uuid stringlengths 4 8 | template_uuid stringclasses 40
values | question stringlengths 13 193 | answer stringlengths 29 2.2k | benchmark_query stringlengths 133 622 | execution_results stringlengths 2 1.14M | query_type stringclasses 2
values | sql_category stringclasses 26
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|---|---|---|---|---|---|---|---|---|
Q67.1212 | Q67 | What is the top-associated SNP of the gene PVRL2 in Liver eQTL omic data for AD and is it functionally significant? | The top-associated SNP for PVRL2 in Liver eQTL omic data for AD is rs440277, which has a multi-SNP SMR p-value of 8.96e-13 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PVRL2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%liver eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1466877', 'topRSID': 'rs440277', 'Disease': 'AD', 'Gene': 'PVRL2', 'p_SMR_multi': 8.956061e-13, 'p_HEIDI': 5.459670000000001e-23, 'Omic_tissue': 'Liver', 'Omic_type': 'Liver eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequil... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.971 | Q67 | What is the top-associated SNP of the gene CR2 in Prefrontal Cortex eQTL omic data for AD and is it functionally significant? | The top-associated SNP for CR2 in Prefrontal Cortex eQTL omic data for AD is rs1019830, which has a multi-SNP SMR p-value of 8.03e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CR2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%prefrontal cortex eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1195475', 'topRSID': 'rs1019830', 'Disease': 'AD', 'Gene': 'CR2', 'p_SMR_multi': 8.027354e-09, 'p_HEIDI': 0.0001062646, 'Omic_tissue': 'Prefrontal Cortex', 'Omic_type': 'Prefrontal Cortex eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Li... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.805 | Q67 | What is the top-associated SNP of the gene KANSL1 in Cortex eQTL metaBrain omic data for AD and is it functionally significant? | The top-associated SNP for KANSL1 in Cortex eQTL metaBrain omic data for AD is rs199457, which has a multi-SNP SMR p-value of 7.58e-07 and a HEIDI of 0.92, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%cortex eqtl metabrain%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1106830', 'topRSID': 'rs199457', 'Disease': 'AD', 'Gene': 'KANSL1', 'p_SMR_multi': 7.577246e-07, 'p_HEIDI': 0.9173582, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL metaBrain', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.121 | Q67 | What is the top-associated SNP of the gene SOX6 in Whole Blood mQTL omic data for LBD and is it functionally significant? | There are no SNPs within the gene SOX6 in Whole Blood mQTL omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SOX6" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_901468', 'topRSID': 'rs2615035', 'Disease': 'LBD', 'Gene': 'SOX6', 'p_SMR_multi': 0.02046946, 'p_HEIDI': 0.03845073, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_901471', 'topR... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1322 | Q67 | What is the top-associated SNP of the gene KANSL1 in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for KANSL1 in Whole Blood mQTL omic data for PD is rs112197756, which has a multi-SNP SMR p-value of 1.85e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_948907', 'topRSID': 'rs2532233', 'Disease': 'PD', 'Gene': 'KANSL1', 'p_SMR_multi': 1.024112e-14, 'p_HEIDI': 2.989456e-05, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dise... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1221 | Q67 | What is the top-associated SNP of the gene PSORS1C1 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for PSORS1C1 in Whole Blood mQTL omic data for AD is rs141943201, which has a multi-SNP SMR p-value of 8.09e-07 and a HEIDI of 0.31, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PSORS1C1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_620729', 'topRSID': 'rs9501055', 'Disease': 'AD', 'Gene': 'PSORS1C1', 'p_SMR_multi': 5.485384e-08, 'p_HEIDI': 0.004858996, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dis... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.528 | Q67 | What is the top-associated SNP of the gene KANSL1 in Whole Blood mQTL omic data for PSP and is it functionally significant? | The top-associated SNP for KANSL1 in Whole Blood mQTL omic data for PSP is rs11012, which has a multi-SNP SMR p-value of 1.80e-08 and a HEIDI of 0.5, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1041761', 'topRSID': 'rs169201', 'Disease': 'PSP', 'Gene': 'KANSL1', 'p_SMR_multi': 3.489683e-40, 'p_HEIDI': 3.497522e-13, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dis... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.519 | Q67 | What is the top-associated SNP of the gene RP11-745O10.2 in Cerebellum eQTL omic data for FTD and is it functionally significant? | There are no SNPs within the gene RP11-745O10.2 in Cerebellum eQTL omic data that are significantly associated with FTD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-745O10.2" AND Disease = "FTD" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1699282', 'topRSID': 'rs1168770', 'Disease': 'FTD', 'Gene': 'RP11-745O10.2', 'p_SMR_multi': 0.8909065, 'p_HEIDI': 0.9817544, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.84 | Q67 | What is the top-associated SNP of the gene IDUA in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for IDUA in Whole Blood mQTL omic data for PD is rs6964, which has a multi-SNP SMR p-value of 1.28e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "IDUA" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_996313', 'topRSID': 'rs11936407', 'Disease': 'PD', 'Gene': 'IDUA', 'p_SMR_multi': 1.158943e-09, 'p_HEIDI': 4.775076e-12, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.717 | Q67 | What is the top-associated SNP of the gene C19orf6 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for C19orf6 in Whole Blood mQTL omic data for AD is rs7251792, which has a multi-SNP SMR p-value of 1.60e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "C19orf6" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_634274', 'topRSID': 'rs4807395', 'Disease': 'AD', 'Gene': 'C19orf6', 'p_SMR_multi': 1.492903e-06, 'p_HEIDI': 0.0003908802, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dis... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1185 | Q67 | What is the top-associated SNP of the gene UBA6 in Whole Blood eQTL eQTLgen omic data for ALS and is it functionally significant? | There are no SNPs within the gene UBA6 in Whole Blood eQTL eQTLgen omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "UBA6" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1509169', 'topRSID': 'rs12498800', 'Disease': 'ALS', 'Gene': 'UBA6', 'p_SMR_multi': 0.5243552, 'p_HEIDI': 0.4140819, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.386 | Q67 | What is the top-associated SNP of the gene ARL17A in Cerebellum eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for ARL17A in Cerebellum eQTL omic data for PSP is rs393152, which has a multi-SNP SMR p-value of 7.06e-30 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARL17A" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_22221', 'topRSID': 'rs393152', 'Disease': 'PSP', 'Gene': 'ARL17A', 'p_SMR_multi': 7.062669e-30, 'p_HEIDI': 1.359857e-15, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequi... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1022 | Q67 | What is the top-associated SNP of the gene PTPN7 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for LBD and is it functionally significant? | There are no SNPs within the gene PTPN7 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PTPN7" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1419006', 'topRSID': 'rs2993427', 'Disease': 'LBD', 'Gene': 'PTPN7', 'p_SMR_multi': 0.3609737, 'p_HEIDI': 0.7259276, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1689 | Q67 | What is the top-associated SNP of the gene RP11-67M1.1 in Whole Brain eQTL omic data for FTD and is it functionally significant? | There are no SNPs within the gene RP11-67M1.1 in Whole Brain eQTL omic data that are significantly associated with FTD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-67M1.1" AND Disease = "FTD" AND LOWER(Omic_type) LIKE "%whole brain eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1621541', 'topRSID': 'rs920624', 'Disease': 'FTD', 'Gene': 'RP11-67M1.1', 'p_SMR_multi': 0.9590994, 'p_HEIDI': 0.7597156, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.87 | Q67 | What is the top-associated SNP of the gene OR2A5 in Whole Blood mQTL omic data for PSP and is it functionally significant? | There are no SNPs within the gene OR2A5 in Whole Blood mQTL omic data that are significantly associated with PSP, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "OR2A5" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1050083', 'topRSID': 'rs7779313', 'Disease': 'PSP', 'Gene': 'OR2A5', 'p_SMR_multi': 0.8230022, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1684 | Q67 | What is the top-associated SNP of the gene GPX4 in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for GPX4 in Whole Blood eQTL eQTLgen omic data for AD is rs8103188, which has a multi-SNP SMR p-value of 6.03e-13 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "GPX4" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1503135', 'topRSID': 'rs8103188', 'Disease': 'AD', 'Gene': 'GPX4', 'p_SMR_multi': 6.033717e-13, 'p_HEIDI': 0.0001981533, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linka... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.333 | Q67 | What is the top-associated SNP of the gene ARL17B in Whole Blood eQTL GTEx omic data for PD and is it functionally significant? | The top-associated SNP for ARL17B in Whole Blood eQTL GTEx omic data for PD is rs62074125, which has a multi-SNP SMR p-value of 1.10e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARL17B" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1679569', 'topRSID': 'rs62074125', 'Disease': 'PD', 'Gene': 'ARL17B', 'p_SMR_multi': 1.098175e-06, 'p_HEIDI': 0.004180717, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL GTEx', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkag... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.7 | Q67 | What is the top-associated SNP of the gene RP11-259G18.3 in Cerebellar Hemisphere eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for RP11-259G18.3 in Cerebellar Hemisphere eQTL omic data for PSP is rs169201, which has a multi-SNP SMR p-value of 4.74e-19 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.3" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%cerebellar hemisphere eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1194219', 'topRSID': 'rs169201', 'Disease': 'PSP', 'Gene': 'RP11-259G18.3', 'p_SMR_multi': 4.740741e-19, 'p_HEIDI': 1.588974e-09, 'Omic_tissue': 'Cerebellar Hemisphere', 'Omic_type': 'Cerebellar Hemisphere eQTL', 'func_sig': 'association meets significance threshold but shows si... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.737 | Q67 | What is the top-associated SNP of the gene CRHR1-IT1 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for CRHR1-IT1 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for PSP is rs12373139, which has a multi-SNP SMR p-value of 3.11e-32 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CRHR1-IT1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT... | [{'UUID': 'NDD_SMR_genes_all_update_text_1444270', 'topRSID': 'rs12373139', 'Disease': 'PSP', 'Gene': 'CRHR1-IT1', 'p_SMR_multi': 3.109827e-32, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'association meets significance thres... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.750 | Q67 | What is the top-associated SNP of the gene AC005013.5 in Caudate Basal Ganglia eQTL omic data for FTD and is it functionally significant? | There are no SNPs within the gene AC005013.5 in Caudate Basal Ganglia eQTL omic data that are significantly associated with FTD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "AC005013.5" AND Disease = "FTD" AND LOWER(Omic_type) LIKE "%caudate basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1273379', 'topRSID': 'rs1006521', 'Disease': 'FTD', 'Gene': 'AC005013.5', 'p_SMR_multi': 0.2195339, 'p_HEIDI': 0.9089552, 'Omic_tissue': 'Caudate Basal Ganglia', 'Omic_type': 'Caudate Basal Ganglia eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1414 | Q67 | What is the top-associated SNP of the gene MAPT in Whole Brain meta-analysis mQTL omic data for PSP and is it functionally significant? | The top-associated SNP for MAPT in Whole Brain meta-analysis mQTL omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 4.32e-27 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_560864', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'MAPT', 'p_SMR_multi': 2.100115e-44, 'p_HEIDI': 0.01425494, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_56... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1751 | Q67 | What is the top-associated SNP of the gene ARL17A in Hippocampus eQTL omic data for PD and is it functionally significant? | The top-associated SNP for ARL17A in Hippocampus eQTL omic data for PD is rs3785884, which has a multi-SNP SMR p-value of 2.77e-09 and a HEIDI of 0.27, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARL17A" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%hippocampus eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_33018', 'topRSID': 'rs3785884', 'Disease': 'PD', 'Gene': 'ARL17A', 'p_SMR_multi': 2.771664e-09, 'p_HEIDI': 0.2724067, 'Omic_tissue': 'Hippocampus', 'Omic_type': 'Hippocampus eQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_1386998', 'topRSI... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.457 | Q67 | What is the top-associated SNP of the gene MAPT in Whole Blood mQTL omic data for PSP and is it functionally significant? | The top-associated SNP for MAPT in Whole Blood mQTL omic data for PSP is rs11012, which has a multi-SNP SMR p-value of 1.78e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1041740', 'topRSID': 'rs169201', 'Disease': 'PSP', 'Gene': 'MAPT', 'p_SMR_multi': 3.1929999999999995e-44, 'p_HEIDI': 3.11336e-12, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Link... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.496 | Q67 | What is the top-associated SNP of the gene KANSL1 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for KANSL1 in Whole Brain meta-analysis mQTL omic data for PD is rs1966345, which has a multi-SNP SMR p-value of 2.37e-15 and a HEIDI of 0.23, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_491139', 'topRSID': 'rs12150087', 'Disease': 'PD', 'Gene': 'KANSL1', 'p_SMR_multi': 8.107128999999999e-20, 'p_HEIDI': 0.009069932, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs o... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1482 | Q67 | What is the top-associated SNP of the gene RP11-259G18.2 in Nucleus Accumbens Basal Ganglia omic data for PD and is it functionally significant? | The top-associated SNP for RP11-259G18.2 in Nucleus Accumbens Basal Ganglia omic data for PD is rs55974014, which has a multi-SNP SMR p-value of 1.30e-11 and a HEIDI of 0.27, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.2" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%nucleus accumbens basal ganglia%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1730066', 'topRSID': 'rs55974014', 'Disease': 'PD', 'Gene': 'RP11-259G18.2', 'p_SMR_multi': 1.298891e-11, 'p_HEIDI': 0.2715299, 'Omic_tissue': 'Nucleus Accumbens Basal', 'Omic_type': 'Nucleus Accumbens Basal Ganglia', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.291 | Q67 | What is the top-associated SNP of the gene CDIPT-AS1 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for CDIPT-AS1 in Whole Blood mQTL omic data for AD is rs889695, which has a multi-SNP SMR p-value of 5.98e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CDIPT-AS1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_577403', 'topRSID': 'rs889695', 'Disease': 'AD', 'Gene': 'CDIPT-AS1', 'p_SMR_multi': 5.983115e-07, 'p_HEIDI': 2.959687e-05, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Di... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1817 | Q67 | What is the top-associated SNP of the gene CRHR1-IT1 in Amygdala eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for CRHR1-IT1 in Amygdala eQTL omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 1.21e-15 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CRHR1-IT1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%amygdala eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1604712', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'CRHR1-IT1', 'p_SMR_multi': 1.212366e-15, 'p_HEIDI': 6.830086e-17, 'Omic_tissue': 'Amygdala', 'Omic_type': 'Amygdala eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1986 | Q67 | What is the top-associated SNP of the gene PLEKHM1 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for PLEKHM1 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 2.19e-22 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PLEKHM1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT 1... | [{'UUID': 'NDD_SMR_genes_all_update_text_1444268', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'PLEKHM1', 'p_SMR_multi': 2.18827e-22, 'p_HEIDI': 3.217897e-34, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'association meets significance thre... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1370 | Q67 | What is the top-associated SNP of the gene HSD3B7 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for HSD3B7 in Whole Brain meta-analysis mQTL omic data for PD is rs8060857, which has a multi-SNP SMR p-value of 8.00e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "HSD3B7" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_485447', 'topRSID': 'rs8060857', 'Disease': 'PD', 'Gene': 'HSD3B7', 'p_SMR_multi': 7.997804e-08, 'p_HEIDI': 0.00668826, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.893 | Q67 | What is the top-associated SNP of the gene RGS12 in Whole Blood mQTL omic data for FTD and is it functionally significant? | There are no SNPs within the gene RGS12 in Whole Blood mQTL omic data that are significantly associated with FTD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RGS12" AND Disease = "FTD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_840984', 'topRSID': 'rs1320762', 'Disease': 'FTD', 'Gene': 'RGS12', 'p_SMR_multi': 0.1600814, 'p_HEIDI': 0.7715126, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_840988', 'topRS... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1063 | Q67 | What is the top-associated SNP of the gene LRRC37A4P in Cerebellar Hemisphere eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for LRRC37A4P in Cerebellar Hemisphere eQTL omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 2.80e-19 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A4P" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%cerebellar hemisphere eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1194210', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'LRRC37A4P', 'p_SMR_multi': 2.800524e-19, 'p_HEIDI': 7.896035e-24, 'Omic_tissue': 'Cerebellar Hemisphere', 'Omic_type': 'Cerebellar Hemisphere eQTL', 'func_sig': 'association meets significance threshold but shows signs... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1846 | Q67 | What is the top-associated SNP of the gene GAK in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for GAK in Whole Blood mQTL omic data for PD is rs12651271, which has a multi-SNP SMR p-value of 2.45e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "GAK" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_996273', 'topRSID': 'rs12651271', 'Disease': 'PD', 'Gene': 'GAK', 'p_SMR_multi': 6.180527e-09, 'p_HEIDI': 3.619298e-07, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1982 | Q67 | What is the top-associated SNP of the gene LRRC37A4P in Cortex eQTL GTEx omic data for PD and is it functionally significant? | The top-associated SNP for LRRC37A4P in Cortex eQTL GTEx omic data for PD is rs62063271, which has a multi-SNP SMR p-value of 1.12e-12 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A4P" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cortex eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1262219', 'topRSID': 'rs62063271', 'Disease': 'PD', 'Gene': 'LRRC37A4P', 'p_SMR_multi': 1.116506e-12, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL GTEx', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequili... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.789 | Q67 | What is the top-associated SNP of the gene MFSD4 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | There are no SNPs within the gene MFSD4 in Whole Brain meta-analysis mQTL omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MFSD4" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_416995', 'topRSID': 'rs3747968', 'Disease': 'PD', 'Gene': 'MFSD4', 'p_SMR_multi': 0.008383401, 'p_HEIDI': 0.02311377, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.866 | Q67 | What is the top-associated SNP of the gene PVRIG in Cerebellum eQTL omic data for AD and is it functionally significant? | The top-associated SNP for PVRIG in Cerebellum eQTL omic data for AD is rs1727140, which has a multi-SNP SMR p-value of 3.43e-08 and a HEIDI of 0.07, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PVRIG" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1687934', 'topRSID': 'rs1727140', 'Disease': 'AD', 'Gene': 'PVRIG', 'p_SMR_multi': 3.434503e-08, 'p_HEIDI': 0.06813768, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_273', 'topRSID': ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1306 | Q67 | What is the top-associated SNP of the gene CEACAM19 in Whole Blood eQTL GTEx omic data for AD and is it functionally significant? | The top-associated SNP for CEACAM19 in Whole Blood eQTL GTEx omic data for AD is rs714948, which has a multi-SNP SMR p-value of 8.58e-07 and a HEIDI of 0.02, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CEACAM19" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1653156', 'topRSID': 'rs714948', 'Disease': 'AD', 'Gene': 'CEACAM19', 'p_SMR_multi': 8.575738e-07, 'p_HEIDI': 0.01715121, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL GTEx', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1088 | Q67 | What is the top-associated SNP of the gene LRRC37A4P in Whole Blood eQTL eQTLgen omic data for PSP and is it functionally significant? | The top-associated SNP for LRRC37A4P in Whole Blood eQTL eQTLgen omic data for PSP is rs11012, which has a multi-SNP SMR p-value of 2.64e-18 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A4P" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1579415', 