName': 'Paroxetine', 'drug...
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Q59.1373
Q59
What is the genetic target of the small molecule drug Sonidegib, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Sonidegib is SMO. Sonidegib reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%sonidegib%" OR LOWER(tradeNames_string) LIKE "%sonidegib%" OR LOWER(...
[{'UUID': 'DrugGeneTargets_v2_3128', 'drugName': 'Sonidegib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SMO (ENSG00000128602)', 'yearOfFirstApproval': 2015, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3933', 'drugName': 'Sonidegib Phosphate', 'drugMolecular...
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Q59.1448
Q59
What is the genetic target of the small molecule drug Imarikiren Hydrochloride, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Imarikiren Hydrochloride is REN. Imarikiren Hydrochloride reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%imarikiren hydrochloride%" OR LOWER(tradeNames_string) LIKE "%imarik...
[{'UUID': 'DrugGeneTargets_v2_3903', 'drugName': 'Imarikiren Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'REN (ENSG00000143839)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}]
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Q59.891
Q59
What is the genetic target of the small molecule drug Orvepitant, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Orvepitant is TACR1. Orvepitant reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%orvepitant%" OR LOWER(tradeNames_string) LIKE "%orvepitant%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_2045', 'drugName': 'Orvepitant', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TACR1 (ENSG00000115353)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}]
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Q59.1673
Q59
What is the genetic target of the small molecule drug Verubecestat, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Verubecestat is BACE1. Verubecestat reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%verubecestat%" OR LOWER(tradeNames_string) LIKE "%verubecestat%" OR ...
[{'UUID': 'DrugGeneTargets_v2_724', 'drugName': 'Verubecestat', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'BACE1 (ENSG00000186318)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}]
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Q59.857
Q59
What is the genetic target of the small molecule drug Ave0847, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Ave0847: PPARD and PPARG. Ave0847 reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%ave0847%" OR LOWER(tradeNames_string) LIKE "%ave0847%" OR LOWER(drug...
[{'UUID': 'DrugGeneTargets_v2_729', 'drugName': 'Ave0847', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PPARD (ENSG00000112033), PPARG (ENSG00000132170)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_730', 'drugName': 'Ave0847', 'drug...
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Q59.741
Q59
What is the genetic target of the small molecule drug Ziprasidone, and what is its status in clinical trials and FDA approval?
There are 3 genetic targets of the small molecule drug Ziprasidone: HTR2A, DRD2, and HTR2C. Ziprasidone reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%ziprasidone%" OR LOWER(tradeNames_string) LIKE "%ziprasidone%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_1685', 'drugName': 'Ziprasidone', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR2A (ENSG00000102468), DRD2 (ENSG00000149295), HTR2C (ENSG00000147246)', 'yearOfFirstApproval': 2001, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_428...
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Q59.724
Q59
What is the genetic target of the antibody drug Quetmolimab, and what is its status in clinical trials and FDA approval?
The genetic target of the antibody drug Quetmolimab is CX3CL1. Quetmolimab reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%quetmolimab%" OR LOWER(tradeNames_string) LIKE "%quetmolimab%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_537', 'drugName': 'Quetmolimab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'CX3CL1 (ENSG00000006210)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}]
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Q59.460
Q59
What is the genetic target of the small molecule drug Tetracaine, and what is its status in clinical trials and FDA approval?
There are 10 genetic targets of the small molecule drug Tetracaine: SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. Tetracaine reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%tetracaine%" OR LOWER(tradeNames_string) LIKE "%tetracaine%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_5460', 'drugName': 'Tetracaine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SCN1A (ENSG00000144285), SCN5A (ENSG00000183873), SCN4A (ENSG00000007314), SCN7A (ENSG00000136546), SCN2A (ENSG00000136531), SCN9A (ENSG00000169432), SCN3A (ENSG00000153253), SCN11A (ENSG000...
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Q59.267
Q59
What is the genetic target of the small molecule drug Lisdexamfetamine Dimesylate, and what is its status in clinical trials and FDA approval?
