uuid stringlengths 4 8 | template_uuid stringclasses 40
values | question stringlengths 13 193 | answer stringlengths 29 2.2k | benchmark_query stringlengths 133 622 | execution_results stringlengths 2 1.14M | query_type stringclasses 2
values | sql_category stringclasses 26
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Q6.1417 | Q6 | What genes does Belinostat target when it's used to treat diffuse large B-cell lymphoma? | Belinostat has not been approved by the FDA as a treatment for diffuse large B-cell lymphoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are HDAC1, HDAC3, HDAC6, HDAC2, HDAC5, HDAC7, HDAC8, HDAC11, HDAC4, HDAC9, and HDAC10. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%belinostat%" OR LOWER(tradeNames_list) LIKE "%bel... | [{'UUID': 'DrugTargetsIndication121923_text_1079978', 'drugName': 'Belinostat', 'tradeNames_list': "['Beleodaq']", 'syns_list': "['Belinostat', 'NSC-726630', 'NSC726630', 'PX-105684', 'PXD-101', 'PXD101']", 'target': 'ENSG00000094631', 'approvedSymbol': 'HDAC6', 'approvedName': 'histone deacetylase 6', 'mesh_heading': ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1567 | Q6 | What genes does Celecoxib target when it's used to treat hepatocellular carcinoma? | Celecoxib has not been approved by the FDA as a treatment for hepatocellular carcinoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is PTGS2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%celecoxib%" OR LOWER(tradeNames_list) LIKE "%cele... | [{'UUID': 'DrugTargetsIndication121923_text_833399', 'drugName': 'Celecoxib', 'tradeNames_list': "['Celebra', 'Celebrex', 'Celecoxib', 'Elyxyb', 'Onsenal']", 'syns_list': "['Celecoxib', 'DFN-15', 'DFN15', 'NSC-719627', 'NSC-758624', 'SC-58635']", 'target': 'ENSG00000073756', 'approvedSymbol': 'PTGS2', 'approvedName': '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1311 | Q6 | What genes does Metoclopramide Hydrochloride target when it's used to treat Vomiting? | When used to treat Vomiting, the drug Metoclopramide Hydrochloride targets the genes DRD2, HTR3A, and HTR4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%metoclopramide hydrochloride%" OR LOWER(tradeName... | [{'UUID': 'DrugTargetsIndication121923_text_199671', 'drugName': 'Metoclopramide Hydrochloride', 'tradeNames_list': '[\'"clopra-""yellow"""\', \'Clopra\', \'Clopra-"Yellow"\', \'Gastrese l.a.Gastrobid continus\', \'Gastroflux\', \'Gastromax\', \'Gimoti\', \'MaxolonMaxolon sr\', \'Metoclomex\', \'Metoclopramide hydrochl... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.862 | Q6 | What genes does Pregabalin target when it's used to treat Focal-onset seizure? | When used to treat Focal-onset seizure, the drug Pregabalin targets the genes CACNA1B, CACNA1C, CACNA1S, CACNA1D, CACNA1F, CACNA2D2, CACNA2D1, CACNA1H, CACNA1G, CACNA1I, CACNA1A, CACNA2D3, CACNA2D4, CACNA1E, CACNB4, CACNB2, CACNB1, CACNB3, CACNG7, CACNG5, CACNG2, CACNG4, CACNG8, CACNG3, CACNG6, and CACNG1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%pregabalin%" OR LOWER(tradeNames_list) LIKE "%pre... | [{'UUID': 'DrugTargetsIndication121923_text_859585', 'drugName': 'Pregabalin', 'tradeNames_list': "['Alzain', 'Axalid', 'Lecaent', 'Lyrica', 'Lyrica cr', 'Pregabalin', 'Rewisca']", 'syns_list': "['CI-1008', 'NSC-759256', 'PD-144723', 'Pregabalin', 'Pregabalin mylanPregabalin sandoz', 'Pregabalin sandoz gmbh', 'Pregabal... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.591 | Q6 | What genes does Paclitaxel target when it's used to treat penile cancer? | Paclitaxel has not been approved by the FDA as a treatment for penile cancer, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are TUBB4B, TUBB1, TUBA3C, TUBA4A, TUBB3, TUBA1A, TUBB4A, TUBB8, TUBB, TUBA1B, TUBA1C, TUBA3E, TUBB2A, TUBB2B, and TUBB6. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%paclitaxel%" OR LOWER(tradeNames_list) LIKE "%pac... | [{'UUID': 'DrugTargetsIndication121923_text_839', 'drugName': 'Paclitaxel', 'tradeNames_list': "['Abraxane', 'Pacitaxel', 'Paclitaxel', 'Paxene', 'Taxol', 'Taxol 100']", 'syns_list': "['(-)-paclitaxel', 'ABI-007', 'ABI-007 COMPONENT PACLITAXEL', 'BMS 181339-01BMS-181339-01', 'Capxol', 'Cyclopax', 'DHP 107', 'DHP-107', ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.485 | Q6 | What genes does Acetaminophen target when it's used to treat muscle cramp? | When used to treat muscle cramp, the drug Acetaminophen targets the genes PTGS2, PTGS1, TRPV1, and FAAH. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%acetaminophen%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_829265', 'drugName': 'Acetaminophen', 'tradeNames_list': '[\'Abdine\', \'Acephen\', \'Acetaminophen\', \'Alvedon\', \'Angiers\', \'CalpolCalpol six plus\', \'Calpol six plus fastmelts\', \'Child lemsip\', \'CupanolDafalgan\', \'Datril\', \'Disprol\', \'Disprol infant\', \'Dis... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1473 | Q6 | What genes does Bortezomib target when it's used to treat Central Nervous System Neoplasm? | Bortezomib has not been approved by the FDA as a treatment for Central Nervous System Neoplasm, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are PSMD1, PSMB2, PSMB1, PSMB5, PSMB8, PSMB9, PSMB6, PSMD14, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMA7, PSMA8, PS... | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%bortezomib%" OR LOWER(tradeNames_list) LIKE "%bor... | [{'UUID': 'DrugTargetsIndication121923_text_342305', 'drugName': 'Bortezomib', 'tradeNames_list': "['Velcade']", 'syns_list': "['Bortezomib', 'Bortezomib accord', 'Bortezomib hydrate', 'LDP-341NSC-681239', 'PS-341', 'Velcade']", 'target': 'ENSG00000126067', 'approvedSymbol': 'PSMB2', 'approvedName': 'proteasome 20S sub... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1784 | Q6 | What genes does Levonorgestrel target when it's used to treat ovarian carcinoma? | Levonorgestrel has not been approved by the FDA as a treatment for ovarian carcinoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is PGR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%levonorgestrel%" OR LOWER(tradeNames_list) LIKE "... | [{'UUID': 'DrugTargetsIndication121923_text_940250', 'drugName': 'Levonorgestrel', 'tradeNames_list': "['Athentia next', 'Emerres', 'Emerres una', 'Ezinelle', 'Fallback soloHer style', 'Isteranda', 'Jadelle', 'Jaydess', 'Kyleena', 'LevonelleLevonelle one step', 'Levonelle-2', 'Levonorgestrel', 'Levosert', 'LilettaMicro... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.644 | Q6 | What genes does Bupivacaine target when it's used to treat pancreatic carcinoma? | Bupivacaine has not been approved by the FDA as a treatment for pancreatic carcinoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is SCN4A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%bupivacaine%" OR LOWER(tradeNames_list) LIKE "%bu... | [{'UUID': 'DrugTargetsIndication121923_text_663113', 'drugName': 'Bupivacaine', 'tradeNames_list': "['Anekain', 'Exparel', 'Marcaine', 'Posimir', 'Sensorcaine']", 'syns_list': "['Bucaine', 'Bupivacaine', 'Bupivacaine liposome', 'LIQ-865', 'LIQ865Liposomal bupivacaine', 'MarcaineRopivacaine hydrochloride impurity, bupiv... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.357 | Q6 | What genes does Liraglutide target when it's used to treat Parkinson disease? | Liraglutide has not been approved by the FDA as a treatment for Parkinson disease, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is GLP1R. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%liraglutide%" OR LOWER(tradeNames_list) LIKE "%li... | [{'UUID': 'DrugTargetsIndication121923_text_1044525', 'drugName': 'Liraglutide', 'tradeNames_list': "['Saxenda', 'Victoza']", 'syns_list': "['Liraglutide', 'Liraglutide (rdna origin)', 'Liraglutide recombinantNN-2211', 'NN-9924', 'NN2211', 'NN9924', 'NNC 90-1170', 'NNC-90-1170']", 'target': 'ENSG00000112164', 'approved... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1128 | Q6 | What genes does Desmopressin Acetate target when it's used to treat head injury? | When used to treat head injury, the drug Desmopressin Acetate targets the genes AVPR2, AVPR1A, and AVPR1B. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%desmopressin acetate%" OR LOWER(tradeNames_list) ... | [{'UUID': 'DrugTargetsIndication121923_text_694453', 'drugName': 'Desmopressin Acetate', 'tradeNames_list': "['Concentraid', 'Ddavp', 'Ddavp (needs no refrigeration)', 'DesmomeltDesmopressin acetate', 'Desmopressin acetate (needs no refrigeration)Desmopressin acetate preservative free', 'Desmospray', 'DesmotabsMinirin'... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.439 | Q6 | What genes does Acetaminophen target when it's used to treat pharyngitis? | When used to treat pharyngitis, the drug Acetaminophen targets the genes PTGS2, PTGS1, TRPV1, and FAAH. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%acetaminophen%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_829267', 'drugName': 'Acetaminophen', 'tradeNames_list': '[\'Abdine\', \'Acephen\', \'Acetaminophen\', \'Alvedon\', \'Angiers\', \'CalpolCalpol six plus\', \'Calpol six plus fastmelts\', \'Child lemsip\', \'CupanolDafalgan\', \'Datril\', \'Disprol\', \'Disprol infant\', \'Dis... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1121 | Q6 | What genes does Diclofenac target when it's used to treat rheumatic disease? | When used to treat rheumatic disease, the drug Diclofenac targets the genes PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%diclofenac%" OR LOWER(tradeNames_list) LIKE "%dic... | [{'UUID': 'DrugTargetsIndication121923_text_837131', 'drugName': 'Diclofenac', 'tradeNames_list': "['Cambia', 'Voltaren', 'Voltaren Ophthalmic', 'Voltaren Xr', 'ZorvolexZorvolex capsules']", 'syns_list': "['Arthrotec', 'Cataflam', 'Diclofenac', 'Diclofenac acidDiclofenac free acid', 'LAS-41007', 'LAS41007', 'Las41007',... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1103 | Q6 | What genes does Simvastatin target when it's used to treat type 2 diabetes mellitus? | When used to treat type 2 diabetes mellitus, the drug Simvastatin targets the gene HMGCR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%simvastatin%" OR LOWER(tradeNames_list) LIKE "%si... | [{'UUID': 'DrugTargetsIndication121923_text_1103903', 'drugName': 'Simvastatin', 'tradeNames_list': "['Flolipid', 'Lacersa', 'Ranzolont', 'Simvador', 'Simvastatin', 'ZocorZocor heart-pro']", 'syns_list': "['C10AA01', 'MK-0733', 'MK-733', 'NSC-758706', 'SimvastatinSimvastatin hydroxy acid', 'Synvinolin']", 'target': 'EN... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1348 | Q6 | What genes does Apremilast target when it's used to treat psoriatic arthritis? | When used to treat psoriatic arthritis, the drug Apremilast targets the genes PDE4A, PDE4D, PDE4B, and PDE4C. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%apremilast%" OR LOWER(tradeNames_list) LIKE "%apr... | [{'UUID': 'DrugTargetsIndication121923_text_696934', 'drugName': 'Apremilast', 'tradeNames_list': "['Otezla']", 'syns_list': "['Apremilast', 'CC-10004', 'CC10004']", 'target': 'ENSG00000065989', 'approvedSymbol': 'PDE4A', 'approvedName': 'phosphodiesterase 4A', 'mesh_heading': 'Arthritis, Psoriatic', 'efo_term': 'psori... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.597 | Q6 | What genes does Dronabinol target when it's used to treat alcohol dependence? | Dronabinol has not been approved by the FDA as a treatment for alcohol dependence, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is CNR1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dronabinol%" OR LOWER(tradeNames_list) LIKE "%dro... | [{'UUID': 'DrugTargetsIndication121923_text_1073229', 'drugName': 'Dronabinol', 'tradeNames_list': "['Dronabinol', 'Marinol', 'Syndros']", 'syns_list': "['.delta.-9-tetrahydrocannabinol', '.delta.1-thc.delta.9-tetrahydrocannabinol', '.delta.9-thc', 'ABBOTT 40566ABBOTT-40566', 'Delta-9-tetrahydrocannabinol', 'Delta-9-th... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1368 | Q6 | What genes does Bromocriptine Mesylate target when it's used to treat hypogonadism? | When used to treat hypogonadism, the drug Bromocriptine Mesylate targets the genes DRD2, DRD3, and DRD4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%bromocriptine mesylate%" OR LOWER(tradeNames_list... | [{'UUID': 'DrugTargetsIndication121923_text_201377', 'drugName': 'Bromocriptine Mesylate', 'tradeNames_list': "['Bromocriptine mesylate', 'Cycloset', 'Parlodel']", 'syns_list': "['2-bromoergocryptine mesylate', 'Bromocriptine mesilateBromocriptine mesylate', 'Bromocriptine methanesulfonate', 'CB-154CB-154 MESYLATE', 'C... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1401 | Q6 | What genes does Telmisartan target when it's used to treat myocardial infarction? | When used to treat myocardial infarction, the drug Telmisartan targets the gene AGTR1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%telmisartan%" OR LOWER(tradeNames_list) LIKE "%te... | [{'UUID': 'DrugTargetsIndication121923_text_1072711', 'drugName': 'Telmisartan', 'tradeNames_list': "['Micardis', 'Telmisartan', 'Tolura']", 'syns_list': "['BIBR 277 SE', 'BIBR-277', 'BIBR-277 SE', 'BIBR-277-SE', 'BIBR-277SEC09CA07', 'Kinzalmono', 'Pritor', 'Semintra', 'TelmisartanTelmisartan actavis', 'Telmisartan tev... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.753 | Q6 | What genes does Sorafenib Tosylate target when it's used to treat small cell lung carcinoma? | Sorafenib Tosylate has not been approved by the FDA as a treatment for small cell lung carcinoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are KDR, BRAF, FLT1, FLT3, KIT, FLT4, PDGFRB, RAF1, and RET. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%sorafenib tosylate%" OR LOWER(tradeNames_list) LI... | [{'UUID': 'DrugTargetsIndication121923_text_683320', 'drugName': 'Sorafenib Tosylate', 'tradeNames_list': "['Nexavar']", 'syns_list': "['BAY 54-9085', 'BAY-54-9085', 'Sorafenib tosilate', 'Sorafenib tosylate']", 'target': 'ENSG00000128052', 'approvedSymbol': 'KDR', 'approvedName': 'kinase insert domain receptor', 'mesh... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.259 | Q6 | What genes does Mometasone Furoate target when it's used to treat eosinophilic esophagitis? | Mometasone Furoate has not been approved by the FDA as a treatment for eosinophilic esophagitis, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%mometasone furoate%" OR LOWER(tradeNames_list) LI... | [{'UUID': 'DrugTargetsIndication121923_text_242024', 'drugName': 'Mometasone Furoate', 'tradeNames_list': "['Asmanex', 'Asmanex hfa', 'Asmanex twisthaler', 'EloconMometasone furoate', 'Nasonex', 'Nasonex 24hr allergy', 'Sinuva']", 'syns_list': "['LAS-41002', 'LAS41002', 'LYR-210', 'LYR210', 'Lyr-210', 'MometasoneMometa... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1687 | Q6 | What genes does Pemetrexed target when it's used to treat stomach neoplasm? | Pemetrexed has not been approved by the FDA as a treatment for stomach neoplasm, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are TYMS, GART, and DHFR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%pemetrexed%" OR LOWER(tradeNames_list) LIKE "%pem... | [{'UUID': 'DrugTargetsIndication121923_text_918722', 'drugName': 'Pemetrexed', 'tradeNames_list': "['Alimta', 'Pemfexy']", 'syns_list': "['LY-2315', 'LY-231514', 'LY231514', 'NSC-698037', 'Pemetrexed']", 'target': 'ENSG00000176890', 'approvedSymbol': 'TYMS', 'approvedName': 'thymidylate synthetase', 'mesh_heading': 'St... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1723 | Q6 | What genes does Sorafenib Tosylate target when it's used to treat acute myeloid leukemia? | Sorafenib Tosylate has not been approved by the FDA as a treatment for acute myeloid leukemia, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are KDR, BRAF, FLT1, FLT3, KIT, FLT4, PDGFRB, RAF1, and RET. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%sorafenib tosylate%" OR LOWER(tradeNames_list) LI... | [{'UUID': 'DrugTargetsIndication121923_text_683483', 'drugName': 'Sorafenib Tosylate', 'tradeNames_list': "['Nexavar']", 'syns_list': "['BAY 54-9085', 'BAY-54-9085', 'Sorafenib tosilate', 'Sorafenib tosylate']", 'target': 'ENSG00000157764', 'approvedSymbol': 'BRAF', 'approvedName': 'B-Raf proto-oncogene, serine/threoni... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.544 | Q6 | What genes does Iloperidone target when it's used to treat schizophrenia? | When used to treat schizophrenia, the drug Iloperidone targets the genes DRD2 and HTR2A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%iloperidone%" OR LOWER(tradeNames_list) LIKE "%il... | [{'UUID': 'DrugTargetsIndication121923_text_200107', 'drugName': 'Iloperidone', 'tradeNames_list': "['Fanapt', 'Iloperidone']", 'syns_list': "['HP 873', 'HP-873', 'Iloperidone']", 'target': 'ENSG00000149295', 'approvedSymbol': 'DRD2', 'approvedName': 'dopamine receptor D2', 'mesh_heading': 'Schizophrenia', 'efo_term': ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.792 | Q6 | What genes does Methotrexate target when it's used to treat B-cell acute lymphoblastic leukemia? | Methotrexate has not been approved by the FDA as a treatment for B-cell acute lymphoblastic leukemia, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is DHFR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%methotrexate%" OR LOWER(tradeNames_list) LIKE "%m... | [{'UUID': 'DrugTargetsIndication121923_text_1057507', 'drugName': 'Methotrexate', 'tradeNames_list': "['Amethopterin', 'Ebetrex', 'Emtexate high-pot', 'Emtexate pf', 'FolexMaxtrex', 'Methotrexate', 'Metoject', 'Mexate', 'Otrexup', 'Otrexup pfsRasuvo', 'Reditrex', 'Rheumatrex', 'Trexall', 'Zlatal']", 'syns_list': "['(r)... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1484 | Q6 | What genes does Paclitaxel target when it's used to treat breast neoplasm? | When used to treat breast neoplasm, the drug Paclitaxel targets the genes TUBB4B, TUBB1, TUBA3C, TUBA4A, TUBB3, TUBA1A, TUBB4A, TUBB8, TUBB, TUBA1B, TUBA1C, TUBA3E, TUBB2A, TUBB2B, and TUBB6. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%paclitaxel%" OR LOWER(tradeNames_list) LIKE "%pac... | [{'UUID': 'DrugTargetsIndication121923_text_4056', 'drugName': 'Paclitaxel', 'tradeNames_list': "['Abraxane', 'Pacitaxel', 'Paclitaxel', 'Paxene', 'Taxol', 'Taxol 100']", 'syns_list': "['(-)-paclitaxel', 'ABI-007', 'ABI-007 COMPONENT PACLITAXEL', 'BMS 181339-01BMS-181339-01', 'Capxol', 'Cyclopax', 'DHP 107', 'DHP-107',... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.420 | Q6 | What genes does Amlodipine Besylate target when it's used to treat essential hypertension? | Amlodipine Besylate has not been approved by the FDA as a treatment for essential hypertension, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are CACNA1C, CACNA1S, CACNA1D, and CACNA1F. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%amlodipine besylate%" OR LOWER(tradeNames_list) L... | [{'UUID': 'DrugTargetsIndication121923_text_1043731', 'drugName': 'Amlodipine Besylate', 'tradeNames_list': "['Amlodipine besylate', 'Norliqva', 'Norvasc']", 'syns_list': "['Amlodipine (as besilate)', 'Amlodipine benzenesulfonateAmlodipine besilate', 'Amlodipine besylate', 'Amlor', 'AntacalLodipressin', 'Monopina', 'NS... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1849 | Q6 | What genes does Bimatoprost target when it's used to treat hypotrichosis simplex? | When used to treat hypotrichosis simplex, the drug Bimatoprost targets the gene PTGFR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%bimatoprost%" OR LOWER(tradeNames_list) LIKE "%bi... | [{'UUID': 'DrugTargetsIndication121923_text_1149178', 'drugName': 'Bimatoprost', 'tradeNames_list': "['Bimatoprost', 'Durysta', 'Latisse', 'Lumigan']", 'syns_list': "['AGN 192024', 'AGN-192024', 'Bimatoprost', 'Prostamide']", 'target': 'ENSG00000122420', 'approvedSymbol': 'PTGFR', 'approvedName': 'prostaglandin F recep... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1920 | Q6 | What genes does Ipratropium Bromide target when it's used to treat Bronchospasm? | When used to treat Bronchospasm, the drug Ipratropium Bromide targets the gene CHRM3. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ipratropium bromide%" OR LOWER(tradeNames_list) L... | [{'UUID': 'DrugTargetsIndication121923_text_857474', 'drugName': 'Ipratropium Bromide', 'tradeNames_list': "['Atrovent', 'Atrovent aerocaps', 'Atrovent fte', 'Atrovent hfaAtrovent udvs', 'Ipratrop', 'Ipratrop steripoule', 'Ipratropium bromideRespontin', 'Rinatec', 'Tropiovent']", 'syns_list': "['Ipratropium bromide', '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1099 | Q6 | What genes does Methotrexate target when it's used to treat mycosis fungoides? | When used to treat mycosis fungoides, the drug Methotrexate targets the gene DHFR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%methotrexate%" OR LOWER(tradeNames_list) LIKE "%m... | [{'UUID': 'DrugTargetsIndication121923_text_1057596', 'drugName': 'Methotrexate', 'tradeNames_list': "['Amethopterin', 'Ebetrex', 'Emtexate high-pot', 'Emtexate pf', 'FolexMaxtrex', 'Methotrexate', 'Metoject', 'Mexate', 'Otrexup', 'Otrexup pfsRasuvo', 'Reditrex', 'Rheumatrex', 'Trexall', 'Zlatal']", 'syns_list': "['(r)... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.845 | Q6 | What genes does Lenvatinib target when it's used to treat thyroid carcinoma? | When used to treat thyroid carcinoma, the drug Lenvatinib targets the genes KDR, FLT1, and FLT4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lenvatinib%" OR LOWER(tradeNames_list) LIKE "%len... | [{'UUID': 'DrugTargetsIndication121923_text_690243', 'drugName': 'Lenvatinib Mesylate', 'tradeNames_list': "['Lenvima']", 'syns_list': "['E-7080 MESYLATE', 'E7080', 'E7080 MESYLATE', 'Lenvatinib mesilateLenvatinib mesylate', 'Lenvatinib methanesulfonate']", 'target': 'ENSG00000128052', 'approvedSymbol': 'KDR', 'approve... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.68 | Q6 | What genes does Spironolactone target when it's used to treat Acute kidney injury? | Spironolactone has not been approved by the FDA as a treatment for Acute kidney injury, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is NR3C2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%spironolactone%" OR LOWER(tradeNames_list) LIKE "... | [{'UUID': 'DrugTargetsIndication121923_text_1094526', 'drugName': 'Spironolactone', 'tradeNames_list': "['Abbolactone', 'Aldactone', 'Carospir', 'Diatensec', 'Gx spironolLaractone', 'Spiretic', 'Spiroctan 100', 'Spiroctan 25', 'Spiroctan 50Spironolactone', 'Spirospare 100', 'Spirospare 25']", 'syns_list': "['NSC-150399... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1698 | Q6 | What genes does Simvastatin target when it's used to treat stroke? | When used to treat stroke, the drug Simvastatin targets the gene HMGCR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%simvastatin%" OR LOWER(tradeNames_list) LIKE "%si... | [{'UUID': 'DrugTargetsIndication121923_text_1104106', 'drugName': 'Simvastatin', 'tradeNames_list': "['Flolipid', 'Lacersa', 'Ranzolont', 'Simvador', 'Simvastatin', 'ZocorZocor heart-pro']", 'syns_list': "['C10AA01', 'MK-0733', 'MK-733', 'NSC-758706', 'SimvastatinSimvastatin hydroxy acid', 'Synvinolin']", 'target': 'EN... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1733 | Q6 | What genes does Hydrocortisone Butyrate target when it's used to treat seborrheic dermatitis? | When used to treat seborrheic dermatitis, the drug Hydrocortisone Butyrate targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%hydrocortisone butyrate%" OR LOWER(tradeNames_lis... | [{'UUID': 'DrugTargetsIndication121923_text_243803', 'drugName': 'Hydrocortisone Butyrate', 'tradeNames_list': "['Hydrocortisone butyrate', 'Locoid', 'Locoid c', 'Locoid creloLocoid lipocream']", 'syns_list': "['Cortisol 17-butyrate', 'Hydrocortisone 17-butyrateHydrocortisone butyrate', 'Hydrocortisone-17-butyrate', 'N... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.380 | Q6 | What genes does Tafluprost target when it's used to treat glaucoma? | When used to treat glaucoma, the drug Tafluprost targets the gene PTGFR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%tafluprost%" OR LOWER(tradeNames_list) LIKE "%taf... | [{'UUID': 'DrugTargetsIndication121923_text_1149440', 'drugName': 'Tafluprost', 'tradeNames_list': "['Saflutan', 'Zioptan']", 'syns_list': "['AFP-168', 'MK-2452', 'Tafluprost']", 'target': 'ENSG00000122420', 'approvedSymbol': 'PTGFR', 'approvedName': 'prostaglandin F receptor', 'mesh_heading': 'Glaucoma, Open-Angle', '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.240 | Q6 | What genes does Dexamethasone target when it's used to treat leukemia? | When used to treat leukemia, the drug Dexamethasone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dexamethasone%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_231739', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.257 | Q6 | What genes does Erlosamide target when it's used to treat Seizure? | When used to treat Seizure, the drug Erlosamide targets the genes SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%erlosamide%" OR LOWER(tradeNames_list) LIKE "%erl... | [{'UUID': 'DrugTargetsIndication121923_text_644716', 'drugName': 'Erlosamide', 'tradeNames_list': "['Lacosamide', 'Vimpat']", 'syns_list': "['(r)-lacosamide 1', 'ADD 243037', 'ADD-243037', 'Erlosamide', 'LacosamideLacosamide cv', 'SPM 927', 'SPM-927']", 'target': 'ENSG00000144285', 'approvedSymbol': 'SCN1A', 'approvedN... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1032 | Q6 | What genes does Quazepam target when it's used to treat insomnia? | When used to treat insomnia, the drug Quazepam targets the genes GABRA1, GABRB2, GABRG2, GABRB3, GABRA4, GABRG3, GABRQ, GABRA3, GABRP, GABRD, GABRG1, GABRB1, GABRE, GABRA2, GABRA5, and GABRA6. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%quazepam%" OR LOWER(tradeNames_list) LIKE "%quaze... | [{'UUID': 'DrugTargetsIndication121923_text_964739', 'drugName': 'Quazepam', 'tradeNames_list': "['Doral']", 'syns_list': "['NSC-309702', 'Quazepam', 'Quazepam civ', 'SCH 16134', 'SCH-16134']", 'target': 'ENSG00000113327', 'approvedSymbol': 'GABRG2', 'approvedName': 'gamma-aminobutyric acid type A receptor subunit gamm... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.30 | Q6 | What genes does Carbamazepine target when it's used to treat trigeminal neuralgia? | When used to treat trigeminal neuralgia, the drug Carbamazepine targets the genes SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%carbamazepine%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_650987', 'drugName': 'Carbamazepine', 'tradeNames_list': "['Arbil mr', 'Carbagen sr', 'Carbamazepine', 'Carbatrol', 'Carnexiv', 'EpimazEpimaz ret', 'Epitol', 'Equetro', 'Sirtal ret', 'Tegretol', 'Tegretol XrTegretol chewtab', 'Tegretol prolonged release', 'Tegretol-xr', 'Teri... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.293 | Q6 | What genes does Binimetinib target when it's used to treat cutaneous melanoma? | When used to treat cutaneous melanoma, the drug Binimetinib targets the genes MAP2K2 and MAP2K1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%binimetinib%" OR LOWER(tradeNames_list) LIKE "%bi... | [{'UUID': 'DrugTargetsIndication121923_text_926782', 'drugName': 'Binimetinib', 'tradeNames_list': "['Mektovi']", 'syns_list': "['ARRY 438162', 'ARRY-162', 'ARRY-438162', 'Binimetinib', 'MEK-162', 'MEK162Mek-162', 'NVP-MEK162']", 'target': 'ENSG00000126934', 'approvedSymbol': 'MAP2K2', 'approvedName': 'mitogen-activate... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1886 | Q6 | What genes does Lenalidomide target when it's used to treat bladder tumor? | Lenalidomide has not been approved by the FDA as a treatment for bladder tumor, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are CRBN, DDB1, CUL4A, and RBX1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lenalidomide%" OR LOWER(tradeNames_list) LIKE "%l... | [{'UUID': 'DrugTargetsIndication121923_text_1106116', 'drugName': 'Lenalidomide', 'tradeNames_list': "['Revlimid']", 'syns_list': "['CC-5013', 'CDC-501', 'Lenalidomide', 'NSC-747972', 'SYP-1512']", 'target': 'ENSG00000113851', 'approvedSymbol': 'CRBN', 'approvedName': 'cereblon', 'mesh_heading': 'Urinary Bladder Neopla... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1823 | Q6 | What genes does Gabapentin target when it's used to treat Seizure? | When used to treat Seizure, the drug Gabapentin targets the genes CACNA1B, CACNA1C, CACNA1S, CACNA1D, CACNA1F, CACNA2D2, CACNA2D1, CACNA1H, CACNA1G, CACNA1I, CACNA1A, CACNA2D3, CACNA2D4, CACNA1E, CACNB4, CACNB2, CACNB1, CACNB3, CACNG7, CACNG5, CACNG2, CACNG4, CACNG8, CACNG3, CACNG6, and CACNG1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%gabapentin%" OR LOWER(tradeNames_list) LIKE "%gab... | [{'UUID': 'DrugTargetsIndication121923_text_895059', 'drugName': 'Gabapentin', 'tradeNames_list': "['Gabapentin', 'Gralise', 'Neurontin']", 'syns_list': "['CI-945', 'DM-1796', 'GOE 3450', 'GOE-3450', 'Gabapentin', 'NSC-742194NSC-759254']", 'target': 'ENSG00000148408', 'approvedSymbol': 'CACNA1B', 'approvedName': 'calci... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.620 | Q6 | What genes does Aprepitant target when it's used to treat Nausea? | When used to treat Nausea, the drug Aprepitant targets the gene TACR1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%aprepitant%" OR LOWER(tradeNames_list) LIKE "%apr... | [{'UUID': 'DrugTargetsIndication121923_text_1072779', 'drugName': 'Aprepitant', 'tradeNames_list': "['Aprepitant', 'Cinvanti', 'Emend']", 'syns_list': "['Aprepitant', 'L-754,030', 'MK-0869', 'MK-869', 'NSC-748825']", 'target': 'ENSG00000115353', 'approvedSymbol': 'TACR1', 'approvedName': 'tachykinin receptor 1', 'mesh_... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1667 | Q6 | What genes does Dexmedetomidine Hydrochloride target when it's used to treat schizoaffective disorder? | Dexmedetomidine Hydrochloride has not been approved by the FDA as a treatment for schizoaffective disorder, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are ADRA2A, ADRA2C, and ADRA2B. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dexmedetomidine hydrochloride%" OR LOWER(tradeNam... | [{'UUID': 'DrugTargetsIndication121923_text_1025770', 'drugName': 'Dexmedetomidine Hydrochloride', 'tradeNames_list': "['Dexmedetomidine hydrochloride', 'Igalmi', 'Precedex']", 'syns_list': "['Cepedex', 'Dexdomitor', 'Dexdor', 'Dexmedetomidine hclDexmedetomidine hydrochloride', 'Igalmi', 'Sedadex', 'Sileo']", 'target':... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.850 | Q6 | What genes does Gabapentin Enacarbil target when it's used to treat epilepsy? | When used to treat epilepsy, the drug Gabapentin Enacarbil targets the genes CACNA1B, CACNA1C, CACNA1S, CACNA1D, CACNA1F, CACNA2D2, CACNA2D1, CACNA1H, CACNA1G, CACNA1I, CACNA1A, CACNA2D3, CACNA2D4, CACNA1E, CACNB4, CACNB2, CACNB1, CACNB3, CACNG7, CACNG5, CACNG2, CACNG4, CACNG8, CACNG3, CACNG6, and CACNG1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%gabapentin enacarbil%" OR LOWER(tradeNames_list) ... | [{'UUID': 'DrugTargetsIndication121923_text_891809', 'drugName': 'Gabapentin Enacarbil', 'tradeNames_list': "['Horizant']", 'syns_list': "['ASP-8825', 'ASP8825', 'GSK1838262', 'Gabapentin enacarbilGabapentin encarbil', 'Gsk-1838262', 'XP 13512', 'XP-13512', 'XP13512']", 'target': 'ENSG00000148408', 'approvedSymbol': 'C... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.215 | Q6 | What genes does Guanfacine Hydrochloride target when it's used to treat attention deficit hyperactivity disorder? | When used to treat attention deficit hyperactivity disorder, the drug Guanfacine Hydrochloride targets the genes ADRA2A, ADRA2C, and ADRA2B. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%guanfacine hydrochloride%" OR LOWER(tradeNames_li... | [{'UUID': 'DrugTargetsIndication121923_text_1025307', 'drugName': 'Guanfacine Hydrochloride', 'tradeNames_list': "['Akfen', 'Estulic', 'Guanfacine hydrochloride', 'Intuniv', 'Tenex']", 'syns_list': "['BS 100-141', 'BS-100-141', 'Guafacine hydrochloride', 'Guanfacine hclGuanfacine hydrochloride', 'SPD503']", 'target': '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.524 | Q6 | What genes does Prednisone target when it's used to treat pulmonary tuberculosis? | When used to treat pulmonary tuberculosis, the drug Prednisone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%prednisone%" OR LOWER(tradeNames_list) LIKE "%pre... | [{'UUID': 'DrugTargetsIndication121923_text_218703', 'drugName': 'Prednisone', 'tradeNames_list': "['Cortan', 'Cortancyl', 'Decortisyl', 'Delta-dome', 'Deltasone', 'FernisoneLiquid pred', 'Lodotra', 'Meticorten', 'Orasone', 'Paracort', 'Prednicen-mPrednisone', 'Prednisone intensol', 'Rayos', 'Servisone', 'Sterapred']",... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.477 | Q6 | What genes does Nizatidine target when it's used to treat Esophagitis? | When used to treat Esophagitis, the drug Nizatidine targets the gene HRH2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%nizatidine%" OR LOWER(tradeNames_list) LIKE "%niz... | [{'UUID': 'DrugTargetsIndication121923_text_1100309', 'drugName': 'Nizatidine', 'tradeNames_list': "['Axid', 'Axid ar', 'Nizatidine', 'Zinga 150', 'Zinga 300']", 'syns_list': "['Acinon', 'LY 139037', 'LY-139037', 'NSC-759289', 'Nizatidine']", 'target': 'ENSG00000113749', 'approvedSymbol': 'HRH2', 'approvedName': 'hista... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1327 | Q6 | What genes does Ranolazine target when it's used to treat cardiovascular disease? | When used to treat cardiovascular disease, the drug Ranolazine targets the genes SCN5A and SCN4A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ranolazine%" OR LOWER(tradeNames_list) LIKE "%ran... | [{'UUID': 'DrugTargetsIndication121923_text_662707', 'drugName': 'Ranolazine', 'tradeNames_list': "['Aspruzyo sprinkle', 'Ranexa', 'Ranolazine']", 'syns_list': "['Aspruzyo', 'CVT-303', 'NSC-759100', 'RS-43285-003', 'Ran d', 'Ranolazine']", 'target': 'ENSG00000183873', 'approvedSymbol': 'SCN5A', 'approvedName': 'sodium ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1433 | Q6 | What genes does Doxycycline Hyclate target when it's used to treat acne? | When used to treat acne, the drug Doxycycline Hyclate targets the genes MMP7, MMP1, MMP13, and MMP8. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%doxycycline hyclate%" OR LOWER(tradeNames_list) L... | [{'UUID': 'DrugTargetsIndication121923_text_1036879', 'drugName': 'Doxycycline Hyclate', 'tradeNames_list': "['Acticlate', 'Acticlate cap', 'Alodox', 'Atridox', 'Cyclodox', 'Demix 100Demix 50', 'Doryx', 'Doryx mpc', 'Doxatet', 'Doxy', 'Doxy 100', 'Doxy 200Doxy-Caps', 'Doxy-lemmon', 'Doxychel hyclate', 'Doxycycline hycl... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.123 | Q6 | What genes does Dexamethasone target when it's used to treat ulcerative colitis? | When used to treat ulcerative colitis, the drug Dexamethasone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dexamethasone%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_227754', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1351 | Q6 | What genes does Aspirin target when it's used to treat chronic kidney disease? | Aspirin has not been approved by the FDA as a treatment for chronic kidney disease, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%aspirin%" OR LOWER(tradeNames_list) LIKE "%aspiri... | [{'UUID': 'DrugTargetsIndication121923_text_834378', 'drugName': 'Aspirin', 'tradeNames_list': "['8-hour bayer', 'Acetosalic Acid', 'Acetylsalic acidAcetylsalicylic Acid', 'Alka rapid', 'Anadin all night', 'Angettes 75Aspirin', 'Aspro clr', 'Bayer extra strength aspirin for migraine painDanamep', 'Disprin cv', 'Disprin... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1942 | Q6 | What genes does Midostaurin target when it's used to treat leukemia? | Midostaurin has not been approved by the FDA as a treatment for leukemia, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are KDR, FLT3, KIT, PDGFRB, PDGFRA, PRKCE, PRKCB, PRKD3, PRKCI, PRKCA, PRKCG, PRKCD, PRKCZ, PRKCH, PRKD1, and PRKCQ. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%midostaurin%" OR LOWER(tradeNames_list) LIKE "%mi... | [{'UUID': 'DrugTargetsIndication121923_text_667598', 'drugName': 'Midostaurin', 'tradeNames_list': "['Rydapt']", 'syns_list': "['CGP 41251', 'CGP-41251', 'Midostaurin', 'NSC-656576', 'NVP-PKC412', 'PKC 412PKC-412', 'Pkc-412']", 'target': 'ENSG00000154229', 'approvedSymbol': 'PRKCA', 'approvedName': 'protein kinase C al... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1371 | Q6 | What genes does Cinacalcet Hydrochloride target when it's used to treat carcinoma? | When used to treat carcinoma, the drug Cinacalcet Hydrochloride targets the gene CASR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%cinacalcet hydrochloride%" OR LOWER(tradeNames_li... | [{'UUID': 'DrugTargetsIndication121923_text_1149031', 'drugName': 'Cinacalcet Hydrochloride', 'tradeNames_list': "['Mimpara', 'Sensipar']", 'syns_list': "['AMG-073', 'AMG-073 HCL', 'AMG073 HCL', 'AMG073 HYDROCHLORIDECinacalcet hcl', 'Cinacalcet hydrochloride']", 'target': 'ENSG00000036828', 'approvedSymbol': 'CASR', 'a... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1171 | Q6 | What genes does Apalutamide target when it's used to treat prostate adenocarcinoma? | When used to treat prostate adenocarcinoma, the drug Apalutamide targets the gene AR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%apalutamide%" OR LOWER(tradeNames_list) LIKE "%ap... | [{'UUID': 'DrugTargetsIndication121923_text_921899', 'drugName': 'Apalutamide', 'tradeNames_list': "['Erleada']", 'syns_list': "['ARN-509', 'Apalutamide', 'Arn-509', 'JNJ-56021927']", 'target': 'ENSG00000169083', 'approvedSymbol': 'AR', 'approvedName': 'androgen receptor', 'mesh_heading': 'Prostatic Neoplasms', 'efo_te... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.138 | Q6 | What genes does Ixazomib target when it's used to treat triple-negative breast cancer? | Ixazomib has not been approved by the FDA as a treatment for triple-negative breast cancer, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are PSMD1, PSMB2, PSMB1, PSMB5, PSMB8, PSMB9, PSMB6, PSMD14, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMA7, PSMA8, PSMB10... | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ixazomib%" OR LOWER(tradeNames_list) LIKE "%ixazo... | [{'UUID': 'DrugTargetsIndication121923_text_246441', 'drugName': 'Ixazomib', 'tradeNames_list': "['Ninlaro']", 'syns_list': "['Ixazomib', 'MLN-2238', 'MLN-9708 FREE BASE', 'MLN2238']", 'target': 'ENSG00000173692', 'approvedSymbol': 'PSMD1', 'approvedName': 'proteasome 26S subunit, non-ATPase 1', 'mesh_heading': 'Triple... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1134 | Q6 | What genes does Famotidine target when it's used to treat cancer? | Famotidine has not been approved by the FDA as a treatment for cancer, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is HRH2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%famotidine%" OR LOWER(tradeNames_list) LIKE "%fam... | [{'UUID': 'DrugTargetsIndication121923_text_1100324', 'drugName': 'Famotidine', 'tradeNames_list': "['Famotidine', 'Famotidine preservative freeFamotidine preservative free (pharmacy bulk)', 'Fluxid', 'PepcidPepcid ac', 'Pepcid preservative free', 'Pepcid rpd']", 'syns_list': "['Amfamox', 'Fadul', 'Famodil', 'Famosan',... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1874 | Q6 | What genes does Tafamidis Meglumine target when it's used to treat cardiomyopathy? | When used to treat cardiomyopathy, the drug Tafamidis Meglumine targets the gene TTR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%tafamidis meglumine%" OR LOWER(tradeNames_list) L... | [{'UUID': 'DrugTargetsIndication121923_text_1097629', 'drugName': 'Tafamidis Meglumine', 'tradeNames_list': "['Vyndaqel']", 'syns_list': "['FX-1006A', 'Tafamidis meglumine']", 'target': 'ENSG00000118271', 'approvedSymbol': 'TTR', 'approvedName': 'transthyretin', 'mesh_heading': 'Cardiomyopathies', 'efo_term': 'cardiomy... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1241 | Q6 | What genes does Temsirolimus target when it's used to treat neoplasm? | When used to treat neoplasm, the drug Temsirolimus targets the gene FKBP1A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%temsirolimus%" OR LOWER(tradeNames_list) LIKE "%t... | [{'UUID': 'DrugTargetsIndication121923_text_1090789', 'drugName': 'Temsirolimus', 'tradeNames_list': "['Torisel']", 'syns_list': "['CCI-779', 'Temsirolimus']", 'target': 'ENSG00000088832', 'approvedSymbol': 'FKBP1A', 'approvedName': 'FKBP prolyl isomerase 1A', 'mesh_heading': 'Neoplasms', 'efo_term': 'neoplasm', 'yearO... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1338 | Q6 | What genes does Bupivacaine target when it's used to treat Hernia? | When used to treat Hernia, the drug Bupivacaine targets the gene SCN4A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%bupivacaine%" OR LOWER(tradeNames_list) LIKE "%bu... | [{'UUID': 'DrugTargetsIndication121923_text_663605', 'drugName': 'Bupivacaine', 'tradeNames_list': "['Anekain', 'Exparel', 'Marcaine', 'Posimir', 'Sensorcaine']", 'syns_list': "['Bucaine', 'Bupivacaine', 'Bupivacaine liposome', 'LIQ-865', 'LIQ865Liposomal bupivacaine', 'MarcaineRopivacaine hydrochloride impurity, bupiv... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.958 | Q6 | What genes does Triamcinolone Acetonide target when it's used to treat fungal infectious disease? | When used to treat fungal infectious disease, the drug Triamcinolone Acetonide targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%triamcinolone acetonide%" OR LOWER(tradeNames_lis... | [{'UUID': 'DrugTargetsIndication121923_text_222211', 'drugName': 'Triamcinolone Acetonide', 'tradeNames_list': "['Adcortyl', 'Adcortyl in orabase', 'Allernaze', 'Aristocort', 'Aristocort aAristogel', 'Audicort', 'Aureocort', 'Azmacort', 'Flutex', 'Gppe ear dps capGppe ear oint', 'Kenacort', 'Kenalog', 'Kenalog in oraba... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.929 | Q6 | What genes does Amlodipine Besylate target when it's used to treat coronary artery disease? | When used to treat coronary artery disease, the drug Amlodipine Besylate targets the genes CACNA1C, CACNA1S, CACNA1D, and CACNA1F. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%amlodipine besylate%" OR LOWER(tradeNames_list) L... | [{'UUID': 'DrugTargetsIndication121923_text_1043737', 'drugName': 'Amlodipine Besylate', 'tradeNames_list': "['Amlodipine besylate', 'Norliqva', 'Norvasc']", 'syns_list': "['Amlodipine (as besilate)', 'Amlodipine benzenesulfonateAmlodipine besilate', 'Amlodipine besylate', 'Amlor', 'AntacalLodipressin', 'Monopina', 'NS... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.112 | Q6 | What genes does Fluocinolone Acetonide target when it's used to treat uveitis? | When used to treat uveitis, the drug Fluocinolone Acetonide targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fluocinolone acetonide%" OR LOWER(tradeNames_list... | [{'UUID': 'DrugTargetsIndication121923_text_242257', 'drugName': 'Fluocinolone Acetonide', 'tradeNames_list': "['Capex', 'Derma-smoothe/fs', 'Dermotic', 'Fluocet', 'Fluocinolone acetonideFluonid', 'Fluotrex', 'Fs shampoo', 'Iluvien', 'Retisert', 'SynalarSynalar fte', 'Synalar-c', 'Synalar-hp', 'Synalar-n', 'Synandone',... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1240 | Q6 | What genes does Pralsetinib target when it's used to treat cancer? | When used to treat cancer, the drug Pralsetinib targets the genes RET, CCDC6, and KIF5B. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%pralsetinib%" OR LOWER(tradeNames_list) LIKE "%pr... | [{'UUID': 'DrugTargetsIndication121923_text_944311', 'drugName': 'Pralsetinib', 'tradeNames_list': "['Gavreto']", 'syns_list': "[':pralsetinib', 'BLU-123244', 'BLU-667', 'BLU123244', 'Blu-667', 'PralsetinibX-581238', 'X581238']", 'target': 'ENSG00000165731', 'approvedSymbol': 'RET', 'approvedName': 'ret proto-oncogene'... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1921 | Q6 | What genes does Naproxen Sodium target when it's used to treat juvenile idiopathic arthritis? | When used to treat juvenile idiopathic arthritis, the drug Naproxen Sodium targets the genes PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%naproxen sodium%" OR LOWER(tradeNames_list) LIKE ... | [{'UUID': 'DrugTargetsIndication121923_text_838130', 'drugName': 'Naproxen Sodium', 'tradeNames_list': "['Aleve', 'Anaprox', 'Anaprox ds', 'Naprelan', 'Naproxen sodium', 'Synflex']", 'syns_list': "['BAY-117031', 'BAY117031', 'BAYH6689', 'Naproxen sodiumNaproxen sodium anhydrous', 'Naproxen sodium salt', 'RS-3650']", 't... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1963 | Q6 | What genes does Ripretinib target when it's used to treat neoplasm? | When used to treat neoplasm, the drug Ripretinib targets the genes KIT and PDGFRA. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ripretinib%" OR LOWER(tradeNames_list) LIKE "%rip... | [{'UUID': 'DrugTargetsIndication121923_text_933995', 'drugName': 'Ripretinib', 'tradeNames_list': "['Qinlock']", 'syns_list': "['DCC-2618', 'Dcc-2618', 'Ripretinib']", 'target': 'ENSG00000157404', 'approvedSymbol': 'KIT', 'approvedName': 'KIT proto-oncogene, receptor tyrosine kinase', 'mesh_heading': 'Neoplasms', 'efo_... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.214 | Q6 | What genes does Semaglutide target when it's used to treat type 2 diabetes mellitus? | When used to treat type 2 diabetes mellitus, the drug Semaglutide targets the gene GLP1R. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%semaglutide%" OR LOWER(tradeNames_list) LIKE "%se... | [{'UUID': 'DrugTargetsIndication121923_text_1051909', 'drugName': 'Semaglutide', 'tradeNames_list': "['Ozempic', 'Rybelsus', 'Wegovy']", 'syns_list': "['NN-9535', 'NN9535', 'NNC 0113-0217', 'NNC-0113-0217', 'Nn9535', 'Semaglutide']", 'target': 'ENSG00000112164', 'approvedSymbol': 'GLP1R', 'approvedName': 'glucagon like... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.999 | Q6 | What genes does Dihydroergotamine Mesylate target when it's used to treat migraine disorder? | When used to treat migraine disorder, the drug Dihydroergotamine Mesylate targets the gene HTR1D. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dihydroergotamine mesylate%" OR LOWER(tradeNames_... | [{'UUID': 'DrugTargetsIndication121923_text_937542', 'drugName': 'Dihydroergotamine Mesylate', 'tradeNames_list': "['D.h.e. 45', 'Diergo', 'Dihydergot', 'Dihydroergotamine mesylate', 'TonopanTrudhesa']", 'syns_list': "['DHE-45', 'Dihydroergotamine MethanesulfonateDihydroergotamine mesilate', 'Dihydroergotamine mesylate... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1269 | Q6 | What genes does Sitagliptin Phosphate target when it's used to treat type 2 diabetes mellitus? | When used to treat type 2 diabetes mellitus, the drug Sitagliptin Phosphate targets the gene DPP4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%sitagliptin phosphate%" OR LOWER(tradeNames_list)... | [{'UUID': 'DrugTargetsIndication121923_text_933072', 'drugName': 'Sitagliptin Phosphate', 'tradeNames_list': "['Janumet Xr', 'Januvia']", 'syns_list': "['Glactiv', 'MK-0431', 'MK0431', 'ONO-5435', 'Sitagliptin monophosphateSitagliptin monophosphate anhydrousSitagliptin monophosphate monohydrate', 'Sitagliptin phosphate... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.592 | Q6 | What genes does Bosentan target when it's used to treat congenital heart disease? | When used to treat congenital heart disease, the drug Bosentan targets the genes EDNRA and EDNRB. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%bosentan%" OR LOWER(tradeNames_list) LIKE "%bosen... | [{'UUID': 'DrugTargetsIndication121923_text_1084292', 'drugName': 'Bosentan', 'tradeNames_list': "['Tracleer']", 'syns_list': "['Anhydrous bosentan', 'Bosentan', 'Bosentan anhydrous', 'Bosentan hydrateBosentan monohydrate', 'RO 47-0203/029', 'RO-47-0203-029', 'RO-470203029']", 'target': 'ENSG00000136160', 'approvedSymb... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1391 | Q6 | What genes does Dexamethasone target when it's used to treat congenital adrenal hyperplasia? | When used to treat congenital adrenal hyperplasia, the drug Dexamethasone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dexamethasone%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_226954', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1450 | Q6 | What genes does Metoclopramide Hydrochloride target when it's used to treat post operative nausea and vomiting? | When used to treat post operative nausea and vomiting, the drug Metoclopramide Hydrochloride targets the genes DRD2, HTR3A, and HTR4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%metoclopramide hydrochloride%" OR LOWER(tradeName... | [{'UUID': 'DrugTargetsIndication121923_text_199703', 'drugName': 'Metoclopramide Hydrochloride', 'tradeNames_list': '[\'"clopra-""yellow"""\', \'Clopra\', \'Clopra-"Yellow"\', \'Gastrese l.a.Gastrobid continus\', \'Gastroflux\', \'Gastromax\', \'Gimoti\', \'MaxolonMaxolon sr\', \'Metoclomex\', \'Metoclopramide hydrochl... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.279 | Q6 | What genes does Carvedilol target when it's used to treat cardiovascular disease? | When used to treat cardiovascular disease, the drug Carvedilol targets the genes ADRA1A, ADRB2, ADRB1, ADRB3, ADRA1D, and ADRA1B. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%carvedilol%" OR LOWER(tradeNames_list) LIKE "%car... | [{'UUID': 'DrugTargetsIndication121923_text_357135', 'drugName': 'Carvedilol', 'tradeNames_list': "['Carvedilol', 'Coreg', 'Coreg CR', 'Eucardic 12.5', 'Eucardic 25Eucardic 3.125', 'Eucardic 6.25']", 'syns_list': "['BM 14.190', 'BM-14-190', 'BM-14.190', 'BM-14190', 'C07AG02', 'CarvedilolCoronis', 'DQ-2466', 'Dilatrend'... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1507 | Q6 | What genes does Dantrolene Sodium target when it's used to treat Spasticity? | When used to treat Spasticity, the drug Dantrolene Sodium targets the genes RYR3 and RYR1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dantrolene sodium%" OR LOWER(tradeNames_list) LIK... | [{'UUID': 'DrugTargetsIndication121923_text_1100263', 'drugName': 'Dantrolene Sodium', 'tradeNames_list': "['Dantrium', 'Dantrolene sodium', 'Revonto', 'Ryanodex']", 'syns_list': "['Dantamacrin', 'Dantrolen', 'Dantrolene sodiumDantrolene sodium heptahydrate', 'Dantrolene sodium hydrateDantrolene sodium salt hemiheptahy... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1328 | Q6 | What genes does Apremilast target when it's used to treat Vitiligo? | Apremilast has not been approved by the FDA as a treatment for Vitiligo, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are PDE4A, PDE4D, PDE4B, and PDE4C. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%apremilast%" OR LOWER(tradeNames_list) LIKE "%apr... | [{'UUID': 'DrugTargetsIndication121923_text_696917', 'drugName': 'Apremilast', 'tradeNames_list': "['Otezla']", 'syns_list': "['Apremilast', 'CC-10004', 'CC10004']", 'target': 'ENSG00000065989', 'approvedSymbol': 'PDE4A', 'approvedName': 'phosphodiesterase 4A', 'mesh_heading': 'Vitiligo', 'efo_term': 'Vitiligo', 'yearO... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1271 | Q6 | What genes does Baclofen target when it's used to treat Spasticity? | When used to treat Spasticity, the drug Baclofen targets the genes GABBR1 and GABBR2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%baclofen%" OR LOWER(tradeNames_list) LIKE "%baclo... | [{'UUID': 'DrugTargetsIndication121923_text_1193243', 'drugName': 'Baclofen', 'tradeNames_list': "['Baclofen', 'Baclospas-10', 'Fleqsuvy', 'Gablofen', 'Kemstro', 'LioresalLioresal intrath', 'Lyflex', 'Lyvispah', 'Ozobax']", 'syns_list': "['(rs)-baclofen', 'BA-34,647', 'BA-34647', 'Baclofen', 'Fleqsuvy', 'LyvispahNSC-75... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1820 | Q6 | What genes does Dexamethasone target when it's used to treat Nasal congestion? | When used to treat Nasal congestion, the drug Dexamethasone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dexamethasone%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_227738', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.273 | Q6 | What genes does Tiotropium Bromide target when it's used to treat asthma? | When used to treat asthma, the drug Tiotropium Bromide targets the gene CHRM3. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%tiotropium bromide%" OR LOWER(tradeNames_list) LI... | [{'UUID': 'DrugTargetsIndication121923_text_857884', 'drugName': 'Tiotropium Bromide', 'tradeNames_list': "['Spiriva', 'Spiriva respimat']", 'syns_list': "['BA 679 BR', 'BA-679 BR', 'BA-679-BR', 'BA-679BR', 'Tiotropium bromideTiotropium bromide anhydrous', 'Tiotropium bromide hydrateTiotropium bromide monohydrate']", '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1863 | Q6 | What genes does Desvenlafaxine Succinate target when it's used to treat major depressive disorder? | When used to treat major depressive disorder, the drug Desvenlafaxine Succinate targets the genes SLC6A4 and SLC6A2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%desvenlafaxine succinate%" OR LOWER(tradeNames_li... | [{'UUID': 'DrugTargetsIndication121923_text_206754', 'drugName': 'Desvenlafaxine Succinate', 'tradeNames_list': "['Desvenlafaxine succinate', 'Pristiq']", 'syns_list': "['DVS-233', 'Desvenlafaxine succinate', 'Desvenlafaxine succinate anhydrousDesvenlafaxine succinate hydrate', 'Desvenlafaxine succinate monohydrateDvs ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.578 | Q6 | What genes does Docetaxel target when it's used to treat neoplasm? | When used to treat neoplasm, the drug Docetaxel targets the genes TUBB4B, TUBB1, TUBA3C, TUBA4A, TUBB3, TUBA1A, TUBB4A, TUBB8, TUBB, TUBA1B, TUBA1C, TUBA3E, TUBB2A, TUBB2B, and TUBB6. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%docetaxel%" OR LOWER(tradeNames_list) LIKE "%doce... | [{'UUID': 'DrugTargetsIndication121923_text_96961', 'drugName': 'Docetaxel', 'tradeNames_list': "['Docefrez', 'Docetaxel', 'Taxceus', 'Taxotere']", 'syns_list': "['Bind 014', 'CKD-810', 'Docetaxel', 'Docetaxel (as trihydrate)Docetaxel anhydrous', 'Docetaxel hydrate', 'Docetaxel trihydrateNSC-628503', 'RP 56976', 'RP-56... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.638 | Q6 | What genes does Hydrocortisone target when it's used to treat dermatitis? | Hydrocortisone has not been approved by the FDA as a treatment for dermatitis, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%hydrocortisone%" OR LOWER(tradeNames_list) LIKE "... | [{'UUID': 'DrugTargetsIndication121923_text_217660', 'drugName': 'Prednisone', 'tradeNames_list': "['Cortan', 'Cortancyl', 'Decortisyl', 'Delta-dome', 'Deltasone', 'FernisoneLiquid pred', 'Lodotra', 'Meticorten', 'Orasone', 'Paracort', 'Prednicen-mPrednisone', 'Prednisone intensol', 'Rayos', 'Servisone', 'Sterapred']",... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.713 | Q6 | What genes does Ticagrelor target when it's used to treat myocardial infarction? | When used to treat myocardial infarction, the drug Ticagrelor targets the gene P2RY12. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ticagrelor%" OR LOWER(tradeNames_list) LIKE "%tic... | [{'UUID': 'DrugTargetsIndication121923_text_920755', 'drugName': 'Ticagrelor', 'tradeNames_list': "['Brilinta', 'Brilique']", 'syns_list': "['AR-C126532XX', 'AZD-6140', 'AZD6140', 'Possia', 'Ticagrelor']", 'target': 'ENSG00000169313', 'approvedSymbol': 'P2RY12', 'approvedName': 'purinergic receptor P2Y12', 'mesh_headin... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1529 | Q6 | What genes does Vemurafenib target when it's used to treat cutaneous melanoma? | When used to treat cutaneous melanoma, the drug Vemurafenib targets the gene BRAF. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%vemurafenib%" OR LOWER(tradeNames_list) LIKE "%ve... | [{'UUID': 'DrugTargetsIndication121923_text_752200', 'drugName': 'Vemurafenib', 'tradeNames_list': "['Zelboraf']", 'syns_list': "['PLX-4032', 'PLX4032', 'RG 7204', 'RG-7204', 'RO 5185426', 'RO-51-85426RO-5185426', 'Vemurafenib']", 'target': 'ENSG00000157764', 'approvedSymbol': 'BRAF', 'approvedName': 'B-Raf proto-oncog... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.627 | Q6 | What genes does Obeticholic Acid target when it's used to treat Cholangitis? | When used to treat Cholangitis, the drug Obeticholic Acid targets the gene NR1H4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%obeticholic acid%" OR LOWER(tradeNames_list) LIKE... | [{'UUID': 'DrugTargetsIndication121923_text_1104516', 'drugName': 'Obeticholic Acid', 'tradeNames_list': "['Ocaliva']", 'syns_list': "['6-ecdca', '6-ethylchenodeoxycholic acid', 'DSP-1747', 'INT-747Obeticholic acid']", 'target': 'ENSG00000012504', 'approvedSymbol': 'NR1H4', 'approvedName': 'nuclear receptor subfamily 1... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1991 | Q6 | What genes does Apalutamide target when it's used to treat prostate carcinoma? | When used to treat prostate carcinoma, the drug Apalutamide targets the gene AR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%apalutamide%" OR LOWER(tradeNames_list) LIKE "%ap... | [{'UUID': 'DrugTargetsIndication121923_text_921871', 'drugName': 'Apalutamide', 'tradeNames_list': "['Erleada']", 'syns_list': "['ARN-509', 'Apalutamide', 'Arn-509', 'JNJ-56021927']", 'target': 'ENSG00000169083', 'approvedSymbol': 'AR', 'approvedName': 'androgen receptor', 'mesh_heading': 'Prostatic Neoplasms, Castrati... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.813 | Q6 | What genes does Bremelanotide Acetate target when it's used to treat mental or behavioural disorder? | When used to treat mental or behavioural disorder, the drug Bremelanotide Acetate targets the gene MC4R. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%bremelanotide acetate%" OR LOWER(tradeNames_list)... | [{'UUID': 'DrugTargetsIndication121923_text_1025287', 'drugName': 'Bremelanotide Acetate', 'tradeNames_list': "['Vyleesi (autoinjector)']", 'syns_list': "['Bremelanotide acetate', 'PT 141', 'PT-141', 'Vyleesi']", 'target': 'ENSG00000166603', 'approvedSymbol': 'MC4R', 'approvedName': 'melanocortin 4 receptor', 'mesh_hea... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.309 | Q6 | What genes does Vardenafil target when it's used to treat erectile dysfunction? | When used to treat erectile dysfunction, the drug Vardenafil targets the gene PDE5A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%vardenafil%" OR LOWER(tradeNames_list) LIKE "%var... | [{'UUID': 'DrugTargetsIndication121923_text_1094112', 'drugName': 'Vardenafil Hydrochloride', 'tradeNames_list': "['Levitra', 'Staxyn', 'Vardenafil hydrochloride']", 'syns_list': "['BAY 38-9456', 'BAY-38-9456', 'Nuviva', 'Vardenafil hclVardenafil hydrochloride', 'Vardenafil hydrochloride anhydrousVardenafil hydrochlori... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.550 | Q6 | What genes does Lenvatinib target when it's used to treat glioma? | Lenvatinib has not been approved by the FDA as a treatment for glioma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are KDR, FLT1, and FLT4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lenvatinib%" OR LOWER(tradeNames_list) LIKE "%len... | [{'UUID': 'DrugTargetsIndication121923_text_690787', 'drugName': 'Lenvatinib', 'tradeNames_list': "['Kisplyx', 'Lenvima']", 'syns_list': "['E-7080', 'ER-203492-00', 'Lenvatinib']", 'target': 'ENSG00000128052', 'approvedSymbol': 'KDR', 'approvedName': 'kinase insert domain receptor', 'mesh_heading': 'Glioma', 'efo_term'... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1606 | Q6 | What genes does Indomethacin target when it's used to treat pancreatitis? | Indomethacin has not been approved by the FDA as a treatment for pancreatitis, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%indomethacin%" OR LOWER(tradeNames_list) LIKE "%i... | [{'UUID': 'DrugTargetsIndication121923_text_828395', 'drugName': 'Indomethacin', 'tradeNames_list': "['Artracin', 'Artracin sr', 'Berlind 75 ret', 'Flexin-25 continusFlexin-50 continus', 'Flexin-75 continus', 'Imbrilon', 'Indo-lemmonIndo-paed', 'Indocid ret', 'Indocid-r', 'Indocin', 'Indocin sr', 'IndodermIndoflex', 'I... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1743 | Q6 | What genes does Palonosetron Hydrochloride target when it's used to treat Chemotherapy-induced nausea and vomiting? | When used to treat Chemotherapy-induced nausea and vomiting, the drug Palonosetron Hydrochloride targets the gene HTR3A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%palonosetron hydrochloride%" OR LOWER(tradeNames_... | [{'UUID': 'DrugTargetsIndication121923_text_205524', 'drugName': 'Palonosetron Hydrochloride', 'tradeNames_list': "['Aloxi', 'Palonosetron hydrochloride']", 'syns_list': "['Palonocetron hydrochloride', 'Palonosetron (as hydrochloride)Palonosetron hcl', 'Palonosetron hydrochloride', 'RS-25259-197']", 'target': 'ENSG0000... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.50 | Q6 | What genes does Bupivacaine target when it's used to treat pregnancy? | Bupivacaine has not been approved by the FDA as a treatment for pregnancy, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is SCN4A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%bupivacaine%" OR LOWER(tradeNames_list) LIKE "%bu... | [{'UUID': 'DrugTargetsIndication121923_text_663082', 'drugName': 'Bupivacaine', 'tradeNames_list': "['Anekain', 'Exparel', 'Marcaine', 'Posimir', 'Sensorcaine']", 'syns_list': "['Bucaine', 'Bupivacaine', 'Bupivacaine liposome', 'LIQ-865', 'LIQ865Liposomal bupivacaine', 'MarcaineRopivacaine hydrochloride impurity, bupiv... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1089 | Q6 | What genes does Prednisone target when it's used to treat Aplastic anemia? | When used to treat Aplastic anemia, the drug Prednisone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%prednisone%" OR LOWER(tradeNames_list) LIKE "%pre... | [{'UUID': 'DrugTargetsIndication121923_text_218664', 'drugName': 'Prednisone', 'tradeNames_list': "['Cortan', 'Cortancyl', 'Decortisyl', 'Delta-dome', 'Deltasone', 'FernisoneLiquid pred', 'Lodotra', 'Meticorten', 'Orasone', 'Paracort', 'Prednicen-mPrednisone', 'Prednisone intensol', 'Rayos', 'Servisone', 'Sterapred']",... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1674 | Q6 | What genes does Bortezomib target when it's used to treat multiple myeloma? | When used to treat multiple myeloma, the drug Bortezomib targets the genes PSMD1, PSMB2, PSMB1, PSMB5, PSMB8, PSMB9, PSMB6, PSMD14, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMA7, PSMA8, PSMB10, PSMB11, PSMB3, PSMB4, PSMB7, ADRM1, PSMC2, PSMC1, PSMC4, PSMC6, PSMC3, PSMC5, PSMD2, PSMD3, PSMD12, PSMD11, PSMD6, PSMD7, PS... | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%bortezomib%" OR LOWER(tradeNames_list) LIKE "%bor... | [{'UUID': 'DrugTargetsIndication121923_text_349846', 'drugName': 'Bortezomib', 'tradeNames_list': "['Velcade']", 'syns_list': "['Bortezomib', 'Bortezomib accord', 'Bortezomib hydrate', 'LDP-341NSC-681239', 'PS-341', 'Velcade']", 'target': 'ENSG00000136930', 'approvedSymbol': 'PSMB7', 'approvedName': 'proteasome 20S sub... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1697 | Q6 | What genes does Buprenorphine target when it's used to treat substance abuse? | When used to treat substance abuse, the drug Buprenorphine targets the genes OPRM1 and OPRK1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%buprenorphine%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_764199', 'drugName': 'Buprenorphine', 'tradeNames_list': "['Bupeaze', 'Buplast', 'Butec', 'Butrans', 'Hapoctasin', 'Panitaz', 'PrenotrixReletrans', 'Sevodyne', 'Sublocade', 'Temgesic', 'Tephine', 'Transtec']", 'syns_list': "['ALKS-5461 COMPONENT BUPRENORPHINE', 'Brixadi', 'Bu... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.686 | Q6 | What genes does Pemetrexed target when it's used to treat gastric cancer? | Pemetrexed has not been approved by the FDA as a treatment for gastric cancer, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are TYMS, GART, and DHFR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%pemetrexed%" OR LOWER(tradeNames_list) LIKE "%pem... | [{'UUID': 'DrugTargetsIndication121923_text_919166', 'drugName': 'Pemetrexed', 'tradeNames_list': "['Alimta', 'Pemfexy']", 'syns_list': "['LY-2315', 'LY-231514', 'LY231514', 'NSC-698037', 'Pemetrexed']", 'target': 'ENSG00000228716', 'approvedSymbol': 'DHFR', 'approvedName': 'dihydrofolate reductase', 'mesh_heading': 'S... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1485 | Q6 | What genes does Amantadine Hydrochloride target when it's used to treat postencephalitic Parkinson disease? | When used to treat postencephalitic Parkinson disease, the drug Amantadine Hydrochloride targets the genes GRIN1, GRIN2A, GRIN2B, GRIN2D, GRIN3B, GRIN2C, and GRIN3A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%amantadine hydrochloride%" OR LOWER(tradeNames_li... | [{'UUID': 'DrugTargetsIndication121923_text_441093', 'drugName': 'Amantadine Hydrochloride', 'tradeNames_list': "['Amantadine hydrochloride', 'Gocovri', 'Lysovir', 'Mantadine', 'Osmolex erSymadine', 'Symmetrel']", 'syns_list': "['Adamantanamine hydrochloride', 'Amantadine hclAmantadine hydrochloride', 'EXP-105-1', 'Man... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1455 | Q6 | What genes does Epinephrine target when it's used to treat heart failure? | Epinephrine has not been approved by the FDA as a treatment for heart failure, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are ADRA1A, ADRB2, ADRB1, ADRB3, ADRA1D, ADRA1B, ADRA2A, ADRA2C, and ADRA2B. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%epinephrine%" OR LOWER(tradeNames_list) LIKE "%ep... | [{'UUID': 'DrugTargetsIndication121923_text_361076', 'drugName': 'Epinephrine', 'tradeNames_list': "['Adren co', 'Adrenaclick', 'Adrenalin', 'Ana-Kit', 'Ana-guard', 'AnapenAnaphylactic shock drug kit', 'Asma-vydrin', 'Asthmahaler', 'Auvi-qBronkaid mist', 'Brovon', 'Emerade', 'Epi e z pen jr', 'EpinephrineEpinephrine (c... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1486 | Q6 | What genes does Gilteritinib Fumarate target when it's used to treat acute myeloid leukemia? | When used to treat acute myeloid leukemia, the drug Gilteritinib Fumarate targets the genes FLT3 and AXL. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%gilteritinib fumarate%" OR LOWER(tradeNames_list)... | [{'UUID': 'DrugTargetsIndication121923_text_933939', 'drugName': 'Gilteritinib Fumarate', 'tradeNames_list': "['Xospata']", 'syns_list': "['ASP-2215 HEMIFUMARATE', 'ASP2215 hemifumarate', 'Gilteritinib fumarateGilteritinib hemifumarate']", 'target': 'ENSG00000167601', 'approvedSymbol': 'AXL', 'approvedName': 'AXL recep... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1292 | Q6 | What genes does Prednisone target when it's used to treat keratitis? | When used to treat keratitis, the drug Prednisone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%prednisone%" OR LOWER(tradeNames_list) LIKE "%pre... | [{'UUID': 'DrugTargetsIndication121923_text_218699', 'drugName': 'Prednisone', 'tradeNames_list': "['Cortan', 'Cortancyl', 'Decortisyl', 'Delta-dome', 'Deltasone', 'FernisoneLiquid pred', 'Lodotra', 'Meticorten', 'Orasone', 'Paracort', 'Prednicen-mPrednisone', 'Prednisone intensol', 'Rayos', 'Servisone', 'Sterapred']",... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1232 | Q6 | What genes does Phenylephrine Hydrochloride target when it's used to treat sinusitis? | When used to treat sinusitis, the drug Phenylephrine Hydrochloride targets the genes ADRA1A, ADRA1D, and ADRA1B. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%phenylephrine hydrochloride%" OR LOWER(tradeNames... | [{'UUID': 'DrugTargetsIndication121923_text_416703', 'drugName': 'Phenylephrine Hydrochloride', 'tradeNames_list': "['Afrin 4 hour nasal spray', 'Biomydrin', 'Biorphen', 'Fenilfar', 'FenoxMydfrin', 'Nazex', 'Neo-synephrine', 'Neosynephrine', 'NostrilNurofen sinus pain relief', 'Phenylephrine hydrochloride', 'PrefrinVaz... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.525 | Q6 | What genes does Enalapril Maleate target when it's used to treat congestive heart failure? | When used to treat congestive heart failure, the drug Enalapril Maleate targets the gene ACE. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%enalapril maleate%" OR LOWER(tradeNames_list) LIK... | [{'UUID': 'DrugTargetsIndication121923_text_1091899', 'drugName': 'Enalapril Maleate', 'tradeNames_list': "['Ednyt', 'Enalapril maleate', 'Enapren', 'Epaned', 'Epaned kit', 'InnovacePralenal 10', 'Pralenal 2.5', 'Pralenal 20', 'Pralenal 5', 'RenitecVasotec', 'Xanef']", 'syns_list': "['Enalapril maleate', 'MK-421', 'NSC... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
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