'topRSID': 'rs11012', 'Disease': 'PSP', 'Gene': 'LRRC37A4P', 'p_SMR_multi': 2.6425950000000002e-18, 'p_HEIDI': 7.709293e-09, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1889 | Q67 | What is the top-associated SNP of the gene AC005154.6 in Substantia nigra eQTL omic data for AD and is it functionally significant? | There are no SNPs within the gene AC005154.6 in Substantia nigra eQTL omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "AC005154.6" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%substantia nigra eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1446196', 'topRSID': 'rs2529437', 'Disease': 'AD', 'Gene': 'AC005154.6', 'p_SMR_multi': 0.2570343, 'p_HEIDI': 0.1099667, 'Omic_tissue': 'Substantia nigra', 'Omic_type': 'Substantia nigra eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.331 | Q67 | What is the top-associated SNP of the gene NKAIN4 in Anterior Cingulate Cortex BA24 eQTL omic data for PD and is it functionally significant? | There are no SNPs within the gene NKAIN4 in Anterior Cingulate Cortex BA24 eQTL omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "NKAIN4" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%anterior cingulate cortex ba24 eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1488412', 'topRSID': 'rs78017705', 'Disease': 'PD', 'Gene': 'NKAIN4', 'p_SMR_multi': 0.6697732, 'p_HEIDI': 0.1137404, 'Omic_tissue': 'Anterior Cingulate Cortex BA24', 'Omic_type': 'Anterior Cingulate Cortex BA24 eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.448 | Q67 | What is the top-associated SNP of the gene ARHGAP27 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for ARHGAP27 in Whole Brain meta-analysis mQTL omic data for PD is rs62064597, which has a multi-SNP SMR p-value of 7.34e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARHGAP27" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_491057', 'topRSID': 'rs62065376', 'Disease': 'PD', 'Gene': 'ARHGAP27', 'p_SMR_multi': 1.134698e-11, 'p_HEIDI': 0.3072466, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.766 | Q67 | What is the top-associated SNP of the gene NADSYN1 in Whole Brain meta-analysis mQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene NADSYN1 in Whole Brain meta-analysis mQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "NADSYN1" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_188333', 'topRSID': 'rs7949129', 'Disease': 'ALS', 'Gene': 'NADSYN1', 'p_SMR_multi': 0.05794293, 'p_HEIDI': 0.1978104, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_tex... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1844 | Q67 | What is the top-associated SNP of the gene SNCA in Whole Blood mQTL omic data for LBD and is it functionally significant? | The top-associated SNP for SNCA in Whole Blood mQTL omic data for LBD is rs1372520, which has a multi-SNP SMR p-value of 1.86e-08 and a HEIDI of 0.09, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SNCA" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_934862', 'topRSID': 'rs2301134', 'Disease': 'LBD', 'Gene': 'SNCA', 'p_SMR_multi': 3.123872e-10, 'p_HEIDI': 0.8604982, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_934864', 'topRSID... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.913 | Q67 | What is the top-associated SNP of the gene IDUA in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for IDUA in Whole Blood mQTL omic data for PD is rs11248060, which has a multi-SNP SMR p-value of 1.47e-07 and a HEIDI of 0.08, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "IDUA" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_996313', 'topRSID': 'rs11936407', 'Disease': 'PD', 'Gene': 'IDUA', 'p_SMR_multi': 1.158943e-09, 'p_HEIDI': 4.775076e-12, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1141 | Q67 | What is the top-associated SNP of the gene KANSL1-AS1 in Anterior Cingulate Cortex BA24 eQTL omic data for PD and is it functionally significant? | The top-associated SNP for KANSL1-AS1 in Anterior Cingulate Cortex BA24 eQTL omic data for PD is rs199533, which has a multi-SNP SMR p-value of 6.63e-11 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1-AS1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%anterior cingulate cortex ba24 eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1488140', 'topRSID': 'rs199533', 'Disease': 'PD', 'Gene': 'KANSL1-AS1', 'p_SMR_multi': 6.633594e-11, 'p_HEIDI': 0.009088412, 'Omic_tissue': 'Anterior Cingulate Cortex BA24', 'Omic_type': 'Anterior Cingulate Cortex BA24 eQTL', 'func_sig': 'association meets significance threshold... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.180 | Q67 | What is the top-associated SNP of the gene EPHX2 in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for EPHX2 in Whole Blood eQTL eQTLgen omic data for AD is rs1126452, which has a multi-SNP SMR p-value of 4.45e-16 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "EPHX2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1496307', 'topRSID': 'rs1126452', 'Disease': 'AD', 'Gene': 'EPHX2', 'p_SMR_multi': 4.445184e-16, 'p_HEIDI': 6.513073e-14, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Link... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.729 | Q67 | What is the top-associated SNP of the gene CPNE8 in Whole Blood eQTL eQTLgen omic data for PD and is it functionally significant? | There are no SNPs within the gene CPNE8 in Whole Blood eQTL eQTLgen omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CPNE8" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1561425', 'topRSID': 'rs111452282', 'Disease': 'PD', 'Gene': 'CPNE8', 'p_SMR_multi': 0.2169224, 'p_HEIDI': 0.6180909, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1273 | Q67 | What is the top-associated SNP of the gene FAM200B in Whole Blood eQTL eQTLgen omic data for PD and is it functionally significant? | The top-associated SNP for FAM200B in Whole Blood eQTL eQTLgen omic data for PD is rs6816982, which has a multi-SNP SMR p-value of 5.39e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "FAM200B" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1555729', 'topRSID': 'rs6816982', 'Disease': 'PD', 'Gene': 'FAM200B', 'p_SMR_multi': 5.387965e-08, 'p_HEIDI': 3.006393e-06, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Li... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.89 | Q67 | What is the top-associated SNP of the gene CRHR1-IT1 in Tibial Nerve eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for CRHR1-IT1 in Tibial Nerve eQTL omic data for PSP is rs12373139, which has a multi-SNP SMR p-value of 2.25e-33 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CRHR1-IT1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%tibial nerve eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1336288', 'topRSID': 'rs12373139', 'Disease': 'PSP', 'Gene': 'CRHR1-IT1', 'p_SMR_multi': 2.2496390000000006e-33, 'p_HEIDI': 3.916149e-19, 'Omic_tissue': 'Tibial Nerve', 'Omic_type': 'Tibial Nerve eQTL', 'func_sig': 'association meets significance threshold but shows signs of lin... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1410 | Q67 | What is the top-associated SNP of the gene TMEM175 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for TMEM175 in Whole Brain meta-analysis mQTL omic data for PD is rs6842808, which has a multi-SNP SMR p-value of 2.31e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TMEM175" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_429841', 'topRSID': 'rs10008187', 'Disease': 'PD', 'Gene': 'TMEM175', 'p_SMR_multi': 4.414637e-10, 'p_HEIDI': 0.4333231, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1900 | Q67 | What is the top-associated SNP of the gene CRHR1 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for CRHR1 in Whole Brain meta-analysis mQTL omic data for PD is rs453997, which has a multi-SNP SMR p-value of 9.55e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CRHR1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_491090', 'topRSID': 'rs878888', 'Disease': 'PD', 'Gene': 'CRHR1', 'p_SMR_multi': 1.344956e-12, 'p_HEIDI': 0.1584008, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_4910... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.463 | Q67 | What is the top-associated SNP of the gene ZBTB46 in Whole Brain meta-analysis mQTL omic data for FTD and is it functionally significant? | There are no SNPs within the gene ZBTB46 in Whole Brain meta-analysis mQTL omic data that are significantly associated with FTD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ZBTB46" AND Disease = "FTD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_313477', 'topRSID': 'rs58150746', 'Disease': 'FTD', 'Gene': 'ZBTB46', 'p_SMR_multi': 0.06847386, 'p_HEIDI': 0.1023552, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_tex... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1830 | Q67 | What is the top-associated SNP of the gene ARL17A in Nucleus Accumbens Basal Ganglia omic data for PD and is it functionally significant? | The top-associated SNP for ARL17A in Nucleus Accumbens Basal Ganglia omic data for PD is rs58879558, which has a multi-SNP SMR p-value of 7.11e-11 and a HEIDI of 0.17, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARL17A" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%nucleus accumbens basal ganglia%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1730073', 'topRSID': 'rs58879558', 'Disease': 'PD', 'Gene': 'ARL17A', 'p_SMR_multi': 7.112257e-11, 'p_HEIDI': 0.1695124, 'Omic_tissue': 'Nucleus Accumbens Basal', 'Omic_type': 'Nucleus Accumbens Basal Ganglia', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.55 | Q67 | What is the top-associated SNP of the gene KANSL1 in Hippocampus eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for KANSL1 in Hippocampus eQTL omic data for PSP is rs169201, which has a multi-SNP SMR p-value of 3.68e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%hippocampus eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_33471', 'topRSID': 'rs169201', 'Disease': 'PSP', 'Gene': 'KANSL1', 'p_SMR_multi': 3.683534e-10, 'p_HEIDI': 9.338251e-05, 'Omic_tissue': 'Hippocampus', 'Omic_type': 'Hippocampus eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1503 | Q67 | What is the top-associated SNP of the gene RP11-707O23.5 in Amygdala eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for RP11-707O23.5 in Amygdala eQTL omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 6.08e-15 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-707O23.5" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%amygdala eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1604711', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'RP11-707O23.5', 'p_SMR_multi': 6.082386e-15, 'p_HEIDI': 1.048533e-16, 'Omic_tissue': 'Amygdala', 'Omic_type': 'Amygdala eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage D... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.650 | Q67 | What is the top-associated SNP of the gene SPI1 in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for SPI1 in Whole Blood eQTL eQTLgen omic data for AD is rs11570034, which has a multi-SNP SMR p-value of 3.74e-07 and a HEIDI of 0.44, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SPI1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1498213', 'topRSID': 'rs11570034', 'Disease': 'AD', 'Gene': 'SPI1', 'p_SMR_multi': 3.736983e-07, 'p_HEIDI': 0.437956, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.684 | Q67 | What is the top-associated SNP of the gene INO80B in Whole Blood eQTL eQTLgen omic data for FTD and is it functionally significant? | There are no SNPs within the gene INO80B in Whole Blood eQTL eQTLgen omic data that are significantly associated with FTD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "INO80B" AND Disease = "FTD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1523015', 'topRSID': 'rs2268416', 'Disease': 'FTD', 'Gene': 'INO80B', 'p_SMR_multi': 0.6321188, 'p_HEIDI': 0.4249855, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.224 | Q67 | What is the top-associated SNP of the gene ARHGAP27 in Nucleus Accumbens Basal Ganglia omic data for PD and is it functionally significant? | The top-associated SNP for ARHGAP27 in Nucleus Accumbens Basal Ganglia omic data for PD is rs753236, which has a multi-SNP SMR p-value of 3.65e-10 and a HEIDI of 0.95, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARHGAP27" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%nucleus accumbens basal ganglia%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1730056', 'topRSID': 'rs753236', 'Disease': 'PD', 'Gene': 'ARHGAP27', 'p_SMR_multi': 3.652036e-10, 'p_HEIDI': 0.9455297, 'Omic_tissue': 'Nucleus Accumbens Basal', 'Omic_type': 'Nucleus Accumbens Basal Ganglia', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.116 | Q67 | What is the top-associated SNP of the gene AC002480.5 in Whole Brain meta-analysis mQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene AC002480.5 in Whole Brain meta-analysis mQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "AC002480.5" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_167672', 'topRSID': 'rs17300609', 'Disease': 'ALS', 'Gene': 'AC002480.5', 'p_SMR_multi': 0.9137895, 'p_HEIDI': 0.9889255, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1552 | Q67 | What is the top-associated SNP of the gene IDUA in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for IDUA in Whole Blood mQTL omic data for PD is rs62294519, which has a multi-SNP SMR p-value of 2.00e-08 and a HEIDI of 0.05, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "IDUA" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_996313', 'topRSID': 'rs11936407', 'Disease': 'PD', 'Gene': 'IDUA', 'p_SMR_multi': 1.158943e-09, 'p_HEIDI': 4.775076e-12, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1303 | Q67 | What is the top-associated SNP of the gene LRRC37A in Nucleus Accumbens Basal Ganglia omic data for PD and is it functionally significant? | The top-associated SNP for LRRC37A in Nucleus Accumbens Basal Ganglia omic data for PD is rs3874943, which has a multi-SNP SMR p-value of 5.67e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%nucleus accumbens basal ganglia%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1730070', 'topRSID': 'rs3874943', 'Disease': 'PD', 'Gene': 'LRRC37A', 'p_SMR_multi': 5.67403e-08, 'p_HEIDI': 1.223912e-08, 'Omic_tissue': 'Nucleus Accumbens Basal', 'Omic_type': 'Nucleus Accumbens Basal Ganglia', 'func_sig': 'association meets significance threshold but shows si... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.987 | Q67 | What is the top-associated SNP of the gene EFNA4 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for EFNA4 in Whole Brain meta-analysis mQTL omic data for PD is rs11264304, which has a multi-SNP SMR p-value of 2.84e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "EFNA4" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_415494', 'topRSID': 'rs3765087', 'Disease': 'PD', 'Gene': 'EFNA4', 'p_SMR_multi': 1.676525e-06, 'p_HEIDI': 0.02066825, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_41... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.177 | Q67 | What is the top-associated SNP of the gene C9orf72 in Whole Blood mQTL omic data for ALS and is it functionally significant? | The top-associated SNP for C9orf72 in Whole Blood mQTL omic data for ALS is rs9969832, which has a multi-SNP SMR p-value of 6.71e-11 and a HEIDI of 0.68, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "C9orf72" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_745097', 'topRSID': 'rs2282241', 'Disease': 'ALS', 'Gene': 'C9orf72', 'p_SMR_multi': 1.85908e-11, 'p_HEIDI': 7.971389e-13, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dis... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1650 | Q67 | What is the top-associated SNP of the gene RABAC1 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene RABAC1 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RABAC1" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT 10... | [{'UUID': 'NDD_SMR_genes_all_update_text_1407483', 'topRSID': 'rs1864207', 'Disease': 'ALS', 'Gene': 'RABAC1', 'p_SMR_multi': 0.2200814, 'p_HEIDI': 0.5079992, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.596 | Q67 | What is the top-associated SNP of the gene PDE6B in Whole Brain meta-analysis mQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene PDE6B in Whole Brain meta-analysis mQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PDE6B" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_149423', 'topRSID': 'rs7669178', 'Disease': 'ALS', 'Gene': 'PDE6B', 'p_SMR_multi': 0.1682228, 'p_HEIDI': 0.7155074, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_1... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1560 | Q67 | What is the top-associated SNP of the gene ARL17B in Tibial Nerve eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for ARL17B in Tibial Nerve eQTL omic data for PSP is rs3785883, which has a multi-SNP SMR p-value of 1.99e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARL17B" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%tibial nerve eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1336295', 'topRSID': 'rs3785883', 'Disease': 'PSP', 'Gene': 'ARL17B', 'p_SMR_multi': 1.990803e-06, 'p_HEIDI': 0.0001527845, 'Omic_tissue': 'Tibial Nerve', 'Omic_type': 'Tibial Nerve eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.19 | Q67 | What is the top-associated SNP of the gene KANSL1-AS1 in Cerebellum eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for KANSL1-AS1 in Cerebellum eQTL omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 8.57e-22 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1-AS1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1714156', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'KANSL1-AS1', 'p_SMR_multi': 8.571901000000001e-22, 'p_HEIDI': 5.305356000000001e-17, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'association meets significance threshold but shows signs of... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.429 | Q67 | What is the top-associated SNP of the gene AC008984.2 in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for AC008984.2 in Whole Blood eQTL eQTLgen omic data for AD is rs1761453, which has a multi-SNP SMR p-value of 2.02e-06 and a HEIDI of 0.06, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "AC008984.2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1504183', 'topRSID': 'rs1761453', 'Disease': 'AD', 'Gene': 'AC008984.2', 'p_SMR_multi': 2.023069e-06, 'p_HEIDI': 0.05770473, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1345 | Q67 | What is the top-associated SNP of the gene SPPL2C in Cerebellum eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for SPPL2C in Cerebellum eQTL omic data for PSP is rs393152, which has a multi-SNP SMR p-value of 1.26e-19 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SPPL2C" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_22216', 'topRSID': 'rs393152', 'Disease': 'PSP', 'Gene': 'SPPL2C', 'p_SMR_multi': 1.259583e-19, 'p_HEIDI': 4.385134e-16, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequi... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.289 | Q67 | What is the top-associated SNP of the gene RASA3 in Whole Brain meta-analysis mQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene RASA3 in Whole Brain meta-analysis mQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RASA3" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_197518', 'topRSID': 'rs9314899', 'Disease': 'ALS', 'Gene': 'RASA3', 'p_SMR_multi': 0.02859751, 'p_HEIDI': 0.0198406, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1584 | Q67 | What is the top-associated SNP of the gene STAG3 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for STAG3 in Whole Brain meta-analysis mQTL omic data for AD is rs11767968, which has a multi-SNP SMR p-value of 1.17e-11 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "STAG3" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_74050', 'topRSID': 'rs11767968', 'Disease': 'AD', 'Gene': 'STAG3', 'p_SMR_multi': 1.165779e-11, 'p_HEIDI': 8.480336e-05, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.434 | Q67 | What is the top-associated SNP of the gene MS4A6A in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for MS4A6A in Whole Brain meta-analysis mQTL omic data for AD is rs614104, which has a multi-SNP SMR p-value of 1.42e-06 and a HEIDI of 0.02, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MS4A6A" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_91391', 'topRSID': 'rs614104', 'Disease': 'AD', 'Gene': 'MS4A6A', 'p_SMR_multi': 1.424615e-06, 'p_HEIDI': 0.01796425, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_913... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1640 | Q67 | What is the top-associated SNP of the gene RP11-259G18.2 in Whole Blood eQTL GTEx omic data for AD and is it functionally significant? | The top-associated SNP for RP11-259G18.2 in Whole Blood eQTL GTEx omic data for AD is rs55974014, which has a multi-SNP SMR p-value of 5.29e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1652500', 'topRSID': 'rs55974014', 'Disease': 'AD', 'Gene': 'RP11-259G18.2', 'p_SMR_multi': 5.286305e-07, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL GTEx', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Lin... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1245 | Q67 | What is the top-associated SNP of the gene CXXC11 in Whole Blood eQTL eQTLgen omic data for PD and is it functionally significant? | There are no SNPs within the gene CXXC11 in Whole Blood eQTL eQTLgen omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CXXC11" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1554757', 'topRSID': 'rs28512331', 'Disease': 'PD', 'Gene': 'CXXC11', 'p_SMR_multi': 0.9676279, 'p_HEIDI': 0.1954235, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.676 | Q67 | What is the top-associated SNP of the gene RP11-259G18.1 in Cortex eQTL GTEx omic data for PD and is it functionally significant? | The top-associated SNP for RP11-259G18.1 in Cortex eQTL GTEx omic data for PD is rs17652520, which has a multi-SNP SMR p-value of 5.31e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cortex eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1262228', 'topRSID': 'rs17652520', 'Disease': 'PD', 'Gene': 'RP11-259G18.1', 'p_SMR_multi': 5.306636e-10, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL GTEx', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.32 | Q67 | What is the top-associated SNP of the gene C12orf45 in Prefrontal Cortex eQTL omic data for FTD and is it functionally significant? | There are no SNPs within the gene C12orf45 in Prefrontal Cortex eQTL omic data that are significantly associated with FTD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "C12orf45" AND Disease = "FTD" AND LOWER(Omic_type) LIKE "%prefrontal cortex eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1220894', 'topRSID': 'rs76534636', 'Disease': 'FTD', 'Gene': 'C12orf45', 'p_SMR_multi': 0.4402121, 'p_HEIDI': 0.1049781, 'Omic_tissue': 'Prefrontal Cortex', 'Omic_type': 'Prefrontal Cortex eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.934 | Q67 | What is the top-associated SNP of the gene CSDC2 in Whole Brain meta-analysis mQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene CSDC2 in Whole Brain meta-analysis mQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CSDC2" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_224302', 'topRSID': 'rs7290991', 'Disease': 'ALS', 'Gene': 'CSDC2', 'p_SMR_multi': 0.6838046, 'p_HEIDI': 0.3733121, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_2... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.982 | Q67 | What is the top-associated SNP of the gene TMEM175 in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for TMEM175 in Whole Blood mQTL omic data for PD is rs11248059, which has a multi-SNP SMR p-value of 5.26e-11 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TMEM175" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_996283', 'topRSID': 'rs6813110', 'Disease': 'PD', 'Gene': 'TMEM175', 'p_SMR_multi': 2.618289e-11, 'p_HEIDI': 0.0001221027, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dis... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.217 | Q67 | What is the top-associated SNP of the gene APOC4 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for APOC4 in Whole Brain meta-analysis mQTL omic data for AD is rs7252480, which has a multi-SNP SMR p-value of 5.09e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "APOC4" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_122468', 'topRSID': 'rs11878597', 'Disease': 'AD', 'Gene': 'APOC4', 'p_SMR_multi': 1.942575e-13, 'p_HEIDI': 5.901231e-09, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1130 | Q67 | What is the top-associated SNP of the gene EIF3CL in Whole Blood eQTL eQTLgen omic data for FTD and is it functionally significant? | There are no SNPs within the gene EIF3CL in Whole Blood eQTL eQTLgen omic data that are significantly associated with FTD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "EIF3CL" AND Disease = "FTD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1532605', 'topRSID': 'rs10499', 'Disease': 'FTD', 'Gene': 'EIF3CL', 'p_SMR_multi': 0.7338951, 'p_HEIDI': 0.4838205, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.330 | Q67 | What is the top-associated SNP of the gene MS4A6A in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for MS4A6A in Whole Blood mQTL omic data for AD is rs1834557, which has a multi-SNP SMR p-value of 6.71e-11 and a HEIDI of 0.17, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MS4A6A" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_608694', 'topRSID': 'rs1834557', 'Disease': 'AD', 'Gene': 'MS4A6A', 'p_SMR_multi': 6.713058e-11, 'p_HEIDI': 0.1728839, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_608693', 'topRSI... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.566 | Q67 | What is the top-associated SNP of the gene CNPY4 in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for CNPY4 in Whole Blood eQTL eQTLgen omic data for AD is rs77686669, which has a multi-SNP SMR p-value of 4.83e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CNPY4" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1495794', 'topRSID': 'rs77686669', 'Disease': 'AD', 'Gene': 'CNPY4', 'p_SMR_multi': 4.834994e-10, 'p_HEIDI': 7.822272e-09, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Lin... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1112 | Q67 | What is the top-associated SNP of the gene KAT8 in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for KAT8 in Whole Blood mQTL omic data for PD is rs1978487, which has a multi-SNP SMR p-value of 1.53e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KAT8" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_974691', 'topRSID': 'rs1978487', 'Disease': 'PD', 'Gene': 'KAT8', 'p_SMR_multi': 1.533291e-08, 'p_HEIDI': 0.007315752, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequi... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.707 | Q67 | What is the top-associated SNP of the gene MAPT in Prefrontal Cortex eQTL omic data for AD and is it functionally significant? | The top-associated SNP for MAPT in Prefrontal Cortex eQTL omic data for AD is rs2532276, which has a multi-SNP SMR p-value of 2.59e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%prefrontal cortex eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1203008', 'topRSID': 'rs2532276', 'Disease': 'AD', 'Gene': 'MAPT', 'p_SMR_multi': 2.589915e-08, 'p_HEIDI': 0.0058909, 'Omic_tissue': 'Prefrontal Cortex', 'Omic_type': 'Prefrontal Cortex eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Link... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1979 | Q67 | What is the top-associated SNP of the gene BIN1 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for BIN1 in Whole Brain meta-analysis mQTL omic data for AD is rs72846701, which has a multi-SNP SMR p-value of 3.98e-15 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "BIN1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_46339', 'topRSID': 'rs730471', 'Disease': 'AD', 'Gene': 'BIN1', 'p_SMR_multi': 2.124617e-16, 'p_HEIDI': 3.050073e-22, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Li... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1189 | Q67 | What is the top-associated SNP of the gene TRIM65 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | There are no SNPs within the gene TRIM65 in Whole Brain meta-analysis mQTL omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TRIM65" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_492388', 'topRSID': 'rs59623743', 'Disease': 'PD', 'Gene': 'TRIM65', 'p_SMR_multi': 0.6015123, 'p_HEIDI': 0.856625, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_4... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.345 | Q67 | What is the top-associated SNP of the gene RP11-104H15.7 in Whole Brain meta-analysis mQTL omic data for LBD and is it functionally significant? | There are no SNPs within the gene RP11-104H15.7 in Whole Brain meta-analysis mQTL omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-104H15.7" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_394001', 'topRSID': 'rs4796305', 'Disease': 'LBD', 'Gene': 'RP11-104H15.7', 'p_SMR_multi': 0.2899221, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.636 | Q67 | What is the top-associated SNP of the gene PLK2 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | There are no SNPs within the gene PLK2 in Whole Brain meta-analysis mQTL omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PLK2" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_435572', 'topRSID': 'rs2098702', 'Disease': 'PD', 'Gene': 'PLK2', 'p_SMR_multi': 0.560005, 'p_HEIDI': 0.5436317, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_4355... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.150 | Q67 | What is the top-associated SNP of the gene APOC1 in Whole Brain meta-analysis mQTL omic data for LBD and is it functionally significant? | The top-associated SNP for APOC1 in Whole Brain meta-analysis mQTL omic data for LBD is rs10414043, which has a multi-SNP SMR p-value of 5.53e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "APOC1" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_402975', 'topRSID': 'rs10414043', 'Disease': 'LBD', 'Gene': 'APOC1', 'p_SMR_multi': 5.527557e-08, 'p_HEIDI': 0.001037341, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1197 | Q67 | What is the top-associated SNP of the gene MTCH2 in Whole Brain eQTL omic data for AD and is it functionally significant? | The top-associated SNP for MTCH2 in Whole Brain eQTL omic data for AD is rs17788853, which has a multi-SNP SMR p-value of 8.06e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MTCH2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1609002', 'topRSID': 'rs17788853', 'Disease': 'AD', 'Gene': 'MTCH2', 'p_SMR_multi': 8.057016e-08, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequil... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.365 | Q67 | What is the top-associated SNP of the gene KANSL1-AS1 in Cerebellar Hemisphere eQTL omic data for PD and is it functionally significant? | The top-associated SNP for KANSL1-AS1 in Cerebellar Hemisphere eQTL omic data for PD is rs55974014, which has a multi-SNP SMR p-value of 7.96e-12 and a HEIDI of 0.2, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1-AS1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cerebellar hemisphere eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1191172', 'topRSID': 'rs55974014', 'Disease': 'PD', 'Gene': 'KANSL1-AS1', 'p_SMR_multi': 7.957344e-12, 'p_HEIDI': 0.1977533, 'Omic_tissue': 'Cerebellar Hemisphere', 'Omic_type': 'Cerebellar Hemisphere eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.86 | Q67 | What is the top-associated SNP of the gene ARHGAP27 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for ARHGAP27 in Whole Brain meta-analysis mQTL omic data for PD is rs1230106, which has a multi-SNP SMR p-value of 4.52e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARHGAP27" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_491057', 'topRSID': 'rs62065376', 'Disease': 'PD', 'Gene': 'ARHGAP27', 'p_SMR_multi': 1.134698e-11, 'p_HEIDI': 0.3072466, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.49 | Q67 | What is the top-associated SNP of the gene WDR18 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD and is it functionally significant? | The top-associated SNP for WDR18 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD is rs2240149, which has a multi-SNP SMR p-value of 4.87e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "WDR18" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1397178', 'topRSID': 'rs2240149', 'Disease': 'AD', 'Gene': 'WDR18', 'p_SMR_multi': 4.865151e-07, 'p_HEIDI': 0.001081871, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'association meets significance thresho... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.474 | Q67 | What is the top-associated SNP of the gene SETD1A in Whole Blood eQTL eQTLgen omic data for PD and is it functionally significant? | The top-associated SNP for SETD1A in Whole Blood eQTL eQTLgen omic data for PD is rs7206511, which has a multi-SNP SMR p-value of 7.31e-09 and a HEIDI of 0.43, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SETD1A" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1563807', 'topRSID': 'rs7206511', 'Disease': 'PD', 'Gene': 'SETD1A', 'p_SMR_multi': 7.308286e-09, 'p_HEIDI': 0.4254096, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.158 | Q67 | What is the top-associated SNP of the gene PLAC9 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for PLAC9 in Whole Blood mQTL omic data for AD is rs745182, which has a multi-SNP SMR p-value of 1.90e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PLAC9" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_572609', 'topRSID': 'rs745182', 'Disease': 'AD', 'Gene': 'PLAC9', 'p_SMR_multi': 1.896037e-07, 'p_HEIDI': 0.0007834608, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.764 | Q67 | What is the top-associated SNP of the gene CNPY4 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD and is it functionally significant? | The top-associated SNP for CNPY4 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD is rs7457787, which has a multi-SNP SMR p-value of 8.33e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CNPY4" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1392619', 'topRSID': 'rs7457787', 'Disease': 'AD', 'Gene': 'CNPY4', 'p_SMR_multi': 8.325836e-08, 'p_HEIDI': 4.508875e-08, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'association meets significance thresh... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1027 | Q67 | What is the top-associated SNP of the gene WNT8B in Whole Brain meta-analysis mQTL omic data for FTD and is it functionally significant? | There are no SNPs within the gene WNT8B in Whole Brain meta-analysis mQTL omic data that are significantly associated with FTD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "WNT8B" AND Disease = "FTD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_275331', 'topRSID': 'rs12355721', 'Disease': 'FTD', 'Gene': 'WNT8B', 'p_SMR_multi': 0.5403124, 'p_HEIDI': 0.869435, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_2... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1200 | Q67 | What is the top-associated SNP of the gene EAPP in Whole Brain meta-analysis mQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene EAPP in Whole Brain meta-analysis mQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "EAPP" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_197957', 'topRSID': 'rs28451576', 'Disease': 'ALS', 'Gene': 'EAPP', 'p_SMR_multi': 0.8487775, 'p_HEIDI': 0.6284674, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_1... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1404 | Q67 | What is the top-associated SNP of the gene RIN3 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD and is it functionally significant? | The top-associated SNP for RIN3 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD is rs4904944, which has a multi-SNP SMR p-value of 1.23e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RIN3" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1395551', 'topRSID': 'rs4904944', 'Disease': 'AD', 'Gene': 'RIN3', 'p_SMR_multi': 1.23213e-06, 'p_HEIDI': 4.214218e-07, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'association meets significance threshol... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1202 | Q67 | What is the top-associated SNP of the gene SNCA in Whole Blood mQTL omic data for LBD and is it functionally significant? | The top-associated SNP for SNCA in Whole Blood mQTL omic data for LBD is rs1372520, which has a multi-SNP SMR p-value of 2.67e-09 and a HEIDI of 0.05, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SNCA" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_934862', 'topRSID': 'rs2301134', 'Disease': 'LBD', 'Gene': 'SNCA', 'p_SMR_multi': 3.123872e-10, 'p_HEIDI': 0.8604982, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_934864', 'topRSID... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1631 | Q67 | What is the top-associated SNP of the gene PRSS36 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD and is it functionally significant? | The top-associated SNP for PRSS36 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD is rs78924645, which has a multi-SNP SMR p-value of 2.10e-06 and a HEIDI of 0.01, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PRSS36" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1396182', 'topRSID': 'rs78924645', 'Disease': 'AD', 'Gene': 'PRSS36', 'p_SMR_multi': 2.103277e-06, 'p_HEIDI': 0.0123253, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
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