uuid stringlengths 4 8 | template_uuid stringclasses 40
values | question stringlengths 13 193 | answer stringlengths 29 2.2k | benchmark_query stringlengths 133 622 | execution_results stringlengths 2 1.14M | query_type stringclasses 2
values | sql_category stringclasses 26
values | bio_category stringclasses 14
values |
|---|---|---|---|---|---|---|---|---|
Q6.946 | Q6 | What genes does Vandetanib target when it's used to treat clear cell renal carcinoma? | Vandetanib has not been approved by the FDA as a treatment for clear cell renal carcinoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are EGFR, ERBB3, KDR, SRC, TEK, ERBB2, FLT1, FLT4, EPHA2, RET, ERBB4, EPHB4, PTK6, EPHB2, EPHA5, EPHA4, EPHA8, EPHA6, EPHA7,... | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%vandetanib%" OR LOWER(tradeNames_list) LIKE "%van... | [{'UUID': 'DrugTargetsIndication121923_text_210152', 'drugName': 'Vandetanib', 'tradeNames_list': "['Caprelsa', 'Zactima']", 'syns_list': "['GNF-PF-2188', 'NSC-744325', 'NSC-760766', 'Vandetanib', 'ZD-64', 'ZD-6474ZD6474']", 'target': 'ENSG00000146648', 'approvedSymbol': 'EGFR', 'approvedName': 'epidermal growth factor... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.366 | Q6 | What genes does Degarelix target when it's used to treat neoplasm? | When used to treat neoplasm, the drug Degarelix targets the gene GNRHR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%degarelix%" OR LOWER(tradeNames_list) LIKE "%dega... | [{'UUID': 'DrugTargetsIndication121923_text_1097157', 'drugName': 'Degarelix Acetate', 'tradeNames_list': "['Firmagon']", 'syns_list': "['Degarelix (as acetate)', 'Degarelix acetate', 'Degarelix acetate hydrateFE-200486', 'FE200486', 'FE200486 (FREE BASE)']", 'target': 'ENSG00000109163', 'approvedSymbol': 'GNRHR', 'app... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.540 | Q6 | What genes does Liraglutide target when it's used to treat bipolar disorder? | Liraglutide has not been approved by the FDA as a treatment for bipolar disorder, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is GLP1R. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%liraglutide%" OR LOWER(tradeNames_list) LIKE "%li... | [{'UUID': 'DrugTargetsIndication121923_text_1044530', 'drugName': 'Liraglutide', 'tradeNames_list': "['Saxenda', 'Victoza']", 'syns_list': "['Liraglutide', 'Liraglutide (rdna origin)', 'Liraglutide recombinantNN-2211', 'NN-9924', 'NN2211', 'NN9924', 'NNC 90-1170', 'NNC-90-1170']", 'target': 'ENSG00000112164', 'approved... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.79 | Q6 | What genes does Fenofibrate target when it's used to treat hypothyroidism? | When used to treat hypothyroidism, the drug Fenofibrate targets the gene PPARA. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fenofibrate%" OR LOWER(tradeNames_list) LIKE "%fe... | [{'UUID': 'DrugTargetsIndication121923_text_244086', 'drugName': 'Fenofibrate', 'tradeNames_list': "['Antara', 'Antara (micronized)', 'Fenofibrate', 'Fenofibrate (micronized)Fenogal', 'Fenoglide', 'Lipantil', 'Lipantil micro 200Lipantil micro 267', 'Lipantil micro 67', 'Lipidil', 'LipofenSupralip 160', 'Tricor', 'Trico... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1917 | Q6 | What genes does Testosterone Undecanoate target when it's used to treat hypogonadotropic hypogonadism? | When used to treat hypogonadotropic hypogonadism, the drug Testosterone Undecanoate targets the gene AR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%testosterone undecanoate%" OR LOWER(tradeNames_li... | [{'UUID': 'DrugTargetsIndication121923_text_922041', 'drugName': 'Testosterone Undecanoate', 'tradeNames_list': "['Andriol', 'Aveed', 'Jatenzo', 'Kyzatrex', 'Nebido', 'RestandolRestandol testocap', 'Tlando', 'Undestor']", 'syns_list': "['Kyzatrex', 'MK-3033', 'ORG 538', 'ORG-538', 'TSX-011Testosterone 17.beta.-undecyla... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1416 | Q6 | What genes does Ambrisentan target when it's used to treat pulmonary hypertension? | When used to treat pulmonary hypertension, the drug Ambrisentan targets the genes EDNRA and EDNRB. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ambrisentan%" OR LOWER(tradeNames_list) LIKE "%am... | [{'UUID': 'DrugTargetsIndication121923_text_1084075', 'drugName': 'Ambrisentan', 'tradeNames_list': "['Letairis', 'Volibris']", 'syns_list': "['Ambrisentan', 'GSK-1325760', 'GSK-1325760A', 'GSK1325760', 'GSK1325760ALU-208075']", 'target': 'ENSG00000151617', 'approvedSymbol': 'EDNRA', 'approvedName': 'endothelin recepto... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.586 | Q6 | What genes does Pemigatinib target when it's used to treat cholangiocarcinoma? | When used to treat cholangiocarcinoma, the drug Pemigatinib targets the genes FGFR1, FGFR3, and FGFR2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%pemigatinib%" OR LOWER(tradeNames_list) LIKE "%pe... | [{'UUID': 'DrugTargetsIndication121923_text_706925', 'drugName': 'Pemigatinib', 'tradeNames_list': "['Pemazyre']", 'syns_list': "['Fgfr inhibitor incb054828', 'INCB054828', 'Incb-054828', 'Incb054828Pemigatinib']", 'target': 'ENSG00000077782', 'approvedSymbol': 'FGFR1', 'approvedName': 'fibroblast growth factor recepto... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1795 | Q6 | What genes does Lidocaine target when it's used to treat myofascial pain syndrome? | Lidocaine has not been approved by the FDA as a treatment for myofascial pain syndrome, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lidocaine%" OR LOWER(tradeNames_list) LIKE "%lido... | [{'UUID': 'DrugTargetsIndication121923_text_638300', 'drugName': 'Lidocaine', 'tradeNames_list': "['Alphacaine', 'Anestacon', 'Dentipatch', 'Lidocaine', 'LidodermLignocaine Hcl', 'Lignostab', 'Lmx 4', 'Oraqix', 'Vagisil', 'XylocaineXylodase', 'Xylotox', 'Ztlido']", 'syns_list': "['ALGRX 3268', 'ALGRX-3268', 'Anestacon'... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.771 | Q6 | What genes does Selpercatinib target when it's used to treat cancer? | When used to treat cancer, the drug Selpercatinib targets the genes RET, CCDC6, and KIF5B. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%selpercatinib%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_944390', 'drugName': 'Selpercatinib', 'tradeNames_list': "['Retevmo']", 'syns_list': "['LOXO-292', 'LY-3527723', 'LY3527723', 'Loxo-292', 'Ret inhibitor loxo-292Selpercatinib']", 'target': 'ENSG00000165731', 'approvedSymbol': 'RET', 'approvedName': 'ret proto-oncogene', 'mesh... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.371 | Q6 | What genes does Memantine Hydrochloride target when it's used to treat central nervous system cancer? | Memantine Hydrochloride has not been approved by the FDA as a treatment for central nervous system cancer, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are GRIN1, GRIN2A, GRIN2B, GRIN2D, GRIN3B, GRIN2C, and GRIN3A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%memantine hydrochloride%" OR LOWER(tradeNames_lis... | [{'UUID': 'DrugTargetsIndication121923_text_455065', 'drugName': 'Memantine Hydrochloride', 'tradeNames_list': "['Akatinol', 'Ebixa', 'Marixino', 'Memantine', 'Memantine hydrochlorideNamenda', 'Namenda xr', 'Nemdatine', 'Valios']", 'syns_list': "['Acrescent', 'Auxura', 'Balaxur', 'FP-01', 'Memantine accord', 'Memantine... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.809 | Q6 | What genes does Velcalcetide target when it's used to treat secondary hyperparathyroidism? | When used to treat secondary hyperparathyroidism, the drug Velcalcetide targets the gene CASR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%velcalcetide%" OR LOWER(tradeNames_list) LIKE "%v... | [{'UUID': 'DrugTargetsIndication121923_text_1148962', 'drugName': 'Velcalcetide', 'tradeNames_list': "['Parsabiv']", 'syns_list': "['AMG-416', 'Amg416', 'Etelcalcetide', 'KAI-4169', 'ONO-5163', 'TelcalcetideVelcalcetide']", 'target': 'ENSG00000036828', 'approvedSymbol': 'CASR', 'approvedName': 'calcium sensing receptor... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.31 | Q6 | What genes does Naproxen target when it's used to treat gout? | When used to treat gout, the drug Naproxen targets the genes PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%naproxen%" OR LOWER(tradeNames_list) LIKE "%napro... | [{'UUID': 'DrugTargetsIndication121923_text_838134', 'drugName': 'Naproxen Sodium', 'tradeNames_list': "['Aleve', 'Anaprox', 'Anaprox ds', 'Naprelan', 'Naproxen sodium', 'Synflex']", 'syns_list': "['BAY-117031', 'BAY117031', 'BAYH6689', 'Naproxen sodiumNaproxen sodium anhydrous', 'Naproxen sodium salt', 'RS-3650']", 't... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1960 | Q6 | What genes does Lorazepam target when it's used to treat unipolar depression? | When used to treat unipolar depression, the drug Lorazepam targets the genes GABRA1, GABRB2, GABRG2, GABRB3, GABRA4, GABRG3, GABRQ, GABRA3, GABRP, GABRD, GABRG1, GABRB1, GABRE, GABRA2, GABRA5, and GABRA6. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lorazepam%" OR LOWER(tradeNames_list) LIKE "%lora... | [{'UUID': 'DrugTargetsIndication121923_text_958521', 'drugName': 'Lorazepam', 'tradeNames_list': "['Abbloraz', 'Ativan', 'Loraz', 'Lorazepam', 'Lorazepam intensolLorazepam preservative free', 'Loreev xr', 'Temesta']", 'syns_list': "['Lorazepam', 'Lorazepam civ', 'NSC-289758', 'WY-4036']", 'target': 'ENSG00000022355', '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1742 | Q6 | What genes does Risperidone target when it's used to treat bipolar I disorder? | When used to treat bipolar I disorder, the drug Risperidone targets the genes HTR2C, DRD2, and HTR2A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%risperidone%" OR LOWER(tradeNames_list) LIKE "%ri... | [{'UUID': 'DrugTargetsIndication121923_text_149657', 'drugName': 'Risperidone', 'tradeNames_list': "['Perseris kit', 'Risperdal', 'Risperdal Consta Long Acting', 'Risperdal MRisperdal M-Tab', 'Risperdal consta', 'Risperdal quicklet', 'Risperidone']", 'syns_list': "['LY-03004', 'LY03004', 'N05AX08', 'NSC-759895', 'Perse... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1577 | Q6 | What genes does Everolimus target when it's used to treat gastric cancer? | Everolimus has not been approved by the FDA as a treatment for gastric cancer, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is FKBP1A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%everolimus%" OR LOWER(tradeNames_list) LIKE "%eve... | [{'UUID': 'DrugTargetsIndication121923_text_1085620', 'drugName': 'Everolimus', 'tradeNames_list': "['Afinitor', 'Afinitor disperz', 'Certican', 'Votubia', 'Zortress']", 'syns_list': "['40-o-(2-hydroxyethyl)-rapamycin', 'Everolimus', 'RAD 666', 'RAD-001RAD-666', 'RAD001', 'SDZ-RAD', 'Sdz rad']", 'target': 'ENSG00000088... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.794 | Q6 | What genes does Famotidine target when it's used to treat ulcer disease? | When used to treat ulcer disease, the drug Famotidine targets the gene HRH2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%famotidine%" OR LOWER(tradeNames_list) LIKE "%fam... | [{'UUID': 'DrugTargetsIndication121923_text_1100340', 'drugName': 'Famotidine', 'tradeNames_list': "['Famotidine', 'Famotidine preservative freeFamotidine preservative free (pharmacy bulk)', 'Fluxid', 'PepcidPepcid ac', 'Pepcid preservative free', 'Pepcid rpd']", 'syns_list': "['Amfamox', 'Fadul', 'Famodil', 'Famosan',... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1249 | Q6 | What genes does Dexamethasone target when it's used to treat neoplasm? | When used to treat neoplasm, the drug Dexamethasone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dexamethasone%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_227461', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.501 | Q6 | What genes does Paclitaxel target when it's used to treat laryngeal squamous cell carcinoma? | Paclitaxel has not been approved by the FDA as a treatment for laryngeal squamous cell carcinoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are TUBB4B, TUBB1, TUBA3C, TUBA4A, TUBB3, TUBA1A, TUBB4A, TUBB8, TUBB, TUBA1B, TUBA1C, TUBA3E, TUBB2A, TUBB2B, and TU... | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%paclitaxel%" OR LOWER(tradeNames_list) LIKE "%pac... | [{'UUID': 'DrugTargetsIndication121923_text_826', 'drugName': 'Paclitaxel', 'tradeNames_list': "['Abraxane', 'Pacitaxel', 'Paclitaxel', 'Paxene', 'Taxol', 'Taxol 100']", 'syns_list': "['(-)-paclitaxel', 'ABI-007', 'ABI-007 COMPONENT PACLITAXEL', 'BMS 181339-01BMS-181339-01', 'Capxol', 'Cyclopax', 'DHP 107', 'DHP-107', ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1551 | Q6 | What genes does Tretinoin target when it's used to treat acute promyelocytic leukemia? | When used to treat acute promyelocytic leukemia, the drug Tretinoin targets the genes RARG, RARB, and RARA. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%tretinoin%" OR LOWER(tradeNames_list) LIKE "%tret... | [{'UUID': 'DrugTargetsIndication121923_text_1053517', 'drugName': 'Tretinoin', 'tradeNames_list': "['Acticin', 'Altreno', 'Atralin', 'Avita', 'Renova', 'Retin-a', 'Retin-a microRetin-a-micro', 'Tretin-X', 'Tretinoin', 'Vesanoid']", 'syns_list': "['Aberel', 'All-trans retinoic acid', 'All-trans-retinoic acid', 'EudynaKe... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1568 | Q6 | What genes does Ceritinib target when it's used to treat neoplasm? | When used to treat neoplasm, the drug Ceritinib targets the genes ALK, EML4, and NPM1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ceritinib%" OR LOWER(tradeNames_list) LIKE "%ceri... | [{'UUID': 'DrugTargetsIndication121923_text_991833', 'drugName': 'Ceritinib', 'tradeNames_list': "['Zykadia']", 'syns_list': "['Ceritinib', 'Ceritinib[mi]', 'LDK-378', 'LDK378', 'NVP-LDK-378-NXNVP-LDK378-NX']", 'target': 'ENSG00000171094', 'approvedSymbol': 'ALK', 'approvedName': 'ALK receptor tyrosine kinase', 'mesh_h... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.991 | Q6 | What genes does Glycopyrrolate target when it's used to treat Airway obstruction? | When used to treat Airway obstruction, the drug Glycopyrrolate targets the genes CHRM3 and CHRM1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%glycopyrrolate%" OR LOWER(tradeNames_list) LIKE "... | [{'UUID': 'DrugTargetsIndication121923_text_857534', 'drugName': 'Glycopyrrolate', 'tradeNames_list': "['Cuvposa', 'Dartisla odt', 'Glycopyrrolate', 'Glyrx-pfLonhala magnair kit', 'Robinul', 'Robinul forte', 'Robinul fte', 'SeebriSialanar']", 'syns_list': "['AD-237', 'AHR-504', 'CHF-5259', 'CHF5259', 'GlycopyrrolateGly... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1574 | Q6 | What genes does Patisiran Sodium target when it's used to treat familial amyloid neuropathy? | When used to treat familial amyloid neuropathy, the drug Patisiran Sodium targets the gene TTR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%patisiran sodium%" OR LOWER(tradeNames_list) LIKE... | [{'UUID': 'DrugTargetsIndication121923_text_1097699', 'drugName': 'Patisiran Sodium', 'tradeNames_list': "['Onpattro']", 'syns_list': "['Patisiran sodium']", 'target': 'ENSG00000118271', 'approvedSymbol': 'TTR', 'approvedName': 'transthyretin', 'mesh_heading': 'Amyloid Neuropathies, Familial', 'efo_term': 'familial amy... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.45 | Q6 | What genes does Testosterone target when it's used to treat Hereditary breast and ovarian cancer syndrome? | Testosterone has not been approved by the FDA as a treatment for Hereditary breast and ovarian cancer syndrome, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is AR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%testosterone%" OR LOWER(tradeNames_list) LIKE "%t... | [{'UUID': 'DrugTargetsIndication121923_text_922692', 'drugName': 'Testosterone', 'tradeNames_list': "['Androderm', 'Androgel', 'Androgel 1%', 'Andropatch', 'Axiron', 'FortestaIntrinsa', 'Natesto', 'Striant', 'Striant sr', 'Testim', 'Testim 1%Testoderm', 'Testoderm tts', 'Testogel', 'Testopatch', 'Testopel', 'TestoralTe... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1608 | Q6 | What genes does Cannabidiol target when it's used to treat heart failure? | Cannabidiol has not been approved by the FDA as a treatment for heart failure, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is CNR1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%cannabidiol%" OR LOWER(tradeNames_list) LIKE "%ca... | [{'UUID': 'DrugTargetsIndication121923_text_1073703', 'drugName': 'Cannabidiol', 'tradeNames_list': "['Epidiolex']", 'syns_list': "['(-)-cannabidiol', '(-)-cbd', '(-)-trans-cannabidiol.delta.1(2)-trans-cannabidiol', 'BTX-1204', 'BTX-1503', 'CBD', 'CannabidiolCannabidiol solution', 'Cardiolrx', 'GWP-42003', 'GWP-42003-P... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.171 | Q6 | What genes does Amisulpride target when it's used to treat psychosis? | When used to treat psychosis, the drug Amisulpride targets the genes HTR2C, DRD2, DRD3, HTR2A, HTR3A, HTR1A, HTR3E, HTR3B, HTR3D, HTR3C, HTR4, HTR1F, HTR2B, HTR1B, HTR1D, HTR1E, HTR7, HTR6, and HTR5A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%amisulpride%" OR LOWER(tradeNames_list) LIKE "%am... | [{'UUID': 'DrugTargetsIndication121923_text_151513', 'drugName': 'Amisulpride', 'tradeNames_list': "['Barhemsys', 'Solian', 'Solian 100', 'Solian 200', 'Solian 400', 'Solian 50']", 'syns_list': "['APD-421', 'APD421', 'Aminosultopride', 'Amisulpride', 'DAN-2163', 'DenibanNSC-760085', 'Socian', 'Sulamid']", 'target': 'EN... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.307 | Q6 | What genes does Prednisolone Acetate target when it's used to treat hemorrhoid? | When used to treat hemorrhoid, the drug Prednisolone Acetate targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%prednisolone acetate%" OR LOWER(tradeNames_list) ... | [{'UUID': 'DrugTargetsIndication121923_text_243763', 'drugName': 'Prednisolone Acetate', 'tradeNames_list': "['Econopred', 'Flo-pred', 'Meticortelone', 'Omnipred', 'Pred forte', 'Pred ftePred mild', 'Prednisolone acetate', 'Sterane', 'Ultracortenol']", 'syns_list': "['NSC-10966', 'Prednisolone 21-acetate', 'Prednisolon... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1957 | Q6 | What genes does Rivaroxaban target when it's used to treat Recurrent thrombophlebitis? | When used to treat Recurrent thrombophlebitis, the drug Rivaroxaban targets the gene F10. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%rivaroxaban%" OR LOWER(tradeNames_list) LIKE "%ri... | [{'UUID': 'DrugTargetsIndication121923_text_708854', 'drugName': 'Rivaroxaban', 'tradeNames_list': "['Xarelto']", 'syns_list': "['BAY 59-7939', 'BAY-59-7939', 'JNJ-39039039', 'JNJ39039039', 'Rivaroxaban']", 'target': 'ENSG00000126218', 'approvedSymbol': 'F10', 'approvedName': 'coagulation factor X', 'mesh_heading': 'Th... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1105 | Q6 | What genes does Axitinib target when it's used to treat neoplasm? | When used to treat neoplasm, the drug Axitinib targets the genes KDR, FLT1, and FLT4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%axitinib%" OR LOWER(tradeNames_list) LIKE "%axiti... | [{'UUID': 'DrugTargetsIndication121923_text_689869', 'drugName': 'Axitinib', 'tradeNames_list': "['Inlyta']", 'syns_list': "['AG-013736', 'AG-13736', 'Axitinib', 'NSC-757441']", 'target': 'ENSG00000037280', 'approvedSymbol': 'FLT4', 'approvedName': 'fms related receptor tyrosine kinase 4', 'mesh_heading': 'Neoplasms', ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1925 | Q6 | What genes does Ciclesonide target when it's used to treat asthma? | When used to treat asthma, the drug Ciclesonide targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ciclesonide%" OR LOWER(tradeNames_list) LIKE "%ci... | [{'UUID': 'DrugTargetsIndication121923_text_217456', 'drugName': 'Ciclesonide', 'tradeNames_list': "['Alvesco', 'Alvesco 160', 'Alvesco 80', 'Omnaris', 'Zetonna']", 'syns_list': "['BI54903', 'Ciclesonide', 'RPR-251526', 'RPR251526']", 'target': 'ENSG00000113580', 'approvedSymbol': 'NR3C1', 'approvedName': 'nuclear rece... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1038 | Q6 | What genes does Bupropion Hydrochloride target when it's used to treat major depressive disorder? | When used to treat major depressive disorder, the drug Bupropion Hydrochloride targets the genes SLC6A2 and SLC6A3. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%bupropion hydrochloride%" OR LOWER(tradeNames_lis... | [{'UUID': 'DrugTargetsIndication121923_text_434125', 'drugName': 'Bupropion Hydrochloride', 'tradeNames_list': "['Bupropion hydrochloride', 'Forfivo xl', 'Wellbutrin', 'Wellbutrin 100Wellbutrin 75', 'Wellbutrin sr', 'Wellbutrin xl', 'Zyban']", 'syns_list': "['Amfebutamone hydrochloride', 'BW 323', 'BW-323', 'BW323', 'B... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.658 | Q6 | What genes does Esketamine Hydrochloride target when it's used to treat pain? | Esketamine Hydrochloride has not been approved by the FDA as a treatment for pain, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are GRIN1, GRIN2A, GRIN2B, GRIN2D, GRIN3B, GRIN2C, and GRIN3A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%esketamine hydrochloride%" OR LOWER(tradeNames_li... | [{'UUID': 'DrugTargetsIndication121923_text_454751', 'drugName': 'Esketamine Hydrochloride', 'tradeNames_list': "['Spravato']", 'syns_list': "['AM-101', 'Esketamine hydrochloride', 'Ketamine hydrochloride, (s)-Ketamine hydrochloride, s-', 'Ketanest s']", 'target': 'ENSG00000176884', 'approvedSymbol': 'GRIN1', 'approved... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.373 | Q6 | What genes does Clozapine target when it's used to treat schizoaffective disorder? | When used to treat schizoaffective disorder, the drug Clozapine targets the genes DRD2 and HTR2A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%clozapine%" OR LOWER(tradeNames_list) LIKE "%cloz... | [{'UUID': 'DrugTargetsIndication121923_text_157985', 'drugName': 'Clozapine', 'tradeNames_list': "['Clozapine', 'Clozaril', 'Fazaclo', 'Fazaclo odt', 'Versacloz', 'Zaponex']", 'syns_list': "['Clozapine', 'Clozapine (caraco)', 'Clozapine (clozaril)Clozapine (fazaclo)', 'Clozapine (ivax)', 'Clozapine (mylan)Clozapine (te... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1661 | Q6 | What genes does Everolimus target when it's used to treat urinary bladder cancer? | Everolimus has not been approved by the FDA as a treatment for urinary bladder cancer, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is FKBP1A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%everolimus%" OR LOWER(tradeNames_list) LIKE "%eve... | [{'UUID': 'DrugTargetsIndication121923_text_1085584', 'drugName': 'Everolimus', 'tradeNames_list': "['Afinitor', 'Afinitor disperz', 'Certican', 'Votubia', 'Zortress']", 'syns_list': "['40-o-(2-hydroxyethyl)-rapamycin', 'Everolimus', 'RAD 666', 'RAD-001RAD-666', 'RAD001', 'SDZ-RAD', 'Sdz rad']", 'target': 'ENSG00000088... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1513 | Q6 | What genes does Midostaurin target when it's used to treat Mastocytosis? | When used to treat Mastocytosis, the drug Midostaurin targets the genes KDR, FLT3, KIT, PDGFRB, PDGFRA, PRKCE, PRKCB, PRKD3, PRKCI, PRKCA, PRKCG, PRKCD, PRKCZ, PRKCH, PRKD1, and PRKCQ. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%midostaurin%" OR LOWER(tradeNames_list) LIKE "%mi... | [{'UUID': 'DrugTargetsIndication121923_text_667305', 'drugName': 'Midostaurin', 'tradeNames_list': "['Rydapt']", 'syns_list': "['CGP 41251', 'CGP-41251', 'Midostaurin', 'NSC-656576', 'NVP-PKC412', 'PKC 412PKC-412', 'Pkc-412']", 'target': 'ENSG00000128052', 'approvedSymbol': 'KDR', 'approvedName': 'kinase insert domain ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.778 | Q6 | What genes does Teriflunomide target when it's used to treat immune system disease? | When used to treat immune system disease, the drug Teriflunomide targets the gene DHODH. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%teriflunomide%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_1191752', 'drugName': 'Teriflunomide', 'tradeNames_list': "['Aubagio']", 'syns_list': "['A77 1726', 'HMR-1726', 'HMR1726', 'Leflunomide related compound bLeflunomide related compound b rs', 'Teriflunomide']", 'target': 'ENSG00000102967', 'approvedSymbol': 'DHODH', 'approvedNa... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.328 | Q6 | What genes does Cobimetinib Fumarate target when it's used to treat metastatic melanoma? | When used to treat metastatic melanoma, the drug Cobimetinib Fumarate targets the genes MAP2K2 and MAP2K1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%cobimetinib fumarate%" OR LOWER(tradeNames_list) ... | [{'UUID': 'DrugTargetsIndication121923_text_927155', 'drugName': 'Cobimetinib Fumarate', 'tradeNames_list': "['Cotellic']", 'syns_list': "['Cobimetinib fumarate', 'Cobimetinib hemifumarate', 'Gdc-0973 hemifumarateXl-518 hemifumarate']", 'target': 'ENSG00000126934', 'approvedSymbol': 'MAP2K2', 'approvedName': 'mitogen-a... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1988 | Q6 | What genes does Duloxetine Hydrochloride target when it's used to treat fibromyalgia? | When used to treat fibromyalgia, the drug Duloxetine Hydrochloride targets the genes SLC6A4 and SLC6A2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%duloxetine hydrochloride%" OR LOWER(tradeNames_li... | [{'UUID': 'DrugTargetsIndication121923_text_206077', 'drugName': 'Duloxetine Hydrochloride', 'tradeNames_list': "['Ariclaim', 'Cymbalta', 'Drizalma sprinkle', 'DuciltiaDuloxetine hydrochloride', 'Yentreve']", 'syns_list': "['Ariclaim', 'Duloxetine (as hydrochloride)', 'Duloxetine hclDuloxetine hydrochloride', 'Duloxeti... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1924 | Q6 | What genes does Aspirin target when it's used to treat arthritis? | When used to treat arthritis, the drug Aspirin targets the genes PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%aspirin%" OR LOWER(tradeNames_list) LIKE "%aspiri... | [{'UUID': 'DrugTargetsIndication121923_text_833964', 'drugName': 'Aspirin', 'tradeNames_list': "['8-hour bayer', 'Acetosalic Acid', 'Acetylsalic acidAcetylsalicylic Acid', 'Alka rapid', 'Anadin all night', 'Angettes 75Aspirin', 'Aspro clr', 'Bayer extra strength aspirin for migraine painDanamep', 'Disprin cv', 'Disprin... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.931 | Q6 | What genes does Eltrombopag Olamine target when it's used to treat chronic hepatitis C virus infection? | When used to treat chronic hepatitis C virus infection, the drug Eltrombopag Olamine targets the gene MPL. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%eltrombopag olamine%" OR LOWER(tradeNames_list) L... | [{'UUID': 'DrugTargetsIndication121923_text_1055973', 'drugName': 'Eltrombopag Olamine', 'tradeNames_list': "['Promacta', 'Promacta kit']", 'syns_list': "['Eltrombopag (as olamine)', 'Eltrombopag compd with 2-aminoethanol (1:2)Eltrombopag olamine', 'SB-497115-GR']", 'target': 'ENSG00000117400', 'approvedSymbol': 'MPL',... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.188 | Q6 | What genes does Cyclosporine target when it's used to treat allergic conjunctivitis? | Cyclosporine has not been approved by the FDA as a treatment for allergic conjunctivitis, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is PPIA. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%cyclosporine%" OR LOWER(tradeNames_list) LIKE "%c... | [{'UUID': 'DrugTargetsIndication121923_text_1101256', 'drugName': 'Cyclosporine', 'tradeNames_list': "['Capimune', 'Capsorin', 'Cequa', 'Cyclosporine', 'Deximune', 'GengrafIkervis', 'Neoral', 'Optimmune', 'Restasis', 'Restasis multidoseSandimmun', 'Sandimmune', 'Sangcya', 'Vanquoral', 'Verkazia']", 'syns_list': "['27-4... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1595 | Q6 | What genes does Dimethyl Fumarate target when it's used to treat obstructive sleep apnea? | Dimethyl Fumarate has not been approved by the FDA as a treatment for obstructive sleep apnea, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is KEAP1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dimethyl fumarate%" OR LOWER(tradeNames_list) LIK... | [{'UUID': 'DrugTargetsIndication121923_text_1055750', 'drugName': 'Dimethyl Fumarate', 'tradeNames_list': "['Tecfidera']", 'syns_list': "['AZL 0 211089', 'AZL O 211089', 'AZL-0211089', 'AZL-O-211089', 'BG 00012BG 12', 'BG-00012', 'BG-12', 'BG00012', 'Dimethyl fumar', 'Dimethyl fumarateFAG-201', 'FP-187', 'FP187', 'Fuma... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.772 | Q6 | What genes does Spironolactone target when it's used to treat heart failure? | When used to treat heart failure, the drug Spironolactone targets the gene NR3C2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%spironolactone%" OR LOWER(tradeNames_list) LIKE "... | [{'UUID': 'DrugTargetsIndication121923_text_1094582', 'drugName': 'Spironolactone', 'tradeNames_list': "['Abbolactone', 'Aldactone', 'Carospir', 'Diatensec', 'Gx spironolLaractone', 'Spiretic', 'Spiroctan 100', 'Spiroctan 25', 'Spiroctan 50Spironolactone', 'Spirospare 100', 'Spirospare 25']", 'syns_list': "['NSC-150399... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1203 | Q6 | What genes does Testosterone Cypionate target when it's used to treat neoplasm? | When used to treat neoplasm, the drug Testosterone Cypionate targets the gene AR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%testosterone cypionate%" OR LOWER(tradeNames_list... | [{'UUID': 'DrugTargetsIndication121923_text_921013', 'drugName': 'Testosterone Cypionate', 'tradeNames_list': "['Andro-Cyp', 'Depandro', 'Depo-testosterone', 'Depotest', 'TestosteroneTestosterone cypionate']", 'syns_list': "['Depo-Testadiol', 'NSC-9157Testosterone 17.beta.-cyclopentanepropionate', 'Testosterone cipiona... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.500 | Q6 | What genes does Propranolol Hydrochloride target when it's used to treat hypertension? | When used to treat hypertension, the drug Propranolol Hydrochloride targets the genes ADRB2 and ADRB1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%propranolol hydrochloride%" OR LOWER(tradeNames_l... | [{'UUID': 'DrugTargetsIndication121923_text_937040', 'drugName': 'Propranolol Hydrochloride', 'tradeNames_list': "['Angilol', 'Apsolol', 'Avlocardyl', 'Bedranol', 'Bedranol s.r.', 'BerkololBeta-prograne mr', 'Betadur cr', 'Cardinol', 'DupromexHalf beta-prograne mr', 'Half propanix la', 'Half propatard laHalf-beprane cr... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1064 | Q6 | What genes does Nitroglycerin target when it's used to treat hemorrhoid? | When used to treat hemorrhoid, the drug Nitroglycerin targets the genes GUCY1B1, GUCY1B2, GUCY1A2, and GUCY1A1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%nitroglycerin%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_972652', 'drugName': 'Nitroglycerin', 'tradeNames_list': "['Coro-nitro', 'Deponit 10', 'Deponit 5', 'Glytrin', 'Gonitro', 'Lenitral 7.5Minitran', 'Minitran 10', 'Minitran 15', 'Minitran 5', 'NatiroseNitriderm tts', 'Nitro iv', 'Nitro-bid', 'Nitro-dur', 'Nitro-mack retNitrocin... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1111 | Q6 | What genes does Dexamethasone target when it's used to treat infection? | When used to treat infection, the drug Dexamethasone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dexamethasone%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_230313', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.536 | Q6 | What genes does Esketamine Hydrochloride target when it's used to treat Tinnitus? | Esketamine Hydrochloride has not been approved by the FDA as a treatment for Tinnitus, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are GRIN1, GRIN2A, GRIN2B, GRIN2D, GRIN3B, GRIN2C, and GRIN3A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%esketamine hydrochloride%" OR LOWER(tradeNames_li... | [{'UUID': 'DrugTargetsIndication121923_text_454752', 'drugName': 'Esketamine Hydrochloride', 'tradeNames_list': "['Spravato']", 'syns_list': "['AM-101', 'Esketamine hydrochloride', 'Ketamine hydrochloride, (s)-Ketamine hydrochloride, s-', 'Ketanest s']", 'target': 'ENSG00000176884', 'approvedSymbol': 'GRIN1', 'approved... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1601 | Q6 | What genes does Prednisone target when it's used to treat nephrotic syndrome? | When used to treat nephrotic syndrome, the drug Prednisone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%prednisone%" OR LOWER(tradeNames_list) LIKE "%pre... | [{'UUID': 'DrugTargetsIndication121923_text_218683', 'drugName': 'Prednisone', 'tradeNames_list': "['Cortan', 'Cortancyl', 'Decortisyl', 'Delta-dome', 'Deltasone', 'FernisoneLiquid pred', 'Lodotra', 'Meticorten', 'Orasone', 'Paracort', 'Prednicen-mPrednisone', 'Prednisone intensol', 'Rayos', 'Servisone', 'Sterapred']",... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.752 | Q6 | What genes does Argatroban target when it's used to treat thrombotic disease? | When used to treat thrombotic disease, the drug Argatroban targets the gene F2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%argatroban%" OR LOWER(tradeNames_list) LIKE "%arg... | [{'UUID': 'DrugTargetsIndication121923_text_1093397', 'drugName': 'Argatroban', 'tradeNames_list': "['Acova', 'Argatroban', 'Argatroban in dextroseArgatroban in sodium chloride']", 'syns_list': "['Argatroban', 'Argatroban anhydrous', 'Argatroban hydrateArgatroban monohydrate', 'Argipidine', 'DK-7419', 'GN-1600', 'GN160... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1933 | Q6 | What genes does Celecoxib target when it's used to treat spondylitis? | When used to treat spondylitis, the drug Celecoxib targets the gene PTGS2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%celecoxib%" OR LOWER(tradeNames_list) LIKE "%cele... | [{'UUID': 'DrugTargetsIndication121923_text_833170', 'drugName': 'Celecoxib', 'tradeNames_list': "['Celebra', 'Celebrex', 'Celecoxib', 'Elyxyb', 'Onsenal']", 'syns_list': "['Celecoxib', 'DFN-15', 'DFN15', 'NSC-719627', 'NSC-758624', 'SC-58635']", 'target': 'ENSG00000073756', 'approvedSymbol': 'PTGS2', 'approvedName': '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1367 | Q6 | What genes does Fludarabine Phosphate target when it's used to treat nasopharyngeal neoplasm? | Fludarabine Phosphate has not been approved by the FDA as a treatment for nasopharyngeal neoplasm, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are POLA1, POLD4, POLD3, POLD1, POLD2, POLE, POLA2, PRIM1, PRIM2, POLE2, POLE3, RRM1, RRM2B, and RRM2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fludarabine phosphate%" OR LOWER(tradeNames_list)... | [{'UUID': 'DrugTargetsIndication121923_text_754521', 'drugName': 'Fludarabine Phosphate', 'tradeNames_list': "['Fludara', 'Fludarabine phosphate', 'Oforta']", 'syns_list': '[\'2-f-ara-amp\', \'2-f-araa\', \'2-fluoro ara-a\', \'2-fluorovidarabineFludarabine\', "Fludarabine 5\'-monophosphateFludarabine monophosphateFluda... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1444 | Q6 | What genes does Ciclesonide target when it's used to treat Nasal congestion? | When used to treat Nasal congestion, the drug Ciclesonide targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ciclesonide%" OR LOWER(tradeNames_list) LIKE "%ci... | [{'UUID': 'DrugTargetsIndication121923_text_217451', 'drugName': 'Ciclesonide', 'tradeNames_list': "['Alvesco', 'Alvesco 160', 'Alvesco 80', 'Omnaris', 'Zetonna']", 'syns_list': "['BI54903', 'Ciclesonide', 'RPR-251526', 'RPR251526']", 'target': 'ENSG00000113580', 'approvedSymbol': 'NR3C1', 'approvedName': 'nuclear rece... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.178 | Q6 | What genes does Alendronate Sodium target when it's used to treat postmenopausal osteoporosis? | When used to treat postmenopausal osteoporosis, the drug Alendronate Sodium targets the gene FDPS. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%alendronate sodium%" OR LOWER(tradeNames_list) LI... | [{'UUID': 'DrugTargetsIndication121923_text_1099490', 'drugName': 'Alendronate Sodium', 'tradeNames_list': "['Alendronate sodium', 'Binosto', 'Fosamax']", 'syns_list': "['Adrovance', 'Alendronate (as sodium)', 'Alendronate sodiumAlendronate sodium hydrate', 'Alendronate sodium trihydrateAlendronic acid monosodium salt ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.470 | Q6 | What genes does Topotecan Hydrochloride target when it's used to treat ovarian cancer? | When used to treat ovarian cancer, the drug Topotecan Hydrochloride targets the gene TOP1MT. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%topotecan hydrochloride%" OR LOWER(tradeNames_lis... | [{'UUID': 'DrugTargetsIndication121923_text_1193578', 'drugName': 'Topotecan Hydrochloride', 'tradeNames_list': "['Hycamptin', 'Hycamtin', 'Topotecan', 'Topotecan hydrochloride']", 'syns_list': "['Evotopin', 'NSC-759263', 'Nogitecan hydrochloride', 'SK&F S-104864-ASK&F-S-104864A', 'SK-S-104864-A', 'Topotecan (as hydroc... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1337 | Q6 | What genes does Everolimus target when it's used to treat Kidney Angiomyolipoma? | When used to treat Kidney Angiomyolipoma, the drug Everolimus targets the gene FKBP1A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%everolimus%" OR LOWER(tradeNames_list) LIKE "%eve... | [{'UUID': 'DrugTargetsIndication121923_text_1085639', 'drugName': 'Everolimus', 'tradeNames_list': "['Afinitor', 'Afinitor disperz', 'Certican', 'Votubia', 'Zortress']", 'syns_list': "['40-o-(2-hydroxyethyl)-rapamycin', 'Everolimus', 'RAD 666', 'RAD-001RAD-666', 'RAD001', 'SDZ-RAD', 'Sdz rad']", 'target': 'ENSG00000088... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1611 | Q6 | What genes does Mifepristone target when it's used to treat Cushing syndrome? | When used to treat Cushing syndrome, the drug Mifepristone targets the genes NR3C1 and PGR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%mifepristone%" OR LOWER(tradeNames_list) LIKE "%m... | [{'UUID': 'DrugTargetsIndication121923_text_242473', 'drugName': 'Mifepristone', 'tradeNames_list': "['Korlym', 'Mifegyne', 'Mifeprex']", 'syns_list': "['Mifepristone', 'NSC-759862', 'RU 38486', 'RU 486', 'RU-38486', 'RU-486RU486']", 'target': 'ENSG00000113580', 'approvedSymbol': 'NR3C1', 'approvedName': 'nuclear recep... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.126 | Q6 | What genes does Albuterol target when it's used to treat pulmonary edema? | Albuterol has not been approved by the FDA as a treatment for pulmonary edema, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is ADRB2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%albuterol%" OR LOWER(tradeNames_list) LIKE "%albu... | [{'UUID': 'DrugTargetsIndication121923_text_936750', 'drugName': 'Albuterol', 'tradeNames_list': "['Aerolin', 'Aerolin 400', 'Aerolin auto', 'Airomir', 'Airsalb', 'AlbuterolAsmasal clickhaler', 'Asmasal spacehaler', 'Asmaven', 'AsmaventCobutolin', 'Combivent', 'Combivent udvs', 'Ipramol steri-neb', 'KentamolLibetist', ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.355 | Q6 | What genes does Epinephrine target when it's used to treat Mydriasis? | When used to treat Mydriasis, the drug Epinephrine targets the genes ADRA1A, ADRB2, ADRB1, ADRB3, ADRA1D, ADRA1B, ADRA2A, ADRA2C, and ADRA2B. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%epinephrine%" OR LOWER(tradeNames_list) LIKE "%ep... | [{'UUID': 'DrugTargetsIndication121923_text_361086', 'drugName': 'Epinephrine', 'tradeNames_list': "['Adren co', 'Adrenaclick', 'Adrenalin', 'Ana-Kit', 'Ana-guard', 'AnapenAnaphylactic shock drug kit', 'Asma-vydrin', 'Asthmahaler', 'Auvi-qBronkaid mist', 'Brovon', 'Emerade', 'Epi e z pen jr', 'EpinephrineEpinephrine (c... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.388 | Q6 | What genes does Duvelisib target when it's used to treat lymphoma? | When used to treat lymphoma, the drug Duvelisib targets the genes PIK3CD and PIK3CG. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%duvelisib%" OR LOWER(tradeNames_list) LIKE "%duve... | [{'UUID': 'DrugTargetsIndication121923_text_858820', 'drugName': 'Duvelisib', 'tradeNames_list': "['Copiktra']", 'syns_list': "['Duvelisib', 'Duvelisib hydrate', 'Duvelisib monohydrate', 'INK-1147INK-1197', 'IPI-145']", 'target': 'ENSG00000171608', 'approvedSymbol': 'PIK3CD', 'approvedName': 'phosphatidylinositol-4,5-b... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1435 | Q6 | What genes does Cyclosporine target when it's used to treat eye disease? | When used to treat eye disease, the drug Cyclosporine targets the gene PPIA. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%cyclosporine%" OR LOWER(tradeNames_list) LIKE "%c... | [{'UUID': 'DrugTargetsIndication121923_text_1101283', 'drugName': 'Cyclosporine', 'tradeNames_list': "['Capimune', 'Capsorin', 'Cequa', 'Cyclosporine', 'Deximune', 'GengrafIkervis', 'Neoral', 'Optimmune', 'Restasis', 'Restasis multidoseSandimmun', 'Sandimmune', 'Sangcya', 'Vanquoral', 'Verkazia']", 'syns_list': "['27-4... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1007 | Q6 | What genes does Imatinib Mesylate target when it's used to treat male breast carcinoma? | Imatinib Mesylate has not been approved by the FDA as a treatment for male breast carcinoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are ABL1, BCR, KIT, and PDGFRB. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%imatinib mesylate%" OR LOWER(tradeNames_list) LIK... | [{'UUID': 'DrugTargetsIndication121923_text_743501', 'drugName': 'Imatinib Mesylate', 'tradeNames_list': "['Gleevec', 'Glivec', 'Imatinib mesylate']", 'syns_list': "['Gleevec', 'Imatinib (as mesilate)', 'Imatinib accord', 'Imatinib medacImatinib mesilate', 'Imatinib mesylate', 'Imatinib methane sulfonateImatinib methan... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.894 | Q6 | What genes does Telmisartan target when it's used to treat hypertension? | When used to treat hypertension, the drug Telmisartan targets the gene AGTR1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%telmisartan%" OR LOWER(tradeNames_list) LIKE "%te... | [{'UUID': 'DrugTargetsIndication121923_text_1072710', 'drugName': 'Telmisartan', 'tradeNames_list': "['Micardis', 'Telmisartan', 'Tolura']", 'syns_list': "['BIBR 277 SE', 'BIBR-277', 'BIBR-277 SE', 'BIBR-277-SE', 'BIBR-277SEC09CA07', 'Kinzalmono', 'Pritor', 'Semintra', 'TelmisartanTelmisartan actavis', 'Telmisartan tev... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1495 | Q6 | What genes does Bromocriptine Mesylate target when it's used to treat hyperprolactinemia? | When used to treat hyperprolactinemia, the drug Bromocriptine Mesylate targets the genes DRD2, DRD3, and DRD4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%bromocriptine mesylate%" OR LOWER(tradeNames_list... | [{'UUID': 'DrugTargetsIndication121923_text_201375', 'drugName': 'Bromocriptine Mesylate', 'tradeNames_list': "['Bromocriptine mesylate', 'Cycloset', 'Parlodel']", 'syns_list': "['2-bromoergocryptine mesylate', 'Bromocriptine mesilateBromocriptine mesylate', 'Bromocriptine methanesulfonate', 'CB-154CB-154 MESYLATE', 'C... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.335 | Q6 | What genes does Aspirin target when it's used to treat Fever? | When used to treat Fever, the drug Aspirin targets the genes PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%aspirin%" OR LOWER(tradeNames_list) LIKE "%aspiri... | [{'UUID': 'DrugTargetsIndication121923_text_834424', 'drugName': 'Aspirin', 'tradeNames_list': "['8-hour bayer', 'Acetosalic Acid', 'Acetylsalic acidAcetylsalicylic Acid', 'Alka rapid', 'Anadin all night', 'Angettes 75Aspirin', 'Aspro clr', 'Bayer extra strength aspirin for migraine painDanamep', 'Disprin cv', 'Disprin... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.975 | Q6 | What genes does Methylphenidate target when it's used to treat delirium? | Methylphenidate has not been approved by the FDA as a treatment for delirium, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are SLC6A2 and SLC6A3. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%methylphenidate%" OR LOWER(tradeNames_list) LIKE ... | [{'UUID': 'DrugTargetsIndication121923_text_439359', 'drugName': 'Methylphenidate', 'tradeNames_list': "['Concerta', 'Cotempla xr-odt', 'Daytrana']", 'syns_list': "['Concerta', 'Methylin', 'MethylphenidateMethylphenidate extended release', 'Prc-063', 'Threo-dl-methylphenidate']", 'target': 'ENSG00000103546', 'approvedS... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.197 | Q6 | What genes does Dexamethasone target when it's used to treat multiple sclerosis? | When used to treat multiple sclerosis, the drug Dexamethasone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dexamethasone%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_230370', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.520 | Q6 | What genes does Vandetanib target when it's used to treat thyroid carcinoma? | When used to treat thyroid carcinoma, the drug Vandetanib targets the genes EGFR, ERBB3, KDR, SRC, TEK, ERBB2, FLT1, FLT4, EPHA2, RET, ERBB4, EPHB4, PTK6, EPHB2, EPHA5, EPHA4, EPHA8, EPHA6, EPHA7, EPHB3, EPHA3, EPHB1, EPHA1, EPHB6, and EPHA10. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%vandetanib%" OR LOWER(tradeNames_list) LIKE "%van... | [{'UUID': 'DrugTargetsIndication121923_text_212009', 'drugName': 'Vandetanib', 'tradeNames_list': "['Caprelsa', 'Zactima']", 'syns_list': "['GNF-PF-2188', 'NSC-744325', 'NSC-760766', 'Vandetanib', 'ZD-64', 'ZD-6474ZD6474']", 'target': 'ENSG00000037280', 'approvedSymbol': 'FLT4', 'approvedName': 'fms related receptor ty... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.459 | Q6 | What genes does Cannabidiol target when it's used to treat toothache? | Cannabidiol has not been approved by the FDA as a treatment for toothache, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is CNR1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%cannabidiol%" OR LOWER(tradeNames_list) LIKE "%ca... | [{'UUID': 'DrugTargetsIndication121923_text_1073706', 'drugName': 'Cannabidiol', 'tradeNames_list': "['Epidiolex']", 'syns_list': "['(-)-cannabidiol', '(-)-cbd', '(-)-trans-cannabidiol.delta.1(2)-trans-cannabidiol', 'BTX-1204', 'BTX-1503', 'CBD', 'CannabidiolCannabidiol solution', 'Cardiolrx', 'GWP-42003', 'GWP-42003-P... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1714 | Q6 | What genes does Ponesimod target when it's used to treat immune system disease? | When used to treat immune system disease, the drug Ponesimod targets the gene S1PR1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ponesimod%" OR LOWER(tradeNames_list) LIKE "%pone... | [{'UUID': 'DrugTargetsIndication121923_text_1036650', 'drugName': 'Ponesimod', 'tradeNames_list': "['Ponvory']", 'syns_list': "['ACT-128800', 'Ponesimod']", 'target': 'ENSG00000170989', 'approvedSymbol': 'S1PR1', 'approvedName': 'sphingosine-1-phosphate receptor 1', 'mesh_heading': 'Immune System Diseases', 'efo_term':... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.326 | Q6 | What genes does Celecoxib target when it's used to treat osteoarthritis? | When used to treat osteoarthritis, the drug Celecoxib targets the gene PTGS2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%celecoxib%" OR LOWER(tradeNames_list) LIKE "%cele... | [{'UUID': 'DrugTargetsIndication121923_text_833505', 'drugName': 'Celecoxib', 'tradeNames_list': "['Celebra', 'Celebrex', 'Celecoxib', 'Elyxyb', 'Onsenal']", 'syns_list': "['Celecoxib', 'DFN-15', 'DFN15', 'NSC-719627', 'NSC-758624', 'SC-58635']", 'target': 'ENSG00000073756', 'approvedSymbol': 'PTGS2', 'approvedName': '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1323 | Q6 | What genes does Methotrexate target when it's used to treat bone marrow failure syndrome? | Methotrexate has not been approved by the FDA as a treatment for bone marrow failure syndrome, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is DHFR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%methotrexate%" OR LOWER(tradeNames_list) LIKE "%m... | [{'UUID': 'DrugTargetsIndication121923_text_1057487', 'drugName': 'Methotrexate', 'tradeNames_list': "['Amethopterin', 'Ebetrex', 'Emtexate high-pot', 'Emtexate pf', 'FolexMaxtrex', 'Methotrexate', 'Metoject', 'Mexate', 'Otrexup', 'Otrexup pfsRasuvo', 'Reditrex', 'Rheumatrex', 'Trexall', 'Zlatal']", 'syns_list': "['(r)... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.269 | Q6 | What genes does Betamethasone Dipropionate target when it's used to treat hemorrhoid? | When used to treat hemorrhoid, the drug Betamethasone Dipropionate targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%betamethasone dipropionate%" OR LOWER(tradeNames_... | [{'UUID': 'DrugTargetsIndication121923_text_220896', 'drugName': 'Betamethasone Dipropionate', 'tradeNames_list': "['Alphatrex', 'Betamethasone dipropionate', 'Diprolene', 'Diprolene afDiprosone', 'Sernivo']", 'syns_list': "['Betamethasone (as dipropionate)', 'Betamethasone 17,21-dipropionateBetamethasone dipropionate'... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.799 | Q6 | What genes does Ivosidenib target when it's used to treat cancer? | When used to treat cancer, the drug Ivosidenib targets the gene IDH1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ivosidenib%" OR LOWER(tradeNames_list) LIKE "%ivo... | [{'UUID': 'DrugTargetsIndication121923_text_924605', 'drugName': 'Ivosidenib', 'tradeNames_list': "['Tibsovo']", 'syns_list': "['AG-120', 'Ivosidenib']", 'target': 'ENSG00000138413', 'approvedSymbol': 'IDH1', 'approvedName': 'isocitrate dehydrogenase (NADP(+)) 1', 'mesh_heading': 'Neoplasms', 'efo_term': 'cancer', 'yea... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1432 | Q6 | What genes does Beclomethasone Dipropionate target when it's used to treat Airway obstruction? | When used to treat Airway obstruction, the drug Beclomethasone Dipropionate targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%beclomethasone dipropionate%" OR LOWER(tradeNames... | [{'UUID': 'DrugTargetsIndication121923_text_221042', 'drugName': 'Beclomethasone Dipropionate', 'tradeNames_list': "['Aerobec 100', 'Aerobec 50', 'Aerobec fte 250', 'Asmabec clickhalerAsmabec spacehaler', 'Beclazone 100', 'Beclazone 100 e-breatheBeclazone 200', 'Beclazone 250', 'Beclazone 250 e-breathe', 'Beclazone 50B... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.70 | Q6 | What genes does Dabrafenib Mesylate target when it's used to treat metastatic melanoma? | When used to treat metastatic melanoma, the drug Dabrafenib Mesylate targets the gene BRAF. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dabrafenib mesylate%" OR LOWER(tradeNames_list) L... | [{'UUID': 'DrugTargetsIndication121923_text_752713', 'drugName': 'Dabrafenib Mesylate', 'tradeNames_list': "['Tafinlar']", 'syns_list': "['Dabrafenib mesilate', 'Dabrafenib mesylateGSK-2118436 METHANESULFONATE SALT', 'GSK-2118436BGSK-2118436B MESYLATE', 'GSK-2118436B METHANESULFONATE SALTGSK2118436B', 'GSK2118436B, MET... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.938 | Q6 | What genes does Tepotinib Hydrochloride target when it's used to treat non-small cell lung carcinoma? | When used to treat non-small cell lung carcinoma, the drug Tepotinib Hydrochloride targets the gene MET. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%tepotinib hydrochloride%" OR LOWER(tradeNames_lis... | [{'UUID': 'DrugTargetsIndication121923_text_936138', 'drugName': 'Tepotinib Hydrochloride', 'tradeNames_list': "['Tepmetko']", 'syns_list': "['MSC2156119J', 'Msc2156119j', 'Tepotinib hydrochlorideTepotinib hydrochloride hydrate']", 'target': 'ENSG00000105976', 'approvedSymbol': 'MET', 'approvedName': 'MET proto-oncogen... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1447 | Q6 | What genes does Testosterone Enanthate target when it's used to treat hypogonadism? | When used to treat hypogonadism, the drug Testosterone Enanthate targets the gene AR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%testosterone enanthate%" OR LOWER(tradeNames_list... | [{'UUID': 'DrugTargetsIndication121923_text_921384', 'drugName': 'Testosterone Enanthate', 'tradeNames_list': "['Delatestryl', 'Primoteston depot', 'Testosterone enanthateXyosted (autoinjector)']", 'syns_list': "['Androtardyl', 'NSC-17591', 'Testosterone enantateTestosterone enanthate', 'Testosterone enanthate ciiiTest... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1782 | Q6 | What genes does Ponatinib Hydrochloride target when it's used to treat acute myeloid leukemia? | Ponatinib Hydrochloride has not been approved by the FDA as a treatment for acute myeloid leukemia, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are ABL1 and BCR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ponatinib hydrochloride%" OR LOWER(tradeNames_lis... | [{'UUID': 'DrugTargetsIndication121923_text_749492', 'drugName': 'Ponatinib Hydrochloride', 'tradeNames_list': "['Iclusig']", 'syns_list': "['AP-24534 HCL', 'AP24534 HCL', 'Ponatinib hydrochloride']", 'target': 'ENSG00000097007', 'approvedSymbol': 'ABL1', 'approvedName': 'ABL proto-oncogene 1, non-receptor tyrosine kin... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.468 | Q6 | What genes does Gabapentin Enacarbil target when it's used to treat neuralgia? | When used to treat neuralgia, the drug Gabapentin Enacarbil targets the genes CACNA1B, CACNA1C, CACNA1S, CACNA1D, CACNA1F, CACNA2D2, CACNA2D1, CACNA1H, CACNA1G, CACNA1I, CACNA1A, CACNA2D3, CACNA2D4, CACNA1E, CACNB4, CACNB2, CACNB1, CACNB3, CACNG7, CACNG5, CACNG2, CACNG4, CACNG8, CACNG3, CACNG6, and CACNG1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%gabapentin enacarbil%" OR LOWER(tradeNames_list) ... | [{'UUID': 'DrugTargetsIndication121923_text_891811', 'drugName': 'Gabapentin Enacarbil', 'tradeNames_list': "['Horizant']", 'syns_list': "['ASP-8825', 'ASP8825', 'GSK1838262', 'Gabapentin enacarbilGabapentin encarbil', 'Gsk-1838262', 'XP 13512', 'XP-13512', 'XP13512']", 'target': 'ENSG00000148408', 'approvedSymbol': 'C... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1396 | Q6 | What genes does Gemcitabine Hydrochloride target when it's used to treat liver cancer? | Gemcitabine Hydrochloride has not been approved by the FDA as a treatment for liver cancer, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are POLA1, POLD4, POLD3, POLD1, POLD2, POLE, POLA2, PRIM1, PRIM2, POLE2, POLE3, RRM1, RRM2B, and RRM2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%gemcitabine hydrochloride%" OR LOWER(tradeNames_l... | [{'UUID': 'DrugTargetsIndication121923_text_756051', 'drugName': 'Gemcitabine Hydrochloride', 'tradeNames_list': "['Gemcitabine hydrochloride', 'Gemzar', 'Infugem']", 'syns_list': "['Gemcitabine (as hydrochloride)', 'Gemcitabine hclGemcitabine hydrochloride', 'Gemzar', 'LY-188011LY-188011 HYDROCHLORIDE', 'LY188011 HYDR... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1614 | Q6 | What genes does Lamotrigine target when it's used to treat epilepsy with generalized tonic-clonic seizures? | When used to treat epilepsy with generalized tonic-clonic seizures, the drug Lamotrigine targets the genes SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lamotrigine%" OR LOWER(tradeNames_list) LIKE "%la... | [{'UUID': 'DrugTargetsIndication121923_text_653154', 'drugName': 'Lamotrigine', 'tradeNames_list': "['Lamictal', 'Lamictal cd', 'Lamictal odt', 'Lamictal xr', 'Lamotrigine']", 'syns_list': "['BW 430C', 'BW-430C', 'Lamotrigine', 'NSC-759171']", 'target': 'ENSG00000144285', 'approvedSymbol': 'SCN1A', 'approvedName': 'sod... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.549 | Q6 | What genes does Sirolimus target when it's used to treat Thalassemia? | Sirolimus has not been approved by the FDA as a treatment for Thalassemia, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is FKBP1A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%sirolimus%" OR LOWER(tradeNames_list) LIKE "%siro... | [{'UUID': 'DrugTargetsIndication121923_text_1084789', 'drugName': 'Sirolimus', 'tradeNames_list': "['Fyarro', 'Hyftor', 'Rapamune', 'Sirolimus']", 'syns_list': "['AY-22989', 'Fyarro', 'Hyftor', 'L04AA10', 'NSC-226080', 'Npc-12g', 'RapalimusRapamycin', 'SM-88 COMPONENT SIROLIMUS', 'Sirolimus', 'WY-090217']", 'target': '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.538 | Q6 | What genes does Angiotensin Ii Acetate target when it's used to treat septic shock? | When used to treat septic shock, the drug Angiotensin Ii Acetate targets the gene AGTR1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%angiotensin ii acetate%" OR LOWER(tradeNames_list... | [{'UUID': 'DrugTargetsIndication121923_text_1072628', 'drugName': 'Angiotensin Ii Acetate', 'tradeNames_list': "['Giapreza']", 'syns_list': "['Angiotensin ii acetate', 'Angiotensin ii acetate humanAngiotensin ii triacetate', 'Human angiotensin ii acetate salt']", 'target': 'ENSG00000144891', 'approvedSymbol': 'AGTR1', ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1230 | Q6 | What genes does Mirabegron target when it's used to treat Urinary incontinence? | When used to treat Urinary incontinence, the drug Mirabegron targets the gene ADRB3. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%mirabegron%" OR LOWER(tradeNames_list) LIKE "%mir... | [{'UUID': 'DrugTargetsIndication121923_text_937726', 'drugName': 'Mirabegron', 'tradeNames_list': "['Betmiga', 'Myrbetriq', 'Myrbetriq granules']", 'syns_list': "['Betanis', 'Mirabegron', 'YM-178', 'YM178']", 'target': 'ENSG00000188778', 'approvedSymbol': 'ADRB3', 'approvedName': 'adrenoceptor beta 3', 'mesh_heading': ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.957 | Q6 | What genes does Sirolimus target when it's used to treat rectum cancer? | Sirolimus has not been approved by the FDA as a treatment for rectum cancer, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is FKBP1A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%sirolimus%" OR LOWER(tradeNames_list) LIKE "%siro... | [{'UUID': 'DrugTargetsIndication121923_text_1084452', 'drugName': 'Sirolimus', 'tradeNames_list': "['Fyarro', 'Hyftor', 'Rapamune', 'Sirolimus']", 'syns_list': "['AY-22989', 'Fyarro', 'Hyftor', 'L04AA10', 'NSC-226080', 'Npc-12g', 'RapalimusRapamycin', 'SM-88 COMPONENT SIROLIMUS', 'Sirolimus', 'WY-090217']", 'target': '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1635 | Q6 | What genes does Fludarabine Phosphate target when it's used to treat severe combined immunodeficiency? | Fludarabine Phosphate has not been approved by the FDA as a treatment for severe combined immunodeficiency, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are POLA1, POLD4, POLD3, POLD1, POLD2, POLE, POLA2, PRIM1, PRIM2, POLE2, POLE3, RRM1, RRM2B, and RRM2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fludarabine phosphate%" OR LOWER(tradeNames_list)... | [{'UUID': 'DrugTargetsIndication121923_text_754594', 'drugName': 'Fludarabine Phosphate', 'tradeNames_list': "['Fludara', 'Fludarabine phosphate', 'Oforta']", 'syns_list': '[\'2-f-ara-amp\', \'2-f-araa\', \'2-fluoro ara-a\', \'2-fluorovidarabineFludarabine\', "Fludarabine 5\'-monophosphateFludarabine monophosphateFluda... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1418 | Q6 | What genes does Capsaicin target when it's used to treat osteoarthritis? | When used to treat osteoarthritis, the drug Capsaicin targets the gene TRPV1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%capsaicin%" OR LOWER(tradeNames_list) LIKE "%caps... | [{'UUID': 'DrugTargetsIndication121923_text_993158', 'drugName': 'Capsaicin', 'tradeNames_list': "['Qutenza', 'Zacin', 'Zostrix', 'Zostrix hp']", 'syns_list': "['ALGRX 4975', 'ALGRX-4975', 'Ausanil', 'Axsain', 'Capsaicin', 'Capzasin-hpCntx-4975', 'Dolenon', 'FEMA NO. 3404', 'Mioton', 'NGX-1998', 'NGX-4010NSC-56353', 'N... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.422 | Q6 | What genes does Naloxone Hydrochloride target when it's used to treat pain? | When used to treat pain, the drug Naloxone Hydrochloride targets the genes OPRM1, OPRK1, and OPRD1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%naloxone hydrochloride%" OR LOWER(tradeNames_list... | [{'UUID': 'DrugTargetsIndication121923_text_789394', 'drugName': 'Naloxone Hydrochloride', 'tradeNames_list': "['Evzio', 'Evzio (autoinjector)', 'Kloxxado', 'Nalone', 'NaloxoneNaloxone hydrochloride', 'Naloxone hydrochloride (autoinjector)', 'NarcanNarcan neonatal', 'Narconil', 'Prenoxad', 'Zimhi']", 'syns_list': "['An... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1935 | Q6 | What genes does Ambrisentan target when it's used to treat idiopathic and/or familial pulmonary arterial hypertension? | When used to treat idiopathic and/or familial pulmonary arterial hypertension, the drug Ambrisentan targets the genes EDNRA and EDNRB. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ambrisentan%" OR LOWER(tradeNames_list) LIKE "%am... | [{'UUID': 'DrugTargetsIndication121923_text_1084111', 'drugName': 'Ambrisentan', 'tradeNames_list': "['Letairis', 'Volibris']", 'syns_list': "['Ambrisentan', 'GSK-1325760', 'GSK-1325760A', 'GSK1325760', 'GSK1325760ALU-208075']", 'target': 'ENSG00000151617', 'approvedSymbol': 'EDNRA', 'approvedName': 'endothelin recepto... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1532 | Q6 | What genes does Vandetanib target when it's used to treat thyroid neoplasm? | When used to treat thyroid neoplasm, the drug Vandetanib targets the genes EGFR, ERBB3, KDR, SRC, TEK, ERBB2, FLT1, FLT4, EPHA2, RET, ERBB4, EPHB4, PTK6, EPHB2, EPHA5, EPHA4, EPHA8, EPHA6, EPHA7, EPHB3, EPHA3, EPHB1, EPHA1, EPHB6, and EPHA10. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%vandetanib%" OR LOWER(tradeNames_list) LIKE "%van... | [{'UUID': 'DrugTargetsIndication121923_text_209994', 'drugName': 'Vandetanib', 'tradeNames_list': "['Caprelsa', 'Zactima']", 'syns_list': "['GNF-PF-2188', 'NSC-744325', 'NSC-760766', 'Vandetanib', 'ZD-64', 'ZD-6474ZD6474']", 'target': 'ENSG00000146648', 'approvedSymbol': 'EGFR', 'approvedName': 'epidermal growth factor... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1580 | Q6 | What genes does Ponatinib target when it's used to treat non-small cell lung carcinoma? | Ponatinib has not been approved by the FDA as a treatment for non-small cell lung carcinoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are ABL1 and BCR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ponatinib%" OR LOWER(tradeNames_list) LIKE "%pona... | [{'UUID': 'DrugTargetsIndication121923_text_750223', 'drugName': 'Ponatinib', 'tradeNames_list': "['Iclusig']", 'syns_list': "['AP-24534', 'AP24534', 'Ponatinib']", 'target': 'ENSG00000097007', 'approvedSymbol': 'ABL1', 'approvedName': 'ABL proto-oncogene 1, non-receptor tyrosine kinase', 'mesh_heading': 'Carcinoma, No... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1659 | Q6 | What genes does Mometasone Furoate target when it's used to treat Nasal Cavity Polyp? | When used to treat Nasal Cavity Polyp, the drug Mometasone Furoate targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%mometasone furoate%" OR LOWER(tradeNames_list) LI... | [{'UUID': 'DrugTargetsIndication121923_text_242043', 'drugName': 'Mometasone Furoate', 'tradeNames_list': "['Asmanex', 'Asmanex hfa', 'Asmanex twisthaler', 'EloconMometasone furoate', 'Nasonex', 'Nasonex 24hr allergy', 'Sinuva']", 'syns_list': "['LAS-41002', 'LAS41002', 'LYR-210', 'LYR210', 'Lyr-210', 'MometasoneMometa... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1116 | Q6 | What genes does Siponimod Fumarate target when it's used to treat chronic progressive multiple sclerosis? | When used to treat chronic progressive multiple sclerosis, the drug Siponimod Fumarate targets the gene S1PR1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%siponimod fumarate%" OR LOWER(tradeNames_list) LI... | [{'UUID': 'DrugTargetsIndication121923_text_1036799', 'drugName': 'Siponimod Fumarate', 'tradeNames_list': "['Mayzent']", 'syns_list': "['NVP-BAF312-AEA', 'Siponimod fumarate', 'Siponimod fumaric acidSiponimod hemifumarate', 'Siponimod hemifumaric acid']", 'target': 'ENSG00000170989', 'approvedSymbol': 'S1PR1', 'approv... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.722 | Q6 | What genes does Carfilzomib target when it's used to treat Hodgkins lymphoma? | Carfilzomib has not been approved by the FDA as a treatment for Hodgkins lymphoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are PSMD1, PSMB2, PSMB1, PSMB5, PSMB8, PSMB9, PSMB6, PSMD14, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMA7, PSMA8, PSMB10, PSMB11,... | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%carfilzomib%" OR LOWER(tradeNames_list) LIKE "%ca... | [{'UUID': 'DrugTargetsIndication121923_text_267939', 'drugName': 'Carfilzomib', 'tradeNames_list': "['Kyprolis']", 'syns_list': "['Carfilzomib', 'NSC-758252', 'PR-171']", 'target': 'ENSG00000173692', 'approvedSymbol': 'PSMD1', 'approvedName': 'proteasome 26S subunit, non-ATPase 1', 'mesh_heading': 'Lymphoma, Non-Hodgki... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1247 | Q6 | What genes does Hydrocortisone target when it's used to treat Nasal congestion? | When used to treat Nasal congestion, the drug Hydrocortisone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%hydrocortisone%" OR LOWER(tradeNames_list) LIKE "... | [{'UUID': 'DrugTargetsIndication121923_text_241219', 'drugName': 'Hydrocortisone', 'tradeNames_list': "['Acetasol hc', 'Acticort', 'Aeroseb-hc', 'Ala-cort', 'Ala-scalpAlkindi sprinkle', 'Alphaderm', 'Anflam', 'Anucort-Hc', 'Anugesic hcAnusol hc', 'Anusol plus hc', 'Anusol soothing relief', 'Anusol-HcBalneol-hc', 'Beta-... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1236 | Q6 | What genes does Indomethacin target when it's used to treat eye inflammation? | When used to treat eye inflammation, the drug Indomethacin targets the genes PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%indomethacin%" OR LOWER(tradeNames_list) LIKE "%i... | [{'UUID': 'DrugTargetsIndication121923_text_828375', 'drugName': 'Indomethacin', 'tradeNames_list': "['Artracin', 'Artracin sr', 'Berlind 75 ret', 'Flexin-25 continusFlexin-50 continus', 'Flexin-75 continus', 'Imbrilon', 'Indo-lemmonIndo-paed', 'Indocid ret', 'Indocid-r', 'Indocin', 'Indocin sr', 'IndodermIndoflex', 'I... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1076 | Q6 | What genes does Lidocaine target when it's used to treat muscle cramp? | When used to treat muscle cramp, the drug Lidocaine targets the genes SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lidocaine%" OR LOWER(tradeNames_list) LIKE "%lido... | [{'UUID': 'DrugTargetsIndication121923_text_638023', 'drugName': 'Lidocaine', 'tradeNames_list': "['Alphacaine', 'Anestacon', 'Dentipatch', 'Lidocaine', 'LidodermLignocaine Hcl', 'Lignostab', 'Lmx 4', 'Oraqix', 'Vagisil', 'XylocaineXylodase', 'Xylotox', 'Ztlido']", 'syns_list': "['ALGRX 3268', 'ALGRX-3268', 'Anestacon'... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1907 | Q6 | What genes does Omeprazole target when it's used to treat cysticercosis? | Omeprazole has not been approved by the FDA as a treatment for cysticercosis, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are ATP4A and ATP4B. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%omeprazole%" OR LOWER(tradeNames_list) LIKE "%ome... | [{'UUID': 'DrugTargetsIndication121923_text_1098305', 'drugName': 'Omeprazole', 'tradeNames_list': "['Antra', 'Losec', 'Losec mups', 'Mezzopram', 'Mopral', 'Omeprazole', 'OmeranPrilosec', 'Zanprol']", 'syns_list': "['H 168/68', 'H-168/68', 'NSC-751450', 'NSC-759192', 'Omeprazole']", 'target': 'ENSG00000186009', 'approv... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.264 | Q6 | What genes does Sorafenib target when it's used to treat kidney neoplasm? | Sorafenib has not been approved by the FDA as a treatment for kidney neoplasm, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are KDR, BRAF, FLT1, FLT3, KIT, FLT4, PDGFRB, RAF1, and RET. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%sorafenib%" OR LOWER(tradeNames_list) LIKE "%sora... | [{'UUID': 'DrugTargetsIndication121923_text_683534', 'drugName': 'Sorafenib Tosylate', 'tradeNames_list': "['Nexavar']", 'syns_list': "['BAY 54-9085', 'BAY-54-9085', 'Sorafenib tosilate', 'Sorafenib tosylate']", 'target': 'ENSG00000157764', 'approvedSymbol': 'BRAF', 'approvedName': 'B-Raf proto-oncogene, serine/threoni... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1437 | Q6 | What genes does Binimetinib target when it's used to treat metastatic melanoma? | When used to treat metastatic melanoma, the drug Binimetinib targets the genes MAP2K2 and MAP2K1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%binimetinib%" OR LOWER(tradeNames_list) LIKE "%bi... | [{'UUID': 'DrugTargetsIndication121923_text_926785', 'drugName': 'Binimetinib', 'tradeNames_list': "['Mektovi']", 'syns_list': "['ARRY 438162', 'ARRY-162', 'ARRY-438162', 'Binimetinib', 'MEK-162', 'MEK162Mek-162', 'NVP-MEK162']", 'target': 'ENSG00000126934', 'approvedSymbol': 'MAP2K2', 'approvedName': 'mitogen-activate... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.