uuid stringlengths 4 8 | template_uuid stringclasses 40
values | question stringlengths 13 193 | answer stringlengths 29 2.2k | benchmark_query stringlengths 133 622 | execution_results stringlengths 2 1.14M | query_type stringclasses 2
values | sql_category stringclasses 26
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Q6.953 | Q6 | What genes does Montelukast target when it's used to treat seasonal allergic rhinitis? | When used to treat seasonal allergic rhinitis, the drug Montelukast targets the gene CYSLTR1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%montelukast%" OR LOWER(tradeNames_list) LIKE "%mo... | [{'UUID': 'DrugTargetsIndication121923_text_1100392', 'drugName': 'Montelukast Sodium', 'tradeNames_list': "['Montelukast sodium', 'Singulair']", 'syns_list': "['MK-476', 'Montelukast (as sodium)', 'Montelukast monosodium saltMontelukast sodium', 'NSC-759107']", 'target': 'ENSG00000173198', 'approvedSymbol': 'CYSLTR1',... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.185 | Q6 | What genes does Dexamethasone target when it's used to treat lateral epicondylitis? | When used to treat lateral epicondylitis, the drug Dexamethasone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dexamethasone%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_227799', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1072 | Q6 | What genes does Clevidipine target when it's used to treat cardiovascular disease? | When used to treat cardiovascular disease, the drug Clevidipine targets the genes CACNA1C, CACNA1S, CACNA1D, and CACNA1F. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%clevidipine%" OR LOWER(tradeNames_list) LIKE "%cl... | [{'UUID': 'DrugTargetsIndication121923_text_1044221', 'drugName': 'Clevidipine', 'tradeNames_list': "['Cleviprex']", 'syns_list': "['Clevidepine', 'Clevidepine butyrate', 'Clevidipine', 'Clevidipine butyrate']", 'target': 'ENSG00000151067', 'approvedSymbol': 'CACNA1C', 'approvedName': 'calcium voltage-gated channel sub... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.711 | Q6 | What genes does Tofacitinib Citrate target when it's used to treat rheumatoid arthritis? | When used to treat rheumatoid arthritis, the drug Tofacitinib Citrate targets the genes JAK1, JAK3, TYK2, and JAK2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%tofacitinib citrate%" OR LOWER(tradeNames_list) L... | [{'UUID': 'DrugTargetsIndication121923_text_848324', 'drugName': 'Tofacitinib Citrate', 'tradeNames_list': "['Xeljanz', 'Xeljanz xr']", 'syns_list': "['CP-690,550-10', 'CP-690550-10', 'Cp-690550 citrate', 'Tasocitinib citrateTasocitinib monocitrate', 'Tofacitinib citrate', 'Tofacitinib monocitrate']", 'target': 'ENSG00... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.173 | Q6 | What genes does Mirabegron target when it's used to treat nephrolithiasis? | Mirabegron has not been approved by the FDA as a treatment for nephrolithiasis, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is ADRB3. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%mirabegron%" OR LOWER(tradeNames_list) LIKE "%mir... | [{'UUID': 'DrugTargetsIndication121923_text_937770', 'drugName': 'Mirabegron', 'tradeNames_list': "['Betmiga', 'Myrbetriq', 'Myrbetriq granules']", 'syns_list': "['Betanis', 'Mirabegron', 'YM-178', 'YM178']", 'target': 'ENSG00000188778', 'approvedSymbol': 'ADRB3', 'approvedName': 'adrenoceptor beta 3', 'mesh_heading': ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.296 | Q6 | What genes does Indomethacin target when it's used to treat ankylosing spondylitis? | When used to treat ankylosing spondylitis, the drug Indomethacin targets the genes PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%indomethacin%" OR LOWER(tradeNames_list) LIKE "%i... | [{'UUID': 'DrugTargetsIndication121923_text_828373', 'drugName': 'Indomethacin', 'tradeNames_list': "['Artracin', 'Artracin sr', 'Berlind 75 ret', 'Flexin-25 continusFlexin-50 continus', 'Flexin-75 continus', 'Imbrilon', 'Indo-lemmonIndo-paed', 'Indocid ret', 'Indocid-r', 'Indocin', 'Indocin sr', 'IndodermIndoflex', 'I... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.554 | Q6 | What genes does Palbociclib target when it's used to treat breast carcinoma? | When used to treat breast carcinoma, the drug Palbociclib targets the genes CDK4, CDK6, and CCND1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%palbociclib%" OR LOWER(tradeNames_list) LIKE "%pa... | [{'UUID': 'DrugTargetsIndication121923_text_851575', 'drugName': 'Palbociclib', 'tradeNames_list': "['Ibrance']", 'syns_list': "['PD-0332991', 'Palbociclib']", 'target': 'ENSG00000135446', 'approvedSymbol': 'CDK4', 'approvedName': 'cyclin dependent kinase 4', 'mesh_heading': 'Breast Neoplasms', 'efo_term': 'breast carc... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.763 | Q6 | What genes does Odevixibat target when it's used to treat Pruritus? | When used to treat Pruritus, the drug Odevixibat targets the gene SLC10A2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%odevixibat%" OR LOWER(tradeNames_list) LIKE "%ode... | [{'UUID': 'DrugTargetsIndication121923_text_992746', 'drugName': 'Odevixibat', 'tradeNames_list': "['Bylvay']", 'syns_list': "['A-4250', 'A4250', 'AR-H064974', 'AZD-8294', 'AZD8294', 'OdevixibatOdevixibat sesquihydrate']", 'target': 'ENSG00000125255', 'approvedSymbol': 'SLC10A2', 'approvedName': 'solute carrier family ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.304 | Q6 | What genes does Apalutamide target when it's used to treat neoplasm? | When used to treat neoplasm, the drug Apalutamide targets the gene AR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%apalutamide%" OR LOWER(tradeNames_list) LIKE "%ap... | [{'UUID': 'DrugTargetsIndication121923_text_921897', 'drugName': 'Apalutamide', 'tradeNames_list': "['Erleada']", 'syns_list': "['ARN-509', 'Apalutamide', 'Arn-509', 'JNJ-56021927']", 'target': 'ENSG00000169083', 'approvedSymbol': 'AR', 'approvedName': 'androgen receptor', 'mesh_heading': 'Neoplasms', 'efo_term': 'canc... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1878 | Q6 | What genes does Dabigatran Etexilate target when it's used to treat thrombotic disease? | When used to treat thrombotic disease, the drug Dabigatran Etexilate targets the gene F2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dabigatran etexilate%" OR LOWER(tradeNames_list) ... | [{'UUID': 'DrugTargetsIndication121923_text_1092728', 'drugName': 'Dabigatran Etexilate', 'tradeNames_list': "['Pradaxa']", 'syns_list': "['BIBR 1048', 'BIBR 1048 BS RS1', 'BIBR-1048', 'BIBR-1048-BS-RS1Dabigatran etexilate', 'Dabigatran etexilate methanesulfonate']", 'target': 'ENSG00000180210', 'approvedSymbol': 'F2',... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1093 | Q6 | What genes does Clozapine target when it's used to treat psychosis? | When used to treat psychosis, the drug Clozapine targets the genes DRD2 and HTR2A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%clozapine%" OR LOWER(tradeNames_list) LIKE "%cloz... | [{'UUID': 'DrugTargetsIndication121923_text_157984', 'drugName': 'Clozapine', 'tradeNames_list': "['Clozapine', 'Clozaril', 'Fazaclo', 'Fazaclo odt', 'Versacloz', 'Zaponex']", 'syns_list': "['Clozapine', 'Clozapine (caraco)', 'Clozapine (clozaril)Clozapine (fazaclo)', 'Clozapine (ivax)', 'Clozapine (mylan)Clozapine (te... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1747 | Q6 | What genes does Palonosetron Hydrochloride target when it's used to treat Nausea and vomiting? | When used to treat Nausea and vomiting, the drug Palonosetron Hydrochloride targets the gene HTR3A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%palonosetron hydrochloride%" OR LOWER(tradeNames_... | [{'UUID': 'DrugTargetsIndication121923_text_205500', 'drugName': 'Palonosetron Hydrochloride', 'tradeNames_list': "['Aloxi', 'Palonosetron hydrochloride']", 'syns_list': "['Palonocetron hydrochloride', 'Palonosetron (as hydrochloride)Palonosetron hcl', 'Palonosetron hydrochloride', 'RS-25259-197']", 'target': 'ENSG0000... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1652 | Q6 | What genes does Pazopanib Hydrochloride target when it's used to treat clear cell renal carcinoma? | When used to treat clear cell renal carcinoma, the drug Pazopanib Hydrochloride targets the genes KDR, FGFR1, FGFR3, FLT1, KIT, FLT4, PDGFRB, PDGFRA, LCK, CSF1R, and ITK. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%pazopanib hydrochloride%" OR LOWER(tradeNames_lis... | [{'UUID': 'DrugTargetsIndication121923_text_667963', 'drugName': 'Pazopanib Hydrochloride', 'tradeNames_list': "['Votrient']", 'syns_list': "['GW-786034B', 'GW786034B', 'Pazopanib (as hydrochloride)', 'Pazopanib hclPazopanib hydrochloride', 'Pazopanib monohydrochloride']", 'target': 'ENSG00000068078', 'approvedSymbol':... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.914 | Q6 | What genes does Doxycycline target when it's used to treat malaria? | When used to treat malaria, the drug Doxycycline targets the genes MMP7, MMP1, MMP13, and MMP8. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%doxycycline%" OR LOWER(tradeNames_list) LIKE "%do... | [{'UUID': 'DrugTargetsIndication121923_text_1038220', 'drugName': 'Doxycycline', 'tradeNames_list': "['Doxychel', 'Doxycycline', 'Monodox', 'Oracea', 'Vibramycin']", 'syns_list': "['Doxirobe', 'Doxycycline', 'Doxycycline monohydrate', 'Doxylin', 'GS-3065Supracyclin', 'Xyrosa']", 'target': 'ENSG00000137673', 'approvedSy... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1932 | Q6 | What genes does Ipratropium Bromide target when it's used to treat Airway obstruction? | When used to treat Airway obstruction, the drug Ipratropium Bromide targets the gene CHRM3. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ipratropium bromide%" OR LOWER(tradeNames_list) L... | [{'UUID': 'DrugTargetsIndication121923_text_857473', 'drugName': 'Ipratropium Bromide', 'tradeNames_list': "['Atrovent', 'Atrovent aerocaps', 'Atrovent fte', 'Atrovent hfaAtrovent udvs', 'Ipratrop', 'Ipratrop steripoule', 'Ipratropium bromideRespontin', 'Rinatec', 'Tropiovent']", 'syns_list': "['Ipratropium bromide', '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.275 | Q6 | What genes does Capsaicin target when it's used to treat head and neck malignant neoplasia? | Capsaicin has not been approved by the FDA as a treatment for head and neck malignant neoplasia, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is TRPV1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%capsaicin%" OR LOWER(tradeNames_list) LIKE "%caps... | [{'UUID': 'DrugTargetsIndication121923_text_993214', 'drugName': 'Capsaicin', 'tradeNames_list': "['Qutenza', 'Zacin', 'Zostrix', 'Zostrix hp']", 'syns_list': "['ALGRX 4975', 'ALGRX-4975', 'Ausanil', 'Axsain', 'Capsaicin', 'Capzasin-hpCntx-4975', 'Dolenon', 'FEMA NO. 3404', 'Mioton', 'NGX-1998', 'NGX-4010NSC-56353', 'N... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1147 | Q6 | What genes does Naproxen target when it's used to treat Headache? | When used to treat Headache, the drug Naproxen targets the genes PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%naproxen%" OR LOWER(tradeNames_list) LIKE "%napro... | [{'UUID': 'DrugTargetsIndication121923_text_838531', 'drugName': 'Naproxen', 'tradeNames_list': "['Aleve', 'Anaprox', 'Arthrosin 250', 'Arthrosin 250 ec', 'Arthrosin 500Arthrosin 500 ec', 'Condrotec', 'Ec-naprosyn', 'Equiproxen', 'Feminax ultraGrenoxal', 'Kenosyn', 'Laraflex', 'Napratec op', 'Naprosyn', 'Naprosyn 375Na... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1589 | Q6 | What genes does Lenalidomide target when it's used to treat pancreatic carcinoma? | Lenalidomide has not been approved by the FDA as a treatment for pancreatic carcinoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are CRBN, DDB1, CUL4A, and RBX1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lenalidomide%" OR LOWER(tradeNames_list) LIKE "%l... | [{'UUID': 'DrugTargetsIndication121923_text_1106125', 'drugName': 'Lenalidomide', 'tradeNames_list': "['Revlimid']", 'syns_list': "['CC-5013', 'CDC-501', 'Lenalidomide', 'NSC-747972', 'SYP-1512']", 'target': 'ENSG00000113851', 'approvedSymbol': 'CRBN', 'approvedName': 'cereblon', 'mesh_heading': 'Pancreatic Neoplasms',... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.700 | Q6 | What genes does Monomethyl Fumarate target when it's used to treat multiple sclerosis? | When used to treat multiple sclerosis, the drug Monomethyl Fumarate targets the gene KEAP1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%monomethyl fumarate%" OR LOWER(tradeNames_list) L... | [{'UUID': 'DrugTargetsIndication121923_text_1055635', 'drugName': 'Monomethyl Fumarate', 'tradeNames_list': "['Bafiertam']", 'syns_list': "['Fumaric acid monomethyl ester', 'Methyl Fumarate', 'Monomethyl fumarateNSC-523835']", 'target': 'ENSG00000079999', 'approvedSymbol': 'KEAP1', 'approvedName': 'kelch like ECH assoc... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1765 | Q6 | What genes does Netarsudil Dimesylate target when it's used to treat open-angle glaucoma? | When used to treat open-angle glaucoma, the drug Netarsudil Dimesylate targets the genes ROCK2 and ROCK1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%netarsudil dimesylate%" OR LOWER(tradeNames_list)... | [{'UUID': 'DrugTargetsIndication121923_text_1076334', 'drugName': 'Netarsudil Dimesylate', 'tradeNames_list': "['Rhopressa']", 'syns_list': "['AR-13324', 'Netarsudil dimesylate', 'Netarsudil mesilateNetarsudil mesylate']", 'target': 'ENSG00000134318', 'approvedSymbol': 'ROCK2', 'approvedName': 'Rho associated coiled-co... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.488 | Q6 | What genes does Lenalidomide target when it's used to treat Mantle cell lymphoma? | When used to treat Mantle cell lymphoma, the drug Lenalidomide targets the genes CRBN, DDB1, CUL4A, and RBX1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lenalidomide%" OR LOWER(tradeNames_list) LIKE "%l... | [{'UUID': 'DrugTargetsIndication121923_text_1106173', 'drugName': 'Lenalidomide', 'tradeNames_list': "['Revlimid']", 'syns_list': "['CC-5013', 'CDC-501', 'Lenalidomide', 'NSC-747972', 'SYP-1512']", 'target': 'ENSG00000113851', 'approvedSymbol': 'CRBN', 'approvedName': 'cereblon', 'mesh_heading': 'Lymphoma, Mantle-Cell'... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.428 | Q6 | What genes does Lidocaine Hydrochloride target when it's used to treat prostate carcinoma? | When used to treat prostate carcinoma, the drug Lidocaine Hydrochloride targets the genes SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lidocaine hydrochloride%" OR LOWER(tradeNames_lis... | [{'UUID': 'DrugTargetsIndication121923_text_637008', 'drugName': 'Lidocaine Hydrochloride', 'tradeNames_list': "['Akten', 'Alphacaine hydrochloride', 'Anestacon', 'Anodesyn', 'BismodyneBradosol plus', 'Calgel', 'Co-phenylcaine fte', 'Denela', 'DequasprayEmla', 'Germoloids', 'Germoloids complete', 'Glydo', 'Hemocane', '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.377 | Q6 | What genes does Lisdexamfetamine Dimesylate target when it's used to treat glaucoma? | When used to treat glaucoma, the drug Lisdexamfetamine Dimesylate targets the genes SLC6A2, SLC18A2, and SLC6A3. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lisdexamfetamine dimesylate%" OR LOWER(tradeNames... | [{'UUID': 'DrugTargetsIndication121923_text_419191', 'drugName': 'Lisdexamfetamine Dimesylate', 'tradeNames_list': "['Elvanse', 'Elvanse adult', 'Vyvanse']", 'syns_list': "['Lisdexamfetamine dimesilate', 'Lisdexamfetamine dimesylateLisdexamfetamine dimethanesulfonate', 'Lisdexamfetamine mesilateLisdexamphetamine dimesi... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1008 | Q6 | What genes does Lamotrigine target when it's used to treat epilepsy? | When used to treat epilepsy, the drug Lamotrigine targets the genes SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lamotrigine%" OR LOWER(tradeNames_list) LIKE "%la... | [{'UUID': 'DrugTargetsIndication121923_text_653275', 'drugName': 'Lamotrigine', 'tradeNames_list': "['Lamictal', 'Lamictal cd', 'Lamictal odt', 'Lamictal xr', 'Lamotrigine']", 'syns_list': "['BW 430C', 'BW-430C', 'Lamotrigine', 'NSC-759171']", 'target': 'ENSG00000144285', 'approvedSymbol': 'SCN1A', 'approvedName': 'sod... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1003 | Q6 | What genes does Famotidine target when it's used to treat gastroesophageal reflux disease? | When used to treat gastroesophageal reflux disease, the drug Famotidine targets the gene HRH2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%famotidine%" OR LOWER(tradeNames_list) LIKE "%fam... | [{'UUID': 'DrugTargetsIndication121923_text_1100336', 'drugName': 'Famotidine', 'tradeNames_list': "['Famotidine', 'Famotidine preservative freeFamotidine preservative free (pharmacy bulk)', 'Fluxid', 'PepcidPepcid ac', 'Pepcid preservative free', 'Pepcid rpd']", 'syns_list': "['Amfamox', 'Fadul', 'Famodil', 'Famosan',... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1940 | Q6 | What genes does Gabapentin target when it's used to treat epilepsy? | When used to treat epilepsy, the drug Gabapentin targets the genes CACNA1B, CACNA1C, CACNA1S, CACNA1D, CACNA1F, CACNA2D2, CACNA2D1, CACNA1H, CACNA1G, CACNA1I, CACNA1A, CACNA2D3, CACNA2D4, CACNA1E, CACNB4, CACNB2, CACNB1, CACNB3, CACNG7, CACNG5, CACNG2, CACNG4, CACNG8, CACNG3, CACNG6, and CACNG1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%gabapentin%" OR LOWER(tradeNames_list) LIKE "%gab... | [{'UUID': 'DrugTargetsIndication121923_text_891809', 'drugName': 'Gabapentin Enacarbil', 'tradeNames_list': "['Horizant']", 'syns_list': "['ASP-8825', 'ASP8825', 'GSK1838262', 'Gabapentin enacarbilGabapentin encarbil', 'Gsk-1838262', 'XP 13512', 'XP-13512', 'XP13512']", 'target': 'ENSG00000148408', 'approvedSymbol': 'C... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.714 | Q6 | What genes does Pazopanib Hydrochloride target when it's used to treat papillary renal cell carcinoma? | When used to treat papillary renal cell carcinoma, the drug Pazopanib Hydrochloride targets the genes KDR, FGFR1, FGFR3, FLT1, KIT, FLT4, PDGFRB, PDGFRA, LCK, CSF1R, and ITK. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%pazopanib hydrochloride%" OR LOWER(tradeNames_lis... | [{'UUID': 'DrugTargetsIndication121923_text_667964', 'drugName': 'Pazopanib Hydrochloride', 'tradeNames_list': "['Votrient']", 'syns_list': "['GW-786034B', 'GW786034B', 'Pazopanib (as hydrochloride)', 'Pazopanib hclPazopanib hydrochloride', 'Pazopanib monohydrochloride']", 'target': 'ENSG00000068078', 'approvedSymbol':... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1335 | Q6 | What genes does Selumetinib Sulfate target when it's used to treat neurofibromatosis? | When used to treat neurofibromatosis, the drug Selumetinib Sulfate targets the genes MAP2K2 and MAP2K1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%selumetinib sulfate%" OR LOWER(tradeNames_list) L... | [{'UUID': 'DrugTargetsIndication121923_text_932819', 'drugName': 'Selumetinib Sulfate', 'tradeNames_list': "['Koselugo']", 'syns_list': "['AZD-6244 HYD-SULFATE', 'AZD-6244 HYDROGEN SULFATE', 'AZD6244 HYD-SULFATEAZD6244 HYDROGEN SULFATE', 'Azd-6244 hydrogen sulphateAzd6244 hydrogen sulphate', 'Selumetinib sulfate', 'Sel... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1156 | Q6 | What genes does Oxcarbazepine target when it's used to treat neuropathic pain? | Oxcarbazepine has not been approved by the FDA as a treatment for neuropathic pain, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%oxcarbazepine%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_632189', 'drugName': 'Oxcarbazepine', 'tradeNames_list': "['Oxcarbazepine', 'Oxtellar xr', 'Trileptal']", 'syns_list': "['GP-47680', 'KIN-493', 'NSC-758693', 'Oxcarbamazepine', 'OxcarbazepineSPN-804']", 'target': 'ENSG00000144285', 'approvedSymbol': 'SCN1A', 'approvedName': '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.338 | Q6 | What genes does Abrocitinib target when it's used to treat atopic eczema? | When used to treat atopic eczema, the drug Abrocitinib targets the gene JAK1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%abrocitinib%" OR LOWER(tradeNames_list) LIKE "%ab... | [{'UUID': 'DrugTargetsIndication121923_text_848713', 'drugName': 'Abrocitinib', 'tradeNames_list': "['Cibinqo']", 'syns_list': "['Abrocitinib', 'Cibinqo', 'PF-04965842', 'Pf-04965842']", 'target': 'ENSG00000162434', 'approvedSymbol': 'JAK1', 'approvedName': 'Janus kinase 1', 'mesh_heading': 'Dermatitis, Atopic', 'efo_t... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1343 | Q6 | What genes does Avacopan target when it's used to treat Anti-neutrophil cytoplasmic antibody-associated vasculitis? | When used to treat Anti-neutrophil cytoplasmic antibody-associated vasculitis, the drug Avacopan targets the gene C5AR1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%avacopan%" OR LOWER(tradeNames_list) LIKE "%avaco... | [{'UUID': 'DrugTargetsIndication121923_text_1191851', 'drugName': 'Avacopan', 'tradeNames_list': "['Tavneos']", 'syns_list': "['Avacopan', 'CCX-168', 'CCX168', 'Ccx168']", 'target': 'ENSG00000197405', 'approvedSymbol': 'C5AR1', 'approvedName': 'complement C5a receptor 1', 'mesh_heading': 'Anti-Neutrophil Cytoplasmic An... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1593 | Q6 | What genes does Testosterone target when it's used to treat Spinal cord injury? | Testosterone has not been approved by the FDA as a treatment for Spinal cord injury, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is AR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%testosterone%" OR LOWER(tradeNames_list) LIKE "%t... | [{'UUID': 'DrugTargetsIndication121923_text_922032', 'drugName': 'Testosterone Undecanoate', 'tradeNames_list': "['Andriol', 'Aveed', 'Jatenzo', 'Kyzatrex', 'Nebido', 'RestandolRestandol testocap', 'Tlando', 'Undestor']", 'syns_list': "['Kyzatrex', 'MK-3033', 'ORG 538', 'ORG-538', 'TSX-011Testosterone 17.beta.-undecyla... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1993 | Q6 | What genes does Erdafitinib target when it's used to treat cancer? | When used to treat cancer, the drug Erdafitinib targets the genes FGFR1, FGFR3, FGFR2, and FGFR4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%erdafitinib%" OR LOWER(tradeNames_list) LIKE "%er... | [{'UUID': 'DrugTargetsIndication121923_text_707573', 'drugName': 'Erdafitinib', 'tradeNames_list': "['Balversa']", 'syns_list': "['Erdafitinib', 'JNJ-42756493', 'Jnj-42756493']", 'target': 'ENSG00000068078', 'approvedSymbol': 'FGFR3', 'approvedName': 'fibroblast growth factor receptor 3', 'mesh_heading': 'Neoplasms', '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.598 | Q6 | What genes does Fingolimod Hydrochloride target when it's used to treat breast carcinoma? | Fingolimod Hydrochloride has not been approved by the FDA as a treatment for breast carcinoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are S1PR5, S1PR2, S1PR4, S1PR3, and S1PR1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fingolimod hydrochloride%" OR LOWER(tradeNames_li... | [{'UUID': 'DrugTargetsIndication121923_text_1036514', 'drugName': 'Fingolimod Hydrochloride', 'tradeNames_list': "['Gilenya']", 'syns_list': "['FTY-720 HYDROCHLORIDE', 'FTY720', 'FTY720 HYDROCHLORIDE', 'FingolimodFingolimod (as hydrochloride)', 'Fingolimod hclFingolimod hydrochlorid', 'Fingolimod hydrochloride', 'Gilen... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.16 | Q6 | What genes does Risedronate Sodium target when it's used to treat Paget disease? | When used to treat Paget disease, the drug Risedronate Sodium targets the gene FDPS. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%risedronate sodium%" OR LOWER(tradeNames_list) LI... | [{'UUID': 'DrugTargetsIndication121923_text_1099463', 'drugName': 'Risedronate Sodium', 'tradeNames_list': "['Actonel', 'Atelvia', 'Risedronate sodium']", 'syns_list': "['NE-58095', 'NE-58095 ANHYDROUS', 'NSC-722598', 'NSC-759280Risedronate monosodium', 'Risedronate sodiumRisedronate sodium anhydrous', 'Risedronic acid... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1855 | Q6 | What genes does Fluocinolone Acetonide target when it's used to treat macular retinal edema? | When used to treat macular retinal edema, the drug Fluocinolone Acetonide targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fluocinolone acetonide%" OR LOWER(tradeNames_list... | [{'UUID': 'DrugTargetsIndication121923_text_242242', 'drugName': 'Fluocinolone Acetonide', 'tradeNames_list': "['Capex', 'Derma-smoothe/fs', 'Dermotic', 'Fluocet', 'Fluocinolone acetonideFluonid', 'Fluotrex', 'Fs shampoo', 'Iluvien', 'Retisert', 'SynalarSynalar fte', 'Synalar-c', 'Synalar-hp', 'Synalar-n', 'Synandone',... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1634 | Q6 | What genes does Edoxaban Tosylate target when it's used to treat pulmonary embolism? | When used to treat pulmonary embolism, the drug Edoxaban Tosylate targets the gene F10. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%edoxaban tosylate%" OR LOWER(tradeNames_list) LIK... | [{'UUID': 'DrugTargetsIndication121923_text_710335', 'drugName': 'Edoxaban Tosylate', 'tradeNames_list': "['Savaysa']", 'syns_list': "['DU-176B', 'Edoxaban tosilate', 'Edoxaban tosylate']", 'target': 'ENSG00000126218', 'approvedSymbol': 'F10', 'approvedName': 'coagulation factor X', 'mesh_heading': 'Pulmonary Embolism'... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1686 | Q6 | What genes does Topiramate target when it's used to treat Seizure? | When used to treat Seizure, the drug Topiramate targets the genes SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, SCN10A, CA2, CA4, GABRA1, GABRB2, GABRG2, GABRB3, GABRA4, GABRG3, GABRQ, GABRA3, GABRP, GABRD, GABRG1, GABRB1, GABRE, GABRA2, GABRA5, GABRA6, GRIK1, GRIK5, GRIK4, GRIK2, GRIK3, GRIA4, GRIA3,... | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%topiramate%" OR LOWER(tradeNames_list) LIKE "%top... | [{'UUID': 'DrugTargetsIndication121923_text_460837', 'drugName': 'Topiramate', 'tradeNames_list': "['Epitomax', 'Eprontia', 'Qudexy xr', 'Topamax', 'Topamax sprinkleTopiramate', 'Trokendi xr']", 'syns_list': "['(-)-topiramate', 'Epitoma', 'Eprontia', 'MCN-4853', 'Qudexy', 'RWJ-17021RWJ-17021-000', 'Sincronil', 'Topamac... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.600 | Q6 | What genes does Nilotinib target when it's used to treat neoplasm? | When used to treat neoplasm, the drug Nilotinib targets the genes ABL1 and BCR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%nilotinib%" OR LOWER(tradeNames_list) LIKE "%nilo... | [{'UUID': 'DrugTargetsIndication121923_text_746682', 'drugName': 'Nilotinib', 'tradeNames_list': "['Tasigna']", 'syns_list': "['AMN 107', 'AMN-107', 'AMN107', 'NSC-747599', 'Nilotinib']", 'target': 'ENSG00000097007', 'approvedSymbol': 'ABL1', 'approvedName': 'ABL proto-oncogene 1, non-receptor tyrosine kinase', 'mesh_h... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.924 | Q6 | What genes does Albuterol Sulfate target when it's used to treat chronic obstructive pulmonary disease? | When used to treat chronic obstructive pulmonary disease, the drug Albuterol Sulfate targets the gene ADRB2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%albuterol sulfate%" OR LOWER(tradeNames_list) LIK... | [{'UUID': 'DrugTargetsIndication121923_text_936247', 'drugName': 'Albuterol Sulfate', 'tradeNames_list': "['Accuneb', 'Albuterol sulfate', 'Proair', 'Proair digihaler', 'Proair hfaProair respiclick', 'Proventil', 'Proventil-hfa', 'Ventolin', 'Ventolin hfaVentolin rotacaps', 'Volmax', 'Vospire er']", 'syns_list': "['Alb... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.471 | Q6 | What genes does Budesonide target when it's used to treat Rhinitis, Allergic, Perennial? | When used to treat Rhinitis, Allergic, Perennial, the drug Budesonide targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%budesonide%" OR LOWER(tradeNames_list) LIKE "%bud... | [{'UUID': 'DrugTargetsIndication121923_text_222618', 'drugName': 'Budesonide', 'tradeNames_list': "['Aircort', 'Budeflam aquanase', 'Budelin novolizer', 'BudenofalkBudesonide', 'Cortiment', 'Duoresp spiromax', 'Entocort', 'Entocort crEntocort ec', 'Ortikos', 'Preferid', 'Pulmaxan', 'PulmicortPulmicort flexhaler', 'Pulm... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.202 | Q6 | What genes does Budesonide target when it's used to treat chronic bronchitis? | When used to treat chronic bronchitis, the drug Budesonide targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%budesonide%" OR LOWER(tradeNames_list) LIKE "%bud... | [{'UUID': 'DrugTargetsIndication121923_text_222617', 'drugName': 'Budesonide', 'tradeNames_list': "['Aircort', 'Budeflam aquanase', 'Budelin novolizer', 'BudenofalkBudesonide', 'Cortiment', 'Duoresp spiromax', 'Entocort', 'Entocort crEntocort ec', 'Ortikos', 'Preferid', 'Pulmaxan', 'PulmicortPulmicort flexhaler', 'Pulm... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1206 | Q6 | What genes does Ipratropium Bromide target when it's used to treat seasonal allergic rhinitis? | When used to treat seasonal allergic rhinitis, the drug Ipratropium Bromide targets the gene CHRM3. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ipratropium bromide%" OR LOWER(tradeNames_list) L... | [{'UUID': 'DrugTargetsIndication121923_text_857478', 'drugName': 'Ipratropium Bromide', 'tradeNames_list': "['Atrovent', 'Atrovent aerocaps', 'Atrovent fte', 'Atrovent hfaAtrovent udvs', 'Ipratrop', 'Ipratrop steripoule', 'Ipratropium bromideRespontin', 'Rinatec', 'Tropiovent']", 'syns_list': "['Ipratropium bromide', '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1056 | Q6 | What genes does Dexamethasone target when it's used to treat age-related macular degeneration? | Dexamethasone has not been approved by the FDA as a treatment for age-related macular degeneration, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dexamethasone%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_227565', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1195 | Q6 | What genes does Sorafenib Tosylate target when it's used to treat clear cell renal carcinoma? | When used to treat clear cell renal carcinoma, the drug Sorafenib Tosylate targets the genes KDR, BRAF, FLT1, FLT3, KIT, FLT4, PDGFRB, RAF1, and RET. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%sorafenib tosylate%" OR LOWER(tradeNames_list) LI... | [{'UUID': 'DrugTargetsIndication121923_text_683537', 'drugName': 'Sorafenib Tosylate', 'tradeNames_list': "['Nexavar']", 'syns_list': "['BAY 54-9085', 'BAY-54-9085', 'Sorafenib tosilate', 'Sorafenib tosylate']", 'target': 'ENSG00000157764', 'approvedSymbol': 'BRAF', 'approvedName': 'B-Raf proto-oncogene, serine/threoni... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1300 | Q6 | What genes does Trametinib target when it's used to treat neoplasm? | When used to treat neoplasm, the drug Trametinib targets the genes MAP2K2 and MAP2K1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%trametinib%" OR LOWER(tradeNames_list) LIKE "%tra... | [{'UUID': 'DrugTargetsIndication121923_text_928032', 'drugName': 'Trametinib Dimethyl Sulfoxide', 'tradeNames_list': "['Mekinist']", 'syns_list': "['GSK-1120212B', 'GSK1120212B', 'Trametinib dimethyl sulfoxide']", 'target': 'ENSG00000126934', 'approvedSymbol': 'MAP2K2', 'approvedName': 'mitogen-activated protein kinase... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1276 | Q6 | What genes does Dexamethasone target when it's used to treat synovitis? | When used to treat synovitis, the drug Dexamethasone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dexamethasone%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_226942', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1814 | Q6 | What genes does Liraglutide target when it's used to treat Weight loss? | Liraglutide has not been approved by the FDA as a treatment for Weight loss, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is GLP1R. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%liraglutide%" OR LOWER(tradeNames_list) LIKE "%li... | [{'UUID': 'DrugTargetsIndication121923_text_1044527', 'drugName': 'Liraglutide', 'tradeNames_list': "['Saxenda', 'Victoza']", 'syns_list': "['Liraglutide', 'Liraglutide (rdna origin)', 'Liraglutide recombinantNN-2211', 'NN-9924', 'NN2211', 'NN9924', 'NNC 90-1170', 'NNC-90-1170']", 'target': 'ENSG00000112164', 'approved... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1402 | Q6 | What genes does Cariprazine Hydrochloride target when it's used to treat bipolar I disorder? | When used to treat bipolar I disorder, the drug Cariprazine Hydrochloride targets the genes DRD2 and DRD3. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%cariprazine hydrochloride%" OR LOWER(tradeNames_l... | [{'UUID': 'DrugTargetsIndication121923_text_199890', 'drugName': 'Cariprazine Hydrochloride', 'tradeNames_list': "['Vraylar']", 'syns_list': "['Cariprazine hcl', 'Cariprazine hydrochloride', 'RGH-188 HCL']", 'target': 'ENSG00000149295', 'approvedSymbol': 'DRD2', 'approvedName': 'dopamine receptor D2', 'mesh_heading': '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1807 | Q6 | What genes does Ropivacaine Hydrochloride target when it's used to treat pain? | When used to treat pain, the drug Ropivacaine Hydrochloride targets the genes SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ropivacaine hydrochloride%" OR LOWER(tradeNames_l... | [{'UUID': 'DrugTargetsIndication121923_text_635739', 'drugName': 'Ropivacaine Hydrochloride', 'tradeNames_list': "['Narapin', 'Naropin', 'Ropivacaine hydrochloride']", 'syns_list': "['Ropivacaine hcl', 'Ropivacaine hydrochlorideRopivacaine hydrochloride hydrateRopivacaine hydrochloride monohydrate']", 'target': 'ENSG00... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.661 | Q6 | What genes does Betamethasone Dipropionate target when it's used to treat psoriasis vulgaris? | When used to treat psoriasis vulgaris, the drug Betamethasone Dipropionate targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%betamethasone dipropionate%" OR LOWER(tradeNames_... | [{'UUID': 'DrugTargetsIndication121923_text_220897', 'drugName': 'Betamethasone Dipropionate', 'tradeNames_list': "['Alphatrex', 'Betamethasone dipropionate', 'Diprolene', 'Diprolene afDiprosone', 'Sernivo']", 'syns_list': "['Betamethasone (as dipropionate)', 'Betamethasone 17,21-dipropionateBetamethasone dipropionate'... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.560 | Q6 | What genes does Gemcitabine Hydrochloride target when it's used to treat cervical cancer? | Gemcitabine Hydrochloride has not been approved by the FDA as a treatment for cervical cancer, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are POLA1, POLD4, POLD3, POLD1, POLD2, POLE, POLA2, PRIM1, PRIM2, POLE2, POLE3, RRM1, RRM2B, and RRM2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%gemcitabine hydrochloride%" OR LOWER(tradeNames_l... | [{'UUID': 'DrugTargetsIndication121923_text_756063', 'drugName': 'Gemcitabine Hydrochloride', 'tradeNames_list': "['Gemcitabine hydrochloride', 'Gemzar', 'Infugem']", 'syns_list': "['Gemcitabine (as hydrochloride)', 'Gemcitabine hclGemcitabine hydrochloride', 'Gemzar', 'LY-188011LY-188011 HYDROCHLORIDE', 'LY188011 HYDR... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.44 | Q6 | What genes does Prednisone target when it's used to treat ophthalmic herpes zoster? | When used to treat ophthalmic herpes zoster, the drug Prednisone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%prednisone%" OR LOWER(tradeNames_list) LIKE "%pre... | [{'UUID': 'DrugTargetsIndication121923_text_218695', 'drugName': 'Prednisone', 'tradeNames_list': "['Cortan', 'Cortancyl', 'Decortisyl', 'Delta-dome', 'Deltasone', 'FernisoneLiquid pred', 'Lodotra', 'Meticorten', 'Orasone', 'Paracort', 'Prednicen-mPrednisone', 'Prednisone intensol', 'Rayos', 'Servisone', 'Sterapred']",... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.278 | Q6 | What genes does Rufinamide target when it's used to treat Lennox-Gastaut syndrome? | When used to treat Lennox-Gastaut syndrome, the drug Rufinamide targets the genes SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%rufinamide%" OR LOWER(tradeNames_list) LIKE "%ruf... | [{'UUID': 'DrugTargetsIndication121923_text_652675', 'drugName': 'Rufinamide', 'tradeNames_list': "['Banzel', 'Inovelon', 'Rufinamide']", 'syns_list': "['60231/4', 'CGP 33101', 'CGP-33101', 'E-2080', 'E2080', 'RUF 331', 'RUF-331Rufinamide']", 'target': 'ENSG00000144285', 'approvedSymbol': 'SCN1A', 'approvedName': 'sodi... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1096 | Q6 | What genes does Budesonide target when it's used to treat sinusitis? | Budesonide has not been approved by the FDA as a treatment for sinusitis, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%budesonide%" OR LOWER(tradeNames_list) LIKE "%bud... | [{'UUID': 'DrugTargetsIndication121923_text_222599', 'drugName': 'Budesonide', 'tradeNames_list': "['Aircort', 'Budeflam aquanase', 'Budelin novolizer', 'BudenofalkBudesonide', 'Cortiment', 'Duoresp spiromax', 'Entocort', 'Entocort crEntocort ec', 'Ortikos', 'Preferid', 'Pulmaxan', 'PulmicortPulmicort flexhaler', 'Pulm... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.104 | Q6 | What genes does Aspirin target when it's used to treat Myalgia? | When used to treat Myalgia, the drug Aspirin targets the genes PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%aspirin%" OR LOWER(tradeNames_list) LIKE "%aspiri... | [{'UUID': 'DrugTargetsIndication121923_text_834426', 'drugName': 'Aspirin', 'tradeNames_list': "['8-hour bayer', 'Acetosalic Acid', 'Acetylsalic acidAcetylsalicylic Acid', 'Alka rapid', 'Anadin all night', 'Angettes 75Aspirin', 'Aspro clr', 'Bayer extra strength aspirin for migraine painDanamep', 'Disprin cv', 'Disprin... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.856 | Q6 | What genes does Fedratinib Hydrochloride target when it's used to treat primary myelofibrosis? | When used to treat primary myelofibrosis, the drug Fedratinib Hydrochloride targets the genes FLT3 and JAK2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fedratinib hydrochloride%" OR LOWER(tradeNames_li... | [{'UUID': 'DrugTargetsIndication121923_text_933946', 'drugName': 'Fedratinib Hydrochloride', 'tradeNames_list': "['Inrebic']", 'syns_list': "['Fedratinib hydrochloride', 'SAR302503A']", 'target': 'ENSG00000122025', 'approvedSymbol': 'FLT3', 'approvedName': 'fms related receptor tyrosine kinase 3', 'mesh_heading': 'Prim... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.985 | Q6 | What genes does Fluticasone Furoate target when it's used to treat asthma? | When used to treat asthma, the drug Fluticasone Furoate targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fluticasone furoate%" OR LOWER(tradeNames_list) L... | [{'UUID': 'DrugTargetsIndication121923_text_225663', 'drugName': 'Fluticasone Furoate', 'tradeNames_list': "['Arnuity ellipta', 'Avamys', 'Flonase sensimist allergy reliefRelvar ellipta', 'Trelegy ellipta', 'Veramyst']", 'syns_list': "['Allermist', 'Ennhale', 'Fluticasone furoate', 'Furamist', 'GSK 685 698GSK-685968', ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.948 | Q6 | What genes does Mesalamine target when it's used to treat colorectal carcinoma? | Mesalamine has not been approved by the FDA as a treatment for colorectal carcinoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are PTGS2, PTGS1, PPARG, and ALOX5. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%mesalamine%" OR LOWER(tradeNames_list) LIKE "%mes... | [{'UUID': 'DrugTargetsIndication121923_text_842706', 'drugName': 'Mesalamine', 'tradeNames_list': "['Apriso', 'Asacol', 'Asacol hd', 'Canasa', 'Coltec ec', 'Delzicol', 'IpocolLialda', 'Mesalamine', 'Mesren mr', 'Mezavant xl', 'Octasa', 'PentasaPentasa sr', 'Rowasa', 'Salofalk', 'Sfrowasa']", 'syns_list': "['Benzoic aci... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.110 | Q6 | What genes does Dutetrabenazine target when it's used to treat Huntington disease? | When used to treat Huntington disease, the drug Dutetrabenazine targets the gene SLC18A2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dutetrabenazine%" OR LOWER(tradeNames_list) LIKE ... | [{'UUID': 'DrugTargetsIndication121923_text_938617', 'drugName': 'Dutetrabenazine', 'tradeNames_list': "['Austedo']", 'syns_list': "['Deutetrabenazine', 'Dutetrabenazine', 'SD-809']", 'target': 'ENSG00000165646', 'approvedSymbol': 'SLC18A2', 'approvedName': 'solute carrier family 18 member A2', 'mesh_heading': 'Hunting... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1296 | Q6 | What genes does Megestrol Acetate target when it's used to treat inborn errors of immunity? | When used to treat inborn errors of immunity, the drug Megestrol Acetate targets the gene PGR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%megestrol acetate%" OR LOWER(tradeNames_list) LIK... | [{'UUID': 'DrugTargetsIndication121923_text_940579', 'drugName': 'Megestrol Acetate', 'tradeNames_list': "['Megace', 'Megace es', 'Megestrol acetate', 'Ovaban']", 'syns_list': "['5071', 'BDH 1298', 'BDH-1298', 'Chronopil', 'Megesterol acetate', 'MegestrolMegestrol 17.alpha.-acetate', 'Megestrol acetate', 'NSC-71423', '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.503 | Q6 | What genes does Eteplirsen target when it's used to treat Duchenne muscular dystrophy? | When used to treat Duchenne muscular dystrophy, the drug Eteplirsen targets the gene DMD. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%eteplirsen%" OR LOWER(tradeNames_list) LIKE "%ete... | [{'UUID': 'DrugTargetsIndication121923_text_1100458', 'drugName': 'Eteplirsen', 'tradeNames_list': "['Exondys 51']", 'syns_list': "['AVI-4658', 'Eteplirsen']", 'target': 'ENSG00000198947', 'approvedSymbol': 'DMD', 'approvedName': 'dystrophin', 'mesh_heading': 'Muscular Dystrophy, Duchenne', 'efo_term': 'Duchenne muscul... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1981 | Q6 | What genes does Estradiol Acetate target when it's used to treat menopause? | When used to treat menopause, the drug Estradiol Acetate targets the gene ESR1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%estradiol acetate%" OR LOWER(tradeNames_list) LIK... | [{'UUID': 'DrugTargetsIndication121923_text_823877', 'drugName': 'Estradiol Acetate', 'tradeNames_list': "['Femring', 'Femtrace']", 'syns_list': "['E3A', 'ESTRADIOL-3-ACETATE', 'Estradiol 3-acetate', 'Estradiol acetate']", 'target': 'ENSG00000091831', 'approvedSymbol': 'ESR1', 'approvedName': 'estrogen receptor 1', 'me... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.869 | Q6 | What genes does Alvimopan target when it's used to treat Constipation? | When used to treat Constipation, the drug Alvimopan targets the gene OPRM1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%alvimopan%" OR LOWER(tradeNames_list) LIKE "%alvi... | [{'UUID': 'DrugTargetsIndication121923_text_766793', 'drugName': 'Alvimopan', 'tradeNames_list': "['Entereg']", 'syns_list': "['ADL 8-2698', 'ADL-8-2698', 'Alvimopan', 'Alvimopan anhydrousAlvimopan dihydrate', 'Anhydrous alvimopan', 'LY-246736LY-246736 DIHYDRATE', 'LY246736']", 'target': 'ENSG00000112038', 'approvedSym... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.748 | Q6 | What genes does Sorafenib target when it's used to treat renal cell carcinoma? | When used to treat renal cell carcinoma, the drug Sorafenib targets the genes KDR, BRAF, FLT1, FLT3, KIT, FLT4, PDGFRB, RAF1, and RET. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%sorafenib%" OR LOWER(tradeNames_list) LIKE "%sora... | [{'UUID': 'DrugTargetsIndication121923_text_683296', 'drugName': 'Sorafenib Tosylate', 'tradeNames_list': "['Nexavar']", 'syns_list': "['BAY 54-9085', 'BAY-54-9085', 'Sorafenib tosilate', 'Sorafenib tosylate']", 'target': 'ENSG00000128052', 'approvedSymbol': 'KDR', 'approvedName': 'kinase insert domain receptor', 'mesh... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1015 | Q6 | What genes does Fluticasone Propionate target when it's used to treat Nasal Cavity Polyp? | When used to treat Nasal Cavity Polyp, the drug Fluticasone Propionate targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fluticasone propionate%" OR LOWER(tradeNames_list... | [{'UUID': 'DrugTargetsIndication121923_text_232535', 'drugName': 'Fluticasone Propionate', 'tradeNames_list': "['Aerivio spiromax', 'Airflusal forspiro', 'Armonair digihalerArmonair respiclick', 'Cutivate', 'Flixonase', 'Flixotide', 'FlonaseFlonase allergy relief', 'Flovent', 'Flovent diskus 100Flovent diskus 250', 'Fl... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1315 | Q6 | What genes does Hydromorphone Hydrochloride target when it's used to treat drug dependence? | When used to treat drug dependence, the drug Hydromorphone Hydrochloride targets the gene OPRM1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%hydromorphone hydrochloride%" OR LOWER(tradeNames... | [{'UUID': 'DrugTargetsIndication121923_text_792050', 'drugName': 'Hydromorphone Hydrochloride', 'tradeNames_list': "['Dilaudid', 'Dilaudid-hp', 'Exalgo', 'Hydromorphone hydrochloridePalladone', 'Palladone-sr']", 'syns_list': "['Dihydromorphinone hydrochloride', 'Hydromorphone HCl', 'Hydromorphone hclHydromorphone hydro... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1297 | Q6 | What genes does Cabozantinib S-Malate target when it's used to treat thyroid cancer? | When used to treat thyroid cancer, the drug Cabozantinib S-Malate targets the genes KDR and MET. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%cabozantinib s-malate%" OR LOWER(tradeNames_list)... | [{'UUID': 'DrugTargetsIndication121923_text_669676', 'drugName': 'Cabozantinib S-Malate', 'tradeNames_list': "['Cabometyx', 'Cometriq']", 'syns_list': "['BMS-907351', 'Cabozantinib malate', 'Cabozantinib s-malate', 'XL-184XL184']", 'target': 'ENSG00000128052', 'approvedSymbol': 'KDR', 'approvedName': 'kinase insert dom... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.609 | Q6 | What genes does Acetaminophen target when it's used to treat Headache? | When used to treat Headache, the drug Acetaminophen targets the genes PTGS2, PTGS1, TRPV1, and FAAH. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%acetaminophen%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_830307', 'drugName': 'Acetaminophen', 'tradeNames_list': '[\'Abdine\', \'Acephen\', \'Acetaminophen\', \'Alvedon\', \'Angiers\', \'CalpolCalpol six plus\', \'Calpol six plus fastmelts\', \'Child lemsip\', \'CupanolDafalgan\', \'Datril\', \'Disprol\', \'Disprol infant\', \'Dis... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1362 | Q6 | What genes does Budesonide target when it's used to treat Airway obstruction? | When used to treat Airway obstruction, the drug Budesonide targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%budesonide%" OR LOWER(tradeNames_list) LIKE "%bud... | [{'UUID': 'DrugTargetsIndication121923_text_222610', 'drugName': 'Budesonide', 'tradeNames_list': "['Aircort', 'Budeflam aquanase', 'Budelin novolizer', 'BudenofalkBudesonide', 'Cortiment', 'Duoresp spiromax', 'Entocort', 'Entocort crEntocort ec', 'Ortikos', 'Preferid', 'Pulmaxan', 'PulmicortPulmicort flexhaler', 'Pulm... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.75 | Q6 | What genes does Buprenorphine target when it's used to treat opioid use disorder? | When used to treat opioid use disorder, the drug Buprenorphine targets the genes OPRM1 and OPRK1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%buprenorphine%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_764198', 'drugName': 'Buprenorphine', 'tradeNames_list': "['Bupeaze', 'Buplast', 'Butec', 'Butrans', 'Hapoctasin', 'Panitaz', 'PrenotrixReletrans', 'Sevodyne', 'Sublocade', 'Temgesic', 'Tephine', 'Transtec']", 'syns_list': "['ALKS-5461 COMPONENT BUPRENORPHINE', 'Brixadi', 'Bu... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1082 | Q6 | What genes does Fluorouracil target when it's used to treat keratosis? | When used to treat keratosis, the drug Fluorouracil targets the gene TYMS. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fluorouracil%" OR LOWER(tradeNames_list) LIKE "%f... | [{'UUID': 'DrugTargetsIndication121923_text_919465', 'drugName': 'Fluorouracil', 'tradeNames_list': "['5.f.u.', 'Accusite', 'Actikerall', 'Adrucil', 'Carac', 'Efudex', 'EfudixFluoro-uracil roche', 'Fluoroplex', 'Fluorouracil', 'Tolak']", 'syns_list': "['5 FU', '5-FU', '5-Fluorouracil', '5-fluoruracil', 'FluorouracilFlu... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1214 | Q6 | What genes does Celecoxib target when it's used to treat cancer? | When used to treat cancer, the drug Celecoxib targets the gene PTGS2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%celecoxib%" OR LOWER(tradeNames_list) LIKE "%cele... | [{'UUID': 'DrugTargetsIndication121923_text_833492', 'drugName': 'Celecoxib', 'tradeNames_list': "['Celebra', 'Celebrex', 'Celecoxib', 'Elyxyb', 'Onsenal']", 'syns_list': "['Celecoxib', 'DFN-15', 'DFN15', 'NSC-719627', 'NSC-758624', 'SC-58635']", 'target': 'ENSG00000073756', 'approvedSymbol': 'PTGS2', 'approvedName': '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1167 | Q6 | What genes does Dexamethasone target when it's used to treat tenosynovitis? | When used to treat tenosynovitis, the drug Dexamethasone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dexamethasone%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_227797', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.625 | Q6 | What genes does Ticagrelor target when it's used to treat internal carotid artery stenosis? | Ticagrelor has not been approved by the FDA as a treatment for internal carotid artery stenosis, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is P2RY12. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ticagrelor%" OR LOWER(tradeNames_list) LIKE "%tic... | [{'UUID': 'DrugTargetsIndication121923_text_920450', 'drugName': 'Ticagrelor', 'tradeNames_list': "['Brilinta', 'Brilique']", 'syns_list': "['AR-C126532XX', 'AZD-6140', 'AZD6140', 'Possia', 'Ticagrelor']", 'target': 'ENSG00000169313', 'approvedSymbol': 'P2RY12', 'approvedName': 'purinergic receptor P2Y12', 'mesh_headin... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.487 | Q6 | What genes does Dexamethasone target when it's used to treat Crohn's disease? | When used to treat Crohn's disease, the drug Dexamethasone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dexamethasone%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_227747', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1579 | Q6 | What genes does Bupivacaine target when it's used to treat osteoarthritis? | Bupivacaine has not been approved by the FDA as a treatment for osteoarthritis, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is SCN4A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%bupivacaine%" OR LOWER(tradeNames_list) LIKE "%bu... | [{'UUID': 'DrugTargetsIndication121923_text_663602', 'drugName': 'Bupivacaine', 'tradeNames_list': "['Anekain', 'Exparel', 'Marcaine', 'Posimir', 'Sensorcaine']", 'syns_list': "['Bucaine', 'Bupivacaine', 'Bupivacaine liposome', 'LIQ-865', 'LIQ865Liposomal bupivacaine', 'MarcaineRopivacaine hydrochloride impurity, bupiv... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.512 | Q6 | What genes does Cenobamate target when it's used to treat Focal-onset seizure? | When used to treat Focal-onset seizure, the drug Cenobamate targets the genes SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, SCN10A, GABRA1, GABRB2, GABRG2, GABRB3, GABRA4, GABRG3, GABRQ, GABRA3, GABRP, GABRD, GABRG1, GABRB1, GABRE, GABRA2, GABRA5, and GABRA6. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%cenobamate%" OR LOWER(tradeNames_list) LIKE "%cen... | [{'UUID': 'DrugTargetsIndication121923_text_456025', 'drugName': 'Cenobamate', 'tradeNames_list': "['Xcopri']", 'syns_list': "['Cenobamate', 'YKP-3089', 'YKP3089']", 'target': 'ENSG00000144285', 'approvedSymbol': 'SCN1A', 'approvedName': 'sodium voltage-gated channel alpha subunit 1', 'mesh_heading': 'Seizures', 'efo_t... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.740 | Q6 | What genes does Infigratinib Phosphate target when it's used to treat cholangiocarcinoma? | When used to treat cholangiocarcinoma, the drug Infigratinib Phosphate targets the genes FGFR1, FGFR3, FGFR2, and FGFR4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%infigratinib phosphate%" OR LOWER(tradeNames_list... | [{'UUID': 'DrugTargetsIndication121923_text_708623', 'drugName': 'Infigratinib Phosphate', 'tradeNames_list': "['Truseltiq']", 'syns_list': "['BGJ-398 phosphate', 'Infigratinib monophosphate', 'Infigratinib phosphate']", 'target': 'ENSG00000077782', 'approvedSymbol': 'FGFR1', 'approvedName': 'fibroblast growth factor r... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.762 | Q6 | What genes does Pacritinib Citrate target when it's used to treat primary myelofibrosis? | When used to treat primary myelofibrosis, the drug Pacritinib Citrate targets the genes FLT3 and JAK2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%pacritinib citrate%" OR LOWER(tradeNames_list) LI... | [{'UUID': 'DrugTargetsIndication121923_text_933972', 'drugName': 'Pacritinib Citrate', 'tradeNames_list': "['Vonjo']", 'syns_list': "['Pacritinib citrate']", 'target': 'ENSG00000122025', 'approvedSymbol': 'FLT3', 'approvedName': 'fms related receptor tyrosine kinase 3', 'mesh_heading': 'Primary Myelofibrosis', 'efo_ter... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1990 | Q6 | What genes does Axitinib target when it's used to treat papillary renal cell carcinoma? | When used to treat papillary renal cell carcinoma, the drug Axitinib targets the genes KDR, FLT1, and FLT4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%axitinib%" OR LOWER(tradeNames_list) LIKE "%axiti... | [{'UUID': 'DrugTargetsIndication121923_text_689366', 'drugName': 'Axitinib', 'tradeNames_list': "['Inlyta']", 'syns_list': "['AG-013736', 'AG-13736', 'Axitinib', 'NSC-757441']", 'target': 'ENSG00000128052', 'approvedSymbol': 'KDR', 'approvedName': 'kinase insert domain receptor', 'mesh_heading': 'Carcinoma, Renal Cell'... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.784 | Q6 | What genes does Asenapine target when it's used to treat psychosis? | When used to treat psychosis, the drug Asenapine targets the genes DRD2 and HTR2A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%asenapine%" OR LOWER(tradeNames_list) LIKE "%asen... | [{'UUID': 'DrugTargetsIndication121923_text_197844', 'drugName': 'Asenapine', 'tradeNames_list': "['Secuado', 'Sycrest']", 'syns_list': "['Asenapine']", 'target': 'ENSG00000149295', 'approvedSymbol': 'DRD2', 'approvedName': 'dopamine receptor D2', 'mesh_heading': 'Psychotic Disorders', 'efo_term': 'psychosis', 'yearOfF... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1763 | Q6 | What genes does Ambrisentan target when it's used to treat hypertension? | When used to treat hypertension, the drug Ambrisentan targets the genes EDNRA and EDNRB. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ambrisentan%" OR LOWER(tradeNames_list) LIKE "%am... | [{'UUID': 'DrugTargetsIndication121923_text_1084059', 'drugName': 'Ambrisentan', 'tradeNames_list': "['Letairis', 'Volibris']", 'syns_list': "['Ambrisentan', 'GSK-1325760', 'GSK-1325760A', 'GSK1325760', 'GSK1325760ALU-208075']", 'target': 'ENSG00000151617', 'approvedSymbol': 'EDNRA', 'approvedName': 'endothelin recepto... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.848 | Q6 | What genes does Spironolactone target when it's used to treat diastolic heart failure? | Spironolactone has not been approved by the FDA as a treatment for diastolic heart failure, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is NR3C2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%spironolactone%" OR LOWER(tradeNames_list) LIKE "... | [{'UUID': 'DrugTargetsIndication121923_text_1094534', 'drugName': 'Spironolactone', 'tradeNames_list': "['Abbolactone', 'Aldactone', 'Carospir', 'Diatensec', 'Gx spironolLaractone', 'Spiretic', 'Spiroctan 100', 'Spiroctan 25', 'Spiroctan 50Spironolactone', 'Spirospare 100', 'Spirospare 25']", 'syns_list': "['NSC-150399... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.315 | Q6 | What genes does Abemaciclib target when it's used to treat neoplasm? | When used to treat neoplasm, the drug Abemaciclib targets the genes CDK4 and CDK6. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%abemaciclib%" OR LOWER(tradeNames_list) LIKE "%ab... | [{'UUID': 'DrugTargetsIndication121923_text_849807', 'drugName': 'Abemaciclib', 'tradeNames_list': "['Verzenio', 'Verzenios']", 'syns_list': "['Abemaciclib', 'LY-2835219', 'LY2835219', 'Ly-2835219']", 'target': 'ENSG00000135446', 'approvedSymbol': 'CDK4', 'approvedName': 'cyclin dependent kinase 4', 'mesh_heading': 'Br... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.816 | Q6 | What genes does Amifampridine Phosphate target when it's used to treat Myasthenia gravis? | When used to treat Myasthenia gravis, the drug Amifampridine Phosphate targets the genes KCNQ1, KCND3, KCNH2, KCNA2, KCNA1, KCNQ2, KCNQ3, KCNA7, KCNQ5, KCNQ4, KCNH1, KCNA4, KCNA5, KCNA3, KCNA6, KCNC1, KCND2, KCNB2, KCNC4, KCNC3, KCNB1, KCNA10, KCNV1, KCNH5, KCNG3, KCNG4, KCNV2, KCNS1, KCNH8, KCNC2, KCNS3, KCNH6, KCNF1,... | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%amifampridine phosphate%" OR LOWER(tradeNames_lis... | [{'UUID': 'DrugTargetsIndication121923_text_968758', 'drugName': 'Amifampridine Phosphate', 'tradeNames_list': "['Firdapse']", 'syns_list': "['3,4-DAPP', 'Amifampridine phosphate', 'DAPP', 'Zenas']", 'target': 'ENSG00000177272', 'approvedSymbol': 'KCNA3', 'approvedName': 'potassium voltage-gated channel subfamily A mem... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.411 | Q6 | What genes does Capsaicin target when it's used to treat arthritis? | When used to treat arthritis, the drug Capsaicin targets the gene TRPV1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%capsaicin%" OR LOWER(tradeNames_list) LIKE "%caps... | [{'UUID': 'DrugTargetsIndication121923_text_993158', 'drugName': 'Capsaicin', 'tradeNames_list': "['Qutenza', 'Zacin', 'Zostrix', 'Zostrix hp']", 'syns_list': "['ALGRX 4975', 'ALGRX-4975', 'Ausanil', 'Axsain', 'Capsaicin', 'Capzasin-hpCntx-4975', 'Dolenon', 'FEMA NO. 3404', 'Mioton', 'NGX-1998', 'NGX-4010NSC-56353', 'N... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.826 | Q6 | What genes does Budesonide target when it's used to treat seasonal allergic rhinitis? | When used to treat seasonal allergic rhinitis, the drug Budesonide targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%budesonide%" OR LOWER(tradeNames_list) LIKE "%bud... | [{'UUID': 'DrugTargetsIndication121923_text_222615', 'drugName': 'Budesonide', 'tradeNames_list': "['Aircort', 'Budeflam aquanase', 'Budelin novolizer', 'BudenofalkBudesonide', 'Cortiment', 'Duoresp spiromax', 'Entocort', 'Entocort crEntocort ec', 'Ortikos', 'Preferid', 'Pulmaxan', 'PulmicortPulmicort flexhaler', 'Pulm... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1143 | Q6 | What genes does Clobazam target when it's used to treat Seizure? | When used to treat Seizure, the drug Clobazam targets the genes GABRA1, GABRB2, GABRG2, GABRB3, GABRA4, GABRG3, GABRQ, GABRA3, GABRP, GABRD, GABRG1, GABRB1, GABRE, GABRA2, GABRA5, and GABRA6. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%clobazam%" OR LOWER(tradeNames_list) LIKE "%cloba... | [{'UUID': 'DrugTargetsIndication121923_text_947358', 'drugName': 'Clobazam', 'tradeNames_list': "['Frisium', 'Onfi', 'Perizam', 'Sympazan', 'Tapclob', 'Urbanyl']", 'syns_list': "['Clobazam', 'Colbazam', 'H 4723', 'H-4723', 'HR 376', 'HR-376', 'LM 2717LM-2717', 'Mystan', 'NSC-336279', 'Urbadan']", 'target': 'ENSG0000002... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.313 | Q6 | What genes does Hydroxyprogesterone Caproate target when it's used to treat premature birth? | When used to treat premature birth, the drug Hydroxyprogesterone Caproate targets the gene PGR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%hydroxyprogesterone caproate%" OR LOWER(tradeName... | [{'UUID': 'DrugTargetsIndication121923_text_940462', 'drugName': 'Hydroxyprogesterone Caproate', 'tradeNames_list': "['Delalutin', 'Hydroxyprogesterone caproate', 'MakenaMakena (autoinjector)', 'Makena preservative free', 'Proluton depot']", 'syns_list': "['17-ohpc', '17.alpha.-caproyloxy-p4', 'Depo-proluton', 'Hormofo... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.229 | Q6 | What genes does Imiquimod target when it's used to treat cirrhosis of liver? | Imiquimod has not been approved by the FDA as a treatment for cirrhosis of liver, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is TLR7. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%imiquimod%" OR LOWER(tradeNames_list) LIKE "%imiq... | [{'UUID': 'DrugTargetsIndication121923_text_919754', 'drugName': 'Imiquimod', 'tradeNames_list': "['Aldara', 'Imiquimod', 'Zyclara']", 'syns_list': "['Aldara', 'Imiquimod', 'NSC-369100', 'NSC-759651', 'R-837', 'S-26308', 'S26308Tmx-101']", 'target': 'ENSG00000196664', 'approvedSymbol': 'TLR7', 'approvedName': 'toll lik... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1699 | Q6 | What genes does Dexamethasone target when it's used to treat meningeal tuberculosis? | When used to treat meningeal tuberculosis, the drug Dexamethasone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dexamethasone%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_227783', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1451 | Q6 | What genes does Meloxicam target when it's used to treat Dysmenorrhea? | Meloxicam has not been approved by the FDA as a treatment for Dysmenorrhea, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is PTGS2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%meloxicam%" OR LOWER(tradeNames_list) LIKE "%melo... | [{'UUID': 'DrugTargetsIndication121923_text_842363', 'drugName': 'Meloxicam', 'tradeNames_list': "['Anjeso', 'Meloxicam', 'Mobic', 'Qmiiz odt', 'Vivlodex']", 'syns_list': "['Acticam', 'Contacera', 'Coxicam', 'Emdocam', 'Flexicam', 'Inflacam', 'LoxicomMelfax', 'Melosus', 'Melovem', 'Meloxicam', 'Meloxidolor', 'Meloxidyl... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1976 | Q6 | What genes does Pemetrexed Disodium target when it's used to treat Thymic Carcinoma? | Pemetrexed Disodium has not been approved by the FDA as a treatment for Thymic Carcinoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are TYMS, GART, and DHFR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%pemetrexed disodium%" OR LOWER(tradeNames_list) L... | [{'UUID': 'DrugTargetsIndication121923_text_918398', 'drugName': 'Pemetrexed Disodium', 'tradeNames_list': "['Alimta']", 'syns_list': "['LY-231514 DISODIUM SALT', 'LY231514 DISODIUM SALT', 'Pemetrexed disodiumPemetrexed disodium heptahydrate', 'Pemetrexed sodium hydratePemetrexed sodium salt']", 'target': 'ENSG00000228... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.814 | Q6 | What genes does Vosoritide target when it's used to treat bone disease? | When used to treat bone disease, the drug Vosoritide targets the gene NPR2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%vosoritide%" OR LOWER(tradeNames_list) LIKE "%vos... | [{'UUID': 'DrugTargetsIndication121923_text_1192675', 'drugName': 'Vosoritide', 'tradeNames_list': "['Voxzogo']", 'syns_list': "['BMN 111', 'BMN-111', 'Bmn 111', 'Vosoritide', 'Voxzogo']", 'target': 'ENSG00000159899', 'approvedSymbol': 'NPR2', 'approvedName': 'natriuretic peptide receptor 2', 'mesh_heading': 'Bone Dise... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1847 | Q6 | What genes does Tafamidis target when it's used to treat cardiomyopathy? | When used to treat cardiomyopathy, the drug Tafamidis targets the gene TTR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%tafamidis%" OR LOWER(tradeNames_list) LIKE "%tafa... | [{'UUID': 'DrugTargetsIndication121923_text_1097615', 'drugName': 'Tafamidis', 'tradeNames_list': "['Vyndamax', 'Vyndaqel']", 'syns_list': "['FX-1005', 'FX-1006', 'FX1006', 'Tafamidis']", 'target': 'ENSG00000118271', 'approvedSymbol': 'TTR', 'approvedName': 'transthyretin', 'mesh_heading': 'Cardiomyopathies', 'efo_term... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.151 | Q6 | What genes does Sirolimus target when it's used to treat Autosomal dominant polycystic kidney disease? | Sirolimus has not been approved by the FDA as a treatment for Autosomal dominant polycystic kidney disease, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is FKBP1A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%sirolimus%" OR LOWER(tradeNames_list) LIKE "%siro... | [{'UUID': 'DrugTargetsIndication121923_text_1084553', 'drugName': 'Sirolimus', 'tradeNames_list': "['Fyarro', 'Hyftor', 'Rapamune', 'Sirolimus']", 'syns_list': "['AY-22989', 'Fyarro', 'Hyftor', 'L04AA10', 'NSC-226080', 'Npc-12g', 'RapalimusRapamycin', 'SM-88 COMPONENT SIROLIMUS', 'Sirolimus', 'WY-090217']", 'target': '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.781 | Q6 | What genes does Pemigatinib target when it's used to treat cancer? | When used to treat cancer, the drug Pemigatinib targets the genes FGFR1, FGFR3, and FGFR2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%pemigatinib%" OR LOWER(tradeNames_list) LIKE "%pe... | [{'UUID': 'DrugTargetsIndication121923_text_706910', 'drugName': 'Pemigatinib', 'tradeNames_list': "['Pemazyre']", 'syns_list': "['Fgfr inhibitor incb054828', 'INCB054828', 'Incb-054828', 'Incb054828Pemigatinib']", 'target': 'ENSG00000077782', 'approvedSymbol': 'FGFR1', 'approvedName': 'fibroblast growth factor recepto... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.727 | Q6 | What genes does Lorlatinib target when it's used to treat cancer? | When used to treat cancer, the drug Lorlatinib targets the genes ALK and EML4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lorlatinib%" OR LOWER(tradeNames_list) LIKE "%lor... | [{'UUID': 'DrugTargetsIndication121923_text_991068', 'drugName': 'Lorlatinib', 'tradeNames_list': "['Lorbrena']", 'syns_list': "['Lorlatinib', 'PF-06463922']", 'target': 'ENSG00000171094', 'approvedSymbol': 'ALK', 'approvedName': 'ALK receptor tyrosine kinase', 'mesh_heading': 'Neoplasms', 'efo_term': 'cancer', 'yearOf... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.820 | Q6 | What genes does Maralixibat Chloride target when it's used to treat Pruritus? | When used to treat Pruritus, the drug Maralixibat Chloride targets the gene SLC10A2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%maralixibat chloride%" OR LOWER(tradeNames_list) ... | [{'UUID': 'DrugTargetsIndication121923_text_992696', 'drugName': 'Maralixibat Chloride', 'tradeNames_list': "['Livmarli']", 'syns_list': "['LUM-001', 'LUM001', 'Lopixibat chloride', 'Maralixibat chloride']", 'target': 'ENSG00000125255', 'approvedSymbol': 'SLC10A2', 'approvedName': 'solute carrier family 10 member 2', '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
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