uuid stringlengths 4 8 | template_uuid stringclasses 40
values | question stringlengths 13 193 | answer stringlengths 29 2.2k | benchmark_query stringlengths 133 622 | execution_results stringlengths 2 1.14M | query_type stringclasses 2
values | sql_category stringclasses 26
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Q6.1672 | Q6 | What genes does Tucatinib target when it's used to treat breast carcinoma? | When used to treat breast carcinoma, the drug Tucatinib targets the gene ERBB2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%tucatinib%" OR LOWER(tradeNames_list) LIKE "%tuca... | [{'UUID': 'DrugTargetsIndication121923_text_924481', 'drugName': 'Tucatinib', 'tradeNames_list': "['Tukysa']", 'syns_list': "['ARRY-380', 'Irbinitinib', 'ONT-380', 'Ont-380', 'Tucatinib']", 'target': 'ENSG00000141736', 'approvedSymbol': 'ERBB2', 'approvedName': 'erb-b2 receptor tyrosine kinase 2', 'mesh_heading': 'Brea... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.529 | Q6 | What genes does Oxymetazoline Hydrochloride target when it's used to treat allergic rhinitis? | When used to treat allergic rhinitis, the drug Oxymetazoline Hydrochloride targets the genes ADRA1A, ADRA1D, ADRA1B, ADRA2A, ADRA2C, and ADRA2B. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%oxymetazoline hydrochloride%" OR LOWER(tradeNames... | [{'UUID': 'DrugTargetsIndication121923_text_417211', 'drugName': 'Oxymetazoline Hydrochloride', 'tradeNames_list': "['Afrazine', 'Ocuclear', 'Rhofade', 'Upneeq', 'Visine', 'Visine l.r.']", 'syns_list': "['Agn-199201', 'NSC-757254', 'Oximetazoline hydrochlorideOxymetazoline hcl', 'Oxymetazoline hydrochloride', 'SCH 9384... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.235 | Q6 | What genes does Panobinostat target when it's used to treat graft versus host disease? | Panobinostat has not been approved by the FDA as a treatment for graft versus host disease, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are HDAC1, HDAC3, HDAC6, HDAC2, HDAC5, HDAC7, HDAC8, HDAC11, HDAC4, HDAC9, and HDAC10. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%panobinostat%" OR LOWER(tradeNames_list) LIKE "%p... | [{'UUID': 'DrugTargetsIndication121923_text_1080932', 'drugName': 'Panobinostat', 'tradeNames_list': "['Farydak']", 'syns_list': "['LBH-589', 'LBH589', 'Panobinostat', 'Panobinostat hydrate']", 'target': 'ENSG00000116478', 'approvedSymbol': 'HDAC1', 'approvedName': 'histone deacetylase 1', 'mesh_heading': 'Graft vs Hos... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.651 | Q6 | What genes does Methotrexate target when it's used to treat systemic scleroderma? | Methotrexate has not been approved by the FDA as a treatment for systemic scleroderma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is DHFR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%methotrexate%" OR LOWER(tradeNames_list) LIKE "%m... | [{'UUID': 'DrugTargetsIndication121923_text_1057445', 'drugName': 'Methotrexate', 'tradeNames_list': "['Amethopterin', 'Ebetrex', 'Emtexate high-pot', 'Emtexate pf', 'FolexMaxtrex', 'Methotrexate', 'Metoject', 'Mexate', 'Otrexup', 'Otrexup pfsRasuvo', 'Reditrex', 'Rheumatrex', 'Trexall', 'Zlatal']", 'syns_list': "['(r)... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1509 | Q6 | What genes does Cyclosporine target when it's used to treat lung disease? | Cyclosporine has not been approved by the FDA as a treatment for lung disease, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is PPIA. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%cyclosporine%" OR LOWER(tradeNames_list) LIKE "%c... | [{'UUID': 'DrugTargetsIndication121923_text_1101202', 'drugName': 'Cyclosporine', 'tradeNames_list': "['Capimune', 'Capsorin', 'Cequa', 'Cyclosporine', 'Deximune', 'GengrafIkervis', 'Neoral', 'Optimmune', 'Restasis', 'Restasis multidoseSandimmun', 'Sandimmune', 'Sangcya', 'Vanquoral', 'Verkazia']", 'syns_list': "['27-4... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.539 | Q6 | What genes does Celecoxib target when it's used to treat ankylosing spondylitis? | When used to treat ankylosing spondylitis, the drug Celecoxib targets the gene PTGS2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%celecoxib%" OR LOWER(tradeNames_list) LIKE "%cele... | [{'UUID': 'DrugTargetsIndication121923_text_833499', 'drugName': 'Celecoxib', 'tradeNames_list': "['Celebra', 'Celebrex', 'Celecoxib', 'Elyxyb', 'Onsenal']", 'syns_list': "['Celecoxib', 'DFN-15', 'DFN15', 'NSC-719627', 'NSC-758624', 'SC-58635']", 'target': 'ENSG00000073756', 'approvedSymbol': 'PTGS2', 'approvedName': '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1753 | Q6 | What genes does Epinephrine target when it's used to treat musculoskeletal system disease? | Epinephrine has not been approved by the FDA as a treatment for musculoskeletal system disease, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are ADRA1A, ADRB2, ADRB1, ADRB3, ADRA1D, ADRA1B, ADRA2A, ADRA2C, and ADRA2B. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%epinephrine%" OR LOWER(tradeNames_list) LIKE "%ep... | [{'UUID': 'DrugTargetsIndication121923_text_361070', 'drugName': 'Epinephrine', 'tradeNames_list': "['Adren co', 'Adrenaclick', 'Adrenalin', 'Ana-Kit', 'Ana-guard', 'AnapenAnaphylactic shock drug kit', 'Asma-vydrin', 'Asthmahaler', 'Auvi-qBronkaid mist', 'Brovon', 'Emerade', 'Epi e z pen jr', 'EpinephrineEpinephrine (c... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.610 | Q6 | What genes does Regorafenib target when it's used to treat adenoid cystic carcinoma? | Regorafenib has not been approved by the FDA as a treatment for adenoid cystic carcinoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are KDR, FGFR1, FGFR2, ABL1, BRAF, TEK, FLT1, KIT, FLT4, PDGFRB, PDGFRA, RAF1, EPHA2, FRK, NTRK1, RET, DDR2, and MAPK11. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%regorafenib%" OR LOWER(tradeNames_list) LIKE "%re... | [{'UUID': 'DrugTargetsIndication121923_text_664216', 'drugName': 'Regorafenib', 'tradeNames_list': "['Stivarga']", 'syns_list': "['BAY 73-4506', 'BAY 73-4506 monohydrate', 'BAY-73-4506', 'BAY-734506Regorafenib', 'Regorafenib anhydrous', 'Regorafenib hydrateRegorafenib monohydrate']", 'target': 'ENSG00000077782', 'appro... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1780 | Q6 | What genes does Alectinib target when it's used to treat melanoma? | Alectinib has not been approved by the FDA as a treatment for melanoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are RET, ALK, and EML4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%alectinib%" OR LOWER(tradeNames_list) LIKE "%alec... | [{'UUID': 'DrugTargetsIndication121923_text_945677', 'drugName': 'Alectinib', 'tradeNames_list': "['Alecensa']", 'syns_list': "['AF-802', 'AF802', 'Alectinib', 'CH-5424802', 'CH5424802', 'RO-5424802RO5424802']", 'target': 'ENSG00000171094', 'approvedSymbol': 'ALK', 'approvedName': 'ALK receptor tyrosine kinase', 'mesh_... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1083 | Q6 | What genes does Tadalafil target when it's used to treat Impotence? | When used to treat Impotence, the drug Tadalafil targets the gene PDE5A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%tadalafil%" OR LOWER(tradeNames_list) LIKE "%tada... | [{'UUID': 'DrugTargetsIndication121923_text_1094099', 'drugName': 'Tadalafil', 'tradeNames_list': "['Adcirca', 'Cialis', 'Tadliq']", 'syns_list': "['IC-351', 'IC351', 'LY-450190', 'LY450190', 'NSC-750236', 'NSC-759172Tadalafil', 'Tadalafil mylan', 'Trans-tadalafil']", 'target': 'ENSG00000138735', 'approvedSymbol': 'PDE... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1407 | Q6 | What genes does Lenvatinib target when it's used to treat neoplasm? | When used to treat neoplasm, the drug Lenvatinib targets the genes KDR, FLT1, and FLT4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lenvatinib%" OR LOWER(tradeNames_list) LIKE "%len... | [{'UUID': 'DrugTargetsIndication121923_text_690537', 'drugName': 'Lenvatinib', 'tradeNames_list': "['Kisplyx', 'Lenvima']", 'syns_list': "['E-7080', 'ER-203492-00', 'Lenvatinib']", 'target': 'ENSG00000128052', 'approvedSymbol': 'KDR', 'approvedName': 'kinase insert domain receptor', 'mesh_heading': 'Neoplasms', 'efo_te... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.62 | Q6 | What genes does Ertugliflozin target when it's used to treat type 2 diabetes mellitus? | When used to treat type 2 diabetes mellitus, the drug Ertugliflozin targets the gene SLC5A2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ertugliflozin%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_1096239', 'drugName': 'Ertugliflozin', 'tradeNames_list': "['Steglatro']", 'syns_list': "['Ertugliflozin', 'Ertugliflozin l-pyroglutamic acidErtugliflozin pidolate', 'MK-8835', 'PF-04971729', 'PF-04971729-00PF04971729', 'Pf-04971729']", 'target': 'ENSG00000140675', 'approvedS... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1643 | Q6 | What genes does Spironolactone target when it's used to treat hypertension? | When used to treat hypertension, the drug Spironolactone targets the gene NR3C2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%spironolactone%" OR LOWER(tradeNames_list) LIKE "... | [{'UUID': 'DrugTargetsIndication121923_text_1094464', 'drugName': 'Spironolactone', 'tradeNames_list': "['Abbolactone', 'Aldactone', 'Carospir', 'Diatensec', 'Gx spironolLaractone', 'Spiretic', 'Spiroctan 100', 'Spiroctan 25', 'Spiroctan 50Spironolactone', 'Spirospare 100', 'Spirospare 25']", 'syns_list': "['NSC-150399... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.95 | Q6 | What genes does Tretinoin target when it's used to treat amyotrophic lateral sclerosis? | Tretinoin has not been approved by the FDA as a treatment for amyotrophic lateral sclerosis, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are RARG, RARB, and RARA. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%tretinoin%" OR LOWER(tradeNames_list) LIKE "%tret... | [{'UUID': 'DrugTargetsIndication121923_text_1053687', 'drugName': 'Tretinoin', 'tradeNames_list': "['Acticin', 'Altreno', 'Atralin', 'Avita', 'Renova', 'Retin-a', 'Retin-a microRetin-a-micro', 'Tretin-X', 'Tretinoin', 'Vesanoid']", 'syns_list': "['Aberel', 'All-trans retinoic acid', 'All-trans-retinoic acid', 'EudynaKe... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.673 | Q6 | What genes does Indacaterol Maleate target when it's used to treat chronic obstructive pulmonary disease? | When used to treat chronic obstructive pulmonary disease, the drug Indacaterol Maleate targets the gene ADRB2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%indacaterol maleate%" OR LOWER(tradeNames_list) L... | [{'UUID': 'DrugTargetsIndication121923_text_937187', 'drugName': 'Indacaterol Maleate', 'tradeNames_list': "['Arcapta neohaler', 'Onbrez breezhaler']", 'syns_list': "['Indacaterol (as maleate)', 'Indacaterol maleate', 'Indacterol maleateQAB-149-AFA', 'QAB149-AFA']", 'target': 'ENSG00000169252', 'approvedSymbol': 'ADRB2... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.284 | Q6 | What genes does Dabrafenib Mesylate target when it's used to treat thyroid cancer? | When used to treat thyroid cancer, the drug Dabrafenib Mesylate targets the gene BRAF. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dabrafenib mesylate%" OR LOWER(tradeNames_list) L... | [{'UUID': 'DrugTargetsIndication121923_text_752715', 'drugName': 'Dabrafenib Mesylate', 'tradeNames_list': "['Tafinlar']", 'syns_list': "['Dabrafenib mesilate', 'Dabrafenib mesylateGSK-2118436 METHANESULFONATE SALT', 'GSK-2118436BGSK-2118436B MESYLATE', 'GSK-2118436B METHANESULFONATE SALTGSK2118436B', 'GSK2118436B, MET... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1796 | Q6 | What genes does Lidocaine target when it's used to treat sunburn? | When used to treat sunburn, the drug Lidocaine targets the genes SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lidocaine%" OR LOWER(tradeNames_list) LIKE "%lido... | [{'UUID': 'DrugTargetsIndication121923_text_638359', 'drugName': 'Lidocaine', 'tradeNames_list': "['Alphacaine', 'Anestacon', 'Dentipatch', 'Lidocaine', 'LidodermLignocaine Hcl', 'Lignostab', 'Lmx 4', 'Oraqix', 'Vagisil', 'XylocaineXylodase', 'Xylotox', 'Ztlido']", 'syns_list': "['ALGRX 3268', 'ALGRX-3268', 'Anestacon'... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.364 | Q6 | What genes does Lidocaine target when it's used to treat osteoarthritis? | When used to treat osteoarthritis, the drug Lidocaine targets the genes SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lidocaine%" OR LOWER(tradeNames_list) LIKE "%lido... | [{'UUID': 'DrugTargetsIndication121923_text_641591', 'drugName': 'Lidocaine', 'tradeNames_list': "['Alphacaine', 'Anestacon', 'Dentipatch', 'Lidocaine', 'LidodermLignocaine Hcl', 'Lignostab', 'Lmx 4', 'Oraqix', 'Vagisil', 'XylocaineXylodase', 'Xylotox', 'Ztlido']", 'syns_list': "['ALGRX 3268', 'ALGRX-3268', 'Anestacon'... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1468 | Q6 | What genes does Apixaban target when it's used to treat Venous thrombosis? | When used to treat Venous thrombosis, the drug Apixaban targets the gene F10. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%apixaban%" OR LOWER(tradeNames_list) LIKE "%apixa... | [{'UUID': 'DrugTargetsIndication121923_text_710422', 'drugName': 'Apixaban', 'tradeNames_list': "['Eliquis']", 'syns_list': "['Apixaban', 'BMS-562247', 'BMS-562247-01']", 'target': 'ENSG00000126218', 'approvedSymbol': 'F10', 'approvedName': 'coagulation factor X', 'mesh_heading': 'Venous Thrombosis', 'efo_term': 'deep ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1169 | Q6 | What genes does Plerixafor target when it's used to treat acute myeloid leukemia? | Plerixafor has not been approved by the FDA as a treatment for acute myeloid leukemia, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is CXCR4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%plerixafor%" OR LOWER(tradeNames_list) LIKE "%ple... | [{'UUID': 'DrugTargetsIndication121923_text_1103181', 'drugName': 'Plerixafor', 'tradeNames_list': "['Mozobil']", 'syns_list': "['AMD 3100', 'AMD3100', 'JM 3100', 'Plerixafor', 'Plerixafor hydrochloridePlerixafor octahydrochloride', 'SID 791']", 'target': 'ENSG00000121966', 'approvedSymbol': 'CXCR4', 'approvedName': 'C... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.854 | Q6 | What genes does Ibuprofen target when it's used to treat Arthralgia? | When used to treat Arthralgia, the drug Ibuprofen targets the genes PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ibuprofen%" OR LOWER(tradeNames_list) LIKE "%ibup... | [{'UUID': 'DrugTargetsIndication121923_text_840157', 'drugName': 'Ibuprofen', 'tradeNames_list': '[\'Aches-n-pain\', \'Advil\', \'Advil liqui-gels\', \'Advil migraine liqui-gelsAnadin joint pain\', \'Anadin liquifast\', \'Anadin period pain reliefAnadin ultra\', \'Apsifen\', \'Apsifen-f\', \'Arthrofen 200\', \'Arthrofe... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1379 | Q6 | What genes does Zolpidem Tartrate target when it's used to treat Sleep Disorder? | Zolpidem Tartrate has not been approved by the FDA as a treatment for Sleep Disorder, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are GABRA1, GABRG2, and GABRB1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%zolpidem tartrate%" OR LOWER(tradeNames_list) LIK... | [{'UUID': 'DrugTargetsIndication121923_text_958345', 'drugName': 'Zolpidem Tartrate', 'tradeNames_list': "['Ambien', 'Ambien cr', 'Edluar', 'Intermezzo', 'Stilnoct', 'Tovalt odtZolpidem tartrate', 'Zolpimist']", 'syns_list': "['Ivadal', 'Myslee', 'Niotal', 'SL 80.0750-23N', 'SL-80.0750', 'SL-80.0750-23NStilnox', 'Toval... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.113 | Q6 | What genes does Loxapine target when it's used to treat Agitation? | When used to treat Agitation, the drug Loxapine targets the genes HTR2C, DRD2, DRD3, DRD4, and HTR2A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%loxapine%" OR LOWER(tradeNames_list) LIKE "%loxap... | [{'UUID': 'DrugTargetsIndication121923_text_149075', 'drugName': 'Loxapine', 'tradeNames_list': "['Adasuve', 'Loxitane intramuscular [as hydrochloride]Loxitane-c oral suspension [as hydrochloride]']", 'syns_list': "['CL 62,362', 'CL-62362', 'Loxapac', 'Loxapine', 'Loxitane', 'SUM 3170SUM-3170']", 'target': 'ENSG0000014... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.43 | Q6 | What genes does Clobazam target when it's used to treat Lennox-Gastaut syndrome? | When used to treat Lennox-Gastaut syndrome, the drug Clobazam targets the genes GABRA1, GABRB2, GABRG2, GABRB3, GABRA4, GABRG3, GABRQ, GABRA3, GABRP, GABRD, GABRG1, GABRB1, GABRE, GABRA2, GABRA5, and GABRA6. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%clobazam%" OR LOWER(tradeNames_list) LIKE "%cloba... | [{'UUID': 'DrugTargetsIndication121923_text_947360', 'drugName': 'Clobazam', 'tradeNames_list': "['Frisium', 'Onfi', 'Perizam', 'Sympazan', 'Tapclob', 'Urbanyl']", 'syns_list': "['Clobazam', 'Colbazam', 'H 4723', 'H-4723', 'HR 376', 'HR-376', 'LM 2717LM-2717', 'Mystan', 'NSC-336279', 'Urbadan']", 'target': 'ENSG0000002... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.128 | Q6 | What genes does Dexamethasone target when it's used to treat type III hypersensitivity reaction disease? | When used to treat type III hypersensitivity reaction disease, the drug Dexamethasone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dexamethasone%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_227796', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.207 | Q6 | What genes does Lamotrigine target when it's used to treat partial epilepsy? | When used to treat partial epilepsy, the drug Lamotrigine targets the genes SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lamotrigine%" OR LOWER(tradeNames_list) LIKE "%la... | [{'UUID': 'DrugTargetsIndication121923_text_653153', 'drugName': 'Lamotrigine', 'tradeNames_list': "['Lamictal', 'Lamictal cd', 'Lamictal odt', 'Lamictal xr', 'Lamotrigine']", 'syns_list': "['BW 430C', 'BW-430C', 'Lamotrigine', 'NSC-759171']", 'target': 'ENSG00000144285', 'approvedSymbol': 'SCN1A', 'approvedName': 'sod... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.53 | Q6 | What genes does Bosentan target when it's used to treat hypertension? | When used to treat hypertension, the drug Bosentan targets the genes EDNRA and EDNRB. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%bosentan%" OR LOWER(tradeNames_list) LIKE "%bosen... | [{'UUID': 'DrugTargetsIndication121923_text_1084233', 'drugName': 'Bosentan', 'tradeNames_list': "['Tracleer']", 'syns_list': "['Anhydrous bosentan', 'Bosentan', 'Bosentan anhydrous', 'Bosentan hydrateBosentan monohydrate', 'RO 47-0203/029', 'RO-47-0203-029', 'RO-470203029']", 'target': 'ENSG00000151617', 'approvedSymb... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.551 | Q6 | What genes does Dexamethasone target when it's used to treat ophthalmic herpes zoster? | When used to treat ophthalmic herpes zoster, the drug Dexamethasone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dexamethasone%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_227775', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.71 | Q6 | What genes does Prednisone target when it's used to treat Iridocyclitis? | When used to treat Iridocyclitis, the drug Prednisone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%prednisone%" OR LOWER(tradeNames_list) LIKE "%pre... | [{'UUID': 'DrugTargetsIndication121923_text_218662', 'drugName': 'Prednisone', 'tradeNames_list': "['Cortan', 'Cortancyl', 'Decortisyl', 'Delta-dome', 'Deltasone', 'FernisoneLiquid pred', 'Lodotra', 'Meticorten', 'Orasone', 'Paracort', 'Prednicen-mPrednisone', 'Prednisone intensol', 'Rayos', 'Servisone', 'Sterapred']",... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1816 | Q6 | What genes does Palbociclib target when it's used to treat neoplasm? | When used to treat neoplasm, the drug Palbociclib targets the genes CDK4, CDK6, and CCND1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%palbociclib%" OR LOWER(tradeNames_list) LIKE "%pa... | [{'UUID': 'DrugTargetsIndication121923_text_852060', 'drugName': 'Palbociclib', 'tradeNames_list': "['Ibrance']", 'syns_list': "['PD-0332991', 'Palbociclib']", 'target': 'ENSG00000135446', 'approvedSymbol': 'CDK4', 'approvedName': 'cyclin dependent kinase 4', 'mesh_heading': 'Neoplasms', 'efo_term': 'cancer', 'yearOfFi... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1745 | Q6 | What genes does Duloxetine Hydrochloride target when it's used to treat major depressive disorder? | When used to treat major depressive disorder, the drug Duloxetine Hydrochloride targets the genes SLC6A4 and SLC6A2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%duloxetine hydrochloride%" OR LOWER(tradeNames_li... | [{'UUID': 'DrugTargetsIndication121923_text_206080', 'drugName': 'Duloxetine Hydrochloride', 'tradeNames_list': "['Ariclaim', 'Cymbalta', 'Drizalma sprinkle', 'DuciltiaDuloxetine hydrochloride', 'Yentreve']", 'syns_list': "['Ariclaim', 'Duloxetine (as hydrochloride)', 'Duloxetine hclDuloxetine hydrochloride', 'Duloxeti... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.186 | Q6 | What genes does Cangrelor Tetrasodium target when it's used to treat Recurrent thrombophlebitis? | When used to treat Recurrent thrombophlebitis, the drug Cangrelor Tetrasodium targets the gene P2RY12. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%cangrelor tetrasodium%" OR LOWER(tradeNames_list)... | [{'UUID': 'DrugTargetsIndication121923_text_921002', 'drugName': 'Cangrelor Tetrasodium', 'tradeNames_list': "['Kengreal']", 'syns_list': "['AR-C69931MX', 'Cangrelor', 'Cangrelor tetrasodiumCangrelor tetrasodium salt', 'Kengrexal']", 'target': 'ENSG00000169313', 'approvedSymbol': 'P2RY12', 'approvedName': 'purinergic r... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.140 | Q6 | What genes does Fluorouracil target when it's used to treat cholangiocarcinoma? | Fluorouracil has not been approved by the FDA as a treatment for cholangiocarcinoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is TYMS. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fluorouracil%" OR LOWER(tradeNames_list) LIKE "%f... | [{'UUID': 'DrugTargetsIndication121923_text_919424', 'drugName': 'Fluorouracil', 'tradeNames_list': "['5.f.u.', 'Accusite', 'Actikerall', 'Adrucil', 'Carac', 'Efudex', 'EfudixFluoro-uracil roche', 'Fluoroplex', 'Fluorouracil', 'Tolak']", 'syns_list': "['5 FU', '5-FU', '5-Fluorouracil', '5-fluoruracil', 'FluorouracilFlu... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.907 | Q6 | What genes does Methotrexate target when it's used to treat malignant pleural mesothelioma? | Methotrexate has not been approved by the FDA as a treatment for malignant pleural mesothelioma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is DHFR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%methotrexate%" OR LOWER(tradeNames_list) LIKE "%m... | [{'UUID': 'DrugTargetsIndication121923_text_1057462', 'drugName': 'Methotrexate', 'tradeNames_list': "['Amethopterin', 'Ebetrex', 'Emtexate high-pot', 'Emtexate pf', 'FolexMaxtrex', 'Methotrexate', 'Metoject', 'Mexate', 'Otrexup', 'Otrexup pfsRasuvo', 'Reditrex', 'Rheumatrex', 'Trexall', 'Zlatal']", 'syns_list': "['(r)... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.803 | Q6 | What genes does Azilsartan Kamedoxomil target when it's used to treat stroke? | When used to treat stroke, the drug Azilsartan Kamedoxomil targets the gene AGTR1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%azilsartan kamedoxomil%" OR LOWER(tradeNames_list... | [{'UUID': 'DrugTargetsIndication121923_text_1072676', 'drugName': 'Azilsartan Kamedoxomil', 'tradeNames_list': "['Edarbi']", 'syns_list': "['Azilsartan kamedoxomil', 'Azilsartan medoxomil potassium', 'TAK-491']", 'target': 'ENSG00000144891', 'approvedSymbol': 'AGTR1', 'approvedName': 'angiotensin II receptor type 1', '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.135 | Q6 | What genes does Triptorelin Pamoate target when it's used to treat precocious puberty? | When used to treat precocious puberty, the drug Triptorelin Pamoate targets the gene GNRHR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%triptorelin pamoate%" OR LOWER(tradeNames_list) L... | [{'UUID': 'DrugTargetsIndication121923_text_1097288', 'drugName': 'Triptorelin Pamoate', 'tradeNames_list': "['Trelstar', 'Triptodur kit']", 'syns_list': "['Salvacyl', 'Triptorelin (as embonate)', 'Triptorelin embonateTriptorelin pamoate']", 'target': 'ENSG00000109163', 'approvedSymbol': 'GNRHR', 'approvedName': 'gonad... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.83 | Q6 | What genes does Febuxostat target when it's used to treat hyperuricemia? | When used to treat hyperuricemia, the drug Febuxostat targets the gene XDH. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%febuxostat%" OR LOWER(tradeNames_list) LIKE "%feb... | [{'UUID': 'DrugTargetsIndication121923_text_1095561', 'drugName': 'Febuxostat', 'tradeNames_list': "['Adenuric', 'Uloric']", 'syns_list': "['Febuxostat', 'NSC-758874', 'TMX-67']", 'target': 'ENSG00000158125', 'approvedSymbol': 'XDH', 'approvedName': 'xanthine dehydrogenase', 'mesh_heading': 'Hyperuricemia', 'efo_term':... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1541 | Q6 | What genes does Famotidine target when it's used to treat Peptic ulcer? | When used to treat Peptic ulcer, the drug Famotidine targets the gene HRH2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%famotidine%" OR LOWER(tradeNames_list) LIKE "%fam... | [{'UUID': 'DrugTargetsIndication121923_text_1100332', 'drugName': 'Famotidine', 'tradeNames_list': "['Famotidine', 'Famotidine preservative freeFamotidine preservative free (pharmacy bulk)', 'Fluxid', 'PepcidPepcid ac', 'Pepcid preservative free', 'Pepcid rpd']", 'syns_list': "['Amfamox', 'Fadul', 'Famodil', 'Famosan',... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.547 | Q6 | What genes does Pregabalin target when it's used to treat fibromyalgia? | When used to treat fibromyalgia, the drug Pregabalin targets the genes CACNA1B, CACNA1C, CACNA1S, CACNA1D, CACNA1F, CACNA2D2, CACNA2D1, CACNA1H, CACNA1G, CACNA1I, CACNA1A, CACNA2D3, CACNA2D4, CACNA1E, CACNB4, CACNB2, CACNB1, CACNB3, CACNG7, CACNG5, CACNG2, CACNG4, CACNG8, CACNG3, CACNG6, and CACNG1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%pregabalin%" OR LOWER(tradeNames_list) LIKE "%pre... | [{'UUID': 'DrugTargetsIndication121923_text_859587', 'drugName': 'Pregabalin', 'tradeNames_list': "['Alzain', 'Axalid', 'Lecaent', 'Lyrica', 'Lyrica cr', 'Pregabalin', 'Rewisca']", 'syns_list': "['CI-1008', 'NSC-759256', 'PD-144723', 'Pregabalin', 'Pregabalin mylanPregabalin sandoz', 'Pregabalin sandoz gmbh', 'Pregabal... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1596 | Q6 | What genes does Rosuvastatin Calcium target when it's used to treat Hypercholesterolemia? | When used to treat Hypercholesterolemia, the drug Rosuvastatin Calcium targets the gene HMGCR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%rosuvastatin calcium%" OR LOWER(tradeNames_list) ... | [{'UUID': 'DrugTargetsIndication121923_text_1104167', 'drugName': 'Rosuvastatin Calcium', 'tradeNames_list': "['Crestor', 'Ezallor', 'Ezallor sprinkle', 'Rosuvastatin calcium']", 'syns_list': "['Fortius', 'NSC-747274', 'NSC-758930', 'Rostar', 'Rosuvastatin (as calcium)Rosuvastatin calcium', 'Rosuvastatin calcium saltRo... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.992 | Q6 | What genes does Docetaxel target when it's used to treat urethra cancer? | Docetaxel has not been approved by the FDA as a treatment for urethra cancer, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are TUBB4B, TUBB1, TUBA3C, TUBA4A, TUBB3, TUBA1A, TUBB4A, TUBB8, TUBB, TUBA1B, TUBA1C, TUBA3E, TUBB2A, TUBB2B, and TUBB6. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%docetaxel%" OR LOWER(tradeNames_list) LIKE "%doce... | [{'UUID': 'DrugTargetsIndication121923_text_96038', 'drugName': 'Docetaxel', 'tradeNames_list': "['Docefrez', 'Docetaxel', 'Taxceus', 'Taxotere']", 'syns_list': "['Bind 014', 'CKD-810', 'Docetaxel', 'Docetaxel (as trihydrate)Docetaxel anhydrous', 'Docetaxel hydrate', 'Docetaxel trihydrateNSC-628503', 'RP 56976', 'RP-56... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.168 | Q6 | What genes does Aclidinium Bromide target when it's used to treat asthma? | When used to treat asthma, the drug Aclidinium Bromide targets the gene CHRM3. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%aclidinium bromide%" OR LOWER(tradeNames_list) LI... | [{'UUID': 'DrugTargetsIndication121923_text_857461', 'drugName': 'Aclidinium Bromide', 'tradeNames_list': "['Eklira', 'Tudorza pressair']", 'syns_list': "['14115700', 'Aclidinium bromide', 'Genuair', 'LAS 34273LAS 34273 MICRONIZED', 'LAS W-330', 'LAS-34273', 'LAS-34273 MICRONIZEDLAS-W-330']", 'target': 'ENSG00000133019... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.251 | Q6 | What genes does Umeclidinium Bromide target when it's used to treat chronic bronchitis? | When used to treat chronic bronchitis, the drug Umeclidinium Bromide targets the gene CHRM3. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%umeclidinium bromide%" OR LOWER(tradeNames_list) ... | [{'UUID': 'DrugTargetsIndication121923_text_857417', 'drugName': 'Umeclidinium Bromide', 'tradeNames_list': "['Incruse ellipta']", 'syns_list': "['Anoro ellipta', 'GSK-573719A', 'GSK573719A', 'Umeclidinium bromUmeclidinium bromide']", 'target': 'ENSG00000133019', 'approvedSymbol': 'CHRM3', 'approvedName': 'cholinergic ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.452 | Q6 | What genes does Fluorouracil target when it's used to treat adenocarcinoma? | When used to treat adenocarcinoma, the drug Fluorouracil targets the gene TYMS. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fluorouracil%" OR LOWER(tradeNames_list) LIKE "%f... | [{'UUID': 'DrugTargetsIndication121923_text_919462', 'drugName': 'Fluorouracil', 'tradeNames_list': "['5.f.u.', 'Accusite', 'Actikerall', 'Adrucil', 'Carac', 'Efudex', 'EfudixFluoro-uracil roche', 'Fluoroplex', 'Fluorouracil', 'Tolak']", 'syns_list': "['5 FU', '5-FU', '5-Fluorouracil', '5-fluoruracil', 'FluorouracilFlu... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1148 | Q6 | What genes does Carbamazepine target when it's used to treat epilepsy? | When used to treat epilepsy, the drug Carbamazepine targets the genes SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%carbamazepine%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_633093', 'drugName': 'Oxcarbazepine', 'tradeNames_list': "['Oxcarbazepine', 'Oxtellar xr', 'Trileptal']", 'syns_list': "['GP-47680', 'KIN-493', 'NSC-758693', 'Oxcarbamazepine', 'OxcarbazepineSPN-804']", 'target': 'ENSG00000007314', 'approvedSymbol': 'SCN4A', 'approvedName': '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.865 | Q6 | What genes does Ixabepilone target when it's used to treat fallopian tube cancer? | Ixabepilone has not been approved by the FDA as a treatment for fallopian tube cancer, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are TUBB4B, TUBB1, TUBA3C, TUBA4A, TUBB3, TUBA1A, TUBB4A, TUBB8, TUBB, TUBA1B, TUBA1C, TUBA3E, TUBB2A, TUBB2B, and TUBB6. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ixabepilone%" OR LOWER(tradeNames_list) LIKE "%ix... | [{'UUID': 'DrugTargetsIndication121923_text_85061', 'drugName': 'Ixabepilone', 'tradeNames_list': "['Ixempra', 'Ixempra kit']", 'syns_list': "['Azaepothilone b', 'BMS 247550-01', 'BMS-247550', 'BMS-247550-01Ixabepilone', 'Ixempra', 'NSC-747973']", 'target': 'ENSG00000188229', 'approvedSymbol': 'TUBB4B', 'approvedName':... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1233 | Q6 | What genes does Linaclotide target when it's used to treat constipation disorder? | When used to treat constipation disorder, the drug Linaclotide targets the gene GUCY2C. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%linaclotide%" OR LOWER(tradeNames_list) LIKE "%li... | [{'UUID': 'DrugTargetsIndication121923_text_1092109', 'drugName': 'Linaclotide', 'tradeNames_list': "['Constella', 'Linzess']", 'syns_list': "['ASP-0456', 'ASP0456', 'Linaclotide', 'MD-1100']", 'target': 'ENSG00000070019', 'approvedSymbol': 'GUCY2C', 'approvedName': 'guanylate cyclase 2C', 'mesh_heading': 'Constipation... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.100 | Q6 | What genes does Prednisone target when it's used to treat oral lichen planus? | Prednisone has not been approved by the FDA as a treatment for oral lichen planus, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%prednisone%" OR LOWER(tradeNames_list) LIKE "%pre... | [{'UUID': 'DrugTargetsIndication121923_text_218567', 'drugName': 'Prednisone', 'tradeNames_list': "['Cortan', 'Cortancyl', 'Decortisyl', 'Delta-dome', 'Deltasone', 'FernisoneLiquid pred', 'Lodotra', 'Meticorten', 'Orasone', 'Paracort', 'Prednicen-mPrednisone', 'Prednisone intensol', 'Rayos', 'Servisone', 'Sterapred']",... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1974 | Q6 | What genes does Aspirin target when it's used to treat myocardial infarction? | When used to treat myocardial infarction, the drug Aspirin targets the genes PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%aspirin%" OR LOWER(tradeNames_list) LIKE "%aspiri... | [{'UUID': 'DrugTargetsIndication121923_text_834594', 'drugName': 'Aspirin', 'tradeNames_list': "['8-hour bayer', 'Acetosalic Acid', 'Acetylsalic acidAcetylsalicylic Acid', 'Alka rapid', 'Anadin all night', 'Angettes 75Aspirin', 'Aspro clr', 'Bayer extra strength aspirin for migraine painDanamep', 'Disprin cv', 'Disprin... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.744 | Q6 | What genes does Latanoprostene Bunod target when it's used to treat glaucoma? | When used to treat glaucoma, the drug Latanoprostene Bunod targets the gene PTGFR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%latanoprostene bunod%" OR LOWER(tradeNames_list) ... | [{'UUID': 'DrugTargetsIndication121923_text_1149109', 'drugName': 'Latanoprostene Bunod', 'tradeNames_list': "['Vesneo', 'Vyzulta']", 'syns_list': "['BOL-303259-X', 'Bol-303259-x', 'Latanoprostene bunod', 'NCX 116', 'NCX-116PF-3187207']", 'target': 'ENSG00000122420', 'approvedSymbol': 'PTGFR', 'approvedName': 'prostagl... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1252 | Q6 | What genes does Umbralisib Tosylate target when it's used to treat gastrointestinal stromal tumor? | Umbralisib Tosylate has not been approved by the FDA as a treatment for gastrointestinal stromal tumor, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are ABL1, PIK3CD, and CSNK1E. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%umbralisib tosylate%" OR LOWER(tradeNames_list) L... | [{'UUID': 'DrugTargetsIndication121923_text_744692', 'drugName': 'Umbralisib Tosylate', 'tradeNames_list': "['Ukoniq']", 'syns_list': "['RP-5307', 'TGR-1202', 'TGR-1202 (4-METHYLBENZENESULFONATE)', 'Tgr-1202Umbralisib tosylate']", 'target': 'ENSG00000097007', 'approvedSymbol': 'ABL1', 'approvedName': 'ABL proto-oncogen... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.105 | Q6 | What genes does Metoclopramide Hydrochloride target when it's used to treat Anorexia? | When used to treat Anorexia, the drug Metoclopramide Hydrochloride targets the genes DRD2, HTR3A, and HTR4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%metoclopramide hydrochloride%" OR LOWER(tradeName... | [{'UUID': 'DrugTargetsIndication121923_text_199701', 'drugName': 'Metoclopramide Hydrochloride', 'tradeNames_list': '[\'"clopra-""yellow"""\', \'Clopra\', \'Clopra-"Yellow"\', \'Gastrese l.a.Gastrobid continus\', \'Gastroflux\', \'Gastromax\', \'Gimoti\', \'MaxolonMaxolon sr\', \'Metoclomex\', \'Metoclopramide hydrochl... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.440 | Q6 | What genes does Linagliptin target when it's used to treat COVID-19? | Linagliptin has not been approved by the FDA as a treatment for COVID-19, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is DPP4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%linagliptin%" OR LOWER(tradeNames_list) LIKE "%li... | [{'UUID': 'DrugTargetsIndication121923_text_932955', 'drugName': 'Linagliptin', 'tradeNames_list': "['Tradjenta', 'Trajenta']", 'syns_list': "['BI 1356', 'BI 1356 BS', 'BI-1356', 'BI-1356-BS', 'BI-1356BS', 'BS 1356 BSBS-1356-BS', 'Linagliptin', 'Trazenta']", 'target': 'ENSG00000197635', 'approvedSymbol': 'DPP4', 'appro... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.77 | Q6 | What genes does Halobetasol Propionate target when it's used to treat atopic eczema? | Halobetasol Propionate has not been approved by the FDA as a treatment for atopic eczema, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%halobetasol propionate%" OR LOWER(tradeNames_list... | [{'UUID': 'DrugTargetsIndication121923_text_240738', 'drugName': 'Halobetasol Propionate', 'tradeNames_list': "['Bryhali', 'Halobetasol propionate', 'Lexette', 'Ultravate']", 'syns_list': "['21-chloro diflorasone', 'BMY-30056', 'CGP-14,458', 'CGP-14458Halobetasol', 'Halobetasol propionate', 'IDP-122', 'Jemdel', 'Ulobet... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1793 | Q6 | What genes does Latanoprost target when it's used to treat hypertension? | When used to treat hypertension, the drug Latanoprost targets the gene PTGFR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%latanoprost%" OR LOWER(tradeNames_list) LIKE "%la... | [{'UUID': 'DrugTargetsIndication121923_text_1149119', 'drugName': 'Latanoprost', 'tradeNames_list': "['Latanoprost', 'Monopost', 'Xalatan', 'Xelpros']", 'syns_list': "['Latanoprost', 'Latanoprost (isopropyl ester)', 'PHXA-41', 'PHXA41', 'T-2345T2345', 'XA-41', 'XA41']", 'target': 'ENSG00000122420', 'approvedSymbol': 'P... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1462 | Q6 | What genes does Dasatinib target when it's used to treat head and neck squamous cell carcinoma? | Dasatinib has not been approved by the FDA as a treatment for head and neck squamous cell carcinoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are ABL1, BCR, HCK, SRC, LYN, KIT, PDGFRB, EPHA2, FRK, FYN, LCK, YES1, BLK, FGR, and SRMS. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dasatinib%" OR LOWER(tradeNames_list) LIKE "%dasa... | [{'UUID': 'DrugTargetsIndication121923_text_713556', 'drugName': 'Dasatinib', 'tradeNames_list': "['Dasatinib', 'Sprycel']", 'syns_list': "['BMS-354825', 'BMS-354825 HYDRATE', 'BMS-354825-03', 'DasatinibDasatinib anhydrous', 'Dasatinib hydrate', 'Dasatinib monohydrateNSC-759877']", 'target': 'ENSG00000097007', 'approve... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.926 | Q6 | What genes does Istradefylline target when it's used to treat drug dependence? | Istradefylline has not been approved by the FDA as a treatment for drug dependence, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is ADORA2A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%istradefylline%" OR LOWER(tradeNames_list) LIKE "... | [{'UUID': 'DrugTargetsIndication121923_text_695357', 'drugName': 'Istradefylline', 'tradeNames_list': "['Nourianz']", 'syns_list': "['Istradefylline', 'KW-6002', 'Nouriast']", 'target': 'ENSG00000128271', 'approvedSymbol': 'ADORA2A', 'approvedName': 'adenosine A2a receptor', 'mesh_heading': 'Substance-Related Disorders... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1712 | Q6 | What genes does Cabozantinib S-Malate target when it's used to treat adrenal gland pheochromocytoma? | Cabozantinib S-Malate has not been approved by the FDA as a treatment for adrenal gland pheochromocytoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are KDR and MET. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%cabozantinib s-malate%" OR LOWER(tradeNames_list)... | [{'UUID': 'DrugTargetsIndication121923_text_669659', 'drugName': 'Cabozantinib S-Malate', 'tradeNames_list': "['Cabometyx', 'Cometriq']", 'syns_list': "['BMS-907351', 'Cabozantinib malate', 'Cabozantinib s-malate', 'XL-184XL184']", 'target': 'ENSG00000128052', 'approvedSymbol': 'KDR', 'approvedName': 'kinase insert dom... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1671 | Q6 | What genes does Fluocinolone Acetonide target when it's used to treat skin disease? | When used to treat skin disease, the drug Fluocinolone Acetonide targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fluocinolone acetonide%" OR LOWER(tradeNames_list... | [{'UUID': 'DrugTargetsIndication121923_text_242235', 'drugName': 'Fluocinolone Acetonide', 'tradeNames_list': "['Capex', 'Derma-smoothe/fs', 'Dermotic', 'Fluocet', 'Fluocinolone acetonideFluonid', 'Fluotrex', 'Fs shampoo', 'Iluvien', 'Retisert', 'SynalarSynalar fte', 'Synalar-c', 'Synalar-hp', 'Synalar-n', 'Synandone',... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1621 | Q6 | What genes does Dasatinib target when it's used to treat melanoma? | Dasatinib has not been approved by the FDA as a treatment for melanoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are ABL1, BCR, HCK, SRC, LYN, KIT, PDGFRB, EPHA2, FRK, FYN, LCK, YES1, BLK, FGR, and SRMS. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dasatinib%" OR LOWER(tradeNames_list) LIKE "%dasa... | [{'UUID': 'DrugTargetsIndication121923_text_713259', 'drugName': 'Dasatinib', 'tradeNames_list': "['Dasatinib', 'Sprycel']", 'syns_list': "['BMS-354825', 'BMS-354825 HYDRATE', 'BMS-354825-03', 'DasatinibDasatinib anhydrous', 'Dasatinib hydrate', 'Dasatinib monohydrateNSC-759877']", 'target': 'ENSG00000097007', 'approve... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.769 | Q6 | What genes does Glucagon target when it's used to treat diabetes mellitus? | When used to treat diabetes mellitus, the drug Glucagon targets the gene GCGR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%glucagon%" OR LOWER(tradeNames_list) LIKE "%gluca... | [{'UUID': 'DrugTargetsIndication121923_text_968349', 'drugName': 'Glucagon', 'tradeNames_list': "['Baqsimi', 'Glucagen Hypokit', 'Glucagon', 'Glucagon Emergency KitGvoke hypopen', 'Gvoke pfs']", 'syns_list': "['Glucagon', 'Glucagon recombinant']", 'target': 'ENSG00000215644', 'approvedSymbol': 'GCGR', 'approvedName': '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.998 | Q6 | What genes does Belzutifan target when it's used to treat hemangioblastoma? | When used to treat hemangioblastoma, the drug Belzutifan targets the gene EPAS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%belzutifan%" OR LOWER(tradeNames_list) LIKE "%bel... | [{'UUID': 'DrugTargetsIndication121923_text_1192115', 'drugName': 'Belzutifan', 'tradeNames_list': "['Welireg']", 'syns_list': "['Belzutifan', 'MK-6482', 'MK6482', 'Mk-6482', 'PT-2977', 'PT2977', 'Pt 2977Pt2977']", 'target': 'ENSG00000116016', 'approvedSymbol': 'EPAS1', 'approvedName': 'endothelial PAS domain protein 1... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.394 | Q6 | What genes does Paliperidone Palmitate target when it's used to treat schizophrenia? | When used to treat schizophrenia, the drug Paliperidone Palmitate targets the genes DRD2 and HTR2A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%paliperidone palmitate%" OR LOWER(tradeNames_list... | [{'UUID': 'DrugTargetsIndication121923_text_197439', 'drugName': 'Paliperidone Palmitate', 'tradeNames_list': "['Invega hafyera', 'Invega sustenna', 'Invega trinza']", 'syns_list': "['JNS-010', 'JNS010', 'Paliperidone palmitate', 'Palperidone palmitateR-092670', 'R092670', 'RO-92670', 'RO92670']", 'target': 'ENSG000001... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.238 | Q6 | What genes does Topiramate target when it's used to treat Lennox-Gastaut syndrome? | When used to treat Lennox-Gastaut syndrome, the drug Topiramate targets the genes SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, SCN10A, CA2, CA4, GABRA1, GABRB2, GABRG2, GABRB3, GABRA4, GABRG3, GABRQ, GABRA3, GABRP, GABRD, GABRG1, GABRB1, GABRE, GABRA2, GABRA5, GABRA6, GRIK1, GRIK5, GRIK4, GRIK2, GRIK... | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%topiramate%" OR LOWER(tradeNames_list) LIKE "%top... | [{'UUID': 'DrugTargetsIndication121923_text_457465', 'drugName': 'Topiramate', 'tradeNames_list': "['Epitomax', 'Eprontia', 'Qudexy xr', 'Topamax', 'Topamax sprinkleTopiramate', 'Trokendi xr']", 'syns_list': "['(-)-topiramate', 'Epitoma', 'Eprontia', 'MCN-4853', 'Qudexy', 'RWJ-17021RWJ-17021-000', 'Sincronil', 'Topamac... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1508 | Q6 | What genes does Cannabidiol target when it's used to treat Dravet syndrome? | When used to treat Dravet syndrome, the drug Cannabidiol targets the gene CNR1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%cannabidiol%" OR LOWER(tradeNames_list) LIKE "%ca... | [{'UUID': 'DrugTargetsIndication121923_text_1073765', 'drugName': 'Cannabidiol', 'tradeNames_list': "['Epidiolex']", 'syns_list': "['(-)-cannabidiol', '(-)-cbd', '(-)-trans-cannabidiol.delta.1(2)-trans-cannabidiol', 'BTX-1204', 'BTX-1503', 'CBD', 'CannabidiolCannabidiol solution', 'Cardiolrx', 'GWP-42003', 'GWP-42003-P... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.270 | Q6 | What genes does Paclitaxel target when it's used to treat breast carcinoma? | When used to treat breast carcinoma, the drug Paclitaxel targets the genes TUBB4B, TUBB1, TUBA3C, TUBA4A, TUBB3, TUBA1A, TUBB4A, TUBB8, TUBB, TUBA1B, TUBA1C, TUBA3E, TUBB2A, TUBB2B, and TUBB6. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%paclitaxel%" OR LOWER(tradeNames_list) LIKE "%pac... | [{'UUID': 'DrugTargetsIndication121923_text_11381', 'drugName': 'Paclitaxel', 'tradeNames_list': "['Abraxane', 'Pacitaxel', 'Paclitaxel', 'Paxene', 'Taxol', 'Taxol 100']", 'syns_list': "['(-)-paclitaxel', 'ABI-007', 'ABI-007 COMPONENT PACLITAXEL', 'BMS 181339-01BMS-181339-01', 'Capxol', 'Cyclopax', 'DHP 107', 'DHP-107'... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1187 | Q6 | What genes does Buprenorphine target when it's used to treat opioid dependence? | When used to treat opioid dependence, the drug Buprenorphine targets the genes OPRM1 and OPRK1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%buprenorphine%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_764505', 'drugName': 'Buprenorphine', 'tradeNames_list': "['Bupeaze', 'Buplast', 'Butec', 'Butrans', 'Hapoctasin', 'Panitaz', 'PrenotrixReletrans', 'Sevodyne', 'Sublocade', 'Temgesic', 'Tephine', 'Transtec']", 'syns_list': "['ALKS-5461 COMPONENT BUPRENORPHINE', 'Brixadi', 'Bu... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.120 | Q6 | What genes does Duvelisib target when it's used to treat Sezary's disease? | Duvelisib has not been approved by the FDA as a treatment for Sezary's disease, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are PIK3CD and PIK3CG. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%duvelisib%" OR LOWER(tradeNames_list) LIKE "%duve... | [{'UUID': 'DrugTargetsIndication121923_text_858825', 'drugName': 'Duvelisib', 'tradeNames_list': "['Copiktra']", 'syns_list': "['Duvelisib', 'Duvelisib hydrate', 'Duvelisib monohydrate', 'INK-1147INK-1197', 'IPI-145']", 'target': 'ENSG00000171608', 'approvedSymbol': 'PIK3CD', 'approvedName': 'phosphatidylinositol-4,5-b... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1607 | Q6 | What genes does Duvelisib target when it's used to treat chronic lymphocytic leukemia? | When used to treat chronic lymphocytic leukemia, the drug Duvelisib targets the genes PIK3CD and PIK3CG. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%duvelisib%" OR LOWER(tradeNames_list) LIKE "%duve... | [{'UUID': 'DrugTargetsIndication121923_text_858835', 'drugName': 'Duvelisib', 'tradeNames_list': "['Copiktra']", 'syns_list': "['Duvelisib', 'Duvelisib hydrate', 'Duvelisib monohydrate', 'INK-1147INK-1197', 'IPI-145']", 'target': 'ENSG00000171608', 'approvedSymbol': 'PIK3CD', 'approvedName': 'phosphatidylinositol-4,5-b... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.680 | Q6 | What genes does Pemetrexed Disodium target when it's used to treat gestational trophoblastic neoplasm? | Pemetrexed Disodium has not been approved by the FDA as a treatment for gestational trophoblastic neoplasm, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are TYMS, GART, and DHFR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%pemetrexed disodium%" OR LOWER(tradeNames_list) L... | [{'UUID': 'DrugTargetsIndication121923_text_918411', 'drugName': 'Pemetrexed Disodium', 'tradeNames_list': "['Alimta']", 'syns_list': "['LY-231514 DISODIUM SALT', 'LY231514 DISODIUM SALT', 'Pemetrexed disodiumPemetrexed disodium heptahydrate', 'Pemetrexed sodium hydratePemetrexed sodium salt']", 'target': 'ENSG00000228... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.252 | Q6 | What genes does Dexamethasone target when it's used to treat keratitis? | When used to treat keratitis, the drug Dexamethasone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dexamethasone%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_227779', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1958 | Q6 | What genes does Cyclosporine target when it's used to treat COVID-19? | Cyclosporine has not been approved by the FDA as a treatment for COVID-19, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is PPIA. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%cyclosporine%" OR LOWER(tradeNames_list) LIKE "%c... | [{'UUID': 'DrugTargetsIndication121923_text_1101226', 'drugName': 'Cyclosporine', 'tradeNames_list': "['Capimune', 'Capsorin', 'Cequa', 'Cyclosporine', 'Deximune', 'GengrafIkervis', 'Neoral', 'Optimmune', 'Restasis', 'Restasis multidoseSandimmun', 'Sandimmune', 'Sangcya', 'Vanquoral', 'Verkazia']", 'syns_list': "['27-4... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1995 | Q6 | What genes does Famotidine target when it's used to treat gastric ulcer? | When used to treat gastric ulcer, the drug Famotidine targets the gene HRH2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%famotidine%" OR LOWER(tradeNames_list) LIKE "%fam... | [{'UUID': 'DrugTargetsIndication121923_text_1100338', 'drugName': 'Famotidine', 'tradeNames_list': "['Famotidine', 'Famotidine preservative freeFamotidine preservative free (pharmacy bulk)', 'Fluxid', 'PepcidPepcid ac', 'Pepcid preservative free', 'Pepcid rpd']", 'syns_list': "['Amfamox', 'Fadul', 'Famodil', 'Famosan',... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.97 | Q6 | What genes does Fentanyl Citrate target when it's used to treat pain? | When used to treat pain, the drug Fentanyl Citrate targets the gene OPRM1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fentanyl citrate%" OR LOWER(tradeNames_list) LIKE... | [{'UUID': 'DrugTargetsIndication121923_text_785366', 'drugName': 'Fentanyl Citrate', 'tradeNames_list': "['Abstral', 'Actiq', 'Fentanyl', 'Fentanyl citrateFentanyl citrate preservative free', 'Fentora', 'Lazanda', 'OnsolisSublimaze', 'Sublimaze preservative free', 'Thalamonal']", 'syns_list': "['Fentanyl buccal', 'Fent... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.34 | Q6 | What genes does Fluocinolone Acetonide target when it's used to treat psoriasis? | When used to treat psoriasis, the drug Fluocinolone Acetonide targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fluocinolone acetonide%" OR LOWER(tradeNames_list... | [{'UUID': 'DrugTargetsIndication121923_text_242234', 'drugName': 'Fluocinolone Acetonide', 'tradeNames_list': "['Capex', 'Derma-smoothe/fs', 'Dermotic', 'Fluocet', 'Fluocinolone acetonideFluonid', 'Fluotrex', 'Fs shampoo', 'Iluvien', 'Retisert', 'SynalarSynalar fte', 'Synalar-c', 'Synalar-hp', 'Synalar-n', 'Synandone',... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1465 | Q6 | What genes does Celecoxib target when it's used to treat migraine disorder? | When used to treat migraine disorder, the drug Celecoxib targets the gene PTGS2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%celecoxib%" OR LOWER(tradeNames_list) LIKE "%cele... | [{'UUID': 'DrugTargetsIndication121923_text_833506', 'drugName': 'Celecoxib', 'tradeNames_list': "['Celebra', 'Celebrex', 'Celecoxib', 'Elyxyb', 'Onsenal']", 'syns_list': "['Celecoxib', 'DFN-15', 'DFN15', 'NSC-719627', 'NSC-758624', 'SC-58635']", 'target': 'ENSG00000073756', 'approvedSymbol': 'PTGS2', 'approvedName': '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1668 | Q6 | What genes does Dexamethasone target when it's used to treat bursitis? | When used to treat bursitis, the drug Dexamethasone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dexamethasone%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_226946', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.454 | Q6 | What genes does Amantadine Hydrochloride target when it's used to treat secondary Parkinson disease? | When used to treat secondary Parkinson disease, the drug Amantadine Hydrochloride targets the genes GRIN1, GRIN2A, GRIN2B, GRIN2D, GRIN3B, GRIN2C, and GRIN3A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%amantadine hydrochloride%" OR LOWER(tradeNames_li... | [{'UUID': 'DrugTargetsIndication121923_text_441092', 'drugName': 'Amantadine Hydrochloride', 'tradeNames_list': "['Amantadine hydrochloride', 'Gocovri', 'Lysovir', 'Mantadine', 'Osmolex erSymadine', 'Symmetrel']", 'syns_list': "['Adamantanamine hydrochloride', 'Amantadine hclAmantadine hydrochloride', 'EXP-105-1', 'Man... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.723 | Q6 | What genes does Olodaterol Hydrochloride target when it's used to treat chronic bronchitis? | When used to treat chronic bronchitis, the drug Olodaterol Hydrochloride targets the gene ADRB2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%olodaterol hydrochloride%" OR LOWER(tradeNames_li... | [{'UUID': 'DrugTargetsIndication121923_text_937112', 'drugName': 'Olodaterol Hydrochloride', 'tradeNames_list': "['Striverdi respimat']", 'syns_list': "['BI 1744 CL', 'BI-1744 CL', 'BI-1744-CL', 'Olodaterol hydrochloride']", 'target': 'ENSG00000169252', 'approvedSymbol': 'ADRB2', 'approvedName': 'adrenoceptor beta 2', ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1261 | Q6 | What genes does Desmopressin Acetate target when it's used to treat diabetes insipidus? | When used to treat diabetes insipidus, the drug Desmopressin Acetate targets the genes AVPR2, AVPR1A, and AVPR1B. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%desmopressin acetate%" OR LOWER(tradeNames_list) ... | [{'UUID': 'DrugTargetsIndication121923_text_694421', 'drugName': 'Desmopressin Acetate', 'tradeNames_list': "['Concentraid', 'Ddavp', 'Ddavp (needs no refrigeration)', 'DesmomeltDesmopressin acetate', 'Desmopressin acetate (needs no refrigeration)Desmopressin acetate preservative free', 'Desmospray', 'DesmotabsMinirin'... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1598 | Q6 | What genes does Prednisone target when it's used to treat adrenocortical insufficiency? | Prednisone has not been approved by the FDA as a treatment for adrenocortical insufficiency, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%prednisone%" OR LOWER(tradeNames_list) LIKE "%pre... | [{'UUID': 'DrugTargetsIndication121923_text_218569', 'drugName': 'Prednisone', 'tradeNames_list': "['Cortan', 'Cortancyl', 'Decortisyl', 'Delta-dome', 'Deltasone', 'FernisoneLiquid pred', 'Lodotra', 'Meticorten', 'Orasone', 'Paracort', 'Prednicen-mPrednisone', 'Prednisone intensol', 'Rayos', 'Servisone', 'Sterapred']",... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1 | Q6 | What genes does Bosentan target when it's used to treat chronic obstructive pulmonary disease? | Bosentan has not been approved by the FDA as a treatment for chronic obstructive pulmonary disease, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are EDNRA and EDNRB. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%bosentan%" OR LOWER(tradeNames_list) LIKE "%bosen... | [{'UUID': 'DrugTargetsIndication121923_text_1084219', 'drugName': 'Bosentan', 'tradeNames_list': "['Tracleer']", 'syns_list': "['Anhydrous bosentan', 'Bosentan', 'Bosentan anhydrous', 'Bosentan hydrateBosentan monohydrate', 'RO 47-0203/029', 'RO-47-0203-029', 'RO-470203029']", 'target': 'ENSG00000151617', 'approvedSymb... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1377 | Q6 | What genes does Dexamethasone target when it's used to treat eosinophilic pneumonia? | When used to treat eosinophilic pneumonia, the drug Dexamethasone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dexamethasone%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_227774', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1110 | Q6 | What genes does Prednisone target when it's used to treat contact dermatitis? | When used to treat contact dermatitis, the drug Prednisone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%prednisone%" OR LOWER(tradeNames_list) LIKE "%pre... | [{'UUID': 'DrugTargetsIndication121923_text_218687', 'drugName': 'Prednisone', 'tradeNames_list': "['Cortan', 'Cortancyl', 'Decortisyl', 'Delta-dome', 'Deltasone', 'FernisoneLiquid pred', 'Lodotra', 'Meticorten', 'Orasone', 'Paracort', 'Prednicen-mPrednisone', 'Prednisone intensol', 'Rayos', 'Servisone', 'Sterapred']",... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1117 | Q6 | What genes does Erlosamide target when it's used to treat central nervous system cancer? | Erlosamide has not been approved by the FDA as a treatment for central nervous system cancer, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%erlosamide%" OR LOWER(tradeNames_list) LIKE "%erl... | [{'UUID': 'DrugTargetsIndication121923_text_644699', 'drugName': 'Erlosamide', 'tradeNames_list': "['Lacosamide', 'Vimpat']", 'syns_list': "['(r)-lacosamide 1', 'ADD 243037', 'ADD-243037', 'Erlosamide', 'LacosamideLacosamide cv', 'SPM 927', 'SPM-927']", 'target': 'ENSG00000144285', 'approvedSymbol': 'SCN1A', 'approvedN... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1591 | Q6 | What genes does Montelukast target when it's used to treat Dengue Hemorrhagic Fever? | Montelukast has not been approved by the FDA as a treatment for Dengue Hemorrhagic Fever, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is CYSLTR1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%montelukast%" OR LOWER(tradeNames_list) LIKE "%mo... | [{'UUID': 'DrugTargetsIndication121923_text_1100409', 'drugName': 'Montelukast', 'tradeNames_list': "['Singulair']", 'syns_list': "['Brondilat', 'MK-476', 'Montelukast']", 'target': 'ENSG00000173198', 'approvedSymbol': 'CYSLTR1', 'approvedName': 'cysteinyl leukotriene receptor 1', 'mesh_heading': 'Severe Dengue', 'efo_... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.85 | Q6 | What genes does Ixabepilone target when it's used to treat urinary bladder carcinoma? | Ixabepilone has not been approved by the FDA as a treatment for urinary bladder carcinoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are TUBB4B, TUBB1, TUBA3C, TUBA4A, TUBB3, TUBA1A, TUBB4A, TUBB8, TUBB, TUBA1B, TUBA1C, TUBA3E, TUBB2A, TUBB2B, and TUBB6. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ixabepilone%" OR LOWER(tradeNames_list) LIKE "%ix... | [{'UUID': 'DrugTargetsIndication121923_text_85063', 'drugName': 'Ixabepilone', 'tradeNames_list': "['Ixempra', 'Ixempra kit']", 'syns_list': "['Azaepothilone b', 'BMS 247550-01', 'BMS-247550', 'BMS-247550-01Ixabepilone', 'Ixempra', 'NSC-747973']", 'target': 'ENSG00000188229', 'approvedSymbol': 'TUBB4B', 'approvedName':... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1294 | Q6 | What genes does Lomitapide Mesylate target when it's used to treat homozygous familial hypercholesterolemia? | When used to treat homozygous familial hypercholesterolemia, the drug Lomitapide Mesylate targets the genes MTTP and P4HB. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lomitapide mesylate%" OR LOWER(tradeNames_list) L... | [{'UUID': 'DrugTargetsIndication121923_text_1042968', 'drugName': 'Lomitapide Mesylate', 'tradeNames_list': "['Juxtapid']", 'syns_list': "['AEGR-733', 'AEGR-733 MESYLATE', 'Aegr-733 mesilate', 'BMS-201038BMS-201038-04', 'Lomitapide mesilate', 'Lomitapide mesylate']", 'target': 'ENSG00000138823', 'approvedSymbol': 'MTTP... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.683 | Q6 | What genes does Zoledronic Acid target when it's used to treat Paget disease? | When used to treat Paget disease, the drug Zoledronic Acid targets the gene FDPS. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%zoledronic acid%" OR LOWER(tradeNames_list) LIKE ... | [{'UUID': 'DrugTargetsIndication121923_text_1099884', 'drugName': 'Zoledronic Acid', 'tradeNames_list': "['Aclasta', 'Reclast', 'Zerlinda', 'Zoledronic acid', 'Zometa']", 'syns_list': "['AK-156', 'Anhydrous zoledronic acid', 'CGP 42446', 'CGP-42446', 'CGP-42446ANSC-721517', 'Zoladrona acid mylan', 'Zoledronate', 'Zoled... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1677 | Q6 | What genes does Aspirin target when it's used to treat pain? | When used to treat pain, the drug Aspirin targets the genes PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%aspirin%" OR LOWER(tradeNames_list) LIKE "%aspiri... | [{'UUID': 'DrugTargetsIndication121923_text_835527', 'drugName': 'Aspirin', 'tradeNames_list': "['8-hour bayer', 'Acetosalic Acid', 'Acetylsalic acidAcetylsalicylic Acid', 'Alka rapid', 'Anadin all night', 'Angettes 75Aspirin', 'Aspro clr', 'Bayer extra strength aspirin for migraine painDanamep', 'Disprin cv', 'Disprin... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1055 | Q6 | What genes does Prednisone target when it's used to treat viral pneumonia? | Prednisone has not been approved by the FDA as a treatment for viral pneumonia, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%prednisone%" OR LOWER(tradeNames_list) LIKE "%pre... | [{'UUID': 'DrugTargetsIndication121923_text_218566', 'drugName': 'Prednisone', 'tradeNames_list': "['Cortan', 'Cortancyl', 'Decortisyl', 'Delta-dome', 'Deltasone', 'FernisoneLiquid pred', 'Lodotra', 'Meticorten', 'Orasone', 'Paracort', 'Prednicen-mPrednisone', 'Prednisone intensol', 'Rayos', 'Servisone', 'Sterapred']",... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.777 | Q6 | What genes does Celecoxib target when it's used to treat rectum cancer? | Celecoxib has not been approved by the FDA as a treatment for rectum cancer, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is PTGS2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%celecoxib%" OR LOWER(tradeNames_list) LIKE "%cele... | [{'UUID': 'DrugTargetsIndication121923_text_833476', 'drugName': 'Celecoxib', 'tradeNames_list': "['Celebra', 'Celebrex', 'Celecoxib', 'Elyxyb', 'Onsenal']", 'syns_list': "['Celecoxib', 'DFN-15', 'DFN15', 'NSC-719627', 'NSC-758624', 'SC-58635']", 'target': 'ENSG00000073756', 'approvedSymbol': 'PTGS2', 'approvedName': '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1289 | Q6 | What genes does Lidocaine target when it's used to treat pain? | When used to treat pain, the drug Lidocaine targets the genes SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lidocaine%" OR LOWER(tradeNames_list) LIKE "%lido... | [{'UUID': 'DrugTargetsIndication121923_text_637893', 'drugName': 'Lidocaine', 'tradeNames_list': "['Alphacaine', 'Anestacon', 'Dentipatch', 'Lidocaine', 'LidodermLignocaine Hcl', 'Lignostab', 'Lmx 4', 'Oraqix', 'Vagisil', 'XylocaineXylodase', 'Xylotox', 'Ztlido']", 'syns_list': "['ALGRX 3268', 'ALGRX-3268', 'Anestacon'... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1946 | Q6 | What genes does Nitroglycerin target when it's used to treat angina pectoris? | When used to treat angina pectoris, the drug Nitroglycerin targets the genes GUCY1B1, GUCY1B2, GUCY1A2, and GUCY1A1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%nitroglycerin%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_972651', 'drugName': 'Nitroglycerin', 'tradeNames_list': "['Coro-nitro', 'Deponit 10', 'Deponit 5', 'Glytrin', 'Gonitro', 'Lenitral 7.5Minitran', 'Minitran 10', 'Minitran 15', 'Minitran 5', 'NatiroseNitriderm tts', 'Nitro iv', 'Nitro-bid', 'Nitro-dur', 'Nitro-mack retNitrocin... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1581 | Q6 | What genes does Ixabepilone target when it's used to treat breast neoplasm? | When used to treat breast neoplasm, the drug Ixabepilone targets the genes TUBB4B, TUBB1, TUBA3C, TUBA4A, TUBB3, TUBA1A, TUBB4A, TUBB8, TUBB, TUBA1B, TUBA1C, TUBA3E, TUBB2A, TUBB2B, and TUBB6. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ixabepilone%" OR LOWER(tradeNames_list) LIKE "%ix... | [{'UUID': 'DrugTargetsIndication121923_text_85776', 'drugName': 'Ixabepilone', 'tradeNames_list': "['Ixempra', 'Ixempra kit']", 'syns_list': "['Azaepothilone b', 'BMS 247550-01', 'BMS-247550', 'BMS-247550-01Ixabepilone', 'Ixempra', 'NSC-747973']", 'target': 'ENSG00000101162', 'approvedSymbol': 'TUBB1', 'approvedName': ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1490 | Q6 | What genes does Lemborexant target when it's used to treat insomnia? | When used to treat insomnia, the drug Lemborexant targets the genes HCRTR2 and HCRTR1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lemborexant%" OR LOWER(tradeNames_list) LIKE "%le... | [{'UUID': 'DrugTargetsIndication121923_text_1076427', 'drugName': 'Lemborexant', 'tradeNames_list': "['Dayvigo']", 'syns_list': "['E-2006', 'E2006', 'Lemborexant']", 'target': 'ENSG00000121764', 'approvedSymbol': 'HCRTR1', 'approvedName': 'hypocretin receptor 1', 'mesh_heading': 'Sleep Initiation and Maintenance Disord... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.410 | Q6 | What genes does Zoledronic Acid target when it's used to treat prostate adenocarcinoma? | When used to treat prostate adenocarcinoma, the drug Zoledronic Acid targets the gene FDPS. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%zoledronic acid%" OR LOWER(tradeNames_list) LIKE ... | [{'UUID': 'DrugTargetsIndication121923_text_1099874', 'drugName': 'Zoledronic Acid', 'tradeNames_list': "['Aclasta', 'Reclast', 'Zerlinda', 'Zoledronic acid', 'Zometa']", 'syns_list': "['AK-156', 'Anhydrous zoledronic acid', 'CGP 42446', 'CGP-42446', 'CGP-42446ANSC-721517', 'Zoladrona acid mylan', 'Zoledronate', 'Zoled... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1728 | Q6 | What genes does Cinacalcet target when it's used to treat parathyroid disease? | When used to treat parathyroid disease, the drug Cinacalcet targets the gene CASR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%cinacalcet%" OR LOWER(tradeNames_list) LIKE "%cin... | [{'UUID': 'DrugTargetsIndication121923_text_1149085', 'drugName': 'Cinacalcet', 'tradeNames_list': "['Sensipar']", 'syns_list': "['AMG 073', 'AMG-073', 'AMG073', 'Cinacalcet', 'KRN-1493', 'KRN1493']", 'target': 'ENSG00000036828', 'approvedSymbol': 'CASR', 'approvedName': 'calcium sensing receptor', 'mesh_heading': 'Par... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1298 | Q6 | What genes does Carbamazepine target when it's used to treat Chemotherapy-induced nausea and vomiting? | Carbamazepine has not been approved by the FDA as a treatment for Chemotherapy-induced nausea and vomiting, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%carbamazepine%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_650975', 'drugName': 'Carbamazepine', 'tradeNames_list': "['Arbil mr', 'Carbagen sr', 'Carbamazepine', 'Carbatrol', 'Carnexiv', 'EpimazEpimaz ret', 'Epitol', 'Equetro', 'Sirtal ret', 'Tegretol', 'Tegretol XrTegretol chewtab', 'Tegretol prolonged release', 'Tegretol-xr', 'Teri... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1665 | Q6 | What genes does Pomalidomide target when it's used to treat immune system disease? | When used to treat immune system disease, the drug Pomalidomide targets the genes CRBN, DDB1, CUL4A, and RBX1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%pomalidomide%" OR LOWER(tradeNames_list) LIKE "%p... | [{'UUID': 'DrugTargetsIndication121923_text_1141327', 'drugName': 'Pomalidomide', 'tradeNames_list': "['Imnovid', 'Pomalyst']", 'syns_list': "['Actimid', 'CC-4047', 'IMID 3', 'IMID-3', 'Pomalidomide']", 'target': 'ENSG00000113851', 'approvedSymbol': 'CRBN', 'approvedName': 'cereblon', 'mesh_heading': 'Immune System Dis... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
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