uuid stringlengths 4 8 | template_uuid stringclasses 40
values | question stringlengths 13 193 | answer stringlengths 29 2.2k | benchmark_query stringlengths 133 622 | execution_results stringlengths 2 1.14M | query_type stringclasses 2
values | sql_category stringclasses 26
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|---|---|---|---|---|---|---|---|---|
Q67.44 | Q67 | What is the top-associated SNP of the gene SORBS3 in Whole Blood mQTL omic data for PD and is it functionally significant? | There are no SNPs within the gene SORBS3 in Whole Blood mQTL omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SORBS3" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_985958', 'topRSID': 'rs17733242', 'Disease': 'PD', 'Gene': 'SORBS3', 'p_SMR_multi': 0.002500994, 'p_HEIDI': 0.3310329, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_985959', 'to... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.278 | Q67 | What is the top-associated SNP of the gene MAPT in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for MAPT in Whole Brain meta-analysis mQTL omic data for PD is rs62063779, which has a multi-SNP SMR p-value of 2.17e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_491114', 'topRSID': 'rs17652121', 'Disease': 'PD', 'Gene': 'MAPT', 'p_SMR_multi': 4.729064e-14, 'p_HEIDI': 0.04416005, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_49... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1096 | Q67 | What is the top-associated SNP of the gene RP11-333E1.1 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for RP11-333E1.1 in Whole Blood mQTL omic data for AD is rs112809920, which has a multi-SNP SMR p-value of 9.95e-07 and a HEIDI of 0.43, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-333E1.1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_589057', 'topRSID': 'rs112918260', 'Disease': 'AD', 'Gene': 'RP11-333E1.1', 'p_SMR_multi': 4.791144e-08, 'p_HEIDI': 0.2742732, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_589056',... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.104 | Q67 | What is the top-associated SNP of the gene LRRC37A2 in Hippocampus eQTL omic data for PD and is it functionally significant? | The top-associated SNP for LRRC37A2 in Hippocampus eQTL omic data for PD is rs2942166, which has a multi-SNP SMR p-value of 1.43e-11 and a HEIDI of 0.32, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A2" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%hippocampus eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1386997', 'topRSID': 'rs2942166', 'Disease': 'PD', 'Gene': 'LRRC37A2', 'p_SMR_multi': 1.427218e-11, 'p_HEIDI': 0.3236888, 'Omic_tissue': 'Hippocampus', 'Omic_type': 'Hippocampus eQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_33017', 'topR... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.856 | Q67 | What is the top-associated SNP of the gene ADCY10P1 in Tibial Nerve eQTL omic data for AD and is it functionally significant? | The top-associated SNP for ADCY10P1 in Tibial Nerve eQTL omic data for AD is rs72856298, which has a multi-SNP SMR p-value of 3.50e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ADCY10P1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%tibial nerve eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1287225', 'topRSID': 'rs72856298', 'Disease': 'AD', 'Gene': 'ADCY10P1', 'p_SMR_multi': 3.498401e-07, 'p_HEIDI': 1.266494e-07, 'Omic_tissue': 'Tibial Nerve', 'Omic_type': 'Tibial Nerve eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkag... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.985 | Q67 | What is the top-associated SNP of the gene LRRC37A4P in Substantia nigra eQTL omic data for PD and is it functionally significant? | The top-associated SNP for LRRC37A4P in Substantia nigra eQTL omic data for PD is rs58879558, which has a multi-SNP SMR p-value of 2.72e-11 and a HEIDI of 0.13, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A4P" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%substantia nigra eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1451658', 'topRSID': 'rs58879558', 'Disease': 'PD', 'Gene': 'LRRC37A4P', 'p_SMR_multi': 2.717363e-11, 'p_HEIDI': 0.131708, 'Omic_tissue': 'Substantia nigra', 'Omic_type': 'Substantia nigra eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.948 | Q67 | What is the top-associated SNP of the gene EPHX2 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for EPHX2 in Whole Brain meta-analysis mQTL omic data for AD is rs10096092, which has a multi-SNP SMR p-value of 1.25e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "EPHX2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_78248', 'topRSID': 'rs73227337', 'Disease': 'AD', 'Gene': 'EPHX2', 'p_SMR_multi': 1.500668e-09, 'p_HEIDI': 0.01595741, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_78... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.110 | Q67 | What is the top-associated SNP of the gene MVP in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for MVP in Whole Blood mQTL omic data for AD is rs12920760, which has a multi-SNP SMR p-value of 4.84e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MVP" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_577401', 'topRSID': 'rs12920760', 'Disease': 'AD', 'Gene': 'MVP', 'p_SMR_multi': 4.844785e-08, 'p_HEIDI': 2.80169e-05, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequi... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1296 | Q67 | What is the top-associated SNP of the gene RP11-259G18.2 in Amygdala eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for RP11-259G18.2 in Amygdala eQTL omic data for PSP is rs169201, which has a multi-SNP SMR p-value of 1.89e-14 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.2" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%amygdala eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1604714', 'topRSID': 'rs169201', 'Disease': 'PSP', 'Gene': 'RP11-259G18.2', 'p_SMR_multi': 1.88641e-14, 'p_HEIDI': 2.761821e-11, 'Omic_tissue': 'Amygdala', 'Omic_type': 'Amygdala eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dis... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.503 | Q67 | What is the top-associated SNP of the gene CLU in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for CLU in Whole Brain meta-analysis mQTL omic data for AD is rs7982, which has a multi-SNP SMR p-value of 2.50e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CLU" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_78262', 'topRSID': 'rs7982', 'Disease': 'AD', 'Gene': 'CLU', 'p_SMR_multi': 2.501744e-10, 'p_HEIDI': 6.84878e-05, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkag... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1981 | Q67 | What is the top-associated SNP of the gene FCER1G in Whole Blood eQTL GTEx omic data for AD and is it functionally significant? | The top-associated SNP for FCER1G in Whole Blood eQTL GTEx omic data for AD is rs2070901, which has a multi-SNP SMR p-value of 1.13e-06 and a HEIDI of 0.09, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "FCER1G" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1647531', 'topRSID': 'rs2070901', 'Disease': 'AD', 'Gene': 'FCER1G', 'p_SMR_multi': 1.125342e-06, 'p_HEIDI': 0.08890531, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL GTEx', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.869 | Q67 | What is the top-associated SNP of the gene ARHGAP27 in Whole Brain meta-analysis mQTL omic data for PSP and is it functionally significant? | The top-associated SNP for ARHGAP27 in Whole Brain meta-analysis mQTL omic data for PSP is rs11012, which has a multi-SNP SMR p-value of 7.46e-11 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARHGAP27" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_560834', 'topRSID': 'rs11012', 'Disease': 'PSP', 'Gene': 'ARHGAP27', 'p_SMR_multi': 9.282341e-28, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Li... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.748 | Q67 | What is the top-associated SNP of the gene LRRC37A2 in Liver eQTL omic data for PD and is it functionally significant? | The top-associated SNP for LRRC37A2 in Liver eQTL omic data for PD is rs58879558, which has a multi-SNP SMR p-value of 1.24e-10 and a HEIDI of 0.47, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A2" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%liver eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1476433', 'topRSID': 'rs58879558', 'Disease': 'PD', 'Gene': 'LRRC37A2', 'p_SMR_multi': 1.244528e-10, 'p_HEIDI': 0.4735931, 'Omic_tissue': 'Liver', 'Omic_type': 'Liver eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1015 | Q67 | What is the top-associated SNP of the gene ARL17A in Whole Brain eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for ARL17A in Whole Brain eQTL omic data for PSP is rs11012, which has a multi-SNP SMR p-value of 3.70e-14 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARL17A" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole brain eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1646051', 'topRSID': 'rs11012', 'Disease': 'PSP', 'Gene': 'ARL17A', 'p_SMR_multi': 3.695756e-14, 'p_HEIDI': 2.698306e-19, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dise... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1315 | Q67 | What is the top-associated SNP of the gene APOC1 in Whole Blood mQTL omic data for LBD and is it functionally significant? | The top-associated SNP for APOC1 in Whole Blood mQTL omic data for LBD is rs59325138, which has a multi-SNP SMR p-value of 1.12e-06 and a HEIDI of 0.02, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "APOC1" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_928300', 'topRSID': 'rs59325138', 'Disease': 'LBD', 'Gene': 'APOC1', 'p_SMR_multi': 1.122469e-06, 'p_HEIDI': 0.01802146, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_928301', 'topR... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1297 | Q67 | What is the top-associated SNP of the gene HCG27 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for HCG27 in Whole Blood mQTL omic data for AD is rs1265098, which has a multi-SNP SMR p-value of 9.02e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "HCG27" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_620835', 'topRSID': 'rs1265098', 'Disease': 'AD', 'Gene': 'HCG27', 'p_SMR_multi': 9.024084e-07, 'p_HEIDI': 0.007768795, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.609 | Q67 | What is the top-associated SNP of the gene DND1P1 in Caudate Basal Ganglia eQTL omic data for PD and is it functionally significant? | The top-associated SNP for DND1P1 in Caudate Basal Ganglia eQTL omic data for PD is rs55974014, which has a multi-SNP SMR p-value of 4.75e-11 and a HEIDI of 0.87, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "DND1P1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%caudate basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1281350', 'topRSID': 'rs55974014', 'Disease': 'PD', 'Gene': 'DND1P1', 'p_SMR_multi': 4.749159e-11, 'p_HEIDI': 0.8706195, 'Omic_tissue': 'Caudate Basal Ganglia', 'Omic_type': 'Caudate Basal Ganglia eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1362 | Q67 | What is the top-associated SNP of the gene WNT3 in Whole Brain eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for WNT3 in Whole Brain eQTL omic data for PSP is rs12952746, which has a multi-SNP SMR p-value of 1.31e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "WNT3" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole brain eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1646053', 'topRSID': 'rs12952746', 'Disease': 'PSP', 'Gene': 'WNT3', 'p_SMR_multi': 1.306315e-10, 'p_HEIDI': 8.383191e-07, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dis... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.75 | Q67 | What is the top-associated SNP of the gene CD2AP in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for CD2AP in Whole Brain meta-analysis mQTL omic data for AD is rs7738044, which has a multi-SNP SMR p-value of 6.50e-08 and a HEIDI of 0.1, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CD2AP" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_67374', 'topRSID': 'rs7738044', 'Disease': 'AD', 'Gene': 'CD2AP', 'p_SMR_multi': 6.498931e-08, 'p_HEIDI': 0.1048021, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_6737... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1082 | Q67 | What is the top-associated SNP of the gene RP11-669E14.4 in Liver eQTL omic data for AD and is it functionally significant? | The top-associated SNP for RP11-669E14.4 in Liver eQTL omic data for AD is rs17661027, which has a multi-SNP SMR p-value of 2.36e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-669E14.4" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%liver eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1466644', 'topRSID': 'rs17661027', 'Disease': 'AD', 'Gene': 'RP11-669E14.4', 'p_SMR_multi': 2.358863e-06, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Liver', 'Omic_type': 'Liver eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequilibri... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1214 | Q67 | What is the top-associated SNP of the gene GPR78 in Whole Blood mQTL omic data for PD and is it functionally significant? | There are no SNPs within the gene GPR78 in Whole Blood mQTL omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "GPR78" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_997481', 'topRSID': 'rs73213381', 'Disease': 'PD', 'Gene': 'GPR78', 'p_SMR_multi': 0.2573387, 'p_HEIDI': 0.07924717, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_997482', 'topR... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1167 | Q67 | What is the top-associated SNP of the gene SNCA in Whole Brain meta-analysis mQTL omic data for LBD and is it functionally significant? | The top-associated SNP for SNCA in Whole Brain meta-analysis mQTL omic data for LBD is rs1372520, which has a multi-SNP SMR p-value of 3.80e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SNCA" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_338827', 'topRSID': 'rs3756059', 'Disease': 'LBD', 'Gene': 'SNCA', 'p_SMR_multi': 4.824404e-10, 'p_HEIDI': 0.0002321407, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.625 | Q67 | What is the top-associated SNP of the gene MAPT-AS1 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for MAPT-AS1 in Whole Brain meta-analysis mQTL omic data for PD is rs62063845, which has a multi-SNP SMR p-value of 1.18e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT-AS1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_491096', 'topRSID': 'rs56280951', 'Disease': 'PD', 'Gene': 'MAPT-AS1', 'p_SMR_multi': 3.97087e-15, 'p_HEIDI': 0.001150121, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkag... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.487 | Q67 | What is the top-associated SNP of the gene VKORC1 in Liver eQTL omic data for PD and is it functionally significant? | The top-associated SNP for VKORC1 in Liver eQTL omic data for PD is rs9923231, which has a multi-SNP SMR p-value of 2.75e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "VKORC1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%liver eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1476296', 'topRSID': 'rs9923231', 'Disease': 'PD', 'Gene': 'VKORC1', 'p_SMR_multi': 2.746395e-08, 'p_HEIDI': 0.001518397, 'Omic_tissue': 'Liver', 'Omic_type': 'Liver eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium'}... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1579 | Q67 | What is the top-associated SNP of the gene RP11-259G18.3 in Liver eQTL omic data for PD and is it functionally significant? | The top-associated SNP for RP11-259G18.3 in Liver eQTL omic data for PD is rs9468, which has a multi-SNP SMR p-value of 7.61e-13 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.3" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%liver eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1476429', 'topRSID': 'rs9468', 'Disease': 'PD', 'Gene': 'RP11-259G18.3', 'p_SMR_multi': 7.605082e-13, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Liver', 'Omic_type': 'Liver eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium'}... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.512 | Q67 | What is the top-associated SNP of the gene C9orf72 in Hippocampus eQTL omic data for ALS and is it functionally significant? | The top-associated SNP for C9orf72 in Hippocampus eQTL omic data for ALS is rs1031153, which has a multi-SNP SMR p-value of 3.52e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "C9orf72" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%hippocampus eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1379984', 'topRSID': 'rs1031153', 'Disease': 'ALS', 'Gene': 'C9orf72', 'p_SMR_multi': 3.520575e-07, 'p_HEIDI': 0.005113277, 'Omic_tissue': 'Hippocampus', 'Omic_type': 'Hippocampus eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Di... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.740 | Q67 | What is the top-associated SNP of the gene BTNL2 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for BTNL2 in Whole Blood mQTL omic data for AD is rs28366340, which has a multi-SNP SMR p-value of 8.59e-07 and a HEIDI of 0.34, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "BTNL2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_621688', 'topRSID': 'rs116522341', 'Disease': 'AD', 'Gene': 'BTNL2', 'p_SMR_multi': 2.681311e-09, 'p_HEIDI': 2.28461e-05, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dise... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.762 | Q67 | What is the top-associated SNP of the gene MAPT in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for MAPT in Whole Blood mQTL omic data for AD is rs17689882, which has a multi-SNP SMR p-value of 2.53e-07 and a HEIDI of 0.03, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_591203', 'topRSID': 'rs17689882', 'Disease': 'AD', 'Gene': 'MAPT', 'p_SMR_multi': 2.532079e-07, 'p_HEIDI': 0.02723276, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_591210', 'topRSI... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1990 | Q67 | What is the top-associated SNP of the gene KANSL1 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for KANSL1 in Whole Brain meta-analysis mQTL omic data for PD is rs1966345, which has a multi-SNP SMR p-value of 2.28e-19 and a HEIDI of 0.07, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_491139', 'topRSID': 'rs12150087', 'Disease': 'PD', 'Gene': 'KANSL1', 'p_SMR_multi': 8.107128999999999e-20, 'p_HEIDI': 0.009069932, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs o... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.784 | Q67 | What is the top-associated SNP of the gene C17orf107 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for C17orf107 in Whole Blood mQTL omic data for AD is rs72835064, which has a multi-SNP SMR p-value of 1.36e-06 and a HEIDI of 0.02, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "C17orf107" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_589015', 'topRSID': 'rs16954243', 'Disease': 'AD', 'Gene': 'C17orf107', 'p_SMR_multi': 3.798115e-07, 'p_HEIDI': 0.008150263, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage D... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1763 | Q67 | What is the top-associated SNP of the gene STAG3 in Cerebellar Hemisphere eQTL omic data for AD and is it functionally significant? | The top-associated SNP for STAG3 in Cerebellar Hemisphere eQTL omic data for AD is rs34130487, which has a multi-SNP SMR p-value of 2.88e-07 and a HEIDI of 0.53, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "STAG3" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%cerebellar hemisphere eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1172873', 'topRSID': 'rs34130487', 'Disease': 'AD', 'Gene': 'STAG3', 'p_SMR_multi': 2.876461e-07, 'p_HEIDI': 0.5273926, 'Omic_tissue': 'Cerebellar Hemisphere', 'Omic_type': 'Cerebellar Hemisphere eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.848 | Q67 | What is the top-associated SNP of the gene BIN1 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for BIN1 in Whole Brain meta-analysis mQTL omic data for AD is rs1060743, which has a multi-SNP SMR p-value of 3.30e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "BIN1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_46339', 'topRSID': 'rs730471', 'Disease': 'AD', 'Gene': 'BIN1', 'p_SMR_multi': 2.124617e-16, 'p_HEIDI': 3.050073e-22, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Li... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.315 | Q67 | What is the top-associated SNP of the gene PACRGL in Cerebellum eQTL omic data for AD and is it functionally significant? | There are no SNPs within the gene PACRGL in Cerebellum eQTL omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PACRGL" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_770', 'topRSID': 'rs11726872', 'Disease': 'AD', 'Gene': 'PACRGL', 'p_SMR_multi': 0.3953311, 'p_HEIDI': 0.6837036, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_1687078', 'topRSID'... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.816 | Q67 | What is the top-associated SNP of the gene CD300LF in Tibial Nerve eQTL omic data for PSP and is it functionally significant? | There are no SNPs within the gene CD300LF in Tibial Nerve eQTL omic data that are significantly associated with PSP, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CD300LF" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%tibial nerve eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1336398', 'topRSID': 'rs2034310', 'Disease': 'PSP', 'Gene': 'CD300LF', 'p_SMR_multi': 0.09111759, 'p_HEIDI': 0.4332115, 'Omic_tissue': 'Tibial Nerve', 'Omic_type': 'Tibial Nerve eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.411 | Q67 | What is the top-associated SNP of the gene ARHGAP27 in Whole Brain meta-analysis mQTL omic data for PSP and is it functionally significant? | The top-associated SNP for ARHGAP27 in Whole Brain meta-analysis mQTL omic data for PSP is rs11012, which has a multi-SNP SMR p-value of 7.44e-15 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARHGAP27" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_560834', 'topRSID': 'rs11012', 'Disease': 'PSP', 'Gene': 'ARHGAP27', 'p_SMR_multi': 9.282341e-28, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Li... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.826 | Q67 | What is the top-associated SNP of the gene KANSL1 in Cerebellum eQTL omic data for PD and is it functionally significant? | The top-associated SNP for KANSL1 in Cerebellum eQTL omic data for PD is rs112995313, which has a multi-SNP SMR p-value of 2.19e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_19647', 'topRSID': 'rs112995313', 'Disease': 'PD', 'Gene': 'KANSL1', 'p_SMR_multi': 2.193847e-10, 'p_HEIDI': 8.102405e-06, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1143 | Q67 | What is the top-associated SNP of the gene TAP2 in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for TAP2 in Whole Blood eQTL eQTLgen omic data for AD is rs4148876, which has a multi-SNP SMR p-value of 9.94e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TAP2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1494776', 'topRSID': 'rs4148876', 'Disease': 'AD', 'Gene': 'TAP2', 'p_SMR_multi': 9.936974e-08, 'p_HEIDI': 0.0001713229, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linka... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.313 | Q67 | What is the top-associated SNP of the gene LRRC37A4P in Cerebellum eQTL omic data for AD and is it functionally significant? | The top-associated SNP for LRRC37A4P in Cerebellum eQTL omic data for AD is rs1991556, which has a multi-SNP SMR p-value of 2.22e-06 and a HEIDI of 0.95, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A4P" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1690038', 'topRSID': 'rs1991556', 'Disease': 'AD', 'Gene': 'LRRC37A4P', 'p_SMR_multi': 2.216345e-06, 'p_HEIDI': 0.9510566, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.229 | Q67 | What is the top-associated SNP of the gene ANXA11 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for ANXA11 in Whole Blood mQTL omic data for AD is rs2819950, which has a multi-SNP SMR p-value of 8.58e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ANXA11" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_572615', 'topRSID': 'rs2819950', 'Disease': 'AD', 'Gene': 'ANXA11', 'p_SMR_multi': 8.583903e-08, 'p_HEIDI': 0.001441165, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1699 | Q67 | What is the top-associated SNP of the gene DND1P1 in Amygdala eQTL omic data for PD and is it functionally significant? | The top-associated SNP for DND1P1 in Amygdala eQTL omic data for PD is rs55974014, which has a multi-SNP SMR p-value of 2.72e-09 and a HEIDI of 0.51, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "DND1P1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%amygdala eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1603773', 'topRSID': 'rs55974014', 'Disease': 'PD', 'Gene': 'DND1P1', 'p_SMR_multi': 2.717583e-09, 'p_HEIDI': 0.5077181, 'Omic_tissue': 'Amygdala', 'Omic_type': 'Amygdala eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1451 | Q67 | What is the top-associated SNP of the gene SPTB in Whole Blood mQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene SPTB in Whole Blood mQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SPTB" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_713939', 'topRSID': 'rs170679', 'Disease': 'ALS', 'Gene': 'SPTB', 'p_SMR_multi': 0.1991775, 'p_HEIDI': 0.3752685, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_713948', 'topRSID... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1976 | Q67 | What is the top-associated SNP of the gene FNBP4 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for FNBP4 in Whole Blood mQTL omic data for AD is rs12807014, which has a multi-SNP SMR p-value of 1.16e-06 and a HEIDI of 0.03, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "FNBP4" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_608507', 'topRSID': 'rs12807014', 'Disease': 'AD', 'Gene': 'FNBP4', 'p_SMR_multi': 1.162814e-06, 'p_HEIDI': 0.03212485, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_608506', 'topRS... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.814 | Q67 | What is the top-associated SNP of the gene KANSL1 in Whole Blood eQTL GTEx omic data for PSP and is it functionally significant? | The top-associated SNP for KANSL1 in Whole Blood eQTL GTEx omic data for PSP is rs17692129, which has a multi-SNP SMR p-value of 2.15e-17 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1684934', 'topRSID': 'rs17692129', 'Disease': 'PSP', 'Gene': 'KANSL1', 'p_SMR_multi': 2.1495340000000002e-17, 'p_HEIDI': 2.57845e-10, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL GTEx', 'func_sig': 'association meets significance threshold but shows signs of link... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1847 | Q67 | What is the top-associated SNP of the gene ARL17A in Whole Brain eQTL omic data for PD and is it functionally significant? | The top-associated SNP for ARL17A in Whole Brain eQTL omic data for PD is rs35732828, which has a multi-SNP SMR p-value of 1.35e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARL17A" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1640230', 'topRSID': 'rs35732828', 'Disease': 'PD', 'Gene': 'ARL17A', 'p_SMR_multi': 1.347916e-09, 'p_HEIDI': 1.598166e-09, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Di... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.151 | Q67 | What is the top-associated SNP of the gene MAPT in Whole Brain meta-analysis mQTL omic data for PSP and is it functionally significant? | The top-associated SNP for MAPT in Whole Brain meta-analysis mQTL omic data for PSP is rs8070723, which has a multi-SNP SMR p-value of 1.36e-34 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_560864', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'MAPT', 'p_SMR_multi': 2.100115e-44, 'p_HEIDI': 0.01425494, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_56... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.781 | Q67 | What is the top-associated SNP of the gene DOC2A in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for DOC2A in Whole Blood mQTL omic data for AD is rs11649149, which has a multi-SNP SMR p-value of 5.92e-07 and a HEIDI of 0.15, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "DOC2A" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_577418', 'topRSID': 'rs12921753', 'Disease': 'AD', 'Gene': 'DOC2A', 'p_SMR_multi': 5.575261e-12, 'p_HEIDI': 0.3441697, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_577427', 'topRSI... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.727 | Q67 | What is the top-associated SNP of the gene PVRL2 in Skeletal Muscle eQTL omic data for AD and is it functionally significant? | The top-associated SNP for PVRL2 in Skeletal Muscle eQTL omic data for AD is rs3810143, which has a multi-SNP SMR p-value of 6.92e-12 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PVRL2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%skeletal muscle eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1343794', 'topRSID': 'rs3810143', 'Disease': 'AD', 'Gene': 'PVRL2', 'p_SMR_multi': 6.915125e-12, 'p_HEIDI': 2.872884e-13, 'Omic_tissue': 'Skeletal Muscle', 'Omic_type': 'Skeletal Muscle eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Link... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.820 | Q67 | What is the top-associated SNP of the gene SSRP1 in Whole Brain eQTL omic data for AD and is it functionally significant? | There are no SNPs within the gene SSRP1 in Whole Brain eQTL omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SSRP1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1609008', 'topRSID': 'rs6591426', 'Disease': 'AD', 'Gene': 'SSRP1', 'p_SMR_multi': 0.8994447, 'p_HEIDI': 0.4923376, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1636 | Q67 | What is the top-associated SNP of the gene MMRN1 in Liver eQTL omic data for PD and is it functionally significant? | The top-associated SNP for MMRN1 in Liver eQTL omic data for PD is rs1866995, which has a multi-SNP SMR p-value of 1.04e-06 and a HEIDI of 0.04, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MMRN1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%liver eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1475008', 'topRSID': 'rs1866995', 'Disease': 'PD', 'Gene': 'MMRN1', 'p_SMR_multi': 1.038552e-06, 'p_HEIDI': 0.04416156, 'Omic_tissue': 'Liver', 'Omic_type': 'Liver eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.825 | Q67 | What is the top-associated SNP of the gene GAK in Whole Blood mQTL omic data for PSP and is it functionally significant? | There are no SNPs within the gene GAK in Whole Blood mQTL omic data that are significantly associated with PSP, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "GAK" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1068721', 'topRSID': 'rs11248060', 'Disease': 'PSP', 'Gene': 'GAK', 'p_SMR_multi': 0.04998859, 'p_HEIDI': 0.9886678, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_1068724', 'top... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.581 | Q67 | What is the top-associated SNP of the gene YPEL3 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for YPEL3 in Whole Blood mQTL omic data for AD is rs7201518, which has a multi-SNP SMR p-value of 4.37e-07 and a HEIDI of 0.09, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "YPEL3" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_577437', 'topRSID': 'rs7201518', 'Disease': 'AD', 'Gene': 'YPEL3', 'p_SMR_multi': 4.369101e-07, 'p_HEIDI': 0.08676983, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_577439', 'topRSI... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.563 | Q67 | What is the top-associated SNP of the gene RP11-259G18.3 in Substantia nigra eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for RP11-259G18.3 in Substantia nigra eQTL omic data for PSP is rs169201, which has a multi-SNP SMR p-value of 7.58e-11 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.3" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%substantia nigra eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1452484', 'topRSID': 'rs169201', 'Disease': 'PSP', 'Gene': 'RP11-259G18.3', 'p_SMR_multi': 7.584953e-11, 'p_HEIDI': 1.473435e-05, 'Omic_tissue': 'Substantia nigra', 'Omic_type': 'Substantia nigra eQTL', 'func_sig': 'association meets significance threshold but shows signs of lin... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1758 | Q67 | What is the top-associated SNP of the gene NELFB in Nucleus Accumbens Basal Ganglia omic data for LBD and is it functionally significant? | There are no SNPs within the gene NELFB in Nucleus Accumbens Basal Ganglia omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "NELFB" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%nucleus accumbens basal ganglia%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1725899', 'topRSID': 'rs13297305', 'Disease': 'LBD', 'Gene': 'NELFB', 'p_SMR_multi': 0.9110663, 'p_HEIDI': 0.7323618, 'Omic_tissue': 'Nucleus Accumbens Basal', 'Omic_type': 'Nucleus Accumbens Basal Ganglia', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1727 | Q67 | What is the top-associated SNP of the gene CCNA1 in Whole Blood mQTL omic data for PSP and is it functionally significant? | There are no SNPs within the gene CCNA1 in Whole Blood mQTL omic data that are significantly associated with PSP, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CCNA1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1097176', 'topRSID': 'rs4941837', 'Disease': 'PSP', 'Gene': 'CCNA1', 'p_SMR_multi': 0.5287758, 'p_HEIDI': 0.4049589, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_1097180', 'top... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1349 | Q67 | What is the top-associated SNP of the gene ARL17A in Putamen Basal Ganglia eQTL omic data for PD and is it functionally significant? | The top-associated SNP for ARL17A in Putamen Basal Ganglia eQTL omic data for PD is rs757055, which has a multi-SNP SMR p-value of 4.34e-08 and a HEIDI of 0.65, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARL17A" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%putamen basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1594932', 'topRSID': 'rs757055', 'Disease': 'PD', 'Gene': 'ARL17A', 'p_SMR_multi': 4.337545e-08, 'p_HEIDI': 0.6514905, 'Omic_tissue': 'Putamen Basal Ganglia', 'Omic_type': 'Putamen Basal Ganglia eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1161 | Q67 | What is the top-associated SNP of the gene APOC4 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for APOC4 in Whole Blood mQTL omic data for AD is rs204482, which has a multi-SNP SMR p-value of 5.99e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "APOC4" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_637435', 'topRSID': 'rs5120', 'Disease': 'AD', 'Gene': 'APOC4', 'p_SMR_multi': 3.09724e-20, 'p_HEIDI': 3.551854e-17, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequili... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.945 | Q67 | What is the top-associated SNP of the gene DND1P1 in Cerebellum eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for DND1P1 in Cerebellum eQTL omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 3.09e-12 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "DND1P1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1714151', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'DND1P1', 'p_SMR_multi': 3.090669e-12, 'p_HEIDI': 8.416991e-12, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dise... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.290 | Q67 | What is the top-associated SNP of the gene C19orf6 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for C19orf6 in Whole Blood mQTL omic data for AD is rs4807395, which has a multi-SNP SMR p-value of 1.49e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "C19orf6" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_634274', 'topRSID': 'rs4807395', 'Disease': 'AD', 'Gene': 'C19orf6', 'p_SMR_multi': 1.492903e-06, 'p_HEIDI': 0.0003908802, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dis... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1947 | Q67 | What is the top-associated SNP of the gene POLR2E in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD and is it functionally significant? | The top-associated SNP for POLR2E in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD is rs6843, which has a multi-SNP SMR p-value of 5.17e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "POLR2E" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1397183', 'topRSID': 'rs6843', 'Disease': 'AD', 'Gene': 'POLR2E', 'p_SMR_multi': 5.172203e-10, 'p_HEIDI': 0.0001171661, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'association meets significance threshol... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.973 | Q67 | What is the top-associated SNP of the gene C9orf72 in Caudate Basal Ganglia eQTL omic data for ALS and is it functionally significant? | The top-associated SNP for C9orf72 in Caudate Basal Ganglia eQTL omic data for ALS is rs774358, which has a multi-SNP SMR p-value of 2.94e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "C9orf72" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%caudate basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1270356', 'topRSID': 'rs774358', 'Disease': 'ALS', 'Gene': 'C9orf72', 'p_SMR_multi': 2.939078e-08, 'p_HEIDI': 0.007895794, 'Omic_tissue': 'Caudate Basal Ganglia', 'Omic_type': 'Caudate Basal Ganglia eQTL', 'func_sig': 'association meets significance threshold but shows signs of ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.605 | Q67 | What is the top-associated SNP of the gene STK39 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for STK39 in Whole Brain meta-analysis mQTL omic data for PD is rs2390669, which has a multi-SNP SMR p-value of 1.17e-07 and a HEIDI of 0.46, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "STK39" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_422838', 'topRSID': 'rs2390669', 'Disease': 'PD', 'Gene': 'STK39', 'p_SMR_multi': 1.174594e-07, 'p_HEIDI': 0.4649286, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_422... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1312 | Q67 | What is the top-associated SNP of the gene CCDC3 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | There are no SNPs within the gene CCDC3 in Whole Brain meta-analysis mQTL omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CCDC3" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_84104', 'topRSID': 'rs633842', 'Disease': 'AD', 'Gene': 'CCDC3', 'p_SMR_multi': 0.190698, 'p_HEIDI': 0.02989859, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_8410... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1244 | Q67 | What is the top-associated SNP of the gene C6orf10 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for C6orf10 in Whole Blood mQTL omic data for AD is rs35265698, which has a multi-SNP SMR p-value of 1.82e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "C6orf10" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_621662', 'topRSID': 'rs35265698', 'Disease': 'AD', 'Gene': 'C6orf10', 'p_SMR_multi': 2.929935e-08, 'p_HEIDI': 2.344082e-06, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Di... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1638 | Q67 | What is the top-associated SNP of the gene RP11-259G18.2 in Cerebellum eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for RP11-259G18.2 in Cerebellum eQTL omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 4.56e-19 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.2" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1714157', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'RP11-259G18.2', 'p_SMR_multi': 4.556951e-19, 'p_HEIDI': 1.112994e-20, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linka... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1588 | Q67 | What is the top-associated SNP of the gene EMID2 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | There are no SNPs within the gene EMID2 in Whole Brain meta-analysis mQTL omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "EMID2" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_450064', 'topRSID': 'rs12534721', 'Disease': 'PD', 'Gene': 'EMID2', 'p_SMR_multi': 0.4388202, 'p_HEIDI': 0.9989398, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_4... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1316 | Q67 | What is the top-associated SNP of the gene ZSCAN18 in Whole Brain meta-analysis mQTL omic data for LBD and is it functionally significant? | There are no SNPs within the gene ZSCAN18 in Whole Brain meta-analysis mQTL omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ZSCAN18" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_404398', 'topRSID': 'rs2547260', 'Disease': 'LBD', 'Gene': 'ZSCAN18', 'p_SMR_multi': 0.5511953, 'p_HEIDI': 0.8649661, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1779 | Q67 | What is the top-associated SNP of the gene MAPT in Whole Brain meta-analysis mQTL omic data for PSP and is it functionally significant? | The top-associated SNP for MAPT in Whole Brain meta-analysis mQTL omic data for PSP is rs8070723, which has a multi-SNP SMR p-value of 3.67e-16 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_560864', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'MAPT', 'p_SMR_multi': 2.100115e-44, 'p_HEIDI': 0.01425494, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_56... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1647 | Q67 | What is the top-associated SNP of the gene SLC9A3 in Whole Brain meta-analysis mQTL omic data for FTD and is it functionally significant? | There are no SNPs within the gene SLC9A3 in Whole Brain meta-analysis mQTL omic data that are significantly associated with FTD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SLC9A3" AND Disease = "FTD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_249090', 'topRSID': 'rs1043356', 'Disease': 'FTD', 'Gene': 'SLC9A3', 'p_SMR_multi': 0.01849509, 'p_HEIDI': 0.2474611, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1255 | Q67 | What is the top-associated SNP of the gene POLE in Whole Blood mQTL omic data for PSP and is it functionally significant? | There are no SNPs within the gene POLE in Whole Blood mQTL omic data that are significantly associated with PSP, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "POLE" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1090343', 'topRSID': 'rs5744934', 'Disease': 'PSP', 'Gene': 'POLE', 'p_SMR_multi': 0.0450088, 'p_HEIDI': 0.4287437, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_1090347', 'topR... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1675 | Q67 | What is the top-associated SNP of the gene SNCA in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for SNCA in Whole Brain meta-analysis mQTL omic data for PD is rs1372520, which has a multi-SNP SMR p-value of 6.94e-11 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SNCA" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_432414', 'topRSID': 'rs3756059', 'Disease': 'PD', 'Gene': 'SNCA', 'p_SMR_multi': 2.653319e-12, 'p_HEIDI': 9.429443e-19, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1801 | Q67 | What is the top-associated SNP of the gene WNT3 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for PD and is it functionally significant? | The top-associated SNP for WNT3 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for PD is rs8069437, which has a multi-SNP SMR p-value of 1.89e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "WNT3" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1435923', 'topRSID': 'rs8069437', 'Disease': 'PD', 'Gene': 'WNT3', 'p_SMR_multi': 1.885582e-06, 'p_HEIDI': 0.002074094, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'association meets significance threshol... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.759 | Q67 | What is the top-associated SNP of the gene ZNF300P1 in Hippocampus eQTL omic data for AD and is it functionally significant? | There are no SNPs within the gene ZNF300P1 in Hippocampus eQTL omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ZNF300P1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%hippocampus eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1377453', 'topRSID': 'rs12659118', 'Disease': 'AD', 'Gene': 'ZNF300P1', 'p_SMR_multi': 0.7350734, 'p_HEIDI': 0.7428937, 'Omic_tissue': 'Hippocampus', 'Omic_type': 'Hippocampus eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.616 | Q67 | What is the top-associated SNP of the gene GAL3ST1 in Whole Blood mQTL omic data for PD and is it functionally significant? | There are no SNPs within the gene GAL3ST1 in Whole Blood mQTL omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "GAL3ST1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1012940', 'topRSID': 'rs42941', 'Disease': 'PD', 'Gene': 'GAL3ST1', 'p_SMR_multi': 0.1035074, 'p_HEIDI': 0.7261276, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_1012941', 'topR... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1045 | Q67 | What is the top-associated SNP of the gene ARHGAP27 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for ARHGAP27 in Whole Brain meta-analysis mQTL omic data for PD is rs62065376, which has a multi-SNP SMR p-value of 1.13e-11 and a HEIDI of 0.31, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARHGAP27" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_491057', 'topRSID': 'rs62065376', 'Disease': 'PD', 'Gene': 'ARHGAP27', 'p_SMR_multi': 1.134698e-11, 'p_HEIDI': 0.3072466, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.788 | Q67 | What is the top-associated SNP of the gene STX1B in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for STX1B in Whole Blood mQTL omic data for PD is rs35961830, which has a multi-SNP SMR p-value of 1.40e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "STX1B" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_974667', 'topRSID': 'rs9796794', 'Disease': 'PD', 'Gene': 'STX1B', 'p_SMR_multi': 1.979272e-07, 'p_HEIDI': 0.003601113, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1690 | Q67 | What is the top-associated SNP of the gene LINC00578 in Whole Brain meta-analysis mQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene LINC00578 in Whole Brain meta-analysis mQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LINC00578" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_148619', 'topRSID': 'rs11915692', 'Disease': 'ALS', 'Gene': 'LINC00578', 'p_SMR_multi': 0.3840676, 'p_HEIDI': 0.8596002, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_t... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.997 | Q67 | What is the top-associated SNP of the gene RP4-604G5.1 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for RP4-604G5.1 in Whole Blood mQTL omic data for AD is rs2525539, which has a multi-SNP SMR p-value of 2.55e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP4-604G5.1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_585962', 'topRSID': 'rs2525539', 'Disease': 'AD', 'Gene': 'RP4-604G5.1', 'p_SMR_multi': 2.5452e-10, 'p_HEIDI': 8.218981e-05, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage D... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.499 | Q67 | What is the top-associated SNP of the gene GAK in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for GAK in Whole Brain meta-analysis mQTL omic data for PD is rs73207791, which has a multi-SNP SMR p-value of 7.41e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "GAK" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_429832', 'topRSID': 'rs11248057', 'Disease': 'PD', 'Gene': 'GAK', 'p_SMR_multi': 1.488653e-10, 'p_HEIDI': 1.165356e-06, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1320 | Q67 | What is the top-associated SNP of the gene RP11-707O23.5 in Tibial Nerve eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for RP11-707O23.5 in Tibial Nerve eQTL omic data for PSP is rs12373139, which has a multi-SNP SMR p-value of 1.03e-28 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-707O23.5" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%tibial nerve eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1336286', 'topRSID': 'rs12373139', 'Disease': 'PSP', 'Gene': 'RP11-707O23.5', 'p_SMR_multi': 1.0309360000000002e-28, 'p_HEIDI': 5.711562e-19, 'Omic_tissue': 'Tibial Nerve', 'Omic_type': 'Tibial Nerve eQTL', 'func_sig': 'association meets significance threshold but shows signs of... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.281 | Q67 | What is the top-associated SNP of the gene RN7SL199P in Prefrontal Cortex eQTL omic data for PD and is it functionally significant? | The top-associated SNP for RN7SL199P in Prefrontal Cortex eQTL omic data for PD is rs2950694, which has a multi-SNP SMR p-value of 4.16e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RN7SL199P" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%prefrontal cortex eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1242286', 'topRSID': 'rs2950694', 'Disease': 'PD', 'Gene': 'RN7SL199P', 'p_SMR_multi': 4.158155e-10, 'p_HEIDI': 0.002446177, 'Omic_tissue': 'Prefrontal Cortex', 'Omic_type': 'Prefrontal Cortex eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkag... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1848 | Q67 | What is the top-associated SNP of the gene LRRC37A2 in Hypothalamus eQTL omic data for AD and is it functionally significant? | The top-associated SNP for LRRC37A2 in Hypothalamus eQTL omic data for AD is rs8073146, which has a multi-SNP SMR p-value of 1.59e-06 and a HEIDI of 0.49, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%hypothalamus eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1454364', 'topRSID': 'rs8073146', 'Disease': 'AD', 'Gene': 'LRRC37A2', 'p_SMR_multi': 1.585859e-06, 'p_HEIDI': 0.4894522, 'Omic_tissue': 'Hypothalamus', 'Omic_type': 'Hypothalamus eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.363 | Q67 | What is the top-associated SNP of the gene RP11-196G11.2 in Tibial Nerve eQTL omic data for AD and is it functionally significant? | The top-associated SNP for RP11-196G11.2 in Tibial Nerve eQTL omic data for AD is rs55979739, which has a multi-SNP SMR p-value of 2.58e-06 and a HEIDI of 0.01, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-196G11.2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%tibial nerve eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1291234', 'topRSID': 'rs55979739', 'Disease': 'AD', 'Gene': 'RP11-196G11.2', 'p_SMR_multi': 2.582734e-06, 'p_HEIDI': 0.01107903, 'Omic_tissue': 'Tibial Nerve', 'Omic_type': 'Tibial Nerve eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1179 | Q67 | What is the top-associated SNP of the gene MAPT in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for MAPT in Whole Blood mQTL omic data for PD is rs62056790, which has a multi-SNP SMR p-value of 8.71e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_948891', 'topRSID': 'rs62063271', 'Disease': 'PD', 'Gene': 'MAPT', 'p_SMR_multi': 6.382411e-15, 'p_HEIDI': 2.368028e-06, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.239 | Q67 | What is the top-associated SNP of the gene GAK in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for GAK in Whole Brain meta-analysis mQTL omic data for PD is rs748483, which has a multi-SNP SMR p-value of 1.21e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "GAK" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_429832', 'topRSID': 'rs11248057', 'Disease': 'PD', 'Gene': 'GAK', 'p_SMR_multi': 1.488653e-10, 'p_HEIDI': 1.165356e-06, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.557 | Q67 | What is the top-associated SNP of the gene NFYA in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for NFYA in Whole Blood mQTL omic data for AD is rs72856298, which has a multi-SNP SMR p-value of 5.53e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "NFYA" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_622639', 'topRSID': 'rs72856298', 'Disease': 'AD', 'Gene': 'NFYA', 'p_SMR_multi': 3.336665e-10, 'p_HEIDI': 1.123977e-10, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1870 | Q67 | What is the top-associated SNP of the gene LRRC37A2 in Prefrontal Cortex eQTL omic data for PD and is it functionally significant? | The top-associated SNP for LRRC37A2 in Prefrontal Cortex eQTL omic data for PD is rs3874943, which has a multi-SNP SMR p-value of 1.52e-13 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A2" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%prefrontal cortex eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1242285', 'topRSID': 'rs3874943', 'Disease': 'PD', 'Gene': 'LRRC37A2', 'p_SMR_multi': 1.515393e-13, 'p_HEIDI': 2.082353e-09, 'Omic_tissue': 'Prefrontal Cortex', 'Omic_type': 'Prefrontal Cortex eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkag... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1915 | Q67 | What is the top-associated SNP of the gene RELB in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for RELB in Whole Blood mQTL omic data for AD is rs75654248, which has a multi-SNP SMR p-value of 3.19e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RELB" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_637442', 'topRSID': 'rs75654248', 'Disease': 'AD', 'Gene': 'RELB', 'p_SMR_multi': 3.188959e-10, 'p_HEIDI': 0.0005592422, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.211 | Q67 | What is the top-associated SNP of the gene ZDHHC14 in Whole Brain meta-analysis mQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene ZDHHC14 in Whole Brain meta-analysis mQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ZDHHC14" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_164826', 'topRSID': 'rs11961073', 'Disease': 'ALS', 'Gene': 'ZDHHC14', 'p_SMR_multi': 0.007035367, 'p_HEIDI': 0.0354973, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_t... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1922 | Q67 | What is the top-associated SNP of the gene TMEM175 in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for TMEM175 in Whole Blood mQTL omic data for PD is rs6813110, which has a multi-SNP SMR p-value of 4.73e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TMEM175" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_996283', 'topRSID': 'rs6813110', 'Disease': 'PD', 'Gene': 'TMEM175', 'p_SMR_multi': 2.618289e-11, 'p_HEIDI': 0.0001221027, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dis... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1561 | Q67 | What is the top-associated SNP of the gene IDUA in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for IDUA in Whole Blood mQTL omic data for PD is rs11936407, which has a multi-SNP SMR p-value of 1.16e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "IDUA" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_996313', 'topRSID': 'rs11936407', 'Disease': 'PD', 'Gene': 'IDUA', 'p_SMR_multi': 1.158943e-09, 'p_HEIDI': 4.775076e-12, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.60 | Q67 | What is the top-associated SNP of the gene DNAH17 in Whole Blood mQTL omic data for LBD and is it functionally significant? | There are no SNPs within the gene DNAH17 in Whole Blood mQTL omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "DNAH17" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_891128', 'topRSID': 'rs8081752', 'Disease': 'LBD', 'Gene': 'DNAH17', 'p_SMR_multi': 0.1189337, 'p_HEIDI': 0.2130895, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_891131', 'topR... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1835 | Q67 | What is the top-associated SNP of the gene RWDD2B in Nucleus Accumbens Basal Ganglia omic data for PD and is it functionally significant? | There are no SNPs within the gene RWDD2B in Nucleus Accumbens Basal Ganglia omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RWDD2B" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%nucleus accumbens basal ganglia%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1730527', 'topRSID': 'rs2832155', 'Disease': 'PD', 'Gene': 'RWDD2B', 'p_SMR_multi': 0.2084891, 'p_HEIDI': 0.5135451, 'Omic_tissue': 'Nucleus Accumbens Basal', 'Omic_type': 'Nucleus Accumbens Basal Ganglia', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1906 | Q67 | What is the top-associated SNP of the gene DNAH1 in Cerebellum eQTL omic data for FTD and is it functionally significant? | There are no SNPs within the gene DNAH1 in Cerebellum eQTL omic data that are significantly associated with FTD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "DNAH1" AND Disease = "FTD" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1697165', 'topRSID': 'rs724801', 'Disease': 'FTD', 'Gene': 'DNAH1', 'p_SMR_multi': 0.9475356, 'p_HEIDI': 0.8859624, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_11927', 'topRSID'... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1578 | Q67 | What is the top-associated SNP of the gene RP11-902B17.1 in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | There are no SNPs within the gene RP11-902B17.1 in Whole Blood eQTL eQTLgen omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-902B17.1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1500229', 'topRSID': 'rs7149180', 'Disease': 'AD', 'Gene': 'RP11-902B17.1', 'p_SMR_multi': 0.1584766, 'p_HEIDI': 0.4619988, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.368 | Q67 | What is the top-associated SNP of the gene DOC2A in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for DOC2A in Whole Brain meta-analysis mQTL omic data for AD is rs8060511, which has a multi-SNP SMR p-value of 2.06e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "DOC2A" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_109454', 'topRSID': 'rs10871451', 'Disease': 'AD', 'Gene': 'DOC2A', 'p_SMR_multi': 7.531563e-08, 'p_HEIDI': 0.000390338, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.511 | Q67 | What is the top-associated SNP of the gene ST14 in Whole Brain meta-analysis mQTL omic data for LBD and is it functionally significant? | There are no SNPs within the gene ST14 in Whole Brain meta-analysis mQTL omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ST14" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_375483', 'topRSID': 'rs2124059', 'Disease': 'LBD', 'Gene': 'ST14', 'p_SMR_multi': 0.1414094, 'p_HEIDI': 0.9519532, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_37... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.815 | Q67 | What is the top-associated SNP of the gene ARHGAP27 in Whole Brain meta-analysis mQTL omic data for PSP and is it functionally significant? | The top-associated SNP for ARHGAP27 in Whole Brain meta-analysis mQTL omic data for PSP is rs11012, which has a multi-SNP SMR p-value of 9.28e-28 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARHGAP27" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_560834', 'topRSID': 'rs11012', 'Disease': 'PSP', 'Gene': 'ARHGAP27', 'p_SMR_multi': 9.282341e-28, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Li... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1122 | Q67 | What is the top-associated SNP of the gene KANSL1 in Cortex eQTL metaBrain omic data for PD and is it functionally significant? | The top-associated SNP for KANSL1 in Cortex eQTL metaBrain omic data for PD is rs169201, which has a multi-SNP SMR p-value of 8.23e-15 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cortex eqtl metabrain%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1147256', 'topRSID': 'rs169201', 'Disease': 'PD', 'Gene': 'KANSL1', 'p_SMR_multi': 8.230037e-15, 'p_HEIDI': 1.576563e-06, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL metaBrain', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dise... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1731 | Q67 | What is the top-associated SNP of the gene PRR21 in Whole Blood mQTL omic data for PSP and is it functionally significant? | There are no SNPs within the gene PRR21 in Whole Blood mQTL omic data that are significantly associated with PSP, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PRR21" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1076456', 'topRSID': 'rs10933554', 'Disease': 'PSP', 'Gene': 'PRR21', 'p_SMR_multi': 0.8304816, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_1076457', 'topR... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1216 | Q67 | What is the top-associated SNP of the gene MAPT in Whole Blood mQTL omic data for PSP and is it functionally significant? | The top-associated SNP for MAPT in Whole Blood mQTL omic data for PSP is rs169201, which has a multi-SNP SMR p-value of 2.38e-42 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1041740', 'topRSID': 'rs169201', 'Disease': 'PSP', 'Gene': 'MAPT', 'p_SMR_multi': 3.1929999999999995e-44, 'p_HEIDI': 3.11336e-12, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Link... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
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