There are 3 genetic targets of the small molecule drug Lisdexamfetamine Dimesylate: SLC18A2, SLC6A2, and SLC6A3. Lisdexamfetamine Dimesylate reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%lisdexamfetamine dimesylate%" OR LOWER(tradeNames_string) LIKE "%lis...
[{'UUID': 'DrugGeneTargets_v2_2130', 'drugName': 'Lisdexamfetamine Dimesylate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC18A2 (ENSG00000165646), SLC6A2 (ENSG00000103546), SLC6A3 (ENSG00000142319)', 'yearOfFirstApproval': 2007, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'D...
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Q59.78
Q59
What is the genetic target of the protein drug Pasireotide Diaspartate, and what is its status in clinical trials and FDA approval?
There are 4 genetic targets of the protein drug Pasireotide Diaspartate: SSTR3, SSTR2, SSTR1, and SSTR5. Pasireotide Diaspartate reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%pasireotide diaspartate%" OR LOWER(tradeNames_string) LIKE "%pasireo...
[{'UUID': 'DrugGeneTargets_v2_1407', 'drugName': 'Pasireotide Diaspartate', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'SSTR3 (ENSG00000278195), SSTR2 (ENSG00000180616), SSTR1 (ENSG00000139874), SSTR5 (ENSG00000162009)', 'yearOfFirstApproval': 2012, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {...
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Q59.1785
Q59
What is the genetic target of the small molecule drug Barasertib, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Barasertib is AURKB. Barasertib reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%barasertib%" OR LOWER(tradeNames_string) LIKE "%barasertib%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_3821', 'drugName': 'Barasertib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'AURKB (ENSG00000178999)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}]
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Q59.450
Q59
What is the genetic target of the small molecule drug Mefenamic Acid, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Mefenamic Acid: PTGS2 and PTGS1. Mefenamic Acid reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%mefenamic acid%" OR LOWER(tradeNames_string) LIKE "%mefenamic acid%"...
[{'UUID': 'DrugGeneTargets_v2_4888', 'drugName': 'Mefenamic Acid', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGS2 (ENSG00000073756), PTGS1 (ENSG00000095303)', 'yearOfFirstApproval': 1967, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.401
Q59
What is the genetic target of the small molecule drug Cortivazol, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Cortivazol is NR3C1. Cortivazol reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%cortivazol%" OR LOWER(tradeNames_string) LIKE "%cortivazol%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_2892', 'drugName': 'Cortivazol', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'NR3C1 (ENSG00000113580)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.179
Q59
What is the genetic target of the small molecule drug Mephenytoin, and what is its status in clinical trials and FDA approval?
There are 10 genetic targets of the small molecule drug Mephenytoin: SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. Mephenytoin reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%mephenytoin%" OR LOWER(tradeNames_string) LIKE "%mephenytoin%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_5011', 'drugName': 'Mephenytoin', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SCN1A (ENSG00000144285), SCN5A (ENSG00000183873), SCN4A (ENSG00000007314), SCN7A (ENSG00000136546), SCN2A (ENSG00000136531), SCN9A (ENSG00000169432), SCN3A (ENSG00000153253), SCN11A (ENSG00...
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Q59.1051
Q59
What is the genetic target of the small molecule drug Prenylamine, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Prenylamine: SCN5A and CALM1. Prenylamine reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%prenylamine%" OR LOWER(tradeNames_string) LIKE "%prenylamine%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_5448', 'drugName': 'Prenylamine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SCN5A (ENSG00000183873), CALM1 (ENSG00000198668)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_5449', 'drugName': 'Prenylamin...
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Q59.1737
Q59
What is the genetic target of the small molecule drug Azd-1656, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Azd-1656 is GCK. Azd-1656 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%azd-1656%" OR LOWER(tradeNames_string) LIKE "%azd-1656%" OR LOWER(dr...
[{'UUID': 'DrugGeneTargets_v2_1410', 'drugName': 'Azd-1656', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'GCK (ENSG00000106633)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}]
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Q59.1609
Q59
What is the genetic target of the small molecule drug Proparacaine Hydrochloride, and what is its status in clinical trials and FDA approval?
There are 10 genetic targets of the small molecule drug Proparacaine Hydrochloride: SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. Proparacaine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%proparacaine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%prop...
