uuid stringlengths 4 8 | template_uuid stringclasses 40
values | question stringlengths 13 193 | answer stringlengths 29 2.2k | benchmark_query stringlengths 133 622 | execution_results stringlengths 2 1.14M | query_type stringclasses 2
values | sql_category stringclasses 26
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Q67.343 | Q67 | What is the top-associated SNP of the gene RP11-707O23.5 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for RP11-707O23.5 in Whole Brain meta-analysis mQTL omic data for AD is rs62066086, which has a multi-SNP SMR p-value of 2.93e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-707O23.5" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_115148', 'topRSID': 'rs62066086', 'Disease': 'AD', 'Gene': 'RP11-707O23.5', 'p_SMR_multi': 5.929465e-07, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of link... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.626 | Q67 | What is the top-associated SNP of the gene GPNMB in Nucleus Accumbens Basal Ganglia omic data for PD and is it functionally significant? | The top-associated SNP for GPNMB in Nucleus Accumbens Basal Ganglia omic data for PD is rs199357, which has a multi-SNP SMR p-value of 8.08e-07 and a HEIDI of 0.1, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "GPNMB" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%nucleus accumbens basal ganglia%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1728685', 'topRSID': 'rs199357', 'Disease': 'PD', 'Gene': 'GPNMB', 'p_SMR_multi': 8.078376e-07, 'p_HEIDI': 0.1004834, 'Omic_tissue': 'Nucleus Accumbens Basal', 'Omic_type': 'Nucleus Accumbens Basal Ganglia', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.484 | Q67 | What is the top-associated SNP of the gene MARK4 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for MARK4 in Whole Brain meta-analysis mQTL omic data for AD is rs2041262, which has a multi-SNP SMR p-value of 1.18e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MARK4" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_122480', 'topRSID': 'rs2041262', 'Disease': 'AD', 'Gene': 'MARK4', 'p_SMR_multi': 1.177207e-06, 'p_HEIDI': 1.210811e-12, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.532 | Q67 | What is the top-associated SNP of the gene RP11-707O23.5 in Prefrontal Cortex eQTL omic data for PD and is it functionally significant? | The top-associated SNP for RP11-707O23.5 in Prefrontal Cortex eQTL omic data for PD is rs2732615, which has a multi-SNP SMR p-value of 3.43e-16 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-707O23.5" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%prefrontal cortex eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1242267', 'topRSID': 'rs2732615', 'Disease': 'PD', 'Gene': 'RP11-707O23.5', 'p_SMR_multi': 3.426591e-16, 'p_HEIDI': 0.0001637904, 'Omic_tissue': 'Prefrontal Cortex', 'Omic_type': 'Prefrontal Cortex eQTL', 'func_sig': 'association meets significance threshold but shows signs of l... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.268 | Q67 | What is the top-associated SNP of the gene KLHL7-AS1 in Frontal Cortex BA9 eQTL omic data for PD and is it functionally significant? | The top-associated SNP for KLHL7-AS1 in Frontal Cortex BA9 eQTL omic data for PD is rs10256524, which has a multi-SNP SMR p-value of 4.74e-07 and a HEIDI of 0.01, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KLHL7-AS1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%frontal cortex ba9 eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1167541', 'topRSID': 'rs10256524', 'Disease': 'PD', 'Gene': 'KLHL7-AS1', 'p_SMR_multi': 4.735275e-07, 'p_HEIDI': 0.0127584, 'Omic_tissue': 'Frontal Cortex', 'Omic_type': 'Frontal Cortex BA9 eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1390 | Q67 | What is the top-associated SNP of the gene RP11-254F7.2 in Hippocampus eQTL omic data for AD and is it functionally significant? | There are no SNPs within the gene RP11-254F7.2 in Hippocampus eQTL omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-254F7.2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%hippocampus eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1377034', 'topRSID': 'rs74416754', 'Disease': 'AD', 'Gene': 'RP11-254F7.2', 'p_SMR_multi': 0.2956899, 'p_HEIDI': 0.7244377, 'Omic_tissue': 'Hippocampus', 'Omic_type': 'Hippocampus eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.681 | Q67 | What is the top-associated SNP of the gene LRRC37A4P in Hippocampus eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for LRRC37A4P in Hippocampus eQTL omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 1.10e-19 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A4P" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%hippocampus eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1388478', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'LRRC37A4P', 'p_SMR_multi': 1.096563e-19, 'p_HEIDI': 9.508503e-24, 'Omic_tissue': 'Hippocampus', 'Omic_type': 'Hippocampus eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.492 | Q67 | What is the top-associated SNP of the gene LRRC37A4P in Liver eQTL omic data for PD and is it functionally significant? | The top-associated SNP for LRRC37A4P in Liver eQTL omic data for PD is rs2942166, which has a multi-SNP SMR p-value of 1.63e-12 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A4P" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%liver eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1476420', 'topRSID': 'rs2942166', 'Disease': 'PD', 'Gene': 'LRRC37A4P', 'p_SMR_multi': 1.630765e-12, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Liver', 'Omic_type': 'Liver eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.445 | Q67 | What is the top-associated SNP of the gene EPHA1 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for EPHA1 in Whole Blood mQTL omic data for AD is rs3935067, which has a multi-SNP SMR p-value of 2.43e-07 and a HEIDI of 0.03, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "EPHA1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_587066', 'topRSID': 'rs3935067', 'Disease': 'AD', 'Gene': 'EPHA1', 'p_SMR_multi': 4.179099e-08, 'p_HEIDI': 0.0007605525, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.274 | Q67 | What is the top-associated SNP of the gene RP11-707O23.5 in Cerebellar Hemisphere eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for RP11-707O23.5 in Cerebellar Hemisphere eQTL omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 1.57e-16 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-707O23.5" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%cerebellar hemisphere eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1194213', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'RP11-707O23.5', 'p_SMR_multi': 1.567507e-16, 'p_HEIDI': 8.139251000000001e-17, 'Omic_tissue': 'Cerebellar Hemisphere', 'Omic_type': 'Cerebellar Hemisphere eQTL', 'func_sig': 'association meets significance threshold bu... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.187 | Q67 | What is the top-associated SNP of the gene KANSL1-AS1 in Caudate Basal Ganglia eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for KANSL1-AS1 in Caudate Basal Ganglia eQTL omic data for PSP is rs169201, which has a multi-SNP SMR p-value of 2.24e-20 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1-AS1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%caudate basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1283703', 'topRSID': 'rs169201', 'Disease': 'PSP', 'Gene': 'KANSL1-AS1', 'p_SMR_multi': 2.238614e-20, 'p_HEIDI': 2.135793e-09, 'Omic_tissue': 'Caudate Basal Ganglia', 'Omic_type': 'Caudate Basal Ganglia eQTL', 'func_sig': 'association meets significance threshold but shows signs... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.950 | Q67 | What is the top-associated SNP of the gene KLHL7-AS1 in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for KLHL7-AS1 in Whole Blood mQTL omic data for PD is rs1005786, which has a multi-SNP SMR p-value of 1.69e-07 and a HEIDI of 0.05, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KLHL7-AS1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1025673', 'topRSID': 'rs1005786', 'Disease': 'PD', 'Gene': 'KLHL7-AS1', 'p_SMR_multi': 1.686351e-07, 'p_HEIDI': 0.04661481, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_1025670', '... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.247 | Q67 | What is the top-associated SNP of the gene CR1 in Caudate Basal Ganglia eQTL omic data for AD and is it functionally significant? | The top-associated SNP for CR1 in Caudate Basal Ganglia eQTL omic data for AD is rs2093760, which has a multi-SNP SMR p-value of 3.25e-08 and a HEIDI of 0.53, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CR1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%caudate basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1265685', 'topRSID': 'rs2093760', 'Disease': 'AD', 'Gene': 'CR1', 'p_SMR_multi': 3.250883e-08, 'p_HEIDI': 0.5329306, 'Omic_tissue': 'Caudate Basal Ganglia', 'Omic_type': 'Caudate Basal Ganglia eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1100 | Q67 | What is the top-associated SNP of the gene CSDC2 in Cortex eQTL metaBrain omic data for LBD and is it functionally significant? | There are no SNPs within the gene CSDC2 in Cortex eQTL metaBrain omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CSDC2" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%cortex eqtl metabrain%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1133759', 'topRSID': 'rs12484722', 'Disease': 'LBD', 'Gene': 'CSDC2', 'p_SMR_multi': 0.5147756, 'p_HEIDI': 0.02230238, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL metaBrain', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1018 | Q67 | What is the top-associated SNP of the gene DENND2D in Liver eQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene DENND2D in Liver eQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "DENND2D" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%liver eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1467272', 'topRSID': 'rs629608', 'Disease': 'ALS', 'Gene': 'DENND2D', 'p_SMR_multi': 0.261286, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Liver', 'Omic_type': 'Liver eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.590 | Q67 | What is the top-associated SNP of the gene LRRC37A in Cortex eQTL metaBrain omic data for PD and is it functionally significant? | The top-associated SNP for LRRC37A in Cortex eQTL metaBrain omic data for PD is rs2696466, which has a multi-SNP SMR p-value of 1.76e-14 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cortex eqtl metabrain%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1147257', 'topRSID': 'rs2696466', 'Disease': 'PD', 'Gene': 'LRRC37A', 'p_SMR_multi': 1.755785e-14, 'p_HEIDI': 3.958793e-11, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL metaBrain', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Di... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1629 | Q67 | What is the top-associated SNP of the gene NSFP1 in Caudate Basal Ganglia eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for NSFP1 in Caudate Basal Ganglia eQTL omic data for PSP is rs4792831, which has a multi-SNP SMR p-value of 5.32e-11 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "NSFP1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%caudate basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1283709', 'topRSID': 'rs4792831', 'Disease': 'PSP', 'Gene': 'NSFP1', 'p_SMR_multi': 5.322685e-11, 'p_HEIDI': 1.055477e-07, 'Omic_tissue': 'Caudate Basal Ganglia', 'Omic_type': 'Caudate Basal Ganglia eQTL', 'func_sig': 'association meets significance threshold but shows signs of ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.535 | Q67 | What is the top-associated SNP of the gene RPS26P8 in Tibial Nerve eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for RPS26P8 in Tibial Nerve eQTL omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 8.37e-21 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RPS26P8" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%tibial nerve eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1336287', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'RPS26P8', 'p_SMR_multi': 8.372689e-21, 'p_HEIDI': 1.398096e-18, 'Omic_tissue': 'Tibial Nerve', 'Omic_type': 'Tibial Nerve eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.899 | Q67 | What is the top-associated SNP of the gene CD2AP in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for CD2AP in Whole Brain meta-analysis mQTL omic data for AD is rs1004173, which has a multi-SNP SMR p-value of 8.80e-08 and a HEIDI of 0.06, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CD2AP" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_67374', 'topRSID': 'rs7738044', 'Disease': 'AD', 'Gene': 'CD2AP', 'p_SMR_multi': 6.498931e-08, 'p_HEIDI': 0.1048021, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_6737... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1483 | Q67 | What is the top-associated SNP of the gene EPHX2 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for EPHX2 in Whole Blood mQTL omic data for AD is rs36081056, which has a multi-SNP SMR p-value of 1.66e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "EPHX2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_615760', 'topRSID': 'rs36081056', 'Disease': 'AD', 'Gene': 'EPHX2', 'p_SMR_multi': 1.65609e-08, 'p_HEIDI': 4.983638e-05, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1109 | Q67 | What is the top-associated SNP of the gene ARHGAP27 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for ARHGAP27 in Whole Blood mQTL omic data for AD is rs78026984, which has a multi-SNP SMR p-value of 2.25e-06 and a HEIDI of 0.06, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARHGAP27" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_591157', 'topRSID': 'rs35489312', 'Disease': 'AD', 'Gene': 'ARHGAP27', 'p_SMR_multi': 5.523958e-07, 'p_HEIDI': 0.01412357, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_591156', 'to... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.421 | Q67 | What is the top-associated SNP of the gene C6orf58 in Whole Brain meta-analysis mQTL omic data for LBD and is it functionally significant? | There are no SNPs within the gene C6orf58 in Whole Brain meta-analysis mQTL omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "C6orf58" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_350266', 'topRSID': 'rs4897220', 'Disease': 'LBD', 'Gene': 'C6orf58', 'p_SMR_multi': 0.952257, 'p_HEIDI': 0.9275162, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.277 | Q67 | What is the top-associated SNP of the gene PSORS1C1 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for PSORS1C1 in Whole Blood mQTL omic data for AD is rs1042148, which has a multi-SNP SMR p-value of 2.35e-06 and a HEIDI of 0.03, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PSORS1C1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_620729', 'topRSID': 'rs9501055', 'Disease': 'AD', 'Gene': 'PSORS1C1', 'p_SMR_multi': 5.485384e-08, 'p_HEIDI': 0.004858996, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dis... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1174 | Q67 | What is the top-associated SNP of the gene RHOU in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | There are no SNPs within the gene RHOU in Whole Brain meta-analysis mQTL omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RHOU" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_417825', 'topRSID': 'rs2295256', 'Disease': 'PD', 'Gene': 'RHOU', 'p_SMR_multi': 0.4116305, 'p_HEIDI': 0.9247686, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1487 | Q67 | What is the top-associated SNP of the gene ZCWPW1 in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for ZCWPW1 in Whole Blood eQTL eQTLgen omic data for AD is rs35111986, which has a multi-SNP SMR p-value of 1.45e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ZCWPW1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1495808', 'topRSID': 'rs35111986', 'Disease': 'AD', 'Gene': 'ZCWPW1', 'p_SMR_multi': 1.453775e-07, 'p_HEIDI': 5.242166e-05, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Li... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1456 | Q67 | What is the top-associated SNP of the gene RP11-347C12.2 in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for RP11-347C12.2 in Whole Blood eQTL eQTLgen omic data for AD is rs8050176, which has a multi-SNP SMR p-value of 1.66e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-347C12.2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1501450', 'topRSID': 'rs8050176', 'Disease': 'AD', 'Gene': 'RP11-347C12.2', 'p_SMR_multi': 1.664191e-07, 'p_HEIDI': 0.0003516688, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linka... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.253 | Q67 | What is the top-associated SNP of the gene PM20D1 in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for PM20D1 in Whole Blood mQTL omic data for PD is rs823080, which has a multi-SNP SMR p-value of 7.08e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PM20D1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_944692', 'topRSID': 'rs823080', 'Disease': 'PD', 'Gene': 'PM20D1', 'p_SMR_multi': 7.078994e-07, 'p_HEIDI': 1.577211e-06, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.419 | Q67 | What is the top-associated SNP of the gene FAM181B in Whole Blood mQTL omic data for PD and is it functionally significant? | There are no SNPs within the gene FAM181B in Whole Blood mQTL omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "FAM181B" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_959664', 'topRSID': 'rs17144161', 'Disease': 'PD', 'Gene': 'FAM181B', 'p_SMR_multi': 0.7229133, 'p_HEIDI': 0.6321765, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_959665', 'top... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1590 | Q67 | What is the top-associated SNP of the gene D2HGDH in Hypothalamus eQTL omic data for PD and is it functionally significant? | There are no SNPs within the gene D2HGDH in Hypothalamus eQTL omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "D2HGDH" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%hypothalamus eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1461484', 'topRSID': 'rs7582582', 'Disease': 'PD', 'Gene': 'D2HGDH', 'p_SMR_multi': 0.9523597, 'p_HEIDI': 0.8970851, 'Omic_tissue': 'Hypothalamus', 'Omic_type': 'Hypothalamus eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1895 | Q67 | What is the top-associated SNP of the gene RP11-259G18.3 in Putamen Basal Ganglia eQTL omic data for PD and is it functionally significant? | The top-associated SNP for RP11-259G18.3 in Putamen Basal Ganglia eQTL omic data for PD is rs62061822, which has a multi-SNP SMR p-value of 9.55e-12 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.3" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%putamen basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1594926', 'topRSID': 'rs62061822', 'Disease': 'PD', 'Gene': 'RP11-259G18.3', 'p_SMR_multi': 9.554985e-12, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Putamen Basal Ganglia', 'Omic_type': 'Putamen Basal Ganglia eQTL', 'func_sig': 'association meets significance threshold but shows signs ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.582 | Q67 | What is the top-associated SNP of the gene KANSL1-AS1 in Putamen Basal Ganglia eQTL omic data for AD and is it functionally significant? | The top-associated SNP for KANSL1-AS1 in Putamen Basal Ganglia eQTL omic data for AD is rs55974014, which has a multi-SNP SMR p-value of 2.78e-06 and a HEIDI of 0.88, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1-AS1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%putamen basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1584311', 'topRSID': 'rs55974014', 'Disease': 'AD', 'Gene': 'KANSL1-AS1', 'p_SMR_multi': 2.780259e-06, 'p_HEIDI': 0.8793121, 'Omic_tissue': 'Putamen Basal Ganglia', 'Omic_type': 'Putamen Basal Ganglia eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.314 | Q67 | What is the top-associated SNP of the gene TEC in Whole Blood mQTL omic data for PD and is it functionally significant? | There are no SNPs within the gene TEC in Whole Blood mQTL omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TEC" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_998078', 'topRSID': 'rs2661533', 'Disease': 'PD', 'Gene': 'TEC', 'p_SMR_multi': 0.3914678, 'p_HEIDI': 0.7989208, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_998079', 'topRSID'... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1962 | Q67 | What is the top-associated SNP of the gene VASP in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for VASP in Whole Blood eQTL eQTLgen omic data for AD is rs7252959, which has a multi-SNP SMR p-value of 4.47e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "VASP" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1503927', 'topRSID': 'rs7252959', 'Disease': 'AD', 'Gene': 'VASP', 'p_SMR_multi': 4.468401e-07, 'p_HEIDI': 0.001260265, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkag... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.387 | Q67 | What is the top-associated SNP of the gene MAPT-AS1 in Nucleus Accumbens Basal Ganglia omic data for PD and is it functionally significant? | The top-associated SNP for MAPT-AS1 in Nucleus Accumbens Basal Ganglia omic data for PD is rs62055937, which has a multi-SNP SMR p-value of 5.14e-10 and a HEIDI of 0.26, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT-AS1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%nucleus accumbens basal ganglia%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1730063', 'topRSID': 'rs62055937', 'Disease': 'PD', 'Gene': 'MAPT-AS1', 'p_SMR_multi': 5.137261e-10, 'p_HEIDI': 0.2586129, 'Omic_tissue': 'Nucleus Accumbens Basal', 'Omic_type': 'Nucleus Accumbens Basal Ganglia', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.541 | Q67 | What is the top-associated SNP of the gene GPNMB in Frontal Cortex BA9 eQTL omic data for PD and is it functionally significant? | The top-associated SNP for GPNMB in Frontal Cortex BA9 eQTL omic data for PD is rs199357, which has a multi-SNP SMR p-value of 1.20e-06 and a HEIDI of 0.2, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "GPNMB" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%frontal cortex ba9 eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1167543', 'topRSID': 'rs199357', 'Disease': 'PD', 'Gene': 'GPNMB', 'p_SMR_multi': 1.201065e-06, 'p_HEIDI': 0.20057, 'Omic_tissue': 'Frontal Cortex', 'Omic_type': 'Frontal Cortex BA9 eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.431 | Q67 | What is the top-associated SNP of the gene ARHGAP27 in Caudate Basal Ganglia eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for ARHGAP27 in Caudate Basal Ganglia eQTL omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 4.80e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARHGAP27" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%caudate basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1283695', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'ARHGAP27', 'p_SMR_multi': 4.799834e-08, 'p_HEIDI': 4.737999e-06, 'Omic_tissue': 'Caudate Basal Ganglia', 'Omic_type': 'Caudate Basal Ganglia eQTL', 'func_sig': 'association meets significance threshold but shows signs ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.657 | Q67 | What is the top-associated SNP of the gene WNT3 in Whole Blood eQTL eQTLgen omic data for PSP and is it functionally significant? | The top-associated SNP for WNT3 in Whole Blood eQTL eQTLgen omic data for PSP is rs2074404, which has a multi-SNP SMR p-value of 6.75e-20 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "WNT3" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1579433', 'topRSID': 'rs2074404', 'Disease': 'PSP', 'Gene': 'WNT3', 'p_SMR_multi': 6.747848e-20, 'p_HEIDI': 0.000130815, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linka... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1642 | Q67 | What is the top-associated SNP of the gene LRRC37A in Basal Ganglia eQTL omic data for PD and is it functionally significant? | The top-associated SNP for LRRC37A in Basal Ganglia eQTL omic data for PD is rs2696466, which has a multi-SNP SMR p-value of 1.31e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_27183', 'topRSID': 'rs2696466', 'Disease': 'PD', 'Gene': 'LRRC37A', 'p_SMR_multi': 1.310623e-09, 'p_HEIDI': 6.072306e-05, 'Omic_tissue': 'Basal Ganglia', 'Omic_type': 'Basal Ganglia eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1318 | Q67 | What is the top-associated SNP of the gene CRHR1 in Whole Blood mQTL omic data for PSP and is it functionally significant? | The top-associated SNP for CRHR1 in Whole Blood mQTL omic data for PSP is rs169201, which has a multi-SNP SMR p-value of 1.41e-10 and a HEIDI of 0.35, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CRHR1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1041722', 'topRSID': 'rs169201', 'Disease': 'PSP', 'Gene': 'CRHR1', 'p_SMR_multi': 2.917855e-34, 'p_HEIDI': 1.464444e-09, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dise... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1358 | Q67 | What is the top-associated SNP of the gene NUPL2 in Cortex eQTL GTEx omic data for PD and is it functionally significant? | The top-associated SNP for NUPL2 in Cortex eQTL GTEx omic data for PD is rs1881201, which has a multi-SNP SMR p-value of 8.47e-07 and a HEIDI of 0.52, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "NUPL2" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cortex eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1260546', 'topRSID': 'rs1881201', 'Disease': 'PD', 'Gene': 'NUPL2', 'p_SMR_multi': 8.474918e-07, 'p_HEIDI': 0.5226387, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL GTEx', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.414 | Q67 | What is the top-associated SNP of the gene C6orf10 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for C6orf10 in Whole Blood mQTL omic data for AD is rs679242, which has a multi-SNP SMR p-value of 5.69e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "C6orf10" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_621662', 'topRSID': 'rs35265698', 'Disease': 'AD', 'Gene': 'C6orf10', 'p_SMR_multi': 2.929935e-08, 'p_HEIDI': 2.344082e-06, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Di... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1615 | Q67 | What is the top-associated SNP of the gene LRRC37A2 in Anterior Cingulate Cortex BA24 eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for LRRC37A2 in Anterior Cingulate Cortex BA24 eQTL omic data for PSP is rs8070723, which has a multi-SNP SMR p-value of 6.47e-17 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A2" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%anterior cingulate cortex ba24 eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1489544', 'topRSID': 'rs8070723', 'Disease': 'PSP', 'Gene': 'LRRC37A2', 'p_SMR_multi': 6.474394000000001e-17, 'p_HEIDI': 9.961509e-19, 'Omic_tissue': 'Anterior Cingulate Cortex BA24', 'Omic_type': 'Anterior Cingulate Cortex BA24 eQTL', 'func_sig': 'association meets significance... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.687 | Q67 | What is the top-associated SNP of the gene STX4 in Skeletal Muscle eQTL omic data for PD and is it functionally significant? | The top-associated SNP for STX4 in Skeletal Muscle eQTL omic data for PD is rs732173, which has a multi-SNP SMR p-value of 2.89e-06 and a HEIDI of 0.07, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "STX4" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%skeletal muscle eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1370180', 'topRSID': 'rs732173', 'Disease': 'PD', 'Gene': 'STX4', 'p_SMR_multi': 2.892341e-06, 'p_HEIDI': 0.06646784, 'Omic_tissue': 'Skeletal Muscle', 'Omic_type': 'Skeletal Muscle eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.621 | Q67 | What is the top-associated SNP of the gene LRRC37A4P in Whole Brain eQTL omic data for AD and is it functionally significant? | The top-associated SNP for LRRC37A4P in Whole Brain eQTL omic data for AD is rs112431991, which has a multi-SNP SMR p-value of 1.38e-07 and a HEIDI of 0.04, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A4P" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1610857', 'topRSID': 'rs112431991', 'Disease': 'AD', 'Gene': 'LRRC37A4P', 'p_SMR_multi': 1.378159e-07, 'p_HEIDI': 0.03802183, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.923 | Q67 | What is the top-associated SNP of the gene APOC4 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for APOC4 in Whole Brain meta-analysis mQTL omic data for AD is rs112391061, which has a multi-SNP SMR p-value of 1.45e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "APOC4" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_122468', 'topRSID': 'rs11878597', 'Disease': 'AD', 'Gene': 'APOC4', 'p_SMR_multi': 1.942575e-13, 'p_HEIDI': 5.901231e-09, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1199 | Q67 | What is the top-associated SNP of the gene PGLYRP2 in Whole Blood eQTL eQTLgen omic data for LBD and is it functionally significant? | There are no SNPs within the gene PGLYRP2 in Whole Blood eQTL eQTLgen omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PGLYRP2" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1550168', 'topRSID': 'rs11882108', 'Disease': 'LBD', 'Gene': 'PGLYRP2', 'p_SMR_multi': 0.4320717, 'p_HEIDI': 0.8444771, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.839 | Q67 | What is the top-associated SNP of the gene DOC2A in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for DOC2A in Whole Brain meta-analysis mQTL omic data for AD is rs12325400, which has a multi-SNP SMR p-value of 9.99e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "DOC2A" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_109454', 'topRSID': 'rs10871451', 'Disease': 'AD', 'Gene': 'DOC2A', 'p_SMR_multi': 7.531563e-08, 'p_HEIDI': 0.000390338, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1771 | Q67 | What is the top-associated SNP of the gene MAPT-AS1 in Prefrontal Cortex eQTL omic data for PD and is it functionally significant? | The top-associated SNP for MAPT-AS1 in Prefrontal Cortex eQTL omic data for PD is rs575074983, which has a multi-SNP SMR p-value of 4.05e-12 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT-AS1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%prefrontal cortex eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1242274', 'topRSID': 'rs575074983', 'Disease': 'PD', 'Gene': 'MAPT-AS1', 'p_SMR_multi': 4.049628e-12, 'p_HEIDI': 5.072383e-05, 'Omic_tissue': 'Prefrontal Cortex', 'Omic_type': 'Prefrontal Cortex eQTL', 'func_sig': 'association meets significance threshold but shows signs of link... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.953 | Q67 | What is the top-associated SNP of the gene TNNT1 in Whole Brain eQTL omic data for PD and is it functionally significant? | There are no SNPs within the gene TNNT1 in Whole Brain eQTL omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TNNT1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1641023', 'topRSID': 'rs891186', 'Disease': 'PD', 'Gene': 'TNNT1', 'p_SMR_multi': 0.06884702, 'p_HEIDI': 0.5352333, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.185 | Q67 | What is the top-associated SNP of the gene MAPT in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for MAPT in Whole Blood mQTL omic data for PD is rs62063271, which has a multi-SNP SMR p-value of 2.11e-14 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_948891', 'topRSID': 'rs62063271', 'Disease': 'PD', 'Gene': 'MAPT', 'p_SMR_multi': 6.382411e-15, 'p_HEIDI': 2.368028e-06, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1072 | Q67 | What is the top-associated SNP of the gene ARL17A in Cerebellum eQTL omic data for PD and is it functionally significant? | The top-associated SNP for ARL17A in Cerebellum eQTL omic data for PD is rs4471723, which has a multi-SNP SMR p-value of 1.34e-13 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARL17A" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_19651', 'topRSID': 'rs4471723', 'Disease': 'PD', 'Gene': 'ARL17A', 'p_SMR_multi': 1.337634e-13, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequilibri... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.711 | Q67 | What is the top-associated SNP of the gene INO80E in Cerebellum eQTL omic data for AD and is it functionally significant? | The top-associated SNP for INO80E in Cerebellum eQTL omic data for AD is rs9932196, which has a multi-SNP SMR p-value of 8.81e-07 and a HEIDI of 0.2, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "INO80E" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_2876', 'topRSID': 'rs9932196', 'Disease': 'AD', 'Gene': 'INO80E', 'p_SMR_multi': 8.807658e-07, 'p_HEIDI': 0.1988687, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_1689746', 'topRSID':... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.173 | Q67 | What is the top-associated SNP of the gene MEFV in Whole Blood mQTL omic data for AD and is it functionally significant? | There are no SNPs within the gene MEFV in Whole Blood mQTL omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MEFV" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_576592', 'topRSID': 'rs12325636', 'Disease': 'AD', 'Gene': 'MEFV', 'p_SMR_multi': 0.2966068, 'p_HEIDI': 0.1072575, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_576593', 'topRSI... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.296 | Q67 | What is the top-associated SNP of the gene LRRC37A in Cerebellar Hemisphere eQTL omic data for AD and is it functionally significant? | The top-associated SNP for LRRC37A in Cerebellar Hemisphere eQTL omic data for AD is rs4510068, which has a multi-SNP SMR p-value of 2.24e-06 and a HEIDI of 0.48, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%cerebellar hemisphere eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1174603', 'topRSID': 'rs4510068', 'Disease': 'AD', 'Gene': 'LRRC37A', 'p_SMR_multi': 2.236244e-06, 'p_HEIDI': 0.4781917, 'Omic_tissue': 'Cerebellar Hemisphere', 'Omic_type': 'Cerebellar Hemisphere eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.554 | Q67 | What is the top-associated SNP of the gene NSFP1 in Frontal Cortex BA9 eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for NSFP1 in Frontal Cortex BA9 eQTL omic data for PSP is rs4792831, which has a multi-SNP SMR p-value of 1.11e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "NSFP1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%frontal cortex ba9 eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1170878', 'topRSID': 'rs4792831', 'Disease': 'PSP', 'Gene': 'NSFP1', 'p_SMR_multi': 1.110217e-09, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Frontal Cortex', 'Omic_type': 'Frontal Cortex BA9 eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkag... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.763 | Q67 | What is the top-associated SNP of the gene MMRN1 in Whole Blood eQTL eQTLgen omic data for PD and is it functionally significant? | The top-associated SNP for MMRN1 in Whole Blood eQTL eQTLgen omic data for PD is rs1372525, which has a multi-SNP SMR p-value of 1.83e-15 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MMRN1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1555944', 'topRSID': 'rs1372525', 'Disease': 'PD', 'Gene': 'MMRN1', 'p_SMR_multi': 1.827247e-15, 'p_HEIDI': 2.599436e-20, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Link... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.304 | Q67 | What is the top-associated SNP of the gene RP11-707O23.5 in Tibial Nerve eQTL omic data for AD and is it functionally significant? | The top-associated SNP for RP11-707O23.5 in Tibial Nerve eQTL omic data for AD is rs55974014, which has a multi-SNP SMR p-value of 2.54e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-707O23.5" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%tibial nerve eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1291755', 'topRSID': 'rs55974014', 'Disease': 'AD', 'Gene': 'RP11-707O23.5', 'p_SMR_multi': 2.544718e-06, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Tibial Nerve', 'Omic_type': 'Tibial Nerve eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkag... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1878 | Q67 | What is the top-associated SNP of the gene GULOP in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for GULOP in Whole Blood mQTL omic data for AD is rs7465418, which has a multi-SNP SMR p-value of 4.14e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "GULOP" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_615765', 'topRSID': 'rs6558008', 'Disease': 'AD', 'Gene': 'GULOP', 'p_SMR_multi': 1.318045e-11, 'p_HEIDI': 0.0001131265, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1093 | Q67 | What is the top-associated SNP of the gene RAB7L1 in Whole Blood eQTL eQTLgen omic data for PD and is it functionally significant? | The top-associated SNP for RAB7L1 in Whole Blood eQTL eQTLgen omic data for PD is rs7522056, which has a multi-SNP SMR p-value of 7.29e-07 and a HEIDI of 0.06, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RAB7L1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1553467', 'topRSID': 'rs7522056', 'Disease': 'PD', 'Gene': 'RAB7L1', 'p_SMR_multi': 7.294008e-07, 'p_HEIDI': 0.05855961, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1747 | Q67 | What is the top-associated SNP of the gene CHRNA2 in Cerebellum eQTL omic data for AD and is it functionally significant? | The top-associated SNP for CHRNA2 in Cerebellum eQTL omic data for AD is rs2472554, which has a multi-SNP SMR p-value of 1.13e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CHRNA2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_3683', 'topRSID': 'rs2472554', 'Disease': 'AD', 'Gene': 'CHRNA2', 'p_SMR_multi': 1.132264e-07, 'p_HEIDI': 0.001579673, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequili... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1652 | Q67 | What is the top-associated SNP of the gene LRRC37A17P in Prefrontal Cortex eQTL omic data for PD and is it functionally significant? | The top-associated SNP for LRRC37A17P in Prefrontal Cortex eQTL omic data for PD is rs4630591, which has a multi-SNP SMR p-value of 2.43e-06 and a HEIDI of 0.27, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A17P" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%prefrontal cortex eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1242291', 'topRSID': 'rs4630591', 'Disease': 'PD', 'Gene': 'LRRC37A17P', 'p_SMR_multi': 2.430773e-06, 'p_HEIDI': 0.2662457, 'Omic_tissue': 'Prefrontal Cortex', 'Omic_type': 'Prefrontal Cortex eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.914 | Q67 | What is the top-associated SNP of the gene CRHR1-IT1 in Skeletal Muscle eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for CRHR1-IT1 in Skeletal Muscle eQTL omic data for PSP is rs12373139, which has a multi-SNP SMR p-value of 4.50e-32 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CRHR1-IT1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%skeletal muscle eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1375927', 'topRSID': 'rs12373139', 'Disease': 'PSP', 'Gene': 'CRHR1-IT1', 'p_SMR_multi': 4.501672e-32, 'p_HEIDI': 1.9406400000000003e-24, 'Omic_tissue': 'Skeletal Muscle', 'Omic_type': 