uuid stringlengths 4 8 | template_uuid stringclasses 40
values | question stringlengths 13 193 | answer stringlengths 29 2.2k | benchmark_query stringlengths 133 622 | execution_results stringlengths 2 1.14M | query_type stringclasses 2
values | sql_category stringclasses 26
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Q6.1339 | Q6 | What genes does Abrocitinib target when it's used to treat Eczema? | When used to treat Eczema, the drug Abrocitinib targets the gene JAK1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%abrocitinib%" OR LOWER(tradeNames_list) LIKE "%ab... | [{'UUID': 'DrugTargetsIndication121923_text_848695', 'drugName': 'Abrocitinib', 'tradeNames_list': "['Cibinqo']", 'syns_list': "['Abrocitinib', 'Cibinqo', 'PF-04965842', 'Pf-04965842']", 'target': 'ENSG00000162434', 'approvedSymbol': 'JAK1', 'approvedName': 'Janus kinase 1', 'mesh_heading': 'Dermatitis, Atopic', 'efo_t... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.243 | Q6 | What genes does Palbociclib target when it's used to treat breast cancer? | When used to treat breast cancer, the drug Palbociclib targets the genes CDK4, CDK6, and CCND1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%palbociclib%" OR LOWER(tradeNames_list) LIKE "%pa... | [{'UUID': 'DrugTargetsIndication121923_text_851579', 'drugName': 'Palbociclib', 'tradeNames_list': "['Ibrance']", 'syns_list': "['PD-0332991', 'Palbociclib']", 'target': 'ENSG00000135446', 'approvedSymbol': 'CDK4', 'approvedName': 'cyclin dependent kinase 4', 'mesh_heading': 'Breast Neoplasms', 'efo_term': 'breast canc... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1010 | Q6 | What genes does Naproxen target when it's used to treat gastric ulcer? | When used to treat gastric ulcer, the drug Naproxen targets the genes PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%naproxen%" OR LOWER(tradeNames_list) LIKE "%napro... | [{'UUID': 'DrugTargetsIndication121923_text_839285', 'drugName': 'Naproxen', 'tradeNames_list': "['Aleve', 'Anaprox', 'Arthrosin 250', 'Arthrosin 250 ec', 'Arthrosin 500Arthrosin 500 ec', 'Condrotec', 'Ec-naprosyn', 'Equiproxen', 'Feminax ultraGrenoxal', 'Kenosyn', 'Laraflex', 'Napratec op', 'Naprosyn', 'Naprosyn 375Na... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.685 | Q6 | What genes does Levothyroxine Sodium target when it's used to treat bipolar disorder? | Levothyroxine Sodium has not been approved by the FDA as a treatment for bipolar disorder, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are THRA and THRB. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%levothyroxine sodium%" OR LOWER(tradeNames_list) ... | [{'UUID': 'DrugTargetsIndication121923_text_924832', 'drugName': 'Levothyroxine Sodium', 'tradeNames_list': "['Eltroxin', 'Ermeza', 'Euthyrox', 'Evotrox', 'L-thyroxine henning', 'Levo-tLevolet', 'Levothroid', 'Levothyroid', 'Levothyroxine sodium', 'LevoxineLevoxyl', 'Novothyrox', 'Soloxine', 'Synthroid', 'Thyquidity', ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1268 | Q6 | What genes does Treprostinil target when it's used to treat pulmonary hypertension? | When used to treat pulmonary hypertension, the drug Treprostinil targets the gene PTGIR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%treprostinil%" OR LOWER(tradeNames_list) LIKE "%t... | [{'UUID': 'DrugTargetsIndication121923_text_245012', 'drugName': 'Treprostinil', 'tradeNames_list': "['Remodulin', 'Tyvaso', 'Tyvaso dpi']", 'syns_list': "['15-AU-81', '15AU81', 'L-606', 'LRX -15', 'LRX-15', 'Rumodolin', 'TreprostinilTresprostinil', 'UT-15', 'Uniprost']", 'target': 'ENSG00000160013', 'approvedSymbol': ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1475 | Q6 | What genes does Amlodipine Benzoate target when it's used to treat coronary artery disease? | When used to treat coronary artery disease, the drug Amlodipine Benzoate targets the genes CACNA1C, CACNA1S, CACNA1D, and CACNA1F. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%amlodipine benzoate%" OR LOWER(tradeNames_list) L... | [{'UUID': 'DrugTargetsIndication121923_text_1044029', 'drugName': 'Amlodipine Benzoate', 'tradeNames_list': "['Katerzia']", 'syns_list': "['Amlodipine benzoate']", 'target': 'ENSG00000151067', 'approvedSymbol': 'CACNA1C', 'approvedName': 'calcium voltage-gated channel subunit alpha1 C', 'mesh_heading': 'Coronary Artery... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1502 | Q6 | What genes does Gemcitabine Hydrochloride target when it's used to treat pancreatic carcinoma? | When used to treat pancreatic carcinoma, the drug Gemcitabine Hydrochloride targets the genes POLA1, POLD4, POLD3, POLD1, POLD2, POLE, POLA2, PRIM1, PRIM2, POLE2, POLE3, RRM1, RRM2B, and RRM2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%gemcitabine hydrochloride%" OR LOWER(tradeNames_l... | [{'UUID': 'DrugTargetsIndication121923_text_756070', 'drugName': 'Gemcitabine Hydrochloride', 'tradeNames_list': "['Gemcitabine hydrochloride', 'Gemzar', 'Infugem']", 'syns_list': "['Gemcitabine (as hydrochloride)', 'Gemcitabine hclGemcitabine hydrochloride', 'Gemzar', 'LY-188011LY-188011 HYDROCHLORIDE', 'LY188011 HYDR... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.370 | Q6 | What genes does Everolimus target when it's used to treat breast neoplasm? | When used to treat breast neoplasm, the drug Everolimus targets the gene FKBP1A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%everolimus%" OR LOWER(tradeNames_list) LIKE "%eve... | [{'UUID': 'DrugTargetsIndication121923_text_1088734', 'drugName': 'Everolimus', 'tradeNames_list': "['Afinitor', 'Afinitor disperz', 'Certican', 'Votubia', 'Zortress']", 'syns_list': "['40-o-(2-hydroxyethyl)-rapamycin', 'Everolimus', 'RAD 666', 'RAD-001RAD-666', 'RAD001', 'SDZ-RAD', 'Sdz rad']", 'target': 'ENSG00000088... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1009 | Q6 | What genes does Prednisone target when it's used to treat type 2 diabetes mellitus? | Prednisone has not been approved by the FDA as a treatment for type 2 diabetes mellitus, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%prednisone%" OR LOWER(tradeNames_list) LIKE "%pre... | [{'UUID': 'DrugTargetsIndication121923_text_218724', 'drugName': 'Prednisone', 'tradeNames_list': "['Cortan', 'Cortancyl', 'Decortisyl', 'Delta-dome', 'Deltasone', 'FernisoneLiquid pred', 'Lodotra', 'Meticorten', 'Orasone', 'Paracort', 'Prednicen-mPrednisone', 'Prednisone intensol', 'Rayos', 'Servisone', 'Sterapred']",... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1239 | Q6 | What genes does Bromfenac Sodium target when it's used to treat Ocular pain? | When used to treat Ocular pain, the drug Bromfenac Sodium targets the genes PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%bromfenac sodium%" OR LOWER(tradeNames_list) LIKE... | [{'UUID': 'DrugTargetsIndication121923_text_842557', 'drugName': 'Bromfenac Sodium', 'tradeNames_list': "['Bromday', 'Bromfenac sodium', 'Bromsite', 'Prolensa', 'Xibrom']", 'syns_list': "['AHR-10282B', 'Bromfenac monosodium saltBromfenac monosodium salt sesquihydrate', 'Bromfenac sodiumBromfenac sodium anhydrous', 'Bro... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.595 | Q6 | What genes does Fenofibrate target when it's used to treat diabetic nephropathy? | Fenofibrate has not been approved by the FDA as a treatment for diabetic nephropathy, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is PPARA. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fenofibrate%" OR LOWER(tradeNames_list) LIKE "%fe... | [{'UUID': 'DrugTargetsIndication121923_text_244062', 'drugName': 'Fenofibrate', 'tradeNames_list': "['Antara', 'Antara (micronized)', 'Fenofibrate', 'Fenofibrate (micronized)Fenogal', 'Fenoglide', 'Lipantil', 'Lipantil micro 200Lipantil micro 267', 'Lipantil micro 67', 'Lipidil', 'LipofenSupralip 160', 'Tricor', 'Trico... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.728 | Q6 | What genes does Ephedrine Sulfate target when it's used to treat hypotension? | When used to treat hypotension, the drug Ephedrine Sulfate targets the genes ADRA1A, ADRB2, ADRB1, ADRB3, ADRA1D, ADRA1B, ADRA2A, ADRA2C, and ADRA2B. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ephedrine sulfate%" OR LOWER(tradeNames_list) LIK... | [{'UUID': 'DrugTargetsIndication121923_text_418287', 'drugName': 'Ephedrine Sulfate', 'tradeNames_list': "['Akovaz', 'Corphedra', 'Emerphed', 'Expansyl', 'Franol plus', 'Franol-plusIsofedrol']", 'syns_list': "['Ephedrine sulfate', 'Ephedrine sulphate', 'Ephedrini sulfas']", 'target': 'ENSG00000043591', 'approvedSymbol'... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.486 | Q6 | What genes does Tretinoin target when it's used to treat neoplasm? | When used to treat neoplasm, the drug Tretinoin targets the genes RARG, RARB, and RARA. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%tretinoin%" OR LOWER(tradeNames_list) LIKE "%tret... | [{'UUID': 'DrugTargetsIndication121923_text_1053600', 'drugName': 'Tretinoin', 'tradeNames_list': "['Acticin', 'Altreno', 'Atralin', 'Avita', 'Renova', 'Retin-a', 'Retin-a microRetin-a-micro', 'Tretin-X', 'Tretinoin', 'Vesanoid']", 'syns_list': "['Aberel', 'All-trans retinoic acid', 'All-trans-retinoic acid', 'EudynaKe... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.573 | Q6 | What genes does Maralixibat Chloride target when it's used to treat Alagille syndrome? | When used to treat Alagille syndrome, the drug Maralixibat Chloride targets the gene SLC10A2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%maralixibat chloride%" OR LOWER(tradeNames_list) ... | [{'UUID': 'DrugTargetsIndication121923_text_992697', 'drugName': 'Maralixibat Chloride', 'tradeNames_list': "['Livmarli']", 'syns_list': "['LUM-001', 'LUM001', 'Lopixibat chloride', 'Maralixibat chloride']", 'target': 'ENSG00000125255', 'approvedSymbol': 'SLC10A2', 'approvedName': 'solute carrier family 10 member 2', '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.74 | Q6 | What genes does Fluticasone Furoate target when it's used to treat Rhinitis, Allergic, Perennial? | When used to treat Rhinitis, Allergic, Perennial, the drug Fluticasone Furoate targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fluticasone furoate%" OR LOWER(tradeNames_list) L... | [{'UUID': 'DrugTargetsIndication121923_text_225662', 'drugName': 'Fluticasone Furoate', 'tradeNames_list': "['Arnuity ellipta', 'Avamys', 'Flonase sensimist allergy reliefRelvar ellipta', 'Trelegy ellipta', 'Veramyst']", 'syns_list': "['Allermist', 'Ennhale', 'Fluticasone furoate', 'Furamist', 'GSK 685 698GSK-685968', ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.635 | Q6 | What genes does Carbinoxamine Maleate target when it's used to treat seasonal allergic rhinitis? | When used to treat seasonal allergic rhinitis, the drug Carbinoxamine Maleate targets the gene HRH1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%carbinoxamine maleate%" OR LOWER(tradeNames_list)... | [{'UUID': 'DrugTargetsIndication121923_text_455848', 'drugName': 'Carbinoxamine Maleate', 'tradeNames_list': "['Carbinoxamine maleate', 'Clistin', 'Davenol', 'Karbinal er']", 'syns_list': "['Carbinoxamine maleate', 'NSC-62362']", 'target': 'ENSG00000196639', 'approvedSymbol': 'HRH1', 'approvedName': 'histamine receptor... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.262 | Q6 | What genes does Dasatinib target when it's used to treat lung cancer? | Dasatinib has not been approved by the FDA as a treatment for lung cancer, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are ABL1, BCR, HCK, SRC, LYN, KIT, PDGFRB, EPHA2, FRK, FYN, LCK, YES1, BLK, FGR, and SRMS. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dasatinib%" OR LOWER(tradeNames_list) LIKE "%dasa... | [{'UUID': 'DrugTargetsIndication121923_text_713586', 'drugName': 'Dasatinib', 'tradeNames_list': "['Dasatinib', 'Sprycel']", 'syns_list': "['BMS-354825', 'BMS-354825 HYDRATE', 'BMS-354825-03', 'DasatinibDasatinib anhydrous', 'Dasatinib hydrate', 'Dasatinib monohydrateNSC-759877']", 'target': 'ENSG00000097007', 'approve... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.52 | Q6 | What genes does Methotrexate target when it's used to treat cancer? | When used to treat cancer, the drug Methotrexate targets the gene DHFR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%methotrexate%" OR LOWER(tradeNames_list) LIKE "%m... | [{'UUID': 'DrugTargetsIndication121923_text_1058890', 'drugName': 'Methotrexate', 'tradeNames_list': "['Amethopterin', 'Ebetrex', 'Emtexate high-pot', 'Emtexate pf', 'FolexMaxtrex', 'Methotrexate', 'Metoject', 'Mexate', 'Otrexup', 'Otrexup pfsRasuvo', 'Reditrex', 'Rheumatrex', 'Trexall', 'Zlatal']", 'syns_list': "['(r)... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.201 | Q6 | What genes does Alpelisib target when it's used to treat gastric cancer? | Alpelisib has not been approved by the FDA as a treatment for gastric cancer, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is PIK3CA. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%alpelisib%" OR LOWER(tradeNames_list) LIKE "%alpe... | [{'UUID': 'DrugTargetsIndication121923_text_939617', 'drugName': 'Alpelisib', 'tradeNames_list': "['Piqray', 'Vijoice']", 'syns_list': "['Alpelisib', 'BYL-719', 'BYL719', 'Byl-719', 'NVP-BYL719', 'Vijoice']", 'target': 'ENSG00000121879', 'approvedSymbol': 'PIK3CA', 'approvedName': 'phosphatidylinositol-4,5-bisphosphate... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.432 | Q6 | What genes does Sirolimus target when it's used to treat hemangioendothelioma? | Sirolimus has not been approved by the FDA as a treatment for hemangioendothelioma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is FKBP1A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%sirolimus%" OR LOWER(tradeNames_list) LIKE "%siro... | [{'UUID': 'DrugTargetsIndication121923_text_1084538', 'drugName': 'Sirolimus', 'tradeNames_list': "['Fyarro', 'Hyftor', 'Rapamune', 'Sirolimus']", 'syns_list': "['AY-22989', 'Fyarro', 'Hyftor', 'L04AA10', 'NSC-226080', 'Npc-12g', 'RapalimusRapamycin', 'SM-88 COMPONENT SIROLIMUS', 'Sirolimus', 'WY-090217']", 'target': '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1563 | Q6 | What genes does Ketorolac Tromethamine target when it's used to treat inflammation? | When used to treat inflammation, the drug Ketorolac Tromethamine targets the genes PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ketorolac tromethamine%" OR LOWER(tradeNames_list... | [{'UUID': 'DrugTargetsIndication121923_text_841847', 'drugName': 'Ketorolac Tromethamine', 'tradeNames_list': "['Acular', 'Acular ls', 'Acular preservative free', 'AcuvailKetorolac tromethamine', 'Sprix', 'Toradol']", 'syns_list': "['Dolac', 'Ketorolac trometamol', 'Ketorolac tromethamine', 'LixidolNSC-758637', 'Tarasy... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.336 | Q6 | What genes does Doxycycline target when it's used to treat Marfan syndrome? | Doxycycline has not been approved by the FDA as a treatment for Marfan syndrome, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are MMP7, MMP1, MMP13, and MMP8. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%doxycycline%" OR LOWER(tradeNames_list) LIKE "%do... | [{'UUID': 'DrugTargetsIndication121923_text_1038193', 'drugName': 'Doxycycline', 'tradeNames_list': "['Doxychel', 'Doxycycline', 'Monodox', 'Oracea', 'Vibramycin']", 'syns_list': "['Doxirobe', 'Doxycycline', 'Doxycycline monohydrate', 'Doxylin', 'GS-3065Supracyclin', 'Xyrosa']", 'target': 'ENSG00000137673', 'approvedSy... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1557 | Q6 | What genes does Clozapine target when it's used to treat anxiety? | Clozapine has not been approved by the FDA as a treatment for anxiety, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are DRD2 and HTR2A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%clozapine%" OR LOWER(tradeNames_list) LIKE "%cloz... | [{'UUID': 'DrugTargetsIndication121923_text_157982', 'drugName': 'Clozapine', 'tradeNames_list': "['Clozapine', 'Clozaril', 'Fazaclo', 'Fazaclo odt', 'Versacloz', 'Zaponex']", 'syns_list': "['Clozapine', 'Clozapine (caraco)', 'Clozapine (clozaril)Clozapine (fazaclo)', 'Clozapine (ivax)', 'Clozapine (mylan)Clozapine (te... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1539 | Q6 | What genes does Nitric Oxide target when it's used to treat respiratory system disease? | When used to treat respiratory system disease, the drug Nitric Oxide targets the genes GUCY1B1, GUCY1B2, GUCY1A2, and GUCY1A1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%nitric oxide%" OR LOWER(tradeNames_list) LIKE "%n... | [{'UUID': 'DrugTargetsIndication121923_text_974422', 'drugName': 'Nitric Oxide', 'tradeNames_list': "['Genosyl', 'Inomax']", 'syns_list': "['Amidogen, oxo-', 'Inovent', 'Nitric oxide', 'Nitric oxide trimerNitrogen oxide (no)', 'Nitrosyl radical', 'OHM-11771']", 'target': 'ENSG00000061918', 'approvedSymbol': 'GUCY1B1', ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.426 | Q6 | What genes does Ixazomib target when it's used to treat lymphoma? | Ixazomib has not been approved by the FDA as a treatment for lymphoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are PSMD1, PSMB2, PSMB1, PSMB5, PSMB8, PSMB9, PSMB6, PSMD14, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMA7, PSMA8, PSMB10, PSMB11, PSMB3, PSMB... | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ixazomib%" OR LOWER(tradeNames_list) LIKE "%ixazo... | [{'UUID': 'DrugTargetsIndication121923_text_247143', 'drugName': 'Ixazomib', 'tradeNames_list': "['Ninlaro']", 'syns_list': "['Ixazomib', 'MLN-2238', 'MLN-9708 FREE BASE', 'MLN2238']", 'target': 'ENSG00000126067', 'approvedSymbol': 'PSMB2', 'approvedName': 'proteasome 20S subunit beta 2', 'mesh_heading': 'Lymphoma, Fol... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.637 | Q6 | What genes does Temsirolimus target when it's used to treat Uterine Carcinosarcoma? | Temsirolimus has not been approved by the FDA as a treatment for Uterine Carcinosarcoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is FKBP1A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%temsirolimus%" OR LOWER(tradeNames_list) LIKE "%t... | [{'UUID': 'DrugTargetsIndication121923_text_1091064', 'drugName': 'Temsirolimus', 'tradeNames_list': "['Torisel']", 'syns_list': "['CCI-779', 'Temsirolimus']", 'target': 'ENSG00000088832', 'approvedSymbol': 'FKBP1A', 'approvedName': 'FKBP prolyl isomerase 1A', 'mesh_heading': 'Retroviridae Infections', 'efo_term': 'Ute... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.941 | Q6 | What genes does Fludarabine Phosphate target when it's used to treat anaplastic large cell lymphoma? | Fludarabine Phosphate has not been approved by the FDA as a treatment for anaplastic large cell lymphoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are POLA1, POLD4, POLD3, POLD1, POLD2, POLE, POLA2, PRIM1, PRIM2, POLE2, POLE3, RRM1, RRM2B, and RRM2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fludarabine phosphate%" OR LOWER(tradeNames_list)... | [{'UUID': 'DrugTargetsIndication121923_text_754561', 'drugName': 'Fludarabine Phosphate', 'tradeNames_list': "['Fludara', 'Fludarabine phosphate', 'Oforta']", 'syns_list': '[\'2-f-ara-amp\', \'2-f-araa\', \'2-fluoro ara-a\', \'2-fluorovidarabineFludarabine\', "Fludarabine 5\'-monophosphateFludarabine monophosphateFluda... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.993 | Q6 | What genes does Tolvaptan target when it's used to treat cardiovascular disease? | When used to treat cardiovascular disease, the drug Tolvaptan targets the gene AVPR2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%tolvaptan%" OR LOWER(tradeNames_list) LIKE "%tolv... | [{'UUID': 'DrugTargetsIndication121923_text_695169', 'drugName': 'Tolvaptan', 'tradeNames_list': "['Jinarc', 'Jynarque', 'Samsca']", 'syns_list': "['OPC-41061', 'OPC-41061(TOLVAPTAN)', 'Tolvaptan']", 'target': 'ENSG00000126895', 'approvedSymbol': 'AVPR2', 'approvedName': 'arginine vasopressin receptor 2', 'mesh_heading... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.868 | Q6 | What genes does Cannabidiol target when it's used to treat insomnia? | Cannabidiol has not been approved by the FDA as a treatment for insomnia, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is CNR1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%cannabidiol%" OR LOWER(tradeNames_list) LIKE "%ca... | [{'UUID': 'DrugTargetsIndication121923_text_1073728', 'drugName': 'Cannabidiol', 'tradeNames_list': "['Epidiolex']", 'syns_list': "['(-)-cannabidiol', '(-)-cbd', '(-)-trans-cannabidiol.delta.1(2)-trans-cannabidiol', 'BTX-1204', 'BTX-1503', 'CBD', 'CannabidiolCannabidiol solution', 'Cardiolrx', 'GWP-42003', 'GWP-42003-P... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1951 | Q6 | What genes does Revefenacin target when it's used to treat Airway obstruction? | When used to treat Airway obstruction, the drug Revefenacin targets the gene CHRM3. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%revefenacin%" OR LOWER(tradeNames_list) LIKE "%re... | [{'UUID': 'DrugTargetsIndication121923_text_857810', 'drugName': 'Revefenacin', 'tradeNames_list': "['Yupelri']", 'syns_list': "['GSK-1160724', 'GSK1160724', 'Revefenacin', 'TD-4208']", 'target': 'ENSG00000133019', 'approvedSymbol': 'CHRM3', 'approvedName': 'cholinergic receptor muscarinic 3', 'mesh_heading': 'Lung Dis... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.558 | Q6 | What genes does Tivozanib Hydrochloride target when it's used to treat breast cancer? | Tivozanib Hydrochloride has not been approved by the FDA as a treatment for breast cancer, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are KDR, FLT1, KIT, FLT4, and PDGFRB. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%tivozanib hydrochloride%" OR LOWER(tradeNames_lis... | [{'UUID': 'DrugTargetsIndication121923_text_682893', 'drugName': 'Tivozanib Hydrochloride', 'tradeNames_list': "['Fotivda']", 'syns_list': "['AV-951', 'Tivozanib hydrochloride', 'Tivozanib hydrochloride monohydrate']", 'target': 'ENSG00000102755', 'approvedSymbol': 'FLT1', 'approvedName': 'fms related receptor tyrosine... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.433 | Q6 | What genes does Fluocinolone Acetonide target when it's used to treat eye inflammation? | When used to treat eye inflammation, the drug Fluocinolone Acetonide targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fluocinolone acetonide%" OR LOWER(tradeNames_list... | [{'UUID': 'DrugTargetsIndication121923_text_242238', 'drugName': 'Fluocinolone Acetonide', 'tradeNames_list': "['Capex', 'Derma-smoothe/fs', 'Dermotic', 'Fluocet', 'Fluocinolone acetonideFluonid', 'Fluotrex', 'Fs shampoo', 'Iluvien', 'Retisert', 'SynalarSynalar fte', 'Synalar-c', 'Synalar-hp', 'Synalar-n', 'Synandone',... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1777 | Q6 | What genes does Tasimelteon target when it's used to treat Chromosomal anomaly? | When used to treat Chromosomal anomaly, the drug Tasimelteon targets the genes MTNR1A and MTNR1B. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%tasimelteon%" OR LOWER(tradeNames_list) LIKE "%ta... | [{'UUID': 'DrugTargetsIndication121923_text_1094715', 'drugName': 'Tasimelteon', 'tradeNames_list': "['Hetlioz', 'Hetlioz lq']", 'syns_list': "['BMS-214,778', 'BMS-214778', 'Tasimelteon', 'VEC-162']", 'target': 'ENSG00000168412', 'approvedSymbol': 'MTNR1A', 'approvedName': 'melatonin receptor 1A', 'mesh_heading': 'Smit... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1834 | Q6 | What genes does Naloxone target when it's used to treat drug dependence? | Naloxone has not been approved by the FDA as a treatment for drug dependence, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are OPRM1, OPRK1, and OPRD1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%naloxone%" OR LOWER(tradeNames_list) LIKE "%nalox... | [{'UUID': 'DrugTargetsIndication121923_text_791499', 'drugName': 'Naloxone', 'tradeNames_list': "['Nalone', 'Narcan', 'Narcanti']", 'syns_list': "['Dbl naloxone', 'NSC-70413', 'Naloxone', 'Suboxone']", 'target': 'ENSG00000112038', 'approvedSymbol': 'OPRM1', 'approvedName': 'opioid receptor mu 1', 'mesh_heading': 'Subst... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1977 | Q6 | What genes does Azacitidine target when it's used to treat refractory anemia with excess blasts? | When used to treat refractory anemia with excess blasts, the drug Azacitidine targets the genes DNMT1 and DNMT3A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%azacitidine%" OR LOWER(tradeNames_list) LIKE "%az... | [{'UUID': 'DrugTargetsIndication121923_text_1191980', 'drugName': 'Azacitidine', 'tradeNames_list': "['Azacitidine', 'Onureg', 'Vidaza']", 'syns_list': "['5-azacitidine', 'Azacitidine', 'Ladakamycin', 'NSC-102816', 'U-18,496U-18496', 'Vidaza']", 'target': 'ENSG00000130816', 'approvedSymbol': 'DNMT1', 'approvedName': 'D... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1506 | Q6 | What genes does Everolimus target when it's used to treat cancer? | When used to treat cancer, the drug Everolimus targets the gene FKBP1A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%everolimus%" OR LOWER(tradeNames_list) LIKE "%eve... | [{'UUID': 'DrugTargetsIndication121923_text_1087385', 'drugName': 'Everolimus', 'tradeNames_list': "['Afinitor', 'Afinitor disperz', 'Certican', 'Votubia', 'Zortress']", 'syns_list': "['40-o-(2-hydroxyethyl)-rapamycin', 'Everolimus', 'RAD 666', 'RAD-001RAD-666', 'RAD001', 'SDZ-RAD', 'Sdz rad']", 'target': 'ENSG00000088... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1622 | Q6 | What genes does Mometasone Furoate target when it's used to treat Nasal polyposis? | When used to treat Nasal polyposis, the drug Mometasone Furoate targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%mometasone furoate%" OR LOWER(tradeNames_list) LI... | [{'UUID': 'DrugTargetsIndication121923_text_242038', 'drugName': 'Mometasone Furoate', 'tradeNames_list': "['Asmanex', 'Asmanex hfa', 'Asmanex twisthaler', 'EloconMometasone furoate', 'Nasonex', 'Nasonex 24hr allergy', 'Sinuva']", 'syns_list': "['LAS-41002', 'LAS41002', 'LYR-210', 'LYR210', 'Lyr-210', 'MometasoneMometa... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.404 | Q6 | What genes does Roflumilast target when it's used to treat chronic bronchitis? | When used to treat chronic bronchitis, the drug Roflumilast targets the genes PDE4A, PDE4D, PDE4B, and PDE4C. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%roflumilast%" OR LOWER(tradeNames_list) LIKE "%ro... | [{'UUID': 'DrugTargetsIndication121923_text_695491', 'drugName': 'Roflumilast', 'tradeNames_list': "['Daliresp', 'Daxas', 'Zoryve']", 'syns_list': "['Arq-151', 'B-9302-107', 'B9302-107', 'BY-217', 'BY217', 'BYK-20869BYK20869', 'Roflumilast', 'Zoryve']", 'target': 'ENSG00000065989', 'approvedSymbol': 'PDE4A', 'approvedN... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1791 | Q6 | What genes does Loxapine target when it's used to treat psychosis? | When used to treat psychosis, the drug Loxapine targets the genes HTR2C, DRD2, DRD3, DRD4, and HTR2A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%loxapine%" OR LOWER(tradeNames_list) LIKE "%loxap... | [{'UUID': 'DrugTargetsIndication121923_text_149112', 'drugName': 'Loxapine', 'tradeNames_list': "['Adasuve', 'Loxitane intramuscular [as hydrochloride]Loxitane-c oral suspension [as hydrochloride]']", 'syns_list': "['CL 62,362', 'CL-62362', 'Loxapac', 'Loxapine', 'Loxitane', 'SUM 3170SUM-3170']", 'target': 'ENSG0000014... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.195 | Q6 | What genes does Dexamethasone target when it's used to treat seasonal allergic rhinitis? | When used to treat seasonal allergic rhinitis, the drug Dexamethasone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dexamethasone%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_227762', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1281 | Q6 | What genes does Panobinostat target when it's used to treat cancer? | When used to treat cancer, the drug Panobinostat targets the genes HDAC1, HDAC3, HDAC6, HDAC2, HDAC5, HDAC7, HDAC8, HDAC11, HDAC4, HDAC9, and HDAC10. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%panobinostat%" OR LOWER(tradeNames_list) LIKE "%p... | [{'UUID': 'DrugTargetsIndication121923_text_1080688', 'drugName': 'Panobinostat', 'tradeNames_list': "['Farydak']", 'syns_list': "['LBH-589', 'LBH589', 'Panobinostat', 'Panobinostat hydrate']", 'target': 'ENSG00000116478', 'approvedSymbol': 'HDAC1', 'approvedName': 'histone deacetylase 1', 'mesh_heading': 'Neoplasms', ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1381 | Q6 | What genes does Cannabidiol target when it's used to treat epilepsy? | When used to treat epilepsy, the drug Cannabidiol targets the gene CNR1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%cannabidiol%" OR LOWER(tradeNames_list) LIKE "%ca... | [{'UUID': 'DrugTargetsIndication121923_text_1074784', 'drugName': 'Cannabidiol', 'tradeNames_list': "['Epidiolex']", 'syns_list': "['(-)-cannabidiol', '(-)-cbd', '(-)-trans-cannabidiol.delta.1(2)-trans-cannabidiol', 'BTX-1204', 'BTX-1503', 'CBD', 'CannabidiolCannabidiol solution', 'Cardiolrx', 'GWP-42003', 'GWP-42003-P... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.677 | Q6 | What genes does Dexamethasone target when it's used to treat pneumonia? | When used to treat pneumonia, the drug Dexamethasone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dexamethasone%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_228042', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.795 | Q6 | What genes does Tafamidis target when it's used to treat amyloidosis? | When used to treat amyloidosis, the drug Tafamidis targets the gene TTR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%tafamidis%" OR LOWER(tradeNames_list) LIKE "%tafa... | [{'UUID': 'DrugTargetsIndication121923_text_1097605', 'drugName': 'Tafamidis', 'tradeNames_list': "['Vyndamax', 'Vyndaqel']", 'syns_list': "['FX-1005', 'FX-1006', 'FX1006', 'Tafamidis']", 'target': 'ENSG00000118271', 'approvedSymbol': 'TTR', 'approvedName': 'transthyretin', 'mesh_heading': 'Amyloidosis, Familial', 'efo... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1463 | Q6 | What genes does Rolapitant Hydrochloride target when it's used to treat Chemotherapy-induced nausea and vomiting? | When used to treat Chemotherapy-induced nausea and vomiting, the drug Rolapitant Hydrochloride targets the gene TACR1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%rolapitant hydrochloride%" OR LOWER(tradeNames_li... | [{'UUID': 'DrugTargetsIndication121923_text_1073115', 'drugName': 'Rolapitant Hydrochloride', 'tradeNames_list': "['Varubi']", 'syns_list': "['Rolapitant hcl h20', 'Rolapitant hydrochlorideRolapitant hydrochloride monohydrate', 'SCH-619734', 'SCH619734']", 'target': 'ENSG00000115353', 'approvedSymbol': 'TACR1', 'approv... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1457 | Q6 | What genes does Prednisone target when it's used to treat pemphigus vulgaris? | When used to treat pemphigus vulgaris, the drug Prednisone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%prednisone%" OR LOWER(tradeNames_list) LIKE "%pre... | [{'UUID': 'DrugTargetsIndication121923_text_218686', 'drugName': 'Prednisone', 'tradeNames_list': "['Cortan', 'Cortancyl', 'Decortisyl', 'Delta-dome', 'Deltasone', 'FernisoneLiquid pred', 'Lodotra', 'Meticorten', 'Orasone', 'Paracort', 'Prednicen-mPrednisone', 'Prednisone intensol', 'Rayos', 'Servisone', 'Sterapred']",... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.144 | Q6 | What genes does Carbinoxamine Maleate target when it's used to treat allergic conjunctivitis? | When used to treat allergic conjunctivitis, the drug Carbinoxamine Maleate targets the gene HRH1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%carbinoxamine maleate%" OR LOWER(tradeNames_list)... | [{'UUID': 'DrugTargetsIndication121923_text_455851', 'drugName': 'Carbinoxamine Maleate', 'tradeNames_list': "['Carbinoxamine maleate', 'Clistin', 'Davenol', 'Karbinal er']", 'syns_list': "['Carbinoxamine maleate', 'NSC-62362']", 'target': 'ENSG00000196639', 'approvedSymbol': 'HRH1', 'approvedName': 'histamine receptor... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1188 | Q6 | What genes does Inclisiran Sodium target when it's used to treat atherosclerosis? | When used to treat atherosclerosis, the drug Inclisiran Sodium targets the gene PCSK9. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%inclisiran sodium%" OR LOWER(tradeNames_list) LIK... | [{'UUID': 'DrugTargetsIndication121923_text_993749', 'drugName': 'Inclisiran Sodium', 'tradeNames_list': "['Leqvio']", 'syns_list': "['Inclisiran sodium', 'Leqvio sodium']", 'target': 'ENSG00000169174', 'approvedSymbol': 'PCSK9', 'approvedName': 'proprotein convertase subtilisin/kexin type 9', 'mesh_heading': 'Atherosc... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.3 | Q6 | What genes does Rosuvastatin Calcium target when it's used to treat atherosclerosis? | When used to treat atherosclerosis, the drug Rosuvastatin Calcium targets the gene HMGCR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%rosuvastatin calcium%" OR LOWER(tradeNames_list) ... | [{'UUID': 'DrugTargetsIndication121923_text_1104217', 'drugName': 'Rosuvastatin Calcium', 'tradeNames_list': "['Crestor', 'Ezallor', 'Ezallor sprinkle', 'Rosuvastatin calcium']", 'syns_list': "['Fortius', 'NSC-747274', 'NSC-758930', 'Rostar', 'Rosuvastatin (as calcium)Rosuvastatin calcium', 'Rosuvastatin calcium saltRo... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.743 | Q6 | What genes does Midostaurin target when it's used to treat systemic mastocytosis? | When used to treat systemic mastocytosis, the drug Midostaurin targets the genes KDR, FLT3, KIT, PDGFRB, PDGFRA, PRKCE, PRKCB, PRKD3, PRKCI, PRKCA, PRKCG, PRKCD, PRKCZ, PRKCH, PRKD1, and PRKCQ. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%midostaurin%" OR LOWER(tradeNames_list) LIKE "%mi... | [{'UUID': 'DrugTargetsIndication121923_text_667338', 'drugName': 'Midostaurin', 'tradeNames_list': "['Rydapt']", 'syns_list': "['CGP 41251', 'CGP-41251', 'Midostaurin', 'NSC-656576', 'NVP-PKC412', 'PKC 412PKC-412', 'Pkc-412']", 'target': 'ENSG00000122025', 'approvedSymbol': 'FLT3', 'approvedName': 'fms related receptor... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1871 | Q6 | What genes does Metformin Hydrochloride target when it's used to treat pancreatic carcinoma? | Metformin Hydrochloride has not been approved by the FDA as a treatment for pancreatic carcinoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are MT-ND6, NDUFA10, NDUFS8, MT-ND4L, NDUFA6, MT-ND1, NDUFB6, NDUFA4, NDUFA11, NDUFB7, MT-ND2, NDUFS2, MT-ND5, NDUFA8... | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%metformin hydrochloride%" OR LOWER(tradeNames_lis... | [{'UUID': 'DrugTargetsIndication121923_text_1149678', 'drugName': 'Metformin Hydrochloride', 'tradeNames_list': "['Bolamyn sr', 'Diagemet xl', 'Fortamet', 'Glucamet 500', 'Glucamet 850Glucient sr', 'Glucophage', 'Glucophage sr', 'Glucophage xr', 'GlumetzaGlyformin', 'Janumet', 'Ledermetin', 'Metabet sr', 'Metformin hyd... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1516 | Q6 | What genes does Fenofibrate target when it's used to treat type 2 diabetes mellitus? | When used to treat type 2 diabetes mellitus, the drug Fenofibrate targets the gene PPARA. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fenofibrate%" OR LOWER(tradeNames_list) LIKE "%fe... | [{'UUID': 'DrugTargetsIndication121923_text_243843', 'drugName': 'Fenofibric Acid', 'tradeNames_list': "['Fenocor-67', 'Fenogal', 'Fibricor', 'Lipanthyl', 'Lipofen', 'LofibraSupralip', 'Trilipix']", 'syns_list': "['Fenofibrate free acid', 'Fenofibrate related compound bFenofibric acid', 'LF-153', 'NSC-281318', 'Proceto... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.343 | Q6 | What genes does Choline Fenofibrate target when it's used to treat Combined hyperlipidemia? | Choline Fenofibrate has not been approved by the FDA as a treatment for Combined hyperlipidemia, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is PPARA. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%choline fenofibrate%" OR LOWER(tradeNames_list) L... | [{'UUID': 'DrugTargetsIndication121923_text_243906', 'drugName': 'Choline Fenofibrate', 'tradeNames_list': "['Trilipix']", 'syns_list': "['ABT-335', 'Choline fenofibrate', 'Fenofibric acid choline salt']", 'target': 'ENSG00000186951', 'approvedSymbol': 'PPARA', 'approvedName': 'peroxisome proliferator activated recepto... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.626 | Q6 | What genes does Glucagon target when it's used to treat familial hyperinsulinism? | Glucagon has not been approved by the FDA as a treatment for familial hyperinsulinism, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is GCGR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%glucagon%" OR LOWER(tradeNames_list) LIKE "%gluca... | [{'UUID': 'DrugTargetsIndication121923_text_968330', 'drugName': 'Glucagon', 'tradeNames_list': "['Baqsimi', 'Glucagen Hypokit', 'Glucagon', 'Glucagon Emergency KitGvoke hypopen', 'Gvoke pfs']", 'syns_list': "['Glucagon', 'Glucagon recombinant']", 'target': 'ENSG00000215644', 'approvedSymbol': 'GCGR', 'approvedName': '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.484 | Q6 | What genes does Lubiprostone target when it's used to treat constipation disorder? | When used to treat constipation disorder, the drug Lubiprostone targets the gene CLCN2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lubiprostone%" OR LOWER(tradeNames_list) LIKE "%l... | [{'UUID': 'DrugTargetsIndication121923_text_1193412', 'drugName': 'Lubiprostone', 'tradeNames_list': "['Amitiza']", 'syns_list': "['Lubiprostone', 'RU-0211']", 'target': 'ENSG00000114859', 'approvedSymbol': 'CLCN2', 'approvedName': 'chloride voltage-gated channel 2', 'mesh_heading': 'Constipation', 'efo_term': 'constip... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.532 | Q6 | What genes does Aspirin target when it's used to treat osteoarthritis? | Aspirin has not been approved by the FDA as a treatment for osteoarthritis, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%aspirin%" OR LOWER(tradeNames_list) LIKE "%aspiri... | [{'UUID': 'DrugTargetsIndication121923_text_834414', 'drugName': 'Aspirin', 'tradeNames_list': "['8-hour bayer', 'Acetosalic Acid', 'Acetylsalic acidAcetylsalicylic Acid', 'Alka rapid', 'Anadin all night', 'Angettes 75Aspirin', 'Aspro clr', 'Bayer extra strength aspirin for migraine painDanamep', 'Disprin cv', 'Disprin... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.268 | Q6 | What genes does Estradiol Acetate target when it's used to treat Atrophy? | When used to treat Atrophy, the drug Estradiol Acetate targets the gene ESR1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%estradiol acetate%" OR LOWER(tradeNames_list) LIK... | [{'UUID': 'DrugTargetsIndication121923_text_823878', 'drugName': 'Estradiol Acetate', 'tradeNames_list': "['Femring', 'Femtrace']", 'syns_list': "['E3A', 'ESTRADIOL-3-ACETATE', 'Estradiol 3-acetate', 'Estradiol acetate']", 'target': 'ENSG00000091831', 'approvedSymbol': 'ESR1', 'approvedName': 'estrogen receptor 1', 'me... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1390 | Q6 | What genes does Prednisone target when it's used to treat ankylosing spondylitis? | When used to treat ankylosing spondylitis, the drug Prednisone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%prednisone%" OR LOWER(tradeNames_list) LIKE "%pre... | [{'UUID': 'DrugTargetsIndication121923_text_218681', 'drugName': 'Prednisone', 'tradeNames_list': "['Cortan', 'Cortancyl', 'Decortisyl', 'Delta-dome', 'Deltasone', 'FernisoneLiquid pred', 'Lodotra', 'Meticorten', 'Orasone', 'Paracort', 'Prednicen-mPrednisone', 'Prednisone intensol', 'Rayos', 'Servisone', 'Sterapred']",... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.681 | Q6 | What genes does Dutetrabenazine target when it's used to treat chorea? | When used to treat chorea, the drug Dutetrabenazine targets the gene SLC18A2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dutetrabenazine%" OR LOWER(tradeNames_list) LIKE ... | [{'UUID': 'DrugTargetsIndication121923_text_938616', 'drugName': 'Dutetrabenazine', 'tradeNames_list': "['Austedo']", 'syns_list': "['Deutetrabenazine', 'Dutetrabenazine', 'SD-809']", 'target': 'ENSG00000165646', 'approvedSymbol': 'SLC18A2', 'approvedName': 'solute carrier family 18 member A2', 'mesh_heading': 'Chorea'... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.492 | Q6 | What genes does Diclofenac target when it's used to treat pain? | When used to treat pain, the drug Diclofenac targets the genes PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%diclofenac%" OR LOWER(tradeNames_list) LIKE "%dic... | [{'UUID': 'DrugTargetsIndication121923_text_836811', 'drugName': 'Diclofenac Sodium', 'tradeNames_list': "['Acoflam', 'Acoflam ret', 'Acoflam sr', 'Arthronac', 'Arthrotec 50Arthrotec 75', 'Closteril 100', 'Defanac', 'Defanac retard', 'Defanac srDexomon ret', 'Dexomon sr', 'Diclofenac sodium', 'DicloflexDicloflex ret', ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.445 | Q6 | What genes does Isotretinoin target when it's used to treat acne? | When used to treat acne, the drug Isotretinoin targets the genes RARG, RARB, and RARA. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%isotretinoin%" OR LOWER(tradeNames_list) LIKE "%i... | [{'UUID': 'DrugTargetsIndication121923_text_1054015', 'drugName': 'Isotretinoin', 'tradeNames_list': "['Absorica', 'Absorica ld', 'Accutane', 'Amnesteem', 'Claravis', 'IsotrexMyorisan', 'Roaccutane', 'Sotret', 'Zenatane']", 'syns_list': "['13 Cis-Retinoic Acid', '13-cis-retinoic acid', 'Isotretinoin', 'NSC-758156PAT-00... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.274 | Q6 | What genes does Palbociclib target when it's used to treat Hereditary breast and ovarian cancer syndrome? | Palbociclib has not been approved by the FDA as a treatment for Hereditary breast and ovarian cancer syndrome, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are CDK4, CDK6, and CCND1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%palbociclib%" OR LOWER(tradeNames_list) LIKE "%pa... | [{'UUID': 'DrugTargetsIndication121923_text_851546', 'drugName': 'Palbociclib', 'tradeNames_list': "['Ibrance']", 'syns_list': "['PD-0332991', 'Palbociclib']", 'target': 'ENSG00000135446', 'approvedSymbol': 'CDK4', 'approvedName': 'cyclin dependent kinase 4', 'mesh_heading': 'Hereditary Breast and Ovarian Cancer Syndro... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.187 | Q6 | What genes does Erdafitinib target when it's used to treat multiple myeloma? | Erdafitinib has not been approved by the FDA as a treatment for multiple myeloma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are FGFR1, FGFR3, FGFR2, and FGFR4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%erdafitinib%" OR LOWER(tradeNames_list) LIKE "%er... | [{'UUID': 'DrugTargetsIndication121923_text_707169', 'drugName': 'Erdafitinib', 'tradeNames_list': "['Balversa']", 'syns_list': "['Erdafitinib', 'JNJ-42756493', 'Jnj-42756493']", 'target': 'ENSG00000077782', 'approvedSymbol': 'FGFR1', 'approvedName': 'fibroblast growth factor receptor 1', 'mesh_heading': 'Multiple Myel... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.950 | Q6 | What genes does Doxycycline target when it's used to treat aneurysm? | Doxycycline has not been approved by the FDA as a treatment for aneurysm, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are MMP7, MMP1, MMP13, and MMP8. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%doxycycline%" OR LOWER(tradeNames_list) LIKE "%do... | [{'UUID': 'DrugTargetsIndication121923_text_1037957', 'drugName': 'Doxycycline', 'tradeNames_list': "['Doxychel', 'Doxycycline', 'Monodox', 'Oracea', 'Vibramycin']", 'syns_list': "['Doxirobe', 'Doxycycline', 'Doxycycline monohydrate', 'Doxylin', 'GS-3065Supracyclin', 'Xyrosa']", 'target': 'ENSG00000137673', 'approvedSy... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.247 | Q6 | What genes does Prednisone target when it's used to treat seasonal allergic rhinitis? | When used to treat seasonal allergic rhinitis, the drug Prednisone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%prednisone%" OR LOWER(tradeNames_list) LIKE "%pre... | [{'UUID': 'DrugTargetsIndication121923_text_218682', 'drugName': 'Prednisone', 'tradeNames_list': "['Cortan', 'Cortancyl', 'Decortisyl', 'Delta-dome', 'Deltasone', 'FernisoneLiquid pred', 'Lodotra', 'Meticorten', 'Orasone', 'Paracort', 'Prednicen-mPrednisone', 'Prednisone intensol', 'Rayos', 'Servisone', 'Sterapred']",... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1100 | Q6 | What genes does Ixabepilone target when it's used to treat endometrial cancer? | Ixabepilone has not been approved by the FDA as a treatment for endometrial cancer, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are TUBB4B, TUBB1, TUBA3C, TUBA4A, TUBB3, TUBA1A, TUBB4A, TUBB8, TUBB, TUBA1B, TUBA1C, TUBA3E, TUBB2A, TUBB2B, and TUBB6. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ixabepilone%" OR LOWER(tradeNames_list) LIKE "%ix... | [{'UUID': 'DrugTargetsIndication121923_text_85069', 'drugName': 'Ixabepilone', 'tradeNames_list': "['Ixempra', 'Ixempra kit']", 'syns_list': "['Azaepothilone b', 'BMS 247550-01', 'BMS-247550', 'BMS-247550-01Ixabepilone', 'Ixempra', 'NSC-747973']", 'target': 'ENSG00000188229', 'approvedSymbol': 'TUBB4B', 'approvedName':... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1018 | Q6 | What genes does Upadacitinib target when it's used to treat rheumatoid arthritis? | When used to treat rheumatoid arthritis, the drug Upadacitinib targets the genes JAK1, JAK3, TYK2, and JAK2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%upadacitinib%" OR LOWER(tradeNames_list) LIKE "%u... | [{'UUID': 'DrugTargetsIndication121923_text_846833', 'drugName': 'Upadacitinib', 'tradeNames_list': "['Rinvoq']", 'syns_list': "['ABT-494', 'Upadacitinib', 'Upadacitinib anhydrousUpadacitinib hemihydrate', 'Upadacitinib hydrate']", 'target': 'ENSG00000162434', 'approvedSymbol': 'JAK1', 'approvedName': 'Janus kinase 1',... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.590 | Q6 | What genes does Apremilast target when it's used to treat immune system disease? | When used to treat immune system disease, the drug Apremilast targets the genes PDE4A, PDE4D, PDE4B, and PDE4C. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%apremilast%" OR LOWER(tradeNames_list) LIKE "%apr... | [{'UUID': 'DrugTargetsIndication121923_text_696932', 'drugName': 'Apremilast', 'tradeNames_list': "['Otezla']", 'syns_list': "['Apremilast', 'CC-10004', 'CC10004']", 'target': 'ENSG00000065989', 'approvedSymbol': 'PDE4A', 'approvedName': 'phosphodiesterase 4A', 'mesh_heading': 'Immune System Diseases', 'efo_term': 'imm... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1629 | Q6 | What genes does Baricitinib target when it's used to treat immune system disease? | When used to treat immune system disease, the drug Baricitinib targets the genes JAK1 and JAK2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%baricitinib%" OR LOWER(tradeNames_list) LIKE "%ba... | [{'UUID': 'DrugTargetsIndication121923_text_843213', 'drugName': 'Baricitinib', 'tradeNames_list': "['Olumiant']", 'syns_list': "['Baricitinib', 'Baricitinib phosphate', 'Baricitinib phosphate saltINCB-028050', 'INCB028050', 'Incb-28050', 'LY-3009104', 'LY3009104']", 'target': 'ENSG00000162434', 'approvedSymbol': 'JAK1... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.535 | Q6 | What genes does Capsaicin target when it's used to treat sprain? | When used to treat sprain, the drug Capsaicin targets the gene TRPV1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%capsaicin%" OR LOWER(tradeNames_list) LIKE "%caps... | [{'UUID': 'DrugTargetsIndication121923_text_993229', 'drugName': 'Capsaicin', 'tradeNames_list': "['Qutenza', 'Zacin', 'Zostrix', 'Zostrix hp']", 'syns_list': "['ALGRX 4975', 'ALGRX-4975', 'Ausanil', 'Axsain', 'Capsaicin', 'Capzasin-hpCntx-4975', 'Dolenon', 'FEMA NO. 3404', 'Mioton', 'NGX-1998', 'NGX-4010NSC-56353', 'N... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.899 | Q6 | What genes does Dexamethasone target when it's used to treat lymphoma? | When used to treat lymphoma, the drug Dexamethasone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dexamethasone%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_228035', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1483 | Q6 | What genes does Thalidomide target when it's used to treat Crohn's disease? | Thalidomide has not been approved by the FDA as a treatment for Crohn's disease, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are CRBN, DDB1, CUL4A, and RBX1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%thalidomide%" OR LOWER(tradeNames_list) LIKE "%th... | [{'UUID': 'DrugTargetsIndication121923_text_1105111', 'drugName': 'Thalidomide', 'tradeNames_list': "['Talidex', 'Thalomid']", 'syns_list': "['.alpha.-phthalimidoglutarimide', 'Celgene', 'Contergan', 'Distaval', 'K-17Myrin', 'N-phthalylglutamic acid imide', 'NSC-527179', 'NSC-66847Neurosedyn', 'Pantosediv', 'Pharmion',... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1109 | Q6 | What genes does Tirzepatide target when it's used to treat type 2 diabetes mellitus? | When used to treat type 2 diabetes mellitus, the drug Tirzepatide targets the genes GLP1R and GIPR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%tirzepatide%" OR LOWER(tradeNames_list) LIKE "%ti... | [{'UUID': 'DrugTargetsIndication121923_text_1045731', 'drugName': 'Tirzepatide', 'tradeNames_list': "['Mounjaro']", 'syns_list': "['LY-3298176', 'LY3298176', 'Ly3298176', 'Mounjaro', 'Tirzepatide']", 'target': 'ENSG00000112164', 'approvedSymbol': 'GLP1R', 'approvedName': 'glucagon like peptide 1 receptor', 'mesh_headin... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.421 | Q6 | What genes does Risdiplam target when it's used to treat spinal muscular atrophy? | When used to treat spinal muscular atrophy, the drug Risdiplam targets the gene SMN2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%risdiplam%" OR LOWER(tradeNames_list) LIKE "%risd... | [{'UUID': 'DrugTargetsIndication121923_text_1072735', 'drugName': 'Risdiplam', 'tradeNames_list': "['Evrysdi']", 'syns_list': "['RG-7916', 'RG7916', 'RO-7034067', 'RO7034067', 'Risdiplam']", 'target': 'ENSG00000205571', 'approvedSymbol': 'SMN2', 'approvedName': 'survival of motor neuron 2, centromeric', 'mesh_heading':... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.277 | Q6 | What genes does Methotrexate target when it's used to treat breast neoplasm? | When used to treat breast neoplasm, the drug Methotrexate targets the gene DHFR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%methotrexate%" OR LOWER(tradeNames_list) LIKE "%m... | [{'UUID': 'DrugTargetsIndication121923_text_1056957', 'drugName': 'Methotrexate', 'tradeNames_list': "['Amethopterin', 'Ebetrex', 'Emtexate high-pot', 'Emtexate pf', 'FolexMaxtrex', 'Methotrexate', 'Metoject', 'Mexate', 'Otrexup', 'Otrexup pfsRasuvo', 'Reditrex', 'Rheumatrex', 'Trexall', 'Zlatal']", 'syns_list': "['(r)... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1174 | Q6 | What genes does Selinexor target when it's used to treat cancer? | When used to treat cancer, the drug Selinexor targets the gene XPO1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%selinexor%" OR LOWER(tradeNames_list) LIKE "%seli... | [{'UUID': 'DrugTargetsIndication121923_text_1195439', 'drugName': 'Selinexor', 'tradeNames_list': "['Xpovio']", 'syns_list': "['KPT-330', 'Selinexor']", 'target': 'ENSG00000082898', 'approvedSymbol': 'XPO1', 'approvedName': 'exportin 1', 'mesh_heading': 'Neoplasms', 'efo_term': 'cancer', 'yearOfFirstApproval': 2019, 'm... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1487 | Q6 | What genes does Pralsetinib target when it's used to treat neoplasm? | When used to treat neoplasm, the drug Pralsetinib targets the genes RET, CCDC6, and KIF5B. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%pralsetinib%" OR LOWER(tradeNames_list) LIKE "%pr... | [{'UUID': 'DrugTargetsIndication121923_text_944300', 'drugName': 'Pralsetinib', 'tradeNames_list': "['Gavreto']", 'syns_list': "[':pralsetinib', 'BLU-123244', 'BLU-667', 'BLU123244', 'Blu-667', 'PralsetinibX-581238', 'X581238']", 'target': 'ENSG00000165731', 'approvedSymbol': 'RET', 'approvedName': 'ret proto-oncogene'... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1456 | Q6 | What genes does Gabapentin target when it's used to treat Intervertebral Disc Displacement? | Gabapentin has not been approved by the FDA as a treatment for Intervertebral Disc Displacement, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are CACNA1B, CACNA1C, CACNA1S, CACNA1D, CACNA1F, CACNA2D2, CACNA2D1, CACNA1H, CACNA1G, CACNA1I, CACNA1A, CACNA2D3, CAC... | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%gabapentin%" OR LOWER(tradeNames_list) LIKE "%gab... | [{'UUID': 'DrugTargetsIndication121923_text_895020', 'drugName': 'Gabapentin', 'tradeNames_list': "['Gabapentin', 'Gralise', 'Neurontin']", 'syns_list': "['CI-945', 'DM-1796', 'GOE 3450', 'GOE-3450', 'Gabapentin', 'NSC-742194NSC-759254']", 'target': 'ENSG00000148408', 'approvedSymbol': 'CACNA1B', 'approvedName': 'calci... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.253 | Q6 | What genes does Methotrexate target when it's used to treat fungal infectious disease? | When used to treat fungal infectious disease, the drug Methotrexate targets the gene DHFR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%methotrexate%" OR LOWER(tradeNames_list) LIKE "%m... | [{'UUID': 'DrugTargetsIndication121923_text_1057600', 'drugName': 'Methotrexate', 'tradeNames_list': "['Amethopterin', 'Ebetrex', 'Emtexate high-pot', 'Emtexate pf', 'FolexMaxtrex', 'Methotrexate', 'Metoject', 'Mexate', 'Otrexup', 'Otrexup pfsRasuvo', 'Reditrex', 'Rheumatrex', 'Trexall', 'Zlatal']", 'syns_list': "['(r)... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.419 | Q6 | What genes does Fluticasone Furoate target when it's used to treat chronic obstructive pulmonary disease? | When used to treat chronic obstructive pulmonary disease, the drug Fluticasone Furoate targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fluticasone furoate%" OR LOWER(tradeNames_list) L... | [{'UUID': 'DrugTargetsIndication121923_text_225659', 'drugName': 'Fluticasone Furoate', 'tradeNames_list': "['Arnuity ellipta', 'Avamys', 'Flonase sensimist allergy reliefRelvar ellipta', 'Trelegy ellipta', 'Veramyst']", 'syns_list': "['Allermist', 'Ennhale', 'Fluticasone furoate', 'Furamist', 'GSK 685 698GSK-685968', ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1590 | Q6 | What genes does Duvelisib target when it's used to treat cancer? | When used to treat cancer, the drug Duvelisib targets the genes PIK3CD and PIK3CG. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%duvelisib%" OR LOWER(tradeNames_list) LIKE "%duve... | [{'UUID': 'DrugTargetsIndication121923_text_858837', 'drugName': 'Duvelisib', 'tradeNames_list': "['Copiktra']", 'syns_list': "['Duvelisib', 'Duvelisib hydrate', 'Duvelisib monohydrate', 'INK-1147INK-1197', 'IPI-145']", 'target': 'ENSG00000171608', 'approvedSymbol': 'PIK3CD', 'approvedName': 'phosphatidylinositol-4,5-b... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1895 | Q6 | What genes does Cetirizine Hydrochloride target when it's used to treat allergic rhinitis? | When used to treat allergic rhinitis, the drug Cetirizine Hydrochloride targets the gene HRH1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%cetirizine hydrochloride%" OR LOWER(tradeNames_li... | [{'UUID': 'DrugTargetsIndication121923_text_455806', 'drugName': 'Cetirizine Hydrochloride', 'tradeNames_list': '[\'Allacan\', \'Allertek\', \'Becoallergy\', \'Cetec\', \'Cetirizine hydrochlorideCetirizine hydrochloride allergy\', \'Cetirizine hydrochloride hivesCetirizine hydrochloride hives relief\', "CetirocolChildr... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.582 | Q6 | What genes does Omeprazole target when it's used to treat idiopathic pulmonary fibrosis? | Omeprazole has not been approved by the FDA as a treatment for idiopathic pulmonary fibrosis, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are ATP4A and ATP4B. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%omeprazole%" OR LOWER(tradeNames_list) LIKE "%ome... | [{'UUID': 'DrugTargetsIndication121923_text_1098287', 'drugName': 'Omeprazole', 'tradeNames_list': "['Antra', 'Losec', 'Losec mups', 'Mezzopram', 'Mopral', 'Omeprazole', 'OmeranPrilosec', 'Zanprol']", 'syns_list': "['H 168/68', 'H-168/68', 'NSC-751450', 'NSC-759192', 'Omeprazole']", 'target': 'ENSG00000186009', 'approv... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.314 | Q6 | What genes does Glycopyrrolate target when it's used to treat gastrointestinal disease? | When used to treat gastrointestinal disease, the drug Glycopyrrolate targets the genes CHRM3 and CHRM1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%glycopyrrolate%" OR LOWER(tradeNames_list) LIKE "... | [{'UUID': 'DrugTargetsIndication121923_text_857535', 'drugName': 'Glycopyrrolate', 'tradeNames_list': "['Cuvposa', 'Dartisla odt', 'Glycopyrrolate', 'Glyrx-pfLonhala magnair kit', 'Robinul', 'Robinul forte', 'Robinul fte', 'SeebriSialanar']", 'syns_list': "['AD-237', 'AHR-504', 'CHF-5259', 'CHF5259', 'GlycopyrrolateGly... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1962 | Q6 | What genes does Cabozantinib target when it's used to treat papillary thyroid carcinoma? | Cabozantinib has not been approved by the FDA as a treatment for papillary thyroid carcinoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are KDR and MET. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%cabozantinib%" OR LOWER(tradeNames_list) LIKE "%c... | [{'UUID': 'DrugTargetsIndication121923_text_669673', 'drugName': 'Cabozantinib S-Malate', 'tradeNames_list': "['Cabometyx', 'Cometriq']", 'syns_list': "['BMS-907351', 'Cabozantinib malate', 'Cabozantinib s-malate', 'XL-184XL184']", 'target': 'ENSG00000128052', 'approvedSymbol': 'KDR', 'approvedName': 'kinase insert dom... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.387 | Q6 | What genes does Olodaterol Hydrochloride target when it's used to treat chronic obstructive pulmonary disease? | When used to treat chronic obstructive pulmonary disease, the drug Olodaterol Hydrochloride targets the gene ADRB2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%olodaterol hydrochloride%" OR LOWER(tradeNames_li... | [{'UUID': 'DrugTargetsIndication121923_text_937110', 'drugName': 'Olodaterol Hydrochloride', 'tradeNames_list': "['Striverdi respimat']", 'syns_list': "['BI 1744 CL', 'BI-1744 CL', 'BI-1744-CL', 'Olodaterol hydrochloride']", 'target': 'ENSG00000169252', 'approvedSymbol': 'ADRB2', 'approvedName': 'adrenoceptor beta 2', ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.541 | Q6 | What genes does Peginesatide Acetate target when it's used to treat anemia (phenotype)? | When used to treat anemia (phenotype), the drug Peginesatide Acetate targets the gene EPOR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%peginesatide acetate%" OR LOWER(tradeNames_list) ... | [{'UUID': 'DrugTargetsIndication121923_text_1103069', 'drugName': 'Peginesatide Acetate', 'tradeNames_list': "['Omontys', 'Omontys preservative free']", 'syns_list': "['AF37702', 'Hematide acetate', 'Peginesatide acetate']", 'target': 'ENSG00000187266', 'approvedSymbol': 'EPOR', 'approvedName': 'erythropoietin receptor... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.431 | Q6 | What genes does Selinexor target when it's used to treat multiple myeloma? | When used to treat multiple myeloma, the drug Selinexor targets the gene XPO1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%selinexor%" OR LOWER(tradeNames_list) LIKE "%seli... | [{'UUID': 'DrugTargetsIndication121923_text_1193930', 'drugName': 'Selinexor', 'tradeNames_list': "['Xpovio']", 'syns_list': "['KPT-330', 'Selinexor']", 'target': 'ENSG00000082898', 'approvedSymbol': 'XPO1', 'approvedName': 'exportin 1', 'mesh_heading': 'Multiple Myeloma', 'efo_term': 'multiple myeloma', 'yearOfFirstAp... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.657 | Q6 | What genes does Abaloparatide target when it's used to treat osteoporosis? | When used to treat osteoporosis, the drug Abaloparatide targets the gene PTH1R. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%abaloparatide%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_1025249', 'drugName': 'Abaloparatide', 'tradeNames_list': "['Tymlos']", 'syns_list': "['Abaloparatide', 'BA-058', 'BA058', 'BIM-44058']", 'target': 'ENSG00000160801', 'approvedSymbol': 'PTH1R', 'approvedName': 'parathyroid hormone 1 receptor', 'mesh_heading': 'Osteoporosis', ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1642 | Q6 | What genes does Phenylephrine Hydrochloride target when it's used to treat allergic disease? | When used to treat allergic disease, the drug Phenylephrine Hydrochloride targets the genes ADRA1A, ADRA1D, and ADRA1B. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%phenylephrine hydrochloride%" OR LOWER(tradeNames... | [{'UUID': 'DrugTargetsIndication121923_text_416705', 'drugName': 'Phenylephrine Hydrochloride', 'tradeNames_list': "['Afrin 4 hour nasal spray', 'Biomydrin', 'Biorphen', 'Fenilfar', 'FenoxMydfrin', 'Nazex', 'Neo-synephrine', 'Neosynephrine', 'NostrilNurofen sinus pain relief', 'Phenylephrine hydrochloride', 'PrefrinVaz... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1318 | Q6 | What genes does Naloxegol Oxalate target when it's used to treat constipation disorder? | When used to treat constipation disorder, the drug Naloxegol Oxalate targets the gene OPRM1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%naloxegol oxalate%" OR LOWER(tradeNames_list) LIK... | [{'UUID': 'DrugTargetsIndication121923_text_763361', 'drugName': 'Naloxegol Oxalate', 'tradeNames_list': "['Movantik']", 'syns_list': "['AZ13337019 oxalate', 'NKTR-118 oxalate', 'Naloxegol oxalate']", 'target': 'ENSG00000112038', 'approvedSymbol': 'OPRM1', 'approvedName': 'opioid receptor mu 1', 'mesh_heading': 'Consti... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1358 | Q6 | What genes does Daridorexant Hydrochloride target when it's used to treat insomnia? | When used to treat insomnia, the drug Daridorexant Hydrochloride targets the genes HCRTR2 and HCRTR1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%daridorexant hydrochloride%" OR LOWER(tradeNames_... | [{'UUID': 'DrugTargetsIndication121923_text_1076447', 'drugName': 'Daridorexant Hydrochloride', 'tradeNames_list': "['Quviviq']", 'syns_list': "['ACT-541468A', 'Daridorexant hydrochloride', 'Nemorexant hydrochlorideQuviviq']", 'target': 'ENSG00000137252', 'approvedSymbol': 'HCRTR2', 'approvedName': 'hypocretin receptor... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.414 | Q6 | What genes does Dexlansoprazole target when it's used to treat gastric ulcer? | When used to treat gastric ulcer, the drug Dexlansoprazole targets the genes ATP4A and ATP4B. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dexlansoprazole%" OR LOWER(tradeNames_list) LIKE ... | [{'UUID': 'DrugTargetsIndication121923_text_1098465', 'drugName': 'Dexlansoprazole', 'tradeNames_list': "['Dexilant', 'Dexilant solutab', 'Kapidex']", 'syns_list': "['(r)-lansoprazole', 'Dexlansoprazole', 'Kapidex', 'Lansoprazole r-formLansoprazole, (r)-', 'NSC-758710', 'T-168390', 'TAK-390']", 'target': 'ENSG000001056... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1615 | Q6 | What genes does Spironolactone target when it's used to treat cirrhosis of liver? | When used to treat cirrhosis of liver, the drug Spironolactone targets the gene NR3C2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%spironolactone%" OR LOWER(tradeNames_list) LIKE "... | [{'UUID': 'DrugTargetsIndication121923_text_1094543', 'drugName': 'Spironolactone', 'tradeNames_list': "['Abbolactone', 'Aldactone', 'Carospir', 'Diatensec', 'Gx spironolLaractone', 'Spiretic', 'Spiroctan 100', 'Spiroctan 25', 'Spiroctan 50Spironolactone', 'Spirospare 100', 'Spirospare 25']", 'syns_list': "['NSC-150399... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.687 | Q6 | What genes does Aspirin target when it's used to treat mucocutaneous lymph node syndrome? | Aspirin has not been approved by the FDA as a treatment for mucocutaneous lymph node syndrome, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%aspirin%" OR LOWER(tradeNames_list) LIKE "%aspiri... | [{'UUID': 'DrugTargetsIndication121923_text_834381', 'drugName': 'Aspirin', 'tradeNames_list': "['8-hour bayer', 'Acetosalic Acid', 'Acetylsalic acidAcetylsalicylic Acid', 'Alka rapid', 'Anadin all night', 'Angettes 75Aspirin', 'Aspro clr', 'Bayer extra strength aspirin for migraine painDanamep', 'Disprin cv', 'Disprin... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.621 | Q6 | What genes does Riluzole target when it's used to treat atrial fibrillation? | Riluzole has not been approved by the FDA as a treatment for atrial fibrillation, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%riluzole%" OR LOWER(tradeNames_list) LIKE "%riluz... | [{'UUID': 'DrugTargetsIndication121923_text_636319', 'drugName': 'Riluzole', 'tradeNames_list': "['Exservan', 'Rilutek', 'Riluzole', 'Teglutik', 'Tiglutik kit']", 'syns_list': "['BHV-0223', 'NSC-753433', 'NSC-759823', 'RP 54274', 'RP-54274', 'RiluzoleTiglutik']", 'target': 'ENSG00000183873', 'approvedSymbol': 'SCN5A', ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.923 | Q6 | What genes does Rufinamide target when it's used to treat Seizure? | When used to treat Seizure, the drug Rufinamide targets the genes SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%rufinamide%" OR LOWER(tradeNames_list) LIKE "%ruf... | [{'UUID': 'DrugTargetsIndication121923_text_652673', 'drugName': 'Rufinamide', 'tradeNames_list': "['Banzel', 'Inovelon', 'Rufinamide']", 'syns_list': "['60231/4', 'CGP 33101', 'CGP-33101', 'E-2080', 'E2080', 'RUF 331', 'RUF-331Rufinamide']", 'target': 'ENSG00000144285', 'approvedSymbol': 'SCN1A', 'approvedName': 'sodi... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1199 | Q6 | What genes does Dacomitinib target when it's used to treat non-small cell lung carcinoma? | When used to treat non-small cell lung carcinoma, the drug Dacomitinib targets the genes EGFR, ERBB2, and ERBB4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dacomitinib%" OR LOWER(tradeNames_list) LIKE "%da... | [{'UUID': 'DrugTargetsIndication121923_text_217107', 'drugName': 'Dacomitinib', 'tradeNames_list': "['Vizimpro']", 'syns_list': "['Dacomitinib', 'Dacomitinib hydrate', 'Dacomitinib monohydratePF-00299804-03', 'Pf-00299804']", 'target': 'ENSG00000146648', 'approvedSymbol': 'EGFR', 'approvedName': 'epidermal growth facto... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.839 | Q6 | What genes does Lenvatinib Mesylate target when it's used to treat thyroid carcinoma? | When used to treat thyroid carcinoma, the drug Lenvatinib Mesylate targets the genes KDR, FLT1, and FLT4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lenvatinib mesylate%" OR LOWER(tradeNames_list) L... | [{'UUID': 'DrugTargetsIndication121923_text_690183', 'drugName': 'Lenvatinib Mesylate', 'tradeNames_list': "['Lenvima']", 'syns_list': "['E-7080 MESYLATE', 'E7080', 'E7080 MESYLATE', 'Lenvatinib mesilateLenvatinib mesylate', 'Lenvatinib methanesulfonate']", 'target': 'ENSG00000128052', 'approvedSymbol': 'KDR', 'approve... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1771 | Q6 | What genes does Encorafenib target when it's used to treat melanoma? | When used to treat melanoma, the drug Encorafenib targets the gene BRAF. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%encorafenib%" OR LOWER(tradeNames_list) LIKE "%en... | [{'UUID': 'DrugTargetsIndication121923_text_752253', 'drugName': 'Encorafenib', 'tradeNames_list': "['Braftovi']", 'syns_list': "['Encorafenib', 'Lgx-818', 'Lgx818', 'NVP-LGX-818-NXA', 'NVP-LGX818NVP-LGX818-NXA']", 'target': 'ENSG00000157764', 'approvedSymbol': 'BRAF', 'approvedName': 'B-Raf proto-oncogene, serine/thre... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
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