[{'UUID': 'DrugGeneTargets_v2_2948', 'drugName': 'Proparacaine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SCN1A (ENSG00000144285), SCN5A (ENSG00000183873), SCN4A (ENSG00000007314), SCN7A (ENSG00000136546), SCN2A (ENSG00000136531), SCN9A (ENSG00000169432), SCN3A (ENSG00000153253),...
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Q59.1869
Q59
What is the genetic target of the protein drug Svn53-67/M57-Klh Peptide Vaccine, and what is its status in clinical trials and FDA approval?
The genetic target of the protein drug Svn53-67/M57-Klh Peptide Vaccine is BIRC5. Svn53-67/M57-Klh Peptide Vaccine reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%svn53-67/m57-klh peptide vaccine%" OR LOWER(tradeNames_string) LIKE ...
[{'UUID': 'DrugGeneTargets_v2_3713', 'drugName': 'Svn53-67/M57-Klh Peptide Vaccine', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'BIRC5 (ENSG00000089685)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_3714', 'drugName': 'Svn53-67/M57-Klh Pep...
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Q59.602
Q59
What is the genetic target of the small molecule drug Fedratinib Hydrochloride, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Fedratinib Hydrochloride: JAK2 and FLT3. Fedratinib Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%fedratinib hydrochloride%" OR LOWER(tradeNames_string) LIKE "%fedrat...
[{'UUID': 'DrugGeneTargets_v2_4654', 'drugName': 'Fedratinib Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'JAK2 (ENSG00000096968), FLT3 (ENSG00000122025)', 'yearOfFirstApproval': 2019, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4655', 'drugName...
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Q59.63
Q59
What is the genetic target of the small molecule drug Pelitrexol, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Pelitrexol is GART. Pelitrexol reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%pelitrexol%" OR LOWER(tradeNames_string) LIKE "%pelitrexol%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_2859', 'drugName': 'Pelitrexol', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'GART (ENSG00000159131)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}]
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Q59.1309
Q59
What is the genetic target of the small molecule drug Allopurinol, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Allopurinol is XDH. Allopurinol reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%allopurinol%" OR LOWER(tradeNames_string) LIKE "%allopurinol%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_5751', 'drugName': 'Allopurinol', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'XDH (ENSG00000158125)', 'yearOfFirstApproval': 1966, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3457', 'drugName': 'Allopurinol Sodium', 'drugMolecula...
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Q59.879
Q59
What is the genetic target of the small molecule drug Diphenhydramine Citrate, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Diphenhydramine Citrate is HRH1. Diphenhydramine Citrate reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%diphenhydramine citrate%" OR LOWER(tradeNames_string) LIKE "%diphenh...
[{'UUID': 'DrugGeneTargets_v2_613', 'drugName': 'Diphenhydramine Citrate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH1 (ENSG00000196639)', 'yearOfFirstApproval': 2005, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1491
Q59
What is the genetic target of the small molecule drug Phenytoin Sodium, and what is its status in clinical trials and FDA approval?
There are 10 genetic targets of the small molecule drug Phenytoin Sodium: SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. Phenytoin Sodium reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%phenytoin sodium%" OR LOWER(tradeNames_string) LIKE "%phenytoin sodi...
[{'UUID': 'DrugGeneTargets_v2_1082', 'drugName': 'Phenytoin Sodium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SCN1A (ENSG00000144285), SCN5A (ENSG00000183873), SCN4A (ENSG00000007314), SCN7A (ENSG00000136546), SCN2A (ENSG00000136531), SCN9A (ENSG00000169432), SCN3A (ENSG00000153253), SCN11A (E...
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Q59.1880
Q59
What is the genetic target of the small molecule drug Suxamethonium, and what is its status in clinical trials and FDA approval?
There are 5 genetic targets of the small molecule drug Suxamethonium: CHRNA1, CHRNG, CHRNB1, CHRND, and CHRNE. Suxamethonium reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%suxamethonium%" OR LOWER(tradeNames_string) LIKE "%suxamethonium%" O...
