uuid stringlengths 4 8 | template_uuid stringclasses 40
values | question stringlengths 13 193 | answer stringlengths 29 2.2k | benchmark_query stringlengths 133 622 | execution_results stringlengths 2 1.14M | query_type stringclasses 2
values | sql_category stringclasses 26
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|---|---|---|---|---|---|---|---|---|
Q6.129 | Q6 | What genes does Alectinib target when it's used to treat neoplasm? | When used to treat neoplasm, the drug Alectinib targets the genes RET, ALK, and EML4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%alectinib%" OR LOWER(tradeNames_list) LIKE "%alec... | [{'UUID': 'DrugTargetsIndication121923_text_945671', 'drugName': 'Alectinib', 'tradeNames_list': "['Alecensa']", 'syns_list': "['AF-802', 'AF802', 'Alectinib', 'CH-5424802', 'CH5424802', 'RO-5424802RO5424802']", 'target': 'ENSG00000171094', 'approvedSymbol': 'ALK', 'approvedName': 'ALK receptor tyrosine kinase', 'mesh_... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1131 | Q6 | What genes does Dexamethasone target when it's used to treat erythema multiforme? | When used to treat erythema multiforme, the drug Dexamethasone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dexamethasone%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_227786', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.872 | Q6 | What genes does Lidocaine target when it's used to treat Myalgia? | When used to treat Myalgia, the drug Lidocaine targets the genes SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lidocaine%" OR LOWER(tradeNames_list) LIKE "%lido... | [{'UUID': 'DrugTargetsIndication121923_text_641571', 'drugName': 'Lidocaine', 'tradeNames_list': "['Alphacaine', 'Anestacon', 'Dentipatch', 'Lidocaine', 'LidodermLignocaine Hcl', 'Lignostab', 'Lmx 4', 'Oraqix', 'Vagisil', 'XylocaineXylodase', 'Xylotox', 'Ztlido']", 'syns_list': "['ALGRX 3268', 'ALGRX-3268', 'Anestacon'... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.360 | Q6 | What genes does Lisdexamfetamine Dimesylate target when it's used to treat arteriosclerosis disorder? | When used to treat arteriosclerosis disorder, the drug Lisdexamfetamine Dimesylate targets the genes SLC6A2, SLC18A2, and SLC6A3. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lisdexamfetamine dimesylate%" OR LOWER(tradeNames... | [{'UUID': 'DrugTargetsIndication121923_text_419195', 'drugName': 'Lisdexamfetamine Dimesylate', 'tradeNames_list': "['Elvanse', 'Elvanse adult', 'Vyvanse']", 'syns_list': "['Lisdexamfetamine dimesilate', 'Lisdexamfetamine dimesylateLisdexamfetamine dimethanesulfonate', 'Lisdexamfetamine mesilateLisdexamphetamine dimesi... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1617 | Q6 | What genes does Pemetrexed target when it's used to treat sarcoma? | Pemetrexed has not been approved by the FDA as a treatment for sarcoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are TYMS, GART, and DHFR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%pemetrexed%" OR LOWER(tradeNames_list) LIKE "%pem... | [{'UUID': 'DrugTargetsIndication121923_text_918393', 'drugName': 'Pemetrexed Disodium', 'tradeNames_list': "['Alimta']", 'syns_list': "['LY-231514 DISODIUM SALT', 'LY231514 DISODIUM SALT', 'Pemetrexed disodiumPemetrexed disodium heptahydrate', 'Pemetrexed sodium hydratePemetrexed sodium salt']", 'target': 'ENSG00000228... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.689 | Q6 | What genes does Zoledronic Acid target when it's used to treat osteitis deformans? | When used to treat osteitis deformans, the drug Zoledronic Acid targets the gene FDPS. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%zoledronic acid%" OR LOWER(tradeNames_list) LIKE ... | [{'UUID': 'DrugTargetsIndication121923_text_1099719', 'drugName': 'Zoledronic Acid', 'tradeNames_list': "['Aclasta', 'Reclast', 'Zerlinda', 'Zoledronic acid', 'Zometa']", 'syns_list': "['AK-156', 'Anhydrous zoledronic acid', 'CGP 42446', 'CGP-42446', 'CGP-42446ANSC-721517', 'Zoladrona acid mylan', 'Zoledronate', 'Zoled... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1787 | Q6 | What genes does Lumasiran Sodium target when it's used to treat primary hyperoxaluria type 1? | When used to treat primary hyperoxaluria type 1, the drug Lumasiran Sodium targets the gene HAO1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lumasiran sodium%" OR LOWER(tradeNames_list) LIKE... | [{'UUID': 'DrugTargetsIndication121923_text_1041087', 'drugName': 'Lumasiran Sodium', 'tradeNames_list': "['Oxlumo']", 'syns_list': "['Lumasiran sodium']", 'target': 'ENSG00000101323', 'approvedSymbol': 'HAO1', 'approvedName': 'hydroxyacid oxidase 1', 'mesh_heading': 'Hyperoxaluria, Primary', 'efo_term': 'primary hyper... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1467 | Q6 | What genes does Naproxen Sodium target when it's used to treat gout? | When used to treat gout, the drug Naproxen Sodium targets the genes PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%naproxen sodium%" OR LOWER(tradeNames_list) LIKE ... | [{'UUID': 'DrugTargetsIndication121923_text_838134', 'drugName': 'Naproxen Sodium', 'tradeNames_list': "['Aleve', 'Anaprox', 'Anaprox ds', 'Naprelan', 'Naproxen sodium', 'Synflex']", 'syns_list': "['BAY-117031', 'BAY117031', 'BAYH6689', 'Naproxen sodiumNaproxen sodium anhydrous', 'Naproxen sodium salt', 'RS-3650']", 't... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.212 | Q6 | What genes does Brimonidine Tartrate target when it's used to treat rosacea? | When used to treat rosacea, the drug Brimonidine Tartrate targets the genes ADRA2A, ADRA2C, and ADRA2B. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%brimonidine tartrate%" OR LOWER(tradeNames_list) ... | [{'UUID': 'DrugTargetsIndication121923_text_1034129', 'drugName': 'Brimonidine Tartrate', 'tradeNames_list': "['Alphagan', 'Alphagan p', 'Brimonidine tartrate', 'Brymont', 'LumifyMirvaso', 'Qoliana']", 'syns_list': "['AGN 190342-LF', 'AGN-190342-LF', 'AGN-190342LF', 'Brimonidine d-tartrateBrimonidine tartrate', 'Bromox... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.880 | Q6 | What genes does Celecoxib target when it's used to treat peptic ulcer disease? | When used to treat peptic ulcer disease, the drug Celecoxib targets the gene PTGS2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%celecoxib%" OR LOWER(tradeNames_list) LIKE "%cele... | [{'UUID': 'DrugTargetsIndication121923_text_833504', 'drugName': 'Celecoxib', 'tradeNames_list': "['Celebra', 'Celebrex', 'Celecoxib', 'Elyxyb', 'Onsenal']", 'syns_list': "['Celecoxib', 'DFN-15', 'DFN15', 'NSC-719627', 'NSC-758624', 'SC-58635']", 'target': 'ENSG00000073756', 'approvedSymbol': 'PTGS2', 'approvedName': '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.143 | Q6 | What genes does Gabapentin target when it's used to treat psychosis? | Gabapentin has not been approved by the FDA as a treatment for psychosis, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are CACNA1B, CACNA1C, CACNA1S, CACNA1D, CACNA1F, CACNA2D2, CACNA2D1, CACNA1H, CACNA1G, CACNA1I, CACNA1A, CACNA2D3, CACNA2D4, CACNA1E, CACNB4,... | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%gabapentin%" OR LOWER(tradeNames_list) LIKE "%gab... | [{'UUID': 'DrugTargetsIndication121923_text_895003', 'drugName': 'Gabapentin', 'tradeNames_list': "['Gabapentin', 'Gralise', 'Neurontin']", 'syns_list': "['CI-945', 'DM-1796', 'GOE 3450', 'GOE-3450', 'Gabapentin', 'NSC-742194NSC-759254']", 'target': 'ENSG00000148408', 'approvedSymbol': 'CACNA1B', 'approvedName': 'calci... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1439 | Q6 | What genes does Tazarotene target when it's used to treat psoriasis? | When used to treat psoriasis, the drug Tazarotene targets the genes RARG, RARB, and RARA. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%tazarotene%" OR LOWER(tradeNames_list) LIKE "%taz... | [{'UUID': 'DrugTargetsIndication121923_text_1055477', 'drugName': 'Tazarotene', 'tradeNames_list': "['Arazlo', 'Avage', 'Fabior', 'Tazorac', 'Zorac']", 'syns_list': "['AGN 190168', 'AGN-190168', 'Idp-123', 'Tazarotene']", 'target': 'ENSG00000172819', 'approvedSymbol': 'RARG', 'approvedName': 'retinoic acid receptor gam... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1341 | Q6 | What genes does Vorinostat target when it's used to treat neuroblastoma? | Vorinostat has not been approved by the FDA as a treatment for neuroblastoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are HDAC1, HDAC3, HDAC6, and HDAC2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%vorinostat%" OR LOWER(tradeNames_list) LIKE "%vor... | [{'UUID': 'DrugTargetsIndication121923_text_1077095', 'drugName': 'Vorinostat', 'tradeNames_list': "['Zolinza']", 'syns_list': "['MK-0683', 'MK0683', 'NSC-701852', 'NSC-748799', 'NSC-759852Suberoylanilide hydroxamic acid', 'Vorinostat']", 'target': 'ENSG00000116478', 'approvedSymbol': 'HDAC1', 'approvedName': 'histone ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1786 | Q6 | What genes does Tramadol Hydrochloride target when it's used to treat drug dependence? | When used to treat drug dependence, the drug Tramadol Hydrochloride targets the gene OPRM1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%tramadol hydrochloride%" OR LOWER(tradeNames_list... | [{'UUID': 'DrugTargetsIndication121923_text_766780', 'drugName': 'Tramadol Hydrochloride', 'tradeNames_list': "['Aceon', 'Conzip', 'Dromadol sr', 'Dromadol xl', 'Invodol sr', 'Larapam srMabron', 'Maneo', 'Marol', 'Maxitram sr', 'Nobligan ret', 'Oldaram', 'QdoloRybix odt', 'Ryzolt', 'Tilodol sr', 'Tradorec xl', 'Tramace... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1575 | Q6 | What genes does Ticagrelor target when it's used to treat stroke? | When used to treat stroke, the drug Ticagrelor targets the gene P2RY12. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ticagrelor%" OR LOWER(tradeNames_list) LIKE "%tic... | [{'UUID': 'DrugTargetsIndication121923_text_920466', 'drugName': 'Ticagrelor', 'tradeNames_list': "['Brilinta', 'Brilique']", 'syns_list': "['AR-C126532XX', 'AZD-6140', 'AZD6140', 'Possia', 'Ticagrelor']", 'target': 'ENSG00000169313', 'approvedSymbol': 'P2RY12', 'approvedName': 'purinergic receptor P2Y12', 'mesh_headin... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1865 | Q6 | What genes does Cyclobenzaprine Hydrochloride target when it's used to treat cerebral palsy? | When used to treat cerebral palsy, the drug Cyclobenzaprine Hydrochloride targets the genes HTR2C and HTR2A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%cyclobenzaprine hydrochloride%" OR LOWER(tradeNam... | [{'UUID': 'DrugTargetsIndication121923_text_151280', 'drugName': 'Cyclobenzaprine Hydrochloride', 'tradeNames_list': "['Amrix', 'Cyclobenzaprine hydrochloride', 'Flexeril']", 'syns_list': "['Cyclobenzaprine hcl', 'Cyclobenzaprine hydrochloride', 'MK-130MK-130 HYDROCHLORIDE', 'MK-130 [AS THE BASE]', 'NSC-169900', 'NSC-1... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1749 | Q6 | What genes does Dimethyl Fumarate target when it's used to treat immune system disease? | When used to treat immune system disease, the drug Dimethyl Fumarate targets the gene KEAP1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dimethyl fumarate%" OR LOWER(tradeNames_list) LIK... | [{'UUID': 'DrugTargetsIndication121923_text_1055756', 'drugName': 'Dimethyl Fumarate', 'tradeNames_list': "['Tecfidera']", 'syns_list': "['AZL 0 211089', 'AZL O 211089', 'AZL-0211089', 'AZL-O-211089', 'BG 00012BG 12', 'BG-00012', 'BG-12', 'BG00012', 'Dimethyl fumar', 'Dimethyl fumarateFAG-201', 'FP-187', 'FP187', 'Fuma... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.718 | Q6 | What genes does Naproxen Sodium target when it's used to treat pain? | When used to treat pain, the drug Naproxen Sodium targets the genes PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%naproxen sodium%" OR LOWER(tradeNames_list) LIKE ... | [{'UUID': 'DrugTargetsIndication121923_text_838064', 'drugName': 'Naproxen Sodium', 'tradeNames_list': "['Aleve', 'Anaprox', 'Anaprox ds', 'Naprelan', 'Naproxen sodium', 'Synflex']", 'syns_list': "['BAY-117031', 'BAY117031', 'BAYH6689', 'Naproxen sodiumNaproxen sodium anhydrous', 'Naproxen sodium salt', 'RS-3650']", 't... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1936 | Q6 | What genes does Fostamatinib Disodium target when it's used to treat autoimmune thrombocytopenic purpura? | When used to treat autoimmune thrombocytopenic purpura, the drug Fostamatinib Disodium targets the gene SYK. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fostamatinib disodium%" OR LOWER(tradeNames_list)... | [{'UUID': 'DrugTargetsIndication121923_text_848773', 'drugName': 'Fostamatinib Disodium', 'tradeNames_list': "['Tavalisse']", 'syns_list': "['Fostamatinib disodium', 'Fostamatinib disodium hexahydrateFostamatinib disodium salt hexahydrate', 'Fostamatinib sodium hydrateR-788 SODIUM', 'R-788 SODIUM HYDRATE', 'R-935788 SO... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.852 | Q6 | What genes does Naproxen target when it's used to treat rheumatoid arthritis? | When used to treat rheumatoid arthritis, the drug Naproxen targets the genes PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%naproxen%" OR LOWER(tradeNames_list) LIKE "%napro... | [{'UUID': 'DrugTargetsIndication121923_text_838129', 'drugName': 'Naproxen Sodium', 'tradeNames_list': "['Aleve', 'Anaprox', 'Anaprox ds', 'Naprelan', 'Naproxen sodium', 'Synflex']", 'syns_list': "['BAY-117031', 'BAY117031', 'BAYH6689', 'Naproxen sodiumNaproxen sodium anhydrous', 'Naproxen sodium salt', 'RS-3650']", 't... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1938 | Q6 | What genes does Copanlisib Hydrochloride target when it's used to treat follicular lymphoma? | When used to treat follicular lymphoma, the drug Copanlisib Hydrochloride targets the genes PIK3CD and PIK3CA. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%copanlisib hydrochloride%" OR LOWER(tradeNames_li... | [{'UUID': 'DrugTargetsIndication121923_text_858361', 'drugName': 'Copanlisib Hydrochloride', 'tradeNames_list': "['Aliqopa']", 'syns_list': "['BAY 80-6946 DIHYDROCHLORIDE', 'BAY 84-1236', 'BAY-80-6946 DIHYDROCHLORIDEBAY-84-1236', 'Copanlisib dihydrochloride', 'Copanlisib hydrochlorideCopanlisib hydrochloride hydrate']"... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.11 | Q6 | What genes does Everolimus target when it's used to treat Adenoma sebaceum? | When used to treat Adenoma sebaceum, the drug Everolimus targets the gene FKBP1A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%everolimus%" OR LOWER(tradeNames_list) LIKE "%eve... | [{'UUID': 'DrugTargetsIndication121923_text_1085627', 'drugName': 'Everolimus', 'tradeNames_list': "['Afinitor', 'Afinitor disperz', 'Certican', 'Votubia', 'Zortress']", 'syns_list': "['40-o-(2-hydroxyethyl)-rapamycin', 'Everolimus', 'RAD 666', 'RAD-001RAD-666', 'RAD001', 'SDZ-RAD', 'Sdz rad']", 'target': 'ENSG00000088... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1695 | Q6 | What genes does Fluticasone Propionate target when it's used to treat emphysema? | When used to treat emphysema, the drug Fluticasone Propionate targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fluticasone propionate%" OR LOWER(tradeNames_list... | [{'UUID': 'DrugTargetsIndication121923_text_232530', 'drugName': 'Fluticasone Propionate', 'tradeNames_list': "['Aerivio spiromax', 'Airflusal forspiro', 'Armonair digihalerArmonair respiclick', 'Cutivate', 'Flixonase', 'Flixotide', 'FlonaseFlonase allergy relief', 'Flovent', 'Flovent diskus 100Flovent diskus 250', 'Fl... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1124 | Q6 | What genes does Crisaborole target when it's used to treat atopic eczema? | When used to treat atopic eczema, the drug Crisaborole targets the genes PDE4A, PDE4D, PDE4B, and PDE4C. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%crisaborole%" OR LOWER(tradeNames_list) LIKE "%cr... | [{'UUID': 'DrugTargetsIndication121923_text_696585', 'drugName': 'Crisaborole', 'tradeNames_list': "['Eucrisa']", 'syns_list': "['AN-2728', 'AN2728', 'Crisaborole']", 'target': 'ENSG00000065989', 'approvedSymbol': 'PDE4A', 'approvedName': 'phosphodiesterase 4A', 'mesh_heading': 'Dermatitis, Atopic', 'efo_term': 'atopic... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.286 | Q6 | What genes does Ixazomib Citrate target when it's used to treat cancer? | When used to treat cancer, the drug Ixazomib Citrate targets the genes PSMD1, PSMB2, PSMB1, PSMB5, PSMB8, PSMB9, PSMB6, PSMD14, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMA7, PSMA8, PSMB10, PSMB11, PSMB3, PSMB4, PSMB7, ADRM1, PSMC2, PSMC1, PSMC4, PSMC6, PSMC3, PSMC5, PSMD2, PSMD3, PSMD12, PSMD11, PSMD6, PSMD7, PSMD13... | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ixazomib citrate%" OR LOWER(tradeNames_list) LIKE... | [{'UUID': 'DrugTargetsIndication121923_text_327570', 'drugName': 'Ixazomib Citrate', 'tradeNames_list': "['Ninlaro']", 'syns_list': "['Ixazomib citrate', 'MLN-9708', 'MLN9708']", 'target': 'ENSG00000008018', 'approvedSymbol': 'PSMB1', 'approvedName': 'proteasome 20S subunit beta 1', 'mesh_heading': 'Neoplasms', 'efo_te... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.817 | Q6 | What genes does Regorafenib target when it's used to treat renal cell carcinoma? | Regorafenib has not been approved by the FDA as a treatment for renal cell carcinoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are KDR, FGFR1, FGFR2, ABL1, BRAF, TEK, FLT1, KIT, FLT4, PDGFRB, PDGFRA, RAF1, EPHA2, FRK, NTRK1, RET, DDR2, and MAPK11. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%regorafenib%" OR LOWER(tradeNames_list) LIKE "%re... | [{'UUID': 'DrugTargetsIndication121923_text_664222', 'drugName': 'Regorafenib', 'tradeNames_list': "['Stivarga']", 'syns_list': "['BAY 73-4506', 'BAY 73-4506 monohydrate', 'BAY-73-4506', 'BAY-734506Regorafenib', 'Regorafenib anhydrous', 'Regorafenib hydrateRegorafenib monohydrate']", 'target': 'ENSG00000077782', 'appro... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1092 | Q6 | What genes does Ambrisentan target when it's used to treat pulmonary arterial hypertension? | When used to treat pulmonary arterial hypertension, the drug Ambrisentan targets the genes EDNRA and EDNRB. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ambrisentan%" OR LOWER(tradeNames_list) LIKE "%am... | [{'UUID': 'DrugTargetsIndication121923_text_1084063', 'drugName': 'Ambrisentan', 'tradeNames_list': "['Letairis', 'Volibris']", 'syns_list': "['Ambrisentan', 'GSK-1325760', 'GSK-1325760A', 'GSK1325760', 'GSK1325760ALU-208075']", 'target': 'ENSG00000151617', 'approvedSymbol': 'EDNRA', 'approvedName': 'endothelin recepto... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.295 | Q6 | What genes does Testosterone target when it's used to treat Klinefelter's syndrome? | When used to treat Klinefelter's syndrome, the drug Testosterone targets the gene AR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%testosterone%" OR LOWER(tradeNames_list) LIKE "%t... | [{'UUID': 'DrugTargetsIndication121923_text_922038', 'drugName': 'Testosterone Undecanoate', 'tradeNames_list': "['Andriol', 'Aveed', 'Jatenzo', 'Kyzatrex', 'Nebido', 'RestandolRestandol testocap', 'Tlando', 'Undestor']", 'syns_list': "['Kyzatrex', 'MK-3033', 'ORG 538', 'ORG-538', 'TSX-011Testosterone 17.beta.-undecyla... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.761 | Q6 | What genes does Ribavirin target when it's used to treat hemorrhagic fever with renal syndrome? | Ribavirin has not been approved by the FDA as a treatment for hemorrhagic fever with renal syndrome, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is IMPDH1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ribavirin%" OR LOWER(tradeNames_list) LIKE "%riba... | [{'UUID': 'DrugTargetsIndication121923_text_937547', 'drugName': 'Ribavirin', 'tradeNames_list': "['Copegus', 'Rebetol', 'Ribapak', 'Ribasphere', 'Ribavarin', 'RibavirinRibofluranosyl Carboxamide', 'Tribavirin', 'Viramid', 'Virazid', 'Virazole']", 'syns_list': "['Cotronak', 'NSC-163039', 'Ribavirin', 'Ribavirin biopart... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.633 | Q6 | What genes does Vorapaxar Sulfate target when it's used to treat peripheral arterial disease? | When used to treat peripheral arterial disease, the drug Vorapaxar Sulfate targets the gene F2R. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%vorapaxar sulfate%" OR LOWER(tradeNames_list) LIK... | [{'UUID': 'DrugTargetsIndication121923_text_1193356', 'drugName': 'Vorapaxar Sulfate', 'tradeNames_list': "['Zontivity']", 'syns_list': "['SCH 530348', 'SCH-530348', 'Vorapaxar sulfate']", 'target': 'ENSG00000181104', 'approvedSymbol': 'F2R', 'approvedName': 'coagulation factor II thrombin receptor', 'mesh_heading': 'P... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.930 | Q6 | What genes does Plerixafor target when it's used to treat diabetic foot? | Plerixafor has not been approved by the FDA as a treatment for diabetic foot, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is CXCR4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%plerixafor%" OR LOWER(tradeNames_list) LIKE "%ple... | [{'UUID': 'DrugTargetsIndication121923_text_1103187', 'drugName': 'Plerixafor', 'tradeNames_list': "['Mozobil']", 'syns_list': "['AMD 3100', 'AMD3100', 'JM 3100', 'Plerixafor', 'Plerixafor hydrochloridePlerixafor octahydrochloride', 'SID 791']", 'target': 'ENSG00000121966', 'approvedSymbol': 'CXCR4', 'approvedName': 'C... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1019 | Q6 | What genes does Indomethacin target when it's used to treat gout? | When used to treat gout, the drug Indomethacin targets the genes PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%indomethacin%" OR LOWER(tradeNames_list) LIKE "%i... | [{'UUID': 'DrugTargetsIndication121923_text_828374', 'drugName': 'Indomethacin', 'tradeNames_list': "['Artracin', 'Artracin sr', 'Berlind 75 ret', 'Flexin-25 continusFlexin-50 continus', 'Flexin-75 continus', 'Imbrilon', 'Indo-lemmonIndo-paed', 'Indocid ret', 'Indocid-r', 'Indocin', 'Indocin sr', 'IndodermIndoflex', 'I... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.132 | Q6 | What genes does Budesonide target when it's used to treat respiratory system disease? | Budesonide has not been approved by the FDA as a treatment for respiratory system disease, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%budesonide%" OR LOWER(tradeNames_list) LIKE "%bud... | [{'UUID': 'DrugTargetsIndication121923_text_222593', 'drugName': 'Budesonide', 'tradeNames_list': "['Aircort', 'Budeflam aquanase', 'Budelin novolizer', 'BudenofalkBudesonide', 'Cortiment', 'Duoresp spiromax', 'Entocort', 'Entocort crEntocort ec', 'Ortikos', 'Preferid', 'Pulmaxan', 'PulmicortPulmicort flexhaler', 'Pulm... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1175 | Q6 | What genes does Triamcinolone Acetonide target when it's used to treat seasonal allergic rhinitis? | When used to treat seasonal allergic rhinitis, the drug Triamcinolone Acetonide targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%triamcinolone acetonide%" OR LOWER(tradeNames_lis... | [{'UUID': 'DrugTargetsIndication121923_text_222202', 'drugName': 'Triamcinolone Acetonide', 'tradeNames_list': "['Adcortyl', 'Adcortyl in orabase', 'Allernaze', 'Aristocort', 'Aristocort aAristogel', 'Audicort', 'Aureocort', 'Azmacort', 'Flutex', 'Gppe ear dps capGppe ear oint', 'Kenacort', 'Kenalog', 'Kenalog in oraba... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.327 | Q6 | What genes does Linagliptin target when it's used to treat Renal insufficiency? | Linagliptin has not been approved by the FDA as a treatment for Renal insufficiency, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is DPP4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%linagliptin%" OR LOWER(tradeNames_list) LIKE "%li... | [{'UUID': 'DrugTargetsIndication121923_text_932948', 'drugName': 'Linagliptin', 'tradeNames_list': "['Tradjenta', 'Trajenta']", 'syns_list': "['BI 1356', 'BI 1356 BS', 'BI-1356', 'BI-1356-BS', 'BI-1356BS', 'BS 1356 BSBS-1356-BS', 'Linagliptin', 'Trazenta']", 'target': 'ENSG00000197635', 'approvedSymbol': 'DPP4', 'appro... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1279 | Q6 | What genes does Dexamethasone target when it's used to treat allergic conjunctivitis? | When used to treat allergic conjunctivitis, the drug Dexamethasone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dexamethasone%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_227772', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1385 | Q6 | What genes does Vorinostat target when it's used to treat leukemia? | Vorinostat has not been approved by the FDA as a treatment for leukemia, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are HDAC1, HDAC3, HDAC6, and HDAC2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%vorinostat%" OR LOWER(tradeNames_list) LIKE "%vor... | [{'UUID': 'DrugTargetsIndication121923_text_1077131', 'drugName': 'Vorinostat', 'tradeNames_list': "['Zolinza']", 'syns_list': "['MK-0683', 'MK0683', 'NSC-701852', 'NSC-748799', 'NSC-759852Suberoylanilide hydroxamic acid', 'Vorinostat']", 'target': 'ENSG00000116478', 'approvedSymbol': 'HDAC1', 'approvedName': 'histone ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.951 | Q6 | What genes does Topotecan Hydrochloride target when it's used to treat ovarian carcinoma? | When used to treat ovarian carcinoma, the drug Topotecan Hydrochloride targets the gene TOP1MT. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%topotecan hydrochloride%" OR LOWER(tradeNames_lis... | [{'UUID': 'DrugTargetsIndication121923_text_1193574', 'drugName': 'Topotecan Hydrochloride', 'tradeNames_list': "['Hycamptin', 'Hycamtin', 'Topotecan', 'Topotecan hydrochloride']", 'syns_list': "['Evotopin', 'NSC-759263', 'Nogitecan hydrochloride', 'SK&F S-104864-ASK&F-S-104864A', 'SK-S-104864-A', 'Topotecan (as hydroc... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1867 | Q6 | What genes does Afamelanotide target when it's used to treat erythropoietic protoporphyria? | When used to treat erythropoietic protoporphyria, the drug Afamelanotide targets the gene MC1R. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%afamelanotide%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_1097737', 'drugName': 'Afamelanotide', 'tradeNames_list': "['Scenesse']", 'syns_list': "['Afamelanotide', 'CUV-1647', 'CUV1647', 'Melanotan', 'Melanotan iMelanotan-1']", 'target': 'ENSG00000258839', 'approvedSymbol': 'MC1R', 'approvedName': 'melanocortin 1 receptor', 'mesh_he... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1372 | Q6 | What genes does Vandetanib target when it's used to treat gastrointestinal stromal tumor? | Vandetanib has not been approved by the FDA as a treatment for gastrointestinal stromal tumor, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are EGFR, ERBB3, KDR, SRC, TEK, ERBB2, FLT1, FLT4, EPHA2, RET, ERBB4, EPHB4, PTK6, EPHB2, EPHA5, EPHA4, EPHA8, EPHA6, EP... | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%vandetanib%" OR LOWER(tradeNames_list) LIKE "%van... | [{'UUID': 'DrugTargetsIndication121923_text_210181', 'drugName': 'Vandetanib', 'tradeNames_list': "['Caprelsa', 'Zactima']", 'syns_list': "['GNF-PF-2188', 'NSC-744325', 'NSC-760766', 'Vandetanib', 'ZD-64', 'ZD-6474ZD6474']", 'target': 'ENSG00000146648', 'approvedSymbol': 'EGFR', 'approvedName': 'epidermal growth factor... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1520 | Q6 | What genes does Triamcinolone Acetonide target when it's used to treat gout? | When used to treat gout, the drug Triamcinolone Acetonide targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%triamcinolone acetonide%" OR LOWER(tradeNames_lis... | [{'UUID': 'DrugTargetsIndication121923_text_222203', 'drugName': 'Triamcinolone Acetonide', 'tradeNames_list': "['Adcortyl', 'Adcortyl in orabase', 'Allernaze', 'Aristocort', 'Aristocort aAristogel', 'Audicort', 'Aureocort', 'Azmacort', 'Flutex', 'Gppe ear dps capGppe ear oint', 'Kenacort', 'Kenalog', 'Kenalog in oraba... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.702 | Q6 | What genes does Relugolix target when it's used to treat endometriosis? | Relugolix has not been approved by the FDA as a treatment for endometriosis, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is GNRHR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%relugolix%" OR LOWER(tradeNames_list) LIKE "%relu... | [{'UUID': 'DrugTargetsIndication121923_text_1096981', 'drugName': 'Relugolix', 'tradeNames_list': "['Orgovyx']", 'syns_list': "['Relugolix', 'TAK-385', 'Tak-385']", 'target': 'ENSG00000109163', 'approvedSymbol': 'GNRHR', 'approvedName': 'gonadotropin releasing hormone receptor', 'mesh_heading': 'Endometriosis', 'efo_te... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.218 | Q6 | What genes does Entrectinib target when it's used to treat neoplasm? | When used to treat neoplasm, the drug Entrectinib targets the genes NTRK1, ALK, NTRK2, NTRK3, and ROS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%entrectinib%" OR LOWER(tradeNames_list) LIKE "%en... | [{'UUID': 'DrugTargetsIndication121923_text_942980', 'drugName': 'Entrectinib', 'tradeNames_list': "['Rozlytrek']", 'syns_list': "['Entrectinib', 'NMS-E628', 'RXDX-101', 'Rxdx-101']", 'target': 'ENSG00000198400', 'approvedSymbol': 'NTRK1', 'approvedName': 'neurotrophic receptor tyrosine kinase 1', 'mesh_heading': 'Neop... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1043 | Q6 | What genes does Brexpiprazole target when it's used to treat schizophrenia? | When used to treat schizophrenia, the drug Brexpiprazole targets the genes DRD2, HTR2A, and HTR1A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%brexpiprazole%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_155835', 'drugName': 'Brexpiprazole', 'tradeNames_list': "['Rexulti']", 'syns_list': "['Brexpiprazole', 'OPC-34712']", 'target': 'ENSG00000149295', 'approvedSymbol': 'DRD2', 'approvedName': 'dopamine receptor D2', 'mesh_heading': 'Schizophrenia', 'efo_term': 'schizophrenia', ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1815 | Q6 | What genes does Prednisone target when it's used to treat allergic rhinitis? | When used to treat allergic rhinitis, the drug Prednisone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%prednisone%" OR LOWER(tradeNames_list) LIKE "%pre... | [{'UUID': 'DrugTargetsIndication121923_text_218065', 'drugName': 'Prednisone', 'tradeNames_list': "['Cortan', 'Cortancyl', 'Decortisyl', 'Delta-dome', 'Deltasone', 'FernisoneLiquid pred', 'Lodotra', 'Meticorten', 'Orasone', 'Paracort', 'Prednicen-mPrednisone', 'Prednisone intensol', 'Rayos', 'Servisone', 'Sterapred']",... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.161 | Q6 | What genes does Drospirenone target when it's used to treat acne? | When used to treat acne, the drug Drospirenone targets the genes PGR and NR3C2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%drospirenone%" OR LOWER(tradeNames_list) LIKE "%d... | [{'UUID': 'DrugTargetsIndication121923_text_939886', 'drugName': 'Drospirenone', 'tradeNames_list': "['Angeliq', 'Slynd']", 'syns_list': "['Drospirenone', 'NSC-760103', 'ZK 30595', 'ZK-30595']", 'target': 'ENSG00000082175', 'approvedSymbol': 'PGR', 'approvedName': 'progesterone receptor', 'mesh_heading': 'Acne Vulgaris... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1059 | Q6 | What genes does Diazepam target when it's used to treat epilepsy? | When used to treat epilepsy, the drug Diazepam targets the genes GABRA1, GABRB2, GABRG2, GABRB3, GABRA4, GABRG3, GABRQ, GABRA3, GABRP, GABRD, GABRG1, GABRB1, GABRE, GABRA2, GABRA5, and GABRA6. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%diazepam%" OR LOWER(tradeNames_list) LIKE "%diaze... | [{'UUID': 'DrugTargetsIndication121923_text_961707', 'drugName': 'Diazepam', 'tradeNames_list': "['Alupram 10', 'Alupram 2', 'Alupram 5', 'Apozepam', 'Atensine', 'DialarDialar fte', 'Diastat', 'Diastat acudial', 'Diazepam', 'Diazepam intensolDizac', 'E-Pam', 'Paxel', 'Q-pam', 'Relanium', 'Scriptopam', 'SerenackSolis', ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1243 | Q6 | What genes does Venetoclax target when it's used to treat neoplasm of mature B-cells? | Venetoclax has not been approved by the FDA as a treatment for neoplasm of mature B-cells, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is BCL2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%venetoclax%" OR LOWER(tradeNames_list) LIKE "%ven... | [{'UUID': 'DrugTargetsIndication121923_text_989857', 'drugName': 'Venetoclax', 'tradeNames_list': "['Venclexta']", 'syns_list': "['ABT-199', 'GDC-0199', 'RG-7601', 'RG7601', 'Venetoclax']", 'target': 'ENSG00000171791', 'approvedSymbol': 'BCL2', 'approvedName': 'BCL2 apoptosis regulator', 'mesh_heading': 'Lymphoma, Foll... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.641 | Q6 | What genes does Midazolam target when it's used to treat skin disease? | Midazolam has not been approved by the FDA as a treatment for skin disease, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are GABRA1, GABRB2, GABRG2, GABRB3, GABRA4, GABRG3, GABRQ, GABRA3, GABRP, GABRD, GABRG1, GABRB1, GABRE, GABRA2, GABRA5, and GABRA6. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%midazolam%" OR LOWER(tradeNames_list) LIKE "%mida... | [{'UUID': 'DrugTargetsIndication121923_text_948976', 'drugName': 'Midazolam', 'tradeNames_list': "['Midazolam in 0.8% sodium chloride', 'Midazolam in 0.9% sodium chlorideNayzilam']", 'syns_list': "['Midazolam', 'Midazolam civ', 'USL-261', 'USL261']", 'target': 'ENSG00000022355', 'approvedSymbol': 'GABRA1', 'approvedNam... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.522 | Q6 | What genes does Aspirin target when it's used to treat Dysmenorrhea? | When used to treat Dysmenorrhea, the drug Aspirin targets the genes PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%aspirin%" OR LOWER(tradeNames_list) LIKE "%aspiri... | [{'UUID': 'DrugTargetsIndication121923_text_834430', 'drugName': 'Aspirin', 'tradeNames_list': "['8-hour bayer', 'Acetosalic Acid', 'Acetylsalic acidAcetylsalicylic Acid', 'Alka rapid', 'Anadin all night', 'Angettes 75Aspirin', 'Aspro clr', 'Bayer extra strength aspirin for migraine painDanamep', 'Disprin cv', 'Disprin... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1624 | Q6 | What genes does Prednisone target when it's used to treat leukemia? | When used to treat leukemia, the drug Prednisone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%prednisone%" OR LOWER(tradeNames_list) LIKE "%pre... | [{'UUID': 'DrugTargetsIndication121923_text_220543', 'drugName': 'Prednisone', 'tradeNames_list': "['Cortan', 'Cortancyl', 'Decortisyl', 'Delta-dome', 'Deltasone', 'FernisoneLiquid pred', 'Lodotra', 'Meticorten', 'Orasone', 'Paracort', 'Prednicen-mPrednisone', 'Prednisone intensol', 'Rayos', 'Servisone', 'Sterapred']",... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1522 | Q6 | What genes does Mipomersen Sodium target when it's used to treat familial hypercholesterolemia? | When used to treat familial hypercholesterolemia, the drug Mipomersen Sodium targets the gene APOB. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%mipomersen sodium%" OR LOWER(tradeNames_list) LIK... | [{'UUID': 'DrugTargetsIndication121923_text_1191789', 'drugName': 'Mipomersen Sodium', 'tradeNames_list': "['Kynamro']", 'syns_list': "['ISIS 301012', 'ISIS-301012', 'Mipomersen sodium', 'Mipomersen sodium salt']", 'target': 'ENSG00000084674', 'approvedSymbol': 'APOB', 'approvedName': 'apolipoprotein B', 'mesh_heading'... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.604 | Q6 | What genes does Apixaban target when it's used to treat stroke? | When used to treat stroke, the drug Apixaban targets the gene F10. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%apixaban%" OR LOWER(tradeNames_list) LIKE "%apixa... | [{'UUID': 'DrugTargetsIndication121923_text_710478', 'drugName': 'Apixaban', 'tradeNames_list': "['Eliquis']", 'syns_list': "['Apixaban', 'BMS-562247', 'BMS-562247-01']", 'target': 'ENSG00000126218', 'approvedSymbol': 'F10', 'approvedName': 'coagulation factor X', 'mesh_heading': 'Stroke', 'efo_term': 'stroke', 'yearOf... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.198 | Q6 | What genes does Loteprednol Etabonate target when it's used to treat dry eye syndrome? | When used to treat dry eye syndrome, the drug Loteprednol Etabonate targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%loteprednol etabonate%" OR LOWER(tradeNames_list)... | [{'UUID': 'DrugTargetsIndication121923_text_225457', 'drugName': 'Loteprednol Etabonate', 'tradeNames_list': "['Airex', 'Alrex', 'Eysuvis', 'Inveltys', 'Lotemax', 'Lotemax sm']", 'syns_list': "['CDDD 5604', 'CDDD-5604', 'HGP-1', 'KPI-121', 'LoteprednolLoteprednol etabonate', 'P-5604']", 'target': 'ENSG00000113580', 'ap... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1644 | Q6 | What genes does Ibuprofen target when it's used to treat orthostatic hypotension? | Ibuprofen has not been approved by the FDA as a treatment for orthostatic hypotension, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ibuprofen%" OR LOWER(tradeNames_list) LIKE "%ibup... | [{'UUID': 'DrugTargetsIndication121923_text_840101', 'drugName': 'Ibuprofen', 'tradeNames_list': '[\'Aches-n-pain\', \'Advil\', \'Advil liqui-gels\', \'Advil migraine liqui-gelsAnadin joint pain\', \'Anadin liquifast\', \'Anadin period pain reliefAnadin ultra\', \'Apsifen\', \'Apsifen-f\', \'Arthrofen 200\', \'Arthrofe... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.961 | Q6 | What genes does Methylphenidate target when it's used to treat narcolepsy-cataplexy syndrome? | When used to treat narcolepsy-cataplexy syndrome, the drug Methylphenidate targets the genes SLC6A2 and SLC6A3. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%methylphenidate%" OR LOWER(tradeNames_list) LIKE ... | [{'UUID': 'DrugTargetsIndication121923_text_439366', 'drugName': 'Methylphenidate', 'tradeNames_list': "['Concerta', 'Cotempla xr-odt', 'Daytrana']", 'syns_list': "['Concerta', 'Methylin', 'MethylphenidateMethylphenidate extended release', 'Prc-063', 'Threo-dl-methylphenidate']", 'target': 'ENSG00000103546', 'approvedS... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.416 | Q6 | What genes does Levomilnacipran Hydrochloride target when it's used to treat fibromyalgia? | When used to treat fibromyalgia, the drug Levomilnacipran Hydrochloride targets the genes SLC6A4 and SLC6A2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%levomilnacipran hydrochloride%" OR LOWER(tradeNam... | [{'UUID': 'DrugTargetsIndication121923_text_206893', 'drugName': 'Levomilnacipran Hydrochloride', 'tradeNames_list': "['Fetzima']", 'syns_list': "['(1s,2r)-milnacipran hydrochloride', 'F 2695 HYDROCHLORIDEF-2695 HYDROCHLORIDE', 'F2695', 'F2695 HYDROCHLORIDELevomilnacipran hydrochloride']", 'target': 'ENSG00000108576', ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.99 | Q6 | What genes does Estradiol target when it's used to treat Dysmenorrhea? | Estradiol has not been approved by the FDA as a treatment for Dysmenorrhea, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is ESR1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%estradiol%" OR LOWER(tradeNames_list) LIKE "%estr... | [{'UUID': 'DrugTargetsIndication121923_text_824156', 'drugName': 'Estradiol', 'tradeNames_list': "['Adgyn estro', 'Alora', 'Aquagen', 'Bedol', 'Climara', 'Climara ProDermestril 100', 'Dermestril 25', 'Dermestril 50', 'Dermestril septem 25Dermestril septem 50', 'Dermestril septem 75', 'Divigel', 'E-CypionateElestrim', '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.988 | Q6 | What genes does Aspirin target when it's used to treat gastric ulcer? | Aspirin has not been approved by the FDA as a treatment for gastric ulcer, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%aspirin%" OR LOWER(tradeNames_list) LIKE "%aspiri... | [{'UUID': 'DrugTargetsIndication121923_text_834395', 'drugName': 'Aspirin', 'tradeNames_list': "['8-hour bayer', 'Acetosalic Acid', 'Acetylsalic acidAcetylsalicylic Acid', 'Alka rapid', 'Anadin all night', 'Angettes 75Aspirin', 'Aspro clr', 'Bayer extra strength aspirin for migraine painDanamep', 'Disprin cv', 'Disprin... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.933 | Q6 | What genes does Capsaicin target when it's used to treat frozen shoulder? | When used to treat frozen shoulder, the drug Capsaicin targets the gene TRPV1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%capsaicin%" OR LOWER(tradeNames_list) LIKE "%caps... | [{'UUID': 'DrugTargetsIndication121923_text_993230', 'drugName': 'Capsaicin', 'tradeNames_list': "['Qutenza', 'Zacin', 'Zostrix', 'Zostrix hp']", 'syns_list': "['ALGRX 4975', 'ALGRX-4975', 'Ausanil', 'Axsain', 'Capsaicin', 'Capzasin-hpCntx-4975', 'Dolenon', 'FEMA NO. 3404', 'Mioton', 'NGX-1998', 'NGX-4010NSC-56353', 'N... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.159 | Q6 | What genes does Nitroglycerin target when it's used to treat pain? | When used to treat pain, the drug Nitroglycerin targets the genes GUCY1B1, GUCY1B2, GUCY1A2, and GUCY1A1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%nitroglycerin%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_972650', 'drugName': 'Nitroglycerin', 'tradeNames_list': "['Coro-nitro', 'Deponit 10', 'Deponit 5', 'Glytrin', 'Gonitro', 'Lenitral 7.5Minitran', 'Minitran 10', 'Minitran 15', 'Minitran 5', 'NatiroseNitriderm tts', 'Nitro iv', 'Nitro-bid', 'Nitro-dur', 'Nitro-mack retNitrocin... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.425 | Q6 | What genes does Oxymetazoline Hydrochloride target when it's used to treat ptosis? | When used to treat ptosis, the drug Oxymetazoline Hydrochloride targets the genes ADRA1A, ADRA1D, ADRA1B, ADRA2A, ADRA2C, and ADRA2B. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%oxymetazoline hydrochloride%" OR LOWER(tradeNames... | [{'UUID': 'DrugTargetsIndication121923_text_417245', 'drugName': 'Oxymetazoline Hydrochloride', 'tradeNames_list': "['Afrazine', 'Ocuclear', 'Rhofade', 'Upneeq', 'Visine', 'Visine l.r.']", 'syns_list': "['Agn-199201', 'NSC-757254', 'Oximetazoline hydrochlorideOxymetazoline hcl', 'Oxymetazoline hydrochloride', 'SCH 9384... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1804 | Q6 | What genes does Enalapril Maleate target when it's used to treat heart failure? | When used to treat heart failure, the drug Enalapril Maleate targets the gene ACE. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%enalapril maleate%" OR LOWER(tradeNames_list) LIK... | [{'UUID': 'DrugTargetsIndication121923_text_1091877', 'drugName': 'Enalapril Maleate', 'tradeNames_list': "['Ednyt', 'Enalapril maleate', 'Enapren', 'Epaned', 'Epaned kit', 'InnovacePralenal 10', 'Pralenal 2.5', 'Pralenal 20', 'Pralenal 5', 'RenitecVasotec', 'Xanef']", 'syns_list': "['Enalapril maleate', 'MK-421', 'NSC... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.483 | Q6 | What genes does Tirofiban Hydrochloride target when it's used to treat myocardial infarction? | When used to treat myocardial infarction, the drug Tirofiban Hydrochloride targets the genes ITGB3 and ITGA2B. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%tirofiban hydrochloride%" OR LOWER(tradeNames_lis... | [{'UUID': 'DrugTargetsIndication121923_text_1095575', 'drugName': 'Tirofiban Hydrochloride', 'tradeNames_list': "['Aggrastat']", 'syns_list': "['L-700,462', 'L-700462', 'MK-383', 'Tirofiban hcl', 'Tirofiban hydrochlorideTirofiban hydrochloride anhydrous']", 'target': 'ENSG00000005961', 'approvedSymbol': 'ITGA2B', 'appr... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1512 | Q6 | What genes does Pomalidomide target when it's used to treat AL amyloidosis? | Pomalidomide has not been approved by the FDA as a treatment for AL amyloidosis, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are CRBN, DDB1, CUL4A, and RBX1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%pomalidomide%" OR LOWER(tradeNames_list) LIKE "%p... | [{'UUID': 'DrugTargetsIndication121923_text_1141324', 'drugName': 'Pomalidomide', 'tradeNames_list': "['Imnovid', 'Pomalyst']", 'syns_list': "['Actimid', 'CC-4047', 'IMID 3', 'IMID-3', 'Pomalidomide']", 'target': 'ENSG00000113851', 'approvedSymbol': 'CRBN', 'approvedName': 'cereblon', 'mesh_heading': 'Amyloidosis, Fami... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.675 | Q6 | What genes does Lenalidomide target when it's used to treat immune system disease? | When used to treat immune system disease, the drug Lenalidomide targets the genes CRBN, DDB1, CUL4A, and RBX1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lenalidomide%" OR LOWER(tradeNames_list) LIKE "%l... | [{'UUID': 'DrugTargetsIndication121923_text_1106170', 'drugName': 'Lenalidomide', 'tradeNames_list': "['Revlimid']", 'syns_list': "['CC-5013', 'CDC-501', 'Lenalidomide', 'NSC-747972', 'SYP-1512']", 'target': 'ENSG00000113851', 'approvedSymbol': 'CRBN', 'approvedName': 'cereblon', 'mesh_heading': 'Immune System Diseases... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1238 | Q6 | What genes does Levomilnacipran target when it's used to treat unipolar depression? | When used to treat unipolar depression, the drug Levomilnacipran targets the genes SLC6A4 and SLC6A2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%levomilnacipran%" OR LOWER(tradeNames_list) LIKE ... | [{'UUID': 'DrugTargetsIndication121923_text_206892', 'drugName': 'Levomilnacipran Hydrochloride', 'tradeNames_list': "['Fetzima']", 'syns_list': "['(1s,2r)-milnacipran hydrochloride', 'F 2695 HYDROCHLORIDEF-2695 HYDROCHLORIDE', 'F2695', 'F2695 HYDROCHLORIDELevomilnacipran hydrochloride']", 'target': 'ENSG00000108576', ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1873 | Q6 | What genes does Amlodipine Besylate target when it's used to treat Hypercholesterolemia? | When used to treat Hypercholesterolemia, the drug Amlodipine Besylate targets the genes CACNA1C, CACNA1S, CACNA1D, and CACNA1F. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%amlodipine besylate%" OR LOWER(tradeNames_list) L... | [{'UUID': 'DrugTargetsIndication121923_text_1043698', 'drugName': 'Amlodipine Besylate', 'tradeNames_list': "['Amlodipine besylate', 'Norliqva', 'Norvasc']", 'syns_list': "['Amlodipine (as besilate)', 'Amlodipine benzenesulfonateAmlodipine besilate', 'Amlodipine besylate', 'Amlor', 'AntacalLodipressin', 'Monopina', 'NS... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1299 | Q6 | What genes does Lidocaine target when it's used to treat Tinnitus? | Lidocaine has not been approved by the FDA as a treatment for Tinnitus, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lidocaine%" OR LOWER(tradeNames_list) LIKE "%lido... | [{'UUID': 'DrugTargetsIndication121923_text_638373', 'drugName': 'Lidocaine', 'tradeNames_list': "['Alphacaine', 'Anestacon', 'Dentipatch', 'Lidocaine', 'LidodermLignocaine Hcl', 'Lignostab', 'Lmx 4', 'Oraqix', 'Vagisil', 'XylocaineXylodase', 'Xylotox', 'Ztlido']", 'syns_list': "['ALGRX 3268', 'ALGRX-3268', 'Anestacon'... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.453 | Q6 | What genes does Naldemedine Tosylate target when it's used to treat Constipation? | When used to treat Constipation, the drug Naldemedine Tosylate targets the gene OPRM1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%naldemedine tosylate%" OR LOWER(tradeNames_list) ... | [{'UUID': 'DrugTargetsIndication121923_text_763382', 'drugName': 'Naldemedine Tosylate', 'tradeNames_list': "['Symproic']", 'syns_list': "['Naldemedine tosilate', 'Naldemedine tosylate']", 'target': 'ENSG00000112038', 'approvedSymbol': 'OPRM1', 'approvedName': 'opioid receptor mu 1', 'mesh_heading': 'Constipation', 'ef... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.559 | Q6 | What genes does Paclitaxel target when it's used to treat neoplasm? | When used to treat neoplasm, the drug Paclitaxel targets the genes TUBB4B, TUBB1, TUBA3C, TUBA4A, TUBB3, TUBA1A, TUBB4A, TUBB8, TUBB, TUBA1B, TUBA1C, TUBA3E, TUBB2A, TUBB2B, and TUBB6. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%paclitaxel%" OR LOWER(tradeNames_list) LIKE "%pac... | [{'UUID': 'DrugTargetsIndication121923_text_2177', 'drugName': 'Paclitaxel', 'tradeNames_list': "['Abraxane', 'Pacitaxel', 'Paclitaxel', 'Paxene', 'Taxol', 'Taxol 100']", 'syns_list': "['(-)-paclitaxel', 'ABI-007', 'ABI-007 COMPONENT PACLITAXEL', 'BMS 181339-01BMS-181339-01', 'Capxol', 'Cyclopax', 'DHP 107', 'DHP-107',... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.181 | Q6 | What genes does Aripiprazole Lauroxil target when it's used to treat autism? | When used to treat autism, the drug Aripiprazole Lauroxil targets the genes DRD2, HTR2A, and HTR1A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%aripiprazole lauroxil%" OR LOWER(tradeNames_list)... | [{'UUID': 'DrugTargetsIndication121923_text_158027', 'drugName': 'Aripiprazole Lauroxil', 'tradeNames_list': "['Aristada', 'Aristada initio kit']", 'syns_list': "['ALKS 9072', 'ALKS-9070', 'ALKS-9072', 'Aripiprazole lauroxilAristada initio', 'RDC-3317', 'RDC3317']", 'target': 'ENSG00000149295', 'approvedSymbol': 'DRD2'... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.396 | Q6 | What genes does Famotidine target when it's used to treat duodenal ulcer? | When used to treat duodenal ulcer, the drug Famotidine targets the gene HRH2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%famotidine%" OR LOWER(tradeNames_list) LIKE "%fam... | [{'UUID': 'DrugTargetsIndication121923_text_1100337', 'drugName': 'Famotidine', 'tradeNames_list': "['Famotidine', 'Famotidine preservative freeFamotidine preservative free (pharmacy bulk)', 'Fluxid', 'PepcidPepcid ac', 'Pepcid preservative free', 'Pepcid rpd']", 'syns_list': "['Amfamox', 'Fadul', 'Famodil', 'Famosan',... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.584 | Q6 | What genes does Prednisone target when it's used to treat psoriasis? | When used to treat psoriasis, the drug Prednisone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%prednisone%" OR LOWER(tradeNames_list) LIKE "%pre... | [{'UUID': 'DrugTargetsIndication121923_text_218673', 'drugName': 'Prednisone', 'tradeNames_list': "['Cortan', 'Cortancyl', 'Decortisyl', 'Delta-dome', 'Deltasone', 'FernisoneLiquid pred', 'Lodotra', 'Meticorten', 'Orasone', 'Paracort', 'Prednicen-mPrednisone', 'Prednisone intensol', 'Rayos', 'Servisone', 'Sterapred']",... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.995 | Q6 | What genes does Selinexor target when it's used to treat glioblastoma multiforme? | Selinexor has not been approved by the FDA as a treatment for glioblastoma multiforme, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is XPO1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%selinexor%" OR LOWER(tradeNames_list) LIKE "%seli... | [{'UUID': 'DrugTargetsIndication121923_text_1193912', 'drugName': 'Selinexor', 'tradeNames_list': "['Xpovio']", 'syns_list': "['KPT-330', 'Selinexor']", 'target': 'ENSG00000082898', 'approvedSymbol': 'XPO1', 'approvedName': 'exportin 1', 'mesh_heading': 'Glioblastoma', 'efo_term': 'glioblastoma multiforme', 'yearOfFirs... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1707 | Q6 | What genes does Desoximetasone target when it's used to treat skin disease? | When used to treat skin disease, the drug Desoximetasone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%desoximetasone%" OR LOWER(tradeNames_list) LIKE "... | [{'UUID': 'DrugTargetsIndication121923_text_220821', 'drugName': 'Desoximetasone', 'tradeNames_list': "['Desoximetasone', 'Stiedex', 'Stiedex lp', 'Stiedex lpn', 'TopicortTopicort lp']", 'syns_list': "['A-41-304', 'A-41304', 'Desoximetasone', 'Desoxymethasone', 'HOE 304HOE-304', 'J83.644C', 'NSC-759189', 'R 2113', 'R-2... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1285 | Q6 | What genes does Zoledronic Acid target when it's used to treat osteoporosis? | When used to treat osteoporosis, the drug Zoledronic Acid targets the gene FDPS. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%zoledronic acid%" OR LOWER(tradeNames_list) LIKE ... | [{'UUID': 'DrugTargetsIndication121923_text_1099713', 'drugName': 'Zoledronic Acid', 'tradeNames_list': "['Aclasta', 'Reclast', 'Zerlinda', 'Zoledronic acid', 'Zometa']", 'syns_list': "['AK-156', 'Anhydrous zoledronic acid', 'CGP 42446', 'CGP-42446', 'CGP-42446ANSC-721517', 'Zoladrona acid mylan', 'Zoledronate', 'Zoled... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1645 | Q6 | What genes does Axitinib target when it's used to treat renal cell carcinoma? | When used to treat renal cell carcinoma, the drug Axitinib targets the genes KDR, FLT1, and FLT4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%axitinib%" OR LOWER(tradeNames_list) LIKE "%axiti... | [{'UUID': 'DrugTargetsIndication121923_text_689241', 'drugName': 'Axitinib', 'tradeNames_list': "['Inlyta']", 'syns_list': "['AG-013736', 'AG-13736', 'Axitinib', 'NSC-757441']", 'target': 'ENSG00000128052', 'approvedSymbol': 'KDR', 'approvedName': 'kinase insert domain receptor', 'mesh_heading': 'Carcinoma, Renal Cell'... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.886 | Q6 | What genes does Docetaxel target when it's used to treat cervical cancer? | Docetaxel has not been approved by the FDA as a treatment for cervical cancer, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are TUBB4B, TUBB1, TUBA3C, TUBA4A, TUBB3, TUBA1A, TUBB4A, TUBB8, TUBB, TUBA1B, TUBA1C, TUBA3E, TUBB2A, TUBB2B, and TUBB6. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%docetaxel%" OR LOWER(tradeNames_list) LIKE "%doce... | [{'UUID': 'DrugTargetsIndication121923_text_96037', 'drugName': 'Docetaxel', 'tradeNames_list': "['Docefrez', 'Docetaxel', 'Taxceus', 'Taxotere']", 'syns_list': "['Bind 014', 'CKD-810', 'Docetaxel', 'Docetaxel (as trihydrate)Docetaxel anhydrous', 'Docetaxel hydrate', 'Docetaxel trihydrateNSC-628503', 'RP 56976', 'RP-56... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.827 | Q6 | What genes does Calcipotriene target when it's used to treat radiodermatitis? | Calcipotriene has not been approved by the FDA as a treatment for radiodermatitis, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is VDR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%calcipotriene%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_823600', 'drugName': 'Calcipotriene', 'tradeNames_list': "['Calcipotriene', 'Dovobet', 'Dovonex', 'Enstilar', 'Sorilux', 'Xamiol']", 'syns_list': "['Calcipotriene', 'Calcipotriene hydrate', 'Calcipotriene monohydrateCalcipotriol', 'Calcipotriol anhydrous', 'Calcipotriol hydra... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1660 | Q6 | What genes does Fentanyl target when it's used to treat neoplasm? | When used to treat neoplasm, the drug Fentanyl targets the gene OPRM1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fentanyl%" OR LOWER(tradeNames_list) LIKE "%fenta... | [{'UUID': 'DrugTargetsIndication121923_text_786062', 'drugName': 'Fentanyl', 'tradeNames_list': "['Abstral', 'Actiq', 'Breakyl', 'Duragesic', 'Duragesic-100', 'Duragesic-12Duragesic-25', 'Duragesic-37', 'Duragesic-50', 'Duragesic-75', 'DurogesicDurogesic dtrans', 'Effentora', 'Fencino', 'Fentalis reservoirFentanyl-100'... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.972 | Q6 | What genes does Olaparib target when it's used to treat malignant epithelial tumor of ovary? | Olaparib has not been approved by the FDA as a treatment for malignant epithelial tumor of ovary, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are PARP2, PARP1, and PARP3. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%olaparib%" OR LOWER(tradeNames_list) LIKE "%olapa... | [{'UUID': 'DrugTargetsIndication121923_text_795369', 'drugName': 'Olaparib', 'tradeNames_list': "['Lynparza']", 'syns_list': "['AZ-2281', 'AZ2281', 'AZD-2281', 'AZD2281', 'KEYLYNK-010 COMPONENT OLAPARIBKU-0059436', 'KU-59436', 'NSC-747856', 'OLAPARIB COMPONENT OF KEYLYNK-010Olaparib']", 'target': 'ENSG00000129484', 'ap... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1049 | Q6 | What genes does Diazepam target when it's used to treat cerebral palsy? | When used to treat cerebral palsy, the drug Diazepam targets the genes GABRA1, GABRB2, GABRG2, GABRB3, GABRA4, GABRG3, GABRQ, GABRA3, GABRP, GABRD, GABRG1, GABRB1, GABRE, GABRA2, GABRA5, and GABRA6. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%diazepam%" OR LOWER(tradeNames_list) LIKE "%diaze... | [{'UUID': 'DrugTargetsIndication121923_text_960287', 'drugName': 'Diazepam', 'tradeNames_list': "['Alupram 10', 'Alupram 2', 'Alupram 5', 'Apozepam', 'Atensine', 'DialarDialar fte', 'Diastat', 'Diastat acudial', 'Diazepam', 'Diazepam intensolDizac', 'E-Pam', 'Paxel', 'Q-pam', 'Relanium', 'Scriptopam', 'SerenackSolis', ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.671 | Q6 | What genes does Amiodarone Hydrochloride target when it's used to treat ventricular fibrillation? | When used to treat ventricular fibrillation, the drug Amiodarone Hydrochloride targets the gene KCNH2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%amiodarone hydrochloride%" OR LOWER(tradeNames_li... | [{'UUID': 'DrugTargetsIndication121923_text_969594', 'drugName': 'Amiodarone Hydrochloride', 'tradeNames_list': "['Amidox', 'Amiodarone hydrochloride', 'Amyben', 'Cordarone', 'Cordarone xCordarone x 100', 'Cordarone x 200', 'Darmil', 'Nexterone', 'Pacerone']", 'syns_list': "['Amiodar', 'Amiodarone', 'Amiodarone hcl', '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.145 | Q6 | What genes does Irinotecan Hydrochloride target when it's used to treat lymphoma? | Irinotecan Hydrochloride has not been approved by the FDA as a treatment for lymphoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is TOP1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%irinotecan hydrochloride%" OR LOWER(tradeNames_li... | [{'UUID': 'DrugTargetsIndication121923_text_942044', 'drugName': 'Irinotecan Hydrochloride', 'tradeNames_list': "['Campto', 'Camptosar', 'Irinotecan hydrochloride', 'Onivyde']", 'syns_list': "['CPT-11', 'DQ-2805', 'Irinotecan hydrochlorideIrinotecan hydrochloride anhydrous', 'Irinotecan hydrochloride hydrateIrinotecan ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1518 | Q6 | What genes does Indacaterol Maleate target when it's used to treat emphysema? | When used to treat emphysema, the drug Indacaterol Maleate targets the gene ADRB2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%indacaterol maleate%" OR LOWER(tradeNames_list) L... | [{'UUID': 'DrugTargetsIndication121923_text_937188', 'drugName': 'Indacaterol Maleate', 'tradeNames_list': "['Arcapta neohaler', 'Onbrez breezhaler']", 'syns_list': "['Indacaterol (as maleate)', 'Indacaterol maleate', 'Indacterol maleateQAB-149-AFA', 'QAB149-AFA']", 'target': 'ENSG00000169252', 'approvedSymbol': 'ADRB2... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1999 | Q6 | What genes does Encorafenib target when it's used to treat cutaneous melanoma? | When used to treat cutaneous melanoma, the drug Encorafenib targets the gene BRAF. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%encorafenib%" OR LOWER(tradeNames_list) LIKE "%en... | [{'UUID': 'DrugTargetsIndication121923_text_752306', 'drugName': 'Encorafenib', 'tradeNames_list': "['Braftovi']", 'syns_list': "['Encorafenib', 'Lgx-818', 'Lgx818', 'NVP-LGX-818-NXA', 'NVP-LGX818NVP-LGX818-NXA']", 'target': 'ENSG00000157764', 'approvedSymbol': 'BRAF', 'approvedName': 'B-Raf proto-oncogene, serine/thre... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.871 | Q6 | What genes does Phentermine Hydrochloride target when it's used to treat obesity? | When used to treat obesity, the drug Phentermine Hydrochloride targets the gene SLC6A2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%phentermine hydrochloride%" OR LOWER(tradeNames_l... | [{'UUID': 'DrugTargetsIndication121923_text_434240', 'drugName': 'Phentermine Hydrochloride', 'tradeNames_list': "['Adipex-p', 'Fastin', 'Lomaira', 'Obestin-30', 'Oby-trim', 'Ona-mastPhentermine hydrochloride', 'Suprenza', 'Tora', 'Wilpo']", 'syns_list': "['NSC-44090', 'Phentermine hcl', 'Phentermine hydrochloridePhent... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.427 | Q6 | What genes does Omeprazole target when it's used to treat gastroesophageal reflux disease? | When used to treat gastroesophageal reflux disease, the drug Omeprazole targets the genes ATP4A and ATP4B. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%omeprazole%" OR LOWER(tradeNames_list) LIKE "%ome... | [{'UUID': 'DrugTargetsIndication121923_text_1098037', 'drugName': 'Omeprazole', 'tradeNames_list': "['Antra', 'Losec', 'Losec mups', 'Mezzopram', 'Mopral', 'Omeprazole', 'OmeranPrilosec', 'Zanprol']", 'syns_list': "['H 168/68', 'H-168/68', 'NSC-751450', 'NSC-759192', 'Omeprazole']", 'target': 'ENSG00000105675', 'approv... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.643 | Q6 | What genes does Ospemifene target when it's used to treat menopause? | When used to treat menopause, the drug Ospemifene targets the genes ESR1 and ESR2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ospemifene%" OR LOWER(tradeNames_list) LIKE "%osp... | [{'UUID': 'DrugTargetsIndication121923_text_823747', 'drugName': 'Ospemifene', 'tradeNames_list': "['Osphena', 'Senshio']", 'syns_list': "['(deaminohydroxy) toremifene', 'FC-1271', 'FC-1271A', 'OspemifeneTore iii']", 'target': 'ENSG00000091831', 'approvedSymbol': 'ESR1', 'approvedName': 'estrogen receptor 1', 'mesh_hea... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1408 | Q6 | What genes does Thalidomide target when it's used to treat brain stem neoplasm? | Thalidomide has not been approved by the FDA as a treatment for brain stem neoplasm, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are CRBN, DDB1, CUL4A, and RBX1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%thalidomide%" OR LOWER(tradeNames_list) LIKE "%th... | [{'UUID': 'DrugTargetsIndication121923_text_1105086', 'drugName': 'Thalidomide', 'tradeNames_list': "['Talidex', 'Thalomid']", 'syns_list': "['.alpha.-phthalimidoglutarimide', 'Celgene', 'Contergan', 'Distaval', 'K-17Myrin', 'N-phthalylglutamic acid imide', 'NSC-527179', 'NSC-66847Neurosedyn', 'Pantosediv', 'Pharmion',... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.806 | Q6 | What genes does Amisulpride target when it's used to treat Nausea and vomiting? | When used to treat Nausea and vomiting, the drug Amisulpride targets the genes HTR2C, DRD2, DRD3, HTR2A, HTR3A, HTR1A, HTR3E, HTR3B, HTR3D, HTR3C, HTR4, HTR1F, HTR2B, HTR1B, HTR1D, HTR1E, HTR7, HTR6, and HTR5A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%amisulpride%" OR LOWER(tradeNames_list) LIKE "%am... | [{'UUID': 'DrugTargetsIndication121923_text_152005', 'drugName': 'Amisulpride', 'tradeNames_list': "['Barhemsys', 'Solian', 'Solian 100', 'Solian 200', 'Solian 400', 'Solian 50']", 'syns_list': "['APD-421', 'APD421', 'Aminosultopride', 'Amisulpride', 'DAN-2163', 'DenibanNSC-760085', 'Socian', 'Sulamid']", 'target': 'EN... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1067 | Q6 | What genes does Propofol target when it's used to treat septic shock? | Propofol has not been approved by the FDA as a treatment for septic shock, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are GABRA1, GABRB2, GABRG2, GABRB3, GABRA4, GABRG3, GABRQ, GABRA3, GABRP, GABRD, GABRG1, GABRB1, GABRE, GABRA2, GABRA5, and GABRA6. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%propofol%" OR LOWER(tradeNames_list) LIKE "%propo... | [{'UUID': 'DrugTargetsIndication121923_text_965033', 'drugName': 'Propofol', 'tradeNames_list': "['Diprivan', 'Disoprivan', 'Propofol', 'Rapinovet']", 'syns_list': "['Disoprofol', 'Fresofol', 'ICI 35,868', 'ICI 35-868', 'ICI-35868', 'ICI35,868Lipuro', 'NSC-5105', 'Phenol, 2,6-bis(1-methylethyl)', 'Propofol']", 'target'... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.622 | Q6 | What genes does Plerixafor target when it's used to treat childhood cancer? | When used to treat childhood cancer, the drug Plerixafor targets the gene CXCR4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%plerixafor%" OR LOWER(tradeNames_list) LIKE "%ple... | [{'UUID': 'DrugTargetsIndication121923_text_1103213', 'drugName': 'Plerixafor', 'tradeNames_list': "['Mozobil']", 'syns_list': "['AMD 3100', 'AMD3100', 'JM 3100', 'Plerixafor', 'Plerixafor hydrochloridePlerixafor octahydrochloride', 'SID 791']", 'target': 'ENSG00000121966', 'approvedSymbol': 'CXCR4', 'approvedName': 'C... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.298 | Q6 | What genes does Macitentan target when it's used to treat ulcer disease? | Macitentan has not been approved by the FDA as a treatment for ulcer disease, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are EDNRA and EDNRB. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%macitentan%" OR LOWER(tradeNames_list) LIKE "%mac... | [{'UUID': 'DrugTargetsIndication121923_text_1083997', 'drugName': 'Macitentan', 'tradeNames_list': "['Opsumit']", 'syns_list': "['ACT 064992', 'ACT-064992', 'Macitentan']", 'target': 'ENSG00000136160', 'approvedSymbol': 'EDNRB', 'approvedName': 'endothelin receptor type B', 'mesh_heading': 'Ulcer', 'efo_term': 'ulcer d... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.912 | Q6 | What genes does Pomalidomide target when it's used to treat Kaposi's sarcoma? | Pomalidomide has not been approved by the FDA as a treatment for Kaposi's sarcoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are CRBN, DDB1, CUL4A, and RBX1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%pomalidomide%" OR LOWER(tradeNames_list) LIKE "%p... | [{'UUID': 'DrugTargetsIndication121923_text_1141310', 'drugName': 'Pomalidomide', 'tradeNames_list': "['Imnovid', 'Pomalyst']", 'syns_list': "['Actimid', 'CC-4047', 'IMID 3', 'IMID-3', 'Pomalidomide']", 'target': 'ENSG00000113851', 'approvedSymbol': 'CRBN', 'approvedName': 'cereblon', 'mesh_heading': 'Sarcoma, Kaposi',... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.917 | Q6 | What genes does Aspirin target when it's used to treat muscle cramp? | When used to treat muscle cramp, the drug Aspirin targets the genes PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%aspirin%" OR LOWER(tradeNames_list) LIKE "%aspiri... | [{'UUID': 'DrugTargetsIndication121923_text_834439', 'drugName': 'Aspirin', 'tradeNames_list': "['8-hour bayer', 'Acetosalic Acid', 'Acetylsalic acidAcetylsalicylic Acid', 'Alka rapid', 'Anadin all night', 'Angettes 75Aspirin', 'Aspro clr', 'Bayer extra strength aspirin for migraine painDanamep', 'Disprin cv', 'Disprin... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1903 | Q6 | What genes does Ondansetron target when it's used to treat cancer? | When used to treat cancer, the drug Ondansetron targets the gene HTR3A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ondansetron%" OR LOWER(tradeNames_list) LIKE "%on... | [{'UUID': 'DrugTargetsIndication121923_text_205979', 'drugName': 'Ondansetron', 'tradeNames_list': "['Ondansetron', 'Zofran', 'Zofran odt', 'Zuplenz']", 'syns_list': "['A04AA01', 'Desmethylondansetron', 'EUR-1025', 'GR-38032', 'GR-38032FNSC-757870', 'Ondansetron', 'Zofran']", 'target': 'ENSG00000166736', 'approvedSymbo... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.91 | Q6 | What genes does Levodopa target when it's used to treat nicotine dependence? | Levodopa has not been approved by the FDA as a treatment for nicotine dependence, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is DRD3. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%levodopa%" OR LOWER(tradeNames_list) LIKE "%levod... | [{'UUID': 'DrugTargetsIndication121923_text_204964', 'drugName': 'Levodopa', 'tradeNames_list': "['Bendopa', 'Brocadopa', 'Dopar', 'Inbrija', 'Larodopa']", 'syns_list': "['Bendopa', 'Cvt-301', 'Levodopa', 'Levodopum', 'NSC-118381', 'V-1512']", 'target': 'ENSG00000151577', 'approvedSymbol': 'DRD3', 'approvedName': 'dopa... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.42 | Q6 | What genes does Celecoxib target when it's used to treat Alzheimer disease? | Celecoxib has not been approved by the FDA as a treatment for Alzheimer disease, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is PTGS2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%celecoxib%" OR LOWER(tradeNames_list) LIKE "%cele... | [{'UUID': 'DrugTargetsIndication121923_text_833484', 'drugName': 'Celecoxib', 'tradeNames_list': "['Celebra', 'Celebrex', 'Celecoxib', 'Elyxyb', 'Onsenal']", 'syns_list': "['Celecoxib', 'DFN-15', 'DFN15', 'NSC-719627', 'NSC-758624', 'SC-58635']", 'target': 'ENSG00000073756', 'approvedSymbol': 'PTGS2', 'approvedName': '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
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