'Skeletal Muscle eQTL', 'func_sig': 'association meets significance threshold but shows signs ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1932 | Q67 | What is the top-associated SNP of the gene RAB29 in Cortex eQTL metaBrain omic data for PD and is it functionally significant? | The top-associated SNP for RAB29 in Cortex eQTL metaBrain omic data for PD is rs823118, which has a multi-SNP SMR p-value of 1.91e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RAB29" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cortex eqtl metabrain%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1142765', 'topRSID': 'rs823118', 'Disease': 'PD', 'Gene': 'RAB29', 'p_SMR_multi': 1.914143e-06, 'p_HEIDI': 0.004581236, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL metaBrain', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.275 | Q67 | What is the top-associated SNP of the gene PITPNM3 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | There are no SNPs within the gene PITPNM3 in Whole Brain meta-analysis mQTL omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PITPNM3" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_489068', 'topRSID': 'rs356036', 'Disease': 'PD', 'Gene': 'PITPNM3', 'p_SMR_multi': 0.03429788, 'p_HEIDI': 0.08791738, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1147 | Q67 | What is the top-associated SNP of the gene ELOVL7 in Tibial Nerve eQTL omic data for PD and is it functionally significant? | The top-associated SNP for ELOVL7 in Tibial Nerve eQTL omic data for PD is rs4700390, which has a multi-SNP SMR p-value of 7.88e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ELOVL7" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%tibial nerve eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1323825', 'topRSID': 'rs4700390', 'Disease': 'PD', 'Gene': 'ELOVL7', 'p_SMR_multi': 7.877688e-07, 'p_HEIDI': 0.0004349221, 'Omic_tissue': 'Tibial Nerve', 'Omic_type': 'Tibial Nerve eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage D... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1589 | Q67 | What is the top-associated SNP of the gene HIP1R in Cerebellum eQTL omic data for PD and is it functionally significant? | The top-associated SNP for HIP1R in Cerebellum eQTL omic data for PD is rs10847864, which has a multi-SNP SMR p-value of 2.07e-06 and a HEIDI of 0.06, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "HIP1R" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_20980', 'topRSID': 'rs10847864', 'Disease': 'PD', 'Gene': 'HIP1R', 'p_SMR_multi': 1.644024e-07, 'p_HEIDI': 0.6629918, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_1709448', 'topRSID'... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.700 | Q67 | What is the top-associated SNP of the gene RP11-259G18.1 in Frontal Cortex BA9 eQTL omic data for PD and is it functionally significant? | The top-associated SNP for RP11-259G18.1 in Frontal Cortex BA9 eQTL omic data for PD is rs62063281, which has a multi-SNP SMR p-value of 1.74e-08 and a HEIDI of 0.04, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%frontal cortex ba9 eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1168838', 'topRSID': 'rs62063281', 'Disease': 'PD', 'Gene': 'RP11-259G18.1', 'p_SMR_multi': 1.741126e-08, 'p_HEIDI': 0.04436433, 'Omic_tissue': 'Frontal Cortex', 'Omic_type': 'Frontal Cortex BA9 eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1765 | Q67 | What is the top-associated SNP of the gene GPC2 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for GPC2 in Whole Brain meta-analysis mQTL omic data for AD is rs6465765, which has a multi-SNP SMR p-value of 1.85e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "GPC2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_74045', 'topRSID': 'rs866500', 'Disease': 'AD', 'Gene': 'GPC2', 'p_SMR_multi': 6.77721e-09, 'p_HEIDI': 5.570468e-05, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Lin... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.488 | Q67 | What is the top-associated SNP of the gene MAPT-AS1 in Whole Brain meta-analysis mQTL omic data for PSP and is it functionally significant? | The top-associated SNP for MAPT-AS1 in Whole Brain meta-analysis mQTL omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 7.28e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT-AS1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_560854', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'MAPT-AS1', 'p_SMR_multi': 1.544458e-18, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.428 | Q67 | What is the top-associated SNP of the gene CR1 in Prefrontal Cortex eQTL omic data for AD and is it functionally significant? | The top-associated SNP for CR1 in Prefrontal Cortex eQTL omic data for AD is rs679515, which has a multi-SNP SMR p-value of 1.08e-12 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CR1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%prefrontal cortex eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1195476', 'topRSID': 'rs679515', 'Disease': 'AD', 'Gene': 'CR1', 'p_SMR_multi': 1.077391e-12, 'p_HEIDI': 0.002839407, 'Omic_tissue': 'Prefrontal Cortex', 'Omic_type': 'Prefrontal Cortex eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Link... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.377 | Q67 | What is the top-associated SNP of the gene GAK in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for GAK in Whole Brain meta-analysis mQTL omic data for PD is rs11248057, which has a multi-SNP SMR p-value of 9.57e-09 and a HEIDI of 0.01, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "GAK" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_429832', 'topRSID': 'rs11248057', 'Disease': 'PD', 'Gene': 'GAK', 'p_SMR_multi': 1.488653e-10, 'p_HEIDI': 1.165356e-06, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1008 | Q67 | What is the top-associated SNP of the gene DND1P1 in Nucleus Accumbens Basal Ganglia omic data for PSP and is it functionally significant? | The top-associated SNP for DND1P1 in Nucleus Accumbens Basal Ganglia omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 1.98e-15 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "DND1P1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%nucleus accumbens basal ganglia%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1732391', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'DND1P1', 'p_SMR_multi': 1.984919e-15, 'p_HEIDI': 1.222775e-14, 'Omic_tissue': 'Nucleus Accumbens Basal', 'Omic_type': 'Nucleus Accumbens Basal Ganglia', 'func_sig': 'association meets significance threshold but shows s... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1003 | Q67 | What is the top-associated SNP of the gene TMEM175 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for TMEM175 in Whole Brain meta-analysis mQTL omic data for PD is rs2290403, which has a multi-SNP SMR p-value of 9.38e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TMEM175" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_429841', 'topRSID': 'rs10008187', 'Disease': 'PD', 'Gene': 'TMEM175', 'p_SMR_multi': 4.414637e-10, 'p_HEIDI': 0.4333231, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1940 | Q67 | What is the top-associated SNP of the gene RP11-798G7.8 in Whole Blood eQTL GTEx omic data for PSP and is it functionally significant? | The top-associated SNP for RP11-798G7.8 in Whole Blood eQTL GTEx omic data for PSP is rs7220988, which has a multi-SNP SMR p-value of 9.97e-11 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-798G7.8" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1684929', 'topRSID': 'rs7220988', 'Disease': 'PSP', 'Gene': 'RP11-798G7.8', 'p_SMR_multi': 9.967724e-11, 'p_HEIDI': 8.274962e-09, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL GTEx', 'func_sig': 'association meets significance threshold but shows signs of linkage/... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.714 | Q67 | What is the top-associated SNP of the gene IDUA in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for IDUA in Whole Brain meta-analysis mQTL omic data for PD is rs1051613, which has a multi-SNP SMR p-value of 4.55e-13 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "IDUA" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_429873', 'topRSID': 'rs1051613', 'Disease': 'PD', 'Gene': 'IDUA', 'p_SMR_multi': 4.554749e-13, 'p_HEIDI': 2.213052e-05, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1335 | Q67 | What is the top-associated SNP of the gene TCAP in Whole Blood mQTL omic data for FTD and is it functionally significant? | There are no SNPs within the gene TCAP in Whole Blood mQTL omic data that are significantly associated with FTD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TCAP" AND Disease = "FTD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_832605', 'topRSID': 'rs9907501', 'Disease': 'FTD', 'Gene': 'TCAP', 'p_SMR_multi': 0.4116744, 'p_HEIDI': 0.9465263, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_832610', 'topRSI... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1156 | Q67 | What is the top-associated SNP of the gene CLPTM1 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for CLPTM1 in Whole Brain meta-analysis mQTL omic data for AD is rs112704499, which has a multi-SNP SMR p-value of 2.72e-11 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CLPTM1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_122472', 'topRSID': 'rs112704499', 'Disease': 'AD', 'Gene': 'CLPTM1', 'p_SMR_multi': 2.721346e-11, 'p_HEIDI': 2.477034e-09, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linka... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.338 | Q67 | What is the top-associated SNP of the gene FANCA in Whole Brain meta-analysis mQTL omic data for FTD and is it functionally significant? | There are no SNPs within the gene FANCA in Whole Brain meta-analysis mQTL omic data that are significantly associated with FTD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "FANCA" AND Disease = "FTD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_300204', 'topRSID': 'rs17233651', 'Disease': 'FTD', 'Gene': 'FANCA', 'p_SMR_multi': 0.0842764, 'p_HEIDI': 0.8318458, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1343 | Q67 | What is the top-associated SNP of the gene TMEM175 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for TMEM175 in Whole Brain meta-analysis mQTL omic data for PD is rs10008187, which has a multi-SNP SMR p-value of 1.40e-09 and a HEIDI of 0.22, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TMEM175" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_429841', 'topRSID': 'rs10008187', 'Disease': 'PD', 'Gene': 'TMEM175', 'p_SMR_multi': 4.414637e-10, 'p_HEIDI': 0.4333231, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1593 | Q67 | What is the top-associated SNP of the gene KANSL1 in Whole Blood mQTL omic data for PSP and is it functionally significant? | The top-associated SNP for KANSL1 in Whole Blood mQTL omic data for PSP is rs415430, which has a multi-SNP SMR p-value of 1.08e-10 and a HEIDI of 0.02, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1041761', 'topRSID': 'rs169201', 'Disease': 'PSP', 'Gene': 'KANSL1', 'p_SMR_multi': 3.489683e-40, 'p_HEIDI': 3.497522e-13, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dis... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1993 | Q67 | What is the top-associated SNP of the gene LRRC37A2 in Skeletal Muscle eQTL omic data for PD and is it functionally significant? | The top-associated SNP for LRRC37A2 in Skeletal Muscle eQTL omic data for PD is rs3874943, which has a multi-SNP SMR p-value of 8.93e-13 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A2" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%skeletal muscle eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1370552', 'topRSID': 'rs3874943', 'Disease': 'PD', 'Gene': 'LRRC37A2', 'p_SMR_multi': 8.931825e-13, 'p_HEIDI': 4.194367e-06, 'Omic_tissue': 'Skeletal Muscle', 'Omic_type': 'Skeletal Muscle eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ L... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.598 | Q67 | What is the top-associated SNP of the gene CRHR1 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for CRHR1 in Whole Blood mQTL omic data for AD is rs113790915, which has a multi-SNP SMR p-value of 7.46e-07 and a HEIDI of 0.18, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CRHR1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_591172', 'topRSID': 'rs17689882', 'Disease': 'AD', 'Gene': 'CRHR1', 'p_SMR_multi': 3.894906e-07, 'p_HEIDI': 0.008599073, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.16 | Q67 | What is the top-associated SNP of the gene CDCA7L in Tibial Nerve eQTL omic data for PD and is it functionally significant? | There are no SNPs within the gene CDCA7L in Tibial Nerve eQTL omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CDCA7L" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%tibial nerve eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1324761', 'topRSID': 'rs57191357', 'Disease': 'PD', 'Gene': 'CDCA7L', 'p_SMR_multi': 0.6061562, 'p_HEIDI': 0.7912323, 'Omic_tissue': 'Tibial Nerve', 'Omic_type': 'Tibial Nerve eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1855 | Q67 | What is the top-associated SNP of the gene EGFR in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD and is it functionally significant? | The top-associated SNP for EGFR in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD is rs74504435, which has a multi-SNP SMR p-value of 6.93e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "EGFR" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1392477', 'topRSID': 'rs74504435', 'Disease': 'AD', 'Gene': 'EGFR', 'p_SMR_multi': 6.929527e-07, 'p_HEIDI': 6.639836e-08, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'association meets significance thresh... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1634 | Q67 | What is the top-associated SNP of the gene KANSL1 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for KANSL1 in Whole Brain meta-analysis mQTL omic data for AD is rs12150087, which has a multi-SNP SMR p-value of 1.65e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_115207', 'topRSID': 'rs2696569', 'Disease': 'AD', 'Gene': 'KANSL1', 'p_SMR_multi': 5.266316e-08, 'p_HEIDI': 0.01258408, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_1... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1686 | Q67 | What is the top-associated SNP of the gene NOTCH4 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for NOTCH4 in Whole Blood mQTL omic data for AD is rs34562262, which has a multi-SNP SMR p-value of 1.29e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "NOTCH4" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_621620', 'topRSID': 'rs34562262', 'Disease': 'AD', 'Gene': 'NOTCH4', 'p_SMR_multi': 1.292283e-07, 'p_HEIDI': 0.003108897, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dise... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.600 | Q67 | What is the top-associated SNP of the gene LHFPL2 in Whole Blood mQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene LHFPL2 in Whole Blood mQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LHFPL2" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_732181', 'topRSID': 'rs4235706', 'Disease': 'ALS', 'Gene': 'LHFPL2', 'p_SMR_multi': 0.3319539, 'p_HEIDI': 0.271035, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_732176', 'topRS... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.924 | Q67 | What is the top-associated SNP of the gene MMRN1 in Putamen Basal Ganglia eQTL omic data for PD and is it functionally significant? | The top-associated SNP for MMRN1 in Putamen Basal Ganglia eQTL omic data for PD is rs116370523, which has a multi-SNP SMR p-value of 3.53e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MMRN1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%putamen basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1593387', 'topRSID': 'rs116370523', 'Disease': 'PD', 'Gene': 'MMRN1', 'p_SMR_multi': 3.533898e-08, 'p_HEIDI': 0.0003885268, 'Omic_tissue': 'Putamen Basal Ganglia', 'Omic_type': 'Putamen Basal Ganglia eQTL', 'func_sig': 'association meets significance threshold but shows signs of... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.471 | Q67 | What is the top-associated SNP of the gene CSGALNACT1 in Whole Blood mQTL omic data for LBD and is it functionally significant? | There are no SNPs within the gene CSGALNACT1 in Whole Blood mQTL omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CSGALNACT1" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_917439', 'topRSID': 'rs11204063', 'Disease': 'LBD', 'Gene': 'CSGALNACT1', 'p_SMR_multi': 0.1565818, 'p_HEIDI': 0.8048319, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_917441', ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.202 | Q67 | What is the top-associated SNP of the gene MEPCE in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD and is it functionally significant? | The top-associated SNP for MEPCE in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD is rs6970806, which has a multi-SNP SMR p-value of 2.14e-06 and a HEIDI of 0.09, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MEPCE" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1392631', 'topRSID': 'rs6970806', 'Disease': 'AD', 'Gene': 'MEPCE', 'p_SMR_multi': 2.137433e-06, 'p_HEIDI': 0.09292833, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1206 | Q67 | What is the top-associated SNP of the gene STX1B in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for STX1B in Whole Blood mQTL omic data for PD is rs9796794, which has a multi-SNP SMR p-value of 1.98e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "STX1B" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_974667', 'topRSID': 'rs9796794', 'Disease': 'PD', 'Gene': 'STX1B', 'p_SMR_multi': 1.979272e-07, 'p_HEIDI': 0.003601113, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1056 | Q67 | What is the top-associated SNP of the gene FMNL1 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for PD and is it functionally significant? | The top-associated SNP for FMNL1 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for PD is rs62063276, which has a multi-SNP SMR p-value of 1.99e-11 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "FMNL1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1435910', 'topRSID': 'rs62063276', 'Disease': 'PD', 'Gene': 'FMNL1', 'p_SMR_multi': 1.990946e-11, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'association meets significance threshold ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1195 | Q67 | What is the top-associated SNP of the gene FAM215B in Whole Brain eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for FAM215B in Whole Brain eQTL omic data for PSP is rs11012, which has a multi-SNP SMR p-value of 2.49e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "FAM215B" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole brain eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1646052', 'topRSID': 'rs11012', 'Disease': 'PSP', 'Gene': 'FAM215B', 'p_SMR_multi': 2.487877e-07, 'p_HEIDI': 1.410288e-06, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dis... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1300 | Q67 | What is the top-associated SNP of the gene AC012146.7 in Whole Brain eQTL omic data for AD and is it functionally significant? | The top-associated SNP for AC012146.7 in Whole Brain eQTL omic data for AD is rs73976310, which has a multi-SNP SMR p-value of 3.17e-07 and a HEIDI of 0.24, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "AC012146.7" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1610627', 'topRSID': 'rs73976310', 'Disease': 'AD', 'Gene': 'AC012146.7', 'p_SMR_multi': 3.174282e-07, 'p_HEIDI': 0.2421744, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1276 | Q67 | What is the top-associated SNP of the gene KANSL1 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for KANSL1 in Whole Brain meta-analysis mQTL omic data for PD is rs1966345, which has a multi-SNP SMR p-value of 3.50e-15 and a HEIDI of 0.06, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_491139', 'topRSID': 'rs12150087', 'Disease': 'PD', 'Gene': 'KANSL1', 'p_SMR_multi': 8.107128999999999e-20, 'p_HEIDI': 0.009069932, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs o... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1814 | Q67 | What is the top-associated SNP of the gene SLC25A12 in Tibial Nerve eQTL omic data for LBD and is it functionally significant? | There are no SNPs within the gene SLC25A12 in Tibial Nerve eQTL omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SLC25A12" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%tibial nerve eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1313368', 'topRSID': 'rs7580232', 'Disease': 'LBD', 'Gene': 'SLC25A12', 'p_SMR_multi': 0.8722969, 'p_HEIDI': 0.5630811, 'Omic_tissue': 'Tibial Nerve', 'Omic_type': 'Tibial Nerve eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1402 | Q67 | What is the top-associated SNP of the gene CTD-2325M2.1 in Cortex eQTL GTEx omic data for FTD and is it functionally significant? | There are no SNPs within the gene CTD-2325M2.1 in Cortex eQTL GTEx omic data that are significantly associated with FTD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CTD-2325M2.1" AND Disease = "FTD" AND LOWER(Omic_type) LIKE "%cortex eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1254886', 'topRSID': 'rs8112595', 'Disease': 'FTD', 'Gene': 'CTD-2325M2.1', 'p_SMR_multi': 0.7164764, 'p_HEIDI': 0.9953197, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL GTEx', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1807 | Q67 | What is the top-associated SNP of the gene SNCA in Whole Brain meta-analysis mQTL omic data for LBD and is it functionally significant? | The top-associated SNP for SNCA in Whole Brain meta-analysis mQTL omic data for LBD is rs1372520, which has a multi-SNP SMR p-value of 2.50e-06 and a HEIDI of 0.13, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SNCA" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_338827', 'topRSID': 'rs3756059', 'Disease': 'LBD', 'Gene': 'SNCA', 'p_SMR_multi': 4.824404e-10, 'p_HEIDI': 0.0002321407, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.661 | Q67 | What is the top-associated SNP of the gene RP11-259G18.2 in Cerebellar Hemisphere eQTL omic data for PD and is it functionally significant? | The top-associated SNP for RP11-259G18.2 in Cerebellar Hemisphere eQTL omic data for PD is rs17763086, which has a multi-SNP SMR p-value of 1.83e-11 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.2" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cerebellar hemisphere eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1191173', 'topRSID': 'rs17763086', 'Disease': 'PD', 'Gene': 'RP11-259G18.2', 'p_SMR_multi': 1.833659e-11, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Cerebellar Hemisphere', 'Omic_type': 'Cerebellar Hemisphere eQTL', 'func_sig': 'association meets significance threshold but shows signs ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.560 | Q67 | What is the top-associated SNP of the gene MAPT in Whole Brain meta-analysis mQTL omic data for PSP and is it functionally significant? | The top-associated SNP for MAPT in Whole Brain meta-analysis mQTL omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 2.10e-44 and a HEIDI of 0.01, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_560864', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'MAPT', 'p_SMR_multi': 2.100115e-44, 'p_HEIDI': 0.01425494, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_56... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
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