[{'UUID': 'DrugGeneTargets_v2_6206', 'drugName': 'Suxamethonium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRNA1 (ENSG00000138435), CHRNG (ENSG00000196811), CHRNB1 (ENSG00000170175), CHRND (ENSG00000135902), CHRNE (ENSG00000108556)', 'yearOfFirstApproval': 1952, 'maxClinicalTrialPhase': 4, 'd...
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Q59.282
Q59
What is the genetic target of the protein drug Semaglutide, and what is its status in clinical trials and FDA approval?
The genetic target of the protein drug Semaglutide is GLP1R. Semaglutide reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%semaglutide%" OR LOWER(tradeNames_string) LIKE "%semaglutide%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_6086', 'drugName': 'Semaglutide', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'GLP1R (ENSG00000112164)', 'yearOfFirstApproval': 2017, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.37
Q59
What is the genetic target of the small molecule drug Azd-8848, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Azd-8848 is TLR7. Azd-8848 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%azd-8848%" OR LOWER(tradeNames_string) LIKE "%azd-8848%" OR LOWER(dr...
[{'UUID': 'DrugGeneTargets_v2_3550', 'drugName': 'Azd-8848', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TLR7 (ENSG00000196664)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}]
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Q59.1517
Q59
What is the genetic target of the protein drug Gonadorelin Acetate, and what is its status in clinical trials and FDA approval?
The genetic target of the protein drug Gonadorelin Acetate is GNRHR. Gonadorelin Acetate reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%gonadorelin acetate%" OR LOWER(tradeNames_string) LIKE "%gonadorelin...
[{'UUID': 'DrugGeneTargets_v2_3355', 'drugName': 'Gonadorelin Acetate', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'GNRHR (ENSG00000109163)', 'yearOfFirstApproval': 1989, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.669
Q59
What is the genetic target of the small molecule drug Medroxyprogesterone Acetate, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Medroxyprogesterone Acetate is PGR. Medroxyprogesterone Acetate reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%medroxyprogesterone acetate%" OR LOWER(tradeNames_string) LIKE "%med...
[{'UUID': 'DrugGeneTargets_v2_2722', 'drugName': 'Medroxyprogesterone Acetate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PGR (ENSG00000082175)', 'yearOfFirstApproval': 1959, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1829
Q59
What is the genetic target of the small molecule drug Phenazopyridine Hydrochloride, and what is its status in clinical trials and FDA approval?
There are 10 genetic targets of the small molecule drug Phenazopyridine Hydrochloride: SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. Phenazopyridine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%phenazopyridine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%p...
[{'UUID': 'DrugGeneTargets_v2_1016', 'drugName': 'Phenazopyridine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SCN1A (ENSG00000144285), SCN5A (ENSG00000183873), SCN4A (ENSG00000007314), SCN7A (ENSG00000136546), SCN2A (ENSG00000136531), SCN9A (ENSG00000169432), SCN3A (ENSG0000015325...
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Q59.1446
Q59
What is the genetic target of the small molecule drug Indoprofen, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Indoprofen: PTGS2 and PTGS1. Indoprofen reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%indoprofen%" OR LOWER(tradeNames_string) LIKE "%indoprofen%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_4357', 'drugName': 'Indoprofen', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGS2 (ENSG00000073756), PTGS1 (ENSG00000095303)', 'yearOfFirstApproval': 1979, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.986
Q59
What is the genetic target of the small molecule drug Siponimod, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Siponimod is S1PR1. Siponimod reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%siponimod%" OR LOWER(tradeNames_string) LIKE "%siponimod%" OR LOWER(...
[{'UUID': 'DrugGeneTargets_v2_4451', 'drugName': 'Siponimod Fumarate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'S1PR1 (ENSG00000170989)', 'yearOfFirstApproval': 2019, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_265', 'drugName': 'Siponimod', 'drugMolecular...
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Q59.1572
Q59
What is the genetic target of the protein drug Brimapitide, C-Terminal Acid, and what is its status in clinical trials and FDA approval?
The genetic target of the protein drug Brimapitide, C-Terminal Acid is MAPK10. Brimapitide, C-Terminal Acid reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%brimapitide, c-terminal acid%" OR LOWER(tradeNames_string) LIKE "%br...
