uuid stringlengths 4 8 | template_uuid stringclasses 40
values | question stringlengths 13 193 | answer stringlengths 29 2.2k | benchmark_query stringlengths 133 622 | execution_results stringlengths 2 1.14M | query_type stringclasses 2
values | sql_category stringclasses 26
values | bio_category stringclasses 14
values |
|---|---|---|---|---|---|---|---|---|
Q6.1410 | Q6 | What genes does Dexamethasone target when it's used to treat nephrotic syndrome? | When used to treat nephrotic syndrome, the drug Dexamethasone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dexamethasone%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_227764', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1900 | Q6 | What genes does Simvastatin target when it's used to treat acute myocardial infarction? | When used to treat acute myocardial infarction, the drug Simvastatin targets the gene HMGCR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%simvastatin%" OR LOWER(tradeNames_list) LIKE "%si... | [{'UUID': 'DrugTargetsIndication121923_text_1103902', 'drugName': 'Simvastatin', 'tradeNames_list': "['Flolipid', 'Lacersa', 'Ranzolont', 'Simvador', 'Simvastatin', 'ZocorZocor heart-pro']", 'syns_list': "['C10AA01', 'MK-0733', 'MK-733', 'NSC-758706', 'SimvastatinSimvastatin hydroxy acid', 'Synvinolin']", 'target': 'EN... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.463 | Q6 | What genes does Fentanyl target when it's used to treat cancer? | When used to treat cancer, the drug Fentanyl targets the gene OPRM1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fentanyl%" OR LOWER(tradeNames_list) LIKE "%fenta... | [{'UUID': 'DrugTargetsIndication121923_text_786255', 'drugName': 'Fentanyl', 'tradeNames_list': "['Abstral', 'Actiq', 'Breakyl', 'Duragesic', 'Duragesic-100', 'Duragesic-12Duragesic-25', 'Duragesic-37', 'Duragesic-50', 'Duragesic-75', 'DurogesicDurogesic dtrans', 'Effentora', 'Fencino', 'Fentalis reservoirFentanyl-100'... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1830 | Q6 | What genes does Clozapine target when it's used to treat intellectual disability? | Clozapine has not been approved by the FDA as a treatment for intellectual disability, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are DRD2 and HTR2A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%clozapine%" OR LOWER(tradeNames_list) LIKE "%cloz... | [{'UUID': 'DrugTargetsIndication121923_text_157980', 'drugName': 'Clozapine', 'tradeNames_list': "['Clozapine', 'Clozaril', 'Fazaclo', 'Fazaclo odt', 'Versacloz', 'Zaponex']", 'syns_list': "['Clozapine', 'Clozapine (caraco)', 'Clozapine (clozaril)Clozapine (fazaclo)', 'Clozapine (ivax)', 'Clozapine (mylan)Clozapine (te... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.55 | Q6 | What genes does Vutrisiran target when it's used to treat familial amyloid neuropathy? | When used to treat familial amyloid neuropathy, the drug Vutrisiran targets the gene TTR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%vutrisiran%" OR LOWER(tradeNames_list) LIKE "%vut... | [{'UUID': 'DrugTargetsIndication121923_text_1097670', 'drugName': 'Vutrisiran', 'tradeNames_list': "['Amvuttra']", 'syns_list': "['ALN-65492', 'ALN-TTRSC02', 'Votrisiran', 'Vutrisiran']", 'target': 'ENSG00000118271', 'approvedSymbol': 'TTR', 'approvedName': 'transthyretin', 'mesh_heading': 'Amyloid Neuropathies, Famili... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1503 | Q6 | What genes does Mesalamine target when it's used to treat diverticulitis? | Mesalamine has not been approved by the FDA as a treatment for diverticulitis, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are PTGS2, PTGS1, PPARG, and ALOX5. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%mesalamine%" OR LOWER(tradeNames_list) LIKE "%mes... | [{'UUID': 'DrugTargetsIndication121923_text_842713', 'drugName': 'Mesalamine', 'tradeNames_list': "['Apriso', 'Asacol', 'Asacol hd', 'Canasa', 'Coltec ec', 'Delzicol', 'IpocolLialda', 'Mesalamine', 'Mesren mr', 'Mezavant xl', 'Octasa', 'PentasaPentasa sr', 'Rowasa', 'Salofalk', 'Sfrowasa']", 'syns_list': "['Benzoic aci... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.650 | Q6 | What genes does Tiotropium Bromide target when it's used to treat chronic bronchitis? | When used to treat chronic bronchitis, the drug Tiotropium Bromide targets the gene CHRM3. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%tiotropium bromide%" OR LOWER(tradeNames_list) LI... | [{'UUID': 'DrugTargetsIndication121923_text_857915', 'drugName': 'Tiotropium Bromide', 'tradeNames_list': "['Spiriva', 'Spiriva respimat']", 'syns_list': "['BA 679 BR', 'BA-679 BR', 'BA-679-BR', 'BA-679BR', 'Tiotropium bromideTiotropium bromide anhydrous', 'Tiotropium bromide hydrateTiotropium bromide monohydrate']", '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.684 | Q6 | What genes does Palbociclib target when it's used to treat glioblastoma multiforme? | Palbociclib has not been approved by the FDA as a treatment for glioblastoma multiforme, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are CDK4, CDK6, and CCND1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%palbociclib%" OR LOWER(tradeNames_list) LIKE "%pa... | [{'UUID': 'DrugTargetsIndication121923_text_851538', 'drugName': 'Palbociclib', 'tradeNames_list': "['Ibrance']", 'syns_list': "['PD-0332991', 'Palbociclib']", 'target': 'ENSG00000135446', 'approvedSymbol': 'CDK4', 'approvedName': 'cyclin dependent kinase 4', 'mesh_heading': 'Glioblastoma', 'efo_term': 'glioblastoma mu... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.224 | Q6 | What genes does Tiotropium Bromide target when it's used to treat chronic obstructive pulmonary disease? | When used to treat chronic obstructive pulmonary disease, the drug Tiotropium Bromide targets the gene CHRM3. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%tiotropium bromide%" OR LOWER(tradeNames_list) LI... | [{'UUID': 'DrugTargetsIndication121923_text_857913', 'drugName': 'Tiotropium Bromide', 'tradeNames_list': "['Spiriva', 'Spiriva respimat']", 'syns_list': "['BA 679 BR', 'BA-679 BR', 'BA-679-BR', 'BA-679BR', 'Tiotropium bromideTiotropium bromide anhydrous', 'Tiotropium bromide hydrateTiotropium bromide monohydrate']", '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.116 | Q6 | What genes does Albuterol target when it's used to treat chronic obstructive pulmonary disease? | When used to treat chronic obstructive pulmonary disease, the drug Albuterol targets the gene ADRB2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%albuterol%" OR LOWER(tradeNames_list) LIKE "%albu... | [{'UUID': 'DrugTargetsIndication121923_text_936247', 'drugName': 'Albuterol Sulfate', 'tradeNames_list': "['Accuneb', 'Albuterol sulfate', 'Proair', 'Proair digihaler', 'Proair hfaProair respiclick', 'Proventil', 'Proventil-hfa', 'Ventolin', 'Ventolin hfaVentolin rotacaps', 'Volmax', 'Vospire er']", 'syns_list': "['Alb... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1552 | Q6 | What genes does Olaparib target when it's used to treat cancer? | When used to treat cancer, the drug Olaparib targets the genes PARP2, PARP1, and PARP3. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%olaparib%" OR LOWER(tradeNames_list) LIKE "%olapa... | [{'UUID': 'DrugTargetsIndication121923_text_797332', 'drugName': 'Olaparib', 'tradeNames_list': "['Lynparza']", 'syns_list': "['AZ-2281', 'AZ2281', 'AZD-2281', 'AZD2281', 'KEYLYNK-010 COMPONENT OLAPARIBKU-0059436', 'KU-59436', 'NSC-747856', 'OLAPARIB COMPONENT OF KEYLYNK-010Olaparib']", 'target': 'ENSG00000129484', 'ap... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1303 | Q6 | What genes does Pitavastatin Calcium target when it's used to treat hyperlipidemia? | When used to treat hyperlipidemia, the drug Pitavastatin Calcium targets the gene HMGCR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%pitavastatin calcium%" OR LOWER(tradeNames_list) ... | [{'UUID': 'DrugTargetsIndication121923_text_1104278', 'drugName': 'Pitavastatin Calcium', 'tradeNames_list': "['Livalo', 'Pitavastatin calcium']", 'syns_list': "['Itavastatin calcium', 'NK-104', 'Pitavastatin CalciumPitavastatin calcium', 'Pitavastatin calcium salt']", 'target': 'ENSG00000113161', 'approvedSymbol': 'HM... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.987 | Q6 | What genes does Ibrutinib target when it's used to treat Waldenstrom macroglobulinemia? | When used to treat Waldenstrom macroglobulinemia, the drug Ibrutinib targets the gene BTK. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ibrutinib%" OR LOWER(tradeNames_list) LIKE "%ibru... | [{'UUID': 'DrugTargetsIndication121923_text_995128', 'drugName': 'Ibrutinib', 'tradeNames_list': "['Imbruvica']", 'syns_list': "['CRA-032765', 'Ibrutinib', 'PC-32765', 'PCI 32765', 'PCI-32765PCI-32765-00']", 'target': 'ENSG00000010671', 'approvedSymbol': 'BTK', 'approvedName': 'Bruton tyrosine kinase', 'mesh_heading': ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.177 | Q6 | What genes does Nitroglycerin target when it's used to treat cardiovascular disease? | When used to treat cardiovascular disease, the drug Nitroglycerin targets the genes GUCY1B1, GUCY1B2, GUCY1A2, and GUCY1A1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%nitroglycerin%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_972644', 'drugName': 'Nitroglycerin', 'tradeNames_list': "['Coro-nitro', 'Deponit 10', 'Deponit 5', 'Glytrin', 'Gonitro', 'Lenitral 7.5Minitran', 'Minitran 10', 'Minitran 15', 'Minitran 5', 'NatiroseNitriderm tts', 'Nitro iv', 'Nitro-bid', 'Nitro-dur', 'Nitro-mack retNitrocin... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1650 | Q6 | What genes does Alendronate Sodium target when it's used to treat osteitis deformans? | When used to treat osteitis deformans, the drug Alendronate Sodium targets the gene FDPS. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%alendronate sodium%" OR LOWER(tradeNames_list) LI... | [{'UUID': 'DrugTargetsIndication121923_text_1099492', 'drugName': 'Alendronate Sodium', 'tradeNames_list': "['Alendronate sodium', 'Binosto', 'Fosamax']", 'syns_list': "['Adrovance', 'Alendronate (as sodium)', 'Alendronate sodiumAlendronate sodium hydrate', 'Alendronate sodium trihydrateAlendronic acid monosodium salt ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.596 | Q6 | What genes does Memantine Hydrochloride target when it's used to treat Dementia? | When used to treat Dementia, the drug Memantine Hydrochloride targets the genes GRIN1, GRIN2A, GRIN2B, GRIN2D, GRIN3B, GRIN2C, and GRIN3A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%memantine hydrochloride%" OR LOWER(tradeNames_lis... | [{'UUID': 'DrugTargetsIndication121923_text_455455', 'drugName': 'Memantine Hydrochloride', 'tradeNames_list': "['Akatinol', 'Ebixa', 'Marixino', 'Memantine', 'Memantine hydrochlorideNamenda', 'Namenda xr', 'Nemdatine', 'Valios']", 'syns_list': "['Acrescent', 'Auxura', 'Balaxur', 'FP-01', 'Memantine accord', 'Memantine... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1560 | Q6 | What genes does Istradefylline target when it's used to treat Parkinson disease? | When used to treat Parkinson disease, the drug Istradefylline targets the gene ADORA2A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%istradefylline%" OR LOWER(tradeNames_list) LIKE "... | [{'UUID': 'DrugTargetsIndication121923_text_695359', 'drugName': 'Istradefylline', 'tradeNames_list': "['Nourianz']", 'syns_list': "['Istradefylline', 'KW-6002', 'Nouriast']", 'target': 'ENSG00000128271', 'approvedSymbol': 'ADORA2A', 'approvedName': 'adenosine A2a receptor', 'mesh_heading': 'Parkinson Disease', 'efo_te... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.19 | Q6 | What genes does Paclitaxel target when it's used to treat oropharyngeal carcinoma? | Paclitaxel has not been approved by the FDA as a treatment for oropharyngeal carcinoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are TUBB4B, TUBB1, TUBA3C, TUBA4A, TUBB3, TUBA1A, TUBB4A, TUBB8, TUBB, TUBA1B, TUBA1C, TUBA3E, TUBB2A, TUBB2B, and TUBB6. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%paclitaxel%" OR LOWER(tradeNames_list) LIKE "%pac... | [{'UUID': 'DrugTargetsIndication121923_text_853', 'drugName': 'Paclitaxel', 'tradeNames_list': "['Abraxane', 'Pacitaxel', 'Paclitaxel', 'Paxene', 'Taxol', 'Taxol 100']", 'syns_list': "['(-)-paclitaxel', 'ABI-007', 'ABI-007 COMPONENT PACLITAXEL', 'BMS 181339-01BMS-181339-01', 'Capxol', 'Cyclopax', 'DHP 107', 'DHP-107', ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.429 | Q6 | What genes does Ibuprofen target when it's used to treat cardiovascular disease? | When used to treat cardiovascular disease, the drug Ibuprofen targets the genes PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ibuprofen%" OR LOWER(tradeNames_list) LIKE "%ibup... | [{'UUID': 'DrugTargetsIndication121923_text_840161', 'drugName': 'Ibuprofen', 'tradeNames_list': '[\'Aches-n-pain\', \'Advil\', \'Advil liqui-gels\', \'Advil migraine liqui-gelsAnadin joint pain\', \'Anadin liquifast\', \'Anadin period pain reliefAnadin ultra\', \'Apsifen\', \'Apsifen-f\', \'Arthrofen 200\', \'Arthrofe... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1345 | Q6 | What genes does Aspirin target when it's used to treat toothache? | When used to treat toothache, the drug Aspirin targets the genes PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%aspirin%" OR LOWER(tradeNames_list) LIKE "%aspiri... | [{'UUID': 'DrugTargetsIndication121923_text_834440', 'drugName': 'Aspirin', 'tradeNames_list': "['8-hour bayer', 'Acetosalic Acid', 'Acetylsalic acidAcetylsalicylic Acid', 'Alka rapid', 'Anadin all night', 'Angettes 75Aspirin', 'Aspro clr', 'Bayer extra strength aspirin for migraine painDanamep', 'Disprin cv', 'Disprin... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.289 | Q6 | What genes does Lifitegrast target when it's used to treat dry eye syndrome? | When used to treat dry eye syndrome, the drug Lifitegrast targets the genes ITGAL and ITGB2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lifitegrast%" OR LOWER(tradeNames_list) LIKE "%li... | [{'UUID': 'DrugTargetsIndication121923_text_1053376', 'drugName': 'Lifitegrast', 'tradeNames_list': "['Xiidra']", 'syns_list': "['Lifitegrast', 'SAR 1118', 'SAR-1118', 'SHP-606', 'SHP606']", 'target': 'ENSG00000005844', 'approvedSymbol': 'ITGAL', 'approvedName': 'integrin subunit alpha L', 'mesh_heading': 'Dry Eye Synd... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1584 | Q6 | What genes does Telmisartan target when it's used to treat cardiovascular disease? | When used to treat cardiovascular disease, the drug Telmisartan targets the gene AGTR1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%telmisartan%" OR LOWER(tradeNames_list) LIKE "%te... | [{'UUID': 'DrugTargetsIndication121923_text_1072708', 'drugName': 'Telmisartan', 'tradeNames_list': "['Micardis', 'Telmisartan', 'Tolura']", 'syns_list': "['BIBR 277 SE', 'BIBR-277', 'BIBR-277 SE', 'BIBR-277-SE', 'BIBR-277SEC09CA07', 'Kinzalmono', 'Pritor', 'Semintra', 'TelmisartanTelmisartan actavis', 'Telmisartan tev... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.434 | Q6 | What genes does Vorinostat target when it's used to treat Cutaneous T-cell lymphoma? | When used to treat Cutaneous T-cell lymphoma, the drug Vorinostat targets the genes HDAC1, HDAC3, HDAC6, and HDAC2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%vorinostat%" OR LOWER(tradeNames_list) LIKE "%vor... | [{'UUID': 'DrugTargetsIndication121923_text_1077139', 'drugName': 'Vorinostat', 'tradeNames_list': "['Zolinza']", 'syns_list': "['MK-0683', 'MK0683', 'NSC-701852', 'NSC-748799', 'NSC-759852Suberoylanilide hydroxamic acid', 'Vorinostat']", 'target': 'ENSG00000116478', 'approvedSymbol': 'HDAC1', 'approvedName': 'histone ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1640 | Q6 | What genes does Vandetanib target when it's used to treat ovarian cancer? | Vandetanib has not been approved by the FDA as a treatment for ovarian cancer, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are EGFR, ERBB3, KDR, SRC, TEK, ERBB2, FLT1, FLT4, EPHA2, RET, ERBB4, EPHB4, PTK6, EPHB2, EPHA5, EPHA4, EPHA8, EPHA6, EPHA7, EPHB3, EPHA... | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%vandetanib%" OR LOWER(tradeNames_list) LIKE "%van... | [{'UUID': 'DrugTargetsIndication121923_text_210177', 'drugName': 'Vandetanib', 'tradeNames_list': "['Caprelsa', 'Zactima']", 'syns_list': "['GNF-PF-2188', 'NSC-744325', 'NSC-760766', 'Vandetanib', 'ZD-64', 'ZD-6474ZD6474']", 'target': 'ENSG00000146648', 'approvedSymbol': 'EGFR', 'approvedName': 'epidermal growth factor... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1245 | Q6 | What genes does Darolutamide target when it's used to treat prostate carcinoma? | When used to treat prostate carcinoma, the drug Darolutamide targets the gene AR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%darolutamide%" OR LOWER(tradeNames_list) LIKE "%d... | [{'UUID': 'DrugTargetsIndication121923_text_924425', 'drugName': 'Darolutamide', 'tradeNames_list': "['Nubeqa']", 'syns_list': "['BAY 1841788', 'BAY-1841788', 'BAY1841788', 'Darolutamide', 'ODM-201Odm-201']", 'target': 'ENSG00000169083', 'approvedSymbol': 'AR', 'approvedName': 'androgen receptor', 'mesh_heading': 'Pros... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.676 | Q6 | What genes does Ertugliflozin target when it's used to treat diabetes mellitus? | When used to treat diabetes mellitus, the drug Ertugliflozin targets the gene SLC5A2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ertugliflozin%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_1096239', 'drugName': 'Ertugliflozin', 'tradeNames_list': "['Steglatro']", 'syns_list': "['Ertugliflozin', 'Ertugliflozin l-pyroglutamic acidErtugliflozin pidolate', 'MK-8835', 'PF-04971729', 'PF-04971729-00PF04971729', 'Pf-04971729']", 'target': 'ENSG00000140675', 'approvedS... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.32 | Q6 | What genes does Aprepitant target when it's used to treat post operative nausea and vomiting? | When used to treat post operative nausea and vomiting, the drug Aprepitant targets the gene TACR1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%aprepitant%" OR LOWER(tradeNames_list) LIKE "%apr... | [{'UUID': 'DrugTargetsIndication121923_text_1072874', 'drugName': 'Aprepitant', 'tradeNames_list': "['Aprepitant', 'Cinvanti', 'Emend']", 'syns_list': "['Aprepitant', 'L-754,030', 'MK-0869', 'MK-869', 'NSC-748825']", 'target': 'ENSG00000115353', 'approvedSymbol': 'TACR1', 'approvedName': 'tachykinin receptor 1', 'mesh_... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.934 | Q6 | What genes does Topotecan Hydrochloride target when it's used to treat leukemia? | Topotecan Hydrochloride has not been approved by the FDA as a treatment for leukemia, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is TOP1MT. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%topotecan hydrochloride%" OR LOWER(tradeNames_lis... | [{'UUID': 'DrugTargetsIndication121923_text_1193555', 'drugName': 'Topotecan Hydrochloride', 'tradeNames_list': "['Hycamptin', 'Hycamtin', 'Topotecan', 'Topotecan hydrochloride']", 'syns_list': "['Evotopin', 'NSC-759263', 'Nogitecan hydrochloride', 'SK&F S-104864-ASK&F-S-104864A', 'SK-S-104864-A', 'Topotecan (as hydroc... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.982 | Q6 | What genes does Pemetrexed Disodium target when it's used to treat non-small cell lung carcinoma? | When used to treat non-small cell lung carcinoma, the drug Pemetrexed Disodium targets the genes TYMS, GART, and DHFR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%pemetrexed disodium%" OR LOWER(tradeNames_list) L... | [{'UUID': 'DrugTargetsIndication121923_text_918419', 'drugName': 'Pemetrexed Disodium', 'tradeNames_list': "['Alimta']", 'syns_list': "['LY-231514 DISODIUM SALT', 'LY231514 DISODIUM SALT', 'Pemetrexed disodiumPemetrexed disodium heptahydrate', 'Pemetrexed sodium hydratePemetrexed sodium salt']", 'target': 'ENSG00000228... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.217 | Q6 | What genes does Cannabidiol target when it's used to treat hamartoma? | When used to treat hamartoma, the drug Cannabidiol targets the gene CNR1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%cannabidiol%" OR LOWER(tradeNames_list) LIKE "%ca... | [{'UUID': 'DrugTargetsIndication121923_text_1073763', 'drugName': 'Cannabidiol', 'tradeNames_list': "['Epidiolex']", 'syns_list': "['(-)-cannabidiol', '(-)-cbd', '(-)-trans-cannabidiol.delta.1(2)-trans-cannabidiol', 'BTX-1204', 'BTX-1503', 'CBD', 'CannabidiolCannabidiol solution', 'Cardiolrx', 'GWP-42003', 'GWP-42003-P... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1130 | Q6 | What genes does Alendronate Sodium target when it's used to treat metabolic disease? | When used to treat metabolic disease, the drug Alendronate Sodium targets the gene FDPS. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%alendronate sodium%" OR LOWER(tradeNames_list) LI... | [{'UUID': 'DrugTargetsIndication121923_text_1099489', 'drugName': 'Alendronate Sodium', 'tradeNames_list': "['Alendronate sodium', 'Binosto', 'Fosamax']", 'syns_list': "['Adrovance', 'Alendronate (as sodium)', 'Alendronate sodiumAlendronate sodium hydrate', 'Alendronate sodium trihydrateAlendronic acid monosodium salt ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.330 | Q6 | What genes does Tolvaptan target when it's used to treat Hyponatremia? | When used to treat Hyponatremia, the drug Tolvaptan targets the gene AVPR2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%tolvaptan%" OR LOWER(tradeNames_list) LIKE "%tolv... | [{'UUID': 'DrugTargetsIndication121923_text_695168', 'drugName': 'Tolvaptan', 'tradeNames_list': "['Jinarc', 'Jynarque', 'Samsca']", 'syns_list': "['OPC-41061', 'OPC-41061(TOLVAPTAN)', 'Tolvaptan']", 'target': 'ENSG00000126895', 'approvedSymbol': 'AVPR2', 'approvedName': 'arginine vasopressin receptor 2', 'mesh_heading... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.566 | Q6 | What genes does Zanubrutinib target when it's used to treat cancer? | When used to treat cancer, the drug Zanubrutinib targets the gene BTK. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%zanubrutinib%" OR LOWER(tradeNames_list) LIKE "%z... | [{'UUID': 'DrugTargetsIndication121923_text_1025173', 'drugName': 'Zanubrutinib', 'tradeNames_list': "['Brukinsa']", 'syns_list': "['BGB-3111', 'Bgb-3111', 'Zanubrutinib']", 'target': 'ENSG00000010671', 'approvedSymbol': 'BTK', 'approvedName': 'Bruton tyrosine kinase', 'mesh_heading': 'Neoplasms', 'efo_term': 'cancer',... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1112 | Q6 | What genes does Lidocaine target when it's used to treat Tendinopathy? | When used to treat Tendinopathy, the drug Lidocaine targets the genes SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lidocaine%" OR LOWER(tradeNames_list) LIKE "%lido... | [{'UUID': 'DrugTargetsIndication121923_text_638370', 'drugName': 'Lidocaine', 'tradeNames_list': "['Alphacaine', 'Anestacon', 'Dentipatch', 'Lidocaine', 'LidodermLignocaine Hcl', 'Lignostab', 'Lmx 4', 'Oraqix', 'Vagisil', 'XylocaineXylodase', 'Xylotox', 'Ztlido']", 'syns_list': "['ALGRX 3268', 'ALGRX-3268', 'Anestacon'... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.707 | Q6 | What genes does Oxcarbazepine target when it's used to treat epilepsy? | When used to treat epilepsy, the drug Oxcarbazepine targets the genes SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%oxcarbazepine%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_633093', 'drugName': 'Oxcarbazepine', 'tradeNames_list': "['Oxcarbazepine', 'Oxtellar xr', 'Trileptal']", 'syns_list': "['GP-47680', 'KIN-493', 'NSC-758693', 'Oxcarbamazepine', 'OxcarbazepineSPN-804']", 'target': 'ENSG00000007314', 'approvedSymbol': 'SCN4A', 'approvedName': '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1979 | Q6 | What genes does Ponatinib Hydrochloride target when it's used to treat chronic myelogenous leukemia? | When used to treat chronic myelogenous leukemia, the drug Ponatinib Hydrochloride targets the genes ABL1 and BCR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ponatinib hydrochloride%" OR LOWER(tradeNames_lis... | [{'UUID': 'DrugTargetsIndication121923_text_749871', 'drugName': 'Ponatinib Hydrochloride', 'tradeNames_list': "['Iclusig']", 'syns_list': "['AP-24534 HCL', 'AP24534 HCL', 'Ponatinib hydrochloride']", 'target': 'ENSG00000186716', 'approvedSymbol': 'BCR', 'approvedName': 'BCR activator of RhoGEF and GTPase', 'mesh_headi... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1189 | Q6 | What genes does Glucagon target when it's used to treat hyperinsulinemic hypoglycemia? | Glucagon has not been approved by the FDA as a treatment for hyperinsulinemic hypoglycemia, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is GCGR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%glucagon%" OR LOWER(tradeNames_list) LIKE "%gluca... | [{'UUID': 'DrugTargetsIndication121923_text_968329', 'drugName': 'Glucagon', 'tradeNames_list': "['Baqsimi', 'Glucagen Hypokit', 'Glucagon', 'Glucagon Emergency KitGvoke hypopen', 'Gvoke pfs']", 'syns_list': "['Glucagon', 'Glucagon recombinant']", 'target': 'ENSG00000215644', 'approvedSymbol': 'GCGR', 'approvedName': '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.345 | Q6 | What genes does Cabazitaxel target when it's used to treat neoplasm? | When used to treat neoplasm, the drug Cabazitaxel targets the genes TUBB4B, TUBB1, TUBA3C, TUBA4A, TUBB3, TUBA1A, TUBB4A, TUBB8, TUBB, TUBA1B, TUBA1C, TUBA3E, TUBB2A, TUBB2B, and TUBB6. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%cabazitaxel%" OR LOWER(tradeNames_list) LIKE "%ca... | [{'UUID': 'DrugTargetsIndication121923_text_67929', 'drugName': 'Cabazitaxel', 'tradeNames_list': "['Jevtana', 'Jevtana kit']", 'syns_list': "['Cabazitaxel', 'Cabazitaxel acetonate', 'Jevtana', 'NSC-761432', 'TXD 258TXD-258', 'XRP 6258', 'XRP-6258']", 'target': 'ENSG00000188229', 'approvedSymbol': 'TUBB4B', 'approvedNa... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.636 | Q6 | What genes does Osimertinib target when it's used to treat cancer? | When used to treat cancer, the drug Osimertinib targets the gene EGFR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%osimertinib%" OR LOWER(tradeNames_list) LIKE "%os... | [{'UUID': 'DrugTargetsIndication121923_text_217363', 'drugName': 'Osimertinib', 'tradeNames_list': "['Tagrisso']", 'syns_list': "['AZD-9291', 'AZD-9291 FREE BASE', 'AZD9291', 'Azd-9291', 'MereletinibOsimertinib']", 'target': 'ENSG00000146648', 'approvedSymbol': 'EGFR', 'approvedName': 'epidermal growth factor receptor'... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.150 | Q6 | What genes does Dexamethasone target when it's used to treat gout? | When used to treat gout, the drug Dexamethasone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dexamethasone%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_230330', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1197 | Q6 | What genes does Cyclobenzaprine Hydrochloride target when it's used to treat Myalgia? | When used to treat Myalgia, the drug Cyclobenzaprine Hydrochloride targets the genes HTR2C and HTR2A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%cyclobenzaprine hydrochloride%" OR LOWER(tradeNam... | [{'UUID': 'DrugTargetsIndication121923_text_151277', 'drugName': 'Cyclobenzaprine Hydrochloride', 'tradeNames_list': "['Amrix', 'Cyclobenzaprine hydrochloride', 'Flexeril']", 'syns_list': "['Cyclobenzaprine hcl', 'Cyclobenzaprine hydrochloride', 'MK-130MK-130 HYDROCHLORIDE', 'MK-130 [AS THE BASE]', 'NSC-169900', 'NSC-1... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.365 | Q6 | What genes does Fluticasone Propionate target when it's used to treat chronic obstructive pulmonary disease? | When used to treat chronic obstructive pulmonary disease, the drug Fluticasone Propionate targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fluticasone propionate%" OR LOWER(tradeNames_list... | [{'UUID': 'DrugTargetsIndication121923_text_232529', 'drugName': 'Fluticasone Propionate', 'tradeNames_list': "['Aerivio spiromax', 'Airflusal forspiro', 'Armonair digihalerArmonair respiclick', 'Cutivate', 'Flixonase', 'Flixotide', 'FlonaseFlonase allergy relief', 'Flovent', 'Flovent diskus 100Flovent diskus 250', 'Fl... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.86 | Q6 | What genes does Pralatrexate target when it's used to treat neoplasm? | When used to treat neoplasm, the drug Pralatrexate targets the gene DHFR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%pralatrexate%" OR LOWER(tradeNames_list) LIKE "%p... | [{'UUID': 'DrugTargetsIndication121923_text_1072438', 'drugName': 'Pralatrexate', 'tradeNames_list': "['Folotyn']", 'syns_list': "['NSC-754230', 'PDX', 'Pralatrexate']", 'target': 'ENSG00000228716', 'approvedSymbol': 'DHFR', 'approvedName': 'dihydrofolate reductase', 'mesh_heading': 'Neoplasms', 'efo_term': 'cancer', '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.49 | Q6 | What genes does Everolimus target when it's used to treat astrocytoma? | When used to treat astrocytoma, the drug Everolimus targets the gene FKBP1A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%everolimus%" OR LOWER(tradeNames_list) LIKE "%eve... | [{'UUID': 'DrugTargetsIndication121923_text_1088075', 'drugName': 'Everolimus', 'tradeNames_list': "['Afinitor', 'Afinitor disperz', 'Certican', 'Votubia', 'Zortress']", 'syns_list': "['40-o-(2-hydroxyethyl)-rapamycin', 'Everolimus', 'RAD 666', 'RAD-001RAD-666', 'RAD001', 'SDZ-RAD', 'Sdz rad']", 'target': 'ENSG00000088... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.474 | Q6 | What genes does Lurasidone target when it's used to treat psychosis? | When used to treat psychosis, the drug Lurasidone targets the genes DRD2 and HTR2A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lurasidone%" OR LOWER(tradeNames_list) LIKE "%lur... | [{'UUID': 'DrugTargetsIndication121923_text_198424', 'drugName': 'Lurasidone', 'tradeNames_list': "['Latuda']", 'syns_list': "['Lurasidone']", 'target': 'ENSG00000149295', 'approvedSymbol': 'DRD2', 'approvedName': 'dopamine receptor D2', 'mesh_heading': 'Psychotic Disorders', 'efo_term': 'psychosis', 'yearOfFirstApprov... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.158 | Q6 | What genes does Methotrexate target when it's used to treat Lymphoma, AIDS-Related? | Methotrexate has not been approved by the FDA as a treatment for Lymphoma, AIDS-Related, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is DHFR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%methotrexate%" OR LOWER(tradeNames_list) LIKE "%m... | [{'UUID': 'DrugTargetsIndication121923_text_1057483', 'drugName': 'Methotrexate', 'tradeNames_list': "['Amethopterin', 'Ebetrex', 'Emtexate high-pot', 'Emtexate pf', 'FolexMaxtrex', 'Methotrexate', 'Metoject', 'Mexate', 'Otrexup', 'Otrexup pfsRasuvo', 'Reditrex', 'Rheumatrex', 'Trexall', 'Zlatal']", 'syns_list': "['(r)... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.764 | Q6 | What genes does Vandetanib target when it's used to treat thyroid cancer? | When used to treat thyroid cancer, the drug Vandetanib targets the genes EGFR, ERBB3, KDR, SRC, TEK, ERBB2, FLT1, FLT4, EPHA2, RET, ERBB4, EPHB4, PTK6, EPHB2, EPHA5, EPHA4, EPHA8, EPHA6, EPHA7, EPHB3, EPHA3, EPHB1, EPHA1, EPHB6, and EPHA10. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%vandetanib%" OR LOWER(tradeNames_list) LIKE "%van... | [{'UUID': 'DrugTargetsIndication121923_text_210188', 'drugName': 'Vandetanib', 'tradeNames_list': "['Caprelsa', 'Zactima']", 'syns_list': "['GNF-PF-2188', 'NSC-744325', 'NSC-760766', 'Vandetanib', 'ZD-64', 'ZD-6474ZD6474']", 'target': 'ENSG00000146648', 'approvedSymbol': 'EGFR', 'approvedName': 'epidermal growth factor... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1027 | Q6 | What genes does Fingolimod target when it's used to treat Renal insufficiency? | Fingolimod has not been approved by the FDA as a treatment for Renal insufficiency, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are S1PR5, S1PR2, S1PR4, S1PR3, and S1PR1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fingolimod%" OR LOWER(tradeNames_list) LIKE "%fin... | [{'UUID': 'DrugTargetsIndication121923_text_1035389', 'drugName': 'Fingolimod', 'tradeNames_list': "['Gilenya']", 'syns_list': "['FTY-720', 'Fingolimod']", 'target': 'ENSG00000180739', 'approvedSymbol': 'S1PR5', 'approvedName': 'sphingosine-1-phosphate receptor 5', 'mesh_heading': 'Renal Insufficiency', 'efo_term': 'Re... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1200 | Q6 | What genes does Topotecan Hydrochloride target when it's used to treat carcinoma? | When used to treat carcinoma, the drug Topotecan Hydrochloride targets the gene TOP1MT. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%topotecan hydrochloride%" OR LOWER(tradeNames_lis... | [{'UUID': 'DrugTargetsIndication121923_text_1193650', 'drugName': 'Topotecan Hydrochloride', 'tradeNames_list': "['Hycamptin', 'Hycamtin', 'Topotecan', 'Topotecan hydrochloride']", 'syns_list': "['Evotopin', 'NSC-759263', 'Nogitecan hydrochloride', 'SK&F S-104864-ASK&F-S-104864A', 'SK-S-104864-A', 'Topotecan (as hydroc... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1404 | Q6 | What genes does Beclomethasone Dipropionate target when it's used to treat Nasal congestion? | When used to treat Nasal congestion, the drug Beclomethasone Dipropionate targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%beclomethasone dipropionate%" OR LOWER(tradeNames... | [{'UUID': 'DrugTargetsIndication121923_text_221041', 'drugName': 'Beclomethasone Dipropionate', 'tradeNames_list': "['Aerobec 100', 'Aerobec 50', 'Aerobec fte 250', 'Asmabec clickhalerAsmabec spacehaler', 'Beclazone 100', 'Beclazone 100 e-breatheBeclazone 200', 'Beclazone 250', 'Beclazone 250 e-breathe', 'Beclazone 50B... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1202 | Q6 | What genes does Telmisartan target when it's used to treat diabetes mellitus? | When used to treat diabetes mellitus, the drug Telmisartan targets the gene AGTR1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%telmisartan%" OR LOWER(tradeNames_list) LIKE "%te... | [{'UUID': 'DrugTargetsIndication121923_text_1072709', 'drugName': 'Telmisartan', 'tradeNames_list': "['Micardis', 'Telmisartan', 'Tolura']", 'syns_list': "['BIBR 277 SE', 'BIBR-277', 'BIBR-277 SE', 'BIBR-277-SE', 'BIBR-277SEC09CA07', 'Kinzalmono', 'Pritor', 'Semintra', 'TelmisartanTelmisartan actavis', 'Telmisartan tev... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1631 | Q6 | What genes does Zoledronic Acid target when it's used to treat bone disease? | When used to treat bone disease, the drug Zoledronic Acid targets the gene FDPS. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%zoledronic acid%" OR LOWER(tradeNames_list) LIKE ... | [{'UUID': 'DrugTargetsIndication121923_text_1099769', 'drugName': 'Zoledronic Acid', 'tradeNames_list': "['Aclasta', 'Reclast', 'Zerlinda', 'Zoledronic acid', 'Zometa']", 'syns_list': "['AK-156', 'Anhydrous zoledronic acid', 'CGP 42446', 'CGP-42446', 'CGP-42446ANSC-721517', 'Zoladrona acid mylan', 'Zoledronate', 'Zoled... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.506 | Q6 | What genes does Paclitaxel target when it's used to treat cervical adenocarcinoma? | Paclitaxel has not been approved by the FDA as a treatment for cervical adenocarcinoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are TUBB4B, TUBB1, TUBA3C, TUBA4A, TUBB3, TUBA1A, TUBB4A, TUBB8, TUBB, TUBA1B, TUBA1C, TUBA3E, TUBB2A, TUBB2B, and TUBB6. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%paclitaxel%" OR LOWER(tradeNames_list) LIKE "%pac... | [{'UUID': 'DrugTargetsIndication121923_text_871', 'drugName': 'Paclitaxel', 'tradeNames_list': "['Abraxane', 'Pacitaxel', 'Paclitaxel', 'Paxene', 'Taxol', 'Taxol 100']", 'syns_list': "['(-)-paclitaxel', 'ABI-007', 'ABI-007 COMPONENT PACLITAXEL', 'BMS 181339-01BMS-181339-01', 'Capxol', 'Cyclopax', 'DHP 107', 'DHP-107', ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1670 | Q6 | What genes does Lenvatinib target when it's used to treat non-small cell lung carcinoma? | Lenvatinib has not been approved by the FDA as a treatment for non-small cell lung carcinoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are KDR, FLT1, and FLT4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lenvatinib%" OR LOWER(tradeNames_list) LIKE "%len... | [{'UUID': 'DrugTargetsIndication121923_text_691816', 'drugName': 'Lenvatinib', 'tradeNames_list': "['Kisplyx', 'Lenvima']", 'syns_list': "['E-7080', 'ER-203492-00', 'Lenvatinib']", 'target': 'ENSG00000102755', 'approvedSymbol': 'FLT1', 'approvedName': 'fms related receptor tyrosine kinase 1', 'mesh_heading': 'Carcinoma... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.182 | Q6 | What genes does Cabozantinib S-Malate target when it's used to treat renal cell carcinoma? | When used to treat renal cell carcinoma, the drug Cabozantinib S-Malate targets the genes KDR and MET. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%cabozantinib s-malate%" OR LOWER(tradeNames_list)... | [{'UUID': 'DrugTargetsIndication121923_text_669605', 'drugName': 'Cabozantinib S-Malate', 'tradeNames_list': "['Cabometyx', 'Cometriq']", 'syns_list': "['BMS-907351', 'Cabozantinib malate', 'Cabozantinib s-malate', 'XL-184XL184']", 'target': 'ENSG00000128052', 'approvedSymbol': 'KDR', 'approvedName': 'kinase insert dom... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1419 | Q6 | What genes does Dexamethasone target when it's used to treat trichinosis? | When used to treat trichinosis, the drug Dexamethasone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dexamethasone%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_227777', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1014 | Q6 | What genes does Topotecan target when it's used to treat neoplasm? | When used to treat neoplasm, the drug Topotecan targets the gene TOP1MT. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%topotecan%" OR LOWER(tradeNames_list) LIKE "%topo... | [{'UUID': 'DrugTargetsIndication121923_text_1193661', 'drugName': 'Topotecan', 'tradeNames_list': "['Hycamtin', 'Potactasol']", 'syns_list': "['Ff-10850 (liposomal topotecan)', 'Hycamptamine', 'Hycamptin', 'HycamtinNSC-609699', 'NSC-641007', 'Nogitecan', 'SKF-104864', 'Topotecan']", 'target': 'ENSG00000184428', 'approv... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1978 | Q6 | What genes does Fenofibric Acid target when it's used to treat Hypercholesterolemia? | When used to treat Hypercholesterolemia, the drug Fenofibric Acid targets the gene PPARA. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fenofibric acid%" OR LOWER(tradeNames_list) LIKE ... | [{'UUID': 'DrugTargetsIndication121923_text_243842', 'drugName': 'Fenofibric Acid', 'tradeNames_list': "['Fenocor-67', 'Fenogal', 'Fibricor', 'Lipanthyl', 'Lipofen', 'LofibraSupralip', 'Trilipix']", 'syns_list': "['Fenofibrate free acid', 'Fenofibrate related compound bFenofibric acid', 'LF-153', 'NSC-281318', 'Proceto... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.864 | Q6 | What genes does Rosuvastatin Calcium target when it's used to treat familial hypercholesterolemia? | When used to treat familial hypercholesterolemia, the drug Rosuvastatin Calcium targets the gene HMGCR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%rosuvastatin calcium%" OR LOWER(tradeNames_list) ... | [{'UUID': 'DrugTargetsIndication121923_text_1104218', 'drugName': 'Rosuvastatin Calcium', 'tradeNames_list': "['Crestor', 'Ezallor', 'Ezallor sprinkle', 'Rosuvastatin calcium']", 'syns_list': "['Fortius', 'NSC-747274', 'NSC-758930', 'Rostar', 'Rosuvastatin (as calcium)Rosuvastatin calcium', 'Rosuvastatin calcium saltRo... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1620 | Q6 | What genes does Naproxen target when it's used to treat osteoarthritis? | When used to treat osteoarthritis, the drug Naproxen targets the genes PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%naproxen%" OR LOWER(tradeNames_list) LIKE "%napro... | [{'UUID': 'DrugTargetsIndication121923_text_839045', 'drugName': 'Naproxen', 'tradeNames_list': "['Aleve', 'Anaprox', 'Arthrosin 250', 'Arthrosin 250 ec', 'Arthrosin 500Arthrosin 500 ec', 'Condrotec', 'Ec-naprosyn', 'Equiproxen', 'Feminax ultraGrenoxal', 'Kenosyn', 'Laraflex', 'Napratec op', 'Naprosyn', 'Naprosyn 375Na... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.534 | Q6 | What genes does Naloxone Hydrochloride target when it's used to treat unipolar depression? | When used to treat unipolar depression, the drug Naloxone Hydrochloride targets the genes OPRM1, OPRK1, and OPRD1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%naloxone hydrochloride%" OR LOWER(tradeNames_list... | [{'UUID': 'DrugTargetsIndication121923_text_789393', 'drugName': 'Naloxone Hydrochloride', 'tradeNames_list': "['Evzio', 'Evzio (autoinjector)', 'Kloxxado', 'Nalone', 'NaloxoneNaloxone hydrochloride', 'Naloxone hydrochloride (autoinjector)', 'NarcanNarcan neonatal', 'Narconil', 'Prenoxad', 'Zimhi']", 'syns_list': "['An... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.350 | Q6 | What genes does Dexamethasone target when it's used to treat Aplastic anemia? | When used to treat Aplastic anemia, the drug Dexamethasone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dexamethasone%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_227740', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1389 | Q6 | What genes does Isotretinoin target when it's used to treat glioblastoma multiforme? | Isotretinoin has not been approved by the FDA as a treatment for glioblastoma multiforme, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are RARG, RARB, and RARA. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%isotretinoin%" OR LOWER(tradeNames_list) LIKE "%i... | [{'UUID': 'DrugTargetsIndication121923_text_1053992', 'drugName': 'Isotretinoin', 'tradeNames_list': "['Absorica', 'Absorica ld', 'Accutane', 'Amnesteem', 'Claravis', 'IsotrexMyorisan', 'Roaccutane', 'Sotret', 'Zenatane']", 'syns_list': "['13 Cis-Retinoic Acid', '13-cis-retinoic acid', 'Isotretinoin', 'NSC-758156PAT-00... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1961 | Q6 | What genes does Dexamethasone target when it's used to treat eye inflammation? | When used to treat eye inflammation, the drug Dexamethasone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dexamethasone%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_227770', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1301 | Q6 | What genes does Eribulin Mesylate target when it's used to treat breast cancer? | When used to treat breast cancer, the drug Eribulin Mesylate targets the genes TUBB4B, TUBB1, TUBA3C, TUBA4A, TUBB3, TUBA1A, TUBB4A, TUBB8, TUBB, TUBA1B, TUBA1C, TUBA3E, TUBB2A, TUBB2B, and TUBB6. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%eribulin mesylate%" OR LOWER(tradeNames_list) LIK... | [{'UUID': 'DrugTargetsIndication121923_text_147349', 'drugName': 'Eribulin Mesylate', 'tradeNames_list': "['Halaven']", 'syns_list': "['E-7389', 'E7389', 'Eribulin (as mesylate)', 'Eribulin mesilateEribulin mesylate', 'Eribulin monomethanesulfonate', 'Halaven']", 'target': 'ENSG00000196230', 'approvedSymbol': 'TUBB', '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1973 | Q6 | What genes does Vismodegib target when it's used to treat neoplasm? | When used to treat neoplasm, the drug Vismodegib targets the gene SMO. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%vismodegib%" OR LOWER(tradeNames_list) LIKE "%vis... | [{'UUID': 'DrugTargetsIndication121923_text_1072558', 'drugName': 'Vismodegib', 'tradeNames_list': "['Erivedge']", 'syns_list': "['GDC-0449', 'NSC-747691', 'NSC-755986', 'Vismodegib']", 'target': 'ENSG00000128602', 'approvedSymbol': 'SMO', 'approvedName': 'smoothened, frizzled class receptor', 'mesh_heading': 'Neoplasm... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1980 | Q6 | What genes does Clozapine target when it's used to treat bipolar disorder? | Clozapine has not been approved by the FDA as a treatment for bipolar disorder, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are DRD2 and HTR2A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%clozapine%" OR LOWER(tradeNames_list) LIKE "%cloz... | [{'UUID': 'DrugTargetsIndication121923_text_157979', 'drugName': 'Clozapine', 'tradeNames_list': "['Clozapine', 'Clozaril', 'Fazaclo', 'Fazaclo odt', 'Versacloz', 'Zaponex']", 'syns_list': "['Clozapine', 'Clozapine (caraco)', 'Clozapine (clozaril)Clozapine (fazaclo)', 'Clozapine (ivax)', 'Clozapine (mylan)Clozapine (te... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.608 | Q6 | What genes does Prednisolone Acetate target when it's used to treat multiple sclerosis? | When used to treat multiple sclerosis, the drug Prednisolone Acetate targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%prednisolone acetate%" OR LOWER(tradeNames_list) ... | [{'UUID': 'DrugTargetsIndication121923_text_243765', 'drugName': 'Prednisolone Acetate', 'tradeNames_list': "['Econopred', 'Flo-pred', 'Meticortelone', 'Omnipred', 'Pred forte', 'Pred ftePred mild', 'Prednisolone acetate', 'Sterane', 'Ultracortenol']", 'syns_list': "['NSC-10966', 'Prednisolone 21-acetate', 'Prednisolon... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1050 | Q6 | What genes does Fluocinolone Acetonide target when it's used to treat atopic eczema? | When used to treat atopic eczema, the drug Fluocinolone Acetonide targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fluocinolone acetonide%" OR LOWER(tradeNames_list... | [{'UUID': 'DrugTargetsIndication121923_text_242233', 'drugName': 'Fluocinolone Acetonide', 'tradeNames_list': "['Capex', 'Derma-smoothe/fs', 'Dermotic', 'Fluocet', 'Fluocinolone acetonideFluonid', 'Fluotrex', 'Fs shampoo', 'Iluvien', 'Retisert', 'SynalarSynalar fte', 'Synalar-c', 'Synalar-hp', 'Synalar-n', 'Synandone',... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.246 | Q6 | What genes does Eribulin target when it's used to treat cancer? | When used to treat cancer, the drug Eribulin targets the genes TUBB4B, TUBB1, TUBA3C, TUBA4A, TUBB3, TUBA1A, TUBB4A, TUBB8, TUBB, TUBA1B, TUBA1C, TUBA3E, TUBB2A, TUBB2B, and TUBB6. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%eribulin%" OR LOWER(tradeNames_list) LIKE "%eribu... | [{'UUID': 'DrugTargetsIndication121923_text_147469', 'drugName': 'Eribulin Mesylate', 'tradeNames_list': "['Halaven']", 'syns_list': "['E-7389', 'E7389', 'Eribulin (as mesylate)', 'Eribulin mesilateEribulin mesylate', 'Eribulin monomethanesulfonate', 'Halaven']", 'target': 'ENSG00000123416', 'approvedSymbol': 'TUBA1B',... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1681 | Q6 | What genes does Bupivacaine target when it's used to treat liver disease? | Bupivacaine has not been approved by the FDA as a treatment for liver disease, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is SCN4A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%bupivacaine%" OR LOWER(tradeNames_list) LIKE "%bu... | [{'UUID': 'DrugTargetsIndication121923_text_663112', 'drugName': 'Bupivacaine', 'tradeNames_list': "['Anekain', 'Exparel', 'Marcaine', 'Posimir', 'Sensorcaine']", 'syns_list': "['Bucaine', 'Bupivacaine', 'Bupivacaine liposome', 'LIQ-865', 'LIQ865Liposomal bupivacaine', 'MarcaineRopivacaine hydrochloride impurity, bupiv... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1799 | Q6 | What genes does Regadenoson target when it's used to treat cardiovascular disease? | When used to treat cardiovascular disease, the drug Regadenoson targets the gene ADORA2A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%regadenoson%" OR LOWER(tradeNames_list) LIKE "%re... | [{'UUID': 'DrugTargetsIndication121923_text_695324', 'drugName': 'Regadenoson', 'tradeNames_list': "['Lexiscan']", 'syns_list': "['CVT-3146', 'Rapiscan', 'Regadenoson', 'Regadenoson hydrate']", 'target': 'ENSG00000128271', 'approvedSymbol': 'ADORA2A', 'approvedName': 'adenosine A2a receptor', 'mesh_heading': 'Cardiovas... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1717 | Q6 | What genes does Clonidine target when it's used to treat neuropathic pain? | When used to treat neuropathic pain, the drug Clonidine targets the genes ADRA2A, ADRA2C, and ADRA2B. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%clonidine%" OR LOWER(tradeNames_list) LIKE "%clon... | [{'UUID': 'DrugTargetsIndication121923_text_1033832', 'drugName': 'Clonidine', 'tradeNames_list': "['Catapres', 'Catapres-tts-1', 'Catapres-tts-2', 'Catapres-tts-3', 'ClonidineNexiclon xr']", 'syns_list': "['Catapres', 'Catarpres-tts', 'Clonidine', 'Clonidine extended releaseClorpres', 'Combipres', 'Duraclon', 'ST-155-... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.316 | Q6 | What genes does Ruxolitinib Phosphate target when it's used to treat polycythemia vera? | When used to treat polycythemia vera, the drug Ruxolitinib Phosphate targets the genes JAK1 and JAK2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ruxolitinib phosphate%" OR LOWER(tradeNames_list)... | [{'UUID': 'DrugTargetsIndication121923_text_843692', 'drugName': 'Ruxolitinib Phosphate', 'tradeNames_list': "['Jakafi', 'Opzelura']", 'syns_list': "['INCB-018424 PHOSPHATE', 'INCB-018424 SALT', 'INCB-18424 PHOSPHATEINCB018424 PHOSPHATE', 'INCB018424 SALT', 'OpzeluraRuxolitinib (as phosphate)', 'Ruxolitinib monophospha... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.441 | Q6 | What genes does Ospemifene target when it's used to treat Dyspareunia? | When used to treat Dyspareunia, the drug Ospemifene targets the genes ESR1 and ESR2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ospemifene%" OR LOWER(tradeNames_list) LIKE "%osp... | [{'UUID': 'DrugTargetsIndication121923_text_823746', 'drugName': 'Ospemifene', 'tradeNames_list': "['Osphena', 'Senshio']", 'syns_list': "['(deaminohydroxy) toremifene', 'FC-1271', 'FC-1271A', 'OspemifeneTore iii']", 'target': 'ENSG00000091831', 'approvedSymbol': 'ESR1', 'approvedName': 'estrogen receptor 1', 'mesh_hea... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1899 | Q6 | What genes does Milnacipran Hydrochloride target when it's used to treat fibromyalgia? | When used to treat fibromyalgia, the drug Milnacipran Hydrochloride targets the genes SLC6A4 and SLC6A2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%milnacipran hydrochloride%" OR LOWER(tradeNames_l... | [{'UUID': 'DrugTargetsIndication121923_text_206850', 'drugName': 'Milnacipran Hydrochloride', 'tradeNames_list': "['Dalcipran', 'Ixel', 'Milnacipran hydrochloride', 'Savella', 'Toledomin']", 'syns_list': "['Milnacipran hcl', 'Milnacipran hydrochloride', 'NSC-759806']", 'target': 'ENSG00000108576', 'approvedSymbol': 'SL... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1637 | Q6 | What genes does Triamcinolone Acetonide target when it's used to treat frozen shoulder? | When used to treat frozen shoulder, the drug Triamcinolone Acetonide targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%triamcinolone acetonide%" OR LOWER(tradeNames_lis... | [{'UUID': 'DrugTargetsIndication121923_text_222206', 'drugName': 'Triamcinolone Acetonide', 'tradeNames_list': "['Adcortyl', 'Adcortyl in orabase', 'Allernaze', 'Aristocort', 'Aristocort aAristogel', 'Audicort', 'Aureocort', 'Azmacort', 'Flutex', 'Gppe ear dps capGppe ear oint', 'Kenacort', 'Kenalog', 'Kenalog in oraba... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.312 | Q6 | What genes does Lidocaine target when it's used to treat common cold? | Lidocaine has not been approved by the FDA as a treatment for common cold, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lidocaine%" OR LOWER(tradeNames_list) LIKE "%lido... | [{'UUID': 'DrugTargetsIndication121923_text_637987', 'drugName': 'Lidocaine', 'tradeNames_list': "['Alphacaine', 'Anestacon', 'Dentipatch', 'Lidocaine', 'LidodermLignocaine Hcl', 'Lignostab', 'Lmx 4', 'Oraqix', 'Vagisil', 'XylocaineXylodase', 'Xylotox', 'Ztlido']", 'syns_list': "['ALGRX 3268', 'ALGRX-3268', 'Anestacon'... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.436 | Q6 | What genes does Cobimetinib target when it's used to treat ovarian cancer? | Cobimetinib has not been approved by the FDA as a treatment for ovarian cancer, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are MAP2K2 and MAP2K1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%cobimetinib%" OR LOWER(tradeNames_list) LIKE "%co... | [{'UUID': 'DrugTargetsIndication121923_text_927303', 'drugName': 'Cobimetinib', 'tradeNames_list': "['Cotellic']", 'syns_list': "['Cobimetinib', 'GDC-0973', 'Gdc 0623', 'Gdc 0973', 'Gdc-0623', 'RG 7420RG-7420', 'RG7420', 'Rg-7420', 'Rg-7421', 'XL-518', 'Xl 518', 'Xl518']", 'target': 'ENSG00000126934', 'approvedSymbol':... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.667 | Q6 | What genes does Inotersen Sodium target when it's used to treat familial amyloid neuropathy? | When used to treat familial amyloid neuropathy, the drug Inotersen Sodium targets the gene TTR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%inotersen sodium%" OR LOWER(tradeNames_list) LIKE... | [{'UUID': 'DrugTargetsIndication121923_text_1097657', 'drugName': 'Inotersen Sodium', 'tradeNames_list': "['Tegsedi']", 'syns_list': "['Inotersen sodium']", 'target': 'ENSG00000118271', 'approvedSymbol': 'TTR', 'approvedName': 'transthyretin', 'mesh_heading': 'Amyloid Neuropathies, Familial', 'efo_term': 'familial amyl... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.376 | Q6 | What genes does Treprostinil target when it's used to treat ischemia? | Treprostinil has not been approved by the FDA as a treatment for ischemia, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is PTGIR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%treprostinil%" OR LOWER(tradeNames_list) LIKE "%t... | [{'UUID': 'DrugTargetsIndication121923_text_245002', 'drugName': 'Treprostinil', 'tradeNames_list': "['Remodulin', 'Tyvaso', 'Tyvaso dpi']", 'syns_list': "['15-AU-81', '15AU81', 'L-606', 'LRX -15', 'LRX-15', 'Rumodolin', 'TreprostinilTresprostinil', 'UT-15', 'Uniprost']", 'target': 'ENSG00000160013', 'approvedSymbol': ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.572 | Q6 | What genes does Everolimus target when it's used to treat pancreatic neuroendocrine tumor? | When used to treat pancreatic neuroendocrine tumor, the drug Everolimus targets the gene FKBP1A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%everolimus%" OR LOWER(tradeNames_list) LIKE "%eve... | [{'UUID': 'DrugTargetsIndication121923_text_1085638', 'drugName': 'Everolimus', 'tradeNames_list': "['Afinitor', 'Afinitor disperz', 'Certican', 'Votubia', 'Zortress']", 'syns_list': "['40-o-(2-hydroxyethyl)-rapamycin', 'Everolimus', 'RAD 666', 'RAD-001RAD-666', 'RAD001', 'SDZ-RAD', 'Sdz rad']", 'target': 'ENSG00000088... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1226 | Q6 | What genes does Riluzole target when it's used to treat spinal muscular atrophy? | Riluzole has not been approved by the FDA as a treatment for spinal muscular atrophy, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%riluzole%" OR LOWER(tradeNames_list) LIKE "%riluz... | [{'UUID': 'DrugTargetsIndication121923_text_636326', 'drugName': 'Riluzole', 'tradeNames_list': "['Exservan', 'Rilutek', 'Riluzole', 'Teglutik', 'Tiglutik kit']", 'syns_list': "['BHV-0223', 'NSC-753433', 'NSC-759823', 'RP 54274', 'RP-54274', 'RiluzoleTiglutik']", 'target': 'ENSG00000183873', 'approvedSymbol': 'SCN5A', ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.184 | Q6 | What genes does Avacopan target when it's used to treat anti-neutrophil antibody associated vasculitis? | When used to treat anti-neutrophil antibody associated vasculitis, the drug Avacopan targets the gene C5AR1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%avacopan%" OR LOWER(tradeNames_list) LIKE "%avaco... | [{'UUID': 'DrugTargetsIndication121923_text_1191848', 'drugName': 'Avacopan', 'tradeNames_list': "['Tavneos']", 'syns_list': "['Avacopan', 'CCX-168', 'CCX168', 'Ccx168']", 'target': 'ENSG00000197405', 'approvedSymbol': 'C5AR1', 'approvedName': 'complement C5a receptor 1', 'mesh_heading': 'Anti-Neutrophil Cytoplasmic An... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1115 | Q6 | What genes does Belinostat target when it's used to treat neoplasm? | When used to treat neoplasm, the drug Belinostat targets the genes HDAC1, HDAC3, HDAC6, HDAC2, HDAC5, HDAC7, HDAC8, HDAC11, HDAC4, HDAC9, and HDAC10. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%belinostat%" OR LOWER(tradeNames_list) LIKE "%bel... | [{'UUID': 'DrugTargetsIndication121923_text_1080211', 'drugName': 'Belinostat', 'tradeNames_list': "['Beleodaq']", 'syns_list': "['Belinostat', 'NSC-726630', 'NSC726630', 'PX-105684', 'PXD-101', 'PXD101']", 'target': 'ENSG00000061273', 'approvedSymbol': 'HDAC7', 'approvedName': 'histone deacetylase 7', 'mesh_heading': ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.628 | Q6 | What genes does Pramipexole Dihydrochloride target when it's used to treat restless legs syndrome? | When used to treat restless legs syndrome, the drug Pramipexole Dihydrochloride targets the genes DRD2, DRD3, and DRD4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%pramipexole dihydrochloride%" OR LOWER(tradeNames... | [{'UUID': 'DrugTargetsIndication121923_text_199728', 'drugName': 'Pramipexole Dihydrochloride', 'tradeNames_list': "['Mirapex', 'Mirapex Extended Release', 'Mirapex erPramipexole dihydrochloride']", 'syns_list': "['Daquiran', 'PNU-98528E', 'Pramipexole accordPramipexole dihydrochloride', 'Pramipexole dihydrochloride an... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1910 | Q6 | What genes does Irinotecan Hydrochloride target when it's used to treat carcinoma? | When used to treat carcinoma, the drug Irinotecan Hydrochloride targets the gene TOP1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%irinotecan hydrochloride%" OR LOWER(tradeNames_li... | [{'UUID': 'DrugTargetsIndication121923_text_942599', 'drugName': 'Irinotecan Hydrochloride', 'tradeNames_list': "['Campto', 'Camptosar', 'Irinotecan hydrochloride', 'Onivyde']", 'syns_list': "['CPT-11', 'DQ-2805', 'Irinotecan hydrochlorideIrinotecan hydrochloride anhydrous', 'Irinotecan hydrochloride hydrateIrinotecan ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1192 | Q6 | What genes does Methotrexate target when it's used to treat adenoma? | When used to treat adenoma, the drug Methotrexate targets the gene DHFR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%methotrexate%" OR LOWER(tradeNames_list) LIKE "%m... | [{'UUID': 'DrugTargetsIndication121923_text_1057583', 'drugName': 'Methotrexate', 'tradeNames_list': "['Amethopterin', 'Ebetrex', 'Emtexate high-pot', 'Emtexate pf', 'FolexMaxtrex', 'Methotrexate', 'Metoject', 'Mexate', 'Otrexup', 'Otrexup pfsRasuvo', 'Reditrex', 'Rheumatrex', 'Trexall', 'Zlatal']", 'syns_list': "['(r)... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.940 | Q6 | What genes does Levetiracetam target when it's used to treat Seizure? | When used to treat Seizure, the drug Levetiracetam targets the genes CACNA1B and SV2A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%levetiracetam%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_915126', 'drugName': 'Levetiracetam', 'tradeNames_list': "['Desitrend', 'Elepsia xr', 'Keppra', 'Keppra xr', 'LevetiracetamLevetiracetam in sodium chloride', 'Matever', 'Spritam']", 'syns_list': "['AGB-101', 'Elepsia', 'Levetiracetam', 'Levetiracetam accordLevetiracetam actav... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1774 | Q6 | What genes does Prednisone target when it's used to treat Thrombocytopenia? | When used to treat Thrombocytopenia, the drug Prednisone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%prednisone%" OR LOWER(tradeNames_list) LIKE "%pre... | [{'UUID': 'DrugTargetsIndication121923_text_218663', 'drugName': 'Prednisone', 'tradeNames_list': "['Cortan', 'Cortancyl', 'Decortisyl', 'Delta-dome', 'Deltasone', 'FernisoneLiquid pred', 'Lodotra', 'Meticorten', 'Orasone', 'Paracort', 'Prednicen-mPrednisone', 'Prednisone intensol', 'Rayos', 'Servisone', 'Sterapred']",... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1842 | Q6 | What genes does Fentanyl target when it's used to treat pain? | When used to treat pain, the drug Fentanyl targets the gene OPRM1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fentanyl%" OR LOWER(tradeNames_list) LIKE "%fenta... | [{'UUID': 'DrugTargetsIndication121923_text_785759', 'drugName': 'Fentanyl', 'tradeNames_list': "['Abstral', 'Actiq', 'Breakyl', 'Duragesic', 'Duragesic-100', 'Duragesic-12Duragesic-25', 'Duragesic-37', 'Duragesic-50', 'Duragesic-75', 'DurogesicDurogesic dtrans', 'Effentora', 'Fencino', 'Fentalis reservoirFentanyl-100'... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1331 | Q6 | What genes does Desmopressin Acetate target when it's used to treat Central diabetes insipidus? | When used to treat Central diabetes insipidus, the drug Desmopressin Acetate targets the genes AVPR2, AVPR1A, and AVPR1B. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%desmopressin acetate%" OR LOWER(tradeNames_list) ... | [{'UUID': 'DrugTargetsIndication121923_text_694450', 'drugName': 'Desmopressin Acetate', 'tradeNames_list': "['Concentraid', 'Ddavp', 'Ddavp (needs no refrigeration)', 'DesmomeltDesmopressin acetate', 'Desmopressin acetate (needs no refrigeration)Desmopressin acetate preservative free', 'Desmospray', 'DesmotabsMinirin'... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.300 | Q6 | What genes does Propranolol Hydrochloride target when it's used to treat stroke? | When used to treat stroke, the drug Propranolol Hydrochloride targets the genes ADRB2 and ADRB1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%propranolol hydrochloride%" OR LOWER(tradeNames_l... | [{'UUID': 'DrugTargetsIndication121923_text_937041', 'drugName': 'Propranolol Hydrochloride', 'tradeNames_list': "['Angilol', 'Apsolol', 'Avlocardyl', 'Bedranol', 'Bedranol s.r.', 'BerkololBeta-prograne mr', 'Betadur cr', 'Cardinol', 'DupromexHalf beta-prograne mr', 'Half propanix la', 'Half propatard laHalf-beprane cr... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1619 | Q6 | What genes does Belinostat target when it's used to treat urothelial carcinoma? | Belinostat has not been approved by the FDA as a treatment for urothelial carcinoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are HDAC1, HDAC3, HDAC6, HDAC2, HDAC5, HDAC7, HDAC8, HDAC11, HDAC4, HDAC9, and HDAC10. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%belinostat%" OR LOWER(tradeNames_list) LIKE "%bel... | [{'UUID': 'DrugTargetsIndication121923_text_1079969', 'drugName': 'Belinostat', 'tradeNames_list': "['Beleodaq']", 'syns_list': "['Belinostat', 'NSC-726630', 'NSC726630', 'PX-105684', 'PXD-101', 'PXD101']", 'target': 'ENSG00000094631', 'approvedSymbol': 'HDAC6', 'approvedName': 'histone deacetylase 6', 'mesh_heading': ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.467 | Q6 | What genes does Inotersen Sodium target when it's used to treat polyneuropathy? | When used to treat polyneuropathy, the drug Inotersen Sodium targets the gene TTR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%inotersen sodium%" OR LOWER(tradeNames_list) LIKE... | [{'UUID': 'DrugTargetsIndication121923_text_1097658', 'drugName': 'Inotersen Sodium', 'tradeNames_list': "['Tegsedi']", 'syns_list': "['Inotersen sodium']", 'target': 'ENSG00000118271', 'approvedSymbol': 'TTR', 'approvedName': 'transthyretin', 'mesh_heading': 'Polyneuropathies', 'efo_term': 'polyneuropathy', 'yearOfFir... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1302 | Q6 | What genes does Omeprazole target when it's used to treat infection? | When used to treat infection, the drug Omeprazole targets the genes ATP4A and ATP4B. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%omeprazole%" OR LOWER(tradeNames_list) LIKE "%ome... | [{'UUID': 'DrugTargetsIndication121923_text_1097966', 'drugName': 'Omeprazole', 'tradeNames_list': "['Antra', 'Losec', 'Losec mups', 'Mezzopram', 'Mopral', 'Omeprazole', 'OmeranPrilosec', 'Zanprol']", 'syns_list': "['H 168/68', 'H-168/68', 'NSC-751450', 'NSC-759192', 'Omeprazole']", 'target': 'ENSG00000105675', 'approv... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1250 | Q6 | What genes does Vorinostat target when it's used to treat verrucous carcinoma? | Vorinostat has not been approved by the FDA as a treatment for verrucous carcinoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are HDAC1, HDAC3, HDAC6, and HDAC2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%vorinostat%" OR LOWER(tradeNames_list) LIKE "%vor... | [{'UUID': 'DrugTargetsIndication121923_text_1077069', 'drugName': 'Vorinostat', 'tradeNames_list': "['Zolinza']", 'syns_list': "['MK-0683', 'MK0683', 'NSC-701852', 'NSC-748799', 'NSC-759852Suberoylanilide hydroxamic acid', 'Vorinostat']", 'target': 'ENSG00000116478', 'approvedSymbol': 'HDAC1', 'approvedName': 'histone ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.383 | Q6 | What genes does Pacritinib Citrate target when it's used to treat polycythemia vera? | When used to treat polycythemia vera, the drug Pacritinib Citrate targets the genes FLT3 and JAK2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%pacritinib citrate%" OR LOWER(tradeNames_list) LI... | [{'UUID': 'DrugTargetsIndication121923_text_933971', 'drugName': 'Pacritinib Citrate', 'tradeNames_list': "['Vonjo']", 'syns_list': "['Pacritinib citrate']", 'target': 'ENSG00000122025', 'approvedSymbol': 'FLT3', 'approvedName': 'fms related receptor tyrosine kinase 3', 'mesh_heading': 'Polycythemia Vera', 'efo_term': ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1768 | Q6 | What genes does Rosuvastatin Calcium target when it's used to treat coronary artery disease? | When used to treat coronary artery disease, the drug Rosuvastatin Calcium targets the gene HMGCR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%rosuvastatin calcium%" OR LOWER(tradeNames_list) ... | [{'UUID': 'DrugTargetsIndication121923_text_1104216', 'drugName': 'Rosuvastatin Calcium', 'tradeNames_list': "['Crestor', 'Ezallor', 'Ezallor sprinkle', 'Rosuvastatin calcium']", 'syns_list': "['Fortius', 'NSC-747274', 'NSC-758930', 'Rostar', 'Rosuvastatin (as calcium)Rosuvastatin calcium', 'Rosuvastatin calcium saltRo... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.108 | Q6 | What genes does Naproxen Sodium target when it's used to treat Back pain? | When used to treat Back pain, the drug Naproxen Sodium targets the genes PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%naproxen sodium%" OR LOWER(tradeNames_list) LIKE ... | [{'UUID': 'DrugTargetsIndication121923_text_838127', 'drugName': 'Naproxen Sodium', 'tradeNames_list': "['Aleve', 'Anaprox', 'Anaprox ds', 'Naprelan', 'Naproxen sodium', 'Synflex']", 'syns_list': "['BAY-117031', 'BAY117031', 'BAYH6689', 'Naproxen sodiumNaproxen sodium anhydrous', 'Naproxen sodium salt', 'RS-3650']", 't... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.