uuid stringlengths 4 8 | template_uuid stringclasses 40
values | question stringlengths 13 193 | answer stringlengths 29 2.2k | benchmark_query stringlengths 133 622 | execution_results stringlengths 2 1.14M | query_type stringclasses 2
values | sql_category stringclasses 26
values | bio_category stringclasses 14
values |
|---|---|---|---|---|---|---|---|---|
Q6.1803 | Q6 | What genes does Propofol target when it's used to treat obesity? | Propofol has not been approved by the FDA as a treatment for obesity, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are GABRA1, GABRB2, GABRG2, GABRB3, GABRA4, GABRG3, GABRQ, GABRA3, GABRP, GABRD, GABRG1, GABRB1, GABRE, GABRA2, GABRA5, and GABRA6. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%propofol%" OR LOWER(tradeNames_list) LIKE "%propo... | [{'UUID': 'DrugTargetsIndication121923_text_966203', 'drugName': 'Propofol', 'tradeNames_list': "['Diprivan', 'Disoprivan', 'Propofol', 'Rapinovet']", 'syns_list': "['Disoprofol', 'Fresofol', 'ICI 35,868', 'ICI 35-868', 'ICI-35868', 'ICI35,868Lipuro', 'NSC-5105', 'Phenol, 2,6-bis(1-methylethyl)', 'Propofol']", 'target'... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1934 | Q6 | What genes does Epinephrine target when it's used to treat glaucoma? | When used to treat glaucoma, the drug Epinephrine targets the genes ADRA1A, ADRB2, ADRB1, ADRB3, ADRA1D, ADRA1B, ADRA2A, ADRA2C, and ADRA2B. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%epinephrine%" OR LOWER(tradeNames_list) LIKE "%ep... | [{'UUID': 'DrugTargetsIndication121923_text_361089', 'drugName': 'Epinephrine', 'tradeNames_list': "['Adren co', 'Adrenaclick', 'Adrenalin', 'Ana-Kit', 'Ana-guard', 'AnapenAnaphylactic shock drug kit', 'Asma-vydrin', 'Asthmahaler', 'Auvi-qBronkaid mist', 'Brovon', 'Emerade', 'Epi e z pen jr', 'EpinephrineEpinephrine (c... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.134 | Q6 | What genes does Levonorgestrel target when it's used to treat Menorrhagia? | When used to treat Menorrhagia, the drug Levonorgestrel targets the gene PGR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%levonorgestrel%" OR LOWER(tradeNames_list) LIKE "... | [{'UUID': 'DrugTargetsIndication121923_text_940260', 'drugName': 'Levonorgestrel', 'tradeNames_list': "['Athentia next', 'Emerres', 'Emerres una', 'Ezinelle', 'Fallback soloHer style', 'Isteranda', 'Jadelle', 'Jaydess', 'Kyleena', 'LevonelleLevonelle one step', 'Levonelle-2', 'Levonorgestrel', 'Levosert', 'LilettaMicro... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1566 | Q6 | What genes does Celecoxib target when it's used to treat rheumatoid arthritis? | When used to treat rheumatoid arthritis, the drug Celecoxib targets the gene PTGS2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%celecoxib%" OR LOWER(tradeNames_list) LIKE "%cele... | [{'UUID': 'DrugTargetsIndication121923_text_833494', 'drugName': 'Celecoxib', 'tradeNames_list': "['Celebra', 'Celebrex', 'Celecoxib', 'Elyxyb', 'Onsenal']", 'syns_list': "['Celecoxib', 'DFN-15', 'DFN15', 'NSC-719627', 'NSC-758624', 'SC-58635']", 'target': 'ENSG00000073756', 'approvedSymbol': 'PTGS2', 'approvedName': '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.977 | Q6 | What genes does Dexamethasone target when it's used to treat cystoid macular edema? | When used to treat cystoid macular edema, the drug Dexamethasone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dexamethasone%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_227806', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1070 | Q6 | What genes does Lesinurad target when it's used to treat hyperuricemia? | When used to treat hyperuricemia, the drug Lesinurad targets the gene SLC22A12. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lesinurad%" OR LOWER(tradeNames_list) LIKE "%lesi... | [{'UUID': 'DrugTargetsIndication121923_text_1096803', 'drugName': 'Lesinurad', 'tradeNames_list': "['Zurampic']", 'syns_list': "['Lesinurad', 'RDEA 594', 'RDEA-594', 'RDEA594']", 'target': 'ENSG00000197891', 'approvedSymbol': 'SLC22A12', 'approvedName': 'solute carrier family 22 member 12', 'mesh_heading': 'Hyperuricem... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1856 | Q6 | What genes does Azacitidine target when it's used to treat anemia? | When used to treat anemia, the drug Azacitidine targets the genes DNMT1 and DNMT3A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%azacitidine%" OR LOWER(tradeNames_list) LIKE "%az... | [{'UUID': 'DrugTargetsIndication121923_text_1192044', 'drugName': 'Azacitidine', 'tradeNames_list': "['Azacitidine', 'Onureg', 'Vidaza']", 'syns_list': "['5-azacitidine', 'Azacitidine', 'Ladakamycin', 'NSC-102816', 'U-18,496U-18496', 'Vidaza']", 'target': 'ENSG00000119772', 'approvedSymbol': 'DNMT3A', 'approvedName': '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1346 | Q6 | What genes does Methotrexate target when it's used to treat non-Hodgkins lymphoma? | When used to treat non-Hodgkins lymphoma, the drug Methotrexate targets the gene DHFR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%methotrexate%" OR LOWER(tradeNames_list) LIKE "%m... | [{'UUID': 'DrugTargetsIndication121923_text_1057594', 'drugName': 'Methotrexate', 'tradeNames_list': "['Amethopterin', 'Ebetrex', 'Emtexate high-pot', 'Emtexate pf', 'FolexMaxtrex', 'Methotrexate', 'Metoject', 'Mexate', 'Otrexup', 'Otrexup pfsRasuvo', 'Reditrex', 'Rheumatrex', 'Trexall', 'Zlatal']", 'syns_list': "['(r)... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1831 | Q6 | What genes does Palonosetron Hydrochloride target when it's used to treat Nausea? | When used to treat Nausea, the drug Palonosetron Hydrochloride targets the gene HTR3A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%palonosetron hydrochloride%" OR LOWER(tradeNames_... | [{'UUID': 'DrugTargetsIndication121923_text_205497', 'drugName': 'Palonosetron Hydrochloride', 'tradeNames_list': "['Aloxi', 'Palonosetron hydrochloride']", 'syns_list': "['Palonocetron hydrochloride', 'Palonosetron (as hydrochloride)Palonosetron hcl', 'Palonosetron hydrochloride', 'RS-25259-197']", 'target': 'ENSG0000... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.167 | Q6 | What genes does Belinostat target when it's used to treat non-small cell lung carcinoma? | Belinostat has not been approved by the FDA as a treatment for non-small cell lung carcinoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are HDAC1, HDAC3, HDAC6, HDAC2, HDAC5, HDAC7, HDAC8, HDAC11, HDAC4, HDAC9, and HDAC10. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%belinostat%" OR LOWER(tradeNames_list) LIKE "%bel... | [{'UUID': 'DrugTargetsIndication121923_text_1079968', 'drugName': 'Belinostat', 'tradeNames_list': "['Beleodaq']", 'syns_list': "['Belinostat', 'NSC-726630', 'NSC726630', 'PX-105684', 'PXD-101', 'PXD101']", 'target': 'ENSG00000094631', 'approvedSymbol': 'HDAC6', 'approvedName': 'histone deacetylase 6', 'mesh_heading': ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.731 | Q6 | What genes does Cannabidiol target when it's used to treat Lennox-Gastaut syndrome? | When used to treat Lennox-Gastaut syndrome, the drug Cannabidiol targets the gene CNR1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%cannabidiol%" OR LOWER(tradeNames_list) LIKE "%ca... | [{'UUID': 'DrugTargetsIndication121923_text_1073764', 'drugName': 'Cannabidiol', 'tradeNames_list': "['Epidiolex']", 'syns_list': "['(-)-cannabidiol', '(-)-cbd', '(-)-trans-cannabidiol.delta.1(2)-trans-cannabidiol', 'BTX-1204', 'BTX-1503', 'CBD', 'CannabidiolCannabidiol solution', 'Cardiolrx', 'GWP-42003', 'GWP-42003-P... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.294 | Q6 | What genes does Panobinostat target when it's used to treat myelodysplastic syndrome? | Panobinostat has not been approved by the FDA as a treatment for myelodysplastic syndrome, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are HDAC1, HDAC3, HDAC6, HDAC2, HDAC5, HDAC7, HDAC8, HDAC11, HDAC4, HDAC9, and HDAC10. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%panobinostat%" OR LOWER(tradeNames_list) LIKE "%p... | [{'UUID': 'DrugTargetsIndication121923_text_1080908', 'drugName': 'Panobinostat', 'tradeNames_list': "['Farydak']", 'syns_list': "['LBH-589', 'LBH589', 'Panobinostat', 'Panobinostat hydrate']", 'target': 'ENSG00000116478', 'approvedSymbol': 'HDAC1', 'approvedName': 'histone deacetylase 1', 'mesh_heading': 'Myelodysplas... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1142 | Q6 | What genes does Cabozantinib S-Malate target when it's used to treat papillary renal cell carcinoma? | When used to treat papillary renal cell carcinoma, the drug Cabozantinib S-Malate targets the genes KDR and MET. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%cabozantinib s-malate%" OR LOWER(tradeNames_list)... | [{'UUID': 'DrugTargetsIndication121923_text_669672', 'drugName': 'Cabozantinib S-Malate', 'tradeNames_list': "['Cabometyx', 'Cometriq']", 'syns_list': "['BMS-907351', 'Cabozantinib malate', 'Cabozantinib s-malate', 'XL-184XL184']", 'target': 'ENSG00000128052', 'approvedSymbol': 'KDR', 'approvedName': 'kinase insert dom... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1536 | Q6 | What genes does Buprenorphine target when it's used to treat Chronic pain? | When used to treat Chronic pain, the drug Buprenorphine targets the genes OPRM1 and OPRK1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%buprenorphine%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_764193', 'drugName': 'Buprenorphine', 'tradeNames_list': "['Bupeaze', 'Buplast', 'Butec', 'Butrans', 'Hapoctasin', 'Panitaz', 'PrenotrixReletrans', 'Sevodyne', 'Sublocade', 'Temgesic', 'Tephine', 'Transtec']", 'syns_list': "['ALKS-5461 COMPONENT BUPRENORPHINE', 'Brixadi', 'Bu... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1897 | Q6 | What genes does Dexamethasone target when it's used to treat hemorrhoid? | When used to treat hemorrhoid, the drug Dexamethasone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dexamethasone%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_227781', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1006 | Q6 | What genes does Lidocaine target when it's used to treat cardiac arrhythmia? | When used to treat cardiac arrhythmia, the drug Lidocaine targets the genes SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lidocaine%" OR LOWER(tradeNames_list) LIKE "%lido... | [{'UUID': 'DrugTargetsIndication121923_text_638360', 'drugName': 'Lidocaine', 'tradeNames_list': "['Alphacaine', 'Anestacon', 'Dentipatch', 'Lidocaine', 'LidodermLignocaine Hcl', 'Lignostab', 'Lmx 4', 'Oraqix', 'Vagisil', 'XylocaineXylodase', 'Xylotox', 'Ztlido']", 'syns_list': "['ALGRX 3268', 'ALGRX-3268', 'Anestacon'... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1421 | Q6 | What genes does Celecoxib target when it's used to treat stroke? | When used to treat stroke, the drug Celecoxib targets the gene PTGS2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%celecoxib%" OR LOWER(tradeNames_list) LIKE "%cele... | [{'UUID': 'DrugTargetsIndication121923_text_833495', 'drugName': 'Celecoxib', 'tradeNames_list': "['Celebra', 'Celebrex', 'Celecoxib', 'Elyxyb', 'Onsenal']", 'syns_list': "['Celecoxib', 'DFN-15', 'DFN15', 'NSC-719627', 'NSC-758624', 'SC-58635']", 'target': 'ENSG00000073756', 'approvedSymbol': 'PTGS2', 'approvedName': '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.785 | Q6 | What genes does Doxycycline target when it's used to treat pneumonia? | When used to treat pneumonia, the drug Doxycycline targets the genes MMP7, MMP1, MMP13, and MMP8. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%doxycycline%" OR LOWER(tradeNames_list) LIKE "%do... | [{'UUID': 'DrugTargetsIndication121923_text_1038221', 'drugName': 'Doxycycline', 'tradeNames_list': "['Doxychel', 'Doxycycline', 'Monodox', 'Oracea', 'Vibramycin']", 'syns_list': "['Doxirobe', 'Doxycycline', 'Doxycycline monohydrate', 'Doxylin', 'GS-3065Supracyclin', 'Xyrosa']", 'target': 'ENSG00000137673', 'approvedSy... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.846 | Q6 | What genes does Mometasone Furoate target when it's used to treat Nasal congestion? | When used to treat Nasal congestion, the drug Mometasone Furoate targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%mometasone furoate%" OR LOWER(tradeNames_list) LI... | [{'UUID': 'DrugTargetsIndication121923_text_242036', 'drugName': 'Mometasone Furoate', 'tradeNames_list': "['Asmanex', 'Asmanex hfa', 'Asmanex twisthaler', 'EloconMometasone furoate', 'Nasonex', 'Nasonex 24hr allergy', 'Sinuva']", 'syns_list': "['LAS-41002', 'LAS41002', 'LYR-210', 'LYR210', 'Lyr-210', 'MometasoneMometa... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.352 | Q6 | What genes does Plerixafor target when it's used to treat non-Hodgkins lymphoma? | When used to treat non-Hodgkins lymphoma, the drug Plerixafor targets the gene CXCR4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%plerixafor%" OR LOWER(tradeNames_list) LIKE "%ple... | [{'UUID': 'DrugTargetsIndication121923_text_1103212', 'drugName': 'Plerixafor', 'tradeNames_list': "['Mozobil']", 'syns_list': "['AMD 3100', 'AMD3100', 'JM 3100', 'Plerixafor', 'Plerixafor hydrochloridePlerixafor octahydrochloride', 'SID 791']", 'target': 'ENSG00000121966', 'approvedSymbol': 'CXCR4', 'approvedName': 'C... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1945 | Q6 | What genes does Ripretinib target when it's used to treat gastrointestinal stromal tumor? | When used to treat gastrointestinal stromal tumor, the drug Ripretinib targets the genes KIT and PDGFRA. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ripretinib%" OR LOWER(tradeNames_list) LIKE "%rip... | [{'UUID': 'DrugTargetsIndication121923_text_933996', 'drugName': 'Ripretinib', 'tradeNames_list': "['Qinlock']", 'syns_list': "['DCC-2618', 'Dcc-2618', 'Ripretinib']", 'target': 'ENSG00000157404', 'approvedSymbol': 'KIT', 'approvedName': 'KIT proto-oncogene, receptor tyrosine kinase', 'mesh_heading': 'Gastrointestinal ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.577 | Q6 | What genes does Bimatoprost target when it's used to treat ocular hypertension? | When used to treat ocular hypertension, the drug Bimatoprost targets the gene PTGFR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%bimatoprost%" OR LOWER(tradeNames_list) LIKE "%bi... | [{'UUID': 'DrugTargetsIndication121923_text_1149176', 'drugName': 'Bimatoprost', 'tradeNames_list': "['Bimatoprost', 'Durysta', 'Latisse', 'Lumigan']", 'syns_list': "['AGN 192024', 'AGN-192024', 'Bimatoprost', 'Prostamide']", 'target': 'ENSG00000122420', 'approvedSymbol': 'PTGFR', 'approvedName': 'prostaglandin F recep... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1923 | Q6 | What genes does Fluorouracil target when it's used to treat head and neck malignant neoplasia? | Fluorouracil has not been approved by the FDA as a treatment for head and neck malignant neoplasia, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is TYMS. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fluorouracil%" OR LOWER(tradeNames_list) LIKE "%f... | [{'UUID': 'DrugTargetsIndication121923_text_919430', 'drugName': 'Fluorouracil', 'tradeNames_list': "['5.f.u.', 'Accusite', 'Actikerall', 'Adrucil', 'Carac', 'Efudex', 'EfudixFluoro-uracil roche', 'Fluoroplex', 'Fluorouracil', 'Tolak']", 'syns_list': "['5 FU', '5-FU', '5-Fluorouracil', '5-fluoruracil', 'FluorouracilFlu... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1888 | Q6 | What genes does Modafinil target when it's used to treat Parkinson disease? | Modafinil has not been approved by the FDA as a treatment for Parkinson disease, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is SLC6A3. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%modafinil%" OR LOWER(tradeNames_list) LIKE "%moda... | [{'UUID': 'DrugTargetsIndication121923_text_939422', 'drugName': 'Modafinil', 'tradeNames_list': "['Modafinil', 'Provigil']", 'syns_list': "['CEP 1538', 'CEP-1538', 'CRC-40476', 'CRL 40476', 'CRL-40476', 'DEP-1538Modafinil', 'Modafinil civ', 'Modaphonil', 'Modiodal', 'NSC-751178NSC-759110', 'THN-102 COMPONENT MODAFINIL... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1470 | Q6 | What genes does Zoledronic Acid target when it's used to treat metastasis? | When used to treat metastasis, the drug Zoledronic Acid targets the gene FDPS. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%zoledronic acid%" OR LOWER(tradeNames_list) LIKE ... | [{'UUID': 'DrugTargetsIndication121923_text_1099717', 'drugName': 'Zoledronic Acid', 'tradeNames_list': "['Aclasta', 'Reclast', 'Zerlinda', 'Zoledronic acid', 'Zometa']", 'syns_list': "['AK-156', 'Anhydrous zoledronic acid', 'CGP 42446', 'CGP-42446', 'CGP-42446ANSC-721517', 'Zoladrona acid mylan', 'Zoledronate', 'Zoled... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1818 | Q6 | What genes does Testosterone target when it's used to treat hypogonadotropic hypogonadism? | When used to treat hypogonadotropic hypogonadism, the drug Testosterone targets the gene AR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%testosterone%" OR LOWER(tradeNames_list) LIKE "%t... | [{'UUID': 'DrugTargetsIndication121923_text_921410', 'drugName': 'Testosterone Enanthate', 'tradeNames_list': "['Delatestryl', 'Primoteston depot', 'Testosterone enanthateXyosted (autoinjector)']", 'syns_list': "['Androtardyl', 'NSC-17591', 'Testosterone enantateTestosterone enanthate', 'Testosterone enanthate ciiiTest... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1317 | Q6 | What genes does Elagolix Sodium target when it's used to treat endometriosis? | When used to treat endometriosis, the drug Elagolix Sodium targets the gene GNRHR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%elagolix sodium%" OR LOWER(tradeNames_list) LIKE ... | [{'UUID': 'DrugTargetsIndication121923_text_1097301', 'drugName': 'Elagolix Sodium', 'tradeNames_list': "['Orilissa']", 'syns_list': "['Elagolix sodium', 'Elagolix sodium salt', 'NBI-56418 NA', 'NBI-56418-NAOrlissa']", 'target': 'ENSG00000109163', 'approvedSymbol': 'GNRHR', 'approvedName': 'gonadotropin releasing hormo... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1501 | Q6 | What genes does Simvastatin target when it's used to treat small cell lung carcinoma? | Simvastatin has not been approved by the FDA as a treatment for small cell lung carcinoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is HMGCR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%simvastatin%" OR LOWER(tradeNames_list) LIKE "%si... | [{'UUID': 'DrugTargetsIndication121923_text_1103937', 'drugName': 'Simvastatin', 'tradeNames_list': "['Flolipid', 'Lacersa', 'Ranzolont', 'Simvador', 'Simvastatin', 'ZocorZocor heart-pro']", 'syns_list': "['C10AA01', 'MK-0733', 'MK-733', 'NSC-758706', 'SimvastatinSimvastatin hydroxy acid', 'Synvinolin']", 'target': 'EN... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.464 | Q6 | What genes does Triamcinolone Acetonide target when it's used to treat injury? | When used to treat injury, the drug Triamcinolone Acetonide targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%triamcinolone acetonide%" OR LOWER(tradeNames_lis... | [{'UUID': 'DrugTargetsIndication121923_text_222003', 'drugName': 'Triamcinolone Acetonide', 'tradeNames_list': "['Adcortyl', 'Adcortyl in orabase', 'Allernaze', 'Aristocort', 'Aristocort aAristogel', 'Audicort', 'Aureocort', 'Azmacort', 'Flutex', 'Gppe ear dps capGppe ear oint', 'Kenacort', 'Kenalog', 'Kenalog in oraba... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.381 | Q6 | What genes does Axitinib target when it's used to treat cancer? | When used to treat cancer, the drug Axitinib targets the genes KDR, FLT1, and FLT4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%axitinib%" OR LOWER(tradeNames_list) LIKE "%axiti... | [{'UUID': 'DrugTargetsIndication121923_text_689447', 'drugName': 'Axitinib', 'tradeNames_list': "['Inlyta']", 'syns_list': "['AG-013736', 'AG-13736', 'Axitinib', 'NSC-757441']", 'target': 'ENSG00000128052', 'approvedSymbol': 'KDR', 'approvedName': 'kinase insert domain receptor', 'mesh_heading': 'Neoplasms', 'efo_term'... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1344 | Q6 | What genes does Fentanyl target when it's used to treat chronic kidney disease? | Fentanyl has not been approved by the FDA as a treatment for chronic kidney disease, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is OPRM1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fentanyl%" OR LOWER(tradeNames_list) LIKE "%fenta... | [{'UUID': 'DrugTargetsIndication121923_text_785899', 'drugName': 'Fentanyl', 'tradeNames_list': "['Abstral', 'Actiq', 'Breakyl', 'Duragesic', 'Duragesic-100', 'Duragesic-12Duragesic-25', 'Duragesic-37', 'Duragesic-50', 'Duragesic-75', 'DurogesicDurogesic dtrans', 'Effentora', 'Fencino', 'Fentalis reservoirFentanyl-100'... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.337 | Q6 | What genes does Methotrexate target when it's used to treat juvenile idiopathic arthritis? | When used to treat juvenile idiopathic arthritis, the drug Methotrexate targets the gene DHFR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%methotrexate%" OR LOWER(tradeNames_list) LIKE "%m... | [{'UUID': 'DrugTargetsIndication121923_text_1057590', 'drugName': 'Methotrexate', 'tradeNames_list': "['Amethopterin', 'Ebetrex', 'Emtexate high-pot', 'Emtexate pf', 'FolexMaxtrex', 'Methotrexate', 'Metoject', 'Mexate', 'Otrexup', 'Otrexup pfsRasuvo', 'Reditrex', 'Rheumatrex', 'Trexall', 'Zlatal']", 'syns_list': "['(r)... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1284 | Q6 | What genes does Teriparatide target when it's used to treat Back pain? | Teriparatide has not been approved by the FDA as a treatment for Back pain, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is PTH1R. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%teriparatide%" OR LOWER(tradeNames_list) LIKE "%t... | [{'UUID': 'DrugTargetsIndication121923_text_1025267', 'drugName': 'Teriparatide', 'tradeNames_list': "['Bonsity', 'Forsteo', 'Forteo']", 'syns_list': "['(1-34)-human parathyroid hormone', '1-34-human pthHuman parathyroid hormone 1-34', 'LY 333334', 'LY-333334', 'LY333334Pth (1-34)', 'Teriparatide', 'Teriparatide rdnaTe... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1762 | Q6 | What genes does Leuprolide Acetate target when it's used to treat precocious puberty? | When used to treat precocious puberty, the drug Leuprolide Acetate targets the gene GNRHR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%leuprolide acetate%" OR LOWER(tradeNames_list) LI... | [{'UUID': 'DrugTargetsIndication121923_text_1097030', 'drugName': 'Leuprolide Acetate', 'tradeNames_list': "['Carcinil', 'Eligard', 'Eligard kit', 'Fensolvi kit', 'Leuprolide acetateLeuprorelin', 'Lupron', 'Lupron Depot Ped', 'Lupron depotLupron depot-ped', 'Lupron depot-ped kit', 'Lutrate depot kit', 'Viadur']", 'syns... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1459 | Q6 | What genes does Latanoprost target when it's used to treat ocular hypertension? | When used to treat ocular hypertension, the drug Latanoprost targets the gene PTGFR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%latanoprost%" OR LOWER(tradeNames_list) LIKE "%la... | [{'UUID': 'DrugTargetsIndication121923_text_1149125', 'drugName': 'Latanoprost', 'tradeNames_list': "['Latanoprost', 'Monopost', 'Xalatan', 'Xelpros']", 'syns_list': "['Latanoprost', 'Latanoprost (isopropyl ester)', 'PHXA-41', 'PHXA41', 'T-2345T2345', 'XA-41', 'XA41']", 'target': 'ENSG00000122420', 'approvedSymbol': 'P... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.823 | Q6 | What genes does Nimodipine target when it's used to treat schizophrenia? | Nimodipine has not been approved by the FDA as a treatment for schizophrenia, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are CACNA1C, CACNA1S, CACNA1D, CACNA1F, and NR3C2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%nimodipine%" OR LOWER(tradeNames_list) LIKE "%nim... | [{'UUID': 'DrugTargetsIndication121923_text_1043394', 'drugName': 'Nimodipine', 'tradeNames_list': "['Nimodipine', 'Nimotop', 'Nymalize']", 'syns_list': "['Admon', 'BAY E 9736', 'BAY-E-9736', 'NSC-758476', 'Nemotan', 'NimodipineNimodipine ap', 'Periplum']", 'target': 'ENSG00000151067', 'approvedSymbol': 'CACNA1C', 'app... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1114 | Q6 | What genes does Cannabidiol target when it's used to treat Seizure? | When used to treat Seizure, the drug Cannabidiol targets the gene CNR1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%cannabidiol%" OR LOWER(tradeNames_list) LIKE "%ca... | [{'UUID': 'DrugTargetsIndication121923_text_1073761', 'drugName': 'Cannabidiol', 'tradeNames_list': "['Epidiolex']", 'syns_list': "['(-)-cannabidiol', '(-)-cbd', '(-)-trans-cannabidiol.delta.1(2)-trans-cannabidiol', 'BTX-1204', 'BTX-1503', 'CBD', 'CannabidiolCannabidiol solution', 'Cardiolrx', 'GWP-42003', 'GWP-42003-P... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1524 | Q6 | What genes does Progesterone target when it's used to treat hemorrhage? | When used to treat hemorrhage, the drug Progesterone targets the gene PGR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%progesterone%" OR LOWER(tradeNames_list) LIKE "%p... | [{'UUID': 'DrugTargetsIndication121923_text_940054', 'drugName': 'Progesterone', 'tradeNames_list': "['Crinone', 'Cyclogest', 'Endometrin', 'Gesterol', 'Lutigest', 'MilprosaProchieve', 'Progesta-care', 'Progestasert', 'Progesterone', 'ProgestinPrometrium', 'Regumate', 'Serenity for women', 'Syngestrone', 'Utrogestan']"... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1941 | Q6 | What genes does Ibuprofen target when it's used to treat HIV infection? | Ibuprofen has not been approved by the FDA as a treatment for HIV infection, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ibuprofen%" OR LOWER(tradeNames_list) LIKE "%ibup... | [{'UUID': 'DrugTargetsIndication121923_text_840137', 'drugName': 'Ibuprofen', 'tradeNames_list': '[\'Aches-n-pain\', \'Advil\', \'Advil liqui-gels\', \'Advil migraine liqui-gelsAnadin joint pain\', \'Anadin liquifast\', \'Anadin period pain reliefAnadin ultra\', \'Apsifen\', \'Apsifen-f\', \'Arthrofen 200\', \'Arthrofe... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1616 | Q6 | What genes does Venetoclax target when it's used to treat non-small cell lung carcinoma? | Venetoclax has not been approved by the FDA as a treatment for non-small cell lung carcinoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is BCL2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%venetoclax%" OR LOWER(tradeNames_list) LIKE "%ven... | [{'UUID': 'DrugTargetsIndication121923_text_989851', 'drugName': 'Venetoclax', 'tradeNames_list': "['Venclexta']", 'syns_list': "['ABT-199', 'GDC-0199', 'RG-7601', 'RG7601', 'Venetoclax']", 'target': 'ENSG00000171791', 'approvedSymbol': 'BCL2', 'approvedName': 'BCL2 apoptosis regulator', 'mesh_heading': 'Carcinoma, Non... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1898 | Q6 | What genes does Ixabepilone target when it's used to treat neoplasm? | When used to treat neoplasm, the drug Ixabepilone targets the genes TUBB4B, TUBB1, TUBA3C, TUBA4A, TUBB3, TUBA1A, TUBB4A, TUBB8, TUBB, TUBA1B, TUBA1C, TUBA3E, TUBB2A, TUBB2B, and TUBB6. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ixabepilone%" OR LOWER(tradeNames_list) LIKE "%ix... | [{'UUID': 'DrugTargetsIndication121923_text_85346', 'drugName': 'Ixabepilone', 'tradeNames_list': "['Ixempra', 'Ixempra kit']", 'syns_list': "['Azaepothilone b', 'BMS 247550-01', 'BMS-247550', 'BMS-247550-01Ixabepilone', 'Ixempra', 'NSC-747973']", 'target': 'ENSG00000188229', 'approvedSymbol': 'TUBB4B', 'approvedName':... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.918 | Q6 | What genes does Hydrocortisone target when it's used to treat ulcerative colitis? | When used to treat ulcerative colitis, the drug Hydrocortisone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%hydrocortisone%" OR LOWER(tradeNames_list) LIKE "... | [{'UUID': 'DrugTargetsIndication121923_text_218675', 'drugName': 'Prednisone', 'tradeNames_list': "['Cortan', 'Cortancyl', 'Decortisyl', 'Delta-dome', 'Deltasone', 'FernisoneLiquid pred', 'Lodotra', 'Meticorten', 'Orasone', 'Paracort', 'Prednicen-mPrednisone', 'Prednisone intensol', 'Rayos', 'Servisone', 'Sterapred']",... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1930 | Q6 | What genes does Levomilnacipran Hydrochloride target when it's used to treat major depressive disorder? | When used to treat major depressive disorder, the drug Levomilnacipran Hydrochloride targets the genes SLC6A4 and SLC6A2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%levomilnacipran hydrochloride%" OR LOWER(tradeNam... | [{'UUID': 'DrugTargetsIndication121923_text_206894', 'drugName': 'Levomilnacipran Hydrochloride', 'tradeNames_list': "['Fetzima']", 'syns_list': "['(1s,2r)-milnacipran hydrochloride', 'F 2695 HYDROCHLORIDEF-2695 HYDROCHLORIDE', 'F2695', 'F2695 HYDROCHLORIDELevomilnacipran hydrochloride']", 'target': 'ENSG00000108576', ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1126 | Q6 | What genes does Lorazepam target when it's used to treat reflex epilepsy? | Lorazepam has not been approved by the FDA as a treatment for reflex epilepsy, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are GABRA1, GABRB2, GABRG2, GABRB3, GABRA4, GABRG3, GABRQ, GABRA3, GABRP, GABRD, GABRG1, GABRB1, GABRE, GABRA2, GABRA5, and GABRA6. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lorazepam%" OR LOWER(tradeNames_list) LIKE "%lora... | [{'UUID': 'DrugTargetsIndication121923_text_958593', 'drugName': 'Lorazepam', 'tradeNames_list': "['Abbloraz', 'Ativan', 'Loraz', 'Lorazepam', 'Lorazepam intensolLorazepam preservative free', 'Loreev xr', 'Temesta']", 'syns_list': "['Lorazepam', 'Lorazepam civ', 'NSC-289758', 'WY-4036']", 'target': 'ENSG00000145864', '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.332 | Q6 | What genes does Trametinib Dimethyl Sulfoxide target when it's used to treat cutaneous melanoma? | When used to treat cutaneous melanoma, the drug Trametinib Dimethyl Sulfoxide targets the genes MAP2K2 and MAP2K1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%trametinib dimethyl sulfoxide%" OR LOWER(tradeNam... | [{'UUID': 'DrugTargetsIndication121923_text_927764', 'drugName': 'Trametinib Dimethyl Sulfoxide', 'tradeNames_list': "['Mekinist']", 'syns_list': "['GSK-1120212B', 'GSK1120212B', 'Trametinib dimethyl sulfoxide']", 'target': 'ENSG00000126934', 'approvedSymbol': 'MAP2K2', 'approvedName': 'mitogen-activated protein kinase... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1036 | Q6 | What genes does Dronabinol target when it's used to treat essential tremor? | Dronabinol has not been approved by the FDA as a treatment for essential tremor, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is CNR1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dronabinol%" OR LOWER(tradeNames_list) LIKE "%dro... | [{'UUID': 'DrugTargetsIndication121923_text_1073224', 'drugName': 'Dronabinol', 'tradeNames_list': "['Dronabinol', 'Marinol', 'Syndros']", 'syns_list': "['.delta.-9-tetrahydrocannabinol', '.delta.1-thc.delta.9-tetrahydrocannabinol', '.delta.9-thc', 'ABBOTT 40566ABBOTT-40566', 'Delta-9-tetrahydrocannabinol', 'Delta-9-th... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.322 | Q6 | What genes does Enzalutamide target when it's used to treat Mantle cell lymphoma? | Enzalutamide has not been approved by the FDA as a treatment for Mantle cell lymphoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is AR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%enzalutamide%" OR LOWER(tradeNames_list) LIKE "%e... | [{'UUID': 'DrugTargetsIndication121923_text_921117', 'drugName': 'Enzalutamide', 'tradeNames_list': "['Xtandi']", 'syns_list': "['Enzalutamide', 'MDV-3100', 'MDV3100', 'Mdv 3100']", 'target': 'ENSG00000169083', 'approvedSymbol': 'AR', 'approvedName': 'androgen receptor', 'mesh_heading': 'Lymphoma, Mantle-Cell', 'efo_te... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1531 | Q6 | What genes does Apremilast target when it's used to treat Oral ulcer? | When used to treat Oral ulcer, the drug Apremilast targets the genes PDE4A, PDE4D, PDE4B, and PDE4C. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%apremilast%" OR LOWER(tradeNames_list) LIKE "%apr... | [{'UUID': 'DrugTargetsIndication121923_text_696931', 'drugName': 'Apremilast', 'tradeNames_list': "['Otezla']", 'syns_list': "['Apremilast', 'CC-10004', 'CC10004']", 'target': 'ENSG00000065989', 'approvedSymbol': 'PDE4A', 'approvedName': 'phosphodiesterase 4A', 'mesh_heading': 'Oral Ulcer', 'efo_term': 'Oral ulcer', 'y... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1360 | Q6 | What genes does Valbenazine Tosylate target when it's used to treat movement disorder? | When used to treat movement disorder, the drug Valbenazine Tosylate targets the gene SLC18A2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%valbenazine tosylate%" OR LOWER(tradeNames_list) ... | [{'UUID': 'DrugTargetsIndication121923_text_938929', 'drugName': 'Valbenazine Tosylate', 'tradeNames_list': "['Ingrezza']", 'syns_list': "['NBI-98854', 'Valbenazine ditosylate', 'Valbenazine tosilateValbenazine tosylate']", 'target': 'ENSG00000165646', 'approvedSymbol': 'SLC18A2', 'approvedName': 'solute carrier family... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1734 | Q6 | What genes does Exenatide target when it's used to treat diabetes mellitus? | When used to treat diabetes mellitus, the drug Exenatide targets the gene GLP1R. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%exenatide%" OR LOWER(tradeNames_list) LIKE "%exen... | [{'UUID': 'DrugTargetsIndication121923_text_1046868', 'drugName': 'Exenatide', 'tradeNames_list': "['Bydureon', 'Bydureon bcise', 'Bydureon pen', 'Byetta']", 'syns_list': "['AC 2993', 'AC-002993', 'AC-2993', 'AC-2993A', 'AC-2993LAR', 'AC002993AC2993', 'AC2993A', 'DA-3091', 'EXENDIN-4', 'ExenatideExenatide Synthetic', '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.170 | Q6 | What genes does Paclitaxel target when it's used to treat thyroid carcinoma? | Paclitaxel has not been approved by the FDA as a treatment for thyroid carcinoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are TUBB4B, TUBB1, TUBA3C, TUBA4A, TUBB3, TUBA1A, TUBB4A, TUBB8, TUBB, TUBA1B, TUBA1C, TUBA3E, TUBB2A, TUBB2B, and TUBB6. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%paclitaxel%" OR LOWER(tradeNames_list) LIKE "%pac... | [{'UUID': 'DrugTargetsIndication121923_text_875', 'drugName': 'Paclitaxel', 'tradeNames_list': "['Abraxane', 'Pacitaxel', 'Paclitaxel', 'Paxene', 'Taxol', 'Taxol 100']", 'syns_list': "['(-)-paclitaxel', 'ABI-007', 'ABI-007 COMPONENT PACLITAXEL', 'BMS 181339-01BMS-181339-01', 'Capxol', 'Cyclopax', 'DHP 107', 'DHP-107', ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.13 | Q6 | What genes does Eteplirsen target when it's used to treat muscular dystrophy? | When used to treat muscular dystrophy, the drug Eteplirsen targets the gene DMD. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%eteplirsen%" OR LOWER(tradeNames_list) LIKE "%ete... | [{'UUID': 'DrugTargetsIndication121923_text_1100453', 'drugName': 'Eteplirsen', 'tradeNames_list': "['Exondys 51']", 'syns_list': "['AVI-4658', 'Eteplirsen']", 'target': 'ENSG00000198947', 'approvedSymbol': 'DMD', 'approvedName': 'dystrophin', 'mesh_heading': 'Muscular Dystrophies', 'efo_term': 'muscular dystrophy', 'y... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1927 | Q6 | What genes does Cobicistat target when it's used to treat HIV-1 infection? | When used to treat HIV-1 infection, the drug Cobicistat targets the genes CYP3A4, CYP3A5, CYP3A43, and CYP3A7. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%cobicistat%" OR LOWER(tradeNames_list) LIKE "%cob... | [{'UUID': 'DrugTargetsIndication121923_text_1148831', 'drugName': 'Cobicistat', 'tradeNames_list': "['Tybost']", 'syns_list': "['Cobicistat', 'Cobicistat on silicon dioxide', 'Cobicistat, (r,r,s)-GS-9350']", 'target': 'ENSG00000106258', 'approvedSymbol': 'CYP3A5', 'approvedName': 'cytochrome P450 family 3 subfamily A m... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.174 | Q6 | What genes does Midazolam target when it's used to treat relapsing-remitting multiple sclerosis? | Midazolam has not been approved by the FDA as a treatment for relapsing-remitting multiple sclerosis, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are GABRA1, GABRB2, GABRG2, GABRB3, GABRA4, GABRG3, GABRQ, GABRA3, GABRP, GABRD, GABRG1, GABRB1, GABRE, GABRA2, G... | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%midazolam%" OR LOWER(tradeNames_list) LIKE "%mida... | [{'UUID': 'DrugTargetsIndication121923_text_949043', 'drugName': 'Midazolam', 'tradeNames_list': "['Midazolam in 0.8% sodium chloride', 'Midazolam in 0.9% sodium chlorideNayzilam']", 'syns_list': "['Midazolam', 'Midazolam civ', 'USL-261', 'USL261']", 'target': 'ENSG00000022355', 'approvedSymbol': 'GABRA1', 'approvedNam... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.656 | Q6 | What genes does Selpercatinib target when it's used to treat non-small cell lung carcinoma? | When used to treat non-small cell lung carcinoma, the drug Selpercatinib targets the genes RET, CCDC6, and KIF5B. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%selpercatinib%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_944410', 'drugName': 'Selpercatinib', 'tradeNames_list': "['Retevmo']", 'syns_list': "['LOXO-292', 'LY-3527723', 'LY3527723', 'Loxo-292', 'Ret inhibitor loxo-292Selpercatinib']", 'target': 'ENSG00000165731', 'approvedSymbol': 'RET', 'approvedName': 'ret proto-oncogene', 'mesh... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1062 | Q6 | What genes does Octreotide Acetate target when it's used to treat familial hyperinsulinism? | Octreotide Acetate has not been approved by the FDA as a treatment for familial hyperinsulinism, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are SSTR5, SSTR2, SSTR3, SSTR1, and SSTR4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%octreotide acetate%" OR LOWER(tradeNames_list) LI... | [{'UUID': 'DrugTargetsIndication121923_text_1042114', 'drugName': 'Octreotide Acetate', 'tradeNames_list': "['Bynfezia pen', 'Mycapssa', 'Octreotide acetateOctreotide acetate (preservative free)Octreotide acetate preservative free', 'Sandostatin', 'Sandostatin lar']", 'syns_list': "['Octreolin', 'Octreotide (as acetate... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.263 | Q6 | What genes does Triamcinolone Acetonide target when it's used to treat pulmonary tuberculosis? | When used to treat pulmonary tuberculosis, the drug Triamcinolone Acetonide targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%triamcinolone acetonide%" OR LOWER(tradeNames_lis... | [{'UUID': 'DrugTargetsIndication121923_text_222205', 'drugName': 'Triamcinolone Acetonide', 'tradeNames_list': "['Adcortyl', 'Adcortyl in orabase', 'Allernaze', 'Aristocort', 'Aristocort aAristogel', 'Audicort', 'Aureocort', 'Azmacort', 'Flutex', 'Gppe ear dps capGppe ear oint', 'Kenacort', 'Kenalog', 'Kenalog in oraba... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1427 | Q6 | What genes does Temsirolimus target when it's used to treat cancer? | When used to treat cancer, the drug Temsirolimus targets the gene FKBP1A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%temsirolimus%" OR LOWER(tradeNames_list) LIKE "%t... | [{'UUID': 'DrugTargetsIndication121923_text_1091012', 'drugName': 'Temsirolimus', 'tradeNames_list': "['Torisel']", 'syns_list': "['CCI-779', 'Temsirolimus']", 'target': 'ENSG00000088832', 'approvedSymbol': 'FKBP1A', 'approvedName': 'FKBP prolyl isomerase 1A', 'mesh_heading': 'Neoplasms', 'efo_term': 'cancer', 'yearOfF... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1582 | Q6 | What genes does Thalidomide target when it's used to treat Central Nervous System Neoplasm? | Thalidomide has not been approved by the FDA as a treatment for Central Nervous System Neoplasm, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are CRBN, DDB1, CUL4A, and RBX1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%thalidomide%" OR LOWER(tradeNames_list) LIKE "%th... | [{'UUID': 'DrugTargetsIndication121923_text_1105082', 'drugName': 'Thalidomide', 'tradeNames_list': "['Talidex', 'Thalomid']", 'syns_list': "['.alpha.-phthalimidoglutarimide', 'Celgene', 'Contergan', 'Distaval', 'K-17Myrin', 'N-phthalylglutamic acid imide', 'NSC-527179', 'NSC-66847Neurosedyn', 'Pantosediv', 'Pharmion',... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.909 | Q6 | What genes does Omeprazole target when it's used to treat peptic ulcer disease? | When used to treat peptic ulcer disease, the drug Omeprazole targets the genes ATP4A and ATP4B. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%omeprazole%" OR LOWER(tradeNames_list) LIKE "%ome... | [{'UUID': 'DrugTargetsIndication121923_text_1098040', 'drugName': 'Omeprazole', 'tradeNames_list': "['Antra', 'Losec', 'Losec mups', 'Mezzopram', 'Mopral', 'Omeprazole', 'OmeranPrilosec', 'Zanprol']", 'syns_list': "['H 168/68', 'H-168/68', 'NSC-751450', 'NSC-759192', 'Omeprazole']", 'target': 'ENSG00000105675', 'approv... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.679 | Q6 | What genes does Levothyroxine Sodium target when it's used to treat congenital hypothyroidism? | When used to treat congenital hypothyroidism, the drug Levothyroxine Sodium targets the genes THRA and THRB. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%levothyroxine sodium%" OR LOWER(tradeNames_list) ... | [{'UUID': 'DrugTargetsIndication121923_text_924837', 'drugName': 'Levothyroxine Sodium', 'tradeNames_list': "['Eltroxin', 'Ermeza', 'Euthyrox', 'Evotrox', 'L-thyroxine henning', 'Levo-tLevolet', 'Levothroid', 'Levothyroid', 'Levothyroxine sodium', 'LevoxineLevoxyl', 'Novothyrox', 'Soloxine', 'Synthroid', 'Thyquidity', ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.261 | Q6 | What genes does Lidocaine target when it's used to treat neuralgia? | When used to treat neuralgia, the drug Lidocaine targets the genes SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lidocaine%" OR LOWER(tradeNames_list) LIKE "%lido... | [{'UUID': 'DrugTargetsIndication121923_text_638823', 'drugName': 'Lidocaine', 'tradeNames_list': "['Alphacaine', 'Anestacon', 'Dentipatch', 'Lidocaine', 'LidodermLignocaine Hcl', 'Lignostab', 'Lmx 4', 'Oraqix', 'Vagisil', 'XylocaineXylodase', 'Xylotox', 'Ztlido']", 'syns_list': "['ALGRX 3268', 'ALGRX-3268', 'Anestacon'... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.851 | Q6 | What genes does Budesonide target when it's used to treat chronic obstructive pulmonary disease? | When used to treat chronic obstructive pulmonary disease, the drug Budesonide targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%budesonide%" OR LOWER(tradeNames_list) LIKE "%bud... | [{'UUID': 'DrugTargetsIndication121923_text_222611', 'drugName': 'Budesonide', 'tradeNames_list': "['Aircort', 'Budeflam aquanase', 'Budelin novolizer', 'BudenofalkBudesonide', 'Cortiment', 'Duoresp spiromax', 'Entocort', 'Entocort crEntocort ec', 'Ortikos', 'Preferid', 'Pulmaxan', 'PulmicortPulmicort flexhaler', 'Pulm... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.874 | Q6 | What genes does Metoprolol Succinate target when it's used to treat congestive heart failure? | When used to treat congestive heart failure, the drug Metoprolol Succinate targets the gene ADRB1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%metoprolol succinate%" OR LOWER(tradeNames_list) ... | [{'UUID': 'DrugTargetsIndication121923_text_937655', 'drugName': 'Metoprolol Succinate', 'tradeNames_list': "['Kapspargo sprinkle', 'Metoprolol succinate', 'Toprol', 'Toprol XlToprol-xl']", 'syns_list': "['H 93/26 SUCCINATE', 'Metoprolol hemisuccinate', 'Metoprolol succinateSeloken-zok', 'Selozok']", 'target': 'ENSG000... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1564 | Q6 | What genes does Dexamethasone target when it's used to treat Henoch-Schoenlein purpura? | Dexamethasone has not been approved by the FDA as a treatment for Henoch-Schoenlein purpura, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dexamethasone%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_227594', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.141 | Q6 | What genes does Zoledronic Acid target when it's used to treat metastatic prostate cancer? | When used to treat metastatic prostate cancer, the drug Zoledronic Acid targets the gene FDPS. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%zoledronic acid%" OR LOWER(tradeNames_list) LIKE ... | [{'UUID': 'DrugTargetsIndication121923_text_1099873', 'drugName': 'Zoledronic Acid', 'tradeNames_list': "['Aclasta', 'Reclast', 'Zerlinda', 'Zoledronic acid', 'Zometa']", 'syns_list': "['AK-156', 'Anhydrous zoledronic acid', 'CGP 42446', 'CGP-42446', 'CGP-42446ANSC-721517', 'Zoladrona acid mylan', 'Zoledronate', 'Zoled... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.900 | Q6 | What genes does Triptorelin Pamoate target when it's used to treat Central precocious puberty? | When used to treat Central precocious puberty, the drug Triptorelin Pamoate targets the gene GNRHR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%triptorelin pamoate%" OR LOWER(tradeNames_list) L... | [{'UUID': 'DrugTargetsIndication121923_text_1097287', 'drugName': 'Triptorelin Pamoate', 'tradeNames_list': "['Trelstar', 'Triptodur kit']", 'syns_list': "['Salvacyl', 'Triptorelin (as embonate)', 'Triptorelin embonateTriptorelin pamoate']", 'target': 'ENSG00000109163', 'approvedSymbol': 'GNRHR', 'approvedName': 'gonad... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1839 | Q6 | What genes does Lenvatinib target when it's used to treat cervical cancer? | Lenvatinib has not been approved by the FDA as a treatment for cervical cancer, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are KDR, FLT1, and FLT4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lenvatinib%" OR LOWER(tradeNames_list) LIKE "%len... | [{'UUID': 'DrugTargetsIndication121923_text_690796', 'drugName': 'Lenvatinib', 'tradeNames_list': "['Kisplyx', 'Lenvima']", 'syns_list': "['E-7080', 'ER-203492-00', 'Lenvatinib']", 'target': 'ENSG00000128052', 'approvedSymbol': 'KDR', 'approvedName': 'kinase insert domain receptor', 'mesh_heading': 'Uterine Cervical Ne... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.555 | Q6 | What genes does Amantadine Hydrochloride target when it's used to treat Parkinsonism? | When used to treat Parkinsonism, the drug Amantadine Hydrochloride targets the genes GRIN1, GRIN2A, GRIN2B, GRIN2D, GRIN3B, GRIN2C, and GRIN3A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%amantadine hydrochloride%" OR LOWER(tradeNames_li... | [{'UUID': 'DrugTargetsIndication121923_text_441088', 'drugName': 'Amantadine Hydrochloride', 'tradeNames_list': "['Amantadine hydrochloride', 'Gocovri', 'Lysovir', 'Mantadine', 'Osmolex erSymadine', 'Symmetrel']", 'syns_list': "['Adamantanamine hydrochloride', 'Amantadine hclAmantadine hydrochloride', 'EXP-105-1', 'Man... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.323 | Q6 | What genes does Palbociclib target when it's used to treat breast neoplasm? | When used to treat breast neoplasm, the drug Palbociclib targets the genes CDK4, CDK6, and CCND1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%palbociclib%" OR LOWER(tradeNames_list) LIKE "%pa... | [{'UUID': 'DrugTargetsIndication121923_text_851403', 'drugName': 'Palbociclib', 'tradeNames_list': "['Ibrance']", 'syns_list': "['PD-0332991', 'Palbociclib']", 'target': 'ENSG00000135446', 'approvedSymbol': 'CDK4', 'approvedName': 'cyclin dependent kinase 4', 'mesh_heading': 'Breast Neoplasms', 'efo_term': 'breast canc... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1854 | Q6 | What genes does Sirolimus target when it's used to treat Abnormality of the cardiovascular system? | Sirolimus has not been approved by the FDA as a treatment for Abnormality of the cardiovascular system, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is FKBP1A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%sirolimus%" OR LOWER(tradeNames_list) LIKE "%siro... | [{'UUID': 'DrugTargetsIndication121923_text_1084541', 'drugName': 'Sirolimus', 'tradeNames_list': "['Fyarro', 'Hyftor', 'Rapamune', 'Sirolimus']", 'syns_list': "['AY-22989', 'Fyarro', 'Hyftor', 'L04AA10', 'NSC-226080', 'Npc-12g', 'RapalimusRapamycin', 'SM-88 COMPONENT SIROLIMUS', 'Sirolimus', 'WY-090217']", 'target': '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1235 | Q6 | What genes does Eslicarbazepine Acetate target when it's used to treat epilepsy? | When used to treat epilepsy, the drug Eslicarbazepine Acetate targets the genes SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%eslicarbazepine acetate%" OR LOWER(tradeNames_lis... | [{'UUID': 'DrugTargetsIndication121923_text_657471', 'drugName': 'Eslicarbazepine Acetate', 'tradeNames_list': "['Aptiom', 'Erelib', 'Pazzul', 'Stedesa', 'Zebinix']", 'syns_list': "['BIA 2-093', 'BIA-2-093', 'BIA-2093', 'Eslicarbazepine acetateSEP - 0002093', 'SEP-0002093']", 'target': 'ENSG00000183873', 'approvedSymbo... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1726 | Q6 | What genes does Dexamethasone target when it's used to treat rheumatic disease? | Dexamethasone has not been approved by the FDA as a treatment for rheumatic disease, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dexamethasone%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_227537', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.564 | Q6 | What genes does Abiraterone Acetate target when it's used to treat cancer? | When used to treat cancer, the drug Abiraterone Acetate targets the gene CYP17A1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%abiraterone acetate%" OR LOWER(tradeNames_list) L... | [{'UUID': 'DrugTargetsIndication121923_text_1094284', 'drugName': 'Abiraterone Acetate', 'tradeNames_list': "['Yonsa', 'Zytiga']", 'syns_list': "['Abiraterone acetate', 'CB-7630', 'CB7630', 'NSC-748121', 'NSC-749227']", 'target': 'ENSG00000148795', 'approvedSymbol': 'CYP17A1', 'approvedName': 'cytochrome P450 family 17... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.142 | Q6 | What genes does Escitalopram Oxalate target when it's used to treat unipolar depression? | When used to treat unipolar depression, the drug Escitalopram Oxalate targets the gene SLC6A4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%escitalopram oxalate%" OR LOWER(tradeNames_list) ... | [{'UUID': 'DrugTargetsIndication121923_text_206519', 'drugName': 'Escitalopram Oxalate', 'tradeNames_list': "['Escitalopram oxalate', 'Lexapro']", 'syns_list': "['Citalopram oxalate, (s)-', 'Escitalopram (as oxalate)Escitalopram oxalate', 'LU 26-054-0', 'LU-26-054-0', 'LU-26-054-ONSC-758934']", 'target': 'ENSG000001085... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1736 | Q6 | What genes does Afatinib Dimaleate target when it's used to treat non-small cell lung carcinoma? | When used to treat non-small cell lung carcinoma, the drug Afatinib Dimaleate targets the genes EGFR, ERBB2, and ERBB4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%afatinib dimaleate%" OR LOWER(tradeNames_list) LI... | [{'UUID': 'DrugTargetsIndication121923_text_207186', 'drugName': 'Afatinib Dimaleate', 'tradeNames_list': "['Gilotrif']", 'syns_list': "['Afatinib dimaleate', 'Afatinib maleate', 'BIBW-2992 MA2', 'BIBW-2992-MA2BIBW-2992MA2', 'BIBW2992 MA2', 'BIBW2992-MA2']", 'target': 'ENSG00000146648', 'approvedSymbol': 'EGFR', 'appro... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.537 | Q6 | What genes does Mifepristone target when it's used to treat peritoneum cancer? | Mifepristone has not been approved by the FDA as a treatment for peritoneum cancer, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are NR3C1 and PGR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%mifepristone%" OR LOWER(tradeNames_list) LIKE "%m... | [{'UUID': 'DrugTargetsIndication121923_text_242458', 'drugName': 'Mifepristone', 'tradeNames_list': "['Korlym', 'Mifegyne', 'Mifeprex']", 'syns_list': "['Mifepristone', 'NSC-759862', 'RU 38486', 'RU 486', 'RU-38486', 'RU-486RU486']", 'target': 'ENSG00000113580', 'approvedSymbol': 'NR3C1', 'approvedName': 'nuclear recep... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.227 | Q6 | What genes does Revefenacin target when it's used to treat chronic obstructive pulmonary disease? | When used to treat chronic obstructive pulmonary disease, the drug Revefenacin targets the gene CHRM3. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%revefenacin%" OR LOWER(tradeNames_list) LIKE "%re... | [{'UUID': 'DrugTargetsIndication121923_text_857811', 'drugName': 'Revefenacin', 'tradeNames_list': "['Yupelri']", 'syns_list': "['GSK-1160724', 'GSK1160724', 'Revefenacin', 'TD-4208']", 'target': 'ENSG00000133019', 'approvedSymbol': 'CHRM3', 'approvedName': 'cholinergic receptor muscarinic 3', 'mesh_heading': 'Pulmonar... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.730 | Q6 | What genes does Dexamethasone target when it's used to treat eye disease? | When used to treat eye disease, the drug Dexamethasone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dexamethasone%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_226915', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.793 | Q6 | What genes does Pregabalin target when it's used to treat Seizure? | When used to treat Seizure, the drug Pregabalin targets the genes CACNA1B, CACNA1C, CACNA1S, CACNA1D, CACNA1F, CACNA2D2, CACNA2D1, CACNA1H, CACNA1G, CACNA1I, CACNA1A, CACNA2D3, CACNA2D4, CACNA1E, CACNB4, CACNB2, CACNB1, CACNB3, CACNG7, CACNG5, CACNG2, CACNG4, CACNG8, CACNG3, CACNG6, and CACNG1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%pregabalin%" OR LOWER(tradeNames_list) LIKE "%pre... | [{'UUID': 'DrugTargetsIndication121923_text_861560', 'drugName': 'Pregabalin', 'tradeNames_list': "['Alzain', 'Axalid', 'Lecaent', 'Lyrica', 'Lyrica cr', 'Pregabalin', 'Rewisca']", 'syns_list': "['CI-1008', 'NSC-759256', 'PD-144723', 'Pregabalin', 'Pregabalin mylanPregabalin sandoz', 'Pregabalin sandoz gmbh', 'Pregabal... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1718 | Q6 | What genes does Aripiprazole Lauroxil target when it's used to treat major depressive disorder? | When used to treat major depressive disorder, the drug Aripiprazole Lauroxil targets the genes DRD2, HTR2A, and HTR1A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%aripiprazole lauroxil%" OR LOWER(tradeNames_list)... | [{'UUID': 'DrugTargetsIndication121923_text_158030', 'drugName': 'Aripiprazole Lauroxil', 'tradeNames_list': "['Aristada', 'Aristada initio kit']", 'syns_list': "['ALKS 9072', 'ALKS-9070', 'ALKS-9072', 'Aripiprazole lauroxilAristada initio', 'RDC-3317', 'RDC3317']", 'target': 'ENSG00000149295', 'approvedSymbol': 'DRD2'... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.994 | Q6 | What genes does Progesterone target when it's used to treat amenorrhea? | When used to treat amenorrhea, the drug Progesterone targets the gene PGR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%progesterone%" OR LOWER(tradeNames_list) LIKE "%p... | [{'UUID': 'DrugTargetsIndication121923_text_940055', 'drugName': 'Progesterone', 'tradeNames_list': "['Crinone', 'Cyclogest', 'Endometrin', 'Gesterol', 'Lutigest', 'MilprosaProchieve', 'Progesta-care', 'Progestasert', 'Progesterone', 'ProgestinPrometrium', 'Regumate', 'Serenity for women', 'Syngestrone', 'Utrogestan']"... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.415 | Q6 | What genes does Alendronate Sodium target when it's used to treat osteoporosis? | When used to treat osteoporosis, the drug Alendronate Sodium targets the gene FDPS. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%alendronate sodium%" OR LOWER(tradeNames_list) LI... | [{'UUID': 'DrugTargetsIndication121923_text_1099505', 'drugName': 'Alendronate Sodium', 'tradeNames_list': "['Alendronate sodium', 'Binosto', 'Fosamax']", 'syns_list': "['Adrovance', 'Alendronate (as sodium)', 'Alendronate sodiumAlendronate sodium hydrate', 'Alendronate sodium trihydrateAlendronic acid monosodium salt ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.329 | Q6 | What genes does Topotecan target when it's used to treat malignant epithelial tumor of ovary? | Topotecan has not been approved by the FDA as a treatment for malignant epithelial tumor of ovary, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is TOP1MT. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%topotecan%" OR LOWER(tradeNames_list) LIKE "%topo... | [{'UUID': 'DrugTargetsIndication121923_text_1193579', 'drugName': 'Topotecan Hydrochloride', 'tradeNames_list': "['Hycamptin', 'Hycamtin', 'Topotecan', 'Topotecan hydrochloride']", 'syns_list': "['Evotopin', 'NSC-759263', 'Nogitecan hydrochloride', 'SK&F S-104864-ASK&F-S-104864A', 'SK-S-104864-A', 'Topotecan (as hydroc... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1098 | Q6 | What genes does Osilodrostat Phosphate target when it's used to treat pituitary-dependent Cushing's disease? | When used to treat pituitary-dependent Cushing's disease, the drug Osilodrostat Phosphate targets the gene CYP11B1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%osilodrostat phosphate%" OR LOWER(tradeNames_list... | [{'UUID': 'DrugTargetsIndication121923_text_1100346', 'drugName': 'Osilodrostat Phosphate', 'tradeNames_list': "['Isturisa']", 'syns_list': "['LCI699-AZA', 'Osilodrostat phosphate']", 'target': 'ENSG00000160882', 'approvedSymbol': 'CYP11B1', 'approvedName': 'cytochrome P450 family 11 subfamily B member 1', 'mesh_headin... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.303 | Q6 | What genes does Carfilzomib target when it's used to treat unspecified peripheral T-cell lymphoma? | Carfilzomib has not been approved by the FDA as a treatment for unspecified peripheral T-cell lymphoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are PSMD1, PSMB2, PSMB1, PSMB5, PSMB8, PSMB9, PSMB6, PSMD14, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMA7, P... | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%carfilzomib%" OR LOWER(tradeNames_list) LIKE "%ca... | [{'UUID': 'DrugTargetsIndication121923_text_268014', 'drugName': 'Carfilzomib', 'tradeNames_list': "['Kyprolis']", 'syns_list': "['Carfilzomib', 'NSC-758252', 'PR-171']", 'target': 'ENSG00000173692', 'approvedSymbol': 'PSMD1', 'approvedName': 'proteasome 26S subunit, non-ATPase 1', 'mesh_heading': 'Lymphoma, T-Cell, Pe... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1259 | Q6 | What genes does Prednisone target when it's used to treat subacute thyroiditis? | When used to treat subacute thyroiditis, the drug Prednisone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%prednisone%" OR LOWER(tradeNames_list) LIKE "%pre... | [{'UUID': 'DrugTargetsIndication121923_text_218712', 'drugName': 'Prednisone', 'tradeNames_list': "['Cortan', 'Cortancyl', 'Decortisyl', 'Delta-dome', 'Deltasone', 'FernisoneLiquid pred', 'Lodotra', 'Meticorten', 'Orasone', 'Paracort', 'Prednicen-mPrednisone', 'Prednisone intensol', 'Rayos', 'Servisone', 'Sterapred']",... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1996 | Q6 | What genes does Metoclopramide Hydrochloride target when it's used to treat Nausea and vomiting? | When used to treat Nausea and vomiting, the drug Metoclopramide Hydrochloride targets the genes DRD2, HTR3A, and HTR4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%metoclopramide hydrochloride%" OR LOWER(tradeName... | [{'UUID': 'DrugTargetsIndication121923_text_199679', 'drugName': 'Metoclopramide Hydrochloride', 'tradeNames_list': '[\'"clopra-""yellow"""\', \'Clopra\', \'Clopra-"Yellow"\', \'Gastrese l.a.Gastrobid continus\', \'Gastroflux\', \'Gastromax\', \'Gimoti\', \'MaxolonMaxolon sr\', \'Metoclomex\', \'Metoclopramide hydrochl... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.26 | Q6 | What genes does Metoprolol Succinate target when it's used to treat heart failure? | When used to treat heart failure, the drug Metoprolol Succinate targets the gene ADRB1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%metoprolol succinate%" OR LOWER(tradeNames_list) ... | [{'UUID': 'DrugTargetsIndication121923_text_937624', 'drugName': 'Metoprolol Succinate', 'tradeNames_list': "['Kapspargo sprinkle', 'Metoprolol succinate', 'Toprol', 'Toprol XlToprol-xl']", 'syns_list': "['H 93/26 SUCCINATE', 'Metoprolol hemisuccinate', 'Metoprolol succinateSeloken-zok', 'Selozok']", 'target': 'ENSG000... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1860 | Q6 | What genes does Pregabalin target when it's used to treat epilepsy? | When used to treat epilepsy, the drug Pregabalin targets the genes CACNA1B, CACNA1C, CACNA1S, CACNA1D, CACNA1F, CACNA2D2, CACNA2D1, CACNA1H, CACNA1G, CACNA1I, CACNA1A, CACNA2D3, CACNA2D4, CACNA1E, CACNB4, CACNB2, CACNB1, CACNB3, CACNG7, CACNG5, CACNG2, CACNG4, CACNG8, CACNG3, CACNG6, and CACNG1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%pregabalin%" OR LOWER(tradeNames_list) LIKE "%pre... | [{'UUID': 'DrugTargetsIndication121923_text_863018', 'drugName': 'Pregabalin', 'tradeNames_list': "['Alzain', 'Axalid', 'Lecaent', 'Lyrica', 'Lyrica cr', 'Pregabalin', 'Rewisca']", 'syns_list': "['CI-1008', 'NSC-759256', 'PD-144723', 'Pregabalin', 'Pregabalin mylanPregabalin sandoz', 'Pregabalin sandoz gmbh', 'Pregabal... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.721 | Q6 | What genes does Carbamazepine target when it's used to treat partial epilepsy? | When used to treat partial epilepsy, the drug Carbamazepine targets the genes SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%carbamazepine%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_651945', 'drugName': 'Carbamazepine', 'tradeNames_list': "['Arbil mr', 'Carbagen sr', 'Carbamazepine', 'Carbatrol', 'Carnexiv', 'EpimazEpimaz ret', 'Epitol', 'Equetro', 'Sirtal ret', 'Tegretol', 'Tegretol XrTegretol chewtab', 'Tegretol prolonged release', 'Tegretol-xr', 'Teri... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.996 | Q6 | What genes does Berotralstat Hydrochloride target when it's used to treat hereditary angioedema? | When used to treat hereditary angioedema, the drug Berotralstat Hydrochloride targets the gene KLKB1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%berotralstat hydrochloride%" OR LOWER(tradeNames_... | [{'UUID': 'DrugTargetsIndication121923_text_1095501', 'drugName': 'Berotralstat Hydrochloride', 'tradeNames_list': "['Orladeyo']", 'syns_list': "['BCX7353.2HCl', 'Berotralstat dihydrochlorideBerotralstat hydrochloride']", 'target': 'ENSG00000164344', 'approvedSymbol': 'KLKB1', 'approvedName': 'kallikrein B1', 'mesh_hea... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.196 | Q6 | What genes does Dexamethasone target when it's used to treat allergic rhinitis? | When used to treat allergic rhinitis, the drug Dexamethasone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dexamethasone%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_226916', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.446 | Q6 | What genes does Avacopan target when it's used to treat Granulomatosis with Polyangiitis? | When used to treat Granulomatosis with Polyangiitis, the drug Avacopan targets the gene C5AR1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%avacopan%" OR LOWER(tradeNames_list) LIKE "%avaco... | [{'UUID': 'DrugTargetsIndication121923_text_1191849', 'drugName': 'Avacopan', 'tradeNames_list': "['Tavneos']", 'syns_list': "['Avacopan', 'CCX-168', 'CCX168', 'Ccx168']", 'target': 'ENSG00000197405', 'approvedSymbol': 'C5AR1', 'approvedName': 'complement C5a receptor 1', 'mesh_heading': 'Granulomatosis with Polyangiit... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.579 | Q6 | What genes does Fludarabine Phosphate target when it's used to treat psoriasis? | Fludarabine Phosphate has not been approved by the FDA as a treatment for psoriasis, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are POLA1, POLD4, POLD3, POLD1, POLD2, POLE, POLA2, PRIM1, PRIM2, POLE2, POLE3, RRM1, RRM2B, and RRM2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fludarabine phosphate%" OR LOWER(tradeNames_list)... | [{'UUID': 'DrugTargetsIndication121923_text_754553', 'drugName': 'Fludarabine Phosphate', 'tradeNames_list': "['Fludara', 'Fludarabine phosphate', 'Oforta']", 'syns_list': '[\'2-f-ara-amp\', \'2-f-araa\', \'2-fluoro ara-a\', \'2-fluorovidarabineFludarabine\', "Fludarabine 5\'-monophosphateFludarabine monophosphateFluda... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.955 | Q6 | What genes does Encorafenib target when it's used to treat pancreatic carcinoma? | Encorafenib has not been approved by the FDA as a treatment for pancreatic carcinoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is BRAF. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%encorafenib%" OR LOWER(tradeNames_list) LIKE "%en... | [{'UUID': 'DrugTargetsIndication121923_text_752298', 'drugName': 'Encorafenib', 'tradeNames_list': "['Braftovi']", 'syns_list': "['Encorafenib', 'Lgx-818', 'Lgx818', 'NVP-LGX-818-NXA', 'NVP-LGX818NVP-LGX818-NXA']", 'target': 'ENSG00000157764', 'approvedSymbol': 'BRAF', 'approvedName': 'B-Raf proto-oncogene, serine/thre... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.509 | Q6 | What genes does Docetaxel target when it's used to treat laryngeal squamous cell carcinoma? | Docetaxel has not been approved by the FDA as a treatment for laryngeal squamous cell carcinoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are TUBB4B, TUBB1, TUBA3C, TUBA4A, TUBB3, TUBA1A, TUBB4A, TUBB8, TUBB, TUBA1B, TUBA1C, TUBA3E, TUBB2A, TUBB2B, and TUB... | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%docetaxel%" OR LOWER(tradeNames_list) LIKE "%doce... | [{'UUID': 'DrugTargetsIndication121923_text_95974', 'drugName': 'Docetaxel', 'tradeNames_list': "['Docefrez', 'Docetaxel', 'Taxceus', 'Taxotere']", 'syns_list': "['Bind 014', 'CKD-810', 'Docetaxel', 'Docetaxel (as trihydrate)Docetaxel anhydrous', 'Docetaxel hydrate', 'Docetaxel trihydrateNSC-628503', 'RP 56976', 'RP-56... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.612 | Q6 | What genes does Doxepin Hydrochloride target when it's used to treat bipolar disorder? | When used to treat bipolar disorder, the drug Doxepin Hydrochloride targets the gene SLC6A2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%doxepin hydrochloride%" OR LOWER(tradeNames_list)... | [{'UUID': 'DrugTargetsIndication121923_text_440814', 'drugName': 'Doxepin Hydrochloride', 'tradeNames_list': "['Adapin', 'Doxepin hydrochloride', 'Quitaxon', 'Silenor', 'Sinequan', 'XepinZonalon']", 'syns_list': "['Doxepin hcl', 'Doxepin hydrochloride', 'NSC-108160', 'P-3693A']", 'target': 'ENSG00000103546', 'approvedS... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1864 | Q6 | What genes does Octreotide Acetate target when it's used to treat acromegaly? | When used to treat acromegaly, the drug Octreotide Acetate targets the genes SSTR5, SSTR2, SSTR3, SSTR1, and SSTR4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%octreotide acetate%" OR LOWER(tradeNames_list) LI... | [{'UUID': 'DrugTargetsIndication121923_text_1042125', 'drugName': 'Octreotide Acetate', 'tradeNames_list': "['Bynfezia pen', 'Mycapssa', 'Octreotide acetateOctreotide acetate (preservative free)Octreotide acetate preservative free', 'Sandostatin', 'Sandostatin lar']", 'syns_list': "['Octreolin', 'Octreotide (as acetate... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1725 | Q6 | What genes does Pitolisant Hydrochloride target when it's used to treat narcolepsy-cataplexy syndrome? | When used to treat narcolepsy-cataplexy syndrome, the drug Pitolisant Hydrochloride targets the gene HRH3. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%pitolisant hydrochloride%" OR LOWER(tradeNames_li... | [{'UUID': 'DrugTargetsIndication121923_text_828134', 'drugName': 'Pitolisant Hydrochloride', 'tradeNames_list': "['Wakix']", 'syns_list': "['Ciproxidine', 'Pitolisant hydrochloride']", 'target': 'ENSG00000101180', 'approvedSymbol': 'HRH3', 'approvedName': 'histamine receptor H3', 'mesh_heading': 'Narcolepsy', 'efo_term... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.