[{'UUID': 'DrugGeneTargets_v2_504', 'drugName': 'Brimapitide, C-Terminal Acid', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'MAPK10 (ENSG00000109339)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}]
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Q59.745
Q59
What is the genetic target of the oligonucleotide drug Nusinersen, and what is its status in clinical trials and FDA approval?
The genetic target of the oligonucleotide drug Nusinersen is SMN2. Nusinersen reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%nusinersen%" OR LOWER(tradeNames_string) LIKE "%nusinersen%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_2674', 'drugName': 'Nusinersen', 'drugMolecularType': 'Oligonucleotide', 'newLinkedTargets_string': 'SMN2 (ENSG00000205571)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_6328', 'drugName': 'Nusinersen Sodium', 'drugMolecularTy...
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Q59.194
Q59
What is the genetic target of the small molecule drug Dacomitinib, and what is its status in clinical trials and FDA approval?
There are 3 genetic targets of the small molecule drug Dacomitinib: ERBB4, ERBB2, and EGFR. Dacomitinib reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%dacomitinib%" OR LOWER(tradeNames_string) LIKE "%dacomitinib%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_3948', 'drugName': 'Dacomitinib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ERBB4 (ENSG00000178568), ERBB2 (ENSG00000141736), EGFR (ENSG00000146648)', 'yearOfFirstApproval': 2018, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_481...
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Q59.927
Q59
What is the genetic target of the small molecule drug Guanadrel, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Guanadrel is SLC6A2. Guanadrel reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%guanadrel%" OR LOWER(tradeNames_string) LIKE "%guanadrel%" OR LOWER(...
[{'UUID': 'DrugGeneTargets_v2_380', 'drugName': 'Guanadrel', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A2 (ENSG00000103546)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2355', 'drugName': 'Guanadrel Sulfate', 'drugMolecular...
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Q59.462
Q59
What is the genetic target of the small molecule drug Azelastine, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Azelastine is HRH1. Azelastine reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%azelastine%" OR LOWER(tradeNames_string) LIKE "%azelastine%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_3567', 'drugName': 'Azelastine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH1 (ENSG00000196639)', 'yearOfFirstApproval': 1996, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2721', 'drugName': 'Azelastine', 'drugMo...
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Q59.682
Q59
What is the genetic target of the small molecule drug Rauwolfia Serpentina, and what is its status in clinical trials and FDA approval?
There are 6 genetic targets of the small molecule drug Rauwolfia Serpentina: ADRA1A, ADRA2A, ADRA2C, ADRA1D, ADRA1B, and ADRA2B. Rauwolfia Serpentina reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%rauwolfia serpentina%" OR LOWER(tradeNames_string) LIKE "%rauwolfia ...
[{'UUID': 'DrugGeneTargets_v2_4856', 'drugName': 'Rauwolfia Serpentina', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRA1A (ENSG00000120907), ADRA2A (ENSG00000150594), ADRA2C (ENSG00000184160), ADRA1D (ENSG00000171873), ADRA1B (ENSG00000170214), ADRA2B (ENSG00000274286)', 'yearOfFirstApproval': ...
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Q59.767
Q59
What is the genetic target of the small molecule drug Arry-797, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Arry-797 is MAPK14. Arry-797 reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%arry-797%" OR LOWER(tradeNames_string) LIKE "%arry-797%" OR LOWER(dr...
[{'UUID': 'DrugGeneTargets_v2_319', 'drugName': 'Arry-797', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'MAPK14 (ENSG00000112062)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}]
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Q59.1809
Q59
What is the genetic target of the small molecule drug Dinoprostone, and what is its status in clinical trials and FDA approval?
There are 4 genetic targets of the small molecule drug Dinoprostone: PTGER1, PTGER4, PTGER2, and PTGER3. Dinoprostone reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%dinoprostone%" OR LOWER(tradeNames_string) LIKE "%dinoprostone%" OR ...
[{'UUID': 'DrugGeneTargets_v2_4965', 'drugName': 'Dinoprostone', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGER1 (ENSG00000160951), PTGER4 (ENSG00000171522), PTGER2 (ENSG00000125384), PTGER3 (ENSG00000050628)', 'yearOfFirstApproval': 1977, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1603
Q59
What is the genetic target of the antibody drug Camoteskimab, and what is its status in clinical trials and FDA approval?
The genetic target of the antibody drug Camoteskimab is IL18. Camoteskimab reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%camoteskimab%" OR LOWER(tradeNames_string) LIKE "%camoteskimab%" OR ...
[{'UUID': 'DrugGeneTargets_v2_6087', 'drugName': 'Camoteskimab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'IL18 (ENSG00000150782)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}]
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Q59.735
Q59
What is the genetic target of the small molecule drug Phenylephrine Hydrochloride, and what is its status in clinical trials and FDA approval?
There are 3 genetic targets of the small molecule drug Phenylephrine Hydrochloride: ADRA1A, ADRA1D, and ADRA1B. Phenylephrine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%phenylephrine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%phe...
[{'UUID': 'DrugGeneTargets_v2_3941', 'drugName': 'Phenylephrine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRA1A (ENSG00000120907), ADRA1D (ENSG00000171873), ADRA1B (ENSG00000170214)', 'yearOfFirstApproval': 1952, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.418
Q59
What is the genetic target of the small molecule drug Ponesimod, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Ponesimod is S1PR1. Ponesimod reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%ponesimod%" OR LOWER(tradeNames_string) LIKE "%ponesimod%" OR LOWER(...
[{'UUID': 'DrugGeneTargets_v2_3600', 'drugName': 'Ponesimod', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'S1PR1 (ENSG00000170989)', 'yearOfFirstApproval': 2021, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1107
Q59
What is the genetic target of the small molecule drug Proxibarbal, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Proxibarbal: AOC1 and MAOA. Proxibarbal reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%proxibarbal%" OR LOWER(tradeNames_string) LIKE "%proxibarbal%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_472', 'drugName': 'Proxibarbal', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'AOC1 (ENSG00000002726), MAOA (ENSG00000189221)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_473', 'drugName': 'Proxibarbal', ...
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Q59.832
Q59
What is the genetic target of the small molecule drug Rizatriptan, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Rizatriptan: HTR1D and HTR1B. Rizatriptan reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%rizatriptan%" OR LOWER(tradeNames_string) LIKE "%rizatriptan%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_1141', 'drugName': 'Rizatriptan Benzoate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR1D (ENSG00000179546), HTR1B (ENSG00000135312)', 'yearOfFirstApproval': 1998, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1140', 'drugName':...
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Q59.1498
Q59
What is the genetic target of the small molecule drug Triciribine Phosphate, and what is its status in clinical trials and FDA approval?
There are 3 genetic targets of the small molecule drug Triciribine Phosphate: AKT2, AKT3, and AKT1. Triciribine Phosphate reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%triciribine phosphate%" OR LOWER(tradeNames_string) LIKE "%triciribi...
[{'UUID': 'DrugGeneTargets_v2_511', 'drugName': 'Triciribine Phosphate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'AKT2 (ENSG00000105221), AKT3 (ENSG00000117020), AKT1 (ENSG00000142208)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}]
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Q59.623
Q59
What is the genetic target of the small molecule drug Oxtriphylline, and what is its status in clinical trials and FDA approval?
There are 10 genetic targets of the small molecule drug Oxtriphylline: PDE3A, PDE3B, PDE4A, PDE4D, PDE4B, PDE4C, ADORA1, ADORA2B, ADORA3, and ADORA2A. Oxtriphylline reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%oxtriphylline%" OR LOWER(tradeNames_string) LIKE "%oxtriphylline%" O...
[{'UUID': 'DrugGeneTargets_v2_3797', 'drugName': 'Oxtriphylline', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PDE3A (ENSG00000172572), PDE3B (ENSG00000152270), PDE4A (ENSG00000065989), PDE4D (ENSG00000113448), PDE4B (ENSG00000184588), PDE4C (ENSG00000105650), ADORA1 (ENSG00000163485), ADORA2B (EN...
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