uuid stringlengths 4 8 | template_uuid stringclasses 40
values | question stringlengths 13 193 | answer stringlengths 29 2.2k | benchmark_query stringlengths 133 622 | execution_results stringlengths 2 1.14M | query_type stringclasses 2
values | sql_category stringclasses 26
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Q6.1636 | Q6 | What genes does Cetirizine Hydrochloride target when it's used to treat urticaria? | When used to treat urticaria, the drug Cetirizine Hydrochloride targets the gene HRH1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%cetirizine hydrochloride%" OR LOWER(tradeNames_li... | [{'UUID': 'DrugTargetsIndication121923_text_455820', 'drugName': 'Cetirizine Hydrochloride', 'tradeNames_list': '[\'Allacan\', \'Allertek\', \'Becoallergy\', \'Cetec\', \'Cetirizine hydrochlorideCetirizine hydrochloride allergy\', \'Cetirizine hydrochloride hivesCetirizine hydrochloride hives relief\', "CetirocolChildr... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.825 | Q6 | What genes does Osimertinib target when it's used to treat non-small cell lung carcinoma? | When used to treat non-small cell lung carcinoma, the drug Osimertinib targets the gene EGFR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%osimertinib%" OR LOWER(tradeNames_list) LIKE "%os... | [{'UUID': 'DrugTargetsIndication121923_text_217149', 'drugName': 'Osimertinib Mesylate', 'tradeNames_list': "['Tagrisso']", 'syns_list': "['AZD-9291 MESYLATE', 'AZD9291 mesylate', 'Mereletinib mesilateMereletinib mesylate', 'Osimertinib mesilate', 'Osimertinib mesylate']", 'target': 'ENSG00000146648', 'approvedSymbol':... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.581 | Q6 | What genes does Apixaban target when it's used to treat atrial fibrillation? | When used to treat atrial fibrillation, the drug Apixaban targets the gene F10. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%apixaban%" OR LOWER(tradeNames_list) LIKE "%apixa... | [{'UUID': 'DrugTargetsIndication121923_text_710506', 'drugName': 'Apixaban', 'tradeNames_list': "['Eliquis']", 'syns_list': "['Apixaban', 'BMS-562247', 'BMS-562247-01']", 'target': 'ENSG00000126218', 'approvedSymbol': 'F10', 'approvedName': 'coagulation factor X', 'mesh_heading': 'Atrial Fibrillation', 'efo_term': 'atr... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.563 | Q6 | What genes does Tacrolimus target when it's used to treat immune system disease? | When used to treat immune system disease, the drug Tacrolimus targets the gene FKBP1A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%tacrolimus%" OR LOWER(tradeNames_list) LIKE "%tac... | [{'UUID': 'DrugTargetsIndication121923_text_1091477', 'drugName': 'Tacrolimus', 'tradeNames_list': "['Adoport', 'Advagraf', 'Astagraf xl', 'Capexion', 'Envarsus', 'Envarsus xrModigraf', 'Perixis', 'Prograf', 'Protopic', 'Tacni', 'Tacrolimus', 'Vivadex']", 'syns_list': "['FK 506', 'FR900506', 'Tacrolimus', 'Tacrolimus h... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1758 | Q6 | What genes does Pemetrexed target when it's used to treat cancer? | When used to treat cancer, the drug Pemetrexed targets the genes TYMS, GART, and DHFR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%pemetrexed%" OR LOWER(tradeNames_list) LIKE "%pem... | [{'UUID': 'DrugTargetsIndication121923_text_918729', 'drugName': 'Pemetrexed', 'tradeNames_list': "['Alimta', 'Pemfexy']", 'syns_list': "['LY-2315', 'LY-231514', 'LY231514', 'NSC-698037', 'Pemetrexed']", 'target': 'ENSG00000176890', 'approvedSymbol': 'TYMS', 'approvedName': 'thymidylate synthetase', 'mesh_heading': 'Ne... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1727 | Q6 | What genes does Selumetinib Sulfate target when it's used to treat neurofibromatosis type 1? | When used to treat neurofibromatosis type 1, the drug Selumetinib Sulfate targets the genes MAP2K2 and MAP2K1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%selumetinib sulfate%" OR LOWER(tradeNames_list) L... | [{'UUID': 'DrugTargetsIndication121923_text_932837', 'drugName': 'Selumetinib Sulfate', 'tradeNames_list': "['Koselugo']", 'syns_list': "['AZD-6244 HYD-SULFATE', 'AZD-6244 HYDROGEN SULFATE', 'AZD6244 HYD-SULFATEAZD6244 HYDROGEN SULFATE', 'Azd-6244 hydrogen sulphateAzd6244 hydrogen sulphate', 'Selumetinib sulfate', 'Sel... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1349 | Q6 | What genes does Fenofibrate target when it's used to treat diabetes mellitus? | When used to treat diabetes mellitus, the drug Fenofibrate targets the gene PPARA. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fenofibrate%" OR LOWER(tradeNames_list) LIKE "%fe... | [{'UUID': 'DrugTargetsIndication121923_text_243843', 'drugName': 'Fenofibric Acid', 'tradeNames_list': "['Fenocor-67', 'Fenogal', 'Fibricor', 'Lipanthyl', 'Lipofen', 'LofibraSupralip', 'Trilipix']", 'syns_list': "['Fenofibrate free acid', 'Fenofibrate related compound bFenofibric acid', 'LF-153', 'NSC-281318', 'Proceto... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1161 | Q6 | What genes does Bortezomib target when it's used to treat intrahepatic cholangiocarcinoma? | Bortezomib has not been approved by the FDA as a treatment for intrahepatic cholangiocarcinoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are PSMD1, PSMB2, PSMB1, PSMB5, PSMB8, PSMB9, PSMB6, PSMD14, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMA7, PSMA8, PS... | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%bortezomib%" OR LOWER(tradeNames_list) LIKE "%bor... | [{'UUID': 'DrugTargetsIndication121923_text_342340', 'drugName': 'Bortezomib', 'tradeNames_list': "['Velcade']", 'syns_list': "['Bortezomib', 'Bortezomib accord', 'Bortezomib hydrate', 'LDP-341NSC-681239', 'PS-341', 'Velcade']", 'target': 'ENSG00000126067', 'approvedSymbol': 'PSMB2', 'approvedName': 'proteasome 20S sub... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.945 | Q6 | What genes does Torsemide target when it's used to treat hypertension? | When used to treat hypertension, the drug Torsemide targets the gene SLC12A1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%torsemide%" OR LOWER(tradeNames_list) LIKE "%tors... | [{'UUID': 'DrugTargetsIndication121923_text_1149090', 'drugName': 'Torsemide', 'tradeNames_list': "['Demadex', 'Soaanz', 'Torem 10', 'Torem 2.5', 'Torem 5', 'Torsemide']", 'syns_list': "['AC-4464', 'AC4464', 'BM-02.015', 'BM-02015', 'BM02.015', 'LupracTorasemide', 'Torasemide anhydrous', 'Torsemide', 'Upcard']", 'targe... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.290 | Q6 | What genes does Ciclesonide target when it's used to treat Airway obstruction? | When used to treat Airway obstruction, the drug Ciclesonide targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ciclesonide%" OR LOWER(tradeNames_list) LIKE "%ci... | [{'UUID': 'DrugTargetsIndication121923_text_217452', 'drugName': 'Ciclesonide', 'tradeNames_list': "['Alvesco', 'Alvesco 160', 'Alvesco 80', 'Omnaris', 'Zetonna']", 'syns_list': "['BI54903', 'Ciclesonide', 'RPR-251526', 'RPR251526']", 'target': 'ENSG00000113580', 'approvedSymbol': 'NR3C1', 'approvedName': 'nuclear rece... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1947 | Q6 | What genes does Paclitaxel target when it's used to treat rectum cancer? | Paclitaxel has not been approved by the FDA as a treatment for rectum cancer, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are TUBB4B, TUBB1, TUBA3C, TUBA4A, TUBB3, TUBA1A, TUBB4A, TUBB8, TUBB, TUBA1B, TUBA1C, TUBA3E, TUBB2A, TUBB2B, and TUBB6. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%paclitaxel%" OR LOWER(tradeNames_list) LIKE "%pac... | [{'UUID': 'DrugTargetsIndication121923_text_796', 'drugName': 'Paclitaxel', 'tradeNames_list': "['Abraxane', 'Pacitaxel', 'Paclitaxel', 'Paxene', 'Taxol', 'Taxol 100']", 'syns_list': "['(-)-paclitaxel', 'ABI-007', 'ABI-007 COMPONENT PACLITAXEL', 'BMS 181339-01BMS-181339-01', 'Capxol', 'Cyclopax', 'DHP 107', 'DHP-107', ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.973 | Q6 | What genes does Alpelisib target when it's used to treat cancer? | When used to treat cancer, the drug Alpelisib targets the gene PIK3CA. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%alpelisib%" OR LOWER(tradeNames_list) LIKE "%alpe... | [{'UUID': 'DrugTargetsIndication121923_text_939757', 'drugName': 'Alpelisib', 'tradeNames_list': "['Piqray', 'Vijoice']", 'syns_list': "['Alpelisib', 'BYL-719', 'BYL719', 'Byl-719', 'NVP-BYL719', 'Vijoice']", 'target': 'ENSG00000121879', 'approvedSymbol': 'PIK3CA', 'approvedName': 'phosphatidylinositol-4,5-bisphosphate... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.605 | Q6 | What genes does Crizotinib target when it's used to treat non-small cell lung carcinoma? | When used to treat non-small cell lung carcinoma, the drug Crizotinib targets the genes MET, ALK, EML4, and NPM1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%crizotinib%" OR LOWER(tradeNames_list) LIKE "%cri... | [{'UUID': 'DrugTargetsIndication121923_text_934400', 'drugName': 'Crizotinib', 'tradeNames_list': "['Xalkori']", 'syns_list': "['Crizotinib', 'NSC-756645', 'PF-02341066', 'PF-2341066', 'Pf-2341066']", 'target': 'ENSG00000105976', 'approvedSymbol': 'MET', 'approvedName': 'MET proto-oncogene, receptor tyrosine kinase', '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1312 | Q6 | What genes does Gemcitabine Hydrochloride target when it's used to treat renal cell carcinoma? | Gemcitabine Hydrochloride has not been approved by the FDA as a treatment for renal cell carcinoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are POLA1, POLD4, POLD3, POLD1, POLD2, POLE, POLA2, PRIM1, PRIM2, POLE2, POLE3, RRM1, RRM2B, and RRM2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%gemcitabine hydrochloride%" OR LOWER(tradeNames_l... | [{'UUID': 'DrugTargetsIndication121923_text_756021', 'drugName': 'Gemcitabine Hydrochloride', 'tradeNames_list': "['Gemcitabine hydrochloride', 'Gemzar', 'Infugem']", 'syns_list': "['Gemcitabine (as hydrochloride)', 'Gemcitabine hclGemcitabine hydrochloride', 'Gemzar', 'LY-188011LY-188011 HYDROCHLORIDE', 'LY188011 HYDR... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1244 | Q6 | What genes does Dexamethasone target when it's used to treat pemphigus? | When used to treat pemphigus, the drug Dexamethasone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dexamethasone%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_226932', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1638 | Q6 | What genes does Pomalidomide target when it's used to treat multiple myeloma? | When used to treat multiple myeloma, the drug Pomalidomide targets the genes CRBN, DDB1, CUL4A, and RBX1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%pomalidomide%" OR LOWER(tradeNames_list) LIKE "%p... | [{'UUID': 'DrugTargetsIndication121923_text_1143578', 'drugName': 'Pomalidomide', 'tradeNames_list': "['Imnovid', 'Pomalyst']", 'syns_list': "['Actimid', 'CC-4047', 'IMID 3', 'IMID-3', 'Pomalidomide']", 'target': 'ENSG00000167986', 'approvedSymbol': 'DDB1', 'approvedName': 'damage specific DNA binding protein 1', 'mesh... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1588 | Q6 | What genes does Doxepin Hydrochloride target when it's used to treat atopic eczema? | When used to treat atopic eczema, the drug Doxepin Hydrochloride targets the gene SLC6A2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%doxepin hydrochloride%" OR LOWER(tradeNames_list)... | [{'UUID': 'DrugTargetsIndication121923_text_440813', 'drugName': 'Doxepin Hydrochloride', 'tradeNames_list': "['Adapin', 'Doxepin hydrochloride', 'Quitaxon', 'Silenor', 'Sinequan', 'XepinZonalon']", 'syns_list': "['Doxepin hcl', 'Doxepin hydrochloride', 'NSC-108160', 'P-3693A']", 'target': 'ENSG00000103546', 'approvedS... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1316 | Q6 | What genes does Loteprednol Etabonate target when it's used to treat allergic conjunctivitis? | When used to treat allergic conjunctivitis, the drug Loteprednol Etabonate targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%loteprednol etabonate%" OR LOWER(tradeNames_list)... | [{'UUID': 'DrugTargetsIndication121923_text_225455', 'drugName': 'Loteprednol Etabonate', 'tradeNames_list': "['Airex', 'Alrex', 'Eysuvis', 'Inveltys', 'Lotemax', 'Lotemax sm']", 'syns_list': "['CDDD 5604', 'CDDD-5604', 'HGP-1', 'KPI-121', 'LoteprednolLoteprednol etabonate', 'P-5604']", 'target': 'ENSG00000113580', 'ap... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1779 | Q6 | What genes does Thalidomide target when it's used to treat extranodal nasal NK/T cell lymphoma? | Thalidomide has not been approved by the FDA as a treatment for extranodal nasal NK/T cell lymphoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are CRBN, DDB1, CUL4A, and RBX1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%thalidomide%" OR LOWER(tradeNames_list) LIKE "%th... | [{'UUID': 'DrugTargetsIndication121923_text_1105128', 'drugName': 'Thalidomide', 'tradeNames_list': "['Talidex', 'Thalomid']", 'syns_list': "['.alpha.-phthalimidoglutarimide', 'Celgene', 'Contergan', 'Distaval', 'K-17Myrin', 'N-phthalylglutamic acid imide', 'NSC-527179', 'NSC-66847Neurosedyn', 'Pantosediv', 'Pharmion',... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1647 | Q6 | What genes does Ondansetron target when it's used to treat Nausea? | When used to treat Nausea, the drug Ondansetron targets the gene HTR3A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ondansetron%" OR LOWER(tradeNames_list) LIKE "%on... | [{'UUID': 'DrugTargetsIndication121923_text_205863', 'drugName': 'Ondansetron', 'tradeNames_list': "['Ondansetron', 'Zofran', 'Zofran odt', 'Zuplenz']", 'syns_list': "['A04AA01', 'Desmethylondansetron', 'EUR-1025', 'GR-38032', 'GR-38032FNSC-757870', 'Ondansetron', 'Zofran']", 'target': 'ENSG00000166736', 'approvedSymbo... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1255 | Q6 | What genes does Larotrectinib Sulfate target when it's used to treat neoplasm? | When used to treat neoplasm, the drug Larotrectinib Sulfate targets the genes NTRK1, NTRK2, and NTRK3. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%larotrectinib sulfate%" OR LOWER(tradeNames_list)... | [{'UUID': 'DrugTargetsIndication121923_text_942606', 'drugName': 'Larotrectinib Sulfate', 'tradeNames_list': "['Vitrakvi']", 'syns_list': "['ARRY-470 SULFATE', 'LOXO-101 sulfate', 'Larotrectinib sulfate']", 'target': 'ENSG00000198400', 'approvedSymbol': 'NTRK1', 'approvedName': 'neurotrophic receptor tyrosine kinase 1'... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1675 | Q6 | What genes does Dasatinib target when it's used to treat mycosis fungoides? | Dasatinib has not been approved by the FDA as a treatment for mycosis fungoides, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are ABL1, BCR, HCK, SRC, LYN, KIT, PDGFRB, EPHA2, FRK, FYN, LCK, YES1, BLK, FGR, and SRMS. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dasatinib%" OR LOWER(tradeNames_list) LIKE "%dasa... | [{'UUID': 'DrugTargetsIndication121923_text_713541', 'drugName': 'Dasatinib', 'tradeNames_list': "['Dasatinib', 'Sprycel']", 'syns_list': "['BMS-354825', 'BMS-354825 HYDRATE', 'BMS-354825-03', 'DasatinibDasatinib anhydrous', 'Dasatinib hydrate', 'Dasatinib monohydrateNSC-759877']", 'target': 'ENSG00000097007', 'approve... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1801 | Q6 | What genes does Sumatriptan Succinate target when it's used to treat migraine with aura? | Sumatriptan Succinate has not been approved by the FDA as a treatment for migraine with aura, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are HTR1B and HTR1D. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%sumatriptan succinate%" OR LOWER(tradeNames_list)... | [{'UUID': 'DrugTargetsIndication121923_text_937282', 'drugName': 'Sumatriptan Succinate', 'tradeNames_list': "['Alsuma', 'Imigran', 'Imigran 50', 'Imigran radis', 'Imigran recoveryImigran subject', 'Imitrex', 'Imitrex statdose', 'MigraitanMigraleve ultra', 'Onzetra xsail', 'Sumatriptan succinateSumavel dosepro', 'Zecui... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.759 | Q6 | What genes does Vortioxetine Hydrobromide target when it's used to treat major depressive disorder? | When used to treat major depressive disorder, the drug Vortioxetine Hydrobromide targets the genes HTR3A, SLC6A4, and HTR1A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%vortioxetine hydrobromide%" OR LOWER(tradeNames_l... | [{'UUID': 'DrugTargetsIndication121923_text_205260', 'drugName': 'Vortioxetine Hydrobromide', 'tradeNames_list': "['Trintellix']", 'syns_list': "['Lu AA21004 (HBr)', 'Lu aa21004 hbr', 'Lu-aa21004 hydrobromideVortioxetine hydrobromide']", 'target': 'ENSG00000166736', 'approvedSymbol': 'HTR3A', 'approvedName': '5-hydroxy... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.616 | Q6 | What genes does Cabazitaxel target when it's used to treat head and neck squamous cell carcinoma? | Cabazitaxel has not been approved by the FDA as a treatment for head and neck squamous cell carcinoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are TUBB4B, TUBB1, TUBA3C, TUBA4A, TUBB3, TUBA1A, TUBB4A, TUBB8, TUBB, TUBA1B, TUBA1C, TUBA3E, TUBB2A, TUBB2B, a... | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%cabazitaxel%" OR LOWER(tradeNames_list) LIKE "%ca... | [{'UUID': 'DrugTargetsIndication121923_text_67983', 'drugName': 'Cabazitaxel', 'tradeNames_list': "['Jevtana', 'Jevtana kit']", 'syns_list': "['Cabazitaxel', 'Cabazitaxel acetonate', 'Jevtana', 'NSC-761432', 'TXD 258TXD-258', 'XRP 6258', 'XRP-6258']", 'target': 'ENSG00000188229', 'approvedSymbol': 'TUBB4B', 'approvedNa... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1045 | Q6 | What genes does Nizatidine target when it's used to treat gastroesophageal reflux disease? | When used to treat gastroesophageal reflux disease, the drug Nizatidine targets the gene HRH2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%nizatidine%" OR LOWER(tradeNames_list) LIKE "%niz... | [{'UUID': 'DrugTargetsIndication121923_text_1100310', 'drugName': 'Nizatidine', 'tradeNames_list': "['Axid', 'Axid ar', 'Nizatidine', 'Zinga 150', 'Zinga 300']", 'syns_list': "['Acinon', 'LY 139037', 'LY-139037', 'NSC-759289', 'Nizatidine']", 'target': 'ENSG00000113749', 'approvedSymbol': 'HRH2', 'approvedName': 'hista... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.788 | Q6 | What genes does Docetaxel target when it's used to treat breast cancer? | When used to treat breast cancer, the drug Docetaxel targets the genes TUBB4B, TUBB1, TUBA3C, TUBA4A, TUBB3, TUBA1A, TUBB4A, TUBB8, TUBB, TUBA1B, TUBA1C, TUBA3E, TUBB2A, TUBB2B, and TUBB6. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%docetaxel%" OR LOWER(tradeNames_list) LIKE "%doce... | [{'UUID': 'DrugTargetsIndication121923_text_104604', 'drugName': 'Docetaxel', 'tradeNames_list': "['Docefrez', 'Docetaxel', 'Taxceus', 'Taxotere']", 'syns_list': "['Bind 014', 'CKD-810', 'Docetaxel', 'Docetaxel (as trihydrate)Docetaxel anhydrous', 'Docetaxel hydrate', 'Docetaxel trihydrateNSC-628503', 'RP 56976', 'RP-5... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1690 | Q6 | What genes does Crizotinib target when it's used to treat papillary renal cell carcinoma? | Crizotinib has not been approved by the FDA as a treatment for papillary renal cell carcinoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are MET, ALK, EML4, and NPM1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%crizotinib%" OR LOWER(tradeNames_list) LIKE "%cri... | [{'UUID': 'DrugTargetsIndication121923_text_934388', 'drugName': 'Crizotinib', 'tradeNames_list': "['Xalkori']", 'syns_list': "['Crizotinib', 'NSC-756645', 'PF-02341066', 'PF-2341066', 'Pf-2341066']", 'target': 'ENSG00000105976', 'approvedSymbol': 'MET', 'approvedName': 'MET proto-oncogene, receptor tyrosine kinase', '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.997 | Q6 | What genes does Dabigatran target when it's used to treat hemorrhage? | Dabigatran has not been approved by the FDA as a treatment for hemorrhage, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is F2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dabigatran%" OR LOWER(tradeNames_list) LIKE "%dab... | [{'UUID': 'DrugTargetsIndication121923_text_1093462', 'drugName': 'Dabigatran', 'tradeNames_list': "['Pradaxa']", 'syns_list': "['BIBR 953 ZW', 'BIBR-953', 'BIBR-953-ZW', 'DabigatranPradaxa (dabigatran)']", 'target': 'ENSG00000180210', 'approvedSymbol': 'F2', 'approvedName': 'coagulation factor II, thrombin', 'mesh_hea... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.499 | Q6 | What genes does Bupivacaine target when it's used to treat Hallux valgus? | Bupivacaine has not been approved by the FDA as a treatment for Hallux valgus, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is SCN4A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%bupivacaine%" OR LOWER(tradeNames_list) LIKE "%bu... | [{'UUID': 'DrugTargetsIndication121923_text_663104', 'drugName': 'Bupivacaine', 'tradeNames_list': "['Anekain', 'Exparel', 'Marcaine', 'Posimir', 'Sensorcaine']", 'syns_list': "['Bucaine', 'Bupivacaine', 'Bupivacaine liposome', 'LIQ-865', 'LIQ865Liposomal bupivacaine', 'MarcaineRopivacaine hydrochloride impurity, bupiv... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1320 | Q6 | What genes does Vericiguat target when it's used to treat cardiovascular disease? | When used to treat cardiovascular disease, the drug Vericiguat targets the genes GUCY1B1, GUCY1B2, GUCY1A2, and GUCY1A1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%vericiguat%" OR LOWER(tradeNames_list) LIKE "%ver... | [{'UUID': 'DrugTargetsIndication121923_text_972740', 'drugName': 'Vericiguat', 'tradeNames_list': "['Verquvo']", 'syns_list': "['BAY 1021189', 'BAY-1021189', 'MK-1242', 'Vericiguat']", 'target': 'ENSG00000061918', 'approvedSymbol': 'GUCY1B1', 'approvedName': 'guanylate cyclase 1 soluble subunit beta 1', 'mesh_heading':... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.281 | Q6 | What genes does Guanfacine target when it's used to treat nicotine dependence? | Guanfacine has not been approved by the FDA as a treatment for nicotine dependence, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are ADRA2A, ADRA2C, and ADRA2B. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%guanfacine%" OR LOWER(tradeNames_list) LIKE "%gua... | [{'UUID': 'DrugTargetsIndication121923_text_1025427', 'drugName': 'Guanfacine', 'tradeNames_list': "['Intuniv']", 'syns_list': "['Guanfacine', 'NSC-759121', 'Tenex']", 'target': 'ENSG00000150594', 'approvedSymbol': 'ADRA2A', 'approvedName': 'adrenoceptor alpha 2A', 'mesh_heading': 'Tobacco Use Disorder', 'efo_term': 'n... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1848 | Q6 | What genes does Fexofenadine Hydrochloride target when it's used to treat urticaria? | When used to treat urticaria, the drug Fexofenadine Hydrochloride targets the gene HRH1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fexofenadine hydrochloride%" OR LOWER(tradeNames_... | [{'UUID': 'DrugTargetsIndication121923_text_455784', 'drugName': 'Fexofenadine Hydrochloride', 'tradeNames_list': '[\'Allegra\', \'Allegra allergy\', \'Allegra hives\', "Children\'s allegra allergyChildren\'s allegra hivesChildren\'s fexofenadine hydrochloride allergyChildren\'s fexofenadine hydrochloride hivesFexofena... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.363 | Q6 | What genes does Exenatide target when it's used to treat type 2 diabetes mellitus? | When used to treat type 2 diabetes mellitus, the drug Exenatide targets the gene GLP1R. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%exenatide%" OR LOWER(tradeNames_list) LIKE "%exen... | [{'UUID': 'DrugTargetsIndication121923_text_1045995', 'drugName': 'Exenatide', 'tradeNames_list': "['Bydureon', 'Bydureon bcise', 'Bydureon pen', 'Byetta']", 'syns_list': "['AC 2993', 'AC-002993', 'AC-2993', 'AC-2993A', 'AC-2993LAR', 'AC002993AC2993', 'AC2993A', 'DA-3091', 'EXENDIN-4', 'ExenatideExenatide Synthetic', '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1179 | Q6 | What genes does Lamotrigine target when it's used to treat bipolar I disorder? | When used to treat bipolar I disorder, the drug Lamotrigine targets the genes SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lamotrigine%" OR LOWER(tradeNames_list) LIKE "%la... | [{'UUID': 'DrugTargetsIndication121923_text_653155', 'drugName': 'Lamotrigine', 'tradeNames_list': "['Lamictal', 'Lamictal cd', 'Lamictal odt', 'Lamictal xr', 'Lamotrigine']", 'syns_list': "['BW 430C', 'BW-430C', 'Lamotrigine', 'NSC-759171']", 'target': 'ENSG00000144285', 'approvedSymbol': 'SCN1A', 'approvedName': 'sod... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.239 | Q6 | What genes does Everolimus target when it's used to treat immune system disease? | When used to treat immune system disease, the drug Everolimus targets the gene FKBP1A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%everolimus%" OR LOWER(tradeNames_list) LIKE "%eve... | [{'UUID': 'DrugTargetsIndication121923_text_1085632', 'drugName': 'Everolimus', 'tradeNames_list': "['Afinitor', 'Afinitor disperz', 'Certican', 'Votubia', 'Zortress']", 'syns_list': "['40-o-(2-hydroxyethyl)-rapamycin', 'Everolimus', 'RAD 666', 'RAD-001RAD-666', 'RAD001', 'SDZ-RAD', 'Sdz rad']", 'target': 'ENSG00000088... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.557 | Q6 | What genes does Isotretinoin target when it's used to treat breast cancer? | Isotretinoin has not been approved by the FDA as a treatment for breast cancer, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are RARG, RARB, and RARA. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%isotretinoin%" OR LOWER(tradeNames_list) LIKE "%i... | [{'UUID': 'DrugTargetsIndication121923_text_1054012', 'drugName': 'Isotretinoin', 'tradeNames_list': "['Absorica', 'Absorica ld', 'Accutane', 'Amnesteem', 'Claravis', 'IsotrexMyorisan', 'Roaccutane', 'Sotret', 'Zenatane']", 'syns_list': "['13 Cis-Retinoic Acid', '13-cis-retinoic acid', 'Isotretinoin', 'NSC-758156PAT-00... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1870 | Q6 | What genes does Guanfacine target when it's used to treat hypertension? | When used to treat hypertension, the drug Guanfacine targets the genes ADRA2A, ADRA2C, and ADRA2B. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%guanfacine%" OR LOWER(tradeNames_list) LIKE "%gua... | [{'UUID': 'DrugTargetsIndication121923_text_1025306', 'drugName': 'Guanfacine Hydrochloride', 'tradeNames_list': "['Akfen', 'Estulic', 'Guanfacine hydrochloride', 'Intuniv', 'Tenex']", 'syns_list': "['BS 100-141', 'BS-100-141', 'Guafacine hydrochloride', 'Guanfacine hclGuanfacine hydrochloride', 'SPD503']", 'target': '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1915 | Q6 | What genes does Methotrexate target when it's used to treat follicular lymphoma? | Methotrexate has not been approved by the FDA as a treatment for follicular lymphoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is DHFR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%methotrexate%" OR LOWER(tradeNames_list) LIKE "%m... | [{'UUID': 'DrugTargetsIndication121923_text_1057575', 'drugName': 'Methotrexate', 'tradeNames_list': "['Amethopterin', 'Ebetrex', 'Emtexate high-pot', 'Emtexate pf', 'FolexMaxtrex', 'Methotrexate', 'Metoject', 'Mexate', 'Otrexup', 'Otrexup pfsRasuvo', 'Reditrex', 'Rheumatrex', 'Trexall', 'Zlatal']", 'syns_list': "['(r)... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.211 | Q6 | What genes does Roflumilast target when it's used to treat rosacea? | Roflumilast has not been approved by the FDA as a treatment for rosacea, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are PDE4A, PDE4D, PDE4B, and PDE4C. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%roflumilast%" OR LOWER(tradeNames_list) LIKE "%ro... | [{'UUID': 'DrugTargetsIndication121923_text_695481', 'drugName': 'Roflumilast', 'tradeNames_list': "['Daliresp', 'Daxas', 'Zoryve']", 'syns_list': "['Arq-151', 'B-9302-107', 'B9302-107', 'BY-217', 'BY217', 'BYK-20869BYK20869', 'Roflumilast', 'Zoryve']", 'target': 'ENSG00000065989', 'approvedSymbol': 'PDE4A', 'approvedN... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1922 | Q6 | What genes does Venetoclax target when it's used to treat chronic lymphocytic leukemia? | When used to treat chronic lymphocytic leukemia, the drug Venetoclax targets the gene BCL2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%venetoclax%" OR LOWER(tradeNames_list) LIKE "%ven... | [{'UUID': 'DrugTargetsIndication121923_text_989881', 'drugName': 'Venetoclax', 'tradeNames_list': "['Venclexta']", 'syns_list': "['ABT-199', 'GDC-0199', 'RG-7601', 'RG7601', 'Venetoclax']", 'target': 'ENSG00000171791', 'approvedSymbol': 'BCL2', 'approvedName': 'BCL2 apoptosis regulator', 'mesh_heading': 'Leukemia, Lymp... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1561 | Q6 | What genes does Roflumilast target when it's used to treat Airway obstruction? | When used to treat Airway obstruction, the drug Roflumilast targets the genes PDE4A, PDE4D, PDE4B, and PDE4C. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%roflumilast%" OR LOWER(tradeNames_list) LIKE "%ro... | [{'UUID': 'DrugTargetsIndication121923_text_695489', 'drugName': 'Roflumilast', 'tradeNames_list': "['Daliresp', 'Daxas', 'Zoryve']", 'syns_list': "['Arq-151', 'B-9302-107', 'B9302-107', 'BY-217', 'BY217', 'BYK-20869BYK20869', 'Roflumilast', 'Zoryve']", 'target': 'ENSG00000065989', 'approvedSymbol': 'PDE4A', 'approvedN... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.60 | Q6 | What genes does Duloxetine Hydrochloride target when it's used to treat neuropathic pain? | When used to treat neuropathic pain, the drug Duloxetine Hydrochloride targets the genes SLC6A4 and SLC6A2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%duloxetine hydrochloride%" OR LOWER(tradeNames_li... | [{'UUID': 'DrugTargetsIndication121923_text_206078', 'drugName': 'Duloxetine Hydrochloride', 'tradeNames_list': "['Ariclaim', 'Cymbalta', 'Drizalma sprinkle', 'DuciltiaDuloxetine hydrochloride', 'Yentreve']", 'syns_list': "['Ariclaim', 'Duloxetine (as hydrochloride)', 'Duloxetine hclDuloxetine hydrochloride', 'Duloxeti... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1835 | Q6 | What genes does Vorinostat target when it's used to treat neoplasm? | When used to treat neoplasm, the drug Vorinostat targets the genes HDAC1, HDAC3, HDAC6, and HDAC2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%vorinostat%" OR LOWER(tradeNames_list) LIKE "%vor... | [{'UUID': 'DrugTargetsIndication121923_text_1077226', 'drugName': 'Vorinostat', 'tradeNames_list': "['Zolinza']", 'syns_list': "['MK-0683', 'MK0683', 'NSC-701852', 'NSC-748799', 'NSC-759852Suberoylanilide hydroxamic acid', 'Vorinostat']", 'target': 'ENSG00000116478', 'approvedSymbol': 'HDAC1', 'approvedName': 'histone ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1906 | Q6 | What genes does Bosutinib target when it's used to treat Thymoma? | Bosutinib has not been approved by the FDA as a treatment for Thymoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are ABL1, BCR, HCK, SRC, and LYN. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%bosutinib%" OR LOWER(tradeNames_list) LIKE "%bosu... | [{'UUID': 'DrugTargetsIndication121923_text_710980', 'drugName': 'Bosutinib', 'tradeNames_list': "['Bosulif']", 'syns_list': "['Bosutinib', 'Bosutinib (as monohydrate)', 'Bosutinib hydrateBosutinib monohydrate', 'SK-606', 'SKI-606']", 'target': 'ENSG00000097007', 'approvedSymbol': 'ABL1', 'approvedName': 'ABL proto-onc... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1578 | Q6 | What genes does Axitinib target when it's used to treat head and neck squamous cell carcinoma? | Axitinib has not been approved by the FDA as a treatment for head and neck squamous cell carcinoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are KDR, FLT1, and FLT4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%axitinib%" OR LOWER(tradeNames_list) LIKE "%axiti... | [{'UUID': 'DrugTargetsIndication121923_text_689335', 'drugName': 'Axitinib', 'tradeNames_list': "['Inlyta']", 'syns_list': "['AG-013736', 'AG-13736', 'Axitinib', 'NSC-757441']", 'target': 'ENSG00000128052', 'approvedSymbol': 'KDR', 'approvedName': 'kinase insert domain receptor', 'mesh_heading': 'Carcinoma, Squamous Ce... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.368 | Q6 | What genes does Docetaxel target when it's used to treat non-small cell lung carcinoma? | When used to treat non-small cell lung carcinoma, the drug Docetaxel targets the genes TUBB4B, TUBB1, TUBA3C, TUBA4A, TUBB3, TUBA1A, TUBB4A, TUBB8, TUBB, TUBA1B, TUBA1C, TUBA3E, TUBB2A, TUBB2B, and TUBB6. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%docetaxel%" OR LOWER(tradeNames_list) LIKE "%doce... | [{'UUID': 'DrugTargetsIndication121923_text_96052', 'drugName': 'Docetaxel', 'tradeNames_list': "['Docefrez', 'Docetaxel', 'Taxceus', 'Taxotere']", 'syns_list': "['Bind 014', 'CKD-810', 'Docetaxel', 'Docetaxel (as trihydrate)Docetaxel anhydrous', 'Docetaxel hydrate', 'Docetaxel trihydrateNSC-628503', 'RP 56976', 'RP-56... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.511 | Q6 | What genes does Montelukast Sodium target when it's used to treat asthma? | When used to treat asthma, the drug Montelukast Sodium targets the gene CYSLTR1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%montelukast sodium%" OR LOWER(tradeNames_list) LI... | [{'UUID': 'DrugTargetsIndication121923_text_1100396', 'drugName': 'Montelukast Sodium', 'tradeNames_list': "['Montelukast sodium', 'Singulair']", 'syns_list': "['MK-476', 'Montelukast (as sodium)', 'Montelukast monosodium saltMontelukast sodium', 'NSC-759107']", 'target': 'ENSG00000173198', 'approvedSymbol': 'CYSLTR1',... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.815 | Q6 | What genes does Meloxicam target when it's used to treat migraine disorder? | Meloxicam has not been approved by the FDA as a treatment for migraine disorder, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is PTGS2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%meloxicam%" OR LOWER(tradeNames_list) LIKE "%melo... | [{'UUID': 'DrugTargetsIndication121923_text_842371', 'drugName': 'Meloxicam', 'tradeNames_list': "['Anjeso', 'Meloxicam', 'Mobic', 'Qmiiz odt', 'Vivlodex']", 'syns_list': "['Acticam', 'Contacera', 'Coxicam', 'Emdocam', 'Flexicam', 'Inflacam', 'LoxicomMelfax', 'Melosus', 'Melovem', 'Meloxicam', 'Meloxidolor', 'Meloxidyl... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1122 | Q6 | What genes does Balsalazide Disodium target when it's used to treat ulcerative colitis? | When used to treat ulcerative colitis, the drug Balsalazide Disodium targets the genes PTGS2, PTGS1, PPARG, and ALOX5. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%balsalazide disodium%" OR LOWER(tradeNames_list) ... | [{'UUID': 'DrugTargetsIndication121923_text_828148', 'drugName': 'Balsalazide Disodium', 'tradeNames_list': "['Balsalazide disodium', 'Colazal', 'Colazide', 'Giazo']", 'syns_list': "['BX-661A', 'BX661A', 'Balsalazide disodiumBalsalazide disodium anhydrous', 'Balsalazide disodium dihydrateBalsalazide disodium salt dihyd... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1731 | Q6 | What genes does Amisulpride target when it's used to treat schizophrenia? | Amisulpride has not been approved by the FDA as a treatment for schizophrenia, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are HTR2C, DRD2, DRD3, HTR2A, HTR3A, HTR1A, HTR3E, HTR3B, HTR3D, HTR3C, HTR4, HTR1F, HTR2B, HTR1B, HTR1D, HTR1E, HTR7, HTR6, and HTR5A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%amisulpride%" OR LOWER(tradeNames_list) LIKE "%am... | [{'UUID': 'DrugTargetsIndication121923_text_151510', 'drugName': 'Amisulpride', 'tradeNames_list': "['Barhemsys', 'Solian', 'Solian 100', 'Solian 200', 'Solian 400', 'Solian 50']", 'syns_list': "['APD-421', 'APD421', 'Aminosultopride', 'Amisulpride', 'DAN-2163', 'DenibanNSC-760085', 'Socian', 'Sulamid']", 'target': 'EN... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1216 | Q6 | What genes does Dabigatran Etexilate Mesylate target when it's used to treat stroke? | When used to treat stroke, the drug Dabigatran Etexilate Mesylate targets the gene F2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dabigatran etexilate mesylate%" OR LOWER(tradeNam... | [{'UUID': 'DrugTargetsIndication121923_text_1092394', 'drugName': 'Dabigatran Etexilate Mesylate', 'tradeNames_list': "['Pradaxa']", 'syns_list': "['BIBR 1048 MS', 'BIBR-1048-MS', 'Dabigatran etexilate mesilateDabigatran etexilate mesylate']", 'target': 'ENSG00000180210', 'approvedSymbol': 'F2', 'approvedName': 'coagul... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1212 | Q6 | What genes does Diclofenac target when it's used to treat depressive disorder? | Diclofenac has not been approved by the FDA as a treatment for depressive disorder, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%diclofenac%" OR LOWER(tradeNames_list) LIKE "%dic... | [{'UUID': 'DrugTargetsIndication121923_text_837110', 'drugName': 'Diclofenac', 'tradeNames_list': "['Cambia', 'Voltaren', 'Voltaren Ophthalmic', 'Voltaren Xr', 'ZorvolexZorvolex capsules']", 'syns_list': "['Arthrotec', 'Cataflam', 'Diclofenac', 'Diclofenac acidDiclofenac free acid', 'LAS-41007', 'LAS41007', 'Las41007',... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.971 | Q6 | What genes does Bempedoic Acid target when it's used to treat coronary artery disease? | When used to treat coronary artery disease, the drug Bempedoic Acid targets the gene ACLY. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%bempedoic acid%" OR LOWER(tradeNames_list) LIKE "... | [{'UUID': 'DrugTargetsIndication121923_text_1191841', 'drugName': 'Bempedoic Acid', 'tradeNames_list': "['Nexletol']", 'syns_list': "['Bempedoic acid', 'ESP-55016', 'ETC-1002', 'ETC1002']", 'target': 'ENSG00000131473', 'approvedSymbol': 'ACLY', 'approvedName': 'ATP citrate lyase', 'mesh_heading': 'Coronary Artery Disea... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.805 | Q6 | What genes does Perampanel target when it's used to treat epilepsy with generalized tonic-clonic seizures? | Perampanel has not been approved by the FDA as a treatment for epilepsy with generalized tonic-clonic seizures, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are GRIA4, GRIA3, GRIA2, and GRIA1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%perampanel%" OR LOWER(tradeNames_list) LIKE "%per... | [{'UUID': 'DrugTargetsIndication121923_text_969693', 'drugName': 'Perampanel', 'tradeNames_list': "['Fycompa']", 'syns_list': "['E-2007', 'E2007', 'ER-155055-90', 'Perampanel']", 'target': 'ENSG00000152578', 'approvedSymbol': 'GRIA4', 'approvedName': 'glutamate ionotropic receptor AMPA type subunit 4', 'mesh_heading': ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.121 | Q6 | What genes does Perampanel target when it's used to treat post-traumatic stress disorder? | Perampanel has not been approved by the FDA as a treatment for post-traumatic stress disorder, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are GRIA4, GRIA3, GRIA2, and GRIA1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%perampanel%" OR LOWER(tradeNames_list) LIKE "%per... | [{'UUID': 'DrugTargetsIndication121923_text_969683', 'drugName': 'Perampanel', 'tradeNames_list': "['Fycompa']", 'syns_list': "['E-2007', 'E2007', 'ER-155055-90', 'Perampanel']", 'target': 'ENSG00000152578', 'approvedSymbol': 'GRIA4', 'approvedName': 'glutamate ionotropic receptor AMPA type subunit 4', 'mesh_heading': ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1322 | Q6 | What genes does Relugolix target when it's used to treat prostate cancer? | When used to treat prostate cancer, the drug Relugolix targets the gene GNRHR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%relugolix%" OR LOWER(tradeNames_list) LIKE "%relu... | [{'UUID': 'DrugTargetsIndication121923_text_1096979', 'drugName': 'Relugolix', 'tradeNames_list': "['Orgovyx']", 'syns_list': "['Relugolix', 'TAK-385', 'Tak-385']", 'target': 'ENSG00000109163', 'approvedSymbol': 'GNRHR', 'approvedName': 'gonadotropin releasing hormone receptor', 'mesh_heading': 'Prostatic Neoplasms', '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1221 | Q6 | What genes does Sumatriptan target when it's used to treat migraine disorder? | When used to treat migraine disorder, the drug Sumatriptan targets the genes HTR1B and HTR1D. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%sumatriptan%" OR LOWER(tradeNames_list) LIKE "%su... | [{'UUID': 'DrugTargetsIndication121923_text_937225', 'drugName': 'Sumatriptan', 'tradeNames_list': "['Imitrex', 'Sumatriptan', 'Tosymra']", 'syns_list': "['Dfn-11', 'Dfn-11 (sumatriptan injection)', 'N02CC01', 'Sumatriptan']", 'target': 'ENSG00000135312', 'approvedSymbol': 'HTR1B', 'approvedName': '5-hydroxytryptamine ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.528 | Q6 | What genes does Montelukast Sodium target when it's used to treat Rhinitis, Allergic, Perennial? | When used to treat Rhinitis, Allergic, Perennial, the drug Montelukast Sodium targets the gene CYSLTR1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%montelukast sodium%" OR LOWER(tradeNames_list) LI... | [{'UUID': 'DrugTargetsIndication121923_text_1100395', 'drugName': 'Montelukast Sodium', 'tradeNames_list': "['Montelukast sodium', 'Singulair']", 'syns_list': "['MK-476', 'Montelukast (as sodium)', 'Montelukast monosodium saltMontelukast sodium', 'NSC-759107']", 'target': 'ENSG00000173198', 'approvedSymbol': 'CYSLTR1',... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.519 | Q6 | What genes does Paclitaxel target when it's used to treat cholangiocarcinoma? | Paclitaxel has not been approved by the FDA as a treatment for cholangiocarcinoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are TUBB4B, TUBB1, TUBA3C, TUBA4A, TUBB3, TUBA1A, TUBB4A, TUBB8, TUBB, TUBA1B, TUBA1C, TUBA3E, TUBB2A, TUBB2B, and TUBB6. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%paclitaxel%" OR LOWER(tradeNames_list) LIKE "%pac... | [{'UUID': 'DrugTargetsIndication121923_text_369', 'drugName': 'Paclitaxel', 'tradeNames_list': "['Abraxane', 'Pacitaxel', 'Paclitaxel', 'Paxene', 'Taxol', 'Taxol 100']", 'syns_list': "['(-)-paclitaxel', 'ABI-007', 'ABI-007 COMPONENT PACLITAXEL', 'BMS 181339-01BMS-181339-01', 'Capxol', 'Cyclopax', 'DHP 107', 'DHP-107', ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.84 | Q6 | What genes does Telmisartan target when it's used to treat albuminuria? | Telmisartan has not been approved by the FDA as a treatment for albuminuria, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is AGTR1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%telmisartan%" OR LOWER(tradeNames_list) LIKE "%te... | [{'UUID': 'DrugTargetsIndication121923_text_1072702', 'drugName': 'Telmisartan', 'tradeNames_list': "['Micardis', 'Telmisartan', 'Tolura']", 'syns_list': "['BIBR 277 SE', 'BIBR-277', 'BIBR-277 SE', 'BIBR-277-SE', 'BIBR-277SEC09CA07', 'Kinzalmono', 'Pritor', 'Semintra', 'TelmisartanTelmisartan actavis', 'Telmisartan tev... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.717 | Q6 | What genes does Levodopa target when it's used to treat brain injury? | Levodopa has not been approved by the FDA as a treatment for brain injury, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is DRD3. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%levodopa%" OR LOWER(tradeNames_list) LIKE "%levod... | [{'UUID': 'DrugTargetsIndication121923_text_204988', 'drugName': 'Levodopa', 'tradeNames_list': "['Bendopa', 'Brocadopa', 'Dopar', 'Inbrija', 'Larodopa']", 'syns_list': "['Bendopa', 'Cvt-301', 'Levodopa', 'Levodopum', 'NSC-118381', 'V-1512']", 'target': 'ENSG00000151577', 'approvedSymbol': 'DRD3', 'approvedName': 'dopa... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1185 | Q6 | What genes does Dexamethasone target when it's used to treat Thrombocytopenia? | When used to treat Thrombocytopenia, the drug Dexamethasone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dexamethasone%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_227739', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.386 | Q6 | What genes does Plecanatide target when it's used to treat Constipation? | When used to treat Constipation, the drug Plecanatide targets the gene GUCY2C. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%plecanatide%" OR LOWER(tradeNames_list) LIKE "%pl... | [{'UUID': 'DrugTargetsIndication121923_text_1092237', 'drugName': 'Plecanatide', 'tradeNames_list': "['Trulance']", 'syns_list': "['Guanilib', 'Plecanatide', 'SP-304', 'SP-304 (SYNERGY)']", 'target': 'ENSG00000070019', 'approvedSymbol': 'GUCY2C', 'approvedName': 'guanylate cyclase 2C', 'mesh_heading': 'Constipation', '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1022 | Q6 | What genes does Loteprednol Etabonate target when it's used to treat inflammation? | When used to treat inflammation, the drug Loteprednol Etabonate targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%loteprednol etabonate%" OR LOWER(tradeNames_list)... | [{'UUID': 'DrugTargetsIndication121923_text_225430', 'drugName': 'Loteprednol Etabonate', 'tradeNames_list': "['Airex', 'Alrex', 'Eysuvis', 'Inveltys', 'Lotemax', 'Lotemax sm']", 'syns_list': "['CDDD 5604', 'CDDD-5604', 'HGP-1', 'KPI-121', 'LoteprednolLoteprednol etabonate', 'P-5604']", 'target': 'ENSG00000113580', 'ap... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1689 | Q6 | What genes does Dexamethasone target when it's used to treat atopic eczema? | When used to treat atopic eczema, the drug Dexamethasone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dexamethasone%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_227745', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.87 | Q6 | What genes does Lenalidomide target when it's used to treat neuroblastoma? | Lenalidomide has not been approved by the FDA as a treatment for neuroblastoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are CRBN, DDB1, CUL4A, and RBX1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lenalidomide%" OR LOWER(tradeNames_list) LIKE "%l... | [{'UUID': 'DrugTargetsIndication121923_text_1106095', 'drugName': 'Lenalidomide', 'tradeNames_list': "['Revlimid']", 'syns_list': "['CC-5013', 'CDC-501', 'Lenalidomide', 'NSC-747972', 'SYP-1512']", 'target': 'ENSG00000113851', 'approvedSymbol': 'CRBN', 'approvedName': 'cereblon', 'mesh_heading': 'Neuroblastoma', 'efo_t... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1684 | Q6 | What genes does Docetaxel target when it's used to treat Thyroid Gland Undifferentiated (Anaplastic) Carcinoma? | Docetaxel has not been approved by the FDA as a treatment for Thyroid Gland Undifferentiated (Anaplastic) Carcinoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are TUBB4B, TUBB1, TUBA3C, TUBA4A, TUBB3, TUBA1A, TUBB4A, TUBB8, TUBB, TUBA1B, TUBA1C, TUBA3E, TUB... | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%docetaxel%" OR LOWER(tradeNames_list) LIKE "%doce... | [{'UUID': 'DrugTargetsIndication121923_text_95976', 'drugName': 'Docetaxel', 'tradeNames_list': "['Docefrez', 'Docetaxel', 'Taxceus', 'Taxotere']", 'syns_list': "['Bind 014', 'CKD-810', 'Docetaxel', 'Docetaxel (as trihydrate)Docetaxel anhydrous', 'Docetaxel hydrate', 'Docetaxel trihydrateNSC-628503', 'RP 56976', 'RP-56... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.333 | Q6 | What genes does Everolimus target when it's used to treat thyroid cancer? | Everolimus has not been approved by the FDA as a treatment for thyroid cancer, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is FKBP1A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%everolimus%" OR LOWER(tradeNames_list) LIKE "%eve... | [{'UUID': 'DrugTargetsIndication121923_text_1085586', 'drugName': 'Everolimus', 'tradeNames_list': "['Afinitor', 'Afinitor disperz', 'Certican', 'Votubia', 'Zortress']", 'syns_list': "['40-o-(2-hydroxyethyl)-rapamycin', 'Everolimus', 'RAD 666', 'RAD-001RAD-666', 'RAD001', 'SDZ-RAD', 'Sdz rad']", 'target': 'ENSG00000088... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.7 | Q6 | What genes does Brexpiprazole target when it's used to treat unipolar depression? | When used to treat unipolar depression, the drug Brexpiprazole targets the genes DRD2, HTR2A, and HTR1A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%brexpiprazole%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_155831', 'drugName': 'Brexpiprazole', 'tradeNames_list': "['Rexulti']", 'syns_list': "['Brexpiprazole', 'OPC-34712']", 'target': 'ENSG00000149295', 'approvedSymbol': 'DRD2', 'approvedName': 'dopamine receptor D2', 'mesh_heading': 'Depressive Disorder, Major', 'efo_term': 'uni... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.737 | Q6 | What genes does Vorinostat target when it's used to treat diffuse large B-cell lymphoma? | Vorinostat has not been approved by the FDA as a treatment for diffuse large B-cell lymphoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are HDAC1, HDAC3, HDAC6, and HDAC2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%vorinostat%" OR LOWER(tradeNames_list) LIKE "%vor... | [{'UUID': 'DrugTargetsIndication121923_text_1077060', 'drugName': 'Vorinostat', 'tradeNames_list': "['Zolinza']", 'syns_list': "['MK-0683', 'MK0683', 'NSC-701852', 'NSC-748799', 'NSC-759852Suberoylanilide hydroxamic acid', 'Vorinostat']", 'target': 'ENSG00000116478', 'approvedSymbol': 'HDAC1', 'approvedName': 'histone ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.750 | Q6 | What genes does Fluticasone Furoate target when it's used to treat Airway obstruction? | When used to treat Airway obstruction, the drug Fluticasone Furoate targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fluticasone furoate%" OR LOWER(tradeNames_list) L... | [{'UUID': 'DrugTargetsIndication121923_text_225658', 'drugName': 'Fluticasone Furoate', 'tradeNames_list': "['Arnuity ellipta', 'Avamys', 'Flonase sensimist allergy reliefRelvar ellipta', 'Trelegy ellipta', 'Veramyst']", 'syns_list': "['Allermist', 'Ennhale', 'Fluticasone furoate', 'Furamist', 'GSK 685 698GSK-685968', ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1414 | Q6 | What genes does Dasatinib target when it's used to treat ovarian cancer? | Dasatinib has not been approved by the FDA as a treatment for ovarian cancer, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are ABL1, BCR, HCK, SRC, LYN, KIT, PDGFRB, EPHA2, FRK, FYN, LCK, YES1, BLK, FGR, and SRMS. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dasatinib%" OR LOWER(tradeNames_list) LIKE "%dasa... | [{'UUID': 'DrugTargetsIndication121923_text_713549', 'drugName': 'Dasatinib', 'tradeNames_list': "['Dasatinib', 'Sprycel']", 'syns_list': "['BMS-354825', 'BMS-354825 HYDRATE', 'BMS-354825-03', 'DasatinibDasatinib anhydrous', 'Dasatinib hydrate', 'Dasatinib monohydrateNSC-759877']", 'target': 'ENSG00000097007', 'approve... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1751 | Q6 | What genes does Donepezil Hydrochloride target when it's used to treat Dementia? | When used to treat Dementia, the drug Donepezil Hydrochloride targets the gene ACHE. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%donepezil hydrochloride%" OR LOWER(tradeNames_lis... | [{'UUID': 'DrugTargetsIndication121923_text_993835', 'drugName': 'Donepezil Hydrochloride', 'tradeNames_list': "['Adlarity', 'Aricept', 'Aricept evess', 'Aricept odtDonepezil hydrochloride']", 'syns_list': "['Adlarity', 'BNAG', 'Donepezil hcl', 'Donepezil hydrochloride', 'E-2020E2020', 'NSC-737535', 'NSC-758882']", 'ta... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.457 | Q6 | What genes does Fluocinolone Acetonide target when it's used to treat seborrheic dermatitis? | When used to treat seborrheic dermatitis, the drug Fluocinolone Acetonide targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fluocinolone acetonide%" OR LOWER(tradeNames_list... | [{'UUID': 'DrugTargetsIndication121923_text_242240', 'drugName': 'Fluocinolone Acetonide', 'tradeNames_list': "['Capex', 'Derma-smoothe/fs', 'Dermotic', 'Fluocet', 'Fluocinolone acetonideFluonid', 'Fluotrex', 'Fs shampoo', 'Iluvien', 'Retisert', 'SynalarSynalar fte', 'Synalar-c', 'Synalar-hp', 'Synalar-n', 'Synandone',... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.496 | Q6 | What genes does Brexpiprazole target when it's used to treat major depressive disorder? | When used to treat major depressive disorder, the drug Brexpiprazole targets the genes DRD2, HTR2A, and HTR1A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%brexpiprazole%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_155834', 'drugName': 'Brexpiprazole', 'tradeNames_list': "['Rexulti']", 'syns_list': "['Brexpiprazole', 'OPC-34712']", 'target': 'ENSG00000149295', 'approvedSymbol': 'DRD2', 'approvedName': 'dopamine receptor D2', 'mesh_heading': 'Depressive Disorder, Major', 'efo_term': 'maj... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1482 | Q6 | What genes does Bromocriptine Mesylate target when it's used to treat type 2 diabetes mellitus? | When used to treat type 2 diabetes mellitus, the drug Bromocriptine Mesylate targets the genes DRD2, DRD3, and DRD4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%bromocriptine mesylate%" OR LOWER(tradeNames_list... | [{'UUID': 'DrugTargetsIndication121923_text_201378', 'drugName': 'Bromocriptine Mesylate', 'tradeNames_list': "['Bromocriptine mesylate', 'Cycloset', 'Parlodel']", 'syns_list': "['2-bromoergocryptine mesylate', 'Bromocriptine mesilateBromocriptine mesylate', 'Bromocriptine methanesulfonate', 'CB-154CB-154 MESYLATE', 'C... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.291 | Q6 | What genes does Fenfluramine Hydrochloride target when it's used to treat Seizure? | When used to treat Seizure, the drug Fenfluramine Hydrochloride targets the genes HTR2C, HTR1D, and SIGMAR1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fenfluramine hydrochloride%" OR LOWER(tradeNames_... | [{'UUID': 'DrugTargetsIndication121923_text_155525', 'drugName': 'Fenfluramine Hydrochloride', 'tradeNames_list': "['Fintepla', 'Ponderax', 'Ponderax pacaps', 'Pondimin']", 'syns_list': "['AHR-3002', 'Dl-fenfluramine hydrochloride', 'Fenfluramine hclFenfluramine hydrochloride', 'Ganal', 'HHR-965']", 'target': 'ENSG0000... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1817 | Q6 | What genes does Methylphenidate target when it's used to treat post-operative sign or symptom? | Methylphenidate has not been approved by the FDA as a treatment for post-operative sign or symptom, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are SLC6A2 and SLC6A3. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%methylphenidate%" OR LOWER(tradeNames_list) LIKE ... | [{'UUID': 'DrugTargetsIndication121923_text_439339', 'drugName': 'Methylphenidate', 'tradeNames_list': "['Concerta', 'Cotempla xr-odt', 'Daytrana']", 'syns_list': "['Concerta', 'Methylin', 'MethylphenidateMethylphenidate extended release', 'Prc-063', 'Threo-dl-methylphenidate']", 'target': 'ENSG00000103546', 'approvedS... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1986 | Q6 | What genes does Ibuprofen target when it's used to treat arthritis? | When used to treat arthritis, the drug Ibuprofen targets the genes PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ibuprofen%" OR LOWER(tradeNames_list) LIKE "%ibup... | [{'UUID': 'DrugTargetsIndication121923_text_840479', 'drugName': 'Ibuprofen', 'tradeNames_list': '[\'Aches-n-pain\', \'Advil\', \'Advil liqui-gels\', \'Advil migraine liqui-gelsAnadin joint pain\', \'Anadin liquifast\', \'Anadin period pain reliefAnadin ultra\', \'Apsifen\', \'Apsifen-f\', \'Arthrofen 200\', \'Arthrofe... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1370 | Q6 | What genes does Dexamethasone target when it's used to treat mycosis fungoides? | When used to treat mycosis fungoides, the drug Dexamethasone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dexamethasone%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_227792', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.893 | Q6 | What genes does Vutrisiran target when it's used to treat polyneuropathy? | When used to treat polyneuropathy, the drug Vutrisiran targets the gene TTR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%vutrisiran%" OR LOWER(tradeNames_list) LIKE "%vut... | [{'UUID': 'DrugTargetsIndication121923_text_1097671', 'drugName': 'Vutrisiran', 'tradeNames_list': "['Amvuttra']", 'syns_list': "['ALN-65492', 'ALN-TTRSC02', 'Votrisiran', 'Vutrisiran']", 'target': 'ENSG00000118271', 'approvedSymbol': 'TTR', 'approvedName': 'transthyretin', 'mesh_heading': 'Polyneuropathies', 'efo_term... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1063 | Q6 | What genes does Vorapaxar Sulfate target when it's used to treat stroke? | When used to treat stroke, the drug Vorapaxar Sulfate targets the gene F2R. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%vorapaxar sulfate%" OR LOWER(tradeNames_list) LIK... | [{'UUID': 'DrugTargetsIndication121923_text_1193355', 'drugName': 'Vorapaxar Sulfate', 'tradeNames_list': "['Zontivity']", 'syns_list': "['SCH 530348', 'SCH-530348', 'Vorapaxar sulfate']", 'target': 'ENSG00000181104', 'approvedSymbol': 'F2R', 'approvedName': 'coagulation factor II thrombin receptor', 'mesh_heading': 'S... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1846 | Q6 | What genes does Buprenorphine target when it's used to treat drug dependence? | When used to treat drug dependence, the drug Buprenorphine targets the genes OPRM1 and OPRK1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%buprenorphine%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_764504', 'drugName': 'Buprenorphine', 'tradeNames_list': "['Bupeaze', 'Buplast', 'Butec', 'Butrans', 'Hapoctasin', 'Panitaz', 'PrenotrixReletrans', 'Sevodyne', 'Sublocade', 'Temgesic', 'Tephine', 'Transtec']", 'syns_list': "['ALKS-5461 COMPONENT BUPRENORPHINE', 'Brixadi', 'Bu... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1982 | Q6 | What genes does Dexmedetomidine Hydrochloride target when it's used to treat spinal cord cancer? | Dexmedetomidine Hydrochloride has not been approved by the FDA as a treatment for spinal cord cancer, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are ADRA2A, ADRA2C, and ADRA2B. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dexmedetomidine hydrochloride%" OR LOWER(tradeNam... | [{'UUID': 'DrugTargetsIndication121923_text_1025774', 'drugName': 'Dexmedetomidine Hydrochloride', 'tradeNames_list': "['Dexmedetomidine hydrochloride', 'Igalmi', 'Precedex']", 'syns_list': "['Cepedex', 'Dexdomitor', 'Dexdor', 'Dexmedetomidine hclDexmedetomidine hydrochloride', 'Igalmi', 'Sedadex', 'Sileo']", 'target':... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.789 | Q6 | What genes does Azelastine Hydrochloride target when it's used to treat Nasal congestion? | When used to treat Nasal congestion, the drug Azelastine Hydrochloride targets the gene HRH1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%azelastine hydrochloride%" OR LOWER(tradeNames_li... | [{'UUID': 'DrugTargetsIndication121923_text_455905', 'drugName': 'Azelastine Hydrochloride', 'tradeNames_list': '[\'Astelin\', \'Astepro\', \'Astepro allergy\', "Azelastine hydrochlorideChildren\'s astepro allergyOptilast", \'Optivar\', \'RhinolastRhinolast allergy\']', 'syns_list': "['A-5610', 'Azelastine hcl', 'Azela... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.866 | Q6 | What genes does Encorafenib target when it's used to treat neoplasm? | When used to treat neoplasm, the drug Encorafenib targets the gene BRAF. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%encorafenib%" OR LOWER(tradeNames_list) LIKE "%en... | [{'UUID': 'DrugTargetsIndication121923_text_752291', 'drugName': 'Encorafenib', 'tradeNames_list': "['Braftovi']", 'syns_list': "['Encorafenib', 'Lgx-818', 'Lgx818', 'NVP-LGX-818-NXA', 'NVP-LGX818NVP-LGX818-NXA']", 'target': 'ENSG00000157764', 'approvedSymbol': 'BRAF', 'approvedName': 'B-Raf proto-oncogene, serine/thre... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1306 | Q6 | What genes does Hydrocortisone target when it's used to treat hypotension? | Hydrocortisone has not been approved by the FDA as a treatment for hypotension, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%hydrocortisone%" OR LOWER(tradeNames_list) LIKE "... | [{'UUID': 'DrugTargetsIndication121923_text_241199', 'drugName': 'Hydrocortisone', 'tradeNames_list': "['Acetasol hc', 'Acticort', 'Aeroseb-hc', 'Ala-cort', 'Ala-scalpAlkindi sprinkle', 'Alphaderm', 'Anflam', 'Anucort-Hc', 'Anugesic hcAnusol hc', 'Anusol plus hc', 'Anusol soothing relief', 'Anusol-HcBalneol-hc', 'Beta-... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1088 | Q6 | What genes does Lubiprostone target when it's used to treat Chronic pain? | When used to treat Chronic pain, the drug Lubiprostone targets the gene CLCN2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lubiprostone%" OR LOWER(tradeNames_list) LIKE "%l... | [{'UUID': 'DrugTargetsIndication121923_text_1193410', 'drugName': 'Lubiprostone', 'tradeNames_list': "['Amitiza']", 'syns_list': "['Lubiprostone', 'RU-0211']", 'target': 'ENSG00000114859', 'approvedSymbol': 'CLCN2', 'approvedName': 'chloride voltage-gated channel 2', 'mesh_heading': 'Chronic Pain', 'efo_term': 'Chronic... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1889 | Q6 | What genes does Diazepam target when it's used to treat anxiety disorder? | When used to treat anxiety disorder, the drug Diazepam targets the genes GABRA1, GABRB2, GABRG2, GABRB3, GABRA4, GABRG3, GABRQ, GABRA3, GABRP, GABRD, GABRG1, GABRB1, GABRE, GABRA2, GABRA5, and GABRA6. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%diazepam%" OR LOWER(tradeNames_list) LIKE "%diaze... | [{'UUID': 'DrugTargetsIndication121923_text_960228', 'drugName': 'Diazepam', 'tradeNames_list': "['Alupram 10', 'Alupram 2', 'Alupram 5', 'Apozepam', 'Atensine', 'DialarDialar fte', 'Diastat', 'Diastat acudial', 'Diazepam', 'Diazepam intensolDizac', 'E-Pam', 'Paxel', 'Q-pam', 'Relanium', 'Scriptopam', 'SerenackSolis', ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.331 | Q6 | What genes does Panobinostat target when it's used to treat neoplasm? | When used to treat neoplasm, the drug Panobinostat targets the genes HDAC1, HDAC3, HDAC6, HDAC2, HDAC5, HDAC7, HDAC8, HDAC11, HDAC4, HDAC9, and HDAC10. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%panobinostat%" OR LOWER(tradeNames_list) LIKE "%p... | [{'UUID': 'DrugTargetsIndication121923_text_1082388', 'drugName': 'Panobinostat', 'tradeNames_list': "['Farydak']", 'syns_list': "['LBH-589', 'LBH589', 'Panobinostat', 'Panobinostat hydrate']", 'target': 'ENSG00000061273', 'approvedSymbol': 'HDAC7', 'approvedName': 'histone deacetylase 7', 'mesh_heading': 'Neoplasms', ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.448 | Q6 | What genes does Clonidine target when it's used to treat hypertension? | When used to treat hypertension, the drug Clonidine targets the genes ADRA2A, ADRA2C, and ADRA2B. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%clonidine%" OR LOWER(tradeNames_list) LIKE "%clon... | [{'UUID': 'DrugTargetsIndication121923_text_1033830', 'drugName': 'Clonidine', 'tradeNames_list': "['Catapres', 'Catapres-tts-1', 'Catapres-tts-2', 'Catapres-tts-3', 'ClonidineNexiclon xr']", 'syns_list': "['Catapres', 'Catarpres-tts', 'Clonidine', 'Clonidine extended releaseClorpres', 'Combipres', 'Duraclon', 'ST-155-... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.766 | Q6 | What genes does Aspirin target when it's used to treat coronary artery disease? | When used to treat coronary artery disease, the drug Aspirin targets the genes PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%aspirin%" OR LOWER(tradeNames_list) LIKE "%aspiri... | [{'UUID': 'DrugTargetsIndication121923_text_834433', 'drugName': 'Aspirin', 'tradeNames_list': "['8-hour bayer', 'Acetosalic Acid', 'Acetylsalic acidAcetylsalicylic Acid', 'Alka rapid', 'Anadin all night', 'Angettes 75Aspirin', 'Aspro clr', 'Bayer extra strength aspirin for migraine painDanamep', 'Disprin cv', 'Disprin... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1844 | Q6 | What genes does Famotidine target when it's used to treat osteoarthritis? | When used to treat osteoarthritis, the drug Famotidine targets the gene HRH2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%famotidine%" OR LOWER(tradeNames_list) LIKE "%fam... | [{'UUID': 'DrugTargetsIndication121923_text_1100339', 'drugName': 'Famotidine', 'tradeNames_list': "['Famotidine', 'Famotidine preservative freeFamotidine preservative free (pharmacy bulk)', 'Fluxid', 'PepcidPepcid ac', 'Pepcid preservative free', 'Pepcid rpd']", 'syns_list': "['Amfamox', 'Fadul', 'Famodil', 'Famosan',... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.913 | Q6 | What genes does Prednisone target when it's used to treat eosinophilic pneumonia? | When used to treat eosinophilic pneumonia, the drug Prednisone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%prednisone%" OR LOWER(tradeNames_list) LIKE "%pre... | [{'UUID': 'DrugTargetsIndication121923_text_218694', 'drugName': 'Prednisone', 'tradeNames_list': "['Cortan', 'Cortancyl', 'Decortisyl', 'Delta-dome', 'Deltasone', 'FernisoneLiquid pred', 'Lodotra', 'Meticorten', 'Orasone', 'Paracort', 'Prednicen-mPrednisone', 'Prednisone intensol', 'Rayos', 'Servisone', 'Sterapred']",... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1141 | Q6 | What genes does Docetaxel target when it's used to treat prostate cancer? | Docetaxel has not been approved by the FDA as a treatment for prostate cancer, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are TUBB4B, TUBB1, TUBA3C, TUBA4A, TUBB3, TUBA1A, TUBB4A, TUBB8, TUBB, TUBA1B, TUBA1C, TUBA3E, TUBB2A, TUBB2B, and TUBB6. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%docetaxel%" OR LOWER(tradeNames_list) LIKE "%doce... | [{'UUID': 'DrugTargetsIndication121923_text_95701', 'drugName': 'Docetaxel', 'tradeNames_list': "['Docefrez', 'Docetaxel', 'Taxceus', 'Taxotere']", 'syns_list': "['Bind 014', 'CKD-810', 'Docetaxel', 'Docetaxel (as trihydrate)Docetaxel anhydrous', 'Docetaxel hydrate', 'Docetaxel trihydrateNSC-628503', 'RP 56976', 'RP-56... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.180 | Q6 | What genes does Bupivacaine Hydrochloride target when it's used to treat peritoneum cancer? | Bupivacaine Hydrochloride has not been approved by the FDA as a treatment for peritoneum cancer, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is SCN4A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%bupivacaine hydrochloride%" OR LOWER(tradeNames_l... | [{'UUID': 'DrugTargetsIndication121923_text_664026', 'drugName': 'Bupivacaine Hydrochloride', 'tradeNames_list': "['Bupivac hcl', 'Bupivacaine hydrochloride', 'Bupivacaine hydrochloride kitBupivacaine hydrochloride preservative free', 'Marcain', 'MarcaineMarcaine hydrochloride', 'Marcaine hydrochloride preservative fre... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.729 | Q6 | What genes does Alendronic Acid target when it's used to treat bone disease? | When used to treat bone disease, the drug Alendronic Acid targets the gene FDPS. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%alendronic acid%" OR LOWER(tradeNames_list) LIKE ... | [{'UUID': 'DrugTargetsIndication121923_text_1099503', 'drugName': 'Alendronate Sodium', 'tradeNames_list': "['Alendronate sodium', 'Binosto', 'Fosamax']", 'syns_list': "['Adrovance', 'Alendronate (as sodium)', 'Alendronate sodiumAlendronate sodium hydrate', 'Alendronate sodium trihydrateAlendronic acid monosodium salt ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1273 | Q6 | What genes does Opicapone target when it's used to treat Parkinson disease? | When used to treat Parkinson disease, the drug Opicapone targets the gene COMT. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%opicapone%" OR LOWER(tradeNames_list) LIKE "%opic... | [{'UUID': 'DrugTargetsIndication121923_text_1193366', 'drugName': 'Opicapone', 'tradeNames_list': "['Ongentys']", 'syns_list': "['BIA 9-1067', 'BIA-9-1067', 'BIA-91067', 'Ongentys', 'Opicapone']", 'target': 'ENSG00000093010', 'approvedSymbol': 'COMT', 'approvedName': 'catechol-O-methyltransferase', 'mesh_heading': 'Par... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.89 | Q6 | What genes does Clobetasol Propionate target when it's used to treat skin disease? | When used to treat skin disease, the drug Clobetasol Propionate targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%clobetasol propionate%" OR LOWER(tradeNames_list)... | [{'UUID': 'DrugTargetsIndication121923_text_243530', 'drugName': 'Clobetasol Propionate', 'tradeNames_list': "['Clarelux', 'Clobaderm', 'Clobetasol propionateClobetasol propionate (emollient)', 'Clobex', 'Cormax', 'DermovateDermovate nn', 'Embeline', 'Embeline e', 'Etrivex', 'Impeklo', 'ImpoyzOlux', 'Olux e', 'Temovate... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
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