uuid stringlengths 4 8 | template_uuid stringclasses 40
values | question stringlengths 13 193 | answer stringlengths 29 2.2k | benchmark_query stringlengths 133 622 | execution_results stringlengths 2 1.14M | query_type stringclasses 2
values | sql_category stringclasses 26
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Q59.117 | Q59 | What is the genetic target of the small molecule drug Olodaterol, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Olodaterol is ADRB2. Olodaterol reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%olodaterol%" OR LOWER(tradeNames_string) LIKE "%olodaterol%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_5322', 'drugName': 'Olodaterol Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRB2 (ENSG00000169252)', 'yearOfFirstApproval': 2014, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4859', 'drugName': 'Olodaterol', 'drugM... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.423 | Q59 | What is the genetic target of the small molecule drug Chlorpheniramine Maleate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Chlorpheniramine Maleate is HRH1. Chlorpheniramine Maleate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%chlorpheniramine maleate%" OR LOWER(tradeNames_string) LIKE "%chlorp... | [{'UUID': 'DrugGeneTargets_v2_221', 'drugName': 'Chlorpheniramine Maleate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH1 (ENSG00000196639)', 'yearOfFirstApproval': 1950, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_6213', 'drugName': 'Dexchlorpheniramine M... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1911 | Q59 | What is the genetic target of the protein drug Catridecacog, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Catridecacog is F13A1. Catridecacog reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%catridecacog%" OR LOWER(tradeNames_string) LIKE "%catridecacog%" OR ... | [{'UUID': 'DrugGeneTargets_v2_886', 'drugName': 'Catridecacog', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'F13A1 (ENSG00000124491)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.978 | Q59 | What is the genetic target of the antibody drug Sirukumab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Sirukumab is IL6. Sirukumab reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%sirukumab%" OR LOWER(tradeNames_string) LIKE "%sirukumab%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_4491', 'drugName': 'Sirukumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'IL6 (ENSG00000136244)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.611 | Q59 | What is the genetic target of the small molecule drug Pralsetinib, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Pralsetinib: RET, CCDC6, and KIF5B. Pralsetinib reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%pralsetinib%" OR LOWER(tradeNames_string) LIKE "%pralsetinib%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_2687', 'drugName': 'Pralsetinib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'RET (ENSG00000165731), CCDC6 (ENSG00000108091), KIF5B (ENSG00000170759)', 'yearOfFirstApproval': 2020, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2688... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1919 | Q59 | What is the genetic target of the small molecule drug Fenoterol, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Fenoterol is ADRB2. Fenoterol reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%fenoterol%" OR LOWER(tradeNames_string) LIKE "%fenoterol%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_2226', 'drugName': 'Fenoterol', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRB2 (ENSG00000169252)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.92 | Q59 | What is the genetic target of the small molecule drug Lonaprisan, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Lonaprisan is PGR. Lonaprisan reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%lonaprisan%" OR LOWER(tradeNames_string) LIKE "%lonaprisan%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_2999', 'drugName': 'Lonaprisan', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PGR (ENSG00000082175)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.855 | Q59 | What is the genetic target of the small molecule drug Warfarin Sodium, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Warfarin Sodium is VKORC1. Warfarin Sodium reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%warfarin sodium%" OR LOWER(tradeNames_string) LIKE "%warfarin sodium... | [{'UUID': 'DrugGeneTargets_v2_38', 'drugName': 'Warfarin Sodium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'VKORC1 (ENSG00000167397)', 'yearOfFirstApproval': 1954, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1521 | Q59 | What is the genetic target of the small molecule drug Mifepristone, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Mifepristone: NR3C1 and PGR. Mifepristone reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%mifepristone%" OR LOWER(tradeNames_string) LIKE "%mifepristone%" OR ... | [{'UUID': 'DrugGeneTargets_v2_2929', 'drugName': 'Mifepristone', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'NR3C1 (ENSG00000113580), PGR (ENSG00000082175)', 'yearOfFirstApproval': 2000, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2930', 'drugName': 'Mifepris... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1918 | Q59 | What is the genetic target of the small molecule drug Oxybutynin Chloride, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Oxybutynin Chloride: CHRM3 and CHRM2. Oxybutynin Chloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%oxybutynin chloride%" OR LOWER(tradeNames_string) LIKE "%oxybutynin ... | [{'UUID': 'DrugGeneTargets_v2_871', 'drugName': 'Oxybutynin Chloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRM3 (ENSG00000133019), CHRM2 (ENSG00000181072)', 'yearOfFirstApproval': 1975, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_872', 'drugName': 'O... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.760 | Q59 | What is the genetic target of the small molecule drug Benoxinate, and what is its status in clinical trials and FDA approval? | There are 10 genetic targets of the small molecule drug Benoxinate: SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. Benoxinate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%benoxinate%" OR LOWER(tradeNames_string) LIKE "%benoxinate%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_1754', 'drugName': 'Benoxinate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SCN1A (ENSG00000144285), SCN5A (ENSG00000183873), SCN4A (ENSG00000007314), SCN7A (ENSG00000136546), SCN2A (ENSG00000136531), SCN9A (ENSG00000169432), SCN3A (ENSG00000153253), SCN11A (ENSG000... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.504 | Q59 | What is the genetic target of the protein drug Insulin Zinc Susp Recombinant Human, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Insulin Zinc Susp Recombinant Human is INSR. Insulin Zinc Susp Recombinant Human reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%insulin zinc susp recombinant human%" OR LOWER(tradeNames_string) LI... | [{'UUID': 'DrugGeneTargets_v2_5348', 'drugName': 'Insulin Zinc Susp Recombinant Human', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'INSR (ENSG00000171105)', 'yearOfFirstApproval': 1985, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1287 | Q59 | What is the genetic target of the small molecule drug Bretylium Tosylate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Bretylium Tosylate is SLC6A2. Bretylium Tosylate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%bretylium tosylate%" OR LOWER(tradeNames_string) LIKE "%bretylium to... | [{'UUID': 'DrugGeneTargets_v2_904', 'drugName': 'Bretylium Tosylate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A2 (ENSG00000103546)', 'yearOfFirstApproval': 1986, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1340 | Q59 | What is the genetic target of the small molecule drug Guanethidine, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Guanethidine is SLC6A2. Guanethidine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%guanethidine%" OR LOWER(tradeNames_string) LIKE "%guanethidine%" OR ... | [{'UUID': 'DrugGeneTargets_v2_4086', 'drugName': 'Guanethidine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A2 (ENSG00000103546)', 'yearOfFirstApproval': 1960, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2340', 'drugName': 'Guanethidine Monosulfate', 'dr... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.12 | Q59 | What is the genetic target of the small molecule drug Reproterol, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Reproterol is ADRB2. Reproterol reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%reproterol%" OR LOWER(tradeNames_string) LIKE "%reproterol%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_487', 'drugName': 'Reproterol', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRB2 (ENSG00000169252)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.402 | Q59 | What is the genetic target of the small molecule drug Eslicarbazepine, and what is its status in clinical trials and FDA approval? | There are 10 genetic targets of the small molecule drug Eslicarbazepine: SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. Eslicarbazepine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%eslicarbazepine%" OR LOWER(tradeNames_string) LIKE "%eslicarbazepine... | [{'UUID': 'DrugGeneTargets_v2_4666', 'drugName': 'Eslicarbazepine Acetate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SCN1A (ENSG00000144285), SCN5A (ENSG00000183873), SCN4A (ENSG00000007314), SCN7A (ENSG00000136546), SCN2A (ENSG00000136531), SCN9A (ENSG00000169432), SCN3A (ENSG00000153253), SC... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.288 | Q59 | What is the genetic target of the small molecule drug Reparixin, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Reparixin: CXCR1 and CXCR2. Reparixin reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%reparixin%" OR LOWER(tradeNames_string) LIKE "%reparixin%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_2753', 'drugName': 'Reparixin', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CXCR1 (ENSG00000163464), CXCR2 (ENSG00000180871)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_2754', 'drugName': 'Reparixin',... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1075 | Q59 | What is the genetic target of the small molecule drug Dextromethorphan, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Dextromethorphan: GRIN2A and SIGMAR1. Dextromethorphan reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%dextromethorphan%" OR LOWER(tradeNames_string) LIKE "%dextromethorph... | [{'UUID': 'DrugGeneTargets_v2_3605', 'drugName': 'Dextromethorphan Polistirex', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'GRIN2A (ENSG00000183454), SIGMAR1 (ENSG00000147955)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_5073', '... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1201 | Q59 | What is the genetic target of the small molecule drug Olanzapine Pamoate, and what is its status in clinical trials and FDA approval? | There are 5 genetic targets of the small molecule drug Olanzapine Pamoate: HTR2C, HTR2A, DRD2, DRD3, and DRD4. Olanzapine Pamoate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%olanzapine pamoate%" OR LOWER(tradeNames_string) LIKE "%olanzapine p... | [{'UUID': 'DrugGeneTargets_v2_1529', 'drugName': 'Olanzapine Pamoate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR2C (ENSG00000147246), HTR2A (ENSG00000102468), DRD2 (ENSG00000149295), DRD3 (ENSG00000151577), DRD4 (ENSG00000069696)', 'yearOfFirstApproval': 2009, 'maxClinicalTrialPhase': 4, 'd... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1746 | Q59 | What is the genetic target of the small molecule drug Tegoprazan, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Tegoprazan: ATP4A and ATP4B. Tegoprazan reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tegoprazan%" OR LOWER(tradeNames_string) LIKE "%tegoprazan%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_1354', 'drugName': 'Tegoprazan', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ATP4A (ENSG00000105675), ATP4B (ENSG00000186009)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.697 | Q59 | What is the genetic target of the small molecule drug Methylpromazine, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Methylpromazine is HRH1. Methylpromazine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%methylpromazine%" OR LOWER(tradeNames_string) LIKE "%methylpromazine... | [{'UUID': 'DrugGeneTargets_v2_2846', 'drugName': 'Methylpromazine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH1 (ENSG00000196639)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3705', 'drugName': 'Trimeprazine Tartrate', 'drug... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1632 | Q59 | What is the genetic target of the small molecule drug Flunisolide, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Flunisolide is NR3C1. Flunisolide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%flunisolide%" OR LOWER(tradeNames_string) LIKE "%flunisolide%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_5320', 'drugName': 'Flunisolide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'NR3C1 (ENSG00000113580)', 'yearOfFirstApproval': 1981, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1877 | Q59 | What is the genetic target of the small molecule drug Indecainide Hydrochloride, and what is its status in clinical trials and FDA approval? | There are 10 genetic targets of the small molecule drug Indecainide Hydrochloride: SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. Indecainide Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%indecainide hydrochloride%" OR LOWER(tradeNames_string) LIKE "%indec... | [{'UUID': 'DrugGeneTargets_v2_6337', 'drugName': 'Indecainide Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SCN1A (ENSG00000144285), SCN5A (ENSG00000183873), SCN4A (ENSG00000007314), SCN7A (ENSG00000136546), SCN2A (ENSG00000136531), SCN9A (ENSG00000169432), SCN3A (ENSG00000153253), ... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.696 | Q59 | What is the genetic target of the antibody drug Odronextamab, and what is its status in clinical trials and FDA approval? | There are 4 genetic targets of the antibody drug Odronextamab: CD3E, CD3G, CD3D, and MS4A1. Odronextamab reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%odronextamab%" OR LOWER(tradeNames_string) LIKE "%odronextamab%" OR ... | [{'UUID': 'DrugGeneTargets_v2_1602', 'drugName': 'Odronextamab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'CD3E (ENSG00000198851), CD3G (ENSG00000160654), CD3D (ENSG00000167286), MS4A1 (ENSG00000156738)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}, {'UUID': 'DrugGe... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.858 | Q59 | What is the genetic target of the small molecule drug Everolimus, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Everolimus is FKBP1A. Everolimus reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%everolimus%" OR LOWER(tradeNames_string) LIKE "%everolimus%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_1925', 'drugName': 'Everolimus', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'FKBP1A (ENSG00000088832)', 'yearOfFirstApproval': 2009, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.162 | Q59 | What is the genetic target of the small molecule drug Avatrombopag, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Avatrombopag is MPL. Avatrombopag reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%avatrombopag%" OR LOWER(tradeNames_string) LIKE "%avatrombopag%" OR ... | [{'UUID': 'DrugGeneTargets_v2_6055', 'drugName': 'Avatrombopag', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'MPL (ENSG00000117400)', 'yearOfFirstApproval': 2018, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_6317', 'drugName': 'Avatrombopag Maleate', 'drugMolec... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.902 | Q59 | What is the genetic target of the small molecule drug Dofetilide, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Dofetilide is KCNH2. Dofetilide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%dofetilide%" OR LOWER(tradeNames_string) LIKE "%dofetilide%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_1039', 'drugName': 'Dofetilide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'KCNH2 (ENSG00000055118)', 'yearOfFirstApproval': 1999, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1576 | Q59 | What is the genetic target of the small molecule drug Olsalazine Sodium, and what is its status in clinical trials and FDA approval? | There are 4 genetic targets of the small molecule drug Olsalazine Sodium: PPARG, PTGS2, PTGS1, and ALOX5. Olsalazine Sodium reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%olsalazine sodium%" OR LOWER(tradeNames_string) LIKE "%olsalazine so... | [{'UUID': 'DrugGeneTargets_v2_3913', 'drugName': 'Olsalazine Sodium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PPARG (ENSG00000132170), PTGS2 (ENSG00000073756), PTGS1 (ENSG00000095303), ALOX5 (ENSG00000012779)', 'yearOfFirstApproval': 1990, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, ... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.260 | Q59 | What is the genetic target of the small molecule drug Doxapram, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Doxapram: KCNK3 and KCNK9. Doxapram reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%doxapram%" OR LOWER(tradeNames_string) LIKE "%doxapram%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_6167', 'drugName': 'Doxapram Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'KCNK3 (ENSG00000171303), KCNK9 (ENSG00000169427)', 'yearOfFirstApproval': 1965, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_6166', 'drugName... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.339 | Q59 | What is the genetic target of the antibody drug Guselkumab, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the antibody drug Guselkumab: IL12B and IL23A. Guselkumab reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%guselkumab%" OR LOWER(tradeNames_string) LIKE "%guselkumab%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_2147', 'drugName': 'Guselkumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'IL12B (ENSG00000113302), IL23A (ENSG00000110944)', 'yearOfFirstApproval': 2017, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1881 | Q59 | What is the genetic target of the small molecule drug Idelalisib, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Idelalisib is PIK3CD. Idelalisib reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%idelalisib%" OR LOWER(tradeNames_string) LIKE "%idelalisib%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_3742', 'drugName': 'Idelalisib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PIK3CD (ENSG00000171608)', 'yearOfFirstApproval': 2014, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1048 | Q59 | What is the genetic target of the small molecule drug Bromocriptine, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Bromocriptine: DRD2, DRD3, and DRD4. Bromocriptine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%bromocriptine%" OR LOWER(tradeNames_string) LIKE "%bromocriptine%" O... | [{'UUID': 'DrugGeneTargets_v2_630', 'drugName': 'Bromocriptine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DRD2 (ENSG00000149295), DRD3 (ENSG00000151577), DRD4 (ENSG00000069696)', 'yearOfFirstApproval': 1978, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4746... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.521 | Q59 | What is the genetic target of the small molecule drug Nebentan, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Nebentan is EDNRA. Nebentan reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%nebentan%" OR LOWER(tradeNames_string) LIKE "%nebentan%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_3949', 'drugName': 'Nebentan', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'EDNRA (ENSG00000151617)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1363 | Q59 | What is the genetic target of the small molecule drug Testosterone Enanthate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Testosterone Enanthate is AR. Testosterone Enanthate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%testosterone enanthate%" OR LOWER(tradeNames_string) LIKE "%testoste... | [{'UUID': 'DrugGeneTargets_v2_5959', 'drugName': 'Testosterone Enanthate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'AR (ENSG00000169083)', 'yearOfFirstApproval': 1953, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1024 | Q59 | What is the genetic target of the small molecule drug Lofexidine, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Lofexidine: ADRA2A, ADRA2C, and ADRA2B. Lofexidine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%lofexidine%" OR LOWER(tradeNames_string) LIKE "%lofexidine%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_3839', 'drugName': 'Lofexidine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRA2A (ENSG00000150594), ADRA2C (ENSG00000184160), ADRA2B (ENSG00000274286)', 'yearOfFirstApproval': 2018, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.775 | Q59 | What is the genetic target of the small molecule drug Umeclidinium Bromide, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Umeclidinium Bromide is CHRM3. Umeclidinium Bromide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%umeclidinium bromide%" OR LOWER(tradeNames_string) LIKE "%umeclidini... | [{'UUID': 'DrugGeneTargets_v2_5459', 'drugName': 'Umeclidinium Bromide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRM3 (ENSG00000133019)', 'yearOfFirstApproval': 2013, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1748 | Q59 | What is the genetic target of the small molecule drug Elismetrep, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Elismetrep is TRPM8. Elismetrep reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%elismetrep%" OR LOWER(tradeNames_string) LIKE "%elismetrep%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_858', 'drugName': 'Elismetrep', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TRPM8 (ENSG00000144481)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.768 | Q59 | What is the genetic target of the protein drug Eptifibatide, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the protein drug Eptifibatide: ITGB3 and ITGA2B. Eptifibatide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%eptifibatide%" OR LOWER(tradeNames_string) LIKE "%eptifibatide%" OR ... | [{'UUID': 'DrugGeneTargets_v2_1804', 'drugName': 'Eptifibatide', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'ITGB3 (ENSG00000259207), ITGA2B (ENSG00000005961)', 'yearOfFirstApproval': 1998, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1256 | Q59 | What is the genetic target of the protein drug Atacicept, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the protein drug Atacicept: TNFSF13B and TNFSF13. Atacicept reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%atacicept%" OR LOWER(tradeNames_string) LIKE "%atacicept%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_4638', 'drugName': 'Atacicept', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'TNFSF13B (ENSG00000102524), TNFSF13 (ENSG00000161955)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_4639', 'drugName': 'Atacicept', '... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1213 | Q59 | What is the genetic target of the small molecule drug Fenfluramine Hydrochloride, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Fenfluramine Hydrochloride: HTR2C, HTR1D, and SIGMAR1. Fenfluramine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%fenfluramine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%fenf... | [{'UUID': 'DrugGeneTargets_v2_3887', 'drugName': 'Fenfluramine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR2C (ENSG00000147246), HTR1D (ENSG00000179546), SIGMAR1 (ENSG00000147955)', 'yearOfFirstApproval': 2020, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'Drug... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1469 | Q59 | What is the genetic target of the small molecule drug Butamben Picrate, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Butamben Picrate: TRPV4 and TRPA1. Butamben Picrate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%butamben picrate%" OR LOWER(tradeNames_string) LIKE "%butamben picra... | [{'UUID': 'DrugGeneTargets_v2_268', 'drugName': 'Butamben Picrate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TRPV4 (ENSG00000111199), TRPA1 (ENSG00000104321)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_269', 'drugName': 'Butambe... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1984 | Q59 | What is the genetic target of the small molecule drug Naloxone Hydrochloride, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Naloxone Hydrochloride: OPRK1, OPRD1, and OPRM1. Naloxone Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%naloxone hydrochloride%" OR LOWER(tradeNames_string) LIKE "%naloxone... | [{'UUID': 'DrugGeneTargets_v2_3927', 'drugName': 'Naloxone Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'OPRK1 (ENSG00000082556), OPRD1 (ENSG00000116329), OPRM1 (ENSG00000112038)', 'yearOfFirstApproval': 1971, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.527 | Q59 | What is the genetic target of the small molecule drug Niraparib, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Niraparib: PARP2 and PARP1. Niraparib reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%niraparib%" OR LOWER(tradeNames_string) LIKE "%niraparib%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_4883', 'drugName': 'Niraparib Tosylate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PARP2 (ENSG00000129484), PARP1 (ENSG00000143799)', 'yearOfFirstApproval': 2017, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4882', 'drugName': '... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.23 | Q59 | What is the genetic target of the enzyme drug Alfimeprase, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the enzyme drug Alfimeprase: FGA, FGB, and FGG. Alfimeprase reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%alfimeprase%" OR LOWER(tradeNames_string) LIKE "%alfimeprase%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_3582', 'drugName': 'Alfimeprase', 'drugMolecularType': 'Enzyme', 'newLinkedTargets_string': 'FGA (ENSG00000171560), FGB (ENSG00000171564), FGG (ENSG00000171557)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.361 | Q59 | What is the genetic target of the small molecule drug Maraviroc, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Maraviroc is CCR5. Maraviroc reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%maraviroc%" OR LOWER(tradeNames_string) LIKE "%maraviroc%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_3537', 'drugName': 'Maraviroc', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CCR5 (ENSG00000160791)', 'yearOfFirstApproval': 2007, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1288 | Q59 | What is the genetic target of the small molecule drug Somapacitan, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Somapacitan is GHR. Somapacitan reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%somapacitan%" OR LOWER(tradeNames_string) LIKE "%somapacitan%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_3588', 'drugName': 'Somapacitan', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'GHR (ENSG00000112964)', 'yearOfFirstApproval': 2020, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1326 | Q59 | What is the genetic target of the small molecule drug Perhexiline Maleate, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Perhexiline Maleate: MTOR, CPT2, and CPT1B. Perhexiline Maleate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%perhexiline maleate%" OR LOWER(tradeNames_string) LIKE "%perhexiline... | [{'UUID': 'DrugGeneTargets_v2_1724', 'drugName': 'Perhexiline Maleate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'MTOR (ENSG00000198793), CPT2 (ENSG00000157184), CPT1B (ENSG00000205560)', 'yearOfFirstApproval': 1974, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1683 | Q59 | What is the genetic target of the small molecule drug Procaine, and what is its status in clinical trials and FDA approval? | There are 10 genetic targets of the small molecule drug Procaine: SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. Procaine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%procaine%" OR LOWER(tradeNames_string) LIKE "%procaine%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_1754', 'drugName': 'Benoxinate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SCN1A (ENSG00000144285), SCN5A (ENSG00000183873), SCN4A (ENSG00000007314), SCN7A (ENSG00000136546), SCN2A (ENSG00000136531), SCN9A (ENSG00000169432), SCN3A (ENSG00000153253), SCN11A (ENSG000... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.344 | Q59 | What is the genetic target of the small molecule drug Mizolastine, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Mizolastine is HRH1. Mizolastine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%mizolastine%" OR LOWER(tradeNames_string) LIKE "%mizolastine%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_1653', 'drugName': 'Mizolastine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH1 (ENSG00000196639)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.437 | Q59 | What is the genetic target of the antibody drug Teprotumumab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Teprotumumab is IGF1R. Teprotumumab reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%teprotumumab%" OR LOWER(tradeNames_string) LIKE "%teprotumumab%" OR ... | [{'UUID': 'DrugGeneTargets_v2_1336', 'drugName': 'Teprotumumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'IGF1R (ENSG00000140443)', 'yearOfFirstApproval': 2020, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.479 | Q59 | What is the genetic target of the small molecule drug Antrafenine, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Antrafenine is PTGDS. Antrafenine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%antrafenine%" OR LOWER(tradeNames_string) LIKE "%antrafenine%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_3195', 'drugName': 'Antrafenine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGDS (ENSG00000107317)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.220 | Q59 | What is the genetic target of the small molecule drug Tripelennamine Citrate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Tripelennamine Citrate is HRH1. Tripelennamine Citrate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tripelennamine citrate%" OR LOWER(tradeNames_string) LIKE "%tripelen... | [{'UUID': 'DrugGeneTargets_v2_703', 'drugName': 'Tripelennamine Citrate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH1 (ENSG00000196639)', 'yearOfFirstApproval': 1948, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.919 | Q59 | What is the genetic target of the small molecule drug Mt-3995, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Mt-3995 is NR3C2. Mt-3995 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%mt-3995%" OR LOWER(tradeNames_string) LIKE "%mt-3995%" OR LOWER(drug... | [{'UUID': 'DrugGeneTargets_v2_2360', 'drugName': 'Mt-3995', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'NR3C2 (ENSG00000151623)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1237 | Q59 | What is the genetic target of the small molecule drug Oxandrolone, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Oxandrolone is AR. Oxandrolone reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%oxandrolone%" OR LOWER(tradeNames_string) LIKE "%oxandrolone%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_3386', 'drugName': 'Oxandrolone', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'AR (ENSG00000169083)', 'yearOfFirstApproval': 1964, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2216', 'drugName': 'Methyltestosterone', 'drugMolecular... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1597 | Q59 | What is the genetic target of the protein drug Nonacog Beta Pegol, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Nonacog Beta Pegol is F9. Nonacog Beta Pegol reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%nonacog beta pegol%" OR LOWER(tradeNames_string) LIKE "%nonacog beta... | [{'UUID': 'DrugGeneTargets_v2_1851', 'drugName': 'Nonacog Beta Pegol', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'F9 (ENSG00000101981)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1020 | Q59 | What is the genetic target of the small molecule drug Tafluprost, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Tafluprost is PTGFR. Tafluprost reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tafluprost%" OR LOWER(tradeNames_string) LIKE "%tafluprost%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_4212', 'drugName': 'Tafluprost', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGFR (ENSG00000122420)', 'yearOfFirstApproval': 2012, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1950 | Q59 | What is the genetic target of the small molecule drug Atopaxar, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Atopaxar is F2R. Atopaxar reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%atopaxar%" OR LOWER(tradeNames_string) LIKE "%atopaxar%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_6380', 'drugName': 'Atopaxar', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'F2R (ENSG00000181104)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.96 | Q59 | What is the genetic target of the antibody drug Elezanumab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Elezanumab is RGMA. Elezanumab reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%elezanumab%" OR LOWER(tradeNames_string) LIKE "%elezanumab%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_4257', 'drugName': 'Elezanumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'RGMA (ENSG00000182175)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1017 | Q59 | What is the genetic target of the small molecule drug Bromocriptine Mesylate, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Bromocriptine Mesylate: DRD2, DRD3, and DRD4. Bromocriptine Mesylate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%bromocriptine mesylate%" OR LOWER(tradeNames_string) LIKE "%bromocri... | [{'UUID': 'DrugGeneTargets_v2_4746', 'drugName': 'Bromocriptine Mesylate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DRD2 (ENSG00000149295), DRD3 (ENSG00000151577), DRD4 (ENSG00000069696)', 'yearOfFirstApproval': 1978, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1079 | Q59 | What is the genetic target of the small molecule drug Hydrocortisone Butyrate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Hydrocortisone Butyrate is NR3C1. Hydrocortisone Butyrate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%hydrocortisone butyrate%" OR LOWER(tradeNames_string) LIKE "%hydroco... | [{'UUID': 'DrugGeneTargets_v2_3811', 'drugName': 'Hydrocortisone Butyrate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'NR3C1 (ENSG00000113580)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2728', 'drugName': 'Hydrocortisone Probu... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1101 | Q59 | What is the genetic target of the antibody drug Evinacumab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Evinacumab is ANGPTL3. Evinacumab reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%evinacumab%" OR LOWER(tradeNames_string) LIKE "%evinacumab%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_5281', 'drugName': 'Evinacumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'ANGPTL3 (ENSG00000132855)', 'yearOfFirstApproval': 2021, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1586 | Q59 | What is the genetic target of the small molecule drug Danazol, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Danazol: AR and PGR. Danazol reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%danazol%" OR LOWER(tradeNames_string) LIKE "%danazol%" OR LOWER(drug... | [{'UUID': 'DrugGeneTargets_v2_4916', 'drugName': 'Danazol', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'AR (ENSG00000169083), PGR (ENSG00000082175)', 'yearOfFirstApproval': 1976, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4917', 'drugName': 'Danazol', 'drugM... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1321 | Q59 | What is the genetic target of the small molecule drug Nefazodone Hydrochloride, and what is its status in clinical trials and FDA approval? | There are 4 genetic targets of the small molecule drug Nefazodone Hydrochloride: HTR2A, HTR2C, SLC6A4, and SLC6A2. Nefazodone Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%nefazodone hydrochloride%" OR LOWER(tradeNames_string) LIKE "%nefazo... | [{'UUID': 'DrugGeneTargets_v2_5046', 'drugName': 'Nefazodone Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR2A (ENSG00000102468), HTR2C (ENSG00000147246), SLC6A4 (ENSG00000108576), SLC6A2 (ENSG00000103546)', 'yearOfFirstApproval': 1994, 'maxClinicalTrialPhase': 4, 'drugIsApproved'... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.703 | Q59 | What is the genetic target of the small molecule drug Mesoridazine, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Mesoridazine: HTR2A and DRD2. Mesoridazine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%mesoridazine%" OR LOWER(tradeNames_string) LIKE "%mesoridazine%" OR ... | [{'UUID': 'DrugGeneTargets_v2_4488', 'drugName': 'Mesoridazine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR2A (ENSG00000102468), DRD2 (ENSG00000149295)', 'yearOfFirstApproval': 1970, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4487', 'drugName': 'Mesorid... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1794 | Q59 | What is the genetic target of the small molecule drug Buspirone, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Buspirone is HTR1A. Buspirone reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%buspirone%" OR LOWER(tradeNames_string) LIKE "%buspirone%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_4302', 'drugName': 'Buspirone Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR1A (ENSG00000178394)', 'yearOfFirstApproval': 1986, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_541', 'drugName': 'Buspirone', 'drugMole... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1005 | Q59 | What is the genetic target of the small molecule drug Clonidine Hydrochloride, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Clonidine Hydrochloride: ADRA2A, ADRA2C, and ADRA2B. Clonidine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%clonidine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%clonidi... | [{'UUID': 'DrugGeneTargets_v2_4092', 'drugName': 'Clonidine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRA2A (ENSG00000150594), ADRA2C (ENSG00000184160), ADRA2B (ENSG00000274286)', 'yearOfFirstApproval': 1974, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGe... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.156 | Q59 | What is the genetic target of the oligonucleotide drug Givosiran Sodium, and what is its status in clinical trials and FDA approval? | The genetic target of the oligonucleotide drug Givosiran Sodium is ALAS1. Givosiran Sodium reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%givosiran sodium%" OR LOWER(tradeNames_string) LIKE "%givosiran sodi... | [{'UUID': 'DrugGeneTargets_v2_5803', 'drugName': 'Givosiran Sodium', 'drugMolecularType': 'Oligonucleotide', 'newLinkedTargets_string': 'ALAS1 (ENSG00000023330)', 'yearOfFirstApproval': 2019, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1108 | Q59 | What is the genetic target of the protein drug Epoetin Zeta, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Epoetin Zeta is EPOR. Epoetin Zeta reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%epoetin zeta%" OR LOWER(tradeNames_string) LIKE "%epoetin zeta%" OR ... | [{'UUID': 'DrugGeneTargets_v2_4677', 'drugName': 'Epoetin Zeta', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'EPOR (ENSG00000187266)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1719 | Q59 | What is the genetic target of the small molecule drug Sulfasalazine, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Sulfasalazine: ALOX5, PTGS2, and PTGS1. Sulfasalazine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%sulfasalazine%" OR LOWER(tradeNames_string) LIKE "%sulfasalazine%" O... | [{'UUID': 'DrugGeneTargets_v2_3015', 'drugName': 'Sulfasalazine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ALOX5 (ENSG00000012779), PTGS2 (ENSG00000073756), PTGS1 (ENSG00000095303)', 'yearOfFirstApproval': 1950, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1998 | Q59 | What is the genetic target of the small molecule drug Pacritinib Citrate, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Pacritinib Citrate: JAK2 and FLT3. Pacritinib Citrate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%pacritinib citrate%" OR LOWER(tradeNames_string) LIKE "%pacritinib c... | [{'UUID': 'DrugGeneTargets_v2_1106', 'drugName': 'Pacritinib Citrate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'JAK2 (ENSG00000096968), FLT3 (ENSG00000122025)', 'yearOfFirstApproval': 2022, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1107', 'drugName': 'Pa... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.796 | Q59 | What is the genetic target of the small molecule drug Venlafaxine Hydrochloride, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Venlafaxine Hydrochloride: SLC6A4 and SLC6A2. Venlafaxine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%venlafaxine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%venla... | [{'UUID': 'DrugGeneTargets_v2_1502', 'drugName': 'Venlafaxine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A4 (ENSG00000108576), SLC6A2 (ENSG00000103546)', 'yearOfFirstApproval': 1993, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1503', 'dru... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.587 | Q59 | What is the genetic target of the small molecule drug Dexketoprofen, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Dexketoprofen: PTGS2 and PTGS1. Dexketoprofen reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%dexketoprofen%" OR LOWER(tradeNames_string) LIKE "%dexketoprofen%" O... | [{'UUID': 'DrugGeneTargets_v2_5314', 'drugName': 'Dexketoprofen', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGS2 (ENSG00000073756), PTGS1 (ENSG00000095303)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.710 | Q59 | What is the genetic target of the small molecule drug Ranolazine, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Ranolazine: SCN4A and SCN5A. Ranolazine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ranolazine%" OR LOWER(tradeNames_string) LIKE "%ranolazine%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_6340', 'drugName': 'Ranolazine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SCN4A (ENSG00000007314), SCN5A (ENSG00000183873)', 'yearOfFirstApproval': 2006, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_6341', 'drugName': 'Ranolazi... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1222 | Q59 | What is the genetic target of the small molecule drug Icenticaftor, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Icenticaftor is CFTR. Icenticaftor reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%icenticaftor%" OR LOWER(tradeNames_string) LIKE "%icenticaftor%" OR ... | [{'UUID': 'DrugGeneTargets_v2_3554', 'drugName': 'Icenticaftor', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CFTR (ENSG00000001626)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1308 | Q59 | What is the genetic target of the small molecule drug Biperiden Hydrochloride, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Biperiden Hydrochloride is CHRM1. Biperiden Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%biperiden hydrochloride%" OR LOWER(tradeNames_string) LIKE "%biperid... | [{'UUID': 'DrugGeneTargets_v2_1550', 'drugName': 'Biperiden Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRM1 (ENSG00000168539)', 'yearOfFirstApproval': 1959, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1666 | Q59 | What is the genetic target of the small molecule drug Tubocurarine, and what is its status in clinical trials and FDA approval? | There are 5 genetic targets of the small molecule drug Tubocurarine: CHRNA1, CHRNG, CHRNB1, CHRND, and CHRNE. Tubocurarine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tubocurarine%" OR LOWER(tradeNames_string) LIKE "%tubocurarine%" OR ... | [{'UUID': 'DrugGeneTargets_v2_5100', 'drugName': 'Tubocurarine Chloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRNA1 (ENSG00000138435), CHRNG (ENSG00000196811), CHRNB1 (ENSG00000170175), CHRND (ENSG00000135902), CHRNE (ENSG00000108556)', 'yearOfFirstApproval': 1945, 'maxClinicalTrialPhase... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1270 | Q59 | What is the genetic target of the small molecule drug Bradanicline, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Bradanicline is CHRNA7. Bradanicline reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%bradanicline%" OR LOWER(tradeNames_string) LIKE "%bradanicline%" OR ... | [{'UUID': 'DrugGeneTargets_v2_2167', 'drugName': 'Bradanicline', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRNA7 (ENSG00000175344)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.493 | Q59 | What is the genetic target of the antibody drug Iph-2101, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the antibody drug Iph-2101: KIR2DL2, KIR2DL1, and KIR2DL3. Iph-2101 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%iph-2101%" OR LOWER(tradeNames_string) LIKE "%iph-2101%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_4723', 'drugName': 'Iph-2101', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'KIR2DL2 (ENSG00000275546), KIR2DL1 (ENSG00000125498), KIR2DL3 (ENSG00000243772)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_4724', ... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.565 | Q59 | What is the genetic target of the small molecule drug Dicyclomine Hydrochloride, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Dicyclomine Hydrochloride: CHRM3 and CHRM1. Dicyclomine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%dicyclomine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%dicyc... | [{'UUID': 'DrugGeneTargets_v2_2299', 'drugName': 'Dicyclomine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRM3 (ENSG00000133019), CHRM1 (ENSG00000168539)', 'yearOfFirstApproval': 1950, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2300', 'drugN... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1151 | Q59 | What is the genetic target of the antibody drug F16Sip 131I, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug F16Sip 131I is TNC. F16Sip 131I reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%f16sip 131i%" OR LOWER(tradeNames_string) LIKE "%f16sip 131i%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_3063', 'drugName': 'F16Sip 131I', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'TNC (ENSG00000041982)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1129 | Q59 | What is the genetic target of the small molecule drug Isosorbide Dinitrate, and what is its status in clinical trials and FDA approval? | There are 4 genetic targets of the small molecule drug Isosorbide Dinitrate: GUCY1B1, GUCY1B2, GUCY1A2, and GUCY1A1. Isosorbide Dinitrate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%isosorbide dinitrate%" OR LOWER(tradeNames_string) LIKE "%isosorbide... | [{'UUID': 'DrugGeneTargets_v2_1011', 'drugName': 'Isosorbide Dinitrate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'GUCY1B1 (ENSG00000061918), GUCY1B2 (ENSG00000123201), GUCY1A2 (ENSG00000152402), GUCY1A1 (ENSG00000164116)', 'yearOfFirstApproval': 1986, 'maxClinicalTrialPhase': 4, 'drugIsApprove... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.808 | Q59 | What is the genetic target of the protein drug Peptide Yy Human (3-36), and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Peptide Yy Human (3-36) is NPY2R. Peptide Yy Human (3-36) reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%peptide yy human (3-36)%" OR LOWER(tradeNames_string) LIKE "%peptide... | [{'UUID': 'DrugGeneTargets_v2_3905', 'drugName': 'Peptide Yy Human (3-36)', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'NPY2R (ENSG00000185149)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.518 | Q59 | What is the genetic target of the small molecule drug Tripelennamine, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Tripelennamine is HRH1. Tripelennamine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tripelennamine%" OR LOWER(tradeNames_string) LIKE "%tripelennamine%"... | [{'UUID': 'DrugGeneTargets_v2_2166', 'drugName': 'Tripelennamine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH1 (ENSG00000196639)', 'yearOfFirstApproval': 1948, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_703', 'drugName': 'Tripelennamine Citrate', 'drugM... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.640 | Q59 | What is the genetic target of the small molecule drug Oxybate, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Oxybate: GABBR1 and GABBR2. Oxybate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%oxybate%" OR LOWER(tradeNames_string) LIKE "%oxybate%" OR LOWER(drug... | [{'UUID': 'DrugGeneTargets_v2_2097', 'drugName': 'Calcium Oxybate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'GABBR1 (ENSG00000204681), GABBR2 (ENSG00000136928)', 'yearOfFirstApproval': 2020, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4208', 'drugName': 'S... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1480 | Q59 | What is the genetic target of the protein drug Lepirudin, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Lepirudin is F2. Lepirudin reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%lepirudin%" OR LOWER(tradeNames_string) LIKE "%lepirudin%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_249', 'drugName': 'Lepirudin', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'F2 (ENSG00000180210)', 'yearOfFirstApproval': 1998, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1789 | Q59 | What is the genetic target of the protein drug Smc021, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Smc021 is CALCR. Smc021 reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%smc021%" OR LOWER(tradeNames_string) LIKE "%smc021%" OR LOWER(drugSy... | [{'UUID': 'DrugGeneTargets_v2_59', 'drugName': 'Smc021', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'CALCR (ENSG00000004948)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1546 | Q59 | What is the genetic target of the small molecule drug Rapacuronium, and what is its status in clinical trials and FDA approval? | There are 5 genetic targets of the small molecule drug Rapacuronium: CHRNA1, CHRNG, CHRNB1, CHRND, and CHRNE. Rapacuronium reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%rapacuronium%" OR LOWER(tradeNames_string) LIKE "%rapacuronium%" OR ... | [{'UUID': 'DrugGeneTargets_v2_5014', 'drugName': 'Rapacuronium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRNA1 (ENSG00000138435), CHRNG (ENSG00000196811), CHRNB1 (ENSG00000170175), CHRND (ENSG00000135902), CHRNE (ENSG00000108556)', 'yearOfFirstApproval': 1999, 'maxClinicalTrialPhase': 4, 'dr... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1160 | Q59 | What is the genetic target of the small molecule drug Guanabenz Acetate, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Guanabenz Acetate: ADRA2A, ADRA2C, and ADRA2B. Guanabenz Acetate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%guanabenz acetate%" OR LOWER(tradeNames_string) LIKE "%guanabenz ace... | [{'UUID': 'DrugGeneTargets_v2_1472', 'drugName': 'Guanabenz Acetate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRA2A (ENSG00000150594), ADRA2C (ENSG00000184160), ADRA2B (ENSG00000274286)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.797 | Q59 | What is the genetic target of the small molecule drug Paroxetine Mesylate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Paroxetine Mesylate is SLC6A4. Paroxetine Mesylate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%paroxetine mesylate%" OR LOWER(tradeNames_string) LIKE "%paroxetine ... | [{'UUID': 'DrugGeneTargets_v2_5494', 'drugName': 'Paroxetine Mesylate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A4 (ENSG00000108576)', 'yearOfFirstApproval': 2003, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.119 | Q59 | What is the genetic target of the small molecule drug Ritodrine, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Ritodrine is ADRB2. Ritodrine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ritodrine%" OR LOWER(tradeNames_string) LIKE "%ritodrine%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_1499', 'drugName': 'Ritodrine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRB2 (ENSG00000169252)', 'yearOfFirstApproval': 1991, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_5085', 'drugName': 'Ritodrine Hydrochloride', 'drugMol... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.747 | Q59 | What is the genetic target of the cell drug Sipuleucel-T, and what is its status in clinical trials and FDA approval? | The genetic target of the cell drug Sipuleucel-T is ACP3. Sipuleucel-T reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%sipuleucel-t%" OR LOWER(tradeNames_string) LIKE "%sipuleucel-t%" OR ... | [{'UUID': 'DrugGeneTargets_v2_2303', 'drugName': 'Sipuleucel-T', 'drugMolecularType': 'Cell', 'newLinkedTargets_string': 'ACP3 (ENSG00000014257)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1691 | Q59 | What is the genetic target of the small molecule drug Ipatasertib, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Ipatasertib: AKT2, AKT3, and AKT1. Ipatasertib reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ipatasertib%" OR LOWER(tradeNames_string) LIKE "%ipatasertib%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_2935', 'drugName': 'Ipatasertib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'AKT2 (ENSG00000105221), AKT3 (ENSG00000117020), AKT1 (ENSG00000142208)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1090 | Q59 | What is the genetic target of the small molecule drug Sodium Dichloroacetate, and what is its status in clinical trials and FDA approval? | There are 4 genetic targets of the small molecule drug Sodium Dichloroacetate: PDK2, PDK3, PDK4, and PDK1. Sodium Dichloroacetate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%sodium dichloroacetate%" OR LOWER(tradeNames_string) LIKE "%sodium d... | [{'UUID': 'DrugGeneTargets_v2_2764', 'drugName': 'Sodium Dichloroacetate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PDK2 (ENSG00000005882), PDK3 (ENSG00000067992), PDK4 (ENSG00000004799), PDK1 (ENSG00000152256)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.837 | Q59 | What is the genetic target of the small molecule drug Fluoxymesterone, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Fluoxymesterone is AR. Fluoxymesterone reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%fluoxymesterone%" OR LOWER(tradeNames_string) LIKE "%fluoxymesterone... | [{'UUID': 'DrugGeneTargets_v2_3575', 'drugName': 'Fluoxymesterone', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'AR (ENSG00000169083)', 'yearOfFirstApproval': 1956, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.122 | Q59 | What is the genetic target of the small molecule drug Physostigmine Salicylate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Physostigmine Salicylate is ACHE. Physostigmine Salicylate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%physostigmine salicylate%" OR LOWER(tradeNames_string) LIKE "%physos... | [{'UUID': 'DrugGeneTargets_v2_2899', 'drugName': 'Physostigmine Salicylate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ACHE (ENSG00000087085)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.663 | Q59 | What is the genetic target of the small molecule drug Donepezil Hydrochloride, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Donepezil Hydrochloride is ACHE. Donepezil Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%donepezil hydrochloride%" OR LOWER(tradeNames_string) LIKE "%donepez... | [{'UUID': 'DrugGeneTargets_v2_795', 'drugName': 'Donepezil Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ACHE (ENSG00000087085)', 'yearOfFirstApproval': 1996, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1908 | Q59 | What is the genetic target of the small molecule drug Dutetrabenazine, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Dutetrabenazine is SLC18A2. Dutetrabenazine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%dutetrabenazine%" OR LOWER(tradeNames_string) LIKE "%dutetrabenazine... | [{'UUID': 'DrugGeneTargets_v2_1735', 'drugName': 'Dutetrabenazine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC18A2 (ENSG00000165646)', 'yearOfFirstApproval': 2017, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.642 | Q59 | What is the genetic target of the small molecule drug Imatinib, and what is its status in clinical trials and FDA approval? | There are 4 genetic targets of the small molecule drug Imatinib: ABL1, PDGFRB, BCR, and KIT. Imatinib reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%imatinib%" OR LOWER(tradeNames_string) LIKE "%imatinib%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_3270', 'drugName': 'Imatinib Mesylate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ABL1 (ENSG00000097007), PDGFRB (ENSG00000113721), KIT (ENSG00000157404), BCR (ENSG00000186716)', 'yearOfFirstApproval': 2001, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UU... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.374 | Q59 | What is the genetic target of the antibody drug Ertumaxomab, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the antibody drug Ertumaxomab: ERBB2 and CD3E. Ertumaxomab reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ertumaxomab%" OR LOWER(tradeNames_string) LIKE "%ertumaxomab%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_2144', 'drugName': 'Ertumaxomab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'ERBB2 (ENSG00000141736), CD3E (ENSG00000198851)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_2145', 'drugName': 'Ertumaxomab', 'd... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.271 | Q59 | What is the genetic target of the small molecule drug Pitolisant Hydrochloride, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Pitolisant Hydrochloride is HRH3. Pitolisant Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%pitolisant hydrochloride%" OR LOWER(tradeNames_string) LIKE "%pitoli... | [{'UUID': 'DrugGeneTargets_v2_1676', 'drugName': 'Pitolisant Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH3 (ENSG00000101180)', 'yearOfFirstApproval': 2019, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
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