uuid stringlengths 4 8 | template_uuid stringclasses 40
values | question stringlengths 13 193 | answer stringlengths 29 2.2k | benchmark_query stringlengths 133 622 | execution_results stringlengths 2 1.14M | query_type stringclasses 2
values | sql_category stringclasses 26
values | bio_category stringclasses 14
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|---|---|---|---|---|---|---|---|---|
Q6.1654 | Q6 | What genes does Beclomethasone Dipropionate target when it's used to treat eosinophilic esophagitis? | Beclomethasone Dipropionate has not been approved by the FDA as a treatment for eosinophilic esophagitis, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%beclomethasone dipropionate%" OR LOWER(tradeNames... | [{'UUID': 'DrugTargetsIndication121923_text_221026', 'drugName': 'Beclomethasone Dipropionate', 'tradeNames_list': "['Aerobec 100', 'Aerobec 50', 'Aerobec fte 250', 'Asmabec clickhalerAsmabec spacehaler', 'Beclazone 100', 'Beclazone 100 e-breatheBeclazone 200', 'Beclazone 250', 'Beclazone 250 e-breathe', 'Beclazone 50B... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.908 | Q6 | What genes does Azilsartan Kamedoxomil target when it's used to treat hypertension? | When used to treat hypertension, the drug Azilsartan Kamedoxomil targets the gene AGTR1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%azilsartan kamedoxomil%" OR LOWER(tradeNames_list... | [{'UUID': 'DrugTargetsIndication121923_text_1072675', 'drugName': 'Azilsartan Kamedoxomil', 'tradeNames_list': "['Edarbi']", 'syns_list': "['Azilsartan kamedoxomil', 'Azilsartan medoxomil potassium', 'TAK-491']", 'target': 'ENSG00000144891', 'approvedSymbol': 'AGTR1', 'approvedName': 'angiotensin II receptor type 1', '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1904 | Q6 | What genes does Dexamethasone target when it's used to treat psoriatic arthritis? | When used to treat psoriatic arthritis, the drug Dexamethasone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dexamethasone%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_227759', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1242 | Q6 | What genes does Gabapentin Enacarbil target when it's used to treat restless legs syndrome? | When used to treat restless legs syndrome, the drug Gabapentin Enacarbil targets the genes CACNA1B, CACNA1C, CACNA1S, CACNA1D, CACNA1F, CACNA2D2, CACNA2D1, CACNA1H, CACNA1G, CACNA1I, CACNA1A, CACNA2D3, CACNA2D4, CACNA1E, CACNB4, CACNB2, CACNB1, CACNB3, CACNG7, CACNG5, CACNG2, CACNG4, CACNG8, CACNG3, CACNG6, and CACNG1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%gabapentin enacarbil%" OR LOWER(tradeNames_list) ... | [{'UUID': 'DrugTargetsIndication121923_text_891810', 'drugName': 'Gabapentin Enacarbil', 'tradeNames_list': "['Horizant']", 'syns_list': "['ASP-8825', 'ASP8825', 'GSK1838262', 'Gabapentin enacarbilGabapentin encarbil', 'Gsk-1838262', 'XP 13512', 'XP-13512', 'XP13512']", 'target': 'ENSG00000148408', 'approvedSymbol': 'C... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.24 | Q6 | What genes does Colchicine target when it's used to treat gout? | When used to treat gout, the drug Colchicine targets the genes TUBB4B, TUBB1, TUBA3C, TUBA4A, TUBB3, TUBA1A, TUBB4A, TUBB8, TUBB, TUBA1B, TUBA1C, TUBA3E, TUBB2A, TUBB2B, and TUBB6. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%colchicine%" OR LOWER(tradeNames_list) LIKE "%col... | [{'UUID': 'DrugTargetsIndication121923_text_70247', 'drugName': 'Colchicine', 'tradeNames_list': "['Colchicine', 'Colcrys', 'Gloperba', 'Mitigare']", 'syns_list': "['(-)-colchicine', 'Colchcine', 'Colchicine', 'Colchicinum', 'ColchineosColchisol', 'NSC-757']", 'target': 'ENSG00000188229', 'approvedSymbol': 'TUBB4B', 'a... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.779 | Q6 | What genes does Midostaurin target when it's used to treat mast-cell leukemia? | When used to treat mast-cell leukemia, the drug Midostaurin targets the genes KDR, FLT3, KIT, PDGFRB, PDGFRA, PRKCE, PRKCB, PRKD3, PRKCI, PRKCA, PRKCG, PRKCD, PRKCZ, PRKCH, PRKD1, and PRKCQ. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%midostaurin%" OR LOWER(tradeNames_list) LIKE "%mi... | [{'UUID': 'DrugTargetsIndication121923_text_667336', 'drugName': 'Midostaurin', 'tradeNames_list': "['Rydapt']", 'syns_list': "['CGP 41251', 'CGP-41251', 'Midostaurin', 'NSC-656576', 'NVP-PKC412', 'PKC 412PKC-412', 'Pkc-412']", 'target': 'ENSG00000122025', 'approvedSymbol': 'FLT3', 'approvedName': 'fms related receptor... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.65 | Q6 | What genes does Vasopressin target when it's used to treat acute lung injury? | Vasopressin has not been approved by the FDA as a treatment for acute lung injury, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are AVPR2, AVPR1A, and AVPR1B. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%vasopressin%" OR LOWER(tradeNames_list) LIKE "%va... | [{'UUID': 'DrugTargetsIndication121923_text_692595', 'drugName': 'Vasopressin', 'tradeNames_list': "['Beta-Hypophamine', 'Leiormone', 'Pitressin', 'Vasophysin', 'Vasostrict']", 'syns_list': "['Arginine Vasopressin', 'Arginine vasopressin', 'Argipressin or lypressinVasopressin', 'Vasopressin injection', 'Vasopressin, un... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1366 | Q6 | What genes does Bosentan target when it's used to treat pulmonary hypertension? | When used to treat pulmonary hypertension, the drug Bosentan targets the genes EDNRA and EDNRB. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%bosentan%" OR LOWER(tradeNames_list) LIKE "%bosen... | [{'UUID': 'DrugTargetsIndication121923_text_1084266', 'drugName': 'Bosentan', 'tradeNames_list': "['Tracleer']", 'syns_list': "['Anhydrous bosentan', 'Bosentan', 'Bosentan anhydrous', 'Bosentan hydrateBosentan monohydrate', 'RO 47-0203/029', 'RO-47-0203-029', 'RO-470203029']", 'target': 'ENSG00000136160', 'approvedSymb... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.191 | Q6 | What genes does Talazoparib Tosylate target when it's used to treat breast carcinoma? | When used to treat breast carcinoma, the drug Talazoparib Tosylate targets the genes PARP2 and PARP1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%talazoparib tosylate%" OR LOWER(tradeNames_list) ... | [{'UUID': 'DrugTargetsIndication121923_text_794751', 'drugName': 'Talazoparib Tosylate', 'tradeNames_list': "['Talzenna']", 'syns_list': "['BMN 673ts', 'BMN-673TS', 'Talazoparib tosilate', 'Talazoparib tosylate']", 'target': 'ENSG00000129484', 'approvedSymbol': 'PARP2', 'approvedName': 'poly(ADP-ribose) polymerase 2', ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1630 | Q6 | What genes does Levothyroxine Sodium target when it's used to treat pain? | Levothyroxine Sodium has not been approved by the FDA as a treatment for pain, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are THRA and THRB. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%levothyroxine sodium%" OR LOWER(tradeNames_list) ... | [{'UUID': 'DrugTargetsIndication121923_text_924831', 'drugName': 'Levothyroxine Sodium', 'tradeNames_list': "['Eltroxin', 'Ermeza', 'Euthyrox', 'Evotrox', 'L-thyroxine henning', 'Levo-tLevolet', 'Levothroid', 'Levothyroid', 'Levothyroxine sodium', 'LevoxineLevoxyl', 'Novothyrox', 'Soloxine', 'Synthroid', 'Thyquidity', ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1395 | Q6 | What genes does Azacitidine target when it's used to treat diffuse large B-cell lymphoma? | Azacitidine has not been approved by the FDA as a treatment for diffuse large B-cell lymphoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are DNMT1 and DNMT3A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%azacitidine%" OR LOWER(tradeNames_list) LIKE "%az... | [{'UUID': 'DrugTargetsIndication121923_text_1191973', 'drugName': 'Azacitidine', 'tradeNames_list': "['Azacitidine', 'Onureg', 'Vidaza']", 'syns_list': "['5-azacitidine', 'Azacitidine', 'Ladakamycin', 'NSC-102816', 'U-18,496U-18496', 'Vidaza']", 'target': 'ENSG00000130816', 'approvedSymbol': 'DNMT1', 'approvedName': 'D... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1547 | Q6 | What genes does Lonafarnib target when it's used to treat progeria? | When used to treat progeria, the drug Lonafarnib targets the genes FNTA and FNTB. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lonafarnib%" OR LOWER(tradeNames_list) LIKE "%lon... | [{'UUID': 'DrugTargetsIndication121923_text_148947', 'drugName': 'Lonafarnib', 'tradeNames_list': "['Zokinvy']", 'syns_list': "['Lonafarnib', 'SCH 66336', 'SCH-66336', 'SCH66336', 'Sarasar']", 'target': 'ENSG00000168522', 'approvedSymbol': 'FNTA', 'approvedName': 'farnesyltransferase, CAAX box, alpha', 'mesh_heading': ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.346 | Q6 | What genes does Aspirin target when it's used to treat brain aneurysm? | Aspirin has not been approved by the FDA as a treatment for brain aneurysm, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%aspirin%" OR LOWER(tradeNames_list) LIKE "%aspiri... | [{'UUID': 'DrugTargetsIndication121923_text_834377', 'drugName': 'Aspirin', 'tradeNames_list': "['8-hour bayer', 'Acetosalic Acid', 'Acetylsalic acidAcetylsalicylic Acid', 'Alka rapid', 'Anadin all night', 'Angettes 75Aspirin', 'Aspro clr', 'Bayer extra strength aspirin for migraine painDanamep', 'Disprin cv', 'Disprin... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.400 | Q6 | What genes does Brigatinib target when it's used to treat neoplasm? | When used to treat neoplasm, the drug Brigatinib targets the genes EGFR and ALK. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%brigatinib%" OR LOWER(tradeNames_list) LIKE "%bri... | [{'UUID': 'DrugTargetsIndication121923_text_207119', 'drugName': 'Brigatinib', 'tradeNames_list': "['Alunbrig']", 'syns_list': "['AP-26113', 'AP26113', 'Ap-26113', 'Brigatinib']", 'target': 'ENSG00000146648', 'approvedSymbol': 'EGFR', 'approvedName': 'epidermal growth factor receptor', 'mesh_heading': 'Neoplasms', 'efo... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1393 | Q6 | What genes does Lesinurad target when it's used to treat gout? | When used to treat gout, the drug Lesinurad targets the gene SLC22A12. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lesinurad%" OR LOWER(tradeNames_list) LIKE "%lesi... | [{'UUID': 'DrugTargetsIndication121923_text_1096802', 'drugName': 'Lesinurad', 'tradeNames_list': "['Zurampic']", 'syns_list': "['Lesinurad', 'RDEA 594', 'RDEA-594', 'RDEA594']", 'target': 'ENSG00000197891', 'approvedSymbol': 'SLC22A12', 'approvedName': 'solute carrier family 22 member 12', 'mesh_heading': 'Gout', 'efo... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1876 | Q6 | What genes does Latanoprost target when it's used to treat open-angle glaucoma? | When used to treat open-angle glaucoma, the drug Latanoprost targets the gene PTGFR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%latanoprost%" OR LOWER(tradeNames_list) LIKE "%la... | [{'UUID': 'DrugTargetsIndication121923_text_1149124', 'drugName': 'Latanoprost', 'tradeNames_list': "['Latanoprost', 'Monopost', 'Xalatan', 'Xelpros']", 'syns_list': "['Latanoprost', 'Latanoprost (isopropyl ester)', 'PHXA-41', 'PHXA41', 'T-2345T2345', 'XA-41', 'XA41']", 'target': 'ENSG00000122420', 'approvedSymbol': 'P... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.199 | Q6 | What genes does Modafinil target when it's used to treat attention deficit hyperactivity disorder? | When used to treat attention deficit hyperactivity disorder, the drug Modafinil targets the gene SLC6A3. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%modafinil%" OR LOWER(tradeNames_list) LIKE "%moda... | [{'UUID': 'DrugTargetsIndication121923_text_939099', 'drugName': 'Armodafinil', 'tradeNames_list': "['Armodafinil', 'Nuvigil']", 'syns_list': "['Armodafinil', 'CEP-10952', 'CEP-10953', 'CRL-40982', 'Modafinil, (r)-NSC-751850', 'NSC-758711', 'R-(-)-modafinil']", 'target': 'ENSG00000142319', 'approvedSymbol': 'SLC6A3', '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1173 | Q6 | What genes does Topiramate target when it's used to treat schizophrenia? | Topiramate has not been approved by the FDA as a treatment for schizophrenia, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, SCN10A, CA2, CA4, GABRA1, GABRB2, GABRG2, GABRB3, GABRA4, GABRG3, GAB... | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%topiramate%" OR LOWER(tradeNames_list) LIKE "%top... | [{'UUID': 'DrugTargetsIndication121923_text_457457', 'drugName': 'Topiramate', 'tradeNames_list': "['Epitomax', 'Eprontia', 'Qudexy xr', 'Topamax', 'Topamax sprinkleTopiramate', 'Trokendi xr']", 'syns_list': "['(-)-topiramate', 'Epitoma', 'Eprontia', 'MCN-4853', 'Qudexy', 'RWJ-17021RWJ-17021-000', 'Sincronil', 'Topamac... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.320 | Q6 | What genes does Pralatrexate target when it's used to treat ovarian cancer? | Pralatrexate has not been approved by the FDA as a treatment for ovarian cancer, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is DHFR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%pralatrexate%" OR LOWER(tradeNames_list) LIKE "%p... | [{'UUID': 'DrugTargetsIndication121923_text_1072525', 'drugName': 'Pralatrexate', 'tradeNames_list': "['Folotyn']", 'syns_list': "['NSC-754230', 'PDX', 'Pralatrexate']", 'target': 'ENSG00000228716', 'approvedSymbol': 'DHFR', 'approvedName': 'dihydrofolate reductase', 'mesh_heading': 'Ovarian Neoplasms', 'efo_term': 'ov... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1002 | Q6 | What genes does Defibrotide Sodium target when it's used to treat hepatic veno-occlusive disease? | When used to treat hepatic veno-occlusive disease, the drug Defibrotide Sodium targets the gene PLG. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%defibrotide sodium%" OR LOWER(tradeNames_list) LI... | [{'UUID': 'DrugTargetsIndication121923_text_993273', 'drugName': 'Defibrotide Sodium', 'tradeNames_list': "['Defitelio']", 'syns_list': "['Defibrotide sodium', 'JZP-381']", 'target': 'ENSG00000122194', 'approvedSymbol': 'PLG', 'approvedName': 'plasminogen', 'mesh_heading': 'Hepatic Veno-Occlusive Disease', 'efo_term': ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.223 | Q6 | What genes does Ibrutinib target when it's used to treat neoplasm? | When used to treat neoplasm, the drug Ibrutinib targets the gene BTK. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ibrutinib%" OR LOWER(tradeNames_list) LIKE "%ibru... | [{'UUID': 'DrugTargetsIndication121923_text_996322', 'drugName': 'Ibrutinib', 'tradeNames_list': "['Imbruvica']", 'syns_list': "['CRA-032765', 'Ibrutinib', 'PC-32765', 'PCI 32765', 'PCI-32765PCI-32765-00']", 'target': 'ENSG00000010671', 'approvedSymbol': 'BTK', 'approvedName': 'Bruton tyrosine kinase', 'mesh_heading': ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1220 | Q6 | What genes does Lisdexamfetamine Dimesylate target when it's used to treat binge eating? | When used to treat binge eating, the drug Lisdexamfetamine Dimesylate targets the genes SLC6A2, SLC18A2, and SLC6A3. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lisdexamfetamine dimesylate%" OR LOWER(tradeNames... | [{'UUID': 'DrugTargetsIndication121923_text_419194', 'drugName': 'Lisdexamfetamine Dimesylate', 'tradeNames_list': "['Elvanse', 'Elvanse adult', 'Vyvanse']", 'syns_list': "['Lisdexamfetamine dimesilate', 'Lisdexamfetamine dimesylateLisdexamfetamine dimethanesulfonate', 'Lisdexamfetamine mesilateLisdexamphetamine dimesi... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.103 | Q6 | What genes does Desmopressin Acetate target when it's used to treat enuresis? | When used to treat enuresis, the drug Desmopressin Acetate targets the genes AVPR2, AVPR1A, and AVPR1B. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%desmopressin acetate%" OR LOWER(tradeNames_list) ... | [{'UUID': 'DrugTargetsIndication121923_text_694455', 'drugName': 'Desmopressin Acetate', 'tradeNames_list': "['Concentraid', 'Ddavp', 'Ddavp (needs no refrigeration)', 'DesmomeltDesmopressin acetate', 'Desmopressin acetate (needs no refrigeration)Desmopressin acetate preservative free', 'Desmospray', 'DesmotabsMinirin'... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1655 | Q6 | What genes does Dexamethasone target when it's used to treat pulmonary tuberculosis? | When used to treat pulmonary tuberculosis, the drug Dexamethasone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dexamethasone%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_227784', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.949 | Q6 | What genes does Calcipotriene target when it's used to treat psoriasis vulgaris? | When used to treat psoriasis vulgaris, the drug Calcipotriene targets the gene VDR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%calcipotriene%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_823602', 'drugName': 'Calcipotriene', 'tradeNames_list': "['Calcipotriene', 'Dovobet', 'Dovonex', 'Enstilar', 'Sorilux', 'Xamiol']", 'syns_list': "['Calcipotriene', 'Calcipotriene hydrate', 'Calcipotriene monohydrateCalcipotriol', 'Calcipotriol anhydrous', 'Calcipotriol hydra... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1939 | Q6 | What genes does Enasidenib Mesylate target when it's used to treat acute myeloid leukemia? | When used to treat acute myeloid leukemia, the drug Enasidenib Mesylate targets the gene IDH2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%enasidenib mesylate%" OR LOWER(tradeNames_list) L... | [{'UUID': 'DrugTargetsIndication121923_text_1192245', 'drugName': 'Enasidenib Mesylate', 'tradeNames_list': "['Idhifa']", 'syns_list': "['AG-221 mesylate', 'CC-90007', 'Enasidenib mesilate', 'Enasidenib mesylateEnasidenib methanesulfonate']", 'target': 'ENSG00000182054', 'approvedSymbol': 'IDH2', 'approvedName': 'isoci... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1914 | Q6 | What genes does Omeprazole target when it's used to treat anemia (phenotype)? | Omeprazole has not been approved by the FDA as a treatment for anemia (phenotype), but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are ATP4A and ATP4B. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%omeprazole%" OR LOWER(tradeNames_list) LIKE "%ome... | [{'UUID': 'DrugTargetsIndication121923_text_1098272', 'drugName': 'Omeprazole', 'tradeNames_list': "['Antra', 'Losec', 'Losec mups', 'Mezzopram', 'Mopral', 'Omeprazole', 'OmeranPrilosec', 'Zanprol']", 'syns_list': "['H 168/68', 'H-168/68', 'NSC-751450', 'NSC-759192', 'Omeprazole']", 'target': 'ENSG00000186009', 'approv... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1127 | Q6 | What genes does Pimavanserin Tartrate target when it's used to treat psychosis? | When used to treat psychosis, the drug Pimavanserin Tartrate targets the gene HTR2A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%pimavanserin tartrate%" OR LOWER(tradeNames_list)... | [{'UUID': 'DrugTargetsIndication121923_text_205117', 'drugName': 'Pimavanserin Tartrate', 'tradeNames_list': "['Nuplazid']", 'syns_list': "['ACP-103', 'Pimavanserin tartrate']", 'target': 'ENSG00000102468', 'approvedSymbol': 'HTR2A', 'approvedName': '5-hydroxytryptamine receptor 2A', 'mesh_heading': 'Psychotic Disorder... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1052 | Q6 | What genes does Tolvaptan target when it's used to treat heart failure? | When used to treat heart failure, the drug Tolvaptan targets the gene AVPR2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%tolvaptan%" OR LOWER(tradeNames_list) LIKE "%tolv... | [{'UUID': 'DrugTargetsIndication121923_text_695126', 'drugName': 'Tolvaptan', 'tradeNames_list': "['Jinarc', 'Jynarque', 'Samsca']", 'syns_list': "['OPC-41061', 'OPC-41061(TOLVAPTAN)', 'Tolvaptan']", 'target': 'ENSG00000126895', 'approvedSymbol': 'AVPR2', 'approvedName': 'arginine vasopressin receptor 2', 'mesh_heading... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1538 | Q6 | What genes does Prednisone target when it's used to treat synovitis? | When used to treat synovitis, the drug Prednisone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%prednisone%" OR LOWER(tradeNames_list) LIKE "%pre... | [{'UUID': 'DrugTargetsIndication121923_text_218091', 'drugName': 'Prednisone', 'tradeNames_list': "['Cortan', 'Cortancyl', 'Decortisyl', 'Delta-dome', 'Deltasone', 'FernisoneLiquid pred', 'Lodotra', 'Meticorten', 'Orasone', 'Paracort', 'Prednicen-mPrednisone', 'Prednisone intensol', 'Rayos', 'Servisone', 'Sterapred']",... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.356 | Q6 | What genes does Acalabrutinib target when it's used to treat cancer? | When used to treat cancer, the drug Acalabrutinib targets the gene BTK. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%acalabrutinib%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_994368', 'drugName': 'Acalabrutinib', 'tradeNames_list': "['Calquence']", 'syns_list': "['ACP-196', 'Acalabrutinib', 'Acp-196']", 'target': 'ENSG00000010671', 'approvedSymbol': 'BTK', 'approvedName': 'Bruton tyrosine kinase', 'mesh_heading': 'Neoplasms', 'efo_term': 'cancer',... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.603 | Q6 | What genes does Ponesimod target when it's used to treat multiple sclerosis? | When used to treat multiple sclerosis, the drug Ponesimod targets the gene S1PR1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ponesimod%" OR LOWER(tradeNames_list) LIKE "%pone... | [{'UUID': 'DrugTargetsIndication121923_text_1036651', 'drugName': 'Ponesimod', 'tradeNames_list': "['Ponvory']", 'syns_list': "['ACT-128800', 'Ponesimod']", 'target': 'ENSG00000170989', 'approvedSymbol': 'S1PR1', 'approvedName': 'sphingosine-1-phosphate receptor 1', 'mesh_heading': 'Multiple Sclerosis', 'efo_term': 'mu... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1559 | Q6 | What genes does Nilotinib Hydrochloride Monohydrate target when it's used to treat Parkinson disease? | Nilotinib Hydrochloride Monohydrate has not been approved by the FDA as a treatment for Parkinson disease, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are ABL1 and BCR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%nilotinib hydrochloride monohydrate%" OR LOWER(tr... | [{'UUID': 'DrugTargetsIndication121923_text_745305', 'drugName': 'Nilotinib Hydrochloride Monohydrate', 'tradeNames_list': "['Tasigna']", 'syns_list': "['Nilotinib (as hydrochloride)', 'Nilotinib Hydrochloride MonohydrateNilotinib hydrochloride', 'Nilotinib hydrochloride anhydrousNilotinib hydrochloride hydrate', 'Nilo... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1350 | Q6 | What genes does Tafamidis Meglumine target when it's used to treat AL amyloidosis? | When used to treat AL amyloidosis, the drug Tafamidis Meglumine targets the gene TTR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%tafamidis meglumine%" OR LOWER(tradeNames_list) L... | [{'UUID': 'DrugTargetsIndication121923_text_1097631', 'drugName': 'Tafamidis Meglumine', 'tradeNames_list': "['Vyndaqel']", 'syns_list': "['FX-1006A', 'Tafamidis meglumine']", 'target': 'ENSG00000118271', 'approvedSymbol': 'TTR', 'approvedName': 'transthyretin', 'mesh_heading': 'Amyloidosis, Familial', 'efo_term': 'AL ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1359 | Q6 | What genes does Erlosamide target when it's used to treat epilepsy? | When used to treat epilepsy, the drug Erlosamide targets the genes SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%erlosamide%" OR LOWER(tradeNames_list) LIKE "%erl... | [{'UUID': 'DrugTargetsIndication121923_text_646292', 'drugName': 'Erlosamide', 'tradeNames_list': "['Lacosamide', 'Vimpat']", 'syns_list': "['(r)-lacosamide 1', 'ADD 243037', 'ADD-243037', 'Erlosamide', 'LacosamideLacosamide cv', 'SPM 927', 'SPM-927']", 'target': 'ENSG00000007314', 'approvedSymbol': 'SCN4A', 'approvedN... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.947 | Q6 | What genes does Temsirolimus target when it's used to treat malignant colon neoplasm? | Temsirolimus has not been approved by the FDA as a treatment for malignant colon neoplasm, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is FKBP1A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%temsirolimus%" OR LOWER(tradeNames_list) LIKE "%t... | [{'UUID': 'DrugTargetsIndication121923_text_1091035', 'drugName': 'Temsirolimus', 'tradeNames_list': "['Torisel']", 'syns_list': "['CCI-779', 'Temsirolimus']", 'target': 'ENSG00000088832', 'approvedSymbol': 'FKBP1A', 'approvedName': 'FKBP prolyl isomerase 1A', 'mesh_heading': 'Colonic Neoplasms', 'efo_term': 'malignant... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.348 | Q6 | What genes does Cyclosporine target when it's used to treat retinal vasculitis? | Cyclosporine has not been approved by the FDA as a treatment for retinal vasculitis, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is PPIA. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%cyclosporine%" OR LOWER(tradeNames_list) LIKE "%c... | [{'UUID': 'DrugTargetsIndication121923_text_1101263', 'drugName': 'Cyclosporine', 'tradeNames_list': "['Capimune', 'Capsorin', 'Cequa', 'Cyclosporine', 'Deximune', 'GengrafIkervis', 'Neoral', 'Optimmune', 'Restasis', 'Restasis multidoseSandimmun', 'Sandimmune', 'Sangcya', 'Vanquoral', 'Verkazia']", 'syns_list': "['27-4... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.606 | Q6 | What genes does Leuprolide Acetate target when it's used to treat prostate carcinoma? | When used to treat prostate carcinoma, the drug Leuprolide Acetate targets the gene GNRHR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%leuprolide acetate%" OR LOWER(tradeNames_list) LI... | [{'UUID': 'DrugTargetsIndication121923_text_1097114', 'drugName': 'Leuprolide Acetate', 'tradeNames_list': "['Carcinil', 'Eligard', 'Eligard kit', 'Fensolvi kit', 'Leuprolide acetateLeuprorelin', 'Lupron', 'Lupron Depot Ped', 'Lupron depotLupron depot-ped', 'Lupron depot-ped kit', 'Lutrate depot kit', 'Viadur']", 'syns... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.719 | Q6 | What genes does Methylphenidate target when it's used to treat attention deficit hyperactivity disorder? | When used to treat attention deficit hyperactivity disorder, the drug Methylphenidate targets the genes SLC6A2 and SLC6A3. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%methylphenidate%" OR LOWER(tradeNames_list) LIKE ... | [{'UUID': 'DrugTargetsIndication121923_text_435220', 'drugName': 'Methylphenidate Hydrochloride', 'tradeNames_list': "['Adhansia xr', 'Aptensio xr', 'Concerta', 'Delmosart', 'Equasym', 'Equasym xlJornay pm', 'Matoride xl', 'Medikinet', 'Medikinet xl', 'Metadate cdMetadate er', 'Methylin', 'Methylin er', 'Methylphenidat... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.118 | Q6 | What genes does Hydrocortisone Butyrate target when it's used to treat atopic eczema? | When used to treat atopic eczema, the drug Hydrocortisone Butyrate targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%hydrocortisone butyrate%" OR LOWER(tradeNames_lis... | [{'UUID': 'DrugTargetsIndication121923_text_243801', 'drugName': 'Hydrocortisone Butyrate', 'tradeNames_list': "['Hydrocortisone butyrate', 'Locoid', 'Locoid c', 'Locoid creloLocoid lipocream']", 'syns_list': "['Cortisol 17-butyrate', 'Hydrocortisone 17-butyrateHydrocortisone butyrate', 'Hydrocortisone-17-butyrate', 'N... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.617 | Q6 | What genes does Bupropion Hydrochloride target when it's used to treat depressive disorder? | When used to treat depressive disorder, the drug Bupropion Hydrochloride targets the genes SLC6A2 and SLC6A3. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%bupropion hydrochloride%" OR LOWER(tradeNames_lis... | [{'UUID': 'DrugTargetsIndication121923_text_434137', 'drugName': 'Bupropion Hydrochloride', 'tradeNames_list': "['Bupropion hydrochloride', 'Forfivo xl', 'Wellbutrin', 'Wellbutrin 100Wellbutrin 75', 'Wellbutrin sr', 'Wellbutrin xl', 'Zyban']", 'syns_list': "['Amfebutamone hydrochloride', 'BW 323', 'BW-323', 'BW323', 'B... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1013 | Q6 | What genes does Ticagrelor target when it's used to treat type 2 diabetes mellitus? | When used to treat type 2 diabetes mellitus, the drug Ticagrelor targets the gene P2RY12. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ticagrelor%" OR LOWER(tradeNames_list) LIKE "%tic... | [{'UUID': 'DrugTargetsIndication121923_text_920471', 'drugName': 'Ticagrelor', 'tradeNames_list': "['Brilinta', 'Brilique']", 'syns_list': "['AR-C126532XX', 'AZD-6140', 'AZD6140', 'Possia', 'Ticagrelor']", 'target': 'ENSG00000169313', 'approvedSymbol': 'P2RY12', 'approvedName': 'purinergic receptor P2Y12', 'mesh_headin... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1265 | Q6 | What genes does Idelalisib target when it's used to treat Waldenstrom macroglobulinemia? | Idelalisib has not been approved by the FDA as a treatment for Waldenstrom macroglobulinemia, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is PIK3CD. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%idelalisib%" OR LOWER(tradeNames_list) LIKE "%ide... | [{'UUID': 'DrugTargetsIndication121923_text_858429', 'drugName': 'Idelalisib', 'tradeNames_list': "['Zydelig']", 'syns_list': "['CAL-101', 'GS-1101', 'GS-11CAL-101', 'Idelalisib']", 'target': 'ENSG00000171608', 'approvedSymbol': 'PIK3CD', 'approvedName': 'phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1489 | Q6 | What genes does Perampanel target when it's used to treat epilepsy? | When used to treat epilepsy, the drug Perampanel targets the genes GRIA4, GRIA3, GRIA2, and GRIA1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%perampanel%" OR LOWER(tradeNames_list) LIKE "%per... | [{'UUID': 'DrugTargetsIndication121923_text_970921', 'drugName': 'Perampanel', 'tradeNames_list': "['Fycompa']", 'syns_list': "['E-2007', 'E2007', 'ER-155055-90', 'Perampanel']", 'target': 'ENSG00000125675', 'approvedSymbol': 'GRIA3', 'approvedName': 'glutamate ionotropic receptor AMPA type subunit 3', 'mesh_heading': ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.489 | Q6 | What genes does Duloxetine Hydrochloride target when it's used to treat unipolar depression? | When used to treat unipolar depression, the drug Duloxetine Hydrochloride targets the genes SLC6A4 and SLC6A2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%duloxetine hydrochloride%" OR LOWER(tradeNames_li... | [{'UUID': 'DrugTargetsIndication121923_text_206076', 'drugName': 'Duloxetine Hydrochloride', 'tradeNames_list': "['Ariclaim', 'Cymbalta', 'Drizalma sprinkle', 'DuciltiaDuloxetine hydrochloride', 'Yentreve']", 'syns_list': "['Ariclaim', 'Duloxetine (as hydrochloride)', 'Duloxetine hclDuloxetine hydrochloride', 'Duloxeti... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1711 | Q6 | What genes does Riluzole target when it's used to treat amyotrophic lateral sclerosis? | When used to treat amyotrophic lateral sclerosis, the drug Riluzole targets the genes SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%riluzole%" OR LOWER(tradeNames_list) LIKE "%riluz... | [{'UUID': 'DrugTargetsIndication121923_text_636339', 'drugName': 'Riluzole', 'tradeNames_list': "['Exservan', 'Rilutek', 'Riluzole', 'Teglutik', 'Tiglutik kit']", 'syns_list': "['BHV-0223', 'NSC-753433', 'NSC-759823', 'RP 54274', 'RP-54274', 'RiluzoleTiglutik']", 'target': 'ENSG00000183873', 'approvedSymbol': 'SCN5A', ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.787 | Q6 | What genes does Simvastatin target when it's used to treat cardiovascular disease? | When used to treat cardiovascular disease, the drug Simvastatin targets the gene HMGCR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%simvastatin%" OR LOWER(tradeNames_list) LIKE "%si... | [{'UUID': 'DrugTargetsIndication121923_text_1103896', 'drugName': 'Simvastatin', 'tradeNames_list': "['Flolipid', 'Lacersa', 'Ranzolont', 'Simvador', 'Simvastatin', 'ZocorZocor heart-pro']", 'syns_list': "['C10AA01', 'MK-0733', 'MK-733', 'NSC-758706', 'SimvastatinSimvastatin hydroxy acid', 'Synvinolin']", 'target': 'EN... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.881 | Q6 | What genes does Sorafenib target when it's used to treat non-small cell lung carcinoma? | Sorafenib has not been approved by the FDA as a treatment for non-small cell lung carcinoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are KDR, BRAF, FLT1, FLT3, KIT, FLT4, PDGFRB, RAF1, and RET. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%sorafenib%" OR LOWER(tradeNames_list) LIKE "%sora... | [{'UUID': 'DrugTargetsIndication121923_text_687898', 'drugName': 'Sorafenib', 'tradeNames_list': "['Nexavar']", 'syns_list': "['BAY 43-9006', 'BAY-43-9006', 'Sorafenib']", 'target': 'ENSG00000037280', 'approvedSymbol': 'FLT4', 'approvedName': 'fms related receptor tyrosine kinase 4', 'mesh_heading': 'Carcinoma, Non-Sma... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1555 | Q6 | What genes does Naproxen Sodium target when it's used to treat migraine disorder? | When used to treat migraine disorder, the drug Naproxen Sodium targets the genes PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%naproxen sodium%" OR LOWER(tradeNames_list) LIKE ... | [{'UUID': 'DrugTargetsIndication121923_text_838138', 'drugName': 'Naproxen Sodium', 'tradeNames_list': "['Aleve', 'Anaprox', 'Anaprox ds', 'Naprelan', 'Naproxen sodium', 'Synflex']", 'syns_list': "['BAY-117031', 'BAY117031', 'BAYH6689', 'Naproxen sodiumNaproxen sodium anhydrous', 'Naproxen sodium salt', 'RS-3650']", 't... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.567 | Q6 | What genes does Methylphenidate Hydrochloride target when it's used to treat chronic progressive multiple sclerosis? | Methylphenidate Hydrochloride has not been approved by the FDA as a treatment for chronic progressive multiple sclerosis, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are SLC6A2 and SLC6A3. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%methylphenidate hydrochloride%" OR LOWER(tradeNam... | [{'UUID': 'DrugTargetsIndication121923_text_435210', 'drugName': 'Methylphenidate Hydrochloride', 'tradeNames_list': "['Adhansia xr', 'Aptensio xr', 'Concerta', 'Delmosart', 'Equasym', 'Equasym xlJornay pm', 'Matoride xl', 'Medikinet', 'Medikinet xl', 'Metadate cdMetadate er', 'Methylin', 'Methylin er', 'Methylphenidat... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.254 | Q6 | What genes does Prednisone target when it's used to treat ulcerative colitis? | When used to treat ulcerative colitis, the drug Prednisone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%prednisone%" OR LOWER(tradeNames_list) LIKE "%pre... | [{'UUID': 'DrugTargetsIndication121923_text_218675', 'drugName': 'Prednisone', 'tradeNames_list': "['Cortan', 'Cortancyl', 'Decortisyl', 'Delta-dome', 'Deltasone', 'FernisoneLiquid pred', 'Lodotra', 'Meticorten', 'Orasone', 'Paracort', 'Prednicen-mPrednisone', 'Prednisone intensol', 'Rayos', 'Servisone', 'Sterapred']",... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.242 | Q6 | What genes does Fludarabine Phosphate target when it's used to treat squamous cell lung carcinoma? | Fludarabine Phosphate has not been approved by the FDA as a treatment for squamous cell lung carcinoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are POLA1, POLD4, POLD3, POLD1, POLD2, POLE, POLA2, PRIM1, PRIM2, POLE2, POLE3, RRM1, RRM2B, and RRM2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fludarabine phosphate%" OR LOWER(tradeNames_list)... | [{'UUID': 'DrugTargetsIndication121923_text_754517', 'drugName': 'Fludarabine Phosphate', 'tradeNames_list': "['Fludara', 'Fludarabine phosphate', 'Oforta']", 'syns_list': '[\'2-f-ara-amp\', \'2-f-araa\', \'2-fluoro ara-a\', \'2-fluorovidarabineFludarabine\', "Fludarabine 5\'-monophosphateFludarabine monophosphateFluda... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.176 | Q6 | What genes does Indacaterol Maleate target when it's used to treat chronic bronchitis? | When used to treat chronic bronchitis, the drug Indacaterol Maleate targets the gene ADRB2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%indacaterol maleate%" OR LOWER(tradeNames_list) L... | [{'UUID': 'DrugTargetsIndication121923_text_937189', 'drugName': 'Indacaterol Maleate', 'tradeNames_list': "['Arcapta neohaler', 'Onbrez breezhaler']", 'syns_list': "['Indacaterol (as maleate)', 'Indacaterol maleate', 'Indacterol maleateQAB-149-AFA', 'QAB149-AFA']", 'target': 'ENSG00000169252', 'approvedSymbol': 'ADRB2... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.824 | Q6 | What genes does Travoprost target when it's used to treat open-angle glaucoma? | When used to treat open-angle glaucoma, the drug Travoprost targets the gene PTGFR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%travoprost%" OR LOWER(tradeNames_list) LIKE "%tra... | [{'UUID': 'DrugTargetsIndication121923_text_1149427', 'drugName': 'Travoprost', 'tradeNames_list': "['Izba', 'Travatan', 'Travatan z', 'Travoprost']", 'syns_list': "['AL-6221', 'NSC-760366', 'Otx-tp', 'Travoprost']", 'target': 'ENSG00000122420', 'approvedSymbol': 'PTGFR', 'approvedName': 'prostaglandin F receptor', 'me... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.983 | Q6 | What genes does Dexamethasone target when it's used to treat xerostomia? | Dexamethasone has not been approved by the FDA as a treatment for xerostomia, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dexamethasone%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_227588', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1476 | Q6 | What genes does Ezetimibe target when it's used to treat homozygous familial hypercholesterolemia? | When used to treat homozygous familial hypercholesterolemia, the drug Ezetimibe targets the gene NPC1L1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ezetimibe%" OR LOWER(tradeNames_list) LIKE "%ezet... | [{'UUID': 'DrugTargetsIndication121923_text_1097390', 'drugName': 'Ezetimibe', 'tradeNames_list': "['Ezetimibe', 'Ezetrol', 'Zetia']", 'syns_list': "['Ezetimibe', 'MK0653', 'NSC-758923', 'SCH-58235', 'SCH58235']", 'target': 'ENSG00000015520', 'approvedSymbol': 'NPC1L1', 'approvedName': 'NPC1 like intracellular choleste... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1262 | Q6 | What genes does Propranolol Hydrochloride target when it's used to treat Wolff-Parkinson-White Syndrome? | When used to treat Wolff-Parkinson-White Syndrome, the drug Propranolol Hydrochloride targets the genes ADRB2 and ADRB1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%propranolol hydrochloride%" OR LOWER(tradeNames_l... | [{'UUID': 'DrugTargetsIndication121923_text_937044', 'drugName': 'Propranolol Hydrochloride', 'tradeNames_list': "['Angilol', 'Apsolol', 'Avlocardyl', 'Bedranol', 'Bedranol s.r.', 'BerkololBeta-prograne mr', 'Betadur cr', 'Cardinol', 'DupromexHalf beta-prograne mr', 'Half propanix la', 'Half propatard laHalf-beprane cr... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1280 | Q6 | What genes does Temsirolimus target when it's used to treat kidney cancer? | Temsirolimus has not been approved by the FDA as a treatment for kidney cancer, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is FKBP1A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%temsirolimus%" OR LOWER(tradeNames_list) LIKE "%t... | [{'UUID': 'DrugTargetsIndication121923_text_1091072', 'drugName': 'Temsirolimus', 'tradeNames_list': "['Torisel']", 'syns_list': "['CCI-779', 'Temsirolimus']", 'target': 'ENSG00000088832', 'approvedSymbol': 'FKBP1A', 'approvedName': 'FKBP prolyl isomerase 1A', 'mesh_heading': 'Kidney Neoplasms', 'efo_term': 'kidney can... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.751 | Q6 | What genes does Diclofenac Potassium target when it's used to treat rheumatoid arthritis? | When used to treat rheumatoid arthritis, the drug Diclofenac Potassium targets the genes PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%diclofenac potassium%" OR LOWER(tradeNames_list) ... | [{'UUID': 'DrugTargetsIndication121923_text_842935', 'drugName': 'Diclofenac Potassium', 'tradeNames_list': "['Cambia', 'Cataflam', 'Diclofenac potassium', 'Voltarol joint painVoltarol pain-eze', 'Voltarol pain-eze extra strgh', 'Voltarol rapidZipsor']", 'syns_list': "['CGP 45840B', 'CGP-45840B', 'Diclofenac potassiumD... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.561 | Q6 | What genes does Prednisone target when it's used to treat dermatomyositis? | When used to treat dermatomyositis, the drug Prednisone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%prednisone%" OR LOWER(tradeNames_list) LIKE "%pre... | [{'UUID': 'DrugTargetsIndication121923_text_218046', 'drugName': 'Prednisone', 'tradeNames_list': "['Cortan', 'Cortancyl', 'Decortisyl', 'Delta-dome', 'Deltasone', 'FernisoneLiquid pred', 'Lodotra', 'Meticorten', 'Orasone', 'Paracort', 'Prednicen-mPrednisone', 'Prednisone intensol', 'Rayos', 'Servisone', 'Sterapred']",... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.81 | Q6 | What genes does Naproxen target when it's used to treat ankylosing spondylitis? | When used to treat ankylosing spondylitis, the drug Naproxen targets the genes PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%naproxen%" OR LOWER(tradeNames_list) LIKE "%napro... | [{'UUID': 'DrugTargetsIndication121923_text_838133', 'drugName': 'Naproxen Sodium', 'tradeNames_list': "['Aleve', 'Anaprox', 'Anaprox ds', 'Naprelan', 'Naproxen sodium', 'Synflex']", 'syns_list': "['BAY-117031', 'BAY117031', 'BAYH6689', 'Naproxen sodiumNaproxen sodium anhydrous', 'Naproxen sodium salt', 'RS-3650']", 't... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1042 | Q6 | What genes does Fluticasone Propionate target when it's used to treat allergic rhinitis? | When used to treat allergic rhinitis, the drug Fluticasone Propionate targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fluticasone propionate%" OR LOWER(tradeNames_list... | [{'UUID': 'DrugTargetsIndication121923_text_232452', 'drugName': 'Fluticasone Propionate', 'tradeNames_list': "['Aerivio spiromax', 'Airflusal forspiro', 'Armonair digihalerArmonair respiclick', 'Cutivate', 'Flixonase', 'Flixotide', 'FlonaseFlonase allergy relief', 'Flovent', 'Flovent diskus 100Flovent diskus 250', 'Fl... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1314 | Q6 | What genes does Triamcinolone Acetonide target when it's used to treat epicondylitis? | When used to treat epicondylitis, the drug Triamcinolone Acetonide targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%triamcinolone acetonide%" OR LOWER(tradeNames_lis... | [{'UUID': 'DrugTargetsIndication121923_text_222015', 'drugName': 'Triamcinolone Acetonide', 'tradeNames_list': "['Adcortyl', 'Adcortyl in orabase', 'Allernaze', 'Aristocort', 'Aristocort aAristogel', 'Audicort', 'Aureocort', 'Azmacort', 'Flutex', 'Gppe ear dps capGppe ear oint', 'Kenacort', 'Kenalog', 'Kenalog in oraba... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.33 | Q6 | What genes does Dexamethasone target when it's used to treat systemic lupus erythematosus? | When used to treat systemic lupus erythematosus, the drug Dexamethasone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dexamethasone%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_227756', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1739 | Q6 | What genes does Amantadine Hydrochloride target when it's used to treat schizophrenia? | Amantadine Hydrochloride has not been approved by the FDA as a treatment for schizophrenia, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are GRIN1, GRIN2A, GRIN2B, GRIN2D, GRIN3B, GRIN2C, and GRIN3A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%amantadine hydrochloride%" OR LOWER(tradeNames_li... | [{'UUID': 'DrugTargetsIndication121923_text_441083', 'drugName': 'Amantadine Hydrochloride', 'tradeNames_list': "['Amantadine hydrochloride', 'Gocovri', 'Lysovir', 'Mantadine', 'Osmolex erSymadine', 'Symmetrel']", 'syns_list': "['Adamantanamine hydrochloride', 'Amantadine hclAmantadine hydrochloride', 'EXP-105-1', 'Man... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.358 | Q6 | What genes does Estradiol target when it's used to treat menopause? | Estradiol has not been approved by the FDA as a treatment for menopause, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is ESR1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%estradiol%" OR LOWER(tradeNames_list) LIKE "%estr... | [{'UUID': 'DrugTargetsIndication121923_text_823877', 'drugName': 'Estradiol Acetate', 'tradeNames_list': "['Femring', 'Femtrace']", 'syns_list': "['E3A', 'ESTRADIOL-3-ACETATE', 'Estradiol 3-acetate', 'Estradiol acetate']", 'target': 'ENSG00000091831', 'approvedSymbol': 'ESR1', 'approvedName': 'estrogen receptor 1', 'me... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1077 | Q6 | What genes does Dantrolene Sodium target when it's used to treat stroke? | When used to treat stroke, the drug Dantrolene Sodium targets the genes RYR3 and RYR1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dantrolene sodium%" OR LOWER(tradeNames_list) LIK... | [{'UUID': 'DrugTargetsIndication121923_text_1100247', 'drugName': 'Dantrolene Sodium', 'tradeNames_list': "['Dantrium', 'Dantrolene sodium', 'Revonto', 'Ryanodex']", 'syns_list': "['Dantamacrin', 'Dantrolen', 'Dantrolene sodiumDantrolene sodium heptahydrate', 'Dantrolene sodium hydrateDantrolene sodium salt hemiheptahy... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1692 | Q6 | What genes does Fedratinib Hydrochloride target when it's used to treat Myelofibrosis? | When used to treat Myelofibrosis, the drug Fedratinib Hydrochloride targets the genes FLT3 and JAK2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fedratinib hydrochloride%" OR LOWER(tradeNames_li... | [{'UUID': 'DrugTargetsIndication121923_text_933946', 'drugName': 'Fedratinib Hydrochloride', 'tradeNames_list': "['Inrebic']", 'syns_list': "['Fedratinib hydrochloride', 'SAR302503A']", 'target': 'ENSG00000122025', 'approvedSymbol': 'FLT3', 'approvedName': 'fms related receptor tyrosine kinase 3', 'mesh_heading': 'Prim... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.127 | Q6 | What genes does Entrectinib target when it's used to treat non-small cell lung carcinoma? | When used to treat non-small cell lung carcinoma, the drug Entrectinib targets the genes NTRK1, ALK, NTRK2, NTRK3, and ROS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%entrectinib%" OR LOWER(tradeNames_list) LIKE "%en... | [{'UUID': 'DrugTargetsIndication121923_text_943002', 'drugName': 'Entrectinib', 'tradeNames_list': "['Rozlytrek']", 'syns_list': "['Entrectinib', 'NMS-E628', 'RXDX-101', 'Rxdx-101']", 'target': 'ENSG00000198400', 'approvedSymbol': 'NTRK1', 'approvedName': 'neurotrophic receptor tyrosine kinase 1', 'mesh_heading': 'Carc... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1031 | Q6 | What genes does Cyclosporine target when it's used to treat leukemia? | Cyclosporine has not been approved by the FDA as a treatment for leukemia, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is PPIA. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%cyclosporine%" OR LOWER(tradeNames_list) LIKE "%c... | [{'UUID': 'DrugTargetsIndication121923_text_1101616', 'drugName': 'Cyclosporine', 'tradeNames_list': "['Capimune', 'Capsorin', 'Cequa', 'Cyclosporine', 'Deximune', 'GengrafIkervis', 'Neoral', 'Optimmune', 'Restasis', 'Restasis multidoseSandimmun', 'Sandimmune', 'Sangcya', 'Vanquoral', 'Verkazia']", 'syns_list': "['27-4... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.399 | Q6 | What genes does Tafamidis target when it's used to treat AL amyloidosis? | When used to treat AL amyloidosis, the drug Tafamidis targets the gene TTR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%tafamidis%" OR LOWER(tradeNames_list) LIKE "%tafa... | [{'UUID': 'DrugTargetsIndication121923_text_1097617', 'drugName': 'Tafamidis', 'tradeNames_list': "['Vyndamax', 'Vyndaqel']", 'syns_list': "['FX-1005', 'FX-1006', 'FX1006', 'Tafamidis']", 'target': 'ENSG00000118271', 'approvedSymbol': 'TTR', 'approvedName': 'transthyretin', 'mesh_heading': 'Amyloidosis, Familial', 'efo... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.444 | Q6 | What genes does Ozanimod Hydrochloride target when it's used to treat multiple sclerosis? | When used to treat multiple sclerosis, the drug Ozanimod Hydrochloride targets the gene S1PR1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ozanimod hydrochloride%" OR LOWER(tradeNames_list... | [{'UUID': 'DrugTargetsIndication121923_text_1036807', 'drugName': 'Ozanimod Hydrochloride', 'tradeNames_list': "['Zeposia']", 'syns_list': "['Ozanimod hydrochloride', 'RPC-1063 HCL', 'RPC1063 HCL']", 'target': 'ENSG00000170989', 'approvedSymbol': 'S1PR1', 'approvedName': 'sphingosine-1-phosphate receptor 1', 'mesh_head... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.166 | Q6 | What genes does Donepezil Hydrochloride target when it's used to treat Alzheimer disease? | When used to treat Alzheimer disease, the drug Donepezil Hydrochloride targets the gene ACHE. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%donepezil hydrochloride%" OR LOWER(tradeNames_lis... | [{'UUID': 'DrugTargetsIndication121923_text_993848', 'drugName': 'Donepezil Hydrochloride', 'tradeNames_list': "['Adlarity', 'Aricept', 'Aricept evess', 'Aricept odtDonepezil hydrochloride']", 'syns_list': "['Adlarity', 'BNAG', 'Donepezil hcl', 'Donepezil hydrochloride', 'E-2020E2020', 'NSC-737535', 'NSC-758882']", 'ta... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.206 | Q6 | What genes does Dexamethasone target when it's used to treat myocarditis? | When used to treat myocarditis, the drug Dexamethasone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dexamethasone%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_227782', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1571 | Q6 | What genes does Pemigatinib target when it's used to treat urogenital neoplasm? | Pemigatinib has not been approved by the FDA as a treatment for urogenital neoplasm, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are FGFR1, FGFR3, and FGFR2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%pemigatinib%" OR LOWER(tradeNames_list) LIKE "%pe... | [{'UUID': 'DrugTargetsIndication121923_text_706917', 'drugName': 'Pemigatinib', 'tradeNames_list': "['Pemazyre']", 'syns_list': "['Fgfr inhibitor incb054828', 'INCB054828', 'Incb-054828', 'Incb054828Pemigatinib']", 'target': 'ENSG00000077782', 'approvedSymbol': 'FGFR1', 'approvedName': 'fibroblast growth factor recepto... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1641 | Q6 | What genes does Sumatriptan Succinate target when it's used to treat migraine disorder? | When used to treat migraine disorder, the drug Sumatriptan Succinate targets the genes HTR1B and HTR1D. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%sumatriptan succinate%" OR LOWER(tradeNames_list)... | [{'UUID': 'DrugTargetsIndication121923_text_937284', 'drugName': 'Sumatriptan Succinate', 'tradeNames_list': "['Alsuma', 'Imigran', 'Imigran 50', 'Imigran radis', 'Imigran recoveryImigran subject', 'Imitrex', 'Imitrex statdose', 'MigraitanMigraleve ultra', 'Onzetra xsail', 'Sumatriptan succinateSumavel dosepro', 'Zecui... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1565 | Q6 | What genes does Prednisone target when it's used to treat posterior uveitis? | When used to treat posterior uveitis, the drug Prednisone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%prednisone%" OR LOWER(tradeNames_list) LIKE "%pre... | [{'UUID': 'DrugTargetsIndication121923_text_218711', 'drugName': 'Prednisone', 'tradeNames_list': "['Cortan', 'Cortancyl', 'Decortisyl', 'Delta-dome', 'Deltasone', 'FernisoneLiquid pred', 'Lodotra', 'Meticorten', 'Orasone', 'Paracort', 'Prednicen-mPrednisone', 'Prednisone intensol', 'Rayos', 'Servisone', 'Sterapred']",... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.491 | Q6 | What genes does Cannabidiol target when it's used to treat Cognitive impairment? | Cannabidiol has not been approved by the FDA as a treatment for Cognitive impairment, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is CNR1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%cannabidiol%" OR LOWER(tradeNames_list) LIKE "%ca... | [{'UUID': 'DrugTargetsIndication121923_text_1073766', 'drugName': 'Cannabidiol', 'tradeNames_list': "['Epidiolex']", 'syns_list': "['(-)-cannabidiol', '(-)-cbd', '(-)-trans-cannabidiol.delta.1(2)-trans-cannabidiol', 'BTX-1204', 'BTX-1503', 'CBD', 'CannabidiolCannabidiol solution', 'Cardiolrx', 'GWP-42003', 'GWP-42003-P... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1966 | Q6 | What genes does Aprepitant target when it's used to treat cancer? | When used to treat cancer, the drug Aprepitant targets the gene TACR1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%aprepitant%" OR LOWER(tradeNames_list) LIKE "%apr... | [{'UUID': 'DrugTargetsIndication121923_text_1072873', 'drugName': 'Aprepitant', 'tradeNames_list': "['Aprepitant', 'Cinvanti', 'Emend']", 'syns_list': "['Aprepitant', 'L-754,030', 'MK-0869', 'MK-869', 'NSC-748825']", 'target': 'ENSG00000115353', 'approvedSymbol': 'TACR1', 'approvedName': 'tachykinin receptor 1', 'mesh_... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1800 | Q6 | What genes does Desvenlafaxine target when it's used to treat major depressive disorder? | When used to treat major depressive disorder, the drug Desvenlafaxine targets the genes SLC6A4 and SLC6A2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%desvenlafaxine%" OR LOWER(tradeNames_list) LIKE "... | [{'UUID': 'DrugTargetsIndication121923_text_206639', 'drugName': 'Desvenlafaxine', 'tradeNames_list': "['Desvenlafaxine', 'Khedezla', 'Pristiq']", 'syns_list': "['D-veniz', 'Desvenlafaxine', 'Mdd-xr', 'Newven', 'O-desmethylvenlafaxineODV']", 'target': 'ENSG00000108576', 'approvedSymbol': 'SLC6A4', 'approvedName': 'solu... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1330 | Q6 | What genes does Aspirin target when it's used to treat Muscle spasm? | When used to treat Muscle spasm, the drug Aspirin targets the genes PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%aspirin%" OR LOWER(tradeNames_list) LIKE "%aspiri... | [{'UUID': 'DrugTargetsIndication121923_text_834427', 'drugName': 'Aspirin', 'tradeNames_list': "['8-hour bayer', 'Acetosalic Acid', 'Acetylsalic acidAcetylsalicylic Acid', 'Alka rapid', 'Anadin all night', 'Angettes 75Aspirin', 'Aspro clr', 'Bayer extra strength aspirin for migraine painDanamep', 'Disprin cv', 'Disprin... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.285 | Q6 | What genes does Solifenacin Succinate target when it's used to treat urgency urinary incontinence? | When used to treat urgency urinary incontinence, the drug Solifenacin Succinate targets the genes CHRM3 and CHRM2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%solifenacin succinate%" OR LOWER(tradeNames_list)... | [{'UUID': 'DrugTargetsIndication121923_text_857279', 'drugName': 'Solifenacin Succinate', 'tradeNames_list': "['Solifenacin succinate', 'Vesicare', 'Vesicare ls']", 'syns_list': "['Solifenacin succinate', 'YM-67905', 'YM-905', 'YM67905', 'YM905']", 'target': 'ENSG00000133019', 'approvedSymbol': 'CHRM3', 'approvedName':... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1375 | Q6 | What genes does Patisiran Sodium target when it's used to treat amyloidosis? | When used to treat amyloidosis, the drug Patisiran Sodium targets the gene TTR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%patisiran sodium%" OR LOWER(tradeNames_list) LIKE... | [{'UUID': 'DrugTargetsIndication121923_text_1097701', 'drugName': 'Patisiran Sodium', 'tradeNames_list': "['Onpattro']", 'syns_list': "['Patisiran sodium']", 'target': 'ENSG00000118271', 'approvedSymbol': 'TTR', 'approvedName': 'transthyretin', 'mesh_heading': 'Amyloidosis', 'efo_term': 'amyloidosis', 'yearOfFirstAppro... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.221 | Q6 | What genes does Guanfacine Hydrochloride target when it's used to treat hypertension? | When used to treat hypertension, the drug Guanfacine Hydrochloride targets the genes ADRA2A, ADRA2C, and ADRA2B. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%guanfacine hydrochloride%" OR LOWER(tradeNames_li... | [{'UUID': 'DrugTargetsIndication121923_text_1025306', 'drugName': 'Guanfacine Hydrochloride', 'tradeNames_list': "['Akfen', 'Estulic', 'Guanfacine hydrochloride', 'Intuniv', 'Tenex']", 'syns_list': "['BS 100-141', 'BS-100-141', 'Guafacine hydrochloride', 'Guanfacine hclGuanfacine hydrochloride', 'SPD503']", 'target': '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1931 | Q6 | What genes does Pexidartinib Hydrochloride target when it's used to treat Tenosynovial Giant Cell Tumor? | When used to treat Tenosynovial Giant Cell Tumor, the drug Pexidartinib Hydrochloride targets the genes FLT3, KIT, and CSF1R. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%pexidartinib hydrochloride%" OR LOWER(tradeNames_... | [{'UUID': 'DrugTargetsIndication121923_text_933898', 'drugName': 'Pexidartinib Hydrochloride', 'tradeNames_list': "['Turalio']", 'syns_list': "['FP-113', 'PLX-3397 HCL', 'PLX3397 HCl', 'Pexidartinib hydrochloride']", 'target': 'ENSG00000122025', 'approvedSymbol': 'FLT3', 'approvedName': 'fms related receptor tyrosine k... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.888 | Q6 | What genes does Fluocinolone Acetonide target when it's used to treat infectious disease? | When used to treat infectious disease, the drug Fluocinolone Acetonide targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fluocinolone acetonide%" OR LOWER(tradeNames_list... | [{'UUID': 'DrugTargetsIndication121923_text_242237', 'drugName': 'Fluocinolone Acetonide', 'tradeNames_list': "['Capex', 'Derma-smoothe/fs', 'Dermotic', 'Fluocet', 'Fluocinolone acetonideFluonid', 'Fluotrex', 'Fs shampoo', 'Iluvien', 'Retisert', 'SynalarSynalar fte', 'Synalar-c', 'Synalar-hp', 'Synalar-n', 'Synandone',... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1623 | Q6 | What genes does Baclofen target when it's used to treat Rigidity? | When used to treat Rigidity, the drug Baclofen targets the genes GABBR1 and GABBR2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%baclofen%" OR LOWER(tradeNames_list) LIKE "%baclo... | [{'UUID': 'DrugTargetsIndication121923_text_1193244', 'drugName': 'Baclofen', 'tradeNames_list': "['Baclofen', 'Baclospas-10', 'Fleqsuvy', 'Gablofen', 'Kemstro', 'LioresalLioresal intrath', 'Lyflex', 'Lyvispah', 'Ozobax']", 'syns_list': "['(rs)-baclofen', 'BA-34,647', 'BA-34647', 'Baclofen', 'Fleqsuvy', 'LyvispahNSC-75... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.701 | Q6 | What genes does Pemetrexed target when it's used to treat biliary tract cancer? | Pemetrexed has not been approved by the FDA as a treatment for biliary tract cancer, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are TYMS, GART, and DHFR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%pemetrexed%" OR LOWER(tradeNames_list) LIKE "%pem... | [{'UUID': 'DrugTargetsIndication121923_text_918775', 'drugName': 'Pemetrexed', 'tradeNames_list': "['Alimta', 'Pemfexy']", 'syns_list': "['LY-2315', 'LY-231514', 'LY231514', 'NSC-698037', 'Pemetrexed']", 'target': 'ENSG00000159131', 'approvedSymbol': 'GART', 'approvedName': 'phosphoribosylglycinamide formyltransferase,... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.61 | Q6 | What genes does Everolimus target when it's used to treat neuroendocrine neoplasm? | When used to treat neuroendocrine neoplasm, the drug Everolimus targets the gene FKBP1A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%everolimus%" OR LOWER(tradeNames_list) LIKE "%eve... | [{'UUID': 'DrugTargetsIndication121923_text_1087126', 'drugName': 'Everolimus', 'tradeNames_list': "['Afinitor', 'Afinitor disperz', 'Certican', 'Votubia', 'Zortress']", 'syns_list': "['40-o-(2-hydroxyethyl)-rapamycin', 'Everolimus', 'RAD 666', 'RAD-001RAD-666', 'RAD001', 'SDZ-RAD', 'Sdz rad']", 'target': 'ENSG00000088... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.843 | Q6 | What genes does Risperidone target when it's used to treat major depressive disorder? | Risperidone has not been approved by the FDA as a treatment for major depressive disorder, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are HTR2C, DRD2, and HTR2A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%risperidone%" OR LOWER(tradeNames_list) LIKE "%ri... | [{'UUID': 'DrugTargetsIndication121923_text_149648', 'drugName': 'Risperidone', 'tradeNames_list': "['Perseris kit', 'Risperdal', 'Risperdal Consta Long Acting', 'Risperdal MRisperdal M-Tab', 'Risperdal consta', 'Risperdal quicklet', 'Risperidone']", 'syns_list': "['LY-03004', 'LY03004', 'N05AX08', 'NSC-759895', 'Perse... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1356 | Q6 | What genes does Simvastatin target when it's used to treat Combined hyperlipidemia? | Simvastatin has not been approved by the FDA as a treatment for Combined hyperlipidemia, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is HMGCR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%simvastatin%" OR LOWER(tradeNames_list) LIKE "%si... | [{'UUID': 'DrugTargetsIndication121923_text_1103892', 'drugName': 'Simvastatin', 'tradeNames_list': "['Flolipid', 'Lacersa', 'Ranzolont', 'Simvador', 'Simvastatin', 'ZocorZocor heart-pro']", 'syns_list': "['C10AA01', 'MK-0733', 'MK-733', 'NSC-758706', 'SimvastatinSimvastatin hydroxy acid', 'Synvinolin']", 'target': 'EN... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.76 | Q6 | What genes does Dronabinol target when it's used to treat Nausea and vomiting? | When used to treat Nausea and vomiting, the drug Dronabinol targets the gene CNR1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dronabinol%" OR LOWER(tradeNames_list) LIKE "%dro... | [{'UUID': 'DrugTargetsIndication121923_text_1073292', 'drugName': 'Dronabinol', 'tradeNames_list': "['Dronabinol', 'Marinol', 'Syndros']", 'syns_list': "['.delta.-9-tetrahydrocannabinol', '.delta.1-thc.delta.9-tetrahydrocannabinol', '.delta.9-thc', 'ABBOTT 40566ABBOTT-40566', 'Delta-9-tetrahydrocannabinol', 'Delta-9-th... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.165 | Q6 | What genes does Dasatinib target when it's used to treat gliosarcoma? | Dasatinib has not been approved by the FDA as a treatment for gliosarcoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are ABL1, BCR, HCK, SRC, LYN, KIT, PDGFRB, EPHA2, FRK, FYN, LCK, YES1, BLK, FGR, and SRMS. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dasatinib%" OR LOWER(tradeNames_list) LIKE "%dasa... | [{'UUID': 'DrugTargetsIndication121923_text_713582', 'drugName': 'Dasatinib', 'tradeNames_list': "['Dasatinib', 'Sprycel']", 'syns_list': "['BMS-354825', 'BMS-354825 HYDRATE', 'BMS-354825-03', 'DasatinibDasatinib anhydrous', 'Dasatinib hydrate', 'Dasatinib monohydrateNSC-759877']", 'target': 'ENSG00000097007', 'approve... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.576 | Q6 | What genes does Spironolactone target when it's used to treat myocardial infarction? | When used to treat myocardial infarction, the drug Spironolactone targets the gene NR3C2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%spironolactone%" OR LOWER(tradeNames_list) LIKE "... | [{'UUID': 'DrugTargetsIndication121923_text_1094351', 'drugName': 'Spironolactone', 'tradeNames_list': "['Abbolactone', 'Aldactone', 'Carospir', 'Diatensec', 'Gx spironolLaractone', 'Spiretic', 'Spiroctan 100', 'Spiroctan 25', 'Spiroctan 50Spironolactone', 'Spirospare 100', 'Spirospare 25']", 'syns_list': "['NSC-150399... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.959 | Q6 | What genes does Mometasone Furoate target when it's used to treat seasonal allergic rhinitis? | When used to treat seasonal allergic rhinitis, the drug Mometasone Furoate targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%mometasone furoate%" OR LOWER(tradeNames_list) LI... | [{'UUID': 'DrugTargetsIndication121923_text_242040', 'drugName': 'Mometasone Furoate', 'tradeNames_list': "['Asmanex', 'Asmanex hfa', 'Asmanex twisthaler', 'EloconMometasone furoate', 'Nasonex', 'Nasonex 24hr allergy', 'Sinuva']", 'syns_list': "['LAS-41002', 'LAS41002', 'LYR-210', 'LYR210', 'Lyr-210', 'MometasoneMometa... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1540 | Q6 | What genes does Fluticasone Propionate target when it's used to treat Nasal polyposis? | When used to treat Nasal polyposis, the drug Fluticasone Propionate targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fluticasone propionate%" OR LOWER(tradeNames_list... | [{'UUID': 'DrugTargetsIndication121923_text_232527', 'drugName': 'Fluticasone Propionate', 'tradeNames_list': "['Aerivio spiromax', 'Airflusal forspiro', 'Armonair digihalerArmonair respiclick', 'Cutivate', 'Flixonase', 'Flixotide', 'FlonaseFlonase allergy relief', 'Flovent', 'Flovent diskus 100Flovent diskus 250', 'Fl... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1046 | Q6 | What genes does Levetiracetam target when it's used to treat epilepsy? | When used to treat epilepsy, the drug Levetiracetam targets the genes CACNA1B and SV2A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%levetiracetam%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_915656', 'drugName': 'Levetiracetam', 'tradeNames_list': "['Desitrend', 'Elepsia xr', 'Keppra', 'Keppra xr', 'LevetiracetamLevetiracetam in sodium chloride', 'Matever', 'Spritam']", 'syns_list': "['AGB-101', 'Elepsia', 'Levetiracetam', 'Levetiracetam accordLevetiracetam actav... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1706 | Q6 | What genes does Fosphenytoin Sodium target when it's used to treat Seizure? | When used to treat Seizure, the drug Fosphenytoin Sodium targets the genes SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fosphenytoin sodium%" OR LOWER(tradeNames_list) L... | [{'UUID': 'DrugTargetsIndication121923_text_632027', 'drugName': 'Fosphenytoin Sodium', 'tradeNames_list': "['Cerebyx', 'Fosphenytoin sodium', 'Pro-epanutin', 'Sesquient']", 'syns_list': "['ACC-9653-010', 'ACC-9653-010 (SODIUM SALT)', 'CI 982', 'CI-982Fosphenytoin disodium salt', 'Fosphenytoin sodium']", 'target': 'ENS... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.513 | Q6 | What genes does Nitroglycerin target when it's used to treat heart failure? | When used to treat heart failure, the drug Nitroglycerin targets the genes GUCY1B1, GUCY1B2, GUCY1A2, and GUCY1A1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%nitroglycerin%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_972547', 'drugName': 'Nitroglycerin', 'tradeNames_list': "['Coro-nitro', 'Deponit 10', 'Deponit 5', 'Glytrin', 'Gonitro', 'Lenitral 7.5Minitran', 'Minitran 10', 'Minitran 15', 'Minitran 5', 'NatiroseNitriderm tts', 'Nitro iv', 'Nitro-bid', 'Nitro-dur', 'Nitro-mack retNitrocin... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.46 | Q6 | What genes does Zoledronic Acid target when it's used to treat prostate cancer? | When used to treat prostate cancer, the drug Zoledronic Acid targets the gene FDPS. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%zoledronic acid%" OR LOWER(tradeNames_list) LIKE ... | [{'UUID': 'DrugTargetsIndication121923_text_1099718', 'drugName': 'Zoledronic Acid', 'tradeNames_list': "['Aclasta', 'Reclast', 'Zerlinda', 'Zoledronic acid', 'Zometa']", 'syns_list': "['AK-156', 'Anhydrous zoledronic acid', 'CGP 42446', 'CGP-42446', 'CGP-42446ANSC-721517', 'Zoladrona acid mylan', 'Zoledronate', 'Zoled... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
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