uuid stringlengths 4 8 | template_uuid stringclasses 40
values | question stringlengths 13 193 | answer stringlengths 29 2.2k | benchmark_query stringlengths 133 622 | execution_results stringlengths 2 1.14M | query_type stringclasses 2
values | sql_category stringclasses 26
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Q6.1885 | Q6 | What genes does Osimertinib target when it's used to treat neoplasm? | When used to treat neoplasm, the drug Osimertinib targets the gene EGFR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%osimertinib%" OR LOWER(tradeNames_list) LIKE "%os... | [{'UUID': 'DrugTargetsIndication121923_text_217195', 'drugName': 'Osimertinib', 'tradeNames_list': "['Tagrisso']", 'syns_list': "['AZD-9291', 'AZD-9291 FREE BASE', 'AZD9291', 'Azd-9291', 'MereletinibOsimertinib']", 'target': 'ENSG00000146648', 'approvedSymbol': 'EGFR', 'approvedName': 'epidermal growth factor receptor'... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.853 | Q6 | What genes does Asenapine target when it's used to treat bipolar I disorder? | When used to treat bipolar I disorder, the drug Asenapine targets the genes DRD2 and HTR2A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%asenapine%" OR LOWER(tradeNames_list) LIKE "%asen... | [{'UUID': 'DrugTargetsIndication121923_text_197590', 'drugName': 'Asenapine Maleate', 'tradeNames_list': "['Saphris']", 'syns_list': "['Asenapine (as maleate)', 'Asenapine maleate', 'ORG 5222', 'ORG-5222']", 'target': 'ENSG00000149295', 'approvedSymbol': 'DRD2', 'approvedName': 'dopamine receptor D2', 'mesh_heading': '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.4 | Q6 | What genes does Idelalisib target when it's used to treat neoplasm? | When used to treat neoplasm, the drug Idelalisib targets the gene PIK3CD. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%idelalisib%" OR LOWER(tradeNames_list) LIKE "%ide... | [{'UUID': 'DrugTargetsIndication121923_text_858416', 'drugName': 'Idelalisib', 'tradeNames_list': "['Zydelig']", 'syns_list': "['CAL-101', 'GS-1101', 'GS-11CAL-101', 'Idelalisib']", 'target': 'ENSG00000171608', 'approvedSymbol': 'PIK3CD', 'approvedName': 'phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1569 | Q6 | What genes does Acetaminophen target when it's used to treat migraine disorder? | When used to treat migraine disorder, the drug Acetaminophen targets the genes PTGS2, PTGS1, TRPV1, and FAAH. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%acetaminophen%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_829268', 'drugName': 'Acetaminophen', 'tradeNames_list': '[\'Abdine\', \'Acephen\', \'Acetaminophen\', \'Alvedon\', \'Angiers\', \'CalpolCalpol six plus\', \'Calpol six plus fastmelts\', \'Child lemsip\', \'CupanolDafalgan\', \'Datril\', \'Disprol\', \'Disprol infant\', \'Dis... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1461 | Q6 | What genes does Naproxen Sodium target when it's used to treat osteoarthritis? | When used to treat osteoarthritis, the drug Naproxen Sodium targets the genes PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%naproxen sodium%" OR LOWER(tradeNames_list) LIKE ... | [{'UUID': 'DrugTargetsIndication121923_text_838086', 'drugName': 'Naproxen Sodium', 'tradeNames_list': "['Aleve', 'Anaprox', 'Anaprox ds', 'Naprelan', 'Naproxen sodium', 'Synflex']", 'syns_list': "['BAY-117031', 'BAY117031', 'BAYH6689', 'Naproxen sodiumNaproxen sodium anhydrous', 'Naproxen sodium salt', 'RS-3650']", 't... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.473 | Q6 | What genes does Famotidine target when it's used to treat rheumatoid arthritis? | When used to treat rheumatoid arthritis, the drug Famotidine targets the gene HRH2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%famotidine%" OR LOWER(tradeNames_list) LIKE "%fam... | [{'UUID': 'DrugTargetsIndication121923_text_1100335', 'drugName': 'Famotidine', 'tradeNames_list': "['Famotidine', 'Famotidine preservative freeFamotidine preservative free (pharmacy bulk)', 'Fluxid', 'PepcidPepcid ac', 'Pepcid preservative free', 'Pepcid rpd']", 'syns_list': "['Amfamox', 'Fadul', 'Famodil', 'Famosan',... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.325 | Q6 | What genes does Dexamethasone target when it's used to treat Iridocyclitis? | When used to treat Iridocyclitis, the drug Dexamethasone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dexamethasone%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_227737', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.6 | Q6 | What genes does Alpelisib target when it's used to treat breast cancer? | When used to treat breast cancer, the drug Alpelisib targets the gene PIK3CA. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%alpelisib%" OR LOWER(tradeNames_list) LIKE "%alpe... | [{'UUID': 'DrugTargetsIndication121923_text_939631', 'drugName': 'Alpelisib', 'tradeNames_list': "['Piqray', 'Vijoice']", 'syns_list': "['Alpelisib', 'BYL-719', 'BYL719', 'Byl-719', 'NVP-BYL719', 'Vijoice']", 'target': 'ENSG00000121879', 'approvedSymbol': 'PIK3CA', 'approvedName': 'phosphatidylinositol-4,5-bisphosphate... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.225 | Q6 | What genes does Buprenorphine target when it's used to treat HIV infection? | Buprenorphine has not been approved by the FDA as a treatment for HIV infection, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are OPRM1 and OPRK1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%buprenorphine%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_764183', 'drugName': 'Buprenorphine', 'tradeNames_list': "['Bupeaze', 'Buplast', 'Butec', 'Butrans', 'Hapoctasin', 'Panitaz', 'PrenotrixReletrans', 'Sevodyne', 'Sublocade', 'Temgesic', 'Tephine', 'Transtec']", 'syns_list': "['ALKS-5461 COMPONENT BUPRENORPHINE', 'Brixadi', 'Bu... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1376 | Q6 | What genes does Rotigotine target when it's used to treat restless legs syndrome? | When used to treat restless legs syndrome, the drug Rotigotine targets the genes DRD2, DRD3, and DRD4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%rotigotine%" OR LOWER(tradeNames_list) LIKE "%rot... | [{'UUID': 'DrugTargetsIndication121923_text_200736', 'drugName': 'Rotigotine', 'tradeNames_list': "['Neupro']", 'syns_list': "['Leganto', 'Rotigotine', 'SPM 962', 'SPM-962']", 'target': 'ENSG00000149295', 'approvedSymbol': 'DRD2', 'approvedName': 'dopamine receptor D2', 'mesh_heading': 'Restless Legs Syndrome', 'efo_te... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.553 | Q6 | What genes does Treprostinil target when it's used to treat Recurrent thrombophlebitis? | When used to treat Recurrent thrombophlebitis, the drug Treprostinil targets the gene PTGIR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%treprostinil%" OR LOWER(tradeNames_list) LIKE "%t... | [{'UUID': 'DrugTargetsIndication121923_text_244533', 'drugName': 'Treprostinil', 'tradeNames_list': "['Remodulin', 'Tyvaso', 'Tyvaso dpi']", 'syns_list': "['15-AU-81', '15AU81', 'L-606', 'LRX -15', 'LRX-15', 'Rumodolin', 'TreprostinilTresprostinil', 'UT-15', 'Uniprost']", 'target': 'ENSG00000160013', 'approvedSymbol': ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.231 | Q6 | What genes does Simvastatin target when it's used to treat rheumatoid arthritis? | Simvastatin has not been approved by the FDA as a treatment for rheumatoid arthritis, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is HMGCR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%simvastatin%" OR LOWER(tradeNames_list) LIKE "%si... | [{'UUID': 'DrugTargetsIndication121923_text_1103810', 'drugName': 'Simvastatin', 'tradeNames_list': "['Flolipid', 'Lacersa', 'Ranzolont', 'Simvador', 'Simvastatin', 'ZocorZocor heart-pro']", 'syns_list': "['C10AA01', 'MK-0733', 'MK-733', 'NSC-758706', 'SimvastatinSimvastatin hydroxy acid', 'Synvinolin']", 'target': 'EN... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.40 | Q6 | What genes does Mometasone Furoate target when it's used to treat skin disease? | When used to treat skin disease, the drug Mometasone Furoate targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%mometasone furoate%" OR LOWER(tradeNames_list) LI... | [{'UUID': 'DrugTargetsIndication121923_text_242039', 'drugName': 'Mometasone Furoate', 'tradeNames_list': "['Asmanex', 'Asmanex hfa', 'Asmanex twisthaler', 'EloconMometasone furoate', 'Nasonex', 'Nasonex 24hr allergy', 'Sinuva']", 'syns_list': "['LAS-41002', 'LAS41002', 'LYR-210', 'LYR210', 'Lyr-210', 'MometasoneMometa... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.548 | Q6 | What genes does Gemcitabine Hydrochloride target when it's used to treat urinary bladder carcinoma? | Gemcitabine Hydrochloride has not been approved by the FDA as a treatment for urinary bladder carcinoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are POLA1, POLD4, POLD3, POLD1, POLD2, POLE, POLA2, PRIM1, PRIM2, POLE2, POLE3, RRM1, RRM2B, and RRM2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%gemcitabine hydrochloride%" OR LOWER(tradeNames_l... | [{'UUID': 'DrugTargetsIndication121923_text_756065', 'drugName': 'Gemcitabine Hydrochloride', 'tradeNames_list': "['Gemcitabine hydrochloride', 'Gemzar', 'Infugem']", 'syns_list': "['Gemcitabine (as hydrochloride)', 'Gemcitabine hclGemcitabine hydrochloride', 'Gemzar', 'LY-188011LY-188011 HYDROCHLORIDE', 'LY188011 HYDR... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.245 | Q6 | What genes does Oxycodone target when it's used to treat substance abuse? | When used to treat substance abuse, the drug Oxycodone targets the gene OPRM1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%oxycodone%" OR LOWER(tradeNames_list) LIKE "%oxyc... | [{'UUID': 'DrugTargetsIndication121923_text_768125', 'drugName': 'Oxycodone', 'tradeNames_list': "['Oxycontin', 'Proladone', 'Xtampza er']", 'syns_list': "['(-)-14-hydroxydihydrocodeinone', '14-hydroxydihydrocodeinone', 'DihydroneIDS-NO-002', 'N02AA05', 'NSC-19043', 'Oxicone', 'Oxycodone', 'Oxycodone ciiOxymorphone 3-m... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.905 | Q6 | What genes does Ruxolitinib Phosphate target when it's used to treat Myelofibrosis? | When used to treat Myelofibrosis, the drug Ruxolitinib Phosphate targets the genes JAK1 and JAK2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ruxolitinib phosphate%" OR LOWER(tradeNames_list)... | [{'UUID': 'DrugTargetsIndication121923_text_843654', 'drugName': 'Ruxolitinib Phosphate', 'tradeNames_list': "['Jakafi', 'Opzelura']", 'syns_list': "['INCB-018424 PHOSPHATE', 'INCB-018424 SALT', 'INCB-18424 PHOSPHATEINCB018424 PHOSPHATE', 'INCB018424 SALT', 'OpzeluraRuxolitinib (as phosphate)', 'Ruxolitinib monophospha... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1429 | Q6 | What genes does Nicotine Polacrilex target when it's used to treat nicotine dependence? | When used to treat nicotine dependence, the drug Nicotine Polacrilex targets the genes CHRNB2 and CHRNA4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%nicotine polacrilex%" OR LOWER(tradeNames_list) L... | [{'UUID': 'DrugTargetsIndication121923_text_857247', 'drugName': 'Nicotine Polacrilex', 'tradeNames_list': "['Commit', 'Nicorette', 'Nicorette (mint)', 'Nicotine polacrilex', 'Thrive']", 'syns_list': "['Nicotine polacrilex']", 'target': 'ENSG00000160716', 'approvedSymbol': 'CHRNB2', 'approvedName': 'cholinergic recepto... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.139 | Q6 | What genes does Naloxone target when it's used to treat eating disorder? | Naloxone has not been approved by the FDA as a treatment for eating disorder, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are OPRM1, OPRK1, and OPRD1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%naloxone%" OR LOWER(tradeNames_list) LIKE "%nalox... | [{'UUID': 'DrugTargetsIndication121923_text_791489', 'drugName': 'Naloxone', 'tradeNames_list': "['Nalone', 'Narcan', 'Narcanti']", 'syns_list': "['Dbl naloxone', 'NSC-70413', 'Naloxone', 'Suboxone']", 'target': 'ENSG00000112038', 'approvedSymbol': 'OPRM1', 'approvedName': 'opioid receptor mu 1', 'mesh_heading': 'Feedi... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1191 | Q6 | What genes does Liraglutide target when it's used to treat Alzheimer disease? | Liraglutide has not been approved by the FDA as a treatment for Alzheimer disease, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is GLP1R. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%liraglutide%" OR LOWER(tradeNames_list) LIKE "%li... | [{'UUID': 'DrugTargetsIndication121923_text_1044524', 'drugName': 'Liraglutide', 'tradeNames_list': "['Saxenda', 'Victoza']", 'syns_list': "['Liraglutide', 'Liraglutide (rdna origin)', 'Liraglutide recombinantNN-2211', 'NN-9924', 'NN2211', 'NN9924', 'NNC 90-1170', 'NNC-90-1170']", 'target': 'ENSG00000112164', 'approved... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1757 | Q6 | What genes does Gabapentin target when it's used to treat autism spectrum disorder? | Gabapentin has not been approved by the FDA as a treatment for autism spectrum disorder, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are CACNA1B, CACNA1C, CACNA1S, CACNA1D, CACNA1F, CACNA2D2, CACNA2D1, CACNA1H, CACNA1G, CACNA1I, CACNA1A, CACNA2D3, CACNA2D4, C... | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%gabapentin%" OR LOWER(tradeNames_list) LIKE "%gab... | [{'UUID': 'DrugTargetsIndication121923_text_895064', 'drugName': 'Gabapentin', 'tradeNames_list': "['Gabapentin', 'Gralise', 'Neurontin']", 'syns_list': "['CI-945', 'DM-1796', 'GOE 3450', 'GOE-3450', 'Gabapentin', 'NSC-742194NSC-759254']", 'target': 'ENSG00000148408', 'approvedSymbol': 'CACNA1B', 'approvedName': 'calci... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1573 | Q6 | What genes does Venetoclax target when it's used to treat neoplasm? | When used to treat neoplasm, the drug Venetoclax targets the gene BCL2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%venetoclax%" OR LOWER(tradeNames_list) LIKE "%ven... | [{'UUID': 'DrugTargetsIndication121923_text_989844', 'drugName': 'Venetoclax', 'tradeNames_list': "['Venclexta']", 'syns_list': "['ABT-199', 'GDC-0199', 'RG-7601', 'RG7601', 'Venetoclax']", 'target': 'ENSG00000171791', 'approvedSymbol': 'BCL2', 'approvedName': 'BCL2 apoptosis regulator', 'mesh_heading': 'Neoplasms', 'e... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1443 | Q6 | What genes does Tadalafil target when it's used to treat head and neck squamous cell carcinoma? | Tadalafil has not been approved by the FDA as a treatment for head and neck squamous cell carcinoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is PDE5A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%tadalafil%" OR LOWER(tradeNames_list) LIKE "%tada... | [{'UUID': 'DrugTargetsIndication121923_text_1094077', 'drugName': 'Tadalafil', 'tradeNames_list': "['Adcirca', 'Cialis', 'Tadliq']", 'syns_list': "['IC-351', 'IC351', 'LY-450190', 'LY450190', 'NSC-750236', 'NSC-759172Tadalafil', 'Tadalafil mylan', 'Trans-tadalafil']", 'target': 'ENSG00000138735', 'approvedSymbol': 'PDE... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.836 | Q6 | What genes does Fluticasone Propionate target when it's used to treat seasonal allergic rhinitis? | When used to treat seasonal allergic rhinitis, the drug Fluticasone Propionate targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fluticasone propionate%" OR LOWER(tradeNames_list... | [{'UUID': 'DrugTargetsIndication121923_text_232532', 'drugName': 'Fluticasone Propionate', 'tradeNames_list': "['Aerivio spiromax', 'Airflusal forspiro', 'Armonair digihalerArmonair respiclick', 'Cutivate', 'Flixonase', 'Flixotide', 'FlonaseFlonase allergy relief', 'Flovent', 'Flovent diskus 100Flovent diskus 250', 'Fl... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.451 | Q6 | What genes does Bromocriptine Mesylate target when it's used to treat acromegaly? | When used to treat acromegaly, the drug Bromocriptine Mesylate targets the genes DRD2, DRD3, and DRD4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%bromocriptine mesylate%" OR LOWER(tradeNames_list... | [{'UUID': 'DrugTargetsIndication121923_text_201376', 'drugName': 'Bromocriptine Mesylate', 'tradeNames_list': "['Bromocriptine mesylate', 'Cycloset', 'Parlodel']", 'syns_list': "['2-bromoergocryptine mesylate', 'Bromocriptine mesilateBromocriptine mesylate', 'Bromocriptine methanesulfonate', 'CB-154CB-154 MESYLATE', 'C... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.849 | Q6 | What genes does Naloxone Hydrochloride target when it's used to treat septic shock? | When used to treat septic shock, the drug Naloxone Hydrochloride targets the genes OPRM1, OPRK1, and OPRD1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%naloxone hydrochloride%" OR LOWER(tradeNames_list... | [{'UUID': 'DrugTargetsIndication121923_text_789395', 'drugName': 'Naloxone Hydrochloride', 'tradeNames_list': "['Evzio', 'Evzio (autoinjector)', 'Kloxxado', 'Nalone', 'NaloxoneNaloxone hydrochloride', 'Naloxone hydrochloride (autoinjector)', 'NarcanNarcan neonatal', 'Narconil', 'Prenoxad', 'Zimhi']", 'syns_list': "['An... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1087 | Q6 | What genes does Fentanyl target when it's used to treat Chronic pain? | When used to treat Chronic pain, the drug Fentanyl targets the gene OPRM1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fentanyl%" OR LOWER(tradeNames_list) LIKE "%fenta... | [{'UUID': 'DrugTargetsIndication121923_text_787960', 'drugName': 'Fentanyl', 'tradeNames_list': "['Abstral', 'Actiq', 'Breakyl', 'Duragesic', 'Duragesic-100', 'Duragesic-12Duragesic-25', 'Duragesic-37', 'Duragesic-50', 'Duragesic-75', 'DurogesicDurogesic dtrans', 'Effentora', 'Fencino', 'Fentalis reservoirFentanyl-100'... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1420 | Q6 | What genes does Ganaxolone target when it's used to treat Seizure? | When used to treat Seizure, the drug Ganaxolone targets the genes GABRA1, GABRB2, GABRG2, GABRB3, GABRA4, GABRG3, GABRQ, GABRA3, GABRP, GABRD, GABRG1, GABRB1, GABRE, GABRA2, GABRA5, and GABRA6. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ganaxolone%" OR LOWER(tradeNames_list) LIKE "%gan... | [{'UUID': 'DrugTargetsIndication121923_text_945944', 'drugName': 'Ganaxolone', 'tradeNames_list': "['Ztalmy']", 'syns_list': "['CCD 1042', 'CCD-1042', 'DEA NO. 2401', 'Ganaxolone', 'Ztalmy']", 'target': 'ENSG00000022355', 'approvedSymbol': 'GABRA1', 'approvedName': 'gamma-aminobutyric acid type A receptor subunit alpha... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1154 | Q6 | What genes does Fostamatinib Disodium target when it's used to treat IGA glomerulonephritis? | Fostamatinib Disodium has not been approved by the FDA as a treatment for IGA glomerulonephritis, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is SYK. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fostamatinib disodium%" OR LOWER(tradeNames_list)... | [{'UUID': 'DrugTargetsIndication121923_text_848770', 'drugName': 'Fostamatinib Disodium', 'tradeNames_list': "['Tavalisse']", 'syns_list': "['Fostamatinib disodium', 'Fostamatinib disodium hexahydrateFostamatinib disodium salt hexahydrate', 'Fostamatinib sodium hydrateR-788 SODIUM', 'R-788 SODIUM HYDRATE', 'R-935788 SO... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1826 | Q6 | What genes does Amlodipine Besylate target when it's used to treat angina pectoris? | When used to treat angina pectoris, the drug Amlodipine Besylate targets the genes CACNA1C, CACNA1S, CACNA1D, and CACNA1F. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%amlodipine besylate%" OR LOWER(tradeNames_list) L... | [{'UUID': 'DrugTargetsIndication121923_text_1043685', 'drugName': 'Amlodipine Besylate', 'tradeNames_list': "['Amlodipine besylate', 'Norliqva', 'Norvasc']", 'syns_list': "['Amlodipine (as besilate)', 'Amlodipine benzenesulfonateAmlodipine besilate', 'Amlodipine besylate', 'Amlor', 'AntacalLodipressin', 'Monopina', 'NS... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.588 | Q6 | What genes does Pemetrexed Disodium target when it's used to treat salivary gland carcinoma? | Pemetrexed Disodium has not been approved by the FDA as a treatment for salivary gland carcinoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are TYMS, GART, and DHFR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%pemetrexed disodium%" OR LOWER(tradeNames_list) L... | [{'UUID': 'DrugTargetsIndication121923_text_918401', 'drugName': 'Pemetrexed Disodium', 'tradeNames_list': "['Alimta']", 'syns_list': "['LY-231514 DISODIUM SALT', 'LY231514 DISODIUM SALT', 'Pemetrexed disodiumPemetrexed disodium heptahydrate', 'Pemetrexed sodium hydratePemetrexed sodium salt']", 'target': 'ENSG00000228... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1892 | Q6 | What genes does Vorapaxar Sulfate target when it's used to treat myocardial infarction? | When used to treat myocardial infarction, the drug Vorapaxar Sulfate targets the gene F2R. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%vorapaxar sulfate%" OR LOWER(tradeNames_list) LIK... | [{'UUID': 'DrugTargetsIndication121923_text_1193354', 'drugName': 'Vorapaxar Sulfate', 'tradeNames_list': "['Zontivity']", 'syns_list': "['SCH 530348', 'SCH-530348', 'Vorapaxar sulfate']", 'target': 'ENSG00000181104', 'approvedSymbol': 'F2R', 'approvedName': 'coagulation factor II thrombin receptor', 'mesh_heading': 'M... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1970 | Q6 | What genes does Nintedanib Esylate target when it's used to treat systemic scleroderma? | When used to treat systemic scleroderma, the drug Nintedanib Esylate targets the genes KDR, FGFR1, FGFR3, FGFR2, FLT1, FLT4, PDGFRB, PDGFRA, and FGFR4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%nintedanib esylate%" OR LOWER(tradeNames_list) LI... | [{'UUID': 'DrugTargetsIndication121923_text_678477', 'drugName': 'Nintedanib Esylate', 'tradeNames_list': "['Ofev']", 'syns_list': "['Nintedanib esilate', 'Nintedanib esylate', 'Nintedanib ethanesulfonate']", 'target': 'ENSG00000128052', 'approvedSymbol': 'KDR', 'approvedName': 'kinase insert domain receptor', 'mesh_he... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.668 | Q6 | What genes does Nintedanib target when it's used to treat medullary thyroid gland carcinoma? | Nintedanib has not been approved by the FDA as a treatment for medullary thyroid gland carcinoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are KDR, FGFR1, FGFR3, FGFR2, FLT1, FLT4, PDGFRB, PDGFRA, and FGFR4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%nintedanib%" OR LOWER(tradeNames_list) LIKE "%nin... | [{'UUID': 'DrugTargetsIndication121923_text_678918', 'drugName': 'Nintedanib', 'tradeNames_list': "['Ofev', 'Vargatef']", 'syns_list': "['BIBF 1120', 'BIBF-1120', 'BIBF1120', 'Bibf-1120', 'Intedanib', 'Nintedanib']", 'target': 'ENSG00000128052', 'approvedSymbol': 'KDR', 'approvedName': 'kinase insert domain receptor', ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.442 | Q6 | What genes does Ipratropium Bromide target when it's used to treat atopic eczema? | When used to treat atopic eczema, the drug Ipratropium Bromide targets the gene CHRM3. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ipratropium bromide%" OR LOWER(tradeNames_list) L... | [{'UUID': 'DrugTargetsIndication121923_text_857475', 'drugName': 'Ipratropium Bromide', 'tradeNames_list': "['Atrovent', 'Atrovent aerocaps', 'Atrovent fte', 'Atrovent hfaAtrovent udvs', 'Ipratrop', 'Ipratrop steripoule', 'Ipratropium bromideRespontin', 'Rinatec', 'Tropiovent']", 'syns_list': "['Ipratropium bromide', '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1857 | Q6 | What genes does Sufentanil Citrate target when it's used to treat pain? | When used to treat pain, the drug Sufentanil Citrate targets the gene OPRM1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%sufentanil citrate%" OR LOWER(tradeNames_list) LI... | [{'UUID': 'DrugTargetsIndication121923_text_789341', 'drugName': 'Sufentanil Citrate', 'tradeNames_list': "['Dsuvia', 'Sufenta', 'Sufenta preservative free', 'SufentalSufentanil citrate']", 'syns_list': "['R 33800', 'R-33800', 'Sufentanil citrate', 'Sufentanil citrate cii']", 'target': 'ENSG00000112038', 'approvedSymbo... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.382 | Q6 | What genes does Fostamatinib Disodium target when it's used to treat Thrombocytopenia? | When used to treat Thrombocytopenia, the drug Fostamatinib Disodium targets the gene SYK. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fostamatinib disodium%" OR LOWER(tradeNames_list)... | [{'UUID': 'DrugTargetsIndication121923_text_848772', 'drugName': 'Fostamatinib Disodium', 'tradeNames_list': "['Tavalisse']", 'syns_list': "['Fostamatinib disodium', 'Fostamatinib disodium hexahydrateFostamatinib disodium salt hexahydrate', 'Fostamatinib sodium hydrateR-788 SODIUM', 'R-788 SODIUM HYDRATE', 'R-935788 SO... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1478 | Q6 | What genes does Roflumilast target when it's used to treat non-alcoholic fatty liver disease? | Roflumilast has not been approved by the FDA as a treatment for non-alcoholic fatty liver disease, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are PDE4A, PDE4D, PDE4B, and PDE4C. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%roflumilast%" OR LOWER(tradeNames_list) LIKE "%ro... | [{'UUID': 'DrugTargetsIndication121923_text_695480', 'drugName': 'Roflumilast', 'tradeNames_list': "['Daliresp', 'Daxas', 'Zoryve']", 'syns_list': "['Arq-151', 'B-9302-107', 'B9302-107', 'BY-217', 'BY217', 'BYK-20869BYK20869', 'Roflumilast', 'Zoryve']", 'target': 'ENSG00000065989', 'approvedSymbol': 'PDE4A', 'approvedN... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.974 | Q6 | What genes does Erdafitinib target when it's used to treat urinary bladder cancer? | When used to treat urinary bladder cancer, the drug Erdafitinib targets the genes FGFR1, FGFR3, FGFR2, and FGFR4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%erdafitinib%" OR LOWER(tradeNames_list) LIKE "%er... | [{'UUID': 'DrugTargetsIndication121923_text_707177', 'drugName': 'Erdafitinib', 'tradeNames_list': "['Balversa']", 'syns_list': "['Erdafitinib', 'JNJ-42756493', 'Jnj-42756493']", 'target': 'ENSG00000077782', 'approvedSymbol': 'FGFR1', 'approvedName': 'fibroblast growth factor receptor 1', 'mesh_heading': 'Urinary Bladd... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1210 | Q6 | What genes does Lutetium Dotatate Lu-177 target when it's used to treat neuroblastoma? | Lutetium Dotatate Lu-177 has not been approved by the FDA as a treatment for neuroblastoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are SSTR5, SSTR2, SSTR3, SSTR1, and SSTR4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lutetium dotatate lu-177%" OR LOWER(tradeNames_li... | [{'UUID': 'DrugTargetsIndication121923_text_1041956', 'drugName': 'Lutetium Dotatate Lu-177', 'tradeNames_list': "['Lutathera']", 'syns_list': "['(177)lu-dotatate', '177lu-dota-tyr3-octreotate', '177lu-dotatateDota-octreotate lutetium lu-177', 'Dotatate lutenium lu-177Dotatate lutetium lu-177', 'Lutetium (177lu) dotata... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.318 | Q6 | What genes does Imiquimod target when it's used to treat ependymoma? | Imiquimod has not been approved by the FDA as a treatment for ependymoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is TLR7. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%imiquimod%" OR LOWER(tradeNames_list) LIKE "%imiq... | [{'UUID': 'DrugTargetsIndication121923_text_919742', 'drugName': 'Imiquimod', 'tradeNames_list': "['Aldara', 'Imiquimod', 'Zyclara']", 'syns_list': "['Aldara', 'Imiquimod', 'NSC-369100', 'NSC-759651', 'R-837', 'S-26308', 'S26308Tmx-101']", 'target': 'ENSG00000196664', 'approvedSymbol': 'TLR7', 'approvedName': 'toll lik... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.698 | Q6 | What genes does Eribulin Mesylate target when it's used to treat breast carcinoma? | When used to treat breast carcinoma, the drug Eribulin Mesylate targets the genes TUBB4B, TUBB1, TUBA3C, TUBA4A, TUBB3, TUBA1A, TUBB4A, TUBB8, TUBB, TUBA1B, TUBA1C, TUBA3E, TUBB2A, TUBB2B, and TUBB6. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%eribulin mesylate%" OR LOWER(tradeNames_list) LIK... | [{'UUID': 'DrugTargetsIndication121923_text_147347', 'drugName': 'Eribulin Mesylate', 'tradeNames_list': "['Halaven']", 'syns_list': "['E-7389', 'E7389', 'Eribulin (as mesylate)', 'Eribulin mesilateEribulin mesylate', 'Eribulin monomethanesulfonate', 'Halaven']", 'target': 'ENSG00000196230', 'approvedSymbol': 'TUBB', '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1505 | Q6 | What genes does Regorafenib target when it's used to treat neoplasm? | When used to treat neoplasm, the drug Regorafenib targets the genes KDR, FGFR1, FGFR2, ABL1, BRAF, TEK, FLT1, KIT, FLT4, PDGFRB, PDGFRA, RAF1, EPHA2, FRK, NTRK1, RET, DDR2, and MAPK11. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%regorafenib%" OR LOWER(tradeNames_list) LIKE "%re... | [{'UUID': 'DrugTargetsIndication121923_text_664423', 'drugName': 'Regorafenib', 'tradeNames_list': "['Stivarga']", 'syns_list': "['BAY 73-4506', 'BAY 73-4506 monohydrate', 'BAY-73-4506', 'BAY-734506Regorafenib', 'Regorafenib anhydrous', 'Regorafenib hydrateRegorafenib monohydrate']", 'target': 'ENSG00000066468', 'appro... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.430 | Q6 | What genes does Prednisone target when it's used to treat autoimmune thrombocytopenic purpura? | When used to treat autoimmune thrombocytopenic purpura, the drug Prednisone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%prednisone%" OR LOWER(tradeNames_list) LIKE "%pre... | [{'UUID': 'DrugTargetsIndication121923_text_218692', 'drugName': 'Prednisone', 'tradeNames_list': "['Cortan', 'Cortancyl', 'Decortisyl', 'Delta-dome', 'Deltasone', 'FernisoneLiquid pred', 'Lodotra', 'Meticorten', 'Orasone', 'Paracort', 'Prednicen-mPrednisone', 'Prednisone intensol', 'Rayos', 'Servisone', 'Sterapred']",... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.601 | Q6 | What genes does Memantine Hydrochloride target when it's used to treat Alzheimer disease? | When used to treat Alzheimer disease, the drug Memantine Hydrochloride targets the genes GRIN1, GRIN2A, GRIN2B, GRIN2D, GRIN3B, GRIN2C, and GRIN3A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%memantine hydrochloride%" OR LOWER(tradeNames_lis... | [{'UUID': 'DrugTargetsIndication121923_text_455064', 'drugName': 'Memantine Hydrochloride', 'tradeNames_list': "['Akatinol', 'Ebixa', 'Marixino', 'Memantine', 'Memantine hydrochlorideNamenda', 'Namenda xr', 'Nemdatine', 'Valios']", 'syns_list': "['Acrescent', 'Auxura', 'Balaxur', 'FP-01', 'Memantine accord', 'Memantine... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1964 | Q6 | What genes does Everolimus target when it's used to treat breast cancer? | When used to treat breast cancer, the drug Everolimus targets the gene FKBP1A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%everolimus%" OR LOWER(tradeNames_list) LIKE "%eve... | [{'UUID': 'DrugTargetsIndication121923_text_1087129', 'drugName': 'Everolimus', 'tradeNames_list': "['Afinitor', 'Afinitor disperz', 'Certican', 'Votubia', 'Zortress']", 'syns_list': "['40-o-(2-hydroxyethyl)-rapamycin', 'Everolimus', 'RAD 666', 'RAD-001RAD-666', 'RAD001', 'SDZ-RAD', 'Sdz rad']", 'target': 'ENSG00000088... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.629 | Q6 | What genes does Triamcinolone Acetonide target when it's used to treat bursitis? | When used to treat bursitis, the drug Triamcinolone Acetonide targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%triamcinolone acetonide%" OR LOWER(tradeNames_lis... | [{'UUID': 'DrugTargetsIndication121923_text_222019', 'drugName': 'Triamcinolone Acetonide', 'tradeNames_list': "['Adcortyl', 'Adcortyl in orabase', 'Allernaze', 'Aristocort', 'Aristocort aAristogel', 'Audicort', 'Aureocort', 'Azmacort', 'Flutex', 'Gppe ear dps capGppe ear oint', 'Kenacort', 'Kenalog', 'Kenalog in oraba... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1170 | Q6 | What genes does Triamcinolone Acetonide target when it's used to treat type III hypersensitivity reaction disease? | When used to treat type III hypersensitivity reaction disease, the drug Triamcinolone Acetonide targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%triamcinolone acetonide%" OR LOWER(tradeNames_lis... | [{'UUID': 'DrugTargetsIndication121923_text_222207', 'drugName': 'Triamcinolone Acetonide', 'tradeNames_list': "['Adcortyl', 'Adcortyl in orabase', 'Allernaze', 'Aristocort', 'Aristocort aAristogel', 'Audicort', 'Aureocort', 'Azmacort', 'Flutex', 'Gppe ear dps capGppe ear oint', 'Kenacort', 'Kenalog', 'Kenalog in oraba... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1254 | Q6 | What genes does Lisdexamfetamine Dimesylate target when it's used to treat schizophrenia? | Lisdexamfetamine Dimesylate has not been approved by the FDA as a treatment for schizophrenia, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are SLC6A2, SLC18A2, and SLC6A3. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lisdexamfetamine dimesylate%" OR LOWER(tradeNames... | [{'UUID': 'DrugTargetsIndication121923_text_419190', 'drugName': 'Lisdexamfetamine Dimesylate', 'tradeNames_list': "['Elvanse', 'Elvanse adult', 'Vyvanse']", 'syns_list': "['Lisdexamfetamine dimesilate', 'Lisdexamfetamine dimesylateLisdexamfetamine dimethanesulfonate', 'Lisdexamfetamine mesilateLisdexamphetamine dimesi... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.230 | Q6 | What genes does Phenylephrine Hydrochloride target when it's used to treat Pruritus? | When used to treat Pruritus, the drug Phenylephrine Hydrochloride targets the genes ADRA1A, ADRA1D, and ADRA1B. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%phenylephrine hydrochloride%" OR LOWER(tradeNames... | [{'UUID': 'DrugTargetsIndication121923_text_416697', 'drugName': 'Phenylephrine Hydrochloride', 'tradeNames_list': "['Afrin 4 hour nasal spray', 'Biomydrin', 'Biorphen', 'Fenilfar', 'FenoxMydfrin', 'Nazex', 'Neo-synephrine', 'Neosynephrine', 'NostrilNurofen sinus pain relief', 'Phenylephrine hydrochloride', 'PrefrinVaz... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1180 | Q6 | What genes does Budesonide target when it's used to treat Nasal congestion? | When used to treat Nasal congestion, the drug Budesonide targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%budesonide%" OR LOWER(tradeNames_list) LIKE "%bud... | [{'UUID': 'DrugTargetsIndication121923_text_222609', 'drugName': 'Budesonide', 'tradeNames_list': "['Aircort', 'Budeflam aquanase', 'Budelin novolizer', 'BudenofalkBudesonide', 'Cortiment', 'Duoresp spiromax', 'Entocort', 'Entocort crEntocort ec', 'Ortikos', 'Preferid', 'Pulmaxan', 'PulmicortPulmicort flexhaler', 'Pulm... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1332 | Q6 | What genes does Vorinostat target when it's used to treat T-cell non-Hodgkin lymphoma? | When used to treat T-cell non-Hodgkin lymphoma, the drug Vorinostat targets the genes HDAC1, HDAC3, HDAC6, and HDAC2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%vorinostat%" OR LOWER(tradeNames_list) LIKE "%vor... | [{'UUID': 'DrugTargetsIndication121923_text_1077140', 'drugName': 'Vorinostat', 'tradeNames_list': "['Zolinza']", 'syns_list': "['MK-0683', 'MK0683', 'NSC-701852', 'NSC-748799', 'NSC-759852Suberoylanilide hydroxamic acid', 'Vorinostat']", 'target': 'ENSG00000116478', 'approvedSymbol': 'HDAC1', 'approvedName': 'histone ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1587 | Q6 | What genes does Amantadine Hydrochloride target when it's used to treat Parkinson disease? | When used to treat Parkinson disease, the drug Amantadine Hydrochloride targets the genes GRIN1, GRIN2A, GRIN2B, GRIN2D, GRIN3B, GRIN2C, and GRIN3A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%amantadine hydrochloride%" OR LOWER(tradeNames_li... | [{'UUID': 'DrugTargetsIndication121923_text_441038', 'drugName': 'Amantadine Hydrochloride', 'tradeNames_list': "['Amantadine hydrochloride', 'Gocovri', 'Lysovir', 'Mantadine', 'Osmolex erSymadine', 'Symmetrel']", 'syns_list': "['Adamantanamine hydrochloride', 'Amantadine hclAmantadine hydrochloride', 'EXP-105-1', 'Man... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.69 | Q6 | What genes does Clonidine target when it's used to treat glaucoma? | When used to treat glaucoma, the drug Clonidine targets the genes ADRA2A, ADRA2C, and ADRA2B. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%clonidine%" OR LOWER(tradeNames_list) LIKE "%clon... | [{'UUID': 'DrugTargetsIndication121923_text_1033829', 'drugName': 'Clonidine', 'tradeNames_list': "['Catapres', 'Catapres-tts-1', 'Catapres-tts-2', 'Catapres-tts-3', 'ClonidineNexiclon xr']", 'syns_list': "['Catapres', 'Catarpres-tts', 'Clonidine', 'Clonidine extended releaseClorpres', 'Combipres', 'Duraclon', 'ST-155-... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.25 | Q6 | What genes does Prednisone target when it's used to treat lymphoplasmacytic lymphoma? | Prednisone has not been approved by the FDA as a treatment for lymphoplasmacytic lymphoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%prednisone%" OR LOWER(tradeNames_list) LIKE "%pre... | [{'UUID': 'DrugTargetsIndication121923_text_218645', 'drugName': 'Prednisone', 'tradeNames_list': "['Cortan', 'Cortancyl', 'Decortisyl', 'Delta-dome', 'Deltasone', 'FernisoneLiquid pred', 'Lodotra', 'Meticorten', 'Orasone', 'Paracort', 'Prednicen-mPrednisone', 'Prednisone intensol', 'Rayos', 'Servisone', 'Sterapred']",... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.147 | Q6 | What genes does Tofacitinib Citrate target when it's used to treat psoriatic arthritis? | When used to treat psoriatic arthritis, the drug Tofacitinib Citrate targets the genes JAK1, JAK3, TYK2, and JAK2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%tofacitinib citrate%" OR LOWER(tradeNames_list) L... | [{'UUID': 'DrugTargetsIndication121923_text_848325', 'drugName': 'Tofacitinib Citrate', 'tradeNames_list': "['Xeljanz', 'Xeljanz xr']", 'syns_list': "['CP-690,550-10', 'CP-690550-10', 'Cp-690550 citrate', 'Tasocitinib citrateTasocitinib monocitrate', 'Tofacitinib citrate', 'Tofacitinib monocitrate']", 'target': 'ENSG00... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.542 | Q6 | What genes does Desoximetasone target when it's used to treat psoriasis? | When used to treat psoriasis, the drug Desoximetasone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%desoximetasone%" OR LOWER(tradeNames_list) LIKE "... | [{'UUID': 'DrugTargetsIndication121923_text_220822', 'drugName': 'Desoximetasone', 'tradeNames_list': "['Desoximetasone', 'Stiedex', 'Stiedex lp', 'Stiedex lpn', 'TopicortTopicort lp']", 'syns_list': "['A-41-304', 'A-41304', 'Desoximetasone', 'Desoxymethasone', 'HOE 304HOE-304', 'J83.644C', 'NSC-759189', 'R 2113', 'R-2... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.818 | Q6 | What genes does Irinotecan Hydrochloride target when it's used to treat gastrointestinal stromal tumor? | Irinotecan Hydrochloride has not been approved by the FDA as a treatment for gastrointestinal stromal tumor, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is TOP1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%irinotecan hydrochloride%" OR LOWER(tradeNames_li... | [{'UUID': 'DrugTargetsIndication121923_text_941136', 'drugName': 'Irinotecan Hydrochloride', 'tradeNames_list': "['Campto', 'Camptosar', 'Irinotecan hydrochloride', 'Onivyde']", 'syns_list': "['CPT-11', 'DQ-2805', 'Irinotecan hydrochlorideIrinotecan hydrochloride anhydrous', 'Irinotecan hydrochloride hydrateIrinotecan ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1120 | Q6 | What genes does Dexamethasone target when it's used to treat contact dermatitis? | When used to treat contact dermatitis, the drug Dexamethasone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dexamethasone%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_227768', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.88 | Q6 | What genes does Mavacamten target when it's used to treat hypertrophic cardiomyopathy? | When used to treat hypertrophic cardiomyopathy, the drug Mavacamten targets the genes MYH7, MYH6, MYH7B, MYL3, MYL2, MYL7, and MYL4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%mavacamten%" OR LOWER(tradeNames_list) LIKE "%mav... | [{'UUID': 'DrugTargetsIndication121923_text_1053253', 'drugName': 'Mavacamten', 'tradeNames_list': "['Camzyos']", 'syns_list': "['Camzyos', 'MYK-461', 'Mavacamten', 'Myk-461', 'SAR-439152']", 'target': 'ENSG00000092054', 'approvedSymbol': 'MYH7', 'approvedName': 'myosin heavy chain 7', 'mesh_heading': 'Cardiomyopathy, ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1183 | Q6 | What genes does Darolutamide target when it's used to treat prostate adenocarcinoma? | When used to treat prostate adenocarcinoma, the drug Darolutamide targets the gene AR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%darolutamide%" OR LOWER(tradeNames_list) LIKE "%d... | [{'UUID': 'DrugTargetsIndication121923_text_924424', 'drugName': 'Darolutamide', 'tradeNames_list': "['Nubeqa']", 'syns_list': "['BAY 1841788', 'BAY-1841788', 'BAY1841788', 'Darolutamide', 'ODM-201Odm-201']", 'target': 'ENSG00000169083', 'approvedSymbol': 'AR', 'approvedName': 'androgen receptor', 'mesh_heading': 'Pros... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1333 | Q6 | What genes does Bosutinib target when it's used to treat breast carcinoma? | Bosutinib has not been approved by the FDA as a treatment for breast carcinoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are ABL1, BCR, HCK, SRC, and LYN. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%bosutinib%" OR LOWER(tradeNames_list) LIKE "%bosu... | [{'UUID': 'DrugTargetsIndication121923_text_710987', 'drugName': 'Bosutinib', 'tradeNames_list': "['Bosulif']", 'syns_list': "['Bosutinib', 'Bosutinib (as monohydrate)', 'Bosutinib hydrateBosutinib monohydrate', 'SK-606', 'SKI-606']", 'target': 'ENSG00000097007', 'approvedSymbol': 'ABL1', 'approvedName': 'ABL proto-onc... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1806 | Q6 | What genes does Octreotide Acetate target when it's used to treat thymus neoplasm? | Octreotide Acetate has not been approved by the FDA as a treatment for thymus neoplasm, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are SSTR5, SSTR2, SSTR3, SSTR1, and SSTR4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%octreotide acetate%" OR LOWER(tradeNames_list) LI... | [{'UUID': 'DrugTargetsIndication121923_text_1042108', 'drugName': 'Octreotide Acetate', 'tradeNames_list': "['Bynfezia pen', 'Mycapssa', 'Octreotide acetateOctreotide acetate (preservative free)Octreotide acetate preservative free', 'Sandostatin', 'Sandostatin lar']", 'syns_list': "['Octreolin', 'Octreotide (as acetate... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1819 | Q6 | What genes does Sotorasib target when it's used to treat neoplasm? | When used to treat neoplasm, the drug Sotorasib targets the gene KRAS. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%sotorasib%" OR LOWER(tradeNames_list) LIKE "%soto... | [{'UUID': 'DrugTargetsIndication121923_text_1193506', 'drugName': 'Sotorasib', 'tradeNames_list': "['Lumakras']", 'syns_list': "['AMG-510', 'AMG510', 'Kras g12c inhibitor 9Kras mutant-targeting amg 510', 'Sotorasib']", 'target': 'ENSG00000133703', 'approvedSymbol': 'KRAS', 'approvedName': 'KRAS proto-oncogene, GTPase',... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1374 | Q6 | What genes does Sitagliptin Phosphate target when it's used to treat hyperlipidemia? | When used to treat hyperlipidemia, the drug Sitagliptin Phosphate targets the gene DPP4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%sitagliptin phosphate%" OR LOWER(tradeNames_list)... | [{'UUID': 'DrugTargetsIndication121923_text_933073', 'drugName': 'Sitagliptin Phosphate', 'tradeNames_list': "['Janumet Xr', 'Januvia']", 'syns_list': "['Glactiv', 'MK-0431', 'MK0431', 'ONO-5435', 'Sitagliptin monophosphateSitagliptin monophosphate anhydrousSitagliptin monophosphate monohydrate', 'Sitagliptin phosphate... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1144 | Q6 | What genes does Ipratropium Bromide target when it's used to treat asthma? | When used to treat asthma, the drug Ipratropium Bromide targets the gene CHRM3. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ipratropium bromide%" OR LOWER(tradeNames_list) L... | [{'UUID': 'DrugTargetsIndication121923_text_857481', 'drugName': 'Ipratropium Bromide', 'tradeNames_list': "['Atrovent', 'Atrovent aerocaps', 'Atrovent fte', 'Atrovent hfaAtrovent udvs', 'Ipratrop', 'Ipratrop steripoule', 'Ipratropium bromideRespontin', 'Rinatec', 'Tropiovent']", 'syns_list': "['Ipratropium bromide', '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.367 | Q6 | What genes does Azacitidine target when it's used to treat non-Hodgkins lymphoma? | Azacitidine has not been approved by the FDA as a treatment for non-Hodgkins lymphoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are DNMT1 and DNMT3A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%azacitidine%" OR LOWER(tradeNames_list) LIKE "%az... | [{'UUID': 'DrugTargetsIndication121923_text_1191929', 'drugName': 'Azacitidine', 'tradeNames_list': "['Azacitidine', 'Onureg', 'Vidaza']", 'syns_list': "['5-azacitidine', 'Azacitidine', 'Ladakamycin', 'NSC-102816', 'U-18,496U-18496', 'Vidaza']", 'target': 'ENSG00000130816', 'approvedSymbol': 'DNMT1', 'approvedName': 'D... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1790 | Q6 | What genes does Bortezomib target when it's used to treat Mantle cell lymphoma? | When used to treat Mantle cell lymphoma, the drug Bortezomib targets the genes PSMD1, PSMB2, PSMB1, PSMB5, PSMB8, PSMB9, PSMB6, PSMD14, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMA7, PSMA8, PSMB10, PSMB11, PSMB3, PSMB4, PSMB7, ADRM1, PSMC2, PSMC1, PSMC4, PSMC6, PSMC3, PSMC5, PSMD2, PSMD3, PSMD12, PSMD11, PSMD6, PSMD7... | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%bortezomib%" OR LOWER(tradeNames_list) LIKE "%bor... | [{'UUID': 'DrugTargetsIndication121923_text_342347', 'drugName': 'Bortezomib', 'tradeNames_list': "['Velcade']", 'syns_list': "['Bortezomib', 'Bortezomib accord', 'Bortezomib hydrate', 'LDP-341NSC-681239', 'PS-341', 'Velcade']", 'target': 'ENSG00000126067', 'approvedSymbol': 'PSMB2', 'approvedName': 'proteasome 20S sub... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1208 | Q6 | What genes does Glucagon target when it's used to treat Hypoglycemia? | When used to treat Hypoglycemia, the drug Glucagon targets the gene GCGR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%glucagon%" OR LOWER(tradeNames_list) LIKE "%gluca... | [{'UUID': 'DrugTargetsIndication121923_text_968350', 'drugName': 'Dasiglucagon Hydrochloride', 'tradeNames_list': "['Zegalogue', 'Zegalogue (autoinjector)']", 'syns_list': "['Dasiglucagon hydrochloride']", 'target': 'ENSG00000215644', 'approvedSymbol': 'GCGR', 'approvedName': 'glucagon receptor', 'mesh_heading': 'Hypog... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1035 | Q6 | What genes does Fluticasone Furoate target when it's used to treat Nasal congestion? | When used to treat Nasal congestion, the drug Fluticasone Furoate targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fluticasone furoate%" OR LOWER(tradeNames_list) L... | [{'UUID': 'DrugTargetsIndication121923_text_225657', 'drugName': 'Fluticasone Furoate', 'tradeNames_list': "['Arnuity ellipta', 'Avamys', 'Flonase sensimist allergy reliefRelvar ellipta', 'Trelegy ellipta', 'Veramyst']", 'syns_list': "['Allermist', 'Ennhale', 'Fluticasone furoate', 'Furamist', 'GSK 685 698GSK-685968', ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1039 | Q6 | What genes does Midazolam target when it's used to treat nicotine dependence? | Midazolam has not been approved by the FDA as a treatment for nicotine dependence, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are GABRA1, GABRB2, GABRG2, GABRB3, GABRA4, GABRG3, GABRQ, GABRA3, GABRP, GABRD, GABRG1, GABRB1, GABRE, GABRA2, GABRA5, and GABRA6. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%midazolam%" OR LOWER(tradeNames_list) LIKE "%mida... | [{'UUID': 'DrugTargetsIndication121923_text_948988', 'drugName': 'Midazolam', 'tradeNames_list': "['Midazolam in 0.8% sodium chloride', 'Midazolam in 0.9% sodium chlorideNayzilam']", 'syns_list': "['Midazolam', 'Midazolam civ', 'USL-261', 'USL261']", 'target': 'ENSG00000022355', 'approvedSymbol': 'GABRA1', 'approvedNam... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1761 | Q6 | What genes does Naproxen target when it's used to treat Arthralgia? | When used to treat Arthralgia, the drug Naproxen targets the genes PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%naproxen%" OR LOWER(tradeNames_list) LIKE "%napro... | [{'UUID': 'DrugTargetsIndication121923_text_838532', 'drugName': 'Naproxen', 'tradeNames_list': "['Aleve', 'Anaprox', 'Arthrosin 250', 'Arthrosin 250 ec', 'Arthrosin 500Arthrosin 500 ec', 'Condrotec', 'Ec-naprosyn', 'Equiproxen', 'Feminax ultraGrenoxal', 'Kenosyn', 'Laraflex', 'Napratec op', 'Naprosyn', 'Naprosyn 375Na... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1357 | Q6 | What genes does Enzalutamide target when it's used to treat prostate carcinoma? | When used to treat prostate carcinoma, the drug Enzalutamide targets the gene AR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%enzalutamide%" OR LOWER(tradeNames_list) LIKE "%e... | [{'UUID': 'DrugTargetsIndication121923_text_921127', 'drugName': 'Enzalutamide', 'tradeNames_list': "['Xtandi']", 'syns_list': "['Enzalutamide', 'MDV-3100', 'MDV3100', 'Mdv 3100']", 'target': 'ENSG00000169083', 'approvedSymbol': 'AR', 'approvedName': 'androgen receptor', 'mesh_heading': 'Prostatic Neoplasms', 'efo_term... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1875 | Q6 | What genes does Dexamethasone target when it's used to treat inflammation? | When used to treat inflammation, the drug Dexamethasone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dexamethasone%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_226915', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.672 | Q6 | What genes does Imatinib Mesylate target when it's used to treat graft versus host disease? | Imatinib Mesylate has not been approved by the FDA as a treatment for graft versus host disease, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are ABL1, BCR, KIT, and PDGFRB. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%imatinib mesylate%" OR LOWER(tradeNames_list) LIK... | [{'UUID': 'DrugTargetsIndication121923_text_743524', 'drugName': 'Imatinib Mesylate', 'tradeNames_list': "['Gleevec', 'Glivec', 'Imatinib mesylate']", 'syns_list': "['Gleevec', 'Imatinib (as mesilate)', 'Imatinib accord', 'Imatinib medacImatinib mesilate', 'Imatinib mesylate', 'Imatinib methane sulfonateImatinib methan... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.369 | Q6 | What genes does Lisinopril target when it's used to treat heart failure? | When used to treat heart failure, the drug Lisinopril targets the gene ACE. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lisinopril%" OR LOWER(tradeNames_list) LIKE "%lis... | [{'UUID': 'DrugTargetsIndication121923_text_1091692', 'drugName': 'Lisinopril', 'tradeNames_list': "['Acemin', 'Carace', 'Lisinopril', 'Lisopress', 'Prinivil', 'Qbrelis', 'Zestril']", 'syns_list': "['Lisinopril', 'Lisinopril dihydrate', 'Lisinopril hydrate', 'MK-521Ranolip']", 'target': 'ENSG00000159640', 'approvedSymb... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.80 | Q6 | What genes does Bupivacaine target when it's used to treat Breech presentation? | Bupivacaine has not been approved by the FDA as a treatment for Breech presentation, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is SCN4A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%bupivacaine%" OR LOWER(tradeNames_list) LIKE "%bu... | [{'UUID': 'DrugTargetsIndication121923_text_663103', 'drugName': 'Bupivacaine', 'tradeNames_list': "['Anekain', 'Exparel', 'Marcaine', 'Posimir', 'Sensorcaine']", 'syns_list': "['Bucaine', 'Bupivacaine', 'Bupivacaine liposome', 'LIQ-865', 'LIQ865Liposomal bupivacaine', 'MarcaineRopivacaine hydrochloride impurity, bupiv... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.28 | Q6 | What genes does Selexipag target when it's used to treat Recurrent thrombophlebitis? | When used to treat Recurrent thrombophlebitis, the drug Selexipag targets the gene PTGIR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%selexipag%" OR LOWER(tradeNames_list) LIKE "%sele... | [{'UUID': 'DrugTargetsIndication121923_text_246143', 'drugName': 'Selexipag', 'tradeNames_list': "['Uptravi']", 'syns_list': "['ACT-293987', 'NS-304', 'Selexipag']", 'target': 'ENSG00000160013', 'approvedSymbol': 'PTGIR', 'approvedName': 'prostaglandin I2 receptor', 'mesh_heading': 'Thrombosis', 'efo_term': 'Recurrent ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1438 | Q6 | What genes does Mometasone Furoate target when it's used to treat asthma? | When used to treat asthma, the drug Mometasone Furoate targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%mometasone furoate%" OR LOWER(tradeNames_list) LI... | [{'UUID': 'DrugTargetsIndication121923_text_242044', 'drugName': 'Mometasone Furoate', 'tradeNames_list': "['Asmanex', 'Asmanex hfa', 'Asmanex twisthaler', 'EloconMometasone furoate', 'Nasonex', 'Nasonex 24hr allergy', 'Sinuva']", 'syns_list': "['LAS-41002', 'LAS41002', 'LYR-210', 'LYR210', 'Lyr-210', 'MometasoneMometa... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.531 | Q6 | What genes does Methotrexate target when it's used to treat lymphoblastic lymphoma? | When used to treat lymphoblastic lymphoma, the drug Methotrexate targets the gene DHFR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%methotrexate%" OR LOWER(tradeNames_list) LIKE "%m... | [{'UUID': 'DrugTargetsIndication121923_text_1064361', 'drugName': 'Methotrexate', 'tradeNames_list': "['Amethopterin', 'Ebetrex', 'Emtexate high-pot', 'Emtexate pf', 'FolexMaxtrex', 'Methotrexate', 'Metoject', 'Mexate', 'Otrexup', 'Otrexup pfsRasuvo', 'Reditrex', 'Rheumatrex', 'Trexall', 'Zlatal']", 'syns_list': "['(r)... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1836 | Q6 | What genes does Aspirin target when it's used to treat Recurrent thrombophlebitis? | When used to treat Recurrent thrombophlebitis, the drug Aspirin targets the genes PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%aspirin%" OR LOWER(tradeNames_list) LIKE "%aspiri... | [{'UUID': 'DrugTargetsIndication121923_text_834429', 'drugName': 'Aspirin', 'tradeNames_list': "['8-hour bayer', 'Acetosalic Acid', 'Acetylsalic acidAcetylsalicylic Acid', 'Alka rapid', 'Anadin all night', 'Angettes 75Aspirin', 'Aspro clr', 'Bayer extra strength aspirin for migraine painDanamep', 'Disprin cv', 'Disprin... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.56 | Q6 | What genes does Gabapentin target when it's used to treat dyspepsia? | Gabapentin has not been approved by the FDA as a treatment for dyspepsia, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are CACNA1B, CACNA1C, CACNA1S, CACNA1D, CACNA1F, CACNA2D2, CACNA2D1, CACNA1H, CACNA1G, CACNA1I, CACNA1A, CACNA2D3, CACNA2D4, CACNA1E, CACNB4,... | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%gabapentin%" OR LOWER(tradeNames_list) LIKE "%gab... | [{'UUID': 'DrugTargetsIndication121923_text_895050', 'drugName': 'Gabapentin', 'tradeNames_list': "['Gabapentin', 'Gralise', 'Neurontin']", 'syns_list': "['CI-945', 'DM-1796', 'GOE 3450', 'GOE-3450', 'Gabapentin', 'NSC-742194NSC-759254']", 'target': 'ENSG00000148408', 'approvedSymbol': 'CACNA1B', 'approvedName': 'calci... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.645 | Q6 | What genes does Fludarabine Phosphate target when it's used to treat Thalassemia? | Fludarabine Phosphate has not been approved by the FDA as a treatment for Thalassemia, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are POLA1, POLD4, POLD3, POLD1, POLD2, POLE, POLA2, PRIM1, PRIM2, POLE2, POLE3, RRM1, RRM2B, and RRM2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fludarabine phosphate%" OR LOWER(tradeNames_list)... | [{'UUID': 'DrugTargetsIndication121923_text_754164', 'drugName': 'Fludarabine Phosphate', 'tradeNames_list': "['Fludara', 'Fludarabine phosphate', 'Oforta']", 'syns_list': '[\'2-f-ara-amp\', \'2-f-araa\', \'2-fluoro ara-a\', \'2-fluorovidarabineFludarabine\', "Fludarabine 5\'-monophosphateFludarabine monophosphateFluda... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.306 | Q6 | What genes does Pregabalin target when it's used to treat Dementia? | Pregabalin has not been approved by the FDA as a treatment for Dementia, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are CACNA1B, CACNA1C, CACNA1S, CACNA1D, CACNA1F, CACNA2D2, CACNA2D1, CACNA1H, CACNA1G, CACNA1I, CACNA1A, CACNA2D3, CACNA2D4, CACNA1E, CACNB4, ... | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%pregabalin%" OR LOWER(tradeNames_list) LIKE "%pre... | [{'UUID': 'DrugTargetsIndication121923_text_859556', 'drugName': 'Pregabalin', 'tradeNames_list': "['Alzain', 'Axalid', 'Lecaent', 'Lyrica', 'Lyrica cr', 'Pregabalin', 'Rewisca']", 'syns_list': "['CI-1008', 'NSC-759256', 'PD-144723', 'Pregabalin', 'Pregabalin mylanPregabalin sandoz', 'Pregabalin sandoz gmbh', 'Pregabal... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.725 | Q6 | What genes does Diroximel Fumarate target when it's used to treat immune system disease? | When used to treat immune system disease, the drug Diroximel Fumarate targets the gene KEAP1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%diroximel fumarate%" OR LOWER(tradeNames_list) LI... | [{'UUID': 'DrugTargetsIndication121923_text_1055622', 'drugName': 'Diroximel Fumarate', 'tradeNames_list': "['Vumerity']", 'syns_list': "['ALKS 8700', 'ALKS-8700', 'ALKS8700', 'Alks 8700', 'BIIB-098', 'BIIB098Diroximel fumarate', 'RDC-5108', 'RDC5108']", 'target': 'ENSG00000079999', 'approvedSymbol': 'KEAP1', 'approved... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.631 | Q6 | What genes does Trazodone Hydrochloride target when it's used to treat major depressive disorder? | When used to treat major depressive disorder, the drug Trazodone Hydrochloride targets the genes HTR2C, HTR2A, and SLC6A4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%trazodone hydrochloride%" OR LOWER(tradeNames_lis... | [{'UUID': 'DrugTargetsIndication121923_text_155417', 'drugName': 'Trazodone Hydrochloride', 'tradeNames_list': "['Desyrel', 'Molipaxin', 'Molipaxin cr', 'Oleptro', 'Trazodone hydrochlorideTrialodine']", 'syns_list': "['AF-1161', 'NSC-292811', 'Trazodone hcl', 'Trazodone hydrochloride']", 'target': 'ENSG00000147246', 'a... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.8 | Q6 | What genes does Dexamethasone target when it's used to treat sinus histiocytosis with massive lymphadenopathy? | Dexamethasone has not been approved by the FDA as a treatment for sinus histiocytosis with massive lymphadenopathy, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dexamethasone%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_227612', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.810 | Q6 | What genes does Tadalafil target when it's used to treat benign prostatic hyperplasia? | When used to treat benign prostatic hyperplasia, the drug Tadalafil targets the gene PDE5A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%tadalafil%" OR LOWER(tradeNames_list) LIKE "%tada... | [{'UUID': 'DrugTargetsIndication121923_text_1094100', 'drugName': 'Tadalafil', 'tradeNames_list': "['Adcirca', 'Cialis', 'Tadliq']", 'syns_list': "['IC-351', 'IC351', 'LY-450190', 'LY450190', 'NSC-750236', 'NSC-759172Tadalafil', 'Tadalafil mylan', 'Trans-tadalafil']", 'target': 'ENSG00000138735', 'approvedSymbol': 'PDE... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1058 | Q6 | What genes does Fludarabine Phosphate target when it's used to treat myelofibrosis? | Fludarabine Phosphate has not been approved by the FDA as a treatment for myelofibrosis, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are POLA1, POLD4, POLD3, POLD1, POLD2, POLE, POLA2, PRIM1, PRIM2, POLE2, POLE3, RRM1, RRM2B, and RRM2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fludarabine phosphate%" OR LOWER(tradeNames_list)... | [{'UUID': 'DrugTargetsIndication121923_text_754189', 'drugName': 'Fludarabine Phosphate', 'tradeNames_list': "['Fludara', 'Fludarabine phosphate', 'Oforta']", 'syns_list': '[\'2-f-ara-amp\', \'2-f-araa\', \'2-fluoro ara-a\', \'2-fluorovidarabineFludarabine\', "Fludarabine 5\'-monophosphateFludarabine monophosphateFluda... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.340 | Q6 | What genes does Lidocaine target when it's used to treat carpal tunnel syndrome? | Lidocaine has not been approved by the FDA as a treatment for carpal tunnel syndrome, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lidocaine%" OR LOWER(tradeNames_list) LIKE "%lido... | [{'UUID': 'DrugTargetsIndication121923_text_638325', 'drugName': 'Lidocaine', 'tradeNames_list': "['Alphacaine', 'Anestacon', 'Dentipatch', 'Lidocaine', 'LidodermLignocaine Hcl', 'Lignostab', 'Lmx 4', 'Oraqix', 'Vagisil', 'XylocaineXylodase', 'Xylotox', 'Ztlido']", 'syns_list': "['ALGRX 3268', 'ALGRX-3268', 'Anestacon'... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.48 | Q6 | What genes does Lapatinib Ditosylate target when it's used to treat breast cancer? | When used to treat breast cancer, the drug Lapatinib Ditosylate targets the genes EGFR and ERBB2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lapatinib ditosylate%" OR LOWER(tradeNames_list) ... | [{'UUID': 'DrugTargetsIndication121923_text_217409', 'drugName': 'Lapatinib Ditosylate', 'tradeNames_list': "['Tykerb']", 'syns_list': "['GW-572016F', 'GW572016F', 'LapatinibLapatinib ditoluenesulfonate monohydrate', 'Lapatinib ditosylateLapatinib ditosylate anhydrous', 'Lapatinib ditosylate monohydrateLapatinib tosila... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1481 | Q6 | What genes does Liraglutide target when it's used to treat diabetes mellitus? | When used to treat diabetes mellitus, the drug Liraglutide targets the gene GLP1R. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%liraglutide%" OR LOWER(tradeNames_list) LIKE "%li... | [{'UUID': 'DrugTargetsIndication121923_text_1044954', 'drugName': 'Liraglutide', 'tradeNames_list': "['Saxenda', 'Victoza']", 'syns_list': "['Liraglutide', 'Liraglutide (rdna origin)', 'Liraglutide recombinantNN-2211', 'NN-9924', 'NN2211', 'NN9924', 'NNC 90-1170', 'NNC-90-1170']", 'target': 'ENSG00000112164', 'approved... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.109 | Q6 | What genes does Lenvatinib target when it's used to treat cancer? | When used to treat cancer, the drug Lenvatinib targets the genes KDR, FLT1, and FLT4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lenvatinib%" OR LOWER(tradeNames_list) LIKE "%len... | [{'UUID': 'DrugTargetsIndication121923_text_691880', 'drugName': 'Lenvatinib', 'tradeNames_list': "['Kisplyx', 'Lenvima']", 'syns_list': "['E-7080', 'ER-203492-00', 'Lenvatinib']", 'target': 'ENSG00000037280', 'approvedSymbol': 'FLT4', 'approvedName': 'fms related receptor tyrosine kinase 4', 'mesh_heading': 'Neoplasms... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.353 | Q6 | What genes does Lisinopril target when it's used to treat hypertension? | When used to treat hypertension, the drug Lisinopril targets the gene ACE. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lisinopril%" OR LOWER(tradeNames_list) LIKE "%lis... | [{'UUID': 'DrugTargetsIndication121923_text_1091710', 'drugName': 'Lisinopril', 'tradeNames_list': "['Acemin', 'Carace', 'Lisinopril', 'Lisopress', 'Prinivil', 'Qbrelis', 'Zestril']", 'syns_list': "['Lisinopril', 'Lisinopril dihydrate', 'Lisinopril hydrate', 'MK-521Ranolip']", 'target': 'ENSG00000159640', 'approvedSymb... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.241 | Q6 | What genes does Phentolamine Mesylate target when it's used to treat adrenal gland pheochromocytoma? | When used to treat adrenal gland pheochromocytoma, the drug Phentolamine Mesylate targets the genes ADRA1A, ADRA1D, ADRA1B, ADRA2A, ADRA2C, and ADRA2B. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%phentolamine mesylate%" OR LOWER(tradeNames_list)... | [{'UUID': 'DrugTargetsIndication121923_text_418223', 'drugName': 'Phentolamine Mesylate', 'tradeNames_list': "['Oraverse', 'Phentolamine mesylate', 'Regitine', 'Rogitine']", 'syns_list': "['Mesylate phentolamine', 'NV-101', 'Phentolamine mesilatePhentolamine mesylate', 'Phentolamine methanesulfonate']", 'target': 'ENSG... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.216 | Q6 | What genes does Belinostat target when it's used to treat follicular lymphoma? | Belinostat has not been approved by the FDA as a treatment for follicular lymphoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are HDAC1, HDAC3, HDAC6, HDAC2, HDAC5, HDAC7, HDAC8, HDAC11, HDAC4, HDAC9, and HDAC10. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%belinostat%" OR LOWER(tradeNames_list) LIKE "%bel... | [{'UUID': 'DrugTargetsIndication121923_text_1079973', 'drugName': 'Belinostat', 'tradeNames_list': "['Beleodaq']", 'syns_list': "['Belinostat', 'NSC-726630', 'NSC726630', 'PX-105684', 'PXD-101', 'PXD101']", 'target': 'ENSG00000094631', 'approvedSymbol': 'HDAC6', 'approvedName': 'histone deacetylase 6', 'mesh_heading': ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1827 | Q6 | What genes does Ivosidenib target when it's used to treat neoplasm? | When used to treat neoplasm, the drug Ivosidenib targets the gene IDH1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ivosidenib%" OR LOWER(tradeNames_list) LIKE "%ivo... | [{'UUID': 'DrugTargetsIndication121923_text_924579', 'drugName': 'Ivosidenib', 'tradeNames_list': "['Tibsovo']", 'syns_list': "['AG-120', 'Ivosidenib']", 'target': 'ENSG00000138413', 'approvedSymbol': 'IDH1', 'approvedName': 'isocitrate dehydrogenase (NADP(+)) 1', 'mesh_heading': 'Neoplasms', 'efo_term': 'neoplasm', 'y... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1138 | Q6 | What genes does Belinostat target when it's used to treat unspecified peripheral T-cell lymphoma? | When used to treat unspecified peripheral T-cell lymphoma, the drug Belinostat targets the genes HDAC1, HDAC3, HDAC6, HDAC2, HDAC5, HDAC7, HDAC8, HDAC11, HDAC4, HDAC9, and HDAC10. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%belinostat%" OR LOWER(tradeNames_list) LIKE "%bel... | [{'UUID': 'DrugTargetsIndication121923_text_1079993', 'drugName': 'Belinostat', 'tradeNames_list': "['Beleodaq']", 'syns_list': "['Belinostat', 'NSC-726630', 'NSC726630', 'PX-105684', 'PXD-101', 'PXD101']", 'target': 'ENSG00000094631', 'approvedSymbol': 'HDAC6', 'approvedName': 'histone deacetylase 6', 'mesh_heading': ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.800 | Q6 | What genes does Everolimus target when it's used to treat subependymal giant cell astrocytoma? | When used to treat subependymal giant cell astrocytoma, the drug Everolimus targets the gene FKBP1A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%everolimus%" OR LOWER(tradeNames_list) LIKE "%eve... | [{'UUID': 'DrugTargetsIndication121923_text_1085645', 'drugName': 'Everolimus', 'tradeNames_list': "['Afinitor', 'Afinitor disperz', 'Certican', 'Votubia', 'Zortress']", 'syns_list': "['40-o-(2-hydroxyethyl)-rapamycin', 'Everolimus', 'RAD 666', 'RAD-001RAD-666', 'RAD001', 'SDZ-RAD', 'Sdz rad']", 'target': 'ENSG00000088... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1123 | Q6 | What genes does Binimetinib target when it's used to treat melanoma? | When used to treat melanoma, the drug Binimetinib targets the genes MAP2K2 and MAP2K1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%binimetinib%" OR LOWER(tradeNames_list) LIKE "%bi... | [{'UUID': 'DrugTargetsIndication121923_text_926681', 'drugName': 'Binimetinib', 'tradeNames_list': "['Mektovi']", 'syns_list': "['ARRY 438162', 'ARRY-162', 'ARRY-438162', 'Binimetinib', 'MEK-162', 'MEK162Mek-162', 'NVP-MEK162']", 'target': 'ENSG00000126934', 'approvedSymbol': 'MAP2K2', 'approvedName': 'mitogen-activate... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1583 | Q6 | What genes does Bupivacaine Hydrochloride target when it's used to treat pain? | When used to treat pain, the drug Bupivacaine Hydrochloride targets the gene SCN4A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%bupivacaine hydrochloride%" OR LOWER(tradeNames_l... | [{'UUID': 'DrugTargetsIndication121923_text_664030', 'drugName': 'Bupivacaine Hydrochloride', 'tradeNames_list': "['Bupivac hcl', 'Bupivacaine hydrochloride', 'Bupivacaine hydrochloride kitBupivacaine hydrochloride preservative free', 'Marcain', 'MarcaineMarcaine hydrochloride', 'Marcaine hydrochloride preservative